Matches in Nanopublications for { ?s ?p "Finally, we found that overexpression of a mutant form of C/EBPbeta, lacking the consensus ERK phosphorylation site at Thr-235 (T235A), blocked the ability of F/R and PMA to induce SOCS-3 expression in COS1 cells in a dominant-negative fashion. Together, these results implicate ERK-dependent C/EBPbeta phosphorylation and activation as essential requirements for effective SOCS-3 induction in response to cyclic AMP and PKC activation in COS1 cells." ?g. }
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- _5 value "Finally, we found that overexpression of a mutant form of C/EBPbeta, lacking the consensus ERK phosphorylation site at Thr-235 (T235A), blocked the ability of F/R and PMA to induce SOCS-3 expression in COS1 cells in a dominant-negative fashion. Together, these results implicate ERK-dependent C/EBPbeta phosphorylation and activation as essential requirements for effective SOCS-3 induction in response to cyclic AMP and PKC activation in COS1 cells." provenance.
- _4 value "Finally, we found that overexpression of a mutant form of C/EBPbeta, lacking the consensus ERK phosphorylation site at Thr-235 (T235A), blocked the ability of F/R and PMA to induce SOCS-3 expression in COS1 cells in a dominant-negative fashion. Together, these results implicate ERK-dependent C/EBPbeta phosphorylation and activation as essential requirements for effective SOCS-3 induction in response to cyclic AMP and PKC activation in COS1 cells." provenance.