Matches in Nanopublications for { ?s ?p "HIF-1a N-TAD partially overlaps with the oxygenregulated degradation box and consequently, when transiently expressed in cells, the minimal N-TAD fragment is completely degraded under normoxic conditions (under which no N-TAD-mediated transactivation activity is observed [16,17]). Functional data indicate that the activity of this domain can be enhanced by the transcriptional coactivator CBP/p300 [16]." ?g. }
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- _6 value "HIF-1a N-TAD partially overlaps with the oxygenregulated degradation box and consequently, when transiently expressed in cells, the minimal N-TAD fragment is completely degraded under normoxic conditions (under which no N-TAD-mediated transactivation activity is observed [16,17]). Functional data indicate that the activity of this domain can be enhanced by the transcriptional coactivator CBP/p300 [16]." provenance.