Matches in Nanopublications for { ?s ?p "Other novel E2F-regulated genes, identified using the DNA microarray analysis, are involved in mitosis and DNA repair. The identification of mitotic genes, including the kinases Bub1b and cdc2, as E2F-regulated genes indicates that E2F affects cell cycle progression both at the S-phase and during mitosis. The molecular mechanism(s) of E2F-dependent regulation of mitotic genes is currently being studied. The identification of DNA repair genes, including MSH2, MSH6 and BRCA1, as E2F-regulated genes raises the possibility that E2F plays a role in the response to DNA damage. This notion is supported by recent reports demonstrating that various DNA damaging agents induce an increase in E2F-1 protein level." ?g. }
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- _5 value "Other novel E2F-regulated genes, identified using the DNA microarray analysis, are involved in mitosis and DNA repair. The identification of mitotic genes, including the kinases Bub1b and cdc2, as E2F-regulated genes indicates that E2F affects cell cycle progression both at the S-phase and during mitosis. The molecular mechanism(s) of E2F-dependent regulation of mitotic genes is currently being studied. The identification of DNA repair genes, including MSH2, MSH6 and BRCA1, as E2F-regulated genes raises the possibility that E2F plays a role in the response to DNA damage. This notion is supported by recent reports demonstrating that various DNA damaging agents induce an increase in E2F-1 protein level." provenance.
- _5 value "Other novel E2F-regulated genes, identified using the DNA microarray analysis, are involved in mitosis and DNA repair. The identification of mitotic genes, including the kinases Bub1b and cdc2, as E2F-regulated genes indicates that E2F affects cell cycle progression both at the S-phase and during mitosis. The molecular mechanism(s) of E2F-dependent regulation of mitotic genes is currently being studied. The identification of DNA repair genes, including MSH2, MSH6 and BRCA1, as E2F-regulated genes raises the possibility that E2F plays a role in the response to DNA damage. This notion is supported by recent reports demonstrating that various DNA damaging agents induce an increase in E2F-1 protein level." provenance.