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- _5 value "PTEN induces cell cycle arrest and/or apoptosis associated with the downregulation of Akt activity and that dominant active Akt can rescue cells from PTEN inhibition In addition to showing increased levels, IRS-2 was tyrosine phosphorylated and associated with p85, proving that PTEN was able to stimulate the liganddependent activation of IRS-2 necessary for insulin signaling" provenance.
- _5 value "PTEN induces cell cycle arrest and/or apoptosis associated with the downregulation of Akt activity and that dominant active Akt can rescue cells from PTEN inhibition In addition to showing increased levels, IRS-2 was tyrosine phosphorylated and associated with p85, proving that PTEN was able to stimulate the liganddependent activation of IRS-2 necessary for insulin signaling" provenance.