Matches in Nanopublications for { ?s ?p "Recently published data have revealed rapid up-regulation of Akt activity in isolated skeletal muscle subjected to passive stretch, which appears specific to fast-twitch muscle (Sakamoto et al. 2003). The stretch-induced activation of Akt is completely blocked through pretreatment with wortmannin, an inhibitor of PI3K. In other studies phosphorylation of both 4E-BP1 and S6K1 has been shown to be enhanced in response to muscle loading (Baar & Esser, 1999; Bodine et al. 2001; Nader & Esser, 2001; Rommel et al. 2001) and positively contributes to the up-regulation of select gene expression necessary to elicit long-term increases in skeletal muscle accretion." ?g. }
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- _3 value "Recently published data have revealed rapid up-regulation of Akt activity in isolated skeletal muscle subjected to passive stretch, which appears specific to fast-twitch muscle (Sakamoto et al. 2003). The stretch-induced activation of Akt is completely blocked through pretreatment with wortmannin, an inhibitor of PI3K. In other studies phosphorylation of both 4E-BP1 and S6K1 has been shown to be enhanced in response to muscle loading (Baar & Esser, 1999; Bodine et al. 2001; Nader & Esser, 2001; Rommel et al. 2001) and positively contributes to the up-regulation of select gene expression necessary to elicit long-term increases in skeletal muscle accretion." provenance.
- _3 value "Recently published data have revealed rapid up-regulation of Akt activity in isolated skeletal muscle subjected to passive stretch, which appears specific to fast-twitch muscle (Sakamoto et al. 2003). The stretch-induced activation of Akt is completely blocked through pretreatment with wortmannin, an inhibitor of PI3K. In other studies phosphorylation of both 4E-BP1 and S6K1 has been shown to be enhanced in response to muscle loading (Baar & Esser, 1999; Bodine et al. 2001; Nader & Esser, 2001; Rommel et al. 2001) and positively contributes to the up-regulation of select gene expression necessary to elicit long-term increases in skeletal muscle accretion." provenance.