Matches in Nanopublications for { ?s ?p "The treatment with 4-OHT induced expression of Bim and Puma in FOXO3(A3):ER-infected BMMCs but not in control cells (Figure 6C). This indicates that FOXO3a is involved not only in regulating the transcription of Bim, as previously described,26 but also identifies Puma as a FOXO3a downstream target in mast cells. The transcription factor FOXO3a has been shown to regulate the BH3-only protein Bim (Dijkers PF, Curr Biol. 2000) and also was recently described to control Puma expression in response to growth factor deprivation in lymphoid cells and mouse embryonic fibroblasts (You H, J Exp Med. 2006)" ?g. }
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- _5 value "The treatment with 4-OHT induced expression of Bim and Puma in FOXO3(A3):ER-infected BMMCs but not in control cells (Figure 6C). This indicates that FOXO3a is involved not only in regulating the transcription of Bim, as previously described,26 but also identifies Puma as a FOXO3a downstream target in mast cells. The transcription factor FOXO3a has been shown to regulate the BH3-only protein Bim (Dijkers PF, Curr Biol. 2000) and also was recently described to control Puma expression in response to growth factor deprivation in lymphoid cells and mouse embryonic fibroblasts (You H, J Exp Med. 2006)" provenance.
- _5 value "The treatment with 4-OHT induced expression of Bim and Puma in FOXO3(A3):ER-infected BMMCs but not in control cells (Figure 6C). This indicates that FOXO3a is involved not only in regulating the transcription of Bim, as previously described,26 but also identifies Puma as a FOXO3a downstream target in mast cells. The transcription factor FOXO3a has been shown to regulate the BH3-only protein Bim (Dijkers PF, Curr Biol. 2000) and also was recently described to control Puma expression in response to growth factor deprivation in lymphoid cells and mouse embryonic fibroblasts (You H, J Exp Med. 2006)" provenance.