Matches in Nanopublications for { ?s ?p "We now show for the first time that suppression of T-bet ameliorates EAE by limiting the differentiation of autoreactive Th1 cells, as well as inhibiting pathogenic Th17 cells via regulation of IL-23R. (from text:) We consistently found that the number of Th17 cells in the CNS of EAE-affected mice was highest at the acute phase of disease as shown in Fig. 4 and decreased over time as shown in Fig. 5. However, the number of Th17 cells in the CNS was usually undetectable in the siRNA-T-bet-treated mice at all time points." ?g. }
Showing items 1 to 1 of
1
with 100 items per page.
- _4 value "We now show for the first time that suppression of T-bet ameliorates EAE by limiting the differentiation of autoreactive Th1 cells, as well as inhibiting pathogenic Th17 cells via regulation of IL-23R. (from text:) We consistently found that the number of Th17 cells in the CNS of EAE-affected mice was highest at the acute phase of disease as shown in Fig. 4 and decreased over time as shown in Fig. 5. However, the number of Th17 cells in the CNS was usually undetectable in the siRNA-T-bet-treated mice at all time points." provenance.