Matches in Nanopublications for { ?s ?p "the IFN-a receptor lacks intrinsic kinase activity and instead uses Jak1 and Tyk2 to initiate signal transduction. Ligandinduced dimerization of IFNAR-1 and IFNAR-2 allows juxtaposition and activation of the associated Jaks, leading to activation of downstream signaling pathways (e.g., STAT1, -2, and -3)" ?g. }
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- _6 value "the IFN-a receptor lacks intrinsic kinase activity and instead uses Jak1 and Tyk2 to initiate signal transduction. Ligandinduced dimerization of IFNAR-1 and IFNAR-2 allows juxtaposition and activation of the associated Jaks, leading to activation of downstream signaling pathways (e.g., STAT1, -2, and -3)" provenance.
- _6 value "the IFN-a receptor lacks intrinsic kinase activity and instead uses Jak1 and Tyk2 to initiate signal transduction. Ligandinduced dimerization of IFNAR-1 and IFNAR-2 allows juxtaposition and activation of the associated Jaks, leading to activation of downstream signaling pathways (e.g., STAT1, -2, and -3)" provenance.
- _6 value "the IFN-a receptor lacks intrinsic kinase activity and instead uses Jak1 and Tyk2 to initiate signal transduction. Ligandinduced dimerization of IFNAR-1 and IFNAR-2 allows juxtaposition and activation of the associated Jaks, leading to activation of downstream signaling pathways (e.g., STAT1, -2, and -3)" provenance.
- _6 value "the IFN-a receptor lacks intrinsic kinase activity and instead uses Jak1 and Tyk2 to initiate signal transduction. Ligandinduced dimerization of IFNAR-1 and IFNAR-2 allows juxtaposition and activation of the associated Jaks, leading to activation of downstream signaling pathways (e.g., STAT1, -2, and -3)" provenance.