Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Malaria+is+transmitted+by+mosquitoes. assertion.
- assertion asSentence LacY+exhibits+specificity+directed+toward+the+galactopyranosyl+moiety+of+the+glycoside+to+be+transported. assertion.
- assertion asSentence FnrS+extends+the+FNR+regulon+and+increases+the+efficiency+of+anaerobic+metabolism+by+repressing+the+synthesis+of+enzymes+that+are+not+needed+under+these+conditions. assertion.
- assertion asSentence The+replication+checkpoint+suppresses+the+formation+of+Rad52+foci+in+an+Mrc1-dependent+manner+and+prevents+homologous+recombination+%28HR%29+at+chromosome+breaks+induced+by+the+HO+endonuclease. assertion.
- assertion asSentence Following+autophagy+induction+the+function+of+Sec2+and+Sec4+are+diverted+to+direct+membrane+flow+to+autophagosome+formation. assertion.
- assertion asSentence That+Cdc5+promotes+Cdc14+release+primarily+by+stimulating+the+degradation+of+Swe1%2C+the+inhibitory+kinase+for+mitotic+Cdk. assertion.
- assertion asSentence Mid1+function+is+influenced+by+Spa2+function+through+polarized+morphogenesis. assertion.
- assertion asSentence Cofilin-mediated+actin+filament+flux+is+required+for+the+multiple+steps+of+endocytic+trafficking. assertion.
- assertion asSentence Shq1p+binds+the+pseudourydilating+enzyme+Cbf5p+through+the+C-terminal+domain%2C+in+synergy+with+the+N-terminal+domain. assertion.
- assertion asSentence Increased+dosage+of+either+RCN1+or+RSA3+improves+tolerance+of+S288C+and+M2+to+toxic+levels+of+ethanol. assertion.
- assertion asSentence Syt1p+promoted+activation+of+Arl1p+and+recruitment+of+a+golgin+protein%2C+Imh1p%2C+to+the+Golgi. assertion.
- assertion asSentence Mrt4+and+P0+bind+to+the+same+site+in+the+25S+rRNA. assertion.
- assertion asSentence The+Smc5-Smc6+complex+and+SUMO+modification+of+Rad52+regulates+recombinational+repair+at+the+ribosomal+gene+locus+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Rather+than+directly+targeting+Elp1%2C+the+Hrr25+kinase+indirectly+affects+Elp1+phosphorylation+states+through+control+of+Sit4-dependent+dephosphorylation+of+Elp1. assertion.
- assertion asSentence Cdc50p-Drs2p+plays+an+important+role+in+the+Arf1p%2FGcs1-mediated+formation+of+clathrin-coated+vesicles+for+the+retrieval+pathway+from+early+endosomes+to+the+trans-Golgi+network. assertion.
- assertion asSentence Membrane+that+contains+Atg9+is+delivered+to+the+autophagosome+from+the+Golgi-endosomal+system+rather+than+from+the+ER+or+mitochondria. assertion.
- assertion asSentence Protein+deacetylation+is+the+only+essential+function+of+Sir2+in+creating+silenced+chromatin. assertion.
- assertion asSentence Ubiquitin-mediated+degradation+of+Rpn4+is+controlled+by+a+phosphorylation-dependent+ubiquitylation+signal. assertion.
- assertion asSentence Ptc1p+and+Nbp2p+regulate+endoplasmic+reticulum+inheritance+through+the+cell+wall+integrity+%28CWI%29+mitogen-activated+protein+kinase+%28MAPK%29+pathway+by+modulating+the+MAPK%2C+Slt2p. assertion.
- assertion asSentence Are+differences+between+Dad1+from+C.+albicans+and+S.+cerevisiae. assertion.
- assertion asSentence Yos9p+plays+a+critical+role+in+the+bipartite+recognition+of+terminally+misfolded+glycoproteins. assertion.
- assertion asSentence Yos9+slows+the+degradation+of+the+unglycosylated+ERAD+substrate+CPY+%2A0000. assertion.
- assertion asSentence Tvp23p+performs+a+partially+redundant+function+in+retrograde+transport+from+the+early+endosome+to+the+late+Golgi. assertion.
- assertion asSentence Viability+of+mother+cells+in+liquid+culture+is+regulated+by+SIR2+and+FOB1%2C+two+opposing+regulators+of+RLS+in+yeast. assertion.
- assertion asSentence Dop1p+localizes+to+endosomes+and+exists+in+a+complex+with+Neo1p-Ysl2p-Arl1p. assertion.
- assertion asSentence A+frameshift+mutation+in+a+mononucleotide+run+of+eight+consecutive+T%27s+in+the+coding+region+SSY1+causes+dramatic+differences+in+gene-expression+levels+of+key+genes+involved+in+amino+acid+biosynthesis. assertion.
- assertion asSentence Sec1p+couples+exocyst-mediated+vesicle+tethering+with+SNARE-mediated+docking+and+fusion. assertion.
- assertion asSentence Full-length+New1+broke+the+Sup35NM+amyloid+fibrils+in+an+ATP-dependent+manner. assertion.
- assertion asSentence Ume6p+degradation+is+required+for+normal+meiotic+gene+induction+and+meiotic+progression. assertion.
- assertion asSentence The+regulation+of+Snf1+dephosphorylation+is+imparted+through+a+dynamic+competition+between+the+Glc7+phosphatase+and+the+Snf1+kinase+for+binding+to+the+PP1+regulatory+subunit+Reg1. assertion.
- assertion asSentence Tel1p+targets+telomerase+to+the+DNA+ends+most+in+need+of+extension. assertion.
- assertion asSentence Tel1+kinase+and+subtelomere-bound+Tbf1+mediate+preferential+elongation+of+short+telomeres+by+telomerase+in+yeast. assertion.
- assertion asSentence Mec1+and+Tel1+promote+meiotic+interhomolog+recombination+by+targeting+the+axial+element+protein+Hop1. assertion.
- assertion asSentence K4+demethylation+has+two+roles+at+GAL1%2C+first+to+establish+appropriate+levels+of+K4+methylation+during+gene+activation+and+second+to+remove+K4+trimethylation+during+the+attenuation+phase+of+transcription. assertion.
- assertion asSentence Human+and+yeast+zeta-crystallins+bind+AU-rich+elements+in+RNA. assertion.
- assertion asSentence Mono-ubiquitination+of+PCNA+is+induced+by+nucleotide+misincorporation+by+DNA+polymerase+alpha. assertion.
- assertion asSentence The+histone+chaperone+Asf1+increases+the+rate+of+histone+eviction+at+the+PHO5+and+PHO8+promoters. assertion.
- assertion asSentence The+Ccz1p-Mon1p-Ypt7p+complex+is+involved+in+fusion+of+transport+vesicles+to+multiple+target+membranes+in+yeast+cells. assertion.
- assertion asSentence The+Cdc13+telomere+cap+coordinates+Mec1+and+Tel1+accumulation+rather+than+simply+covering+the+DNA+ends+at+telomeres. assertion.
- assertion asSentence Mec1+and+Tel1+promote+meiotic+interhomolog+recombination+by+targeting+the+axial+element+protein+Hop1. assertion.
- assertion asSentence Cdc28-Mec1+activity+inhibits+the+recruitment+of+Rad52+to+both+sites+of+DNA+damage+and+stalled+replication+forks+during+the+intra-S-phase+checkpoint. assertion.
- assertion asSentence The+N-terminal+eRF1+fragment+is+indispensable+for+cell+viability+of+nonsense+mutants+due+to+the+involvement+in+termination+of+translation. assertion.
- assertion asSentence Point+mutants+of+Saccharomyces+cerevisiae+eRF1+display+significant+variability+in+their+stop+codon+read-through+phenotypes. assertion.
- assertion asSentence Mutation+of+a+conserved+active+site+residue+converts+tyrosyl-DNA+phosphodiesterase+I+into+a+DNA+topoisomerase+I-dependent+poison. assertion.
- assertion asSentence The+SWI%2FSNF+chromatin-remodeling+complex+is+recruited+to+DNA+lesions+by+damage-recognition+proteins+to+increase+DNA+accessibility+for+NER+in+chromatin. assertion.
- assertion asSentence Additional+or+alternative+binding+sites+exist+on+the+the+clathrin+heavy+chain+%28HC%29+N-terminal+domain+propeller+to+help+facilitate+the+recruitment+of+clathrin+to+sites+of+vesicle+formation. assertion.
- assertion asSentence Atg1%2C+PKA+directly+phosphorylates+Atg13+in+a+Tor-dependent+manner. assertion.
- assertion asSentence The+direct+control+of+the+Atg1+complex+by+Tor+complex1+induces+autophagy. assertion.
- assertion asSentence Metalloregulation+of+Ace1+and+Mac1+occurs+independently. assertion.
- assertion asSentence Prp43+hydrolyzes+all+common+NTPs+and+dNTPs+and+unwinds+short+5%27%2F3%27+tailed+RNA%2FDNA+duplexes+in+an+ATP-dependent+fashion. assertion.
- assertion asSentence Ume6p+degradation+is+required+for+normal+meiotic+gene+induction+and+meiotic+progression. assertion.
- assertion asSentence LC+binding+to+Sla2p+positively+regulates+Sla2p+for+efficient+endocytic+vesicle+formation. assertion.
- assertion asSentence The+N-terminal+domain+is+required+for+the+proper+cellular+localization+of+Knr4+at+sites+of+polarized+growth+during+vegetative+growth+and+sexual+differentiation+%28bud+tip+and+%27shmoo%27+tip%29. assertion.
- assertion asSentence Cbp1+is+loosely+associated+with+the+mitochondrial+membrane+through+weak+hydrophobic+interactions+and+it+is+part+of+a+single+900%2C000-Da+complex.+. assertion.
- assertion asSentence The+histone+chaperone+Asf1+increases+the+rate+of+histone+eviction+at+the+PHO5+and+PHO8+promoters. assertion.
- assertion asSentence Functional+switching+of+Asf1+between+states+that+close+and+open+chromatin+is+under+physiological+control+by+a+pathway+that+depends+on+Rtt109. assertion.
- assertion asSentence The+hFBH1+helicase+is+a+functional+human+orthologue+of+budding+yeast+Srs2+that+also+possesses+self-regulation+properties+necessary+to+execute+its+recombination+functions. assertion.
- assertion asSentence The+regulation+of+Dip5+endocytosis+is+accomplished+by+dynamic+recruitment+of+Rsp5+via+Aly2. assertion.
- assertion asSentence Key+basic+residues+within+the+predicted+nuclear+localization+signal+of+Scp160+can+be+altered+without+severely+affecting+Scp160+function. assertion.
- assertion asSentence The+GTPase-activating+activity+of+Bfa1p-Bub2p+is+responsible+for+the+mitotic+arrest+caused+by+spindle+damage+and+Bfa1p+overproduction. assertion.
- assertion asSentence Tec1+protein+stability+is+under+control+of+the+nutrient-sensitive+target+of+rapamycin+complex+1+%28TORC1%29+signaling+pathway+via+the+Tip41-Tap42-Sit4+branch. assertion.
- assertion asSentence Casein+kinase+I+plays+a+role+in+fungal+nutritional+signaling+pathways+by+phosphorylating+pathway+components+and+targeting+them+for+ubiquitination+by+SCFGrr1. assertion.
- assertion asSentence The+N-terminal+shuttle+domain+of+Erv1+is+necessary+and+sufficient+for+interaction+with+Mia40. assertion.
- assertion asSentence ASH1+mRNA+and+She2+localize+specifically+to+the+nucleolus+when+their+nuclear+export+is+blocked. assertion.
- assertion asSentence Increased+dosage+of+either+RCN1+or+RSA3+improves+tolerance+of+S288C+and+M2+to+toxic+levels+of+ethanol. assertion.
- assertion asSentence Two+different+glucose+signal+transduction+pathways+converge+on+Rgt1+to+regulate+expression+of+HXT+glucose+transporters. assertion.
- assertion asSentence Transcriptional+adaptation+from+aerobiosis+to+hypoxia+depends+on+ROX1+and+IXR1+cross-regulation. assertion.
- assertion asSentence The+deletion+of+sphingolipid+hydroxylases+changes+the+toxicity+of+ceramide+under+AUR1-repressive+conditions. assertion.
- assertion asSentence Dre2+contains+an+N-terminal+domain+whose+structure+in+solution+consists+of+a+stable+well-structured+monomer+with+an+overall+typical+S-adenosylmethionine+methyltransferase+fold+lacking+two+alpha-helices+and+a+beta-strand. assertion.
- assertion asSentence One+consequence+of+Rex1p-dependent+3%27+trimming+is+the+generation+of+aberrant+RNAs+that+are+targeted+for+decay+by+Trf4p. assertion.
- assertion asSentence Multiple+thiamine+%28THI%29+genes+in+Saccharomyces+cerevisiae+are+also+regulated+by+the+intracellular+NAD%28%2B%29+concentration+via+the+NAD%28%2B%29-dependent+histone+deacetylase+%28HDAC%29+Hst1+and%2C+to+a+lesser+extent%2C+Sir2. assertion.
- assertion asSentence The+thiaminase+II+activity+of+Thi20p+is+involved+in+the+thiamin+salvage+pathway+by+catalyzing+the+hydrolysis+of+HMP+precursors+in+S.+cerevisiae. assertion.
- assertion asSentence The+homo-oligomerization+of+Mim1+allows+it+to+fulfil+its+function+in+promoting+the+integration+of+Tom20+into+the+mitochondrial+outer+membrane. assertion.
- assertion asSentence The+Saccharomyces+cerevisiae+Hrd1+complex+manages+three+distinct+substrate+classes. assertion.
- assertion asSentence The+combination+of+H2A-containing+nucleosome+and+free+H2A.Z-H2B+dimer+acting+as+both+effector+and+substrate+for+SWR1+governs+the+specificity+and+outcome+of+the+replacement+reaction. assertion.
- assertion asSentence Wsc1+uses+a+clathrin-dependent+NPFDD+signal%2C+Wsc2+relies+on+a+specific+lysine+residue+%28K495%29. assertion.
- assertion asSentence Mss116p+and+Pet127p+are+involved+in+modulation+of+mtRNAP+activity. assertion.
- assertion asSentence Whi2p-dependent+regulation+of+cAMP-PKA+signalling+plays+a+physiological+role+in+the+differentiation+of+yeast+colonies+by+facilitating+elaboration+of+distinct+zones+of+cell+death. assertion.
- assertion asSentence The+Ras%2FcAMP%2FPKA%2FRim15%2FMsn2%2F4+and+the+Tor%2FSch9%2FRim15%2FGis1+pathways+are+major+mediators+of+the+calorie+restriction-dependent+stress+resistance+and+life+span+extension. assertion.
- assertion asSentence Bud-localized+MEN+regulator+Lte1+prevents+Kin4+that+escapes+into+the+bud+from+associating+with+SPBs+in+the+daughter+cell. assertion.
- assertion asSentence Multiple+contacts+between+eIF2gamma+and+eIF2Bepsilon+mediate+nucleotide+exchange. assertion.
- assertion asSentence Elevated+levels+of+the+yeast+Rev1+C+terminus+confer+a+strong+dominant-negative+effect+on+viability+and+induced+mutagenesis+after+DNA+damage. assertion.
- assertion asSentence A+MEN+component%2C+protein+kinase+Dbf2-Mob1%2C+promotes+transfer+of+Cdc14+to+the+cytoplasm+and+consequent+exit+from+mitosis+by+direct+phosphorylation+of+Cdc14+on+serine+and+threonine+residues+adjacent+to+a+nuclear+localization+signal. assertion.
- assertion asSentence Shq1p+binds+the+pseudourydilating+enzyme+Cbf5p+through+the+C-terminal+domain%2C+in+synergy+with+the+N-terminal+domain. assertion.
- assertion asSentence Low+levels+of+FLO11+transcripts+are+essential+and+sufficient+for+derepression+of+FLO11+expression+and+adhesive+growth+during+amino+acid+starvation. assertion.
- assertion asSentence Hyperoxidation+of+the+endoplasmic+reticulum+is+prevented+by+attenuation+of+Ero1p+activity+through+noncatalytic+cysteine+pairs. assertion.
- assertion asSentence Deletion+of+AMD1+affects+growth+in+the+presence+of+adenine+and+impairs+purine+nucleotide+balance. assertion.
- assertion asSentence In+the+absence+of+telomerase%2C+a+very+short+telomere+is+first+maintained+in+a+pre-signalling+state+by+a+RAD52-MMS1-dependent+pathway+and+then+switches+to+a+signalling+state+leading+to+senescence+through+a+Mec1p-dependent+checkpoint. assertion.
- assertion asSentence Cytosolic+thioredoxin+peroxidase+I+is+specifically+important+in+the+protection+of+yeast+with+mitochondrial+dysfunction+due+to+its+functional+versatility+as+an+antioxidant%2C+chaperone+and+modulator+of+gene+expression. assertion.
- assertion asSentence Bur1+phosphorylates+the+Spt5+C-terminal+repeat+domain+%28CTD%29+both+in+vivo+and+in+isolated+elongation+complexes+in+vitro. assertion.
- assertion asSentence Temperature-sensitive+Saccharomyces+cerevisiae+mutants%2C+impaired+in+dolichol+kinase+%28Sec59p%29+or+dolichyl+phosphate+mannose+synthase+%28Dpm1p%29+activity+have+an+aberrant+cell+wall+composition+and+ultrastructure. assertion.
- assertion asSentence Overproduction+of+Izh2p+prevents+the+iron-dependent+induction+of+the+Fet3p+component+of+the+high-affinity+iron-uptake+system+and+is+deleterious+for+growth+in+iron-limited+medium. assertion.
- assertion asSentence That+inactivating+SOV1%2C+a+member+of+the+yeast+mitochondrial+translation+control+%28MTC%29+module%2C+causes+a+robust+Sir2-dependent+extension+of+replicative+life+span. assertion.
- assertion asSentence Mutations+of+eIF3+subunits%2C+g%2FTif35+and+i%2FTif34+diminish+induction+of+GCN4+expression. assertion.
- assertion asSentence Diacylglycerol+generated+by+Pah1p+is+important+for+lipid+droplet+biogenesis. assertion.
- assertion asSentence The+Sgs1+function+in+repair+of+DNA+replication+intermediates+can+be+uncoupled+from+its+role+in+homologous+recombinational+repair. assertion.
- assertion asSentence Gyp5p+and+Gyl1p+are+involved+in+control+of+polarized+exocytosis. assertion.
- assertion asSentence RanGAP+is+required+for+the+heterochromatin+structure+at+the+telomere. assertion.
- assertion asSentence The+interaction+between+eIF1A+and+eIF5+is+involved+in+maintaining+the+fidelity+of+start+codon+AUG+recognition+in+vivo. assertion.
- assertion asSentence eIF1+and+eIF1A+promote+an+open%2C+scanning-competent+preinitiation+complex+that+closes+upon+start+codon+recognition+and+eIF1+release+to+stabilize+ternary+complex+binding+and+clamp+down+on+mRNA. assertion.