Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Malin+is+an+E3+ubiquitin+ligase+that+binds+glycogen+synthase. assertion.
- assertion asSentence Patients+with+NHLRC1+mutations+have+a+slower+rate+of+disease+progression+than+those+with+EPM2A+mutations. assertion.
- assertion asSentence Laforin+and+malin+interact+with+misfolded+proteins+and+promote+their+degradation+through+the+ubiquitin-proteasome+system. assertion.
- assertion asSentence The+co-chaperone+carboxyl+terminus+of+the+Hsc70-interacting+protein+%28CHIP%29+stabilizes+malin+by+modulating+the+activity+of+Hsp70. assertion.
- assertion asSentence Overexpression+of+CUG2+induces+apoptosis+in+SKOV-3+cells. assertion.
- assertion asSentence NPSR1+gene+is+associated+with+reduced+risk+of+rheumatoid+arthritis. assertion.
- assertion asSentence The+LOC387715%2FHTRA1+variants+are+associated+with+polypoidal+choroidal+vasculopathy+%28PCV%29+and+wet+age-related+macular+degeneration+%28AMD%29+in+the+Japanese+population. assertion.
- assertion asSentence A+single+recurrent+mutation+in+the+5%27-UTR+of+IFITM5+causes+osteogenesis+imperfecta+type+V. assertion.
- assertion asSentence A+mutation+in+the+5%27-UTR+of+IFITM5+creates+an+in-frame+start+codon+and+causes+autosomal-dominant+osteogenesis+imperfecta+type+V+with+hyperplastic+callus. assertion.
- assertion asSentence mInsc-LGN+interaction+is+vital+for+stabilization+of+LGN+and+for+intracellular+localization+of+mInsc. assertion.
- assertion asSentence Keratinocytes+express+KACL+and+are+capable+of+stimulating+NKp65-expressing+cells+in+a+KACL-dependent+manner. assertion.
- assertion asSentence CRL4%28Cdt2%29-dependent+destruction+of+Set8+in+S+phase+preserves+genome+stability+by+preventing+aberrant+chromatin+compaction+during+DNA+synthesis. assertion.
- assertion asSentence RTL1%2C+a+paternally+expressed+gene+in+a+cluster+of+imprinted+genes+on+chromosome+14q32.2%2C+is+associated+with+upd%2814%29pat-like+and+upd%2814%29mat-like+phenotypes. assertion.
- assertion asSentence USP17+has+a+critical+role+in+cell+migration. assertion.
- assertion asSentence GOLPH3+bridges+phosphatidylinositol-4-+phosphate+and+actomyosin+%28via+MYO18A%29+to+stretch+and+shape+the+Golgi+to+promote+budding. assertion.
- assertion asSentence ShcD+binds+to+TrkC+in+a+kinase-activity-dependent+manner+through+its+PTB+and+SH2+domains. assertion.
- assertion asSentence ShcD+interacts+with+TrkB+in+a+kinase-activity-dependent+manner. assertion.
- assertion asSentence BCAR4+induces+tamoxifen+resistance+in+breast+cancer+cell+lines+by+activating+ERBB2+signaling. assertion.
- assertion asSentence p8%2FTTD-A%2C+the+tenth+subunit+of+TFIIH%2C+has+a+critical+role+in+DNA+repair+where+it+triggers+DNA+opening+by+stimulating+XPB+ATPase+activity+together+with+the+damage+recognition+factor+XPC-hHR23B. assertion.
- assertion asSentence Loss+of+let-7+expression+induces+high-mobility+group+A2+upregulation+that+represents+an+important+mechanism+in+pituitary+tumorigenesis+and+progression. assertion.
- assertion asSentence Decreased+expression+of+let-7a+miRNA+is+associated+with+laryngeal+cancer. assertion.
- assertion asSentence Reduced+let-7a+is+associated+with+gastric+cancer. assertion.
- assertion asSentence NIRF+is+frequently+upregulated+in+colorectal+cancer+and+its+oncogenicity+can+be+suppressed+by+let-7a+microRNA. assertion.
- assertion asSentence Microbial+infection+promotes+the+formation+of+a+NFkappaB+p50-C%2FEBPbeta+silencer+complex+in+the+regulatory+sequence+of+microRNA+let-7i. assertion.
- assertion asSentence Down-regulation+of+miR-100+is+associated+with+prostate+cancer+metastasis. assertion.
- assertion asSentence miR-107+expression+tends+to+be+lower+relative+to+other+miRNAs+as+Alzheimer%27s+disease+progresses. assertion.
- assertion asSentence miR-107%2C+an+oncogene+miRNA+promoting+gastric+cancer+metastasis+through+down-regulation+of+DICER1. assertion.
- assertion asSentence MicroRNA-10a+is+overexpressed+in+human+pancreatic+cancer+and+involved+in+its+invasiveness. assertion.
- assertion asSentence miR-10b+positively+regulates+the+metastasis+of+nasopharyngeal+carcinoma+%28NPC%29. assertion.
- assertion asSentence Transfection+of+miR-1+into+cell+lines+which+express+low+levels+of+endogenous+miR-1+will+induce+apoptosis. assertion.
- assertion asSentence EVI1+controls+proliferation+in+acute+myeloid+leukemia+through+modulation+of+miR-1-2. assertion.
- assertion asSentence miR-122%2C+a+tumor+suppressor+microRNA+affecting+hepatocellular+carcinoma+intrahepatic+metastasis+by+angiogenesis+suppression%2C+exerts+some+of+its+action+via+regulation+of+ADAM17. assertion.
- assertion asSentence Hepatocellular+carcinoma+has+obvious+alteration+in+the+expression+patterns+of+miR-122+and+miR-224. assertion.
- assertion asSentence miRNA122a-mediated+antigen+silencing+induced+significantly+higher+anti-HBsAg+antibody+titers+allowing+an+up+to+100-fold+vector+dose+reduction. assertion.
- assertion asSentence Modulation+of+the+unfolded+protein+response+is+the+core+of+microRNA-122-involved+sensitivity+to+chemotherapy+in+hepatocellular+carcinoma. assertion.
- assertion asSentence miR-122+enhances+hepatitis+C+virus+fitness+via+targeting+two+sites+in+the+5%27-untranslated+region+of+HCV. assertion.
- assertion asSentence Te+predominant+G0%2FG1+state+of+non-dividing+hepatocytes+in+the+liver+facilitates+high+expression+of+the+HCV+genome+and+stimulation+by+miR-122. assertion.
- assertion asSentence MicroRNA-122+suppresses+cell+proliferation+and+induces+cell+apoptosis+in+hepatocellular+carcinoma+by+directly+targeting+Wnt%2Fbeta-catenin+pathway. assertion.
- assertion asSentence The+miR-124a-controlled+downregulation+of+NFKBIZ+protein+is+involved+in+the+regulation+of+NF-kappaappa+B+activity. assertion.
- assertion asSentence miR-124+inhibits+cell+proliferation+in+gastric+cancer+through+down-regulation+of+SPHK1. assertion.
- assertion asSentence MicroRNAs+miR-125a+and+miR-125b+constitutively+activate+the+NF-kappaB+pathway+by+targeting+the+tumor+necrosis+factor+alpha-induced+protein+3+%28TNFAIP3%2C+A20%29. assertion.
- assertion asSentence Mir-126%2C+a+cell+growth+suppressor%2C+targets+IRS-1. assertion.
- assertion asSentence miR-126+can+downregulate+EGFL7+expression+at+the+protein+level+in+ECV-304+cells. assertion.
- assertion asSentence Downregulation+of+MIR126+is+associated+with+parathyroid+tumors. assertion.
- assertion asSentence Up-regulation+of+let-130a+is+associated+with+periodontitis. assertion.
- assertion asSentence Elevated+levels+of+circulating+miR-133a+in+patients+with+cardiovascular+diseases+originate+mainly+from+the+injured+myocardium. assertion.
- assertion asSentence MicroRNA-141+confers+resistance+to+cisplatin-induced+apoptosis+by+targeting+YAP1+in+human+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence miR-142+inhibits+both+survival+and+growth+pathways+by+directly+targeting+nodal+regulators+p300+and+gp130. assertion.
- assertion asSentence miR-29a+and+miR-142-3p+are+key+regulators+of+normal+myeloid+differentiation+and+their+reduced+expression+is+involved+in+acute+myeloid+leukemia+development. assertion.
- assertion asSentence miR-143+plays+an+important+role+in+prostate+cancer+proliferation%2C+migration+and+chemosensitivity+by+suppressing+KRAS+and+subsequent+inactivation+of+MAPK+pathway. assertion.
- assertion asSentence miR-145+and+miR-133a+function+as+tumour+suppressors+and+directly+regulate+FSCN1+expression+in+bladder+cancer. assertion.
- assertion asSentence MiR-145+exhibits+inhibitory+effects+on+cancer+cell+proliferation. assertion.
- assertion asSentence The+miR-145+plays+important+inhibitory+role+in+breast+cancer+malignancy+by+targeting+N-RAS+and+VEGF-A. assertion.
- assertion asSentence The+natural+genetic+variation+in+pre-miR-146a+affects+the+amount+of+mature+miR-146a%2C+contributes+to+the+genetic+predisposition+to+prostatic+cancer. assertion.
- assertion asSentence miR-146a+promotes+the+differentiation+in+periodontal+ligament+cells+through+the+down-regulation+of+NF-kappaB+signaling. assertion.
- assertion asSentence An+association+between+hsa-mir-146a+genotype+and+tumor+age-of-onset+in+BRCA1%2FBRCA2-negative+familial+breast+and+ovarian+cancer+patients. assertion.
- assertion asSentence Low+expression+of+miR-146a+is+associated+with+gastric+cancer. assertion.
- assertion asSentence P.+gingivalis+LPS+strongly+induces+miRNA-146a+expression+in+THP-1+cells+and+THP-1-derived+macrophages. assertion.
- assertion asSentence Low+miR-148a+is+associated+with+lymph+recurrence+in+squamous+cell+esophageal+carcinoma. assertion.
- assertion asSentence The+expression+of+miR-155+is+up-regulated+in+primary+breast+cancer%2C+especially+in+patients+with+positive+estrogen+and+progesterone+receptor. assertion.
- assertion asSentence The+interleukin+13+%28IL-13%29+pathway+in+human+macrophages+is+modulated+by+microRNA-155+via+direct+targeting+of+interleukin+13+receptor+alpha1+%28IL13Ralpha1%29. assertion.
- assertion asSentence Impairment+of+SKI+expression+is+not+the+leading+mechanism+involved+in+the+growth-suppressive+effect+of+miR-155+found+in+this+malignancy. assertion.
- assertion asSentence Deregulated+miR-155+and+miR-9+play+a+pivotal+role+in+the+pathogenesis+of+Waldenstrom%27s+macroglobulinemia. assertion.
- assertion asSentence The+suppression+of+miR-155+inhibited+BACH1+protein+expression. assertion.
- assertion asSentence The+elevated+expression+levels+of+miR-146a+and+miR-16+are+correlated+to+rheumatoid+arthritis+disease+activity. assertion.
- assertion asSentence Let-7a+and+miR-16+plasma+levels+can+serve+as+noninvasive+prognostic+markers+in+MDS+patients. assertion.
- assertion asSentence MicroRNA-16+and+microRNA-424+regulate+cell-autonomous+angiogenic+functions+in+endothelial+cells+via+targeting+vascular+endothelial+growth+factor+receptor-2+and+fibroblast+growth+factor+receptor-1. assertion.
- assertion asSentence miR-16+targets+SMRT+and+modulates+NF-kappaB-regulated+transactivation+of+the+IL-8+gene. assertion.
- assertion asSentence MiR-16+enhances+G1+phase+arrest+in+mesenchymal+stem+cells+%28MSCs%29%2C+contributing+to+the+differentiation+of+MSCs+toward+myogenic+phenotypes+when+in+a+cardiac+niche. assertion.
- assertion asSentence PTPRO+gene+is+co-regulated+by+both+E2F1+and+miR-17-92. assertion.
- assertion asSentence Increased+expression+of+miR-17-92+cluster+during+colorectal+adenoma+to+adenocarcinoma+progression+is+associated+to+DNA+copy+number+gain+of+miR17-92+locus+on+13q31+and+c-myc+expression. assertion.
- assertion asSentence Differential+expression+of+microRNA+181b+and+microRNA+21+in+hyperplastic+polyps+and+sessile+serrated+adenomas+of+the+colon. assertion.
- assertion asSentence miR-192+and+miR-215+target+thymidylate+synthase+expression+in+colorectal+cancer+cell+lines. assertion.
- assertion asSentence Down-regulation+of+MIRN192+is+associated+with+gastric+carcinoma. assertion.
- assertion asSentence Downregulation+of+miR-195+correlates+with+lymph+node+metastasis+and+colorectal+cancer. assertion.
- assertion asSentence Intra-renal+expression+of+miR-638%2C+miR-198+and+miR-146a+are+differentially+expressed+between+lupus+nephritis+patients+and+normal+controls. assertion.
- assertion asSentence Decreased+expression+of+microRNA-199b+increases+protein+levels+of+SET+%28protein+phosphatase+2A+inhibitor%29+in+human+choriocarcinoma. assertion.
- assertion asSentence Expression+of+miR-17-19b+is+inhibited+in+K562+cell+line+after+5-aza+treatment. assertion.
- assertion asSentence miR-200bc%2F429+cluster+targets+PLCgamma1+and+differentially+regulates+proliferation+and+EGF-driven+invasion+than+miR-200a%2F141+in+breast+cancer. assertion.
- assertion asSentence TGF-beta1-induces+fibrosis+in+vitro+and+inhibits+the+expression+of+miR-200a+and+miR-200b+in+intestinal+epithelial+cells. assertion.
- assertion asSentence miR-200bc%2F429+cluster+targets+PLCgamma1+and+differentially+regulates+proliferation+and+EGF-driven+invasion+than+miR-200a%2F141+in+breast+cancer. assertion.
- assertion asSentence TGF-beta1-induces+fibrosis+in+vitro+and+inhibits+the+expression+of+miR-200a+and+miR-200b+in+intestinal+epithelial+cells. assertion.
- assertion asSentence miR-200+family+controls+beta-tubulin+III+expression+and+is+associated+with+paclitaxel-based+treatment+response+and+progression-free+survival+in+ovarian+cancer. assertion.
- assertion asSentence The+ZEB1%2FmiR-200+feedback+loop+controls+Notch+signalling+in+cancer+cells. assertion.
- assertion asSentence Loss+of+miR-200c+is+associated+with+colon+cancer. assertion.
- assertion asSentence miRNA-205+is+a+glioma-specific+tumor+suppressor+which+targets+VEGF-A. assertion.
- assertion asSentence Downregulation+of+miR-1%2C+-206+and+-29+stabilizes+the+expression+of+PAX3+and+CCND2+in+both+embryonal+and+alveolar+rhabdomyosarcoma. assertion.
- assertion asSentence miR-21+is+upregulated+in+papillary+thyroid+carcinoma. assertion.
- assertion asSentence miR-21+links+hypoxia+with+cell+cycle+regulation+and+is+deleted+in+human+epithelial+ovarian+cancer. assertion.
- assertion asSentence miR-21+represents+a+promising+target+for+therapeutic+manipulation+to+increase+the+efficacy+of+chemotherapeutic+agents+in+treating+glioblastoma. assertion.
- assertion asSentence miR-21+regulates+PDCD4+expression+after+LPS+stimulation. assertion.
- assertion asSentence miR-21+is+not+a+central+player+in+the+onset+of+prostate+cancer. assertion.
- assertion asSentence Tumor+suppressor+phosphatase+and+tensin+homolog+PTEN+is+negatively+regulated+by+miR-21+at+post-transcriptional+level+via+binding+to+3%27-untranslated+region+%28UTR%29+of+PTEN+mRNA+in+non-small+cell+lung+cancer+cells. assertion.
- assertion asSentence Overexpression+of+miR-21+in+human+circulating+angiogenic+progenitor+cells+impairs+migratory+capacity. assertion.
- assertion asSentence The+mechanism+of+miR-21+antineoplastic+drug+resistance+involves+the+PI3K%2FAkt+pathway+and+changes+following+PTEN+protein+expression. assertion.
- assertion asSentence The+level+of+miR-21+correlates+with+the+tumor+differentiation+and+nodal+status+by+ISH. assertion.
- assertion asSentence miR-21+functionally+interacts+with+the+3%27UTR+of+CCL20+mRNA. assertion.
- assertion asSentence Increased+circulating+miR-21c+is+associated+with+malignant+pleural+mesothelioma. assertion.
- assertion asSentence Expression+of+HB-EGF+is+regulated+by+miR-212+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence Decreased+microRNA-214+levels+in+breast+cancer+cells+coincides+with+increased+cell+proliferation%2C+invasion+and+accumulation+of+the+Polycomb+Ezh2+methyltransferase. assertion.