Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence miR-214%2C+miR-150%2C+miR-146a+and+miR-125b+targeted+HTT. assertion.
- assertion asSentence In+gastric+cancer%2C+both+microRNA-192+and+-215+are+overexpressed+in+vivo+and+exert+cell+growth+and+migration-promoting+effects+in+vitro. assertion.
- assertion asSentence Loss+of+miR-215+is+associated+with+colon+cancer. assertion.
- assertion asSentence MicroRNA-217+is+found+to+be+an+endogenous+inhibitor+of+silent+information+regulator+1+in+endothelial+cell+senescence. assertion.
- assertion asSentence Frequently+downregulated+miR-217+can+regulate+KRAS+and+function+as+a+tumor+suppressor+in+pancreatic+ductal+adenocarcinoma+%28PDAC%29. assertion.
- assertion asSentence MIR218-1+and+MIR218-2+are+deleted+and+downregulated+in+lung+squamous+cell+carcinoma. assertion.
- assertion asSentence miR-218+is+involved+in+the+invasive+behavior+of+glioblastoma+cells+by+targeting+LEF1+and+blocking+the+invasive+axis. assertion.
- assertion asSentence miR-22+acts+as+a+tumor+suppressor+through+direct+repression+of+MYCBP+expression+and+subsequent+reduction+of+oncogenic+c-Myc+activities. assertion.
- assertion asSentence Up-regulation+of+miR-221+expression+is+an+accurate+way+to+differentiate+leiomyosarcoma+from+benign+metastasizing+leiomyoma. assertion.
- assertion asSentence Downregulation+of+miR-221+is+associated+with+prostate+tumor+progression+and+recurrence. assertion.
- assertion asSentence Down-regulation+of+miR-221+correlates+with+pronounced+Kit+expression+and+is+associated+with+gastrointestinal+stromal+tumors. assertion.
- assertion asSentence miR-221%2F222+targeting+of+trichorhinophalangeal+1+%28TRPS1%29+promotes+epithelial-to-mesenchymal+transition+in+breast+cancer. assertion.
- assertion asSentence Increased+expression+of+MIR222+is+associated+with+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence MIR222+negatively+regulates+expression+of+CDKN1B+%28p27%29+and+CDKN1C+%28p57%29+in+ovarian+surface+epithelium+and+down-regulated+in+ovarian+carcinomas. assertion.
- assertion asSentence The+suppression+of+miR-222+plays+a+crucial+role+in+the+protection+against+apoptosis+induced+by+ER+stress+in+HCC+cells. assertion.
- assertion asSentence miR-223+expression+is+responsive+to+acute+alterations+in+cyclin+E+regulation+by+the+Fbw7+pathway. assertion.
- assertion asSentence miR-223+is+overexpressed+only+in+metastatic+gastric+cancer+cells+and+stimulated+nonmetastatic+gastric+cancer+cells+migration+and+invasion. assertion.
- assertion asSentence MicroRNA-23b+plays+a+role+in+pulsatile-flow-regulation+of+retinoblastoma-protein+phosphorylation+and+endothelial+cell+growth. assertion.
- assertion asSentence Inhibition+of+miR-25+in+cytokine-stimulated+ASM+cells+up-regulates+KLF4+expression+via+a+post-transcriptional+mechanism. assertion.
- assertion asSentence miR-2b+is+downregulated+in+melanoma+cells+exposed+to+a+human+embryonic+stem+cell+environment. assertion.
- assertion asSentence miR-29a+and+miR-142-3p+are+key+regulators+of+normal+myeloid+differentiation+and+their+reduced+expression+is+involved+in+acute+myeloid+leukemia+development. assertion.
- assertion asSentence Hsa-mir-299-5p+targets+OPN. assertion.
- assertion asSentence Hsa-miR-299-5p+emerged+as+having+a+role+in+controlling+CD34%2B+progenitor+fate%2C+grown+in+multilineage+culture+conditions. assertion.
- assertion asSentence microRNA-29b+contributes+to+pre-eclampsia+through+its+effects+on+apoptosis%2C+invasion+and+angiogenesis+of+trophoblast+cells. assertion.
- assertion asSentence Hsa-miR-302b+and+hsa-miR-372+regulate+expression+of+a+number+of+targets+that+influence+reprogramming+of+human+somatic+cells. assertion.
- assertion asSentence MiR-30+family+are+involved+in+the+BDNF+gene+expression+during+late+maturation+and+aging+of+human+prefrontal+cortex. assertion.
- assertion asSentence Mir-30+reduction+maintains+self-renewal+and+inhibits+apoptosis+in+breast+tumor-initiating+cells. assertion.
- assertion asSentence miR-30+family+microRNAs+form+a+part+of+the+regulatory+signaling+events+involved+in+cellular+response+of+pancreatic+epithelial+cells+during+mesenchymal+transition. assertion.
- assertion asSentence Frequent+homozygous+losses+of+miR-31+is+associated+with+urothelial+carcinomas. assertion.
- assertion asSentence miR-31+contributes+to+the+development+of+head+and+neck+squamous+cell+carcinoma+by+impeding+FIH+to+activate+HIF+under+normoxic+conditions. assertion.
- assertion asSentence MiR-31+expression+levels+increase+with+disease+progression+and+accurately+discriminates+between+distinct+pathological+entities+that+coexist+in+inflammatory+bowel+disease. assertion.
- assertion asSentence The+downregulation+of+miR-205+and+miR-31+has+an+important+role+in+apoptosis+resistance+in+advanced+prostate+cancer. assertion.
- assertion asSentence Ectopic+expression+of+miR-31+inhibited+migration+and+invasion+ability+of+U251+glioma+cells. assertion.
- assertion asSentence miR-34a+methylation+is+preferentially+hypermethylated+in+NHL%2C+in+particular+NK%2FT-cell+lymphoma%2C+in+a+tumor-specific+manner. assertion.
- assertion asSentence miR-34a+tempers+the+proliferative+and+pro-survival+effect+of+growth+factor+stimulation+by+interfering+with+growth+factor+signal+transduction+and+downstream+pathways+required+for+cell+division. assertion.
- assertion asSentence EBV+LMP1+induces+miR-34a+expression+in+an+NF-kappaB-dependent+manner. assertion.
- assertion asSentence MIR34A+contributes+to+the+impaired+function+of+bone+marrow+derived+mononuclear+cells+from+patients+with+cardiovascular+disease. assertion.
- assertion asSentence Loss+of+MIRN34B+is+associated+with+cell+invasion+and+motility+in+melanoma. assertion.
- assertion asSentence High+microRNA-34b+is+associated+with+small-cell+lung+cancer. assertion.
- assertion asSentence miR-17-92+and+its+target+CTGF+mediate+effects+of+differentiation-promoting+treatment+on+glioblastoma+cells+through+multiple+regulatory+pathways. assertion.
- assertion asSentence High+miR-17-92+is+associated+with+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence Aberrnntly+expressed+Pim-3+can+cause+autonomous+cell+proliferation+or+prevent+apoptosis+in+hepatoma+cell+lines. assertion.
- assertion asSentence Pim3+cooperates+with+other+Pim+kinases+in+supporting+viability+of+Myc-induced+B-cell+lymphomas. assertion.
- assertion asSentence UV-induced+eIF2alpha+phosphorylation+by+activation+of+both+PERK+and+GCN2+via+oxidative+stress+and+l-arginine+starvation+signaling+pathways. assertion.
- assertion asSentence Changes+in+translational+control+of+mitochondrial+proteins+are+signaled+by+the+activation+of+AMPK+%28AMP-activated+protein+kinase%29+and+GCN2%2C+leading+also+to+the+activation+of+autophagy. assertion.
- assertion asSentence No+association+between+iNOS+Ser+608+Leu+polymorphism+and+risk+of+Barrett%27s+esophagus+or+reflux+esophagitis. assertion.
- assertion asSentence Knockdown+of+autophagy-related+protein+beclin+1+%28BCN1%29+or+autophagy-related+protein+7+%28ATG7%29+in+immortalized+human+hepatocytes+%28IHHs%29+inhibits+hepatitis+C+virus+growth. assertion.
- assertion asSentence Human+cytomegalovirus+protein+TRS1+inhibits+autophagy+via+its+interaction+with+Beclin+1. assertion.
- assertion asSentence Aberrant+expression+and+functional+significance+ofthe+miR-1%2FmiR-133a+and+miR-206%2FmiR-133b+clusters+in+human+cancers. assertion.
- assertion asSentence miR-330+induces+apoptosis+in+prostate+cancer+cells+through+E2F1-mediated+suppression+of+Akt+phosphorylation. assertion.
- assertion asSentence miR-335+downregulation+is+critical+for+the+acquisition+of+reparative+MSC+phenotypes. assertion.
- assertion asSentence Transcriptional+activation+of+apoptosis-associated+tyrosine+kinase+%28AATK%29%2C+also+generates+miR-338+from+an+AATK+gene+intron+that+silences+a+family+of+mRNAs+whose+protein+products+are+negative+regulators+of+neuronal+differentiation. assertion.
- assertion asSentence Hsa-miR-302b+and+hsa-miR-372+regulate+expression+of+a+number+of+targets+that+influence+reprogramming+of+human+somatic+cells. assertion.
- assertion asSentence Crystal+structure+of+PRY-SPRY+domain+of+human+TRIM72. assertion.
- assertion asSentence EID3+acts+as+an+inhibitor+of+CBP%2Fp300-dependent+transcription+in+a+tissue-specific+manner. assertion.
- assertion asSentence miR-375+is+an+important+regulator+of+YAP+oncogene+playing+the+role+in+hepatocellular+carcinoma+development. assertion.
- assertion asSentence The+miR-383+functions+as+a+negative+regulator+of+proliferation+by+targeting+IRF1. assertion.
- assertion asSentence MicroRNA-16+and+microRNA-424+regulate+cell-autonomous+angiogenic+functions+in+endothelial+cells+via+targeting+vascular+endothelial+growth+factor+receptor-2+and+fibroblast+growth+factor+receptor-1. assertion.
- assertion asSentence VEGF+expression+in+breast+cancer+cells+is+mediated+by+HIF-1+and+STAT3+in+a+miR-20b-dependent+manner. assertion.
- assertion asSentence HDAC6+3%27-UTR+variant+suppressed+hsa-miR-433-mediated+post-transcriptional+regulation+causing+the+overexpression+of+HDAC6. assertion.
- assertion asSentence Loss+of+miR+488+is+associated+with+prostate+carcinoma. assertion.
- assertion asSentence MIRN499+polymorphism+is+associated+with+hepatocellular+carcinoma. assertion.
- assertion asSentence MIRN503+is+associated+with+metastatic+function+in+hepatocellular+cancer. assertion.
- assertion asSentence In+a+Chinese+Han+population+a+higher+copy+number+of+DEFA1%2FDEFA3+is+significantly+associated+with+the+risk+of+severe+sepsis. assertion.
- assertion asSentence Overexpression+of+microRNA+486+is+associated+with+highly+invasive+and+metastatic+pancreatic+ductal+adenocarcinomas. assertion.
- assertion asSentence ECSM2+is+involved+in+cell-shape+changes+and+actin+cytoskeletal+rearrangement%2C+suppresses+tyrosine+phosphorylation+signaling+and+ECSM2+can+cross-talk+with+EGFR+to+attenuate+the+EGF-induced+cell+migration. assertion.
- assertion asSentence ECSM2+modulated+bFGF-directed+endothelial+cell+motility+via+the+FGF+receptor+%28FGFR%29-extracellular+regulated+kinase+%28ERK%29-focal+adhesion+kinase+%28FAK%29+pathway. assertion.
- assertion asSentence TDP-43+is+a+common+pathologic+substrate+linking+a+variety+of+distinct+patterns+of+FTLD-U+pathology+caused+by+different+genetic+alterations. assertion.
- assertion asSentence Association+of+severity+of+spinal+muscular+atrophy+with+the+loss+of+NAIP+gene. assertion.
- assertion asSentence Overweight+and+obese+adults+demonstrate+increased+vascular+endothelial+expression+of+NAD%28P%29H+oxidase-p47%28phox%29+linked+to+oxidative+stress. assertion.
- assertion asSentence p40%28phox%29+translocates+p67%28phox%29+to+the+region+of+the+cytochrome+and+subsequently+switches+the+oxidase+to+an+activated+state+dependent+upon+PtdIns%283%29P+and+SH3+domain+engagement. assertion.
- assertion asSentence Protein+kinase+C-dependent+phosphorylation+of+p47%28phox%29+is+essential+for+platelet+derived+growth+factor-stimulated+reactive+oxygen+species+generation+and+proliferation+in+human+vascular+endothelium. assertion.
- assertion asSentence Ezh2+competes+with+HDAC1+in+binding+to+pRb2%2Fp130%2C+disrupting+their+occupancy+on+the+cyclin+A+promoter. assertion.
- assertion asSentence There+is+an+increased+expression+of+NADPH+oxidase+p47%28-PHOX%29+and+p67%28-PHOX%29+factor+in+idiopathic+pulmonary+fibrosis+patients. assertion.
- assertion asSentence NF-kappaB+is+necessary+for+CYBB+and+NCF1+gene+expression+and+activation+of+the+phagocyte+NADPH+oxidase+normal+and+anhidrotic+ectodermal+dysplasia+leukocytes. assertion.
- assertion asSentence The+direct+interaction+of+PI3Kgamma+with+PKCalpha+forms+a+discrete+regulatory+module+of+N-formylmethionyl-leucyl-phenylalanine-dependent+reactive+oxygen+species+production+in+neutrophils. assertion.
- assertion asSentence p47phox+molecular+activation+for+assembly+of+the+neutrophil+NADPH+oxidase+complex. assertion.
- assertion asSentence Human+SP-A+induces+the+secretion+of+immunoregulatory+molecules+such+as+TNF-alpha+and+IL-10+by+two+well-defined+populations+of+human+and+murine+macrophages. assertion.
- assertion asSentence SP-A+enhances+phagocytosis+of+apoptotic+cells+by+human+and+murine+alveolar+macrophages+in+vitro%2C+independent+of+the+apoptotic+cell+type. assertion.
- assertion asSentence Genetic+polymorphism+in+surfactant+protein+A+is+associated+with+the+development+of+chronic+obstructive+pulmonary+disease+in+the+Chinese+Hans. assertion.
- assertion asSentence hSP-A1+5%27-UTR+splice+variants+play+an+important+role+in+both+SP-A+translation+and+mRNA+stability. assertion.
- assertion asSentence Surfactant+protein+A+%28SP-A%29%2C+expressed+consistently+less+in+bronchiolitis+obliterans+syndrome+patients+than+in+stable+lung+transplant+recipients. assertion.
- assertion asSentence Lung-derived+SP-A+protein+is+associated+with+altered+glucose+tolerance+and+insulin+resistance+in+164+nonsmoking+men. assertion.
- assertion asSentence Surfactant+protein+A+is+defective+in+abrogating+inflammation+in+asthma. assertion.
- assertion asSentence Human+ZG16p+recognizes+pathogenic+fungi+through+non-self+polyvalent+mannose+in+the+digestive+system. assertion.
- assertion asSentence High+serum+microRNA+574+expression+is+associated+with+early-stage+non-small+cell+lung+cancer. assertion.
- assertion asSentence MicroRNA-602+plays+a+pro-carcinogenic+role+in+HBV-related+hepatocarcinogenesis+by+inhibiting+RASSF1A. assertion.
- assertion asSentence Intra-renal+expression+of+miR-638%2C+miR-198+and+miR-146a+are+differentially+expressed+between+lupus+nephritis+patients+and+normal+controls. assertion.
- assertion asSentence The+spinocerebellar+ataxia+type+8+is+caused+by+Trinucleotide+Repeat+Expansion+in+ataxin+8+protein. assertion.
- assertion asSentence SNORD116-19%2C+located+in+a+cluster+of+imprinted+genes+on+chromosome+15q11%2C+is+imprinted%2C+with+preferential+expression+from+the+paternal+allele. assertion.
- assertion asSentence Structure+and+biosynthesis+of+human+salivary+mucins. assertion.
- assertion asSentence E2%2C+a+sex+hormone%2C+stimulates+MUC5B+gene+overexpression+by+interaction+with+estrogen+receptor+alpha+%28ERalpha%29+and+by+acting+through+extracellular+signal-regulated+kinase+1%2F2+%28ERK1%2F2%29-mitogen-activated+protein+kinase+%28MAPK%29. assertion.
- assertion asSentence Val64Ile+polymorphism+in+the+C-C+chemokine+receptor+2+is+associated+with+reduced+coronary+artery+calcification. assertion.
- assertion asSentence Polymorphism+is+associated+with+myocardial+infarct. assertion.
- assertion asSentence AGE-LDL+can+increase+CCR2+expression+in+macrophages+and+stimulate+the+chemotactic+response+elicited+by+MCP-1. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+in+monocyte+chemoattractant+protein-1+and+its+receptor+act+synergistically+to+increase+the+risk+of+carotid+atherosclerosis. assertion.
- assertion asSentence CC+chemokine+receptor+2+and+IL-8+play+roles+in+the+pathogenesis+and+resolution+of+acute+lung+injury+%28ALI%29+and+acute+respiratory+distress+syndrome+%28ARDS%29. assertion.
- assertion asSentence CCL2+secreted+by+tumor+cells+and+CCR2+receptors+on+cytotoxic+T+lymphocytes+%28CTLs%29+are+involved+in+migration+of+CTLs+towards+tumor. assertion.
- assertion asSentence The+CCR2+V64I+allele+has+not+been+found+any+association+with+coronary+artery+disease. assertion.
- assertion asSentence CCL2-CCR2+and+CXCL1-CXCR1+signaling+are+involved+in+age+related+macular+degeneration. assertion.