Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence As+the+inner+cell+mass+forms+the+epiblast%2C+SSEA1+is+lost+and+VIMENTIN+is+lost+and+re-expressed. assertion.
- assertion asSentence Retinal+ischemia-reperfusion+alters+expression+of+mitogen-activated+protein+kinases%2C+particularly+ERK1%2F2%2C+in+the+neuroretina+and+retinal+arteries. assertion.
- assertion asSentence Cloning+and+expression+of+interleukin-17. assertion.
- assertion asSentence The+Chinese+Rongchang+pig+has+the+dominant+black+E%28D1%29+allele+at+the+melanocortin+1+receptor+%28MC1R%29+locus. assertion.
- assertion asSentence Breed+specific+mutations+of+the+MC1+receptor+in+an+Italian+breed+of+swine. assertion.
- assertion asSentence Mucosae+associated-epithelial+chemokine+%28MEC%2FCCL28%29+cloned+from+porcine+salivary+gland+and+colon+tissues+consisted+of+an+open+reading+frame+%28ORF%29+of+384-bp+coding+for+127+amino-acids+protein+with+22+residues+signal+sequence. assertion.
- assertion asSentence Bid+and+Bax+are+signal+transduction+factors+in+granulosa+cells+and+play+proapoptotic+roles. assertion.
- assertion asSentence Existence+of+a+polymorphism+in+the+ENO3+gene+that+it+is+associated+with+fat+percentage%2C+average+backfat+thickness%2C+meat+marbling+and+intramuscular+fat+in+two+different+populations. assertion.
- assertion asSentence The+phylogenetic+trees+reveal+that+porcine+Gna11%2C+is+evolutionarily+close+to+the+human+homolog. assertion.
- assertion asSentence Treatment+with+endogenous+anti-inflammatory+protein+netrin-1+reduces+pulmonary+inflammation+during+the+initial+stages+of+acute+lung+injury. assertion.
- assertion asSentence The+plasminogen%2Fplasminogen+activator%2Fplasmin+system+is+activated+during+gamete+interaction+and+regulates+the+sperm+entry+into+the+oocyte. assertion.
- assertion asSentence Differential+expression+of+RANKL+ratio+regulates+regional+variation+of+periosteal+activity+at+the+mandibular+ramus. assertion.
- assertion asSentence Translation+initiation+factor+eIF4E+is+phosphorylated+during+in+vitro+maturation+of+pig+oocytes+with+a+maximum+in+metaphase+II+stage+oocytes. assertion.
- assertion asSentence The+phylogenetic+trees+reveal+that+porcine+Gna14%2C+is+evolutionarily+close+to+the+human+homolog. assertion.
- assertion asSentence Regional+variation+of+periosteal+activity+at+the+mandibular+ramus+is+regulated+by+differential+expression+of+osteoprotegerin. assertion.
- assertion asSentence Patatin-like+phospholipase+domain+containing+2+gene+%28PNPLA2%29+is+assiged+to+chromosome+2+in+pigs. assertion.
- assertion asSentence Mechanical+injury+of+vascular+smooth+muscle+up-regulated+keratin+18. assertion.
- assertion asSentence Role+of+Y118+paxillin+phosphorylation+and+stimulated+actin+polymerization+in+carotid+artery+contraction. assertion.
- assertion asSentence Foot-and-mouth+disease+virus+3C+protease+cleaves+NEMO+to+impair+innate+immune+signaling. assertion.
- assertion asSentence Polymorphisms+within+the+CYP2C18+gene+are+not+a+significant+cause+of+high+skatole+levels. assertion.
- assertion asSentence A+peak+in+Reelin+mRNA+and+protein+expression+is+present+in+the+pig+embryonic+brain+during+the+period+of+major+neurogenesis+and+neuronal+migration. assertion.
- assertion asSentence SAF-1+transcription+factor+and+MMP-14+coexpress+in+the+cells+of+atherosclerotic+plaques. assertion.
- assertion asSentence Different+genotypes+of+the+CMYA4+gene+are+significantly+associated+with+the+backfat+thickness+of+the+area+between+sixth+and+seventh+ribs+%28p+%3C+0.05%29+and+backfat+thickness+at+the+shoulder+%28p+%3C+0.05%29. assertion.
- assertion asSentence Viral+non-structural+protein+1+suppressed+host+TNF-alpha+promoter+by+inhibiting+NF-kappaB+and+Sp1+promoter+binding+activity. assertion.
- assertion asSentence The+complete+cDNA+sequence+of+CLK1+is+1680+bp%2C+containing+a+414+bp+ORF+encoding+a+deduced+protein+of+137+amino+acids. assertion.
- assertion asSentence AMPK+functions+to+inhibit+IGF-I-stimulated+PI3K+pathway+activation+through+stimulation+of+IRS-1+serine+794+phosphorylation. assertion.
- assertion asSentence mRNA+and+protein+expression+of+FGFR-1%2C+FGFR-2+in+the+porcine+umbilical+cord+during+pregnancy. assertion.
- assertion asSentence 20-HETE+activates+the+Raf%2FMEK%2FERK+pathway+in+renal+epithelial+cells+through+an+EGFR-+and+c-Src-dependent+mechanism. assertion.
- assertion asSentence The+porcine+chloride+channel+calcium-activated+family+member+pCLCA4a+mirrors+lung+expression+of+the+human+hCLCA4. assertion.
- assertion asSentence Retinal+ischemia-reperfusion+alters+expression+of+mitogen-activated+protein+kinases%2C+particularly+ERK1%2F2%2C+in+the+neuroretina+and+retinal+arteries. assertion.
- assertion asSentence Regional+variation+of+periosteal+activity+at+the+mandibular+ramus+is+regulated+by+differential+induction+of+BMP2. assertion.
- assertion asSentence The+structure-bound+sperm-specific+enzymes%2C+GAPDH-S+and+pyruvate+kinase%28PK-S%29%2C+appeared+only+late+in+spermatogenesis+simultaneously+with+the+development+of+the+structures+to+which+they+are+bound. assertion.
- assertion asSentence Pgam2+gene+plays+an+important+role+in+muscle+growth+and+development. assertion.
- assertion asSentence Knock-down+of+XBP1+enhanced+endoplasmic+reticulum+stress-mediated+cell+death+in+porcine+embryonic+fibroblasts. assertion.
- assertion asSentence 20-HETE+activates+the+Raf%2FMEK%2FERK+pathway+in+renal+epithelial+cells+through+an+EGFR-+and+c-Src-dependent+mechanism. assertion.
- assertion asSentence Neuropilin-1+is+essential+for+enhanced+VEGF%28165%29-mediated+vasodilatation+in+collateral-dependent+coronary+arterioles+of+exercise-trained+pigs. assertion.
- assertion asSentence The+NAT9+gene+can+be+an+useful+candidate+gene+in+selection+for+increasing+litter+size+in+pigs. assertion.
- assertion asSentence Downregulation+of+miR-199a+derepresses+hypoxia-inducible+factor-1alpha+and+Sirtuin+1+and+recapitulates+hypoxia+preconditioning+in+cardiac+myocytes. assertion.
- assertion asSentence The+tight+junction+protein+ZO-2+is+involved+in+regulation+of+vascular+smooth+muscle+cells+growth+control+upon+vascular+injury+that+is+mediated+by+the+transcription+factor+Stat1. assertion.
- assertion asSentence Sympathetic+alpha3beta2-nAChRs+mediate+basilar+artery+neurogenic+nitrergic+vasodilation+in+swine. assertion.
- assertion asSentence The+D6+blastocyst+expressed+high+levels+of+TERF1. assertion.
- assertion asSentence Cx43+expression+and+distribution+are+disrupted+by+ischemia%2C+recovered+by+the+well+reperfused+regions+and+further+disrupted+by+no-reflow. assertion.
- assertion asSentence AT1+receptors+are+positively+coupled+to+the+proliferative+response+of+vascular+smooth+muscle+cells+to+angiotensin+II. assertion.
- assertion asSentence Intracoronary+delivery+of+DNAzymes+targeting+human+EGR-1+reduces+infarct+size+following+myocardial+ischaemia+reperfusion. assertion.
- assertion asSentence Calcitonin+is+a+regulator+of+the+25-hydroxyvitamin+D3+1alpha-hydroxylase+gene. assertion.
- assertion asSentence Similar+to+human+and+mouse%2C+NAP1L5+is+a+paternally+expressed+and+maternally+imprinted+gene+in+porcine+placenta. assertion.
- assertion asSentence Coexpression+of+the+2+titin+isoforms+in+large+mammals+allows+longer+sarcomere+lengths+without+the+development+of+excessive+diastolic+tension. assertion.
- assertion asSentence Examination+of+a+dipalmitoylphosphatidylcholine+membrane-bound+prothrombin+1+fragment+reveals+another+well-defined+carboxyglutamic+acid+%28Gla+domain%29-binding+site+for+phosphatidylserine. assertion.
- assertion asSentence CD9+present+on+bovine+matured+oocytes+is+involved+in+sperm-oocyte+interaction+during+fertilization. assertion.
- assertion asSentence CRH+is+a+promising+candidate+gene+for+a+concordant+QTL+related+to+lipid+metabolism+in+mammals. assertion.
- assertion asSentence OTR1%2C+OTX2+and+CRX+act+as+positive+modulators+of+the+BEST1+promoter+in+the+retinal+pigment+epithelium. assertion.
- assertion asSentence Leptin+modulation+of+lymphocytic+growth+hormone+plays+a+role+in+the+regulation+of+immune+response+during+pregnancy. assertion.
- assertion asSentence Food+deprivation-induced+decrease+in+circulating+IGF-I+in+steers+is+associated+with+decrease+in+expression+of+different+IGF-I+mRNA+variants+and+specific+decrease+in+expression+of+growth+hormone+receptor+mRNA+variants+1C3+and+1A+in+liver. assertion.
- assertion asSentence Insulin+regulates+the+efficiency+of+GH+signaling+in+liver+and+adipose+tissue+of+dairy+cows+by+acting+as+a+rheostat+of+GHR+synthesis. assertion.
- assertion asSentence The+pressure-insensitivity+of+mature+insulin+fibrils+demonstrates+that+an+extensive+hydrogen+bonding+network+and+optimized+side-chain+packing+are+crucial+for+their+stability. assertion.
- assertion asSentence The+gas-phase+basicity+of+the+peptide+charge+state+and+ligand+drive+the+type+of+complexes+bovine+insulin+forms+with+various+amino+sugars%2C+irrespective+of+their+structural+differences. assertion.
- assertion asSentence Bradykinin%2C+together+with+its+precursor+and+tissue+kallikrein%2C+is+continuously+released+into+the+vasculature+of+the+isolated%2C+perfused%2C+lactating+bovine+udder. assertion.
- assertion asSentence Despite+being+overexpressed%2C+the+molecular+properties+of+alpha-crystallins+are+disrupted+by+diabetes+and+contribute+to+the+loss+of+neuroprotective+function. assertion.
- assertion asSentence SCF%28FBX4-alphaB+crystallin%29+is+an+E3+ubiquitin+ligase+that+promotes+ubiquitin-dependent+degradation+of+Thr286-phosphorylated+cyclin+D1. assertion.
- assertion asSentence Tissue-specific+promoter+activity+can+be+modulated+by+changing+as+few+as+two+apparently+neutral+nucleotides+in+the+mouse+alphaB-crystallin+enhancer+region. assertion.
- assertion asSentence CRYAB+is+a+potent+negative+regulator+acting+as+a+brake+on+several+inflammatory+pathways+in+both+the+immune+system+and+central+nervous+system+%28CNS%29. assertion.
- assertion asSentence Decreased+gene+expression+of+Cryaa+and+Cryab+in+the+lens+is+associated+with+the+development+of+cataract+in+OXYS+rats. assertion.
- assertion asSentence Lysine+269+is+essential+for+cyclin+D1+ubiquitylation+by+the+SCF%28Fbx4%2FalphaB-crystallin%29+ligase. assertion.
- assertion asSentence Therapeutic+effects+of+systemic+administration+of+chaperone+alphaB-crystallin+associated+with+binding+proinflammatory+plasma+proteins. assertion.
- assertion asSentence A+1-bp+deletion+in+gammaC-crystallin+leads+to+cataract. assertion.
- assertion asSentence Crygf%28Rop%29+is+the+first+mutation+affecting+the+Crygf+gene. assertion.
- assertion asSentence Disruption+of+the+CRYM+gene+decreases+T%283%29+concentrations+in+tissues+and+serum+without+alteration+of+peripheral+T%283%29+action+in+vivo. assertion.
- assertion asSentence During+renal+inflammation+CSF-1+mediates+macrophage+recruitment%2C+proliferation%2C+activation%2C+and%2C+in+turn%2C+tubular+epithelial+cell+apoptosis. assertion.
- assertion asSentence Ly-6G-positive+granulocytes+express+CSF-1R+after+overnight+culture+and+can+subsequently+differentiate+to+form+F4%2F80-positive+macrophages+in+response+to+CSF-1. assertion.
- assertion asSentence Macrophage+colony-stimulating+factor+does+not+play+a+role+in+macrophage+recruitment+in+the+adipose+tissue+of+obese+mice. assertion.
- assertion asSentence Transcriptional+effects+of+colony-stimulating+factor-1+in+mouse+macrophages. assertion.
- assertion asSentence PI3K%2FAkt+signal+cooperates+with+smad1%2F5+in+BMP2-induced+CSF-1+expression+and+osteoclast+differentiation. assertion.
- assertion asSentence The+different+spatiotemporal+expression+of+IL-34+and+CSF-1+allows+for+complementary+activation+of+the+CSF-1R+in+developing+and+adult+tissues. assertion.
- assertion asSentence GM-CSF-treated+macrophages+reveal+a+relationship+between+histone+deacetylase+complexes+and+STAT5+in+the+regulation+of+gene+expression. assertion.
- assertion asSentence Concerted+action+of+GM-CSF+and+Flt3-ligand+on+dendritic+cells+homeostasis+in+vivo. assertion.
- assertion asSentence Recombinant+mouse+GM-CSF+in+the+lung+rescues+mice+from+lethal+pneumococcal+pneumonia+via+adenoviral-mediated+gene+transfer+of+GM-CSF+either+14+or+even+28+days+before+infection. assertion.
- assertion asSentence AEC+in+standard+cultures+constitutively+express+abundant+GM-CSF. assertion.
- assertion asSentence GM-CSFRalpha+levels+peaked+between+E13+and+E15+in+the+brain. assertion.
- assertion asSentence Ligand-binding+and+receptor+activation+are+not+critically+dependent+on+individual+N-glycosylation+sites+within+the+IL-3-+and+IL-5-receptor+common+beta-subunit. assertion.
- assertion asSentence Bcr-Abl+oncoprotein+requires+the+IL-3+receptor%2FJak2%2FStat5+pathways+for+oncogenic+transformation+of+NIH+3T3+fibroblasts. assertion.
- assertion asSentence G-CSF+is+a+direct+transcriptional+target+of+JunB+and+mutant+epidermis+releases+large+amounts+of+G-CSF+that+reach+high+systemic+levels+and+cause+skin+ulcerations%2C+myeloproliferative+disease+and+low+bone+mass. assertion.
- assertion asSentence COOH-terminal+truncation+mutants+of+G-CSF-R%2C+found+in+severe+congenital+neutropenia%2C+lack+internalization+motifs+and+are+completely+defective+in+both+spontaneous+and+ligand-induced+internalization. assertion.
- assertion asSentence Csk+is+required+both+for+angiogenic+sprouting+and+vascular+remodeling. assertion.
- assertion asSentence Neutrophil+transendothelial+migration+induced+by+septic+alveolar+macrophages+is+dependent+on+the+generation+of+superoxide+in+endothelial+cells+via+the+c-Src+kinase%2FNADPH+oxidase+signaling+pathway. assertion.
- assertion asSentence Glucose+6-phosphate+dehydrogenase+is+regulated+through+c-Src-mediated+tyrosine+phosphorylation+in+endothelial+cells. assertion.
- assertion asSentence In+vitro+expression+of+recombinant+basement+membrane-mediated+beta-casein+gene+can+be+controlled+pharmacologically+by+histone+deacetylase+inhibitors+or+by+overexpression+of+a+histone+acetylase+enzyme. assertion.
- assertion asSentence CSN3+and+CSN5+are+involved+in+oocyte+meiosis+by+regulating+degradation+of+Cyclin+B1+and+Securin+via+APC%2FC. assertion.
- assertion asSentence CK2+regulates+NKX3-1+in+prostate+cells. assertion.
- assertion asSentence Lack+of+DNA-PKcs+is+accompanied+by+an+increase+in+the+protein+level+of+one+of+the+catalytic+isozymes+of+protein+kinase+CK2%2C+i.e.%2C+CK2alpha%27+and+a+concomitant+increase+in+CK2+activity. assertion.
- assertion asSentence A+role+for+Hsp40+crosstalk+with+CSPalpha+in+neuroprotection. assertion.
- assertion asSentence Early+postnatal+NG2-expressing+%28NG2%2B%29+progenitor+cells+located+in+the+SVZ+self-renew+in+vitro+and+display+phenotypic+features+of+transit-amplifier+type+C-like+multipotent+cells. assertion.
- assertion asSentence Robust+activation+of+calcium+ion-permeable+AMPA+receptors+in+NG2-expressing+cells+expands+the+influence+of+the+olivocerebellar+projection+to+this+abundant+class+of+glial+progenitors. assertion.
- assertion asSentence Versican+G3+domain+enhanced+tumor+cell+resistance+to+apoptosis+when+cultured+in+serum+free+medium%2C+Doxorubicin%2C+or+Epirubicin+by+up-regulating+pERK+and+GSK-3beta+%28S9P%29. assertion.
- assertion asSentence CRP2+acted+as+a+potent+transcription+coadaptor+that+remodeled+silent+cardiac+myocyte+chromatin+and+directed+serum+response+factor-dependent+smooth+muscle+gene+activity. assertion.
- assertion asSentence The+embryo%27s+cystatin+C+and+F+expression+functions+as+a+protective+mechanism+against+the+maternal+proteinase+cathepsin+S. assertion.
- assertion asSentence CtBp+proteins+repress+transcription+in+a+histone+deacetylase+dependent+or+independent+manner. assertion.
- assertion asSentence The+leukemia-associated+transcription+repressor+AML1%2FMDS1%2FEVI1+requires+CtBP+to+induce+abnormal+growth+and+differentiation+of+murine+hematopoietic+cells. assertion.
- assertion asSentence CtBP1+expressed+in+human+CD4%28%2B%29+T+cells+crucially+contribute+to+Th1%2FTh2+differentiation+via+selective+down-regulation+of+IL-4+synthesis. assertion.
- assertion asSentence CTCF+plays+global+and+essential+role+in+mouse+oocytes+and+preimplantation+embryos. assertion.
- assertion asSentence CTCF+is+required+in+a+dose-dependent+manner+and+is+involved+in+cell+cycle+progression+of+alphabeta+T+cells+in+the+thymus. assertion.