Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence AdipoR2+mRNA+levels+are+decreased+in+diet+induced+diabetic+mice. assertion.
- assertion asSentence Adipoq+signaling+has+a+role+in+preimplantation+embryo+development+and+uterine+receptivity. assertion.
- assertion asSentence SIRPalpha+and+PZR+serve+as+scaffolds+that+facilitate+plasma+membrane+recruitment+and+signaling+of+NS-associated+SHP-2+mutants. assertion.
- assertion asSentence Spontaneous+development+of+cryptogenic+organizing+%28intra-alveolar+fibrosis%29+pneumonia+in+Tomm5-%2F-+mice. assertion.
- assertion asSentence MG23+is+an+essential+component+of+ER-generated+lethal+signals+provoked+upon+DNA+damage%2C+specifying+cell+fate+under+pathophysiological+conditions. assertion.
- assertion asSentence The+Nogo-66%2FNgR+system+is+involved+in+regneeration+of+entorhinal%2Fhippocamal+axonal+lesions+in+in+vitro. assertion.
- assertion asSentence Nogo-B+regulates+liver+fibrosis%2C+at+least+in+part%2C+by+facilitating+the+TGFbeta%2FSmad2+signaling+pathway+in+myofibroblasts. assertion.
- assertion asSentence The+expression+of+SCGB3A1+and+SCGB3A2+are+bidirectionally+regulated+by+oncostatin+M+%28OSM%29+when+examined+in+a+mouse+transformed+Clara+cell+line. assertion.
- assertion asSentence TRPM4+is+critically+involved+in+migration+of+bone+marrow-derived+mast+cells+by+regulation+of+Ca%282%2B%29-dependent+actin+cytoskeleton+rearrangements. assertion.
- assertion asSentence Dock5+is+dispensable+for+normal+mouse+embryogenesis+and+contribution+of+Dock5+toward+myofiber+development. assertion.
- assertion asSentence Zfp467+play+an+important+role+in+adipose+derived+stem+cells+differentiation+to+adipocyte+and+osteoblast. assertion.
- assertion asSentence Insulin-stimulated+dissociation+of+TUG+and+GLUT4+as+an+important+action+by+which+insulin+stimulates+glucose+uptake. assertion.
- assertion asSentence PINK1+mRNA+abundance+is+rather+uniform+throughout+the+different+brain+regions+with+expression+in+cortex%2C+striatum%2C+thalamus%2C+brainstem+and+cerebellum. assertion.
- assertion asSentence Critical+role+in+dopamine+release+and+striatal+synaptic+plasticity+in+the+nigrostriatal+circuit. assertion.
- assertion asSentence Temporal+silencing+of+PINK1+expression+in+adult+mice+increased+striatal+dopamine. assertion.
- assertion asSentence The+mouse+FucU+assembles+into+four+different+oligomeric+forms%2C+among+which+the+smallest+homodimeric+form+is+most+abundant+and+would+be+the+predominant+species+under+physiological+conditions. assertion.
- assertion asSentence Recognizes+pathogens+and+contributes+to+innate+immunity. assertion.
- assertion asSentence Elevated+Pdi+expression+is+cis+regulated+and+is+not+linked+to+diabetes+susceptibility. assertion.
- assertion asSentence Overexpression+of+DDAH-1+increases+basal+levels+of+vascular+NO+and+protects+against+ADMA-induced+endothelial+dysfunction+in+the+cerebral+circulation. assertion.
- assertion asSentence DDAH1+exerts+a+unique+role+in+activating+Akt+that+affects+endothelial+function+independently+of+degrading+endogenous+nitirc+oxide+synthase+inhibitors. assertion.
- assertion asSentence HSP27+induction+is+critical+for+TGF-beta-induced+VEGF+release+in+osteoblasts. assertion.
- assertion asSentence A1+is+a+growth-permissive+antiapoptotic+factor+mediating+postactivation+survival+in+T+cells. assertion.
- assertion asSentence Constructed+cDNA+libraries+from+the+mouse+cerebral+cortex+without+using+pcr. assertion.
- assertion asSentence DDAVP+stimulates+transcription+of+VIT32+via+a+CRE+within+the+proximal+promoter+region+of+the+VIT32+gene. assertion.
- assertion asSentence APRIL+inhibits+allergic+lung+inflammation+by+suppressing+c-maf+expression+and+directly+reducing+IL-13+production+in+CD4%2B+T+cells. assertion.
- assertion asSentence Disruption+of+heparan+sulfate+proteoglycan+conformation+perturbs+B-cell+maturation+and+APRIL-mediated+plasma+cell+survival. assertion.
- assertion asSentence Exclusive+expression+in+the+muscle+cell+lineage. assertion.
- assertion asSentence AIP1+prevents+graft+arteriosclerosis+by+inhibiting+interferon-gamma-dependent+smooth+muscle+cell+proliferation+and+intimal+expansion. assertion.
- assertion asSentence Galpha%2812%2F13%29+proteins+exert+essential+functions+linking+extracellular+signals+to+microtubule+dynamics+and+cell+polarity+via+RhoGEF+and+formin+activity. assertion.
- assertion asSentence A+critical+role+of+IL-36R+ligands+in+the+interface+between+innate+and+adaptive+immunity%2C+leading+to+the+stimulation+of+T+helper+responses. assertion.
- assertion asSentence SMYD3+encodes+a+histone+methyltransferase+involved+in+the+proliferation+of+cancer+cells. assertion.
- assertion asSentence Loss+of+TRIM32+function+induces+a+LGMD2H-like+phenotype+and+strongly+affects+muscle+regeneration+in+vivo. assertion.
- assertion asSentence Activation+of+the+renal+Na%2B%3ACl-+cotransporter+by+angiotensin+II+is+a+WNK4-dependent+process. assertion.
- assertion asSentence Core2+O-glycan+structure+is+essential+for+expression+of+SI+and+DDP-IV+during+intestinal+cell+differentiation. assertion.
- assertion asSentence In+the+renal+cortex+from+diabetic+mice%2C+ACE2+expression+is+increased+at+the+posttranscriptional+level. assertion.
- assertion asSentence ACE-2+protects+against+lung+fibrogenesis+by+limiting+the+local+accumulation+of+the+profibrotic+peptide+ANG+II. assertion.
- assertion asSentence ACE2+regulates+renal+ANP+via+the+generation+of+Ang-%281-7%29. assertion.
- assertion asSentence KAT+I+inhibited+by+equimolar+tryptophan+and+half-life+is+69.7+minutes+at+65+degree+C. assertion.
- assertion asSentence Bcl-2-associated+athanogene+5+%28BAG5%29+is+a+negative+regulator+of+both+Hsp70+and+parkin+function+that+sensitizes+dopaminergic+neurons+to+injury-induced+death. assertion.
- assertion asSentence Overexpression+of+mSpindly+failed+to+enhance+inactivation+of+SAC+and+acceleration+of+the+meiotic+process. assertion.
- assertion asSentence KRAP+is+involved+in+the+proper+regulation+of+IP3R-mediated+Ca2%2B+release. assertion.
- assertion asSentence Mutyh+plays+a+major+role+in+maintaining+intestinal+integrity+by+affecting+the+inflammatory+response. assertion.
- assertion asSentence Overexpression+of+sPRDM16+induces+abnormal+growth+of+stem+cells+and+progenitors+and+cooperates+with+disruption+of+the+p53+pathway+in+the+induction+of+myeloid+leukemia. assertion.
- assertion asSentence The+regulated+docking+of+the+CtBP+proteins+on+PRDM16+controls+the+brown+and+white+fat-selective+gene+programs. assertion.
- assertion asSentence PRDM16+controls+a+bidirectional+cell+fate+switch+between+skeletal+myoblasts+and+brown+adipocytes. assertion.
- assertion asSentence JIP-1+targets+MKP-7+to+dephosphorylate+JNK. assertion.
- assertion asSentence DUSP16+is+an+important+regulator+of+JNK+activity+and+effector+functions+of+CD4+and+CD8+T+cells. assertion.
- assertion asSentence Ablation+of+the+scaffold+protein+JLP+causes+reduced+fertility+in+male+mice. assertion.
- assertion asSentence P2Y2+and+P2Y12+receptor+agonists+are+not+chemoattractants+and+macrophage+chemotaxis+to+complement+C5a+is+phosphatidylinositol+3-kinase+%28PI3K%29-+and+p38+mitogen-activated+protein+kinase+%28MAPK%29-independent. assertion.
- assertion asSentence Plasma+membrane+protein+SCARA5+can+contribute+to+human+hepatocellular+carcinoma+%28HCC%29+tumorigenesis+and+metastasis+via+activation+of+the+FAK+signaling+pathway. assertion.
- assertion asSentence TLT-1s%2C+alternative+transcripts+of+triggering+receptor+expressed+on+myeloid+cell-like+transcript-1+%28TLT-1%29%2C+Inhibits+the+triggering+receptor+expressed+on+myeloid+cell-2+%28TREM-2%29-mediated+signaling+pathway+during+osteoclastogenesis. assertion.
- assertion asSentence ODAM+and+AMTN+are+bona+fide+components+of+the+basal+lamina+associated+with+maturation+stage+ameloblasts+and+they+organize+into+different+subdomains+during+the+early+maturation+stage. assertion.
- assertion asSentence Bcor+plays+a+role+in+differentiation+of+multiple+tissue+lineages+during+early+embryonic+development. assertion.
- assertion asSentence The+tyrosine+kinase+receptor%2C+PTK7%2C+is+implicated+in+beta-catenin-dependent+developmental+processes. assertion.
- assertion asSentence ICK+and+FBX9+are+divergently+transcribed+from+a+bidirectional+promoter+that+is+GC-rich+and+contains+a+CpG+island. assertion.
- assertion asSentence Two+RNA-sensing+proteins%2C+RIG-I+and+MDA5%2C+participate+in+the+IFN+response+to+Legionella+pneumophila. assertion.
- assertion asSentence MDA5+and+TLR3+initiate+pro-inflammatory+signaling+pathways+leading+to+rhinovirus-induced+airways+inflammation+and+hyperresponsiveness. assertion.
- assertion asSentence Myo1e+plays+an+important+role+in+podocyte+function+and+normal+glomerular+filtration. assertion.
- assertion asSentence Tradd+activates+distinct+mechanisms+of+apoptosis+from+the+nucleus+and+the+cytoplasm. assertion.
- assertion asSentence TRADD+is+a+multifunctional+protein+crucial+both+for+TNFR1+signaling+and+other+signaling+pathways+relevant+to+immune+responses. assertion.
- assertion asSentence Rarres2+is+highly+expressed+in+adipose+tissue+and+during+adipocyte+differentiation. assertion.
- assertion asSentence RGS12+is+essential+for+the+terminal+differentiation+of+osteoclasts+induced+by+RANKL. assertion.
- assertion asSentence Loss+of+TMPRSS6+is+associated+with+iron-deficiency+anemia+and+involves+up-regulation+of+Bmp%2FSmad+signaling. assertion.
- assertion asSentence PTB-mediated+splicing+repression+involves+recruitment+of+raver1+as+a+potent+splicing+co-repressor. assertion.
- assertion asSentence Protein+phosphatase+PPM1A+regulates+the+nuclear+export+of+Smad2%2F3+through+targeting+nuclear+exporter+RanBP3. assertion.
- assertion asSentence One+of+the+molecules+involved+in+the+development+or+maintenance+of+skeletal+muscle+strength. assertion.
- assertion asSentence Nanog+expression+is+differentially+regulated+by+the+PI3K%2FAkt+pathway+during+retinoic+acid-induced+cell+differentiation. assertion.
- assertion asSentence Id1+regulates+self-renewal+of+embryonic+stem+cells+by+regulating+levels+of+Nanog+and+Brachyury. assertion.
- assertion asSentence KappaB-Ras2+is+a+nuclear-cytoplasmic+small+GTPase+that+inhibits+NF-kappaB+activation+through+the+suppression+of+transcriptional+activation+of+p65%2FRelA. assertion.
- assertion asSentence The+zinc-finger+domain+of+mouse+PRMT3+is+necessary+%26+sufficient+for+binding+to+human+rpS2.+rpS2+is+methylated+by+PRMT3%2C+implicating+PRMT3+in+ribosomal+function+%26+in+the+regulation+of+protein+synthesis. assertion.
- assertion asSentence h3%2Facidic+calponin+controls+fibroblast+migration+by+regulation+of+ERK1%2F2-mediated+l-caldesmon+phosphorylation. assertion.
- assertion asSentence Fad104+is+essential+for+the+survival+of+newborns+just+after+birth+and+important+for+cell+proliferation%2C+adhesion%2C+spreading+and+migration. assertion.
- assertion asSentence Redundant+function+of+the+heparan+sulfate+6-O-endosulfatases+Sulf1+and+Sulf2+in+fine-tuning+rather+than+regulating+the+development+of+skeletal+structures. assertion.
- assertion asSentence Sulf1+and+Sulf2+differentially+contribute+to+the+generation+of+organ-specific+sulfation+patterns+of+heparan+sulfate. assertion.
- assertion asSentence BAFF-R+deficiency+in+mice+selectively+alters+mature+B2+cell-dependent+cellular+and+humoral+immune+responses+and+limits+the+development+of+atherosclerosis. assertion.
- assertion asSentence Harp+%2B+harmonin+constitute+a+scaffolding+complex+to+facilitate+signal+transduction+in+epithelia. assertion.
- assertion asSentence Mouse+naked+cuticle+2+%28mNkd2%29+is+a+direct+transcriptional+target+of+Hoxc8+in+vivo. assertion.
- assertion asSentence Alcohol+induces+RNA+polymerase+III-dependent+transcription+through+c-Jun+by+co-regulating+TATA-binding+protein+%28TBP%29+and+Brf1+expression. assertion.
- assertion asSentence KBP+expression+is+up-regulated+during+neuronal+development+in+mouse+cortical+neurons. assertion.
- assertion asSentence CA150+FF+domains+recognize+multiple+sites+within+the+Tat-SF1+protein+conforming+to+the+consensus+motif+%28D%2FE%29%282%2F5%29-F%2FW%2FY-%28D%2FE%29%282%2F5%29. assertion.
- assertion asSentence PRCP+is+an+important+component+of+melanocortin+signaling+and+weight+maintenance+via+control+of+active+alpha-MSH1-13+levels. assertion.
- assertion asSentence Murine+prolylcarboxypeptidase+depletion+induces+vascular+dysfunction+with+hypertension+and+faster+arterial+thrombosis. assertion.
- assertion asSentence PLCdelta1+and+PLCdelta3+are+essential+in+trophoblasts+for+placental+development. assertion.
- assertion asSentence Hsdl2+is+widely+expressed+in+normal+mouse+tissues+and+its+expression+level+in+liver+increases+after+inducement+with+cholesterol+food. assertion.
- assertion asSentence APJ+and+apelin+act+downstream+of+Cripto+to+specify+embryonic+stem+cells+toward+the+cardiac+lineage+through+extracellular+signal-regulated+kinase%2Fp70S6+kinase+signaling+pathway. assertion.
- assertion asSentence Rictor-T1135+phosphorylation+acts+in+parallel+with+other+mTORC1-dependent+feedback+mechanisms%2C+such+as+those+affecting+IRS-1+signaling+to+PI3K%2C+to+regulate+the+response+of+Akt+to+insulin. assertion.
- assertion asSentence S6K1+acts+on+fatty+synthesis+by+regulating+mSREBP1c+expression. assertion.
- assertion asSentence Lack+of+S6K1+impairs+the+generation+of+de+novo+adipocytes+when+mice+are+challenged+with+a+high+fat+diet%2C+consistent+with+a+reduction+in+early+adipocyte+progenitors. assertion.
- assertion asSentence Cox7a2+decreased+P70S6K+phosphorylation%2C+reduced+StAR+expression+and+consequently+inhibited+LH-induced+testosterone+biosynthesis+in+the+TM3+Leydig+cells. assertion.
- assertion asSentence Metabolic+functions+of+S6K+in+vivo+play+a+key+role+as+a+molecular+interface+connecting+dietary+lipids+to+the+endogenous+control+of+energy+metabolism. assertion.
- assertion asSentence DDX41+is+an+additional+DNA+sensor+that+depends+on+STING+to+sense+pathogenic+DNA. assertion.
- assertion asSentence Adipo1+and+2+serve+as+the+predominant+receptors+for+adiponectin+in+vivo+and+play+important+roles+in+the+regulation+of+glucose+and+lipid+metabolism%2C+inflammation+and+oxidative+stress+in+vivo. assertion.
- assertion asSentence Adipoq+signaling+has+a+role+in+preimplantation+embryo+development+and+uterine+receptivity. assertion.
- assertion asSentence A+single+substitution+in+a+memory-induced+RNA-binding+protein%2C+hnRNPLL%2C+destabilized+an+RNA-recognition+domain+that+bound+with+micromolar+affinity+to+RNA+containing+the+Ptprc+exon-silencing+sequence. assertion.
- assertion asSentence In+T+cells+with+no+CD45+protein%2C+hnRNPLL+mutation+diminishes+peripheral+T+cell+accumulation+and+demonstrates+that+hnRNPLL+regulates+T+cell+longevity+independently+from+its+effects+on+CD45+splicing. assertion.
- assertion asSentence Tripeptidyl+peptidase+I+%28Tpp1%29+confers+telomere+end+protection+by+recruiting+Pot1a+and+Pot1b+to+telomeres. assertion.
- assertion asSentence Pot1b+plays+an+essential+role+in+hematopoietic+stem+cell+survival. assertion.
- assertion asSentence The+mitochondrial+gene+for+NADH+dehydrogenase+2+is+able+to+modulate+susceptibility+to+type+1+diabetes+in+NOD+mice. assertion.
- assertion asSentence GlialCAM%2C+an+immunoglobulin-like+cell+adhesion+molecule+is+expressed+in+glial+cells+of+the+central+nervous+system. assertion.
- assertion asSentence DDX41+is+an+additional+DNA+sensor+that+depends+on+STING+to+sense+pathogenic+DNA. assertion.