Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Nos-3+loss+of+function+mutant+suppresses+the+lethality+of+par-2+mutants+by+regulating+PAR-6+protein+levels. assertion.
- assertion asSentence Polarity+in+the+C.+elegans+zygote+is+initiated+by+redundant+ECT-2-+and+PAR-2-dependent+mechanisms+that+lower+PAR-3+levels+locally%2C+triggering+a+positive-feedback+loop+that+polarizes+the+entire+cortex. assertion.
- assertion asSentence MAB-10%2FNAB+acts+with+LIN-29%2FEGR+to+regulate+terminal+differentiation+and+the+transition+from+larva+to+adult+in+C.+elegans. assertion.
- assertion asSentence DYC-1+interacts+with+ZYX-1%2C+the+homologue+of+the+vertebrate+focal+adhesion+LIM+domain+protein+zyxin. assertion.
- assertion asSentence Galectins+LEC-6+and+LEC-1+recognize+a+chemically+synthesized+Galbeta1-4Fuc+disaccharide+unit. assertion.
- assertion asSentence Mes-2+mutants+suppress+mab-3. assertion.
- assertion asSentence Mes-2+orchestrates+large-scale+changes+in+chromatin+organization+and+gene+expression+to+promote+the+timely+loss+of+developmental+plasticity. assertion.
- assertion asSentence TAC-1+is+a+major+regulator+of+microtubule+length+in+the+C.+elegans+embryo. assertion.
- assertion asSentence The+carbohydrate+specificity+of+the+16kDa+%22proto%22+galectin+mediates+binding+to+blood+group+precursor+oligosaccharides+and+gangliosides. assertion.
- assertion asSentence Pseudomonas+aeruginosa+suppresses+host+immunity+by+activating+the+DAF-2+insulin-like+signaling+pathway+in+Caenorhabditis+elegans. assertion.
- assertion asSentence Syntaxin+is+one+of+three+essential+presynaptic+SNARE+proteins+that+acts+in+concert+with+other+proteins+to+mediate+fusion+of+synaptic+vesicles+with+the+presynaptic+membrane. assertion.
- assertion asSentence Wip1+phosphatase+promotes+apoptosis+in+p53-negative+tumors+and+protects+normal+tissues+during+treatment+with+anticancer+agents. assertion.
- assertion asSentence KLP-6+kinesin+is+required+for+male+mating+behaviors+and+polycystin+localization+in+sensory+neuron+cilia. assertion.
- assertion asSentence UNC-53%2FNAV2%2C+through+its+calponin+homology+domain%2C+acts+as+a+scaffold+that+links+ABI-1+to+the+ARP2%2F3+complex+to+regulate+actin+cytoskeleton+remodeling. assertion.
- assertion asSentence LET-756+exerts+its+functions+through+a+balance+between+a+synergy+of+several+nuclear+localization+signals+and+attenuated+secretion+signal. assertion.
- assertion asSentence Regulation+of+physiological+germ+cell+apoptosis+is+specifically+influenced+by+certain+functions+of+the+CGH-1%2FCAR-1+RNA-proteinP+complex. assertion.
- assertion asSentence Prolonged+life+span+of+Clk+mutants+cannot+be+attributed+to+reduced+metabolic+rate+or+an+increased+activity+of+the+major+antioxidant+enzymes+catalase+and+SOD. assertion.
- assertion asSentence DNA+damage+checkpoint+protein+clk-2+suppresses+the+frequency+of+mutation+by+ensuring+that+spontaneous+DNA+damage+is+accurately+repaired+in+C.+elegans+germ+cells. assertion.
- assertion asSentence MRP-4+localizes+to+endocytic+compartments+and+its+levels+are+elevated+in+the+absence+of+CUP-5. assertion.
- assertion asSentence In+the+P11+lineage%2C+a+complex+between+MAB-5+and+the+Pbx+homolog+CEH-20+directly+regulates+transcription+of+the+BH3+domain+gene+egl-1+to+initiate+programmed+cell+death. assertion.
- assertion asSentence The+C.+elegans+Hox+gene+egl-5+is+frequired+for+correct+development+of+the+hermaphrodite+hindgut+and+for+the+response+to+rectal+infection+by+Microbacterium+nematophilum. assertion.
- assertion asSentence Loss+of+BATH-42+function+leads+to+increased+RIC-3+expression+and+decreased+activity+of+nicotinic+acetylcholine+receptors+in+Caenorhabditis+elegans+vulva+muscles. assertion.
- assertion asSentence Mutations+in+NPC1+in+two+Brazilian+patients+with+Niemann-Pick+disease+type+C+and+progressive+supranuclear+palsy-like+presentation. assertion.
- assertion asSentence Dynamic+localization+of+gpr-1+to+cell+cortex+forces+generation+of+domains+during+spindle+positioning. assertion.
- assertion asSentence Fli-1+plays+an+important+role+in+regulating+the+actin-dependent+events+during+C.+elegans+development. assertion.
- assertion asSentence Interaction+between+RDE-2+and+MUT-7+is+required+for+efficient+RNA+interference. assertion.
- assertion asSentence CDK-1+blocks+rotation+by+inhibiting+dynein+association+with+microtubules. assertion.
- assertion asSentence The+deubiquitinating+enzyme+ubiquitin-specific+protease-46+%28USP-46%29+regulates+the+abundance+of+the+glutamate+receptor+GLR-1+in+the+ventral+nerve+cord+of+Caenorhabditis+elegans. assertion.
- assertion asSentence Xol-1+is+a+transcriptional+target+of+the+terminal+sex-determining+factor+tra-1. assertion.
- assertion asSentence Essential+role+of+sbp-1+activation+in+oxygen+deprivation+induced+lipid+accumulation+and+increase+in+body+width%2Flength+ratio+in+Caenorhabditis+elegans. assertion.
- assertion asSentence The+UNG-1+enzyme+is+an+active+uracil-DNA+glycosylase+involved+in+repair+of+DNA+damage+induced+by+ionizing+radiation. assertion.
- assertion asSentence Tim-1+has+a+role+in+sister+chromatid+cohesion. assertion.
- assertion asSentence NUD-1+possesses+ATP-independent+chaperone+activity+comparable+to+that+of+small+heat+shock+proteins+and+cochaperones+and+changes+in+phosphorylation+state+functionally+alter+chaperone+activity+in+a+phosphomimetic+NUD-1+mutant. assertion.
- assertion asSentence Dynein+and+Lis1%2C+albeit+functioning+in+identical+processes%2C+are+targeted+partially+independently+of+one+another. assertion.
- assertion asSentence CDK-5+regulates+DCV+polarity+by+both+promoting+DCV+trafficking+in+axons+and+preventing+dynein-dependent+DCV+trafficking+into+dendrites. assertion.
- assertion asSentence Fem-1+protein+is+a+substrate-specific+adaptor+for+a+CUL-2-based+ubiquitin+ligase. assertion.
- assertion asSentence DAF-18+modulates+the+PI3K+signaling+pathway+to+activate+DAF-16%2FFOXO+and+promote+developmental+neurite+outgrowth. assertion.
- assertion asSentence LAD-2%2C+a+Caenorhabditis+elegans+L1CAM%2C+functions+in+axon+pathfinding. assertion.
- assertion asSentence EEL-1+fine-tunes+DNA+damageinduced+apoptosis+signalling+in+the+C.+elegans+germline. assertion.
- assertion asSentence ROS+generation+by+Ce-Duox1%2FBLI-3+activates+a+protective+SKN-1+response+via+p38+MAPK+signaling. assertion.
- assertion asSentence ZEN-4%2FMKLP1+and+CYK-4%2FRhoGAP+regulate+an+early+step+in+epithelial+polarization+that+is+required+to+establish+the+apical+domain+and+apical+junctions+. assertion.
- assertion asSentence The+structural+features+of+the+interactions+between+monomeric+and+dimeric+motor+domain+constructs+of+ZEN-4+and+microtubules. assertion.
- assertion asSentence Selenoprotein+TRXR-1+and+GSR-1+are+essential+for+removal+of+old+cuticle+during+molting+in+Caenorhabditis+elegans. assertion.
- assertion asSentence Flp-10+is+required+for+the+sensory+transduction+involved+in+male+turning+behavior. assertion.
- assertion asSentence The+6+Ig%2F5+FnIII+domain+protein+SAX-7+acts+autonomously+in+the+nervous+system+to+maintain+axon+position+in+the+ventral+nerve+cord+of+the+nematode. assertion.
- assertion asSentence Cloning+of+poly%28ADP-ribose%29+glycohydrolases+%28pme-3%29. assertion.
- assertion asSentence Provide+several+interdependent+reasons+for+the+heterodimerization+of+the+kinesin-2+motor+KLP11%2FKLP20+of+Caenorhabditis+elegans+cilia. assertion.
- assertion asSentence Pumilio-fem-3+mRNA+binding+factor+%28PUF%29+RNA-binding+proteins+achieve+that+specificity+through+variations+on+a+conserved+scaffold. assertion.
- assertion asSentence Elt-1+is+a+key+regulator+of+neuronal+function+in+larvae+and+adult+worms. assertion.
- assertion asSentence Uba-1+plays+multiple+roles+throughout+C.+elegans+development. assertion.
- assertion asSentence Completely+suppresses+massive+increase+in+the+level+of+double-strand+breaks+caused+by+depletion+of+him-6+and+top-3. assertion.
- assertion asSentence The+GTL-1+mainly+contributes+to+appropriate+Mg%282%2B%29+responsiveness+of+the+outwardly+rectifying+current. assertion.
- assertion asSentence Goa-1+Goalpha+and+let-60+Ras+act+in+parallel+to+gpc-1+in+olfactory+pathway. assertion.
- assertion asSentence MAGI-1+functions+as+an+%22organizer%22+that+ensures+the+correct+segregation+of+different+cell+adhesion+complexes+into+distinct+domains+along+the+lateral+plasma+membrane. assertion.
- assertion asSentence WRM-1+downregulates+POP-1+by+promoting+its+phosphorylation+by+the+MAP+kinase+LIT-1+and+subsequent+nuclear+export+via+a+14-3-3+protein%2C+PAR-5. assertion.
- assertion asSentence Ced-3+causes+cell+death+in+this+nematode. assertion.
- assertion asSentence Eg5+is+a+rate-limiting+component+of+the+cellular+machinery+that+drives+spindle+assembly+in+vertebrates. assertion.
- assertion asSentence Xphb1+represses+E2F1+activity. assertion.
- assertion asSentence Laminin+receptor+precursor+cleavage+by+ST3+plays+a+role+in+both+physiological+and+pathological+processes. assertion.
- assertion asSentence The+structural+function+of+VegT+mRNA+in+Xenopus+oocyte+depends+on+its+combinatory+signals+for+the+induction+or+facilitation+and+for+the+maintenance+of+the+depolymerization+vs.+polymerization+status+of+cytokeratin+filaments. assertion.
- assertion asSentence cetn2+localizes+to+the+Xenopus+nuclear+pore+and+plays+a+role+in+mRNA+and+protein+export. assertion.
- assertion asSentence Cyclin+B1+displays+cytoskeleton-dependent+localization+in+blastomere+cortex+during+Xenopus+embryonic+cell+cycle. assertion.
- assertion asSentence DYRK1A+is+required+for+oocyte+maturation+induced+by+wild-type+p21. assertion.
- assertion asSentence KLF2+and+ERG+associate+in+a+physical+complex+and+the+two+proteins+synergistically+activate+transcription+of+Flk1. assertion.
- assertion asSentence A+consensus+Oct1+binding+site+is+required+for+the+activity+of+the+Xenopus+Cdx4+promoter. assertion.
- assertion asSentence Mcm2-7+associate+with+Cdc45+and+GINS+to+form+a+relatively+stable+CMG+%28Cdc45-MCM-GINS%29+complex. assertion.
- assertion asSentence Cdk1+phosphorylation+of+BubR1+controls+spindle+checkpoint+arrest+and+plk-mediated+formation+of+the+3F3%2F2+epitope. assertion.
- assertion asSentence In+the+melanotrope%2C+biosynthesis+and+processing+occur+along+a+secretory+granule+maturation+axis+and+light+controls+the+biosynthesis+and+secretion+of+POMC+end-products. assertion.
- assertion asSentence The+p24+proteins+fulfil+their+role+in+secretory+protein+biosynthesis+via+COPI-+or+COPII-coated+transport+vesicles. assertion.
- assertion asSentence Lox-related+enzymes+are+required+for+the+proper+formation+of+the+ECM+during+X.+laevis+development. assertion.
- assertion asSentence The+alpha-neurexins+are+differentially+regulated+during+development+with+respect+to+gene+temporal+and+spatial+expression+and+alternative+splicing. assertion.
- assertion asSentence Ceramide+mediates+TNF-alpha+inhibition+of+the+renal+epithelial+sodium+channel+%28ENaC%29+via+a+pathway+associated+with+PKC-dependent+externalization+of+phosphatidylserine+%5BENaCand+protein+kinase+C%5D. assertion.
- assertion asSentence Xhes6+is+essential+for+XmyoD+induction+and+acts+by+relieving+Groucho-mediated+repression+of+gene+expression. assertion.
- assertion asSentence Intracellular+Ca%282%2B%29+plays+a+role+as+the+second+messenger+in+hypotonic+stress-induced+Na%28%2B%29+transport+by+stimulating+transcription+of+SGK1+and+ENaC+subunits+%5BSGK1+and+ENaC%5D. assertion.
- assertion asSentence The+V-ATPase+accessory+subunit+Ac45+represents+the+first+regulator+of+the+proton+pump+and+controls+V-ATPase-mediated+granular+acidification+that+is+necessary+for+efficient+prohormone+processing. assertion.
- assertion asSentence BCL6+inhibits+transcription+by+competing+for+the+Notch1+intracellular+domain%2C+preventing+the+coactivator+Mastermind-like1+%28MAM1%29+from+binding. assertion.
- assertion asSentence XTcf-3+regulates+XCIRP+during+anterior+neural+development+in+Xenopus. assertion.
- assertion asSentence Ashwin+regulates+cell+survival+and+anteroposterior+patterning. assertion.
- assertion asSentence Xklp1+affects+microtubule+polymerization+during+M-phase. assertion.
- assertion asSentence In+the+developing+diencephalon%2C+Caspase3+acts+downstream+of+Barhl2+in+limiting+neuroepithelial+cell+proliferation+by+inhibiting+beta-catenin+activation. assertion.
- assertion asSentence Rad51+has+a+role+at+the+replication+fork+protecting+DNA+from+Mre11-dependent+degradation. assertion.
- assertion asSentence Interaction+of+NF7+with+active+transcriptional+units+of+RNA+polymerase+II+is+mediated+by+a+trimeric+B+box. assertion.
- assertion asSentence Overexpression+of+xMELK+leads+to+failure+of+cytokinesis+and+impairs+accumulation+RhoA-+a+pivotal+regulator+of+cytokinesis. assertion.
- assertion asSentence During+early+Xenopus+development+Myf5+protein+regulates+a+distinct+myogenic+program. assertion.
- assertion asSentence Op18+reveals+the+contribution+of+nonkinetochore+microtubules+to+the+dynamic+organization+of+the+vertebrate+meiotic+spindle. assertion.
- assertion asSentence Direct+interaction+and+interdependence+between+the+Otx2+and+Sox2+proteins+coordinate+Rax+expression+in+eye+development%2C+providing+molecular+linkages+among+the+genes+responsible+for+ocular+malformation. assertion.
- assertion asSentence Cardiogenesis+in+mesoderm+depends+on+Nodal-mediated+induction+of+Cerberus+in+underlying+endoderm. assertion.
- assertion asSentence SLBP+stimulates+histone+translation+at+an+early+step+in+the+intiaition+pathway. assertion.
- assertion asSentence PACAP+stimulates+the+expression+of+BDNF+transcript+IV. assertion.
- assertion asSentence ATM+and+ATR+prevent+accumulation+of+chromosomal+abnormalities+by+promoting+Mre11%2FRad50%2FNbs1+dependent+recovery+of+collapsed+replication+forks. assertion.
- assertion asSentence ephrinB1+associates+with+the+Par+polarity+complex+protein+Par-6+and+can+compete+with+the+small+GTPase+Cdc42+for+association+with+Par-6. assertion.
- assertion asSentence Chk2%2FCds+kinase+operates+at+a+switch+between+cell+cycle+arrest+or+apoptosis+in+response+to+genomic+assaults. assertion.
- assertion asSentence ATM+and+ATR+prevent+accumulation+of+chromosomal+abnormalities+by+promoting+Mre11%2FRad50%2FNbs1+dependent+recovery+of+collapsed+replication+forks. assertion.
- assertion asSentence TopBP1+and+DNA+polymerase-alpha+directly+recruit+the+9-1-1+complex+to+stalled+DNA+replication+forks. assertion.
- assertion asSentence Kaiso+is+a+bimodal+modulator+for+Wnt%2Fbeta-catenin+signaling. assertion.
- assertion asSentence The+degradation+machinery+of+the+canonical+Wnt+pathway+modulates+p120-catenin+protein+stability+through+mechanisms+shared+with+those+regulating+beta-catenin. assertion.
- assertion asSentence Ni2%2B+prevents+ENaC+to+be+downregulated+by+self-inhibition. assertion.
- assertion asSentence ICIS+and+Aurora+B+coregulate+the+microtubule+depolymerase+Kif2a. assertion.
- assertion asSentence The+cloning+of+the+gene+ID14+expressed+in+tadpoles+and+adults+of+Xenopus+laevis. assertion.
- assertion asSentence The+RGS2+proteins+recognize+GPCRs+to+confer+signalling+specificity. assertion.