Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Role+of+the+cellular+localization+of+HDAC4+in+the+events+leading+to+ataxia+telangiectasia+neurodegeneration. assertion.
- assertion asSentence CPEB3+is+a+sequence-specific+translational+regulatory+protein. assertion.
- assertion asSentence Adamts18+is+expressed+in+the+lens+and+retina+in+the+developing+murine+eye. assertion.
- assertion asSentence Mouse+Samd9L+revealed+near-ubiquitous+expression%2C+with+the+highest+level+in+the+kidney%2C+a+major+organ+regulating+calcium-phosphate+homeostasis+and+the+site+of+calcitonin+hormonal+action. assertion.
- assertion asSentence Mtrr+deficiency+adversely+impacts+reproductive+outcomes+and+cardiac+development+in+mice. assertion.
- assertion asSentence GPRC6A+is+a+promiscuous+L-alpha-amino+acid+receptor+most+potently+activated+by+basic+amino+acids. assertion.
- assertion asSentence Mohawk+is+an+important+regulator+of+vertebrate+development. assertion.
- assertion asSentence AS160provides+a+mechanism+linking+AMP+kinase+signaling+to+glucose+uptake. assertion.
- assertion asSentence C1ql+proteins+are+secreted+signaling+molecules+that+bind+to+BAI3+and+act%2C+at+least+in+part%2C+to+regulate+synapse+formation+and%2For+maintenance. assertion.
- assertion asSentence Alkbh1+performs+important+functions+in+placental+trophoblast+lineage+differentiation+and+participates+in+mechanisms+of+transcriptional+regulation. assertion.
- assertion asSentence Ameliorates+muscular+dystrophy+in+mdx+mice. assertion.
- assertion asSentence Heregulin+ligand+contributes+to+activation+of+ErbB-2%2FErb-3+in+mouse+mammary+tumor+cells+in+an+autocrine+or+paracrine+fashion. assertion.
- assertion asSentence NRG1+is+pro-myelination+in+mouse+Schwann+cells. assertion.
- assertion asSentence NRG1beta+and+NRG3+can+promote+the+proliferation+of+mouse+spermatogonia. assertion.
- assertion asSentence Type+III+Nrg1+back+signaling+enhances+functional+TRPV1+along+sensory+axons+contributing+to+basal+and+inflammatory+thermal+pain+sensation. assertion.
- assertion asSentence Bone+marrow-derived+mesenchymal+stem+cells+up-regulate+skeletal+muscle+acetylcholine+receptor+delta+subunit+through+NRG%2FErbB3-mediated+mitogen-activated+protein+kinase+pathway. assertion.
- assertion asSentence MTSS1+promotes+actin+assembly+at+intercellular+junctions+and+is+required+for+integrity+of+kidney+epithelia. assertion.
- assertion asSentence Tsga10+expression+starts+in+4.5-7.5+dpc+mouse+embryos+and+continues+throughout+embryogenesis. assertion.
- assertion asSentence Cysteamine+%282-aminoethanethiol%29+dioxygenase+%28ADO%29is+encoded+by+the+gene+Gm237+and+belongs+to+the+DUF1637+protein+family. assertion.
- assertion asSentence Trib1+transduced+hematopoietic+stem+cells+developed+acute+myeloid+leukemia. assertion.
- assertion asSentence Cc2d1a+is+required+for+mouse+survival+and+performs+essential+function+in+controlling+functional+maturation+of+synapses. assertion.
- assertion asSentence N%2CN%27-dibenzyl-1%2C4-diaminobutanes%2C+with+only+two+nitrogens%2C+are+also+substrates+of+polyamine+oxidase. assertion.
- assertion asSentence Role+of+bulk+water+in+hydrolysis+of+the+rhodopsin+chromophore. assertion.
- assertion asSentence SATB2+acts+as+a+molecular+node+in+a+transcriptional+network+regulating+skeletal+development+and+osteoblast+differentiation. assertion.
- assertion asSentence Satb2+regulates+callosal+projection+neuron+identity+in+the+developing+cerebral+cortex. assertion.
- assertion asSentence SATB2+acts+as+a+potent+transcription+factor+to+enhance+osteoblastogenesis+and+promote+bone+regeneration. assertion.
- assertion asSentence Osx+is+an+upstream+regulator+of+Satb2+during+bone+formation. assertion.
- assertion asSentence Stat-interacting+LIM+protein+as+the+critical+Stat+ubiquitin+E3+ligase+involved+in+osteopontin+regulation+of+Stat1. assertion.
- assertion asSentence A+weak+allele+of+the+IFT-A+gene%2C+Ift144%2C+caused+subtle+defects+in+cilia+structure+and+ectopic+activation+of+the+Shh+pathway. assertion.
- assertion asSentence Guanylyl+cyclase+C+signaling+plays+a+protective+role+in+the+integrity+of+the+intestinal+mucosal+barrier+by+regulating+myosin+light+chain+kinase+activation+and+tight+junction+disassembly. assertion.
- assertion asSentence Involvement+of+the+TIP39%2FPTH2-R+system+in+the+pathways+involved+in+the+successful+development+of+the+pups. assertion.
- assertion asSentence Xist+is+transcriptionnally+repressed+in+undifferentiated+ES+cells+through+Tsix-independent+mechanisms. assertion.
- assertion asSentence Tsix+silences+Xist+through+modification+of+the+chromatin+structure. assertion.
- assertion asSentence Role+for+mRNA+nuclear+degradation+pathways+in+the+critical+regulation+of+spliced+Xist+mRNA+levels+and+the+onset+of+the+X-inactivation+process. assertion.
- assertion asSentence SATB1+is+a+crucial+silencing+factor+contributing+to+the+initiation+of+X+inactivation. assertion.
- assertion asSentence NTRAP+regulates+retrograde+neurotrophic+signaling+by+controlling+the+formation+of+signaling+endosomes. assertion.
- assertion asSentence Impairment+of+TET2+function+or%2Fand+expression+predisposes+to+the+development+of+hematological+malignancies. assertion.
- assertion asSentence Specific+recruitment+of+MLL1+requires+multiple+interactions+and+is+a+precondition+for+stable+recruitment+of+MLL1+fusion+proteins+to+HoxA9+in+leukemogenesis. assertion.
- assertion asSentence Developmentally+induced+Mll1+loss+reveals+defects+in+postnatal+haematopoiesis. assertion.
- assertion asSentence The+long%2C+noncoding+RNA+%28lncRNA%29+Mistral+%28Mira%29+activates+transcription+of+the+homeotic+genes+Hoxa6+and+Hoxa7+in+mouse+embryonic+stem+cells+%28mESC%29+by+recruiting+MLL1+to+chromatin. assertion.
- assertion asSentence Notch1+intracellular+domain+inhibits+myocardin-dependent+transcription+om+smooth+muscle. assertion.
- assertion asSentence Vascular+smooth+muscle+proteasomal+degradation+of+myocardin+is+required+for+its+transcriptional+activity. assertion.
- assertion asSentence ARTD15+features+an+alpha-helical+domain+that+packs+against+its+transferase+domain+without+making+direct+contact+with+the+NAD%28%2B%29-binding+crevice+or+the+donor+loop. assertion.
- assertion asSentence DUOX2+plays+pivotal+roles+in+TLR5-dependent+inflammatory+response+of+nasal+airway+epithelium. assertion.
- assertion asSentence A+functional+interplay+between+the+PRC2+complex+and+the+H3K4me3+demethylase+Rbp2+%28Jarid1a%29+in+mouse+embryonic+stem+%28ES%29+cells. assertion.
- assertion asSentence SCIRR1+ise+involved+in+the+succeeding+injury+and%2For+repair+processes+of+the+injured+spinal+cord. assertion.
- assertion asSentence Armcx+genes+regulate+mitochondrial+trafficking+in+neurons+and+interact+with+Miro+1%2F2+and+Trak2. assertion.
- assertion asSentence Required+for+morphogenesis+of+the+preimplantation+mouse+embryo. assertion.
- assertion asSentence Vezatin+associates+with+actin+filaments+at+cell-cell+junctions. assertion.
- assertion asSentence Presynaptic+function+is+altered+in+hippocampal+brain+slices+of+HIP1-deficient+mice+demonstrating+delayed+recovery+from+synaptic+depression+and+a+reduction+in+paired-pulse+facilitation. assertion.
- assertion asSentence WIP+participates+in+the+actin+reorganization+that+leads+to+ruffle+formation. assertion.
- assertion asSentence WIP+regulates+FcepsilonRI-mediated+mast+cell+activation+by+regulating+Syk+levels+and+actin+cytoskeleton+rearrangement. assertion.
- assertion asSentence CDX1+and+CDX2+bind+the+promoter+region+of+SLC5A8+and+up-regulate+its+expression+in+cultured+cells+and+in+colonic+epithelium. assertion.
- assertion asSentence Socs2+and+Elf5+are+key+members+of+the+set+of+prolactin-regulated+genes+that+mediate+prolactin-driven+mammary+development. assertion.
- assertion asSentence SOCS2-induced+proteasome-dependent+TRAF6+degradation+is+a+common+anti-inflammatory+pathway+for+control+of+innate+immune+responses. assertion.
- assertion asSentence Tph2+plays+a+critical+role+in+the+maintenance+of+brain+serotonin+homeostasis. assertion.
- assertion asSentence In+mice+tph2+expression+during+pre-+and+postnatal+development+of+brain. assertion.
- assertion asSentence Mechanistically%2C+p120RasGAP+interacted+with+the+cytoplasmic+domain+of+integrin+alpha-subunits+via+its+GAP+domain+and+competed+with+Rab21+for+binding+to+endocytosed+integrins. assertion.
- assertion asSentence Both+fibulin-3+and+-5+are+important+in+maintaining+pelvic+organ+support+in+mice. assertion.
- assertion asSentence The+circadian+rhythm+of+neuromedin+U+expression+in+the+suprachiasmatic+nucleus+does+not+drive+a+circadian+rhythm+of+corticotrophin-releasing+factor+in+the+paraventricular+nucleus. assertion.
- assertion asSentence Required+for+functional+heme+biosynthesis+in+erythroid+cells. assertion.
- assertion asSentence Activation+of+NLRP3-mediated+inflammatory+response+pathways+is+an+important+venue+associated+with+host+response+and+pathogenesis+of+N.+gonorrhoeae. assertion.
- assertion asSentence By+signaling+through+TLR2%2F4%2C+biglycan+stimulates+the+expression+of+NLRP3+and+pro-IL-1beta+mRNA. assertion.
- assertion asSentence Glyburide+inhibits+the+NALP3+inflammasome. assertion.
- assertion asSentence The+inhibition+of+Nlrp3+inflammasome+activity+can+diminish+the+acute+inflammation+and+damage+associated+with+tissue+injury. assertion.
- assertion asSentence Nlrp3+gene+expression+in+hematopoietic+cells%2C+rather+than+intestinal+epithelial+cells+or+stromal+cells%2C+is+responsible+for+protection+against+increased+tumorigenesis. assertion.
- assertion asSentence The+LRR+domain+of+cryopyrin+plays+a+role+in+mediating+MSU+crystal-induced+inflammation. assertion.
- assertion asSentence A+Yersinia+effector+with+enhanced+inhibitory+activity+on+the+NF-kappaB+pathway+activates+the+NLRP3%2FASC%2Fcaspase-1+inflammasome+in+macrophages. assertion.
- assertion asSentence The+NLRP3+inflammasome+is+a+factor+in+the+secretion+of+matured+IL-1+beta+by+neutrophils. assertion.
- assertion asSentence JMJD3+demethylates+di-+and+trimethylated+lysine+27+of+histone+H3+in+vitro+and+in+cells. assertion.
- assertion asSentence JMJD3+induces+p53+stabilization+in+mouse+NSCs+through+ARF-dependent+mechanisms%2C+directly+interacts+with+p53+and%2C+importantly%2C+causes+nuclear+accumulation+of+p53. assertion.
- assertion asSentence ARRB2+acts+to+limit+JNK%2FERK+activation+and+survival+in+macrophages. assertion.
- assertion asSentence Beta-arrestin+2+functions+to+negatively+regulate+the+inflammatory+response+in+polymicrobial+sepsis. assertion.
- assertion asSentence Deficiency+of+beta-arrestin+2+augments+stress-induced+immune+suppression. assertion.
- assertion asSentence The+Hbo1-Brd1+complex+is+the+major+H3K14+HAT+required+for+transcriptional+activation+of+erythroid+developmental+regulator+genes. assertion.
- assertion asSentence An+acute+change+of+Per2+and+Rev-erbalpha+gene+expression+mediated+by+refeeding-induced+insulin+secretion+is+a+critical+step+mediating+the+early+phase+of+feeding-induced+entrainment+of+the+liver+clock. assertion.
- assertion asSentence Activation+of+neurons+in+the+nucleus+of+the+solitary+tract+following+administration+of+T2R+agonists+to+the+GI+tract+involves+CCK%281%29+and+Y%282%29+receptors+located+on+vagal+afferent+terminals+in+the+gut+wall. assertion.
- assertion asSentence Trib2+transduced+hematopoietic+stem+cells+developed+acute+myeloid+leukemia. assertion.
- assertion asSentence THIK-1+and+THIK-2+are+abundantly+expressed+in+the+proximal+and+distal+nephron+of+the+mammalian+kidney. assertion.
- assertion asSentence PIR2%2C+by+being+induced+by+TAp73+and+degrading+DeltaNp73%2C+differentially+regulates+TAp73%2FDeltaNp73+stability. assertion.
- assertion asSentence Cdc14b+is+required+for+efficient+DNA+damage+repair. assertion.
- assertion asSentence RasGap+peptide+fragment+efficiently+increases+the+overall+resistance+of+beta-cells+to+noxious+stimuli+without+interfering+with+the+physiological+functions+of+the+cells. assertion.
- assertion asSentence After+transduction+of+retinoic+acid+receptor+beta2%2C+prolific+neurite+outgrowth+occurs+in+adult+rodent+spinal+cord. assertion.
- assertion asSentence TASK-like+conductances+are+more+prevalent+in+inhibitory+interneurons+than+previously+supposed. assertion.
- assertion asSentence Kcnk9+gene+is+imprinted%2C+with+preferential+expression+from+the+maternal+allele+in+mouse+brain. assertion.
- assertion asSentence MRTF-A+regulates+myofibroblast+activation+and+fibrosis+in+response+to+the+renin-angiotensin+system+and+post-myocardial+infarction+remodeling. assertion.
- assertion asSentence MRTF-A+nuclear+accumulation+following+stimulation+with+serum%2C+actin+drugs+or+acute+mechanical+stress+is+prevented+within+mechanically+loaded%2C+anchored+matrices+at+tensional+homeostasis. assertion.
- assertion asSentence Ceramide+kinase+is+a+key+regulator+of+ceramide+1-phosphate%2C+dihydroceramide+and+ceramide+levels%2C+with+important+implications+for+neutrophil+homeostasis+and+innate+immunity+regulation. assertion.
- assertion asSentence The+Hbo1-Brd1+complex+is+the+major+H3K14+HAT+required+for+transcriptional+activation+of+erythroid+developmental+regulator+genes. assertion.
- assertion asSentence Changes+in+Muc19%2FSmgc+gene+expression+delineate+multiple+stages+of+salivary+mucous+cell+cytodifferentiation+and+subsequent+maturation+during+embryonic+gland+development+through+the+first+4+weeks+of+postnatal+life. assertion.
- assertion asSentence AKAP150+acts+as+a+key+regulator+in+the+two+cAMP+pathways+to+control+PKB%2FAkt+phosphorylation. assertion.
- assertion asSentence Epac1+is+upregulated+during+neointima+formation+and+promotes+vascular+smooth+muscle+cell+migration. assertion.
- assertion asSentence Epac+mediates+PACAP-dependent+long-term+depression+in+the+hippocampus. assertion.
- assertion asSentence SENP1+is+essential+for+cell+survival+during+endoplasmic+reticulum+stress. assertion.
- assertion asSentence Cardiac+AC5+declines+with+development+and+increases+with+pressure-overload+hypertrophy. assertion.
- assertion asSentence Ca%282%2B%29-mediated+inhibition+of+AC5%2F6+is+an+important+mechanism+of+purinergic+receptor-induced+decline+of+cAMP+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence Rumi%28-%2F-%29+embryos+die+before+embryonic+day+9.5+with+posterior+axis+truncation+and+severe+defects+in+neural+tube+development%2C+somitogenesis%2C+cardiogenesis+and+vascular+remodeling. assertion.
- assertion asSentence Loss+of+CIP2A+in+Myc-overexpressing+neural+progenitor+cells+significantly+reduces+the+ability+of+Myc+to+increase+self-renewal+and+proliferation. assertion.
- assertion asSentence CLIC5+disrupts+proliferation+of+C2C12+cells+and+is+involved+in+the+differentiation+of+myoblasts+by+enhancing+the+protein+expression+level+of+MyHC%2C+myogenin+and+desmin. assertion.
- assertion asSentence Expression+of+Dlgap1+in+the+mouse+prefrontal+cortex+is+modulated+by+a+sequence+variant+%28B2+SINE+indel%29+in+the+3%27+UTR+of+Comt+%28catechol-O-methyltransferase%29. assertion.