Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Glypican-1+has+an+important+role+in+peripheral+nerve+terminal+differentiation. assertion.
- assertion asSentence The+ability+of+Gas6+to+prevent+apoptosis+requires+both+Gas6+binding+to+Axl+and+Axl+kinase+activity. assertion.
- assertion asSentence Profound+modifications+of+NR2B+subunit+association+with+synapse-associated+protein+102+occurs+in+6-OHDA%2C+L-DOPA+-treated+dyskinesia. assertion.
- assertion asSentence Activating+transcription+factor+3+%28ATF3%29+promotes+sublytic+C5b-9-induced+glomerular+mesangial+cells+apoptosis+through+up-regulation+of+Gadd45alpha+and+KLF6+gene+expression. assertion.
- assertion asSentence G+protein-coupled+receptor+kinase+2+is+involved+in+corticotropin+releasing+factor-induced+desensitization+by+CRF+receptor+type+1+%28CRFR1+in+a+cell+line. assertion.
- assertion asSentence The+opposing+effects+of+dorsal+raphe+CRF+on+5-HT+release+in+the+nucleus+accumbens+are+dependent+on+differential+activation+of+CRF%281%29+and+CRF%282%29+receptors+in+the+dorsal+raphe+nucleus. assertion.
- assertion asSentence Antagonism+of+CRFR1+selectively+modifies+weight+loss+in+restrained+rats. assertion.
- assertion asSentence The+non-competitive+antagonist+behaviour+appeared+to+be+correlated+to+the+CRF%281%29+receptor+off-rate+kinetics. assertion.
- assertion asSentence CRHR1+does+not+have+a+role+in+basal+alcohol+intake+or+relapse-like+drinking+situations+with+a+low+stress+load. assertion.
- assertion asSentence RAMP1+is+functional+CGRP+receptor+and+receptor+component+in+lungs. assertion.
- assertion asSentence PI3K%2FAKT+signaling+controls+aggrecan+gene+expression%2C+in+part+by+modulating+Sox9+expression+and+activity+in+cells+of+the+nucleus+pulposus. assertion.
- assertion asSentence %28MAFA%29%2C+selectively+regulates+the+Fc-epsilon-RI+stimulus-response+coupling+network+and+the+subsequent+de+novo+production+and+secretion+of+inflammatory+mediators. assertion.
- assertion asSentence TGF-beta1-induced+p38+activation+is+involved+in+TGF-beta1-stimulated+collagen+synthesis. assertion.
- assertion asSentence Interaction+of+TGF-beta%281%29+and+iNOS+plays+a+role+in+the+pathogenesis+of+hypoxia-induced+pulmonary+hypertension. assertion.
- assertion asSentence TGFbeta1+promotes+cell+cycle+exit+in+the+cortical+ventricular+zone+through+modulation+of+cell+cycle+protein+expression%2C+in+particular+cyclin+D1+and+the+cyclin-dependent+kinase+inhibitors+p27+and+p21. assertion.
- assertion asSentence TGF-beta+1+delays+the+G2+transition+into+the+M+%28mitosis%29+phase+of+the+cell+cycle+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence Overexpression+of+decorin+down-regulates+the+expression+of+TGFbeta1+and+extracellular+matrix+components+from+rat+mesangial+cells. assertion.
- assertion asSentence Fluvastatin+can+inhibit+overproduction+of+TGF-beta1+in+glomerular+mesangial+cells+under+high+concentration+of+glucose. assertion.
- assertion asSentence Qufeng+Tongluo+Recipe+has+great+inhibitory+effect+on+mesangial+cell+proliferation+and+expressions+of+TGF-beta1+and+IL-6+mRNAs. assertion.
- assertion asSentence TGF+beta+1+promotes+cell+proliferation+and+cell+cycle+progression+in+rat+nucleus+pulposus+cell+cultures. assertion.
- assertion asSentence A+pyrrole-imidazole+polyamide+targeting+transforming+growth+factor-beta1+inhibits+restenosis+and+preserves+endothelialization+in+the+injured+artery. assertion.
- assertion asSentence Pyrrolidine+dithiocarbamate+attenuate+paraquat-induced+up-regulation+of+TGF-beta%281%29%2C+MMP-2+and+TIMP-1. assertion.
- assertion asSentence Iodine+deficiency+leads+to+the+activation+of+c-Jun+and+TGF-beta1+in+kidney. assertion.
- assertion asSentence TGFbeta1+operates+in+cycling+neuronal+progenitors+through+a+feed-forward+regulatory+system+that+is+pivotally+regulated+at+the+level+of+translation. assertion.
- assertion asSentence TGF-beta1+is+a+potent+inducer+of+arthrofibrosis. assertion.
- assertion asSentence A+higher+dose+of+Liangxuehuoxue+Recipe+produces+more+significant+inhibitory+effects+on+TNF-alpha+and+TGF-beta+expressions+in+the+lung+tissue+of+rats+exposed+to+X-ray+radiation. assertion.
- assertion asSentence By+suppressing+TGF-beta%2FSmad+and+NADPH+activation%2C+grape+seed+extract+attenuates+arsenic-induced+low+antioxidant+defense%2C+oxidative+damage%2C+proinflammatory+cytokines+and+fibrogenic+genes. assertion.
- assertion asSentence A+role+for+TGF-beta1+in+maintaining+RGC-5+cell+survival+and+promoting+neurite+outgrowth+through+p38+MAPK. assertion.
- assertion asSentence TGF-beta+1+and+hyperoxia-mediated+pulmonary+responses+are+mediated%2C+at+least+in+part%2C+via+signaling+through+the+JNK+pathway. assertion.
- assertion asSentence The+upregulation+of+TGF-beta1%2C+Smad2%2F3+and+Smad7+in+liver+tissue+is+involved+in+the+progression+of+hepatic+fibrosis. assertion.
- assertion asSentence Patterns+of+expression+changes+after+renal+ischemia-reperfusion. assertion.
- assertion asSentence Prostaglandin+E+synthase%28PGES%29-1+and+-2+are+colocalized+with+COX-2+in+cardiac+myocytes+and+fibroblasts. assertion.
- assertion asSentence Insulin+receptor-related+receptor+mRNA+is+detected+in+cells+that+also+express+trkA%2C+the+nerve+growth+factor+tyrosine+kinase+receptor+in+the+ovary. assertion.
- assertion asSentence NGF+administration+reverses+the+neuro-glial+morphomolecular+changes+occurring+in+neuropathic+animals+paralleled+by+alterations+in+neurotrophin+receptors+ratio. assertion.
- assertion asSentence SCOP+bound+through+its+LRR+domain+with+a+subset+of+K-ras+in+the+raft+fraction%2C+interfering+with+the+binding+of+added+guanine+nucleotide+to+K-Ras. assertion.
- assertion asSentence The+cytoplasmic+C2+domains+in+synaptotagmin+VII+contain+unique+internalization+signals+and+regulators+of+these+endocytotic+signals. assertion.
- assertion asSentence Intracerebroventricular+injection+of+nesfatin-1+stimulates+the+sympathetic+outflow+to+the+kidney+and+elevated+blood+pressure+in+anesthetized+rats. assertion.
- assertion asSentence Structural+basis+for+the+properties+of+Calnuc+and+NUCB2+binding+to+Galpha+subunits+and+its+regulation+by+calcium+ions. assertion.
- assertion asSentence Bacterial+lipopolysaccharide+increases+gastric+corpus+Nucb2+protein+concentration. assertion.
- assertion asSentence Trisk+95+negatively+regulates+ryanodine+receptor+function+by+suppressing+localized+calcium+release+events+and+global+calcium+signals+in+cultured+muscle+cells. assertion.
- assertion asSentence A+role+of+obestatin+in+the+control+of+beta-cell+secretion. assertion.
- assertion asSentence A+key+role+of+soluble+adenylyl+cyclase+in+simulated+in+vitro+ischaemia+induced+mitochondrial+Bax+translocation+and+activation+of+the+mitochondrial+pathway+of+apoptosis+in+adult+cardiomyocytes. assertion.
- assertion asSentence Expression+of+ErbB2+and+ErbB4+receptor+mRNA+is+down-regulated+in+myocardial+infarction. assertion.
- assertion asSentence NRG1+stimulation+of+the+ErbB4+receptor+exerts+a+sustained+divalent+calcium-ion+increase+in+a+neural+progenitor+cell+line. assertion.
- assertion asSentence The+LHR-stimulated+ERK1%2F2+pathway+stimulates+epiregulin+release. assertion.
- assertion asSentence PKA+and+Epac+cooperatively+enhance+functional+GJ+neoformation+in+cardiomyocytes. assertion.
- assertion asSentence Activation+of+Epac+by+an+exogenous+cAMP+analog+triggers+intracellular+Ca%282%2B%29+mobilization+and+apical+exocytotic+insertion+of+AQP2+in+inner+medullary+collecting+duct. assertion.
- assertion asSentence SIK+isoforms+regulate+hormonal+signal+transduction+in+both+adrenal+and+adipose+tissues. assertion.
- assertion asSentence There+are+both+pro-+and+anti-opioid+actions+of+NPFF+in+the+parabrachial+nucleus+to+modulate+feeding. assertion.
- assertion asSentence High+affinity+interactions+between+the+palmitoyl-oleoyl-phosphatidylglycerol+and+the+Toll-like+receptor+4-interacting+proteins+CD14+and+MD-2. assertion.
- assertion asSentence FXR-mediated+regulation+of+angiotensin+type+2+receptor+expression+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence FXR+plays+an+important+role+in+modulating+the+metabolism+of+bile+acids. assertion.
- assertion asSentence NSF+interaction+is+necessary+for+rapid+incorporation+of+alpha-amino-3-hydroxy-5-methylisoxazolepropionate+%28AMPA%29+receptor+subunits+into+synapses+and+is+sufficient+to+confer+this+property+on+the+AMPA+receptor+GluR3+subunit. assertion.
- assertion asSentence Adenovirus-mediated+stromal+cell-derived-+factor-1alpha+gene+transfer+induces+cardiac+preservation+after+infarction+via+angiogenesis+of+CD133%2B+stem+cells+and+anti-apoptosis. assertion.
- assertion asSentence Posttranslational+arginine+methylation+of+lamin+A%2FC+during+myoblast+fusion. assertion.
- assertion asSentence siRNA+specific+for+TRPC1+and+TRPC3+in+proliferating+cells+inhibited+approximately+the+same+amount+of+Store+operated+calcium+entry. assertion.
- assertion asSentence Distribution+of+Fhit+protein+in+rat+tissues+and+its+intracellular+localization. assertion.
- assertion asSentence Expression+of+SCF%2BGM-CSF+after+hepatectomy+can+contribute+to+biliary+remodeling+%28e.g.%2C+post-transplantation%29+by+functional+deregulation+of+the+activity+of+key+signaling+intermediates+involved+in+cell+expansion+and+multipotent+differentiation. assertion.
- assertion asSentence MLC1+mutations+reduce+protein+levels+in+rat+astrocytes. assertion.
- assertion asSentence Intracellular+zinc+release-activated+ERK-dependent+GSK-3beta-p53+and+Noxa-Mcl-1+signaling+are+both+involved+in+cardiac+ischemic-reperfusion+injury. assertion.
- assertion asSentence Activation+of+the+endogenous+rat+mucosal+GLP-2+receptor+is+linked+to+activation+of+a+cAMP%2Fprotein+kinase+A-dependent%2C+growth-promoting+pathway+in+vitro. assertion.
- assertion asSentence CCR2+mediates+recruitment+of+both+infiltrating+macrophages+and+resident+microglia+to+specific+sites+of+central+nervous+system+inflammation. assertion.
- assertion asSentence Cortactin+and+dynamin-2+co-localize+in+growth+cones+of+embryonic+hippocampal+neurons. assertion.
- assertion asSentence Syt+I+and+Syt+IX+function+redundantly+in+Ca%282%2B%29-sensing+and+fusion+pore+dilation+on+large+dense+core+vesicles+in+PC12+cells. assertion.
- assertion asSentence Developmental+and+steroidogenic+effects+on+the+gene+expression+of+RFamide+related+peptides+and+their+receptor+in+the+rat+brain+and+pituitary+gland. assertion.
- assertion asSentence PKC+is+involved+in+ethanol-induced+MAPK+expression+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence Suppression+of+ACC1+activity+impairs+glucose-stimulated+insulin+secretion+via+inhibition+of+glucose+rather+than+lipid+metabolism. assertion.
- assertion asSentence A+role+for+CXCL12+and+oligodendroglial+CXCR4+receptors+during+developmental+myelination+and+repair+in+demyelinating+diseases+of+the+central+nervous+system. assertion.
- assertion asSentence Demonstrate+a+functional+role+for+CXCL12%2F+CXCR4+signaling+in+bladder+function+in+normal+rats+and+those+with+cyclophosphamide-induced+cystitis. assertion.
- assertion asSentence A+significant+decrease+in+the+levels+of+amphiphysin+1+mRNA+is+found+in+the+hippocampus+of+aged+rats+subjected+to+repeated+variable+stress+compared+with+treated+and+untreated+adult+rats+or+to+untreated+aged+rats. assertion.
- assertion asSentence Per2+gene+expression+in+the+diurnal+degu+%28Octodon+degus%29+differs+from+the+nocturnal+laboratory+rat+%28Rattus+norvegicus%29. assertion.
- assertion asSentence PrRP+increases+the+amplitude+of+the+GABAA+receptor-mediated+inhibitory+postsynaptic+current+in+both+ventrobasal+nucleus+and+reticular+thalamic+nucleus+neurons. assertion.
- assertion asSentence A+specific+requirement+of+cytoplasmic+XIAP+is+demonstrated+for+cell+survival+in+neonatal+rat+brain+following+hypoxia-ischemia. assertion.
- assertion asSentence NMU+selectively+depolarizes+the+subpopulation+of+PVN+parvocellular+neurons+via+enhancement+of+the+hyperpolarization-activated+inward+current. assertion.
- assertion asSentence Neuromedin+U+acts+on+the+presynaptic+terminals+of+the+primary+afferent+fibers+working+as+an+autocrine%2Fparacrine+neuromodulator+to+increase+the+frequency+of+miniature+excitatory+postsynaptic+currents+of+the+substantia+gelatinosa+and+deep+layer+neurones. assertion.
- assertion asSentence Outer+mitochondrial+membrane+cytochrome+b5+and+not+microsomal+membrane+cytochrome+b5+functions+as+an+activator+for+androgenesis+in+rat+Leydig+cells. assertion.
- assertion asSentence Csk+negatively+regulates+growth+factor+induced+neural+differentiation+and+augments+Akt+kinase+activity. assertion.
- assertion asSentence Maximal+TGF-beta+induction+of+CTGF+requires+synergy+between+SMAD+and+ras%2FMEK%2FERK+signaling. assertion.
- assertion asSentence The+in+vitro+and+in+vivo+expression+of+Ctgf+in+osteoblasts+and+in+fractures. assertion.
- assertion asSentence Delivery+of+CTGF+siRNA+via+the+caudal+vein+significantly+inhibited+expression+of+CTGF+in+rat+kidneys%2C+effectively+preventing+fibrosis+in+chronic+allograft+nephropathy+after+kidney+transplantation. assertion.
- assertion asSentence CTGF+plays+a+significant+role+in+the+pathological+changes+of+chronic+allograft+nephropathy+after+kidney+transplantation. assertion.
- assertion asSentence JNK+mediates+the+expression+of+CTGF+and+corneal+scarring+in+corneal+wound+healing. assertion.
- assertion asSentence In+vivo%2C+DAF+is+present+on+glomerular+epithelial+cells+apical+surfaces. assertion.
- assertion asSentence The+presence+of+enzyme+activity+in+subcellular+organelles+in+brain+and+liver+and+in+mitochondria+demonstrates+functional+glutaredoxin+activity. assertion.
- assertion asSentence Dimethylarginine+dimethylaminohydrolase+plays+a+pivotal+role+in+tumour+growth+and+the+development+of+the+tumour+vasculature+by+regulating+the+concentration+of+nitric+oxide+and+altering+vascular+endothelial+cell+growth+factor+production. assertion.
- assertion asSentence Ecstacy%2Fmethamphetamine+trigger+concerted+proteolytic+attacks+on+Spna2+and+tau+proteins+by+calpain+and+caspase+family+of+proteases. assertion.
- assertion asSentence Ascl1+is+required+for+oligodendrocyte+development+in+the+spinal+cord. assertion.
- assertion asSentence Calreticulin+is+a+high+affinity+ligand+of+GABARAP. assertion.
- assertion asSentence The+DG-plectin+complex+plays+a+central+role+in+transmitting+mechanical+stress+from+the+extracellular+matrix+to+the+cytoplasm. assertion.
- assertion asSentence Profilin+is+coordinately+regulated+during+actin+remodeling+in+epithelial+cells. assertion.
- assertion asSentence Blockade+of+caspase+2+activation+prevents+heat-induced+germ+cell+apoptosis+in+rats+by+suppressing+the+MAPK14-+and+NO-mediated+intrinsic+pathway+signaling. assertion.
- assertion asSentence NF-kB+activation+in+PC12+cells+upregulates+IPAS+gene+expression+without+activating+HIF-1a+and+HIF-2a. assertion.
- assertion asSentence CD11d+expression+increased+in+retroperitoneal+white+adipose+tissue+of+Zucker+obese+rats. assertion.
- assertion asSentence Ca%282%2B%29+binding+properties+of+calmodulin+are+highly+regulated+and+there+is+a+role+for+RC3+in+accelerating+the+dissociation+of+Ca%282%2B%29-calmodulin+target+complexes+at+the+end+of+a+Ca%282%2B%29+signal. assertion.
- assertion asSentence NG+is+expressed+by+principal+cells+in+different+neocortical+layers+and+in+the+hippocampus+by+granule+cells+of+the+dentate+gyrus+and+pyramidal+neurons+of+CA1-CA3. assertion.
- assertion asSentence Mutations+in+desmin+have+both+direct+and+indirect+effects+on+the+cytoarchitecture+of+cardiac+myocytes. assertion.
- assertion asSentence Catalytic+mechanism+for+the+hydrolase+reaction+in+which+Asp-142+polarizes+the+catalytic+water+molecule+and+His-106+orients+the+carbonyl+group+of+formyl. assertion.
- assertion asSentence Combined+expression+of+pancreatic+duodenal+homeobox+1+and+islet+factor+1+induces+immature+enterocytes+to+produce+insulin. assertion.
- assertion asSentence Transient+high+expression+of+Dexras1+which+localized+in+apoptotic+neurons+and+pathological+oligodendrocytes+after+spinal+cord+transection. assertion.
- assertion asSentence Acurate+regulation+of+Cdc42+activity+is+crucial+for+proper+equatorial+actin+assembly+and+RhoA+localization+during+cytokinesis+in+epithelial+cells. assertion.