Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+loss+of+ZnT4+in+airway+inflammation+contributes+to+airway+epithelium+vulnerability+in+diseases+such+as+asthma. assertion.
- assertion asSentence Par-4+exhibits+an+antitransforming+capacity+by+antagonizing+p185%28BCR-ABL%29-induced+factor-independent+proliferation+in+hematopoietic+cells. assertion.
- assertion asSentence Under+physiological+conditions%2C+Par-4+self-associates+via+the+C-terminal+domain%2C+forming+a+coiled-coil. assertion.
- assertion asSentence PTZ-induced+seizures+of+the+rats+activates+NMDA+receptors%2C+then+decrease+thimet+oligopeptidase+enzyme+activity+and+immunoreactivity+in+hippocampal+neurons. assertion.
- assertion asSentence ATP+diphosphohydrolase+%28NTPDase+1%2C+Entpd1%29+in+rat+hippocampal+slices+and+effect+of+glutamate+on+the+enzyme+activity+in+different+phases+of+development. assertion.
- assertion asSentence Broad+overlapping+distribution+in+neurons+and+glial+cells+reflects+the+functional+importance+of+ectonucleotidase+actions+in+the+nervous+system. assertion.
- assertion asSentence The+association+of+AC5+with+the+AKAP6+complex+is+required+for+the+regulation+of+cAMP+second+messenger+controlling+cardiac+myocyte+hypertrophy. assertion.
- assertion asSentence Heparanase+gene+is+involved+in+heparan+sulfate+proteoglycans+metabolism. assertion.
- assertion asSentence Sec14l3+expression+is+highly+and+inversely+associated+with+the+progression+of+airway+inflammation. assertion.
- assertion asSentence Induction+of+Bim+in+NGF-deprived+cells+requires+expression+and+activity+of+cyclin-dependent+kinase+4+and+consequent+de-repression+of+E2+promoter. assertion.
- assertion asSentence The+association+of+AC5+with+the+AKAP6+complex+is+required+for+the+regulation+of+cAMP+second+messenger+controlling+cardiac+myocyte+hypertrophy. assertion.
- assertion asSentence Wnt5a+is+essential+for+normal+prostate+development+where+it+regulates+bud+outgrowth%2C+ductal+elongation%2C+branching%2C+cell+polarity+and+lumenization. assertion.
- assertion asSentence Expression+of+Wnt1+and+Wnt5a+is+related+to+malignant+transformation+and+conversion+of+oral+mucosa. assertion.
- assertion asSentence A+two+order+of+magnitude+species+difference+in+potency+of+alpha-conotoxin+RgIA+for+rat+versus+human+alpha9alpha10+nAChR. assertion.
- assertion asSentence Cullin-5+mRNA+levels+are+significantly+increased+in+the+rat+cerebral+cortex%2C+hypothalamus+and+kidney+following+48+h+of+water+deprivation. assertion.
- assertion asSentence Translocation+of+full+Length-Bid+is+sufficient+for+the+activation+of+mitochondrial+cell+death+pathways+in+response+to+glutamate+receptor+overactivation. assertion.
- assertion asSentence Glioma+cells+treated+with+cannabinoids+undergo+apoptosis+and+down+regulation+of+bad+protein. assertion.
- assertion asSentence Sex+differences+in+the+response+of+MCH+neurons+to+glucose+correlated+well+with+the+gonadal+steroid+milieu. assertion.
- assertion asSentence The+nNOS-PMCA4b+complex+regulates+contractility+via+cAMP+and+phosphorylation+of+both+PLB+and+cTnI. assertion.
- assertion asSentence The+SRD5A2+mRNA+expression+in+normal+rat+is+4-fold+higher+than+human+prostatic+tissue. assertion.
- assertion asSentence Binge-like+ethanol+intake+in+C57BL%2F6J+mice+is+modulated+by+CRF%281%29R+and+CRF%282%29R+signaling%2C+such+that+blockade+of+CRF%281%29R+or+activation+of+CRF%282%29R+effectively+reduces+excessive+ethanol+intake. assertion.
- assertion asSentence The+pseudo+signal+peptide+of+the+corticotropin-releasing+factor+receptor+type+2a+decreases+receptor+expression+and+prevents+Gi-mediated+inhibition+of+adenylyl+cyclase+activity. assertion.
- assertion asSentence Consequences+of+CK2+signaling+to+the+nuclear+matrix. assertion.
- assertion asSentence Epoxide+hydrolase+inhibitors+displays+antihypertensive+effects+in+Ren-2+transgenic+rats+with+inducible+malignant+hypertension+via+an+improvement+of+renal+function. assertion.
- assertion asSentence In+glomerulosa+cells+activation+of+native+5-HT%287%29+receptors+stimulates+cAMP+formation+through+a+G%28salpha%29+protein+and+calcium+influx+through+T-type+calcium+channels. assertion.
- assertion asSentence A+deletion+in+the+Mer+tyrosine+kinase+%28MerTK%29+receptor+in+Royal+College+of+Surgeons+rat+that+abolishes+internalization+of+photoreceptor+outer+segments+by+retinal+pigment+epithelial+cells. assertion.
- assertion asSentence The+p110delta+isoform+of+PI3-kinase+is+implicated+in+arterial+hyperresponsiveness+in+hypertension+at+the+level+of+both+large+and+small+arteries. assertion.
- assertion asSentence Inhibition+of+PI+3-K%2FAkt+signaling+pathway+induces+apoptosis+in+rat+hepatic+stellate+cells+%28HSC%29. assertion.
- assertion asSentence Claudin-6+is+a+transmembrane+protein+of+tight+junctions+in+podocytes+during+development+and+under+pathological+conditions. assertion.
- assertion asSentence Hemorrhagic+shock+causes+an+acute+rise+in+serum+claudin-3+protein+levels+and+a+concurrent+decrease+in+intestinal+claudin-3+protein+expression. assertion.
- assertion asSentence Ethanol+treatment+induces+ALAS1+gene+expression. assertion.
- assertion asSentence Hypoxia+leads+to+stabilization+of+D2+by+slowing+its+degradation+by+the+proteasome+pathway. assertion.
- assertion asSentence SCAMP+isoforms+regulate+membrane+fusion+and+dense+core+vesicle+exocytosis+in+neurons. assertion.
- assertion asSentence Zinc-mediated+tetramerization+also+is+a+physiologically+important+event+for+full-length+functional+channel+formation. assertion.
- assertion asSentence Increased+extracelluar+signal-regulated+kinase+%28ERK%29+phosphorylation+of+Kv4.2+and+decreased+levels+of+Kv4.2+channels+in+the+post-synaptic+membrane+of+hippocampal+neurons+contribute+to+hyperexcitability+during+status+epilepticus. assertion.
- assertion asSentence Interaction+between+transcription+factors+Iroquois+proteins+4+and+5+controls+cardiac+potassium+channel+Kv4.2+gene+transcription+across+the+left+ventricular+wall+of+rodent+hearts. assertion.
- assertion asSentence In+response+to+an+increase+of+cellular+cholesterol%2C+fatty+acid+transporter+is+translocated+from+cytosol+to+membranes+of+type+II+pneumocytes. assertion.
- assertion asSentence The+expression+densities+of+Kv4.2+and+Kv4.3+channels+are+significantly+higher+in+type+I+neurons+than+in+type+II+neurons. assertion.
- assertion asSentence Cardiomyocyte+endosomes+control+channel+kv4.3+mRNA+expression+by+mediating+delayed+oxidative+CamKII-p38K+signaling. assertion.
- assertion asSentence Modafinil+inhibits+K%28Ca%293.1+channels+and+vascular+smooth+muscle+contraction+by+cAMP-dependent+phosphorylation. assertion.
- assertion asSentence Activation+of+AMPK+alpha1+and+alpha2+play+both+sufficient+and+necessary+role+in+stimulation+of+glucose+transport+in+response+to+inhibition+of+oxidative+phosphorylation. assertion.
- assertion asSentence Hindbrain+AMPK+activity+contributes+to+energy+balance+control+through+regulation+of+food+intake+and+energy+expenditure. assertion.
- assertion asSentence Alterations+in+AMPK+pathway+in+the+liver+induced+metabolic+defects+associated+with+lipid+oversupply. assertion.
- assertion asSentence The+inhibitory+effects+of+metformin+on+fatty+acid+metabolism+occur+via+preferential+phosphorylation+of+AMPK-alpha%281%29. assertion.
- assertion asSentence Adiponectin+reduces+Kiss1+gene+transcription+in+GT1-7+cells+through+activation+of+AMPK+and+subsequently+decreased+translocation+of+SP1. assertion.
- assertion asSentence Agonist-induced+inhibition+of+TREK-2+via+muscarinic+M%283%29+receptor+occurs+primarily+via+PKC-mediated+phosphorylation. assertion.
- assertion asSentence FGF-20+promotes+the+differentiation+of+Nurr1-neural+stem+cells+into+tyrosine+hydroxylase-positive+neurons+and+additional+factors+are+required+for+the+efficient+differentiation+of+dopaminergic+neurons+in+the+adult+brain. assertion.
- assertion asSentence Involved+in+cell+cycle%2C+cell+differrentiation+and+cell+division+of+the+digestive+system+and+digestive+neoplasms. assertion.
- assertion asSentence Ang+II-induced+increases+in+NAD%28P%29H+oxidase+activity%2C+neuronal+ROS+production%2C+%26+dipsogenic+%26+pressor+responses+are+attenuated+by+inhibition+of+NAD%28P%29H+oxidase+by+gp91ds-tat. assertion.
- assertion asSentence Mechanical+stretch+and+angiotensin+II+synergistically+increase+NADPH+oxidase+expression+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence TGF-beta1+increased+both+the+activity+of+NADPH+oxidase+and+expression+of+Nox2+and+Nox4%2C+homologs+of+the+NAD%28P%29H+oxidase+family. assertion.
- assertion asSentence Reactive+oxygen+species+can+be+beneficial+to+the+cell+and+support+a+crucial+role+for+NOX2-derived+ROS+in+cell+survival+in+the+heart. assertion.
- assertion asSentence Neuropeptide+Y2+receptor+is+found+mostly+in+granule+cells+of+the+internal+granule+cell+layer+of+the+cerebellum+during+postnatal+development. assertion.
- assertion asSentence The+expression+of+LPA1+and+LPA3+in+rat+aortic+smooth+muscle+cells. assertion.
- assertion asSentence TRPV4+channels+in+primary+urothelial+cell+cultures+induce+ionic+currents+and+changes+in+intracellular+calcium. assertion.
- assertion asSentence Wild-type+and+brachyolmia-causing+mutant+TRPV4+channels+respond+directly+to+stretch+force. assertion.
- assertion asSentence Despite+the+high+level+of+sequence+homology+within+the+small+heat-shock+proteins+%28sHSPs%29+family+the+biochemical+properties+of+the+HSPB2%2FB3+complex+are+distinctly+different+from+those+of+other+sHSPs. assertion.
- assertion asSentence Nav1.7+is+the+dominant+sodium+channel+in+rat+and+mouse+olfactory+sensory+neurons. assertion.
- assertion asSentence The+oxidative+stress+and+nonalcoholic+fatty+liver+disease+via+SREBP-1c. assertion.
- assertion asSentence Flt-1+expression+influences+apoptotic+susceptibility+of+vascular+smooth+muscle+cells+through+the+NF-kappaB%2FIAP-1+pathway. assertion.
- assertion asSentence Skeletal+muscle+AMPK+subunit+expression+is+partially+under+the+control+of+thyroid+hormones. assertion.
- assertion asSentence Heart+AMP-activated+protein+kinase+is+activated+by+long-chain+fatty+acids. assertion.
- assertion asSentence AMP-activated+protein+kinase+coordinates+the+transition+of+hepatic+lipid+metabolism+in+the+starved+rat+when+it+is+refed. assertion.
- assertion asSentence Finally%2C+cold+exposure+significantly+impaired+insulin-induced+inhibition+of+AMPK+through+a+mechanism+dependent+on+the+molecular+cross-talk+between+phosphatidylinositol-3%28PI3%29-kinase%2FAkt+and+AMPK. assertion.
- assertion asSentence A+central+role+for+neuronal+adenosine+5%27-monophosphate-activated+protein+kinase+in+cancer-induced+anorexia. assertion.
- assertion asSentence In+liver%2C+AMPK+activation+repressed+translation+of+5%27-terminal+oligopyrimidine+tract+mRNAs+through+a+mechanism+distinct+from+downregulated+phosphorylation+of+S6K1+or+rpS6. assertion.
- assertion asSentence AMP-activated+protein+kinase+confers+protection+against+TNF-%7Balpha%7D-induced+cardiac+cell+death. assertion.
- assertion asSentence Globular+adiponectin+inhibits+cardiac+hypertrophic+signaling+through+AMPK+mediated+suppression+of+NF-kappaB+activation. assertion.
- assertion asSentence Along+with+MAPK%2C+AMPK+signaling+also+plays+a+crucial+role+in+the+progression+of+experi-mental+autoimmune+myocarditis. assertion.
- assertion asSentence KiSS-1+and+GPR54+genes+are+co-expressed+in+rat+gonadotrophs+and+differentially+regulated+in+vivo+by+oestradiol+and+gonadotrophin-releasing+hormone. assertion.
- assertion asSentence Ref-1+expression+increased+in+the+after+hippocampus+CA1+area+after+induction+of+Alzheimer%27s+disease. assertion.
- assertion asSentence RalA+controls+exocytosis+of+large+dense+core+secretory+granules+by+interacting+with+ARF6-dependent+phospholipase+D1. assertion.
- assertion asSentence ASIC1a+expression+in+hippocampus+is+increased+by+chronic+lead+exposure. assertion.
- assertion asSentence Asn415+in+the+beta11-beta12+linker+decreases+proton-dependent+desensitization+of+ASIC1. assertion.
- assertion asSentence Enhanced+expression+of+p22phox+contributes+to+augmented+VSMC+proliferation+in+diabetic+rats. assertion.
- assertion asSentence Chronic+intermittent+hypoxia+upregulates+the+expression+of+p22phox+in+rat+carotid+body+and+elevates+the+rat+systolic+blood+pressure. assertion.
- assertion asSentence V-1+expression+is+increased+by+hypertension+in+DS+rat+atrium. assertion.
- assertion asSentence Modulation+of+Cx46+hemichannels+by+nitric+oxide. assertion.
- assertion asSentence The+expression+of+HSP70+and+HSF1+markedly+increase+in+intestinal+mucosa+following+severe+burn+injury. assertion.
- assertion asSentence More+than+half+of+all+ganglion+neurons+that+project+to+the+masseter+or+temporalis+muscle+express+the+5-HT3+receptor. assertion.
- assertion asSentence 5-HT%283%29+receptors+possess+a+role+of+dual+regulation+on+electrolyte+secretion+in+rat+distal+colon%2C+the+neural+stimulatory+effect+of+5-HT%283%29+receptor+in+myenteric+plexus+and+the+inhibitory+effect+of+5-HT%283%29+receptor+in+submucosal+plexus. assertion.
- assertion asSentence ASPA+colocalized+throughout+the+brain+with+CC1%2C+a+marker+for+oligodendrocytes%2C+with+92-98%25+of+CC1-positive+cells+also+reactive+with+the+ASPA+antibody. assertion.
- assertion asSentence ATF4+overexpression+in+nucleus+accumbens+decreases+emotional+reactivity+and+increases+depression-like+behavior. assertion.
- assertion asSentence p38+MAPK+activation+and+phorbol+ester+upregulated+AUF1+expression+in+cultured+cardiac+cells. assertion.
- assertion asSentence The+expression+of+SCDGF%2FPDGF-C%2Ffallotein+and+SCDGF-B%2FPDGF-D+in+the+rat+central+nervous+system. assertion.
- assertion asSentence ATII+induction+of+PDGF-C+transcription+is+mediated+by+the+angiotensin+type+1+receptor+and+through+an+Egr-1-binding+element+in+the+PDGF-C+promoter. assertion.
- assertion asSentence In+sustained+endotoxemia%2C+ALS+levels+are+regulated+through+modulation+of+hepatic+insulin+sensitivity. assertion.
- assertion asSentence Insulin-deficiency+in+insulin-dependent+diabetes+mellitus+decreases+osteoblastogenesis+associated+with+inhibition+of+Wnt+signaling+through+the+increased+expression+of+Sost+and+Dkk1+and+the+inhibition+of+Akt+activation. assertion.
- assertion asSentence In+the+pancreatic+beta-cell%2C+tomosyn+negatively+regulates+insulin+exocytosis. assertion.
- assertion asSentence Islet+cell+autoantigen+69+kDa+%28ICA69%29+regulates+AMPA+receptor+trafficking+by+preventing+formation+of+homomeric+protein+interacting+with+C+kinase+1+%28PICK1%29+Bin%2Famphiphysin%2FRvs+%28BAR%29+domain+complexes. assertion.
- assertion asSentence Following+cecal+ligation+and+puncture+CINC-1+production+increases+in+the+lung%2C+setting+the+stage+for+neutrophil+accumulation+in+lung+during+sepsis. assertion.
- assertion asSentence Severe+burn+injury+activates+pulmonary+NF-kappaB+and+leads+to+secretion+of+IL8+and+TNF+alpha+in+the+lung. assertion.
- assertion asSentence Advanced+glycation+end+products+promote+the+secretion+of+MCP-1+and+IL-8+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence Activation+of+Ezrin%2FRadixin%2FMoesin+proteins+at+the+Schwann+cell+process+tip+is+essential+for+motility+and+the+maintenance+of+polarity. assertion.
- assertion asSentence CCN3+suppresses+neointimal+thickening+through+the+inhibition+of+vascular+smooth+cell+migration+and+proliferation. assertion.
- assertion asSentence Y80+and+D117+are+required+for+the+communication+between+the+dichloroacetate-binding+site+and+active+site+of+PDK2. assertion.
- assertion asSentence Mobility+of+adenosine+triphosphate+%28ATP%29+lid+is+central+to+allosteric+regulation+of+pyruvate+dehydrogenase+kinase-2+activity+serving+as+a+conformational+switch+required+for+communication+between+active+site+and+allosteric+sites+in+the+kinase+molecule. assertion.
- assertion asSentence An+important+mechanism+of+electroacupuncture+therapy+is+its+regulation+of+Nav1.6+and+Nav1.1+expression+after+ischemia. assertion.
- assertion asSentence CEACAM1+influences+the+resolution+of+inflammation+by+prolonging+the+survival+of+rat+granulocytes. assertion.
- assertion asSentence Insulin+acutely+reduces+hepatic+FAS+activity+by+inducing+phosphorylation+of+the+carcinoembryonic+antigen-related+cell+adhesion+molecule+1+%28CEACAM1%29+and+its+interaction+with+FAS. assertion.