Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Differential+expression+of+secreted+frizzled-related+protein+4+in+decidual+cells+during+pregnancy. assertion.
- assertion asSentence Cyclic+stretch+increased+Tie2+in+coronary+microvascular+endothelial+cells. assertion.
- assertion asSentence Enhanced+expression+of+Ang-1+and+Tie-2+by+exercise+improves+recovery+of+brain+function+in+middle+cerebral+artery+occluded+rats. assertion.
- assertion asSentence Enhanced+expression+of+Ang-1+and+Tie-2+by+exercise+improves+recovery+of+brain+function+in+middle+cerebral+artery+occluded+rats. assertion.
- assertion asSentence Assessment+of+expression+in+chronic+allograft+nephropathy. assertion.
- assertion asSentence Autologous+implantation+of+nucleus+pulposus+induces+hyperalgesia+and+allodynia%2C+leading+to+upregulation+of+fractalkine+and+its+receptor+in+spinal+neurons+and+glia%2C+implicating+fractalkine+in+association+with+radicular+pain. assertion.
- assertion asSentence SH2B1beta+enhances+FGF1-induced+neurite+outgrowth+in+PC12+cells+mainly+through+MEK-ERK1%2F2-STAT3-Egr1+pathway. assertion.
- assertion asSentence siRNA+specific+for+TRPC1+and+TRPC3+in+proliferating+cells+inhibited+approximately+the+same+amount+of+Store+operated+calcium+entry. assertion.
- assertion asSentence TRPC1+associates+with+BK%28Ca%29+channel+to+form+a+signal+complex+in+vascular+smooth+muscle+cells. assertion.
- assertion asSentence STIM1+together+with+TRPC1+plays+a+pivotal+role+as+a+functional+regulator+of+cardiac+hypertrophy. assertion.
- assertion asSentence STIM1+physically+interacts+with+TRPC1+in+IECs+and+the+formation+of+STIM1%2FTRPC1+complex+is+necessary+for+the+activation+of+TRPC1+channels+during+restitution+after+wounding. assertion.
- assertion asSentence TRPC6+expression+is+significantly+down-regulated+in+rat+cerebellum+during+6+weeks+after+birth.Expression+is+found+on+Purkinje+cell+bodies%2C+on+mature+granule+cells+in+internal+granule+cell+layer+%28but+not+their+precursors%29+%26+interneurons+in+molecular+layer. assertion.
- assertion asSentence Phosphorylation+and+functional+suppression+of+TRPC6+underlie+prevention+of+pathological+hypertrophy+by+PDE5+inhibition. assertion.
- assertion asSentence H%282%29O%282%29+activates+TRPC6+channels+via+modification+of+thiol+groups+of+intracellular+proteins. assertion.
- assertion asSentence The+deleterious+effects+of+AngII+on+podocytes+and+its+pathogenic+role+in+glomerular+disease+involve+enhanced+TRPC6+expression+via+a+calcineurin%2FNFAT+positive+feedback+signaling+pathway. assertion.
- assertion asSentence SOCS-3+participates%2C+as+a+late+event%2C+in+the+negative+cross-talk+between+angiotensin+II+and+insulin%2C+producing+an+inhibitory+effect+on+insulin-induced+glucose+transporter-4+translocation. assertion.
- assertion asSentence SOCS-3%2C+induced+by+a+cAMP+stimulant+and+IL-6%2C+would+be+involved+in+the+negative+regulation+of+CRF+gene+expression+in+hypothalamic+cells. assertion.
- assertion asSentence High-fat+feeding+increases+insulin+receptor+and+IRS-1+coimmunoprecipitation+with+SOCS-3%2C+IKKalpha%2Fbeta+phosphorylation+and+decreases+PI-3+kinase+activity+in+muscle. assertion.
- assertion asSentence Noradrenaline+acting+at+central+beta-adrenoceptors+induces+Socs3+expression+in+rat+brain. assertion.
- assertion asSentence Phosphorylation+inhibits+tubulin+polymerization+in+microtubules. assertion.
- assertion asSentence PLGF+expression+in+the+lung+tissue+in+rats+with+paraquat-induced+pulmonary+fibrosis+is+upregulated. assertion.
- assertion asSentence Endothelin-converting+enzyme-1+expression+is+enhanced+in+acute+hypoxic+rat+aorta. assertion.
- assertion asSentence Amiodarone+acutely+inhibits+vascular+activity+of+endothelin-converting+enzymes. assertion.
- assertion asSentence Mechanical+stretch+regulates+endothelin-converting+enzyme-1beta+gene+expression+in+cardiac+myocytes+and+fibroblasts. assertion.
- assertion asSentence Kir7.1+is+involved+in+the+development+of+renal+K%2B+excretion+between+14+and+21+days+after+birth+under+the+condition+of+K%2B+overload. assertion.
- assertion asSentence Constitutive+activation+of+the+NRG-1%2FerbB+signaling+pathway+is+an+alternative+means+of+inducing+Schwann+cell+neoplasia. assertion.
- assertion asSentence A+role+for+non-canonical+NRG1+and+ERBB4-4ICD+signaling+in+the+regulation+of+gene+expression+contributes+to+normal+and+schizophrenic+neuronal+function. assertion.
- assertion asSentence Prdx5+overexpression+attenuated+injury+to+small-for-size+liver+transplants+and+increased+survival+in+recipients. assertion.
- assertion asSentence Zuogui+pill+and+Yougui+pill+can+prevent+axonal+injury+and+promote+the+axonal+regeneration+by+increasing+the+expression+of+NGF+and+reduce+the+expression+of+Nogo+A+and+its+receptor. assertion.
- assertion asSentence COUP-TFII+gene+expression+is+repressed+by+secreted+insulin+in+response+to+glucose+through+Foxo1+signaling+and+this+negative+glucose+effect+involves+ChREBP+expression. assertion.
- assertion asSentence Agonists+induce+PHI-1+phosphorylation+in+VSMCs+and+divergent+kinase+signaling+couples+agonist+stimulation+to+PHI-1+and+CPI-17+phosphorylation. assertion.
- assertion asSentence Chronic+activation+of+neutral+ceramidase+protects+beta-cells+against+cytokine-induced+apoptosis. assertion.
- assertion asSentence MiR-30+family+members+inhibit+mitochondrial+fission+through+targeting+p53+and+the+dynamin-related+protein-1+pathway. assertion.
- assertion asSentence The+Drp1+is+required+for+the+release+of+endonuclease+G+from+mitochondria. assertion.
- assertion asSentence Mapping+of+ATP-gated+domains+in+the+transmembrane+segments+of+the+P2X2+receptor. assertion.
- assertion asSentence P2X+receptor+signaling+inhibits+BDNF-mediated+spiral+ganglion+neuron+development+in+the+neonatal+rat+cochlea. assertion.
- assertion asSentence miR-143+specifically+binds+to+the+3%27-untranslated+region+of+versican+mRNA. assertion.
- assertion asSentence In+adult+skeletal+muscle+fibres%2C+the+presence+of+a+functional+t-tubule+network+increases+the+sensitivity+of+RyR1+to+agonists+via+a+mechanism+that+involves+binding+of+Ca2%2B+to+an+extracellular+regulatory+site. assertion.
- assertion asSentence The+amount+of+MT%281%29+receptor+protein+decreased+significantly+in+myocardial+infarction+left+ventricles+compared+with+control+LVs+1+day+after+infarction+%28P+%3C+0.01%29%2C+followed+by+recovery+during+the+next+2+wk. assertion.
- assertion asSentence An+important+role+for+the+DNA+damage+response+mediated+by+ATR-Chk2+in+p53+activation+and+renal+cell+apoptosis+during+cisplatin+nephrotoxicity. assertion.
- assertion asSentence In+utero+exposure+to+flutamide+decreases+expression+levels+of+Insl3+particularly+at+15+days+post+conception. assertion.
- assertion asSentence Involved+in+superoxide+formation+in+renovascular+hypertensive+rats. assertion.
- assertion asSentence The+pulmonary+circulation+is+a+target+for+diabetes-induced+endothelial+dysfunction+via+enhanced+NADPH+oxidase-derived+superoxide+production. assertion.
- assertion asSentence AT+and+AT+receptors%2C+NAD%28P%29H+oxidase+and+PKC+pathway+are+involved+in+the+regulation+of+hydromineral+metabolism+and+antioxidant+enzyme+activity+induced+by+angiotensin+II. assertion.
- assertion asSentence An+increase+of+NADPH+oxidase-1+in+hippocampus+follows+anxiety-like+behavior+and+adjuvant+arthritis. assertion.
- assertion asSentence Both+ET-1+activation+of+ET%28A%29%2FNADPH+oxidase+pathway+and+diminished+antioxidants+critically+contribute+to+epithelial+progenitor+cells+reduction+and+dysfunction+via+increased+oxidative+stress+in+salt-sensitive+hypertension. assertion.
- assertion asSentence Increased+expression+of+Nox1+in+neointimal+smooth+muscle+cells+promotes+activation+of+matrix+metalloproteinase-9. assertion.
- assertion asSentence Slfn-3+plays+a+critical+role+in+regulating+intestinal+mucosal+differentiation. assertion.
- assertion asSentence The+mechanism+of+activating+the+dormant+stem+cell+properties+in+Muller+cells+involves+Wnt+and+Notch+pathways. assertion.
- assertion asSentence Functional+damage+of+the+dystroglycan+complex+is+linked+with+structural+changes+in+the+glomerular+basement+membrane. assertion.
- assertion asSentence Brn-3a+activates+transcription+of+anti-apoptotic+genes+in+retinal+ganglion+cells. assertion.
- assertion asSentence Brn-3a+mRNA+transcription+level+significantly+decreased+in+neural+cells+from+cerebral+hippocampus+in+all+lead+treatment+groups+compared+with+the+control+group. assertion.
- assertion asSentence Sp1+has+a+role+in+increasing+the+expression+of+KLF4+in+phenotypically+modulated+smooth+muscle+cells. assertion.
- assertion asSentence ATRA+induces+KLF4+acetylation+by+p300+and+increases+the+ability+of+KLF4+to+transactivate+the+mfn-2+promoter+in+VSMCs. assertion.
- assertion asSentence TGF-beta1+downregulates+AT1+receptor+expression+via+PKC-delta-mediated+Sp1+dissociation+from+KLF4+and+Smad-mediated+PPAR-gamma+association+with+KLF4. assertion.
- assertion asSentence ERK5+activation+enhances+mesangial+cell+viability+and+collagen+matrix+accumulation+in+rat+progressive+glomerulonephritis. assertion.
- assertion asSentence NFIL3+is+a+general+feed-forward+repressor+of+basic+leucine+zipper+transcription+factors+that+control+neurite+outgrowth. assertion.
- assertion asSentence Myotubes+contained+both+the+p47phox+and+gp91phox+phagocytic+NAD%28P%29H+oxidase+subunits%2C+as+revealed+by+immunodetection. assertion.
- assertion asSentence Up-regulation+of+p47phox+is+involved+in+glycated+albumin-mediated+activation+of+NADPH+oxidase%2C+leading+to+induced+expression+of+TGF-beta+and+extracellular+matrix+proteins+in+mesangial+cells+and+contributing+to+the+development+of+diabetic+nephropathy. assertion.
- assertion asSentence PI4KIIalpha+plays+a+role+in+the+exocytotic+process+downstream+of+Ca%282%2B%29+signaling+in+antigen-mediated+mast+cell+activation. assertion.
- assertion asSentence Arhgef7-specific+siRNA+treatment+significantly+inhibited+Angiotensin+II+-induced+vascular+smooth+muscle+cell+migration. assertion.
- assertion asSentence MEK+inhibition+restores+NIS+protein+levels+and+NIS-mediated+radioiodide+uptake+activity+in+RET%2FPTC+oncogene-transformed+thyroid+cells. assertion.
- assertion asSentence PLC+epsilon+down-regulates+regulation+of+integrin+activation+via+an+independent+H-ras+signaling+pathway. assertion.
- assertion asSentence 1alpha-hydroxylase+is+expressed+in+adipose+tissue+and+is+functional+in+cultured+adipocytes. assertion.
- assertion asSentence Insulin+resistance+induced+by+long-term+beta-adrenergic+stimulation+inhibited+insulin-evoked+expression+of+MKP-1+by+impairing+insulin-induced+phosphorylation+of+both+ERK1%2F2+and+JNK+without+affecting+Akt+kinase+activity. assertion.
- assertion asSentence Induction+of+mitogen-activated+protein+kinase+phosphatase+1+%28MKP-1%29+by+perifused+thyrotropin-releasing+hormone+%28TRH%29+stimulation+in+rat+pituitary+GH3+cells. assertion.
- assertion asSentence Induction+of+MAP+kinase+phosphatase+%28MKP%29-1+activity+by+15-deoxy-delta12%2C14-prostaglandin+J2+%2815d-PGJ2%29+involves+the+inhibitory+action+of+15d-PGJ2+on+monocyte+chemoattractant+protein-1+in+attenuating+inflammatory+brain+disease. assertion.
- assertion asSentence Ca%28v%293.2+T-type+Ca%282%2B%29+channels+in+sensory+neurons+are+upregulated+and+activated%2Fsensitized+by+cystathionine-gamma-lyase-derived+endogenous+H%282%29S+after+spinal+nerve+injury%2C+contributing+to+the+maintenance+of+neuropathic+pain. assertion.
- assertion asSentence Fg+binding+to+endothelial+cells+%28ECs%29+alters+expression+of+actin-associated+endothelial+tight+junction+proteins. assertion.
- assertion asSentence Taurine+supplementation+of+low-protein+diet+rats+restored+Ach-M3R%2C+Synt1%2C+SNAP-25+protein+levels+and+increased+sarcoendoplasmatic+reticulum+Ca2%2B-ATPase+%28SERCA%29+3+protein+expression+in+rats+on+a+low-protein+diet. assertion.
- assertion asSentence Both+interstitial+and+endovascular+rat+trophoblast+cells+synthesize+Prlpm. assertion.
- assertion asSentence The+kidney-specific+WNK1+isoform+suppresses+thiazide-sensitive+Na-Cl+cotransport+through+the+inhibition+of+full+length+WNK1+activity. assertion.
- assertion asSentence HSN2+is+a+nervous+system-specific+exon+of+the+WNK1+gene+%28WNK1%2FHSN2+isoform%29. assertion.
- assertion asSentence The+levels+of+ARMS%2FKidins220+can+be+regulated+by+neuronal+activity+and+calpain+action+to+influence+synaptic+function. assertion.
- assertion asSentence NO+by+induction+of+the+Smad+signaling+pathway+modulates+TIMP-1+expression. assertion.
- assertion asSentence The+expression+levels+of+MMP-9+and+TIMP-1+relate+closely+to+the+disruption+of+renal+tubular+epithelial-myofibroblast+transdifferentiation. assertion.
- assertion asSentence Shear+stress-induced+Ets-1+modulates+TIMP-1+expression+in+microvascular+endothelial+cells. assertion.
- assertion asSentence Atorvastatin+inhibits+the+synthesis+and+release+of+MMP-9+and+TIMP-1+in+the+lung+tissue+of+rats+with+bleomycin-induced+pulmonary+fibrosis. assertion.
- assertion asSentence Unbalanced+MMP%2FTIMP-1+expression+and+excessive+gelatinolytic+activity+contribute+to+paraquat-induced+pulmonary+fibrosis. assertion.
- assertion asSentence An+increase+of+extracellular+H%2B+induces+JNK+phosphorylation+and+c-Jun+expression+via+partly+extracellular+Ca2%2B+influx+through+voltage-gated+Ca2%2B+channels. assertion.
- assertion asSentence JNK1+phosphorylation+of+MAP2+plays+an+important+role+in+defining+dendritic+architecture+in+the+brain. assertion.
- assertion asSentence Rac+acts+downstream+of+integrins+and+growth+factors+to+promote+neuronal+survival+by+repressing+c-Jun%2FBim-mediated+mitochondrial+apoptosis. assertion.
- assertion asSentence Insulin+resistance+induced+by+long-term+beta-adrenergic+stimulation+inhibited+insulin-evoked+expression+of+MKP-1+by+impairing+insulin-induced+phosphorylation+of+both+ERK1%2F2+and+JNK+without+affecting+Akt+kinase+activity. assertion.
- assertion asSentence JNK+regulates+both+LHbeta+and+FSHbeta+transcription+in+a+differential+manner. assertion.
- assertion asSentence Activation+of+c-Jun+N-terminal+kinase+%28JNK%29+plays+an+essential+role+in+nerve+growth+factor+enhancement+of+Ca2%2B-evoked+release+in+PC12+neuroendocrine+cells. assertion.
- assertion asSentence Apoptosis+of+cultured+astrocytes+induced+by+the+copper+and+neocuproine+complex+through+oxidative+stress+and+JNK+activation. assertion.
- assertion asSentence Examine+role+of+myocardial+and+intestinal+JNK1%2FMAPK8+in+remote+vs.+ischemic+preconditioning. assertion.
- assertion asSentence Nanosilver+acts+through+ROS+and+JNK+to+induce+apoptosis+via+the+mitochondrial+pathway. assertion.
- assertion asSentence There+is+cross-talk+between+the+calcineurin+and+JNK+pathway+in+controlling+renovascular+hypertension-induced+cardiac+hypertrophy. assertion.
- assertion asSentence The+inhibition+of+Rho-kinase+reduced+cell+apoptosis+in+I%2FR+in+vivo+via+suppression+of+JNK-mediated+AIF+translocation. assertion.
- assertion asSentence Expression+of+P-c-Jun+in+rats+is+increased+during+asthma+airway+remodeling. assertion.
- assertion asSentence NF-kappaB+and+JNK+signaling+are+involved+in+Mrp1+regulation+during+an+HIV-1+associated+inflammatory+response. assertion.
- assertion asSentence Peptidoglycan-induced+IL-6+expression+is+mediated+by+AP-1+activation+through+the+TLR2+and+JNK%2Fc-Jun+pathways+in+microglia. assertion.
- assertion asSentence JNK+MAPK+is+involved+in+the+expression+of+endothelial+cell+adhesion+molecules+in+thermal+injury. assertion.
- assertion asSentence Phosphorylation+of+ATF-2+by+JNK+is+associated+with+retinal+ganglion+cell+death+after+axon+damage. assertion.
- assertion asSentence JNK1+activation+decreases+binding+of+inhibitory+Smad6+to+the+type+I+BMP+receptor. assertion.
- assertion asSentence CNP+is+capable+of+autoregulating+the+expression+of+its+cognate+receptor%2C+type+B+natriuretic+peptide+receptor. assertion.
- assertion asSentence C-SRC+and+ERK+play+a+role+in+acid-induced+activation+of+NHE-3+protein. assertion.
- assertion asSentence The+ERK2+signal+pathway+is+critical+in+angiotensdin+II-dependent+smooth+muscle+endothelial+cell+division. assertion.
- assertion asSentence Prostaglandin+E2+upregulates+EGF-stimulated+signaling+in+mitogenic+pathways+involving+Akt+and+ERK+in+hepatocytes. assertion.