Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence cAMP+stimulates+Ntcp+and+Mrp2+translocation%2C+at+least+in+part%2C+by+activating+nPKCdelta+via+PI3K-dependent+phosphorylation+at+Thr%28505%29. assertion.
- assertion asSentence PKCalpha%2C+PKCdelta+and+PKCepsilon+undergo+transient+upregulation+associated+with+the+accelerated+cardiac+growth+induced+by+pressure+overload+imposed+in+the+very+early+postnatal+period. assertion.
- assertion asSentence PKC+delta+plays+an+important+role+in+the+propagation+of+the+TNFalpha+signal+regulating+stress+kinase+activation+and+ER+stress-mediated+JNK+activation+and+CHOP+induction. assertion.
- assertion asSentence Activation+of+PKC-delta+promotes+tubular+cell+injury+and+death+during+albuminuria. assertion.
- assertion asSentence PKCdelta+activity+causes+smooth+muscle+depolarization+and+vasoconstriction+by+increasing+the+number+of+TRPM4+channels+in+the+sarcolemma. assertion.
- assertion asSentence Duodenal+mucosal+protein+kinase+C-delta+regulates+glucose+production+in+rats. assertion.
- assertion asSentence The+involvement+of+CaSR+in+cardiac+apoptosis+through+the+mitochondrial+pathway+during+ischemia%2Freperfusion+is+related+to+phospho-PKCdelta+translocation+to+the+mitochondria. assertion.
- assertion asSentence TGF-beta1+downregulates+AT1+receptor+expression+via+PKC-delta-mediated+Sp1+dissociation+from+KLF4+and+Smad-mediated+PPAR-gamma+association+with+KLF4. assertion.
- assertion asSentence A+high-capacity+imino+acid+carrier+localized+at+the+small+intestinal+luminal+membrane+that+transports+nutrients+and+amino+acids+and+imino+acids. assertion.
- assertion asSentence The+catalytic+residues+of+the+MTP+beta-subunit+are+positioned+in+the+active+site+similarly+to+those+of+monofunctional+3-ketoacyl-CoA+thiolase. assertion.
- assertion asSentence Huaiqihuang+Granule+can+up-regulate+the+expressions+of+nephrin+and+podocin+in+renal+tissues+of+rats+with+adriamycin-induced+nephrosis. assertion.
- assertion asSentence In+olfactory+epithelium%2C+high+levels+of+expression+of+xenobiotic+transporters+Mrp1%2C+Mrp3%2C+Mrp5%2C+Mdr1a%2C+Oatp2+and+Oat6+are+expressed. assertion.
- assertion asSentence Ca%282%2B%29-ATPases+play+a+role+in+the+control+of+beta-cell+Ca%282%2B%29+homeostasis+and+insulin+secretion. assertion.
- assertion asSentence SPCA1+expression+significantly+increasaed+in+A7r5+vascular+smooth+muscle+cells+cultured+in+high+glucose+%2825.0+mM%29-supplemented+medium+compared+with+normal+glucose+%285.55+mM%29-supplemented+medium. assertion.
- assertion asSentence Exogenous+CO+prevents+transplant-induced+hepatic+ischemia+reperfusion+injury+by+down-regulating+MEK1+activity. assertion.
- assertion asSentence TGFbeta+also+modulates+FAK+protein+levels+in+cultured+rat+IEC-6+intestinal+epithelial+cells+via+ERK+activation. assertion.
- assertion asSentence Upregulation+of+ceramide%2Fsphingosine+1-phosphate+ratio+is+a+critical+event+in+MAO-A-mediated+cardiac+cell+apoptosis. assertion.
- assertion asSentence Thrombin+activation+of+PI3K%2FPDK1%2FAkt+signaling+promotes+cyclin+D1+upregulation+and+retinal+pigment+epithelium+cell+proliferation. assertion.
- assertion asSentence Striking+differences+between+CBP+and+p300+actions+on+glucocorticoid+signaling+in+astrocytes. assertion.
- assertion asSentence SGK1+phosphorylation+of+IkappaB+Kinase+alpha+and+p300+Up-regulates+NF-kappaB+activity+and+increases+N-Methyl-D-aspartate+receptor+NR2A+and+NR2B+expression. assertion.
- assertion asSentence Ilk+is+required+for+laminin-2-induced+oligodendrocyte+cell+spreading+and+CNS+myelination. assertion.
- assertion asSentence The+integrin-linked+kinase+%28ILK%29-+glycogen+synthase+kinase-3beta+%28GSK-3beta%29+pathway+plays+a+key+role+in+regulating+dendrite+formation+in+developing+mammalian+neurons. assertion.
- assertion asSentence Mutation+of+histidine+105+in+the+T1+domain+of+the+potassium+channel+Kv2.1+disrupts+heteromerization+with+Kv6.3+and+Kv6.4. assertion.
- assertion asSentence Calsyntenin-1+links+a+certain+type+of+vesicular+and+tubulovesicular+organelles+to+the+Kinesin-1+motor. assertion.
- assertion asSentence Binding+of+JIP1+and+FEZ1+to+Kinesin-1+is+sufficient+to+activate+the+motor+for+microtubule+binding+and+motility. assertion.
- assertion asSentence The+antioxidant+Trolox+attenuates+mechanical+ventilation-induced+diaphragmatic+atrophy+independent+of+alterations+in+Akt+regulation+of+FoxO+transcription+factors+and+expression+of+MAFbx+or+MuRF-1. assertion.
- assertion asSentence IL-6+increases+MMP-13+gene+expression+by+activation+of+Jak2. assertion.
- assertion asSentence Pulsed+electromagnetic+fields+down-regulate+Mmp13+expression+of+knee+joint+cartilage. assertion.
- assertion asSentence Assessment+of+expression+in+chronic+allograft+nephropathy. assertion.
- assertion asSentence CX3CR1+contributes+to+the+dendritic+cell-endothelial+cell+interaction. assertion.
- assertion asSentence ChREBP+and+SREBP-1+bind+to+the+mtGPAT+distal+promoter. assertion.
- assertion asSentence VGLUT1+localization+%28most+abundant+in+LIII%2FLIV+and+medial+LV+of+sponal+cord%29+is+consistent+with+an+origin+from+cutaneous+and+muscle+mechanoreceptors+and+disappeared+after+rhizotomy. assertion.
- assertion asSentence Shank2+is+positioned+to+coordinate+the+regulated+endocytic+retrieval+and+downregulation+of+Sodium-Phosphate+Cotransporter+Proteins+Type+IIa+in+rat+renal+proximal+tubule+cells. assertion.
- assertion asSentence With+increasing+levels+of+fear%2C+levels+of+gastrin-releasing+peptide+%28Grp%29+are+increased+in+medial+prefrontal+cortex+and+basolateral+amygdala. assertion.
- assertion asSentence Estradiol%2C+working+through+both+ER+alpha+and%2For+GPR30%2C+activates+in+pachytene+spermatocytes+the+rapid+EGFR%2FERK%2Fc-Jun+pathway%2C+modulating+the+expression+of+genes+involved+in+the+balance+between+cellular+proliferation+and+apoptosis. assertion.
- assertion asSentence GPR30+is+necessary+for+estradiol-induced+changes+in+the+5-HT%281A%29+receptor+signaling+pathway+and+desensitization+of+5-HT%281A%29+receptor+signaling. assertion.
- assertion asSentence PDE5+controls+the+soluble+cyclic+GMP+pool+in+cardiac+myocytes. assertion.
- assertion asSentence UGGT+recognizes+the+hydrophobic+region+of+client+glycoproteins. assertion.
- assertion asSentence Cbl-b+promotes+chemotherapy-induced+apoptosis+in+rat+basophilic+leukemia+cells+through+inhibition+of+Akt+and+activation+of+ERK. assertion.
- assertion asSentence Polymerase+chain+reaction+used+to+check+the+expression+of+all+TRPM+and+TRPV+channel+members+with+specific+primers. assertion.
- assertion asSentence Endogenous+Ca%282%2B%29+buffer+proteins+play+a+critical+role+in+maintaining+TRPM4+channel+activity+in+native+cerebral+artery+smooth+muscle+cells. assertion.
- assertion asSentence GLYT2+is+associated+with+membrane+rafts+in+the+plasma+membrane+of+brainstem+terminals+and+neurons+and+is+functionally+modulated+by+the+lipid+environment. assertion.
- assertion asSentence There+is+a+tight+spatial+and+temporal+association+between+pre-inflammatory+changes+or+inflammation+and+PAP-expression. assertion.
- assertion asSentence Large+number+of+GAT2-immunoreactive+structures+that+surrounded+neurons+within+each+ganglion+of+the+myenteric+plexus. assertion.
- assertion asSentence Cathepsin+D+plays+an+important+role+in+the+phagocytosis+and+lysosomal+activation+of+macrophages%2Fmicroglia+during+the+central+nervous+system+inflammation+caused+by+trauma. assertion.
- assertion asSentence Rat+NL3+is+a+synaptic+adhesion+molecule+that+is+a+shared+component+of+glutamatergic+and+GABAergic+synapses. assertion.
- assertion asSentence Mechanisms+of+FOXC2-+and+FOXD1-mediated+regulation+of+the+RI+alpha+subunit+of+cAMP-dependent+protein+kinase+include+release+of+transcriptional+repression+and+activation+by+protein+kinase+B+alpha+and+cAMP. assertion.
- assertion asSentence Measured+mass+of+the+homotrimer+is+53+kDa%2C+allowing+for+the+mass+of+three+MGST+molecules+in+complex+with+one+glutathione+molecule. assertion.
- assertion asSentence Liver+cell+proliferation+requires+methionine+adenosyltransferase+2A+mRNA+up-regulation. assertion.
- assertion asSentence 1%2C25-dihydroxyvitamin+D2+specifically+induces+CYP3A9+in+rat+intestine+more+strongly+than+1%2C25-dihydroxyvitamin+D3+in+vivo+and+in+vitro. assertion.
- assertion asSentence mRNAs+and+proteins+for+inducible+nitric+oxide+synthase+and+tumor+necrosis+factor-alpha+are+more+easily+induced+in+CD40-expressing+microglia+than+CD40-negative+microglia%2C+after+lipopolysaccharide+stimulation. assertion.
- assertion asSentence In+the+cellular+micro-environment%2C+brain-type+creatine+kinase+activates+the+KCC2+function. assertion.
- assertion asSentence TRPM8+is+preferentially+expressed+within+a+subset+of+rapidly+responsive%2C+low-threshold+%28approximately+30+degrees+C%29%2C+cold-sensitive+neurons+in+trigeminal+ganglia. assertion.
- assertion asSentence A+chimera+in+which+the+proximal+part+of+the+C-terminal+of+Trpv1+replaces+an+equivalent+section+of+Trpm8+C-terminal+is+activated+by+PIP2+and+confers+the+phenotype+of+heat+activation. assertion.
- assertion asSentence Per1+gene+product+in+the+rat+suprachiasmatic+nucleus+is+modulated+by+seasonal+changes+in+daylength. assertion.
- assertion asSentence Calcium+calmodulin+kinase+1+alpha+regulates+the+functions+of+ribosomal+protein+S19+through+phosphorylation+of+Ser59. assertion.
- assertion asSentence Cys179+is+an+essential+site+for+inactivation+of+CaMKI+by+oxidants. assertion.
- assertion asSentence lgl1+plays+an+important+role+in+fetal+airway+branching+morphogenesis. assertion.
- assertion asSentence Can+associate+with+mitochondria. assertion.
- assertion asSentence 3%27G-oligodeoxyribonucleotides+enhance+nucleus+YB-1+to+inhibit+F-spondin+leading+to+cell+death+and+neurite+retraction+of+embryonic+neuron+cells. assertion.
- assertion asSentence Visceral+adipose+tissue-derived+serpin+%28vaspin%29+exerts+an+insulin-sensitizing+effect+targeted+toward+white+adipose+tissues+in+states+of+obesity. assertion.
- assertion asSentence Vaspin+inhibits+TNF-alpha-induced+expression+of+ICAM-1+via+preventing+the+reactive+oxygen+species+generation+and+subsequent+activation+of+NF-kappaB+and+PKCtheta%3B. assertion.
- assertion asSentence The+NMDAR3A+subunits+exhibit+developmental+loss+around+the+time+of+eye+opening+in+rat+suprachiasmatic+nucleus. assertion.
- assertion asSentence Intracerebroventricular+administration+of+PK2+affects+regulation+of+food+intake. assertion.
- assertion asSentence RimO%28rcn%29+catalyzes+the+attachment+of+a+methylthio+group+to+a+peptide+substrate+analogue+that+mimics+the+loop+structure+bearing+aspartyl+88+of+the+S12+ribosomal+protein+from+E.+coli. assertion.
- assertion asSentence A+common+function+of+IHF+and+HU+in+bacterial+cells+is+to+facilitate+DNA+organization+in+the+nucleoid+by+the+introduction+of+sharp+bends+in+chromosomal+DNA. assertion.
- assertion asSentence Ribosomes+change+into+forms+which+are+hard+to+bind+with+IF3+and+easy+to+form+100S+ribosomes+by+RMF+and+HPF+concomitantly+with+transition+from+the+log+phase+to+the+stationary+phase. assertion.
- assertion asSentence Hydrogen-dependent+reduction+of+benzyl+viologen+in+hydrogenases+HyaB%2C+HybC+and+HybE+is+dependent+on+the+%5BFe-S%5D-cluster-containing+small+subunit. assertion.
- assertion asSentence Lipoprotein+SmpA+is+a+component+of+the+YaeT+complex+that+assembles+outer+membrane+proteins+in+Escherichia+coli. assertion.
- assertion asSentence TorD+binds+tightly+and+with+exquisite+specificity+to+the+TorA+twin-arginine+signal+peptide+in+protein-targeting+pathways. assertion.
- assertion asSentence RraA+and+RraB+have+a+conserved+property+to+directly+act+on+RNAse+E-related+enzymes+and+inhibit+their+ribonucleolytic+activity. assertion.
- assertion asSentence Polymerization+of+MinE+over+MinD+oligomers+triggers+dynamic+instability+leading+to+detachment+from+the+membrane. assertion.
- assertion asSentence The+binding+sites+for+MinC+and+MinE+overlap+and+reveals+that+they+are+at+the+MinD+dimer+interface. assertion.
- assertion asSentence Polymerization+of+MinE+over+MinD+oligomers+triggers+dynamic+instability+leading+to+detachment+from+the+membrane. assertion.
- assertion asSentence ATP-binding+cassette+transporter+BtuCD+mediating+vitamin+B%2812%29+uptake+in+Escherichia+coli+couples+the+energy+of+ATP+hydrolysis+to+the+translocation+of+vitamin+B%2812%29+across+the+membrane+into+the+cell. assertion.
- assertion asSentence ClpA+utilizes+two+structural+elements%2C+one+in+the+N-temrinal+domain+and+the+other+in+the+pore+of+the+hexamer%2C+both+of+which+are+required+for+efficient+unfolding+of+some+protein+substrates. assertion.
- assertion asSentence NarJ+associated+with+a+peptide+of+the+first+50+residues+of+nitrate+reductase+catalytic+subunit+NarG. assertion.
- assertion asSentence Cpx+system+is+activated+also+in+a+pgsA+mutant. assertion.
- assertion asSentence NarL+and+NarP+carboxyl-terminal+domains+activate+transcription+from+Nar+class+II+control+regions. assertion.
- assertion asSentence The+protein+encoded+by+yggJ%2C+a+member+of+the+uncharacterized+DUF558+protein+family+of+predicted+alpha%2Fbeta+%28trefoil%29+knot+methyltransferases+is+responsible+for+methylation+at+U1498+in+16S+rRNA. assertion.
- assertion asSentence The+ygeW+encoded+protein+from+Escherichia+coli+is+a+knotted+ancestral+catabolic+transcarbamylase. assertion.
- assertion asSentence LeuO+and+H-NS+regulate+the+expression+of+the+yjjQ-bglJ+operon+and+yjjP. assertion.
- assertion asSentence It+binds+to+a+middle+domain+of+FliG+that+bridges+the+core+parts+of+the+rotor+and+parts+nearer+the+edge+that+interact+with+the+stator. assertion.
- assertion asSentence RcsB-BglJ+activates+one+of+two+H-NS-StpA+repressed+leuO+promoters. assertion.
- assertion asSentence The+attractive+force+that+governs+the+Cnu-H-NS+interaction+is+an+ionic+bond%2C+unlike+the+hydrophobic+interaction+that+is+the+major+attractive+force+in+most+proteins. assertion.
- assertion asSentence The+product+of+bacreriophage+T7+gene+5.5+%28gp5.5%29+forms+a+stable+complex+with+the+Escherichia+coli+histone-like+protein+H-NS+and+transfer+RNAs+%28tRNAs%29. assertion.
- assertion asSentence yddV+positively+controls+pgaABCD+expression+and+poly-N-acetylglucosamine+production. assertion.
- assertion asSentence E.+coli+FucU+forms+a+decameric+toroid+with+each+active+site+formed+by+two+adjacent+subunits. assertion.
- assertion asSentence After+input+of+protonmotive+force+mediated+through+ExbB%2FD+and+the+TonB+transmembrane+domain%2C+the+TonB+carboxy-terminus+can+form+a+meta-stable+high-energy+conformation+that+is+not+represented+by+the+crystal+structure+of+the+carboxy-terminus. assertion.
- assertion asSentence Proton-motive+force+is+required+for+the+interaction+of+ExbD+and+TonB+periplasmic+domains+trapped+by+formaldehyde+cross-linking. assertion.
- assertion asSentence ExbD-TonB+interactions+required+ExbD+transmembrane+domain+residue+D25. assertion.
- assertion asSentence Phosphorylation+site+not+required+for+regulation+of+RpoS+proteolysis. assertion.
- assertion asSentence Catalytic+roles+of+the+conserved+lysine+and+serine+found+at+the+active+site+of+DNA+topoisomerase+I. assertion.
- assertion asSentence The+Asp-to-Asn+substitutions+at+the+TOPRIM+domain+residues+can+selectively+decrease+Mg%282%2B%29+binding+affinity+with+minimal+disruption+of+the+active-site+geometry%2C+leading+to+trapping+of+the+covalent+complex+with+cleaved+DNA+and+causing+bacterial+cell+death. assertion.
- assertion asSentence NorM+protects+the+cell+from+reactive+oxygen+specie+when+the+8-oxoguanine-repair-deficient+mutant+cannot+cope+with+the+DNA+damage. assertion.
- assertion asSentence FtsB+is+associated+in+a+hierarchical+set+of+protein+complexes+and+its+assembly+can+occur+independently+of+%27upstream%27+proteins. assertion.
- assertion asSentence FlhE+acts+as+a+plug+or+a+chaperone+to+regulate+proton+flow+through+the+flagellar+yype+III+secretion+system. assertion.
- assertion asSentence The+attractive+force+that+governs+the+Cnu-H-NS+interaction+is+an+ionic+bond%2C+unlike+the+hydrophobic+interaction+that+is+the+major+attractive+force+in+most+proteins. assertion.
- assertion asSentence The+free+form+of+Lpp+is+an+integral+outer+membrane+protein+whose+C-terminus+is+exposed+on+the+cell+surface. assertion.
- assertion asSentence The+aryl+carrier+protein+%28ArCP%29+domain+of+EntB+interacts+specifically+with+EntH+to+help+with+the+proofreading+role+for+EntH+during+biosynthesis+of+enterobactin. assertion.