Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence DsbB+is+converted+by+its+specific+substrate%2C+DsbA%2C+to+a+superoxidizing+enzyme%2C+capable+of+oxidizing+this+extremely+oxidizing+oxidase. assertion.
- assertion asSentence ExbD-TonB+interactions+required+ExbD+transmembrane+domain+residue+D25. assertion.
- assertion asSentence Role+in+converting+the+initial+single-strand+DNA-protein+cleavage+complex+into+a+double-strand+break+prior+to+repair+by+homologous+recombination. assertion.
- assertion asSentence Tap+is+required+for+pyrimidine+chemotaxis. assertion.
- assertion asSentence F214A+substitution+in+P2+of+CheA+caused+1%2C000-fold+reduction+in+CheA-CheY+binding+affinity. assertion.
- assertion asSentence Enzyme+activation+in+the+ternary+complex+is+primarily+due+to+an+enhancement+of+ms+motions+that+allows+formation+of+a+population+of+enzymatically+active+conformers. assertion.
- assertion asSentence YefM+is+the+primary+transcriptional+repressor+of+the+yefM-yoeB+cassette. assertion.
- assertion asSentence CcmH+forms+a+tightly+interlinked+dimer+by+swapping+its+N-terminal+helix+between+two+monomers. assertion.
- assertion asSentence The+synergic+effect+of+two+specific+point+mutations+in+YeiK+increase+the+catalytic+efficiency+toward+purine+nucleosides+to+values+comparable+to+those+of+natural+nonspecific+nucleoside+hydrolases. assertion.
- assertion asSentence An+minimal+peptide+chain+length+of+6+amino+acids+and+an+N-terminal+formyl-methionyl-arginyl+sequence+of+microcin+C+are+required+for+YejABEF-mediated+uptake. assertion.
- assertion asSentence An+minimal+peptide+chain+length+of+6+amino+acids+and+an+N-terminal+formyl-methionyl-arginyl+sequence+of+microcin+C+are+required+for+YejABEF-mediated+uptake. assertion.
- assertion asSentence Expression+of+CcmB+facilitates+formation+of+the+CcmA2B1C1+complex+and+ATP-dependent+release+of+holoCcmE. assertion.
- assertion asSentence In+the+absence+of+ATP+hydrolysis+by+mutant+CcmA%2C+heme+chaperone+CcmE+is+incompetent+for+heme+transfer+to+an+apocytochrome+c+or+for+release+into+the+periplasm+as+a+soluble+variant. assertion.
- assertion asSentence Expression+of+CcmA+facilitates+formation+of+the+CcmA2B1C1+complex+and+ATP-dependent+release+of+holoCcmE. assertion.
- assertion asSentence The+key+reaction+in+UFA+synthesis+catalyzed+by+FabB+is+elongation+of+the+cis-3-decenoyl-ACP+produced+by+FabA. assertion.
- assertion asSentence BisC+has+an+essential+role+in+assimilation+of+oxidized+methionines. assertion.
- assertion asSentence The+periplasmic+phosphoquinolipoprotein+kinase+YfgL+plays+an+important+role+in+radiation-induced+DNA+strand+break+repair+and+homologous+recombination+in+E.+coli. assertion.
- assertion asSentence RodZ+is+not+absolutely+required+for+the+elongation+of+the+lateral+cell+wall+and+the+synthesis+of+functional+flagella. assertion.
- assertion asSentence The+iron-sulfur+cluster+assembly+in+E.+coli+IscU+is+an+IscS+mediated+biosynthetic+process. assertion.
- assertion asSentence The+desulfurase+activity+of+IscS+is+gradually+inhibited+as+the+amount+of+iron+and+sulfide+bound+to+IscS+increases. assertion.
- assertion asSentence All+three+recombination+mediator+proteins+RecFOR+are+needed+to+build+a+functionally+competent+RecA+filament+that+supports+efficient+Pol+V-mediated+translesion+synthesis+in+the+presence+of+ssDNA-binding+protein. assertion.
- assertion asSentence Hfq+modulates+the+sigmaE-mediated+envelope+stress+response+and+the+sigma32-mediated+cytoplasmic+stress+response+in+Escherichia+coli. assertion.
- assertion asSentence Recognition+of+beta-strand+motifs+of+sigma%28E%29+by+RseB+is+required+for+sigma%28E%29+activity. assertion.
- assertion asSentence LepA+protein%2C+present+in+all+bacteria+and+mitochondria%2C+is+a+third+elongation+factor+required+for+accurate+and+efficient+protein+synthesis. assertion.
- assertion asSentence YfiO+is+important+in+maintaining+the+functional+integrity+of+the+YaeT+complex+and+plays+a+critical+role+in+YaeT-mediated+outer+membrane+protein+folding. assertion.
- assertion asSentence Expression+of+E.+coli+K12+ygjG+coding+region+revealed+sigma54-depended+ORF+which+encodes+a+459-amino+acid+protein+with+putrescine%3A2-OG+aminotransferase+activity. assertion.
- assertion asSentence Functional+long-range+proton-coupled+electron+transfer+in+ribonucleoside+diphosphate+reductase+occurs+via+an+optimized+pathway+of+amino+acids+spanning+%3E35+A+across+the+alpha%3Abeta+interface. assertion.
- assertion asSentence The+combination+of+RecX+and+UvrD+are+required+for+suppression+of+constitutive+SOS+expression+by+RecA. assertion.
- assertion asSentence Uropathogenic+Escherichia+coli+strains+defective+in+regulation+of+the+SOS+response+mediated+by+RecA+and+LexA+display+attenuated+virulence+in+immunocompetent+mice+within+the+first+6+h+post+infection. assertion.
- assertion asSentence ATP+binding+to+full+length+enzyme+%28ARS875%29+and+to+an+N-terminal+construct+%28ARS461%29+is+endothermic+%28DeltaH+%3D+3-4+kcal+mol%28-1%29%29+with+stoichiometries+of+1%3A1+for+ARS461+and+2%3A1+for+full-length+dimer. assertion.
- assertion asSentence CsrA+and+DksA+are+both+necessary+for+full+expression+of+csrB+and+csrC. assertion.
- assertion asSentence RpoS+proteolysis+is+regulated+upon+carbon+starvation+by+a+mechanism+that+does+not+require+the+SprE+%28RssB%29+response+regulator+phosphorylation+site. assertion.
- assertion asSentence K%28%2B%29+is+responsible+for+influencing+the+binding+of+sigma%2870%29+and+sigma%28S%29+to+core+RNA+polymerase. assertion.
- assertion asSentence A+complex+of+CasABCDE+%28%27Cascade%27%29+also+promotes+formation+of+R-loops%2C+hybrids+of+RNA+base-paired+into+duplex+DNA. assertion.
- assertion asSentence The+interaction+between+%28p%29ppGpp+synthases+and+acyl+carrier+protein+restricted+to+bacteria+containing+the+RelA+and+SpoT+proteins. assertion.
- assertion asSentence The+mazE+and+mazF-mediated+cell+death+pathway+prevents+the+effect+of+DNA+damage+on+membrane+depolarization+in+E.+coli. assertion.
- assertion asSentence The+mazE+and+mazF-mediated+cell+death+pathway+prevents+the+effect+of+DNA+damage+on+membrane+depolarization+in+E.+coli. assertion.
- assertion asSentence RecBCD+enzyme+overproduction+impairs+DNA+repair+and+homologous+recombination+in+Escherichia+coli. assertion.
- assertion asSentence Two+variants+of+Escherichia+coli+5%27-nucleotidase+with+disulfide+bridges+that+are+engineered+to+link+the+two+domains+of+the+protein+are+used+to+demonstrate+that+a+large+domain+rotation+is+required+for+the+catalytic+mechanism+of+the+enzyme. assertion.
- assertion asSentence Mutation+of+the+conserved+active+site+residues+His243+and+His361+revealed+that+both+are+required+for+catalysis. assertion.
- assertion asSentence 6S+RNA+regulates+transcription+of+relA+encodes+a+ppGpp+synthase. assertion.
- assertion asSentence Transketolase+A+interacts+with+MarR+and+interfered+MarR+repression+of+the+marRAB+operon. assertion.
- assertion asSentence galP+is+repressed+by+a+combination+of+NagC%2C+GalR+and+GalS. assertion.
- assertion asSentence The+RcsB+and+RcsF+two-component+system+regulates+expression+of+lysozyme+inhibitors%2C+Ivy+and+MliC. assertion.
- assertion asSentence The+hypersensitivities+of+GspSA+and+GspSA%2Fglutaredoxin+null+mutants+to+H%282%29O%282%29+support+the+idea+that+GspSA+and+glutaredoxin+act+synergistically+to+regulate+the+redox+environment+of+E.+coli. assertion.
- assertion asSentence TolC+and+VceC+are+interchangeable+for+the+functioning+of+the+AcrAB+and+VceAB+pumps. assertion.
- assertion asSentence The+epimerase+reaction+follows+a+nonstereospecific+retroaldol%2Faldol+mechanism+with+the+same+reaction+intermediate+as+that+of+the+aldolase+reaction%2C+forming+the+basis+for+elucidating+the+catalytic+mechanism. assertion.
- assertion asSentence RelE+occupies+the+A+site+and+causes+cleavage+of+mRNA+after+the+second+nucleotide+of+the+codon+by+reorienting+and+activating+the+mRNA+for+2%27-OH-induced+hydrolysis. assertion.
- assertion asSentence Mug+glycosylase+is+engaged+in+the+repair+of+Etheno-DNA+adducts. assertion.
- assertion asSentence The+strength+of+the+-15+element+in+sigma%2870%29+promoter+inversely+correlates+with+the+strengths+of+the+-35+element+and+-10+element. assertion.
- assertion asSentence In+a+DnaJ+mutant+both+CbpA+and+DjlA+are+required+for+efficient+DnaK+mediated+protein+dissaggregation+at+42+degrees+C. assertion.
- assertion asSentence The+effects+of+different+metal+ions+on+catalysis+by+M1+RNA. assertion.
- assertion asSentence Periplasmic+amidases+AmiC+and+AmiA%2C+secreted+by+the+twin+arginine+transport+%28Tat%29+pathway%2C+are+localized+to+the+cytoplasm+in+Escherichia+coli+YqjA+and+YghB+double+mutant+cells. assertion.
- assertion asSentence YhbO+affects+a+central+process+in+stress+management. assertion.
- assertion asSentence The+constricted+central+channel+and+the+basic-charged+residues+in+the+channel+necks+of+PNPase+play+crucial+roles+in+trapping+RNA+for+processive+exonucleolytic+degradation. assertion.
- assertion asSentence Translational+control+by+PNPase+does+not+play+a+role+in+autoregulation+of+PNP+RNA. assertion.
- assertion asSentence Absence+of+PNPase+decreases+the+survival+of+cells+exposed+to+UV+radiation. assertion.
- assertion asSentence Strains+carrying+either+a+nusA+mutation+or+a+nusB+mutation+have+defects+in+transcription+of+23S+rRNA. assertion.
- assertion asSentence NusA%2C+a+modulator+of+RNA+polymerase%2C+interacts+with+the+DNA+polymerase+DinB. assertion.
- assertion asSentence The+C-terminus+of+LpxC+contains+a+signal+sequence+necessary+for+FtsH-dependent+degradation. assertion.
- assertion asSentence FtsH-dependent+processing+of+RNase+colicins+D+and+E3+means+that+only+the+cytotoxic+domains+are+imported+into+the+cytoplasm. assertion.
- assertion asSentence ObgE+is+required+to+license+chromosome+segregation+and+subsequent+cell+cycle+events. assertion.
- assertion asSentence GreA+mutations+increase+the+efficiency+of+RecA-mediated+recombination. assertion.
- assertion asSentence Recognition+of+ribosomal+protein+L11+by+the+protein+trimethyltransferase+PrmA. assertion.
- assertion asSentence The+transcription+of+the+cyaR+gene+is+stringently+controlled+by+cAMP-cAMP+receptor+protein+and%2C+unexpectedly%2C+cyaR+expression+is+also+up-regulated%2C+directly+or+indirectly%2C+by+sigma%28E%29. assertion.
- assertion asSentence The+conserved+arginine+357+of+SecY+is+essential+for+the+initiation+of+SecA-dependent+translocation+only. assertion.
- assertion asSentence Nascent+polypeptide-associated+complex+employs+a+conserved+ribosome+binding+domain+to+position+itself+on+the+L23+ribosomal+protein+adjacent+to+the+nascent+polypeptide+exit+site. assertion.
- assertion asSentence EF-Tu+in+Qbeta+replicase+modulates+RNA+elongation+processes+in+a+distinct+manner+from+its+established+function+in+protein+synthesis. assertion.
- assertion asSentence The+combined+introduction+of+loop+L2+and+PDZ+domain+1+of+DegP+into+DegS+converted+DegS+even+further+into+a+DegP-like+protease. assertion.
- assertion asSentence The+transcription+of+the+cyaR+gene+is+stringently+controlled+by+cAMP-cAMP+receptor+protein+and%2C+unexpectedly%2C+cyaR+expression+is+also+up-regulated%2C+directly+or+indirectly%2C+by+sigma%28E%29. assertion.
- assertion asSentence murQ+transcription+depends+on+the+activation+by+cyclic+AMP+%28cAMP%29-catabolite+activator+protein+%28CAP%29+bound+to+a+class+I+site+upstream+of+the+murQ+promoter. assertion.
- assertion asSentence FtsY+directly+interacts+with+the+SecY+translocon. assertion.
- assertion asSentence Membrane+binding+and+function+of+FtsY+are+in+part+regulated+by+proteolytic+cleavage+of+the+conserved+14-amino-acid+motif. assertion.
- assertion asSentence The+SRP+and+SR+GTPases%2C+without+recruiting+external+regulatory+factors%2C+constitute+a+self-sufficient+system+that+provides+exquisite+spatial+and+temporal+control+of+a+complex+cellular+process. assertion.
- assertion asSentence The+uspA+gene+is+also+regulated+by+an+intermediate+of+the+glycolytic%2Fgluconeogenic+pathways. assertion.
- assertion asSentence GadX%2FGadW-dependent+activation+of+the+acid+fitness+island+is+controlled+at+the+gadX-gadW+intergenic+region%2C+in+which+the+gadY+gene+is+located+and+transcribed+divergently+from+gadW. assertion.
- assertion asSentence GadX+increases+multidrug+resistance+in+E.+coli+through+activation+of+the+MdtEF+efflux+pump. assertion.
- assertion asSentence Loss+of+YibK+methylation+reduces+the+efficiency+of+codon-wobble+base+interaction%2C+as+demonstrated+in+an+amber+suppressor+supP+system. assertion.
- assertion asSentence SecB+exhibits+the+remarkable+ability+to+bind+a+diverse+group+of+ligands+recognizing+them+by+virtue+of+the+fact+that+they+have+non-native+structure. assertion.
- assertion asSentence The+interaction+between+%28p%29ppGpp+synthases+and+acyl+carrier+protein+restricted+to+bacteria+containing+the+RelA+and+SpoT+proteins. assertion.
- assertion asSentence YicJI+operon+is+necessary+for+its+fitness+under+all+the+growth+conditions. assertion.
- assertion asSentence All+three+recombination+mediator+proteins+RecFOR+are+needed+to+build+a+functionally+competent+RecA+filament+that+supports+efficient+Pol+V-mediated+translesion+synthesis+in+the+presence+of+ssDNA-binding+protein. assertion.
- assertion asSentence The+79-135+and+21-27+residues+of+Domain+II+of+E.+coli+DnaA+are+required+cell+viability. assertion.
- assertion asSentence Replication+initiation+in+DnaA-box+R4+mutants+is+insensitive+to+increased+levels+of+cellular+DnaA-ATP. assertion.
- assertion asSentence Hydrolysis+of+GTP+and+intact+complex+formation+in+the+MnmE-GidA+complex+is+essential+for+the+in+vitro+and+in+in+vivo+tRNA-modification+activity+which+employs+glycine+as+a+substrate. assertion.
- assertion asSentence Ammonia+channeling+in+bacterial+glucosamine-6-phosphate+synthase+%28Glms%29. assertion.
- assertion asSentence During+assembly+of+ATP+synthase%2C+alpha%2Fdelta+subunit+interaction+is+an+important+facet+of+proton+pumping+stator+subunit+structure+and+function. assertion.
- assertion asSentence ilvM+is+able+to+activate+the+large+subunits+of+all+three+acetolactate+synthase+I%2C+II+and+III+isozymes. assertion.
- assertion asSentence Tthe+in+vivo+Rho-dependent+termination+process+is+kinetically+controlled. assertion.
- assertion asSentence The+TatA+protein+represents+a+bifunctional+component+fulfilling+both+the+TatA+and+TatB+functions. assertion.
- assertion asSentence TatA+fused+to+green%2Fcyan%2Fyellow+fluorescent+protein+is+found+to+be+preferentially+incorporated+into+the+TatABC+complex. assertion.
- assertion asSentence UvrD+helicase+is+essential+for+Tus+removal+during+recombination-dependent+replication+restart+from+Ter+sites. assertion.
- assertion asSentence The+combination+of+RecX+and+UvrD+are+required+for+suppression+of+constitutive+SOS+expression+by+RecA. assertion.
- assertion asSentence The+CpxA+and+CpxR+regulated+genes+that+played+role+in+envelope+protein+misfolding+and+biofilm+formation. assertion.
- assertion asSentence All+four+unique+heterotropic+interactions+between+phosphoenolpyruvate+and+fructose+6-phosphate+contributed+to+the+inhibition+of+pfkA. assertion.
- assertion asSentence The+phosphate+sensor+is+required+for+efficient+autoregulation+of+RNase+E+synthesis. assertion.
- assertion asSentence GlpF+exists+as+a+stably+folded+tetramer+in+detergent+solutions+of+neutral+dodecyl+maltoside+and+in+zwitterionic+lysomyristoylphosphatidylcholine. assertion.
- assertion asSentence The+tetrameric+alpha-helical+GlpF+unfolds+via+a+dimeric+folding+intermediate. assertion.
- assertion asSentence PriA-catalysed+unwinding+of+branched+DNA+substrates+is+stimulated+specifically+by+contact+with+the+single-strand+DNA+binding+protein+of+E.coli%2C+SSB. assertion.
- assertion asSentence Helix+24+and+helix+45+of+KsgA+play+important+roles+in+catalysis+of+16S+rRNA. assertion.