Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Nej1p+is+phosphorylated+in+response+to+DNA+damage+in+a+manner+that+relies+on+the+DNA+damage+checkpoint+kinases+Mec1p%2C+Rad53p+and+Dun1p. assertion.
- assertion asSentence Nej1+physically+interacts+with+Srs2. assertion.
- assertion asSentence The+eIF2%2FeIF5+complex+represents+a+cytoplasmic+reservoir+for+eIF2+that+antagonizes+eIF2B-promoted+guanine+nucleotide+exchange%2C+enabling+coordinated+regulation+of+translation+initiation. assertion.
- assertion asSentence Overexpression+of+STT4+suppresses+the+temperature-sensitive+growth+defect+of+ypp1+mutants. assertion.
- assertion asSentence The+finger+subdomain+of+Est2p+facilitates+the+action+of+Pif1p+at+telomeres. assertion.
- assertion asSentence BNI1+and+BNR1+contribute+to+Bud6p-dependent+microtubule-cortex+interactions+by+controlling+Bud6p+localisation. assertion.
- assertion asSentence Nup2p+and+the+Ran+guanylyl-nucleotide+exchange+factor%2C+Prp20p%2C+interact+at+specific+chromatin+regions+and+enable+the+NPC+to+play+an+active+role+in+chromatin+organization+by+facilitating+the+transition+of+chromatin+between+activity+states. assertion.
- assertion asSentence Pct1+interacts+with+Kap60+and+Kap95+with+this+tripartite+complex+transiting+the+nuclear+pore. assertion.
- assertion asSentence Mitochondria-associated+F-box+proteins+Mfb1+and+Mdm30+are+key+components+of+a+complex+machinery+that+regulates+mitochondrial+dynamics+throughout+yeast%27s+entire+life+cycle. assertion.
- assertion asSentence Description+of+the+role+of+ssq1%2Fssc2+in+maturation+of+yeast+frataxin+%28Yfh1p%29. assertion.
- assertion asSentence Sec61+post-translational+translocation+is+dependent+on+assembly+with+Sss1p+complexes. assertion.
- assertion asSentence The+chromosome+segregation+is+impaired+in+SMC6+mutant+because+the+resolution+of+rDNA+repeats+is+blocked+during+anaphase. assertion.
- assertion asSentence SFP1+is+involved+in+cell+size+modulation+in+respiro-fermentative+growth+conditions. assertion.
- assertion asSentence The+interaction+between+the+half-a-tetratricopeptide+repeat+%28HAT%29+domain+of+Utp6+and+a+specific+peptide+in+Utp21%2C+is+investigated. assertion.
- assertion asSentence Rpn13+protein+is+involved+in+the+efficient+recognition+of+26S+proteasome+for+the+proteolysis+of+ubiquitinated+Gcn4p. assertion.
- assertion asSentence Dif1+is+required+for+nuclear+import+of+the+R2+subunit+and+plays+an+essential+role+in+regulating+the+dynamic+RNR+subcellular+localization. assertion.
- assertion asSentence Cln3+contains+a+chaperone-regulatory+Ji+domain+that+counteracts+Ydj1%2C+a+J+chaperone+essential+for+ER+release+and+nuclear+accumulation+of+Cln3+in+late+G1. assertion.
- assertion asSentence Regulation+of+CLN3+expression+by+Ace2+and+Ash1+can+account+for+the+differential+regulation+of+Start+in+response+to+cell+size+in+mothers+and+daughters. assertion.
- assertion asSentence The+spatial+regulation+of+GAL1+and+CLN3+transcripts+is+what+allows+growth+to+be+maintained+during+fluctuations+of+glucose+availability. assertion.
- assertion asSentence Hph2p+neither+interacts+with+nor+is+dephosphorylated+by+calcineurin. assertion.
- assertion asSentence Drs2p+is+an+essential+endocytic+cargo+in+cells+compromised+for+Ub-dependent+endocytosis. assertion.
- assertion asSentence Phosphatidylinositol-4-phosphate+tightly+controls+Drs2p-catalyzed+lipid+transport+and+establish+the+functional+relevance+of+the+Drs2p.Cdc50p+complex. assertion.
- assertion asSentence Gas1%2Ap+is+a+substrate+for+the+Pmt1p-Pmt2p+complex+and+is+degraded+by+the+ER-associated+protein+degradation+pathway. assertion.
- assertion asSentence Khd1+and+Ccr4+modulate+a+signal+from+Rho1+in+the+cell+wall+by+regulating+the+expression+of+RhoGEF+and+RhoGAP. assertion.
- assertion asSentence Stimulates+prion+formation+and+polymer+growth+by+stabilizing+misfolded+proteins. assertion.
- assertion asSentence The+TFC6+promoter+is+directly+regulated+by+the+TF%28III%29C+complex%2C+a+demonstration+of+an+RNA+polymerase+II+promoter+being+directly+responsive+to+a+core+Pol+III+transcription+factor+complex. assertion.
- assertion asSentence The+affinity+of+the+subunit+Spp1+for+modified+histone+H3+substrates+is+much+higher+than+that+of+Swd1+and+Swd3. assertion.
- assertion asSentence Control+of+telomeric+recombination+by+RFA1. assertion.
- assertion asSentence Rad24-2+truncation+protein+affects+telomere+structure+or+recombination+in+a+manner+distinct+from+rad24-delta. assertion.
- assertion asSentence Nop6+is+a+non-essential+nucleolar+protein+predicted+to+function+in+the+ribosome+biogenesis+process. assertion.
- assertion asSentence The+S.+cerevisiae+Cwc2+protein+functions+prior+to+step+1+of+splicing. assertion.
- assertion asSentence Higher+than+normal+levels+of+Cdc9p+expression+can+yield+genetic+instability+by+disrupting+the+normal+interplay+of+PCNA+with+other+proteins+such+as+Fen1. assertion.
- assertion asSentence Recruitment+of+Saccharomyces+cerevisiae+Dnl4-Lif1+complex+to+a+double-strand+break+requires+interactions+with+Yku80+and+the+Xrs2+FHA+domain. assertion.
- assertion asSentence Caf20+and+Dhh1+control+filamentation+by+regulating+STE12+translation. assertion.
- assertion asSentence Rdi1p+functions+in+cell+cycle-specific+Cdc42p+membrane+detachment. assertion.
- assertion asSentence The+Hrd1p+ligase+complex+unites+substrate+selection+in+the+ER+lumen+and+polyubiquitination+in+the+cytoplasm+and+links+these+processes+to+the+release+of+ER+proteins+via+the+Cdc48p+complex. assertion.
- assertion asSentence Dfm1+forms+a+complex+with+the+AAA-ATPase+Cdc48+in+a+strain+lacking+the+Cdc48+membrane-recruiting+component+Ubx2. assertion.
- assertion asSentence The+semi-conserved+pocket+of+negative+charge+within+the+%27acidic+ridge%27+region+significantly+increase+the+YFH1+structural+flexibility. assertion.
- assertion asSentence Iwr1+directs+RNA+polymerase+II+nuclear+import. assertion.
- assertion asSentence The+sequential+co-folding%2Fassociation+reaction+of+an+oligomeric+system+with+P0-%28P1A-P2B%29+protein+complex+as+an+essential+element+in+the+acquisition+of+a+stable+quaternary+structure+of+the+ribosomal+stalk. assertion.
- assertion asSentence Thi3p+causes+a+conformational+change+in+Pdc2p+leading+to+full+transactivation+activity+under+favorable+conditions. assertion.
- assertion asSentence Farnesylation+of+Pex19+is+not+needed+for+its+function+in+peroxisome+biogenesis+in+S.+cerevisiae. assertion.
- assertion asSentence sit4-110+has+pronounced+actin+polarization+defects+under+both+absence+and+presence+of+dipyridyl+disulfide. assertion.
- assertion asSentence SIR2+affects+DNA+topology+by+increasing+negative+supercoiling. assertion.
- assertion asSentence Recognition+of+the+binding+partners+of+Sir2+is+a+key+function+of+non-conserved+sequences. assertion.
- assertion asSentence The+deacetylation+of+H4K16%28ac%29+by+Sir2+actively+promotes+the+high-affinity+binding+of+the+SIR+holocomplex. assertion.
- assertion asSentence Isonicotinamide+enhances+Sir2+protein-mediated+silencing+and+longevity+in+yeast+by+raising+intracellular+NAD%2B+concentration. assertion.
- assertion asSentence Mps1+promotes+re-orientation+of+kinetochore-spindle+pole+connections+and+eliminates+those+that+do+not+generate+tension+between+sister+kinetochores. assertion.
- assertion asSentence This+activation+of+FLR1+transcription+is+fully+dependent+on+Yap1p+and+is+reduced+%28by+50%25%29+in+the+absence+of+Rpn4p%2C+Yrr1p+or+Pdr3p. assertion.
- assertion asSentence Nbp2+serves+as+the+network+hub+and+brings+seven+kinases+in+close+contact+to+Ptc1. assertion.
- assertion asSentence Trx1+and+Trx2+are+essential+for+the+nuclear+accumulation+of+Msn2%2F4+and+Maf1. assertion.
- assertion asSentence A+reverse+two-hybrid+selection+for+GAL3+mutations+that+impair+the+Gal3-Gal80+interaction+yielded+12+single-amino-acid+substitutions+at+residues+that+are+predicted+to+be+surface+exposed+on+Gal3. assertion.
- assertion asSentence Gal3p+moves+from+the+cytoplasm+to+the+nucleus+and+interact+with+Gal80p+in+response+to+galactose+induction. assertion.
- assertion asSentence The+predominance+of+dihydroxyacetone+phosphate+%28DHAP%29+on+the+enzyme+supports+a+mechanism+in+which+the+initial+proton+abstraction+in+the+reaction+from+DHAP+to+D-glyceraldehyde+3-phosphate+is+significantly+slower+than+the+subsequent+chemical+steps. assertion.
- assertion asSentence Budding+yeast+Mcm4+is+phosphorylated+in+vivo+during+S+phase+in+a+manner+dependent+on+the+presence+of+five+CDK+phosphoacceptor+residues+within+the+N-terminal+domain+of+Mcm4. assertion.
- assertion asSentence Cdc7p-Dbf4p+prevents+inappropriate+exit+from+mitosis+by+inhibiting+Polo+kinase+and+functions+in+the+spindle+position+checkpoint. assertion.
- assertion asSentence The+CK2+phosphorylation+of+catalytic+domain+of+Cdc34+modulates+its+activity+at+the+G1+to+S+transition+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Dual+mechanisms+specify+Doa4-mediated+deubiquitination+at+multivesicular+bodies. assertion.
- assertion asSentence Additional+mutational+suppressors+of+toopoisomerase+ii+defects. assertion.
- assertion asSentence Ubc13+is+required+for+G%282%29+delay+and+does+not+contribute+to+protein+turnover. assertion.
- assertion asSentence Acm1+and+Bmh1%2FBmh2+constitute+a+specialized+inhibitor+of+anaphase-promoting+complex%2FCCdh1. assertion.
- assertion asSentence Arx1+acts+as+an+export+receptor+for+the+60S+subunit. assertion.
- assertion asSentence KSS1+is+activated+by+Ste5. assertion.
- assertion asSentence The+dual+requirement+for+both+Ste7+and+this+Ste5+domain+in+Fus3+activation+explains+why+Fus3+is+selectively+activated+by+the+mating+pathway+and+not+by+other+pathways+that+also+utilize+Ste7. assertion.
- assertion asSentence Ino2p+activator+is+required+for+histone+acetylation. assertion.
- assertion asSentence Factors+required+for+activation+of+yeast+phospholipid+biosynthetic+genes+depend+on+activator+protein+Ino2+which+binds+to+the+inositol%2Fcholine-responsive+element. assertion.
- assertion asSentence A+dual+E3+mechanism+for+Rub1+ligation+to+Cdc53. assertion.
- assertion asSentence SSY1%2C+a+tranporter-like+sensor%2C+allows+the+cell+to+respond+to+changes+in+nutrient+availability+through+detection+of+the+relative+concentrations+of+intra-+and+extracellular+ligand. assertion.
- assertion asSentence Differential+regulation+of+transcription+factors+Stp1+and+Stp2+in+the+Ssy1-Ptr3-Ssy5+amino+acid+sensing+pathway. assertion.
- assertion asSentence Nbp2p+SH3+domain+made+contacts+with+the+Ste20+peptide+core+RXXPXXP+motif+and+the+Bem1p+SH3b+domain+made+stronger+contacts+with+residues+flanking+the+core+motif. assertion.
- assertion asSentence Hsp104+plus+other+factor%28s%29+in+the+yeast+cytosol+are+required+for+severing+Sup35+prion+fiber. assertion.
- assertion asSentence The+expression+of+gene+SUP35+at+the+transcription+and%28or%29+translation+level+is+regulated+by+environmental+conditions. assertion.
- assertion asSentence Hmo1+has+a+role+in+coordinating+the+transcription+of+rRNA+and+RP+genes. assertion.
- assertion asSentence Scc2+is+required+for+activating+the+expression+of+REC8+and+Scc2+is+necessary+for+recruiting+meiotic+cohesin+to+the+chromosome+to+generate+sister-chromatid+cohesion. assertion.
- assertion asSentence Coq4p+plays+an+essential+role+in+organizing+a+Coq+enzyme+complex+required+for+Q+biosynthesis. assertion.
- assertion asSentence RAD9-dependent+gene+up-regulation+is+required+for+nucleotide+excision+repair+only+when+this+process+is+coupled+to+transcription. assertion.
- assertion asSentence Deletion+of+SGS1+and+the+nuclease+EXO1+reduces+resection+at+uncapped+telomeres+and+together+with+deletion+of+RAD9+permits+cell+survival+without+CDC13. assertion.
- assertion asSentence Adk1p+regulates+ATP+metabolism+on+pre-RC+proteins+to+promote+pre-RC+assembly+and+activation. assertion.
- assertion asSentence Sir3-Sir4+complexes+form+progressively+higher+order+assemblies+with+increasing+protein+concentration%2C+with+implications+for+the+mechanism+of+gene+silencing. assertion.
- assertion asSentence The+crystal+structure+of+Saccharomyces+cerevisiae+Cia1+to+1.7+A+resolution. assertion.
- assertion asSentence Midsporulation+elements+in+the+SPS18-SPS19+promoter+region+are+targeted+by+the+Sum1p+repressor+in+association+with+Hst1p+and+Rfm1p. assertion.
- assertion asSentence Pex3p+functions+as+an+anchor+for+inheritance+protein+Inp1p+at+the+peroxisomal+membrane%2C+independently+of+its+role+at+the+endoplasmic+reticulum+in+peroxisome+biogenesis. assertion.
- assertion asSentence Mutants+are+hydroxyurea-+and+methylmethane+sulfonate-sensitive+due+to+their+S-phase+entry+defect. assertion.
- assertion asSentence Additive+roles+of+Vps74-mediated+and+sphingolipid-dependent+sorting+of+Golgi+residents. assertion.
- assertion asSentence RPB4%2FRPB7+is+a+nucleo-cytoplasmic+shuttling+heterodimer+that+interacts+with+Pol+II+and+with+mRNAs+and+is+required+for+mRNA+decay+in+the+cytoplasm. assertion.
- assertion asSentence Trs120p+is+required+for+vesicle+traffic+from+the+early+endosome+to+the+late+Golgi. assertion.
- assertion asSentence RAD30+%28polymerase+eta%29+replicates+through+8-oxoG+without+any+barriers+introduced+by+the+presence+of+the+lesion. assertion.
- assertion asSentence Proper+levels+of+Npl3+protein+are+achieved+by+a+negative+feedback+loop+in+which+phosphorylated+Npl3+suppresses+efficient+recognition+of+the+productive+processing+signals+in+its+own+transcript. assertion.
- assertion asSentence Loss+of+DOT1+influences+a+Rad50-dependent+nuclease%2C+leading+to+more+rapid+accumulation+of+ssDNA. assertion.
- assertion asSentence Rmt2+has+nuclear+and+cytoplasmic+localizations+and+influences+the+transcription+of+MYO1%2C+required+for+cytokinesis. assertion.
- assertion asSentence PHO8+promoter+has+greater+nucleosome+positioning+power+and+the+properly+positioned+nucleosomes+are+more+stable+than+those+at+the+PHO5+promoter. assertion.
- assertion asSentence Purification+yields+an+essentially+homogeneous+enzyme+that+is+stable+for+several+years+upon+storage+at+-80+degrees. assertion.
- assertion asSentence The+Pkc1+protein+mediates+oxidative+signalling+by+helping+to+downregulate+ribosomal+gene+expression+when+cells+are+exposed+to+hydrogen+peroxide. assertion.
- assertion asSentence Tel1p+preferentially+associates+with+the+shortest+telomeres+and+stimulates+their+elongation+by+telomerase. assertion.
- assertion asSentence Autophagy-related+protein+8+%28Atg8%29+family+interacting+motif+in+Atg3+mediates+the+Atg3-Atg8+interaction+and+is+crucial+for+the+cytoplasm-to-vacuole+targeting+pathway. assertion.
- assertion asSentence Kti13+and+Kti11+support+Elongator+functions+and+they+both+share+Elongator-independent+roles+that+are+important+for+cell+viability. assertion.
- assertion asSentence Casein+kinase+Yck1p+phosphorylates+Khd1p+at+the+plasma+membrane%2C+disrupting+the+Khd1p-RNA+complex+and+releasing+its+translational+repression+on+the+ASH1+mRNA. assertion.
- assertion asSentence The+C-terminal+region+of+the+second+cytosolic+loop+in+AAC2+changes+its+environment+when+the+carrier+cycles+between+the+matrix+and+cytosolic+state. assertion.
- assertion asSentence Pleiotropic+effects+of+the+yeast+Sal1+and+Aac2+carriers+on+mitochondrial+function+via+an+activity+distinct+from+adenine+nucleotide+transport. assertion.
- assertion asSentence Fus3-triggered+Tec1+degradation+modulates+mating+transcriptional+output+during+the+pheromone+response. assertion.