Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence MSA1+is+a+high+copy+suppressor+of+a+drc1-1+mutant. assertion.
- assertion asSentence An+essential+nuclear+pore+complex+protein+in+Saccharomyces+cerevisiae%2C+important+for+Msn5-mediated+nuclear+protein+export. assertion.
- assertion asSentence Mtr4p+displays+a+marked+preference+for+binding+to+poly%28A%29+RNA+relative+to+an+oligoribonucleotide+of+the+same+length+and+a+random+sequence. assertion.
- assertion asSentence Crystal+structure+of+the+ADAT2-ADAT3+heterodimer. assertion.
- assertion asSentence In+vivo+Mad3+phosphorylation+depends+on+the+Polo+kinase+Cdc5+and%2C+to+a+minor+extent%2C+the+Aurora+B+kinase+Ipl1. assertion.
- assertion asSentence Ipl1p-dependent+phosphorylation+of+Mad3p+is+required+for+the+spindle+checkpoint+response+to+lack+of+tension+at+kinetochores. assertion.
- assertion asSentence Pol31+and+Pol32+subunits+of+yeast+DNA+polymerase+delta+are+also+essential+subunits+of+DNA+polymerase+zeta. assertion.
- assertion asSentence The+Ess1+peptidyl+prolyl+isomerase+functionally+interacts+with+the+transcription+initiation+factor+TFIIB+and+with+the+Ssu72+C-terminal+domain+phosphatase+and+Pta1+components+of+the+CPF+3%27-end+processing+complex. assertion.
- assertion asSentence Vps55p+and+Vps68p+form+a+complex+that+acts+with+or+downstream+of+ESCRT+function+to+regulate+endosomal+trafficking. assertion.
- assertion asSentence Cbf1+is+required+for+transcription+at+centromere+DNA. assertion.
- assertion asSentence TOR1+and+TOR2+have+distinct+localization+patterns%2C+consistent+with+the+regulation+of+cellular+processes. assertion.
- assertion asSentence Tor1+and+Sch9+are+central+components+of+a+network+that+controls+a+common+set+of+genes+implicated+in+a+metabolic+switch+from+the+TCA+cycle+and+respiration+to+glycolysis+and+glycerol+biosynthesis. assertion.
- assertion asSentence Npr2%2F3+complex+mediates+an+amino+acid+starvation+signal+to+TORC1. assertion.
- assertion asSentence Ent3p+is+a+connector+between+PtdIns%283%2C5%29P%282%29-+and+the+Vps27p-ubiquitin-driven+sorting+machinery+at+the+multivesicular+body. assertion.
- assertion asSentence TOR1+and+TOR2+have+distinct+localization+patterns%2C+consistent+with+the+regulation+of+cellular+processes. assertion.
- assertion asSentence Regulation+of+CLN3+expression+by+Ace2+and+Ash1+can+account+for+the+differential+regulation+of+Start+in+response+to+cell+size+in+mothers+and+daughters. assertion.
- assertion asSentence Fatty+acid+synthase+%28Fas%29+plays+a+key+role+during+the+cellular+response+of+Saccharomyces+cerevisiae+to+H2O2. assertion.
- assertion asSentence Mot1-mediated+activation+of+URA1+transcription+involves+at+least+two+steps%2C+one+of+which+is+the+removal+of+TBP+bound+to+the+promoter+in+the+opposite+orientation+required+for+URA1+transcription. assertion.
- assertion asSentence A+methylated+cysteine+residue+at+position+39+of+S.+cerevisiae+Rps27a+is+demonstrated+in+a+small+ribosomal+subunit+zinc-cysteine+cluster. assertion.
- assertion asSentence mRNA+localization+involves+association+of+She2p+and+mRNPs+with+endoplasmic+reticulum+tubules+and+myosin-dependent+cotransport+of+tubules+and+localized+mRNPs. assertion.
- assertion asSentence She2p+interacts+with+both+Loc1p+and+Puf6p+and+excluding+She2p+from+the+nucleus+decreases+this+interaction. assertion.
- assertion asSentence Protein+kinase+Ypk1+phosphorylates+regulatory+proteins+Orm1+and+Orm2+to+control+sphingolipid+homeostasis+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence The+effect+on+global+gene+expression+of+loss+of+binding+of+Abf1. assertion.
- assertion asSentence MSA1+is+a+high+copy+suppressor+of+a+drc1-1+mutant. assertion.
- assertion asSentence ESCRT-II+coordinates+the+assembly+of+ESCRT-III+filaments+for+cargo+sorting+and+multivesicular+body+vesicle+formation. assertion.
- assertion asSentence Ribosome+stalk+assembly+requires+the+dual-specificity+phosphatase+Yvh1+for+the+exchange+of+Mrt4+with+P0. assertion.
- assertion asSentence Vps1+and+Rvs167+function+together+to+mediate+scission+during+endocytosis+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence The+intermembrane+space+domains+of+mitofilin+play+distinct+roles+in+interactions+with+outer+membrane+complexes+and+maintenance+of+MINOS+and+cristae+morphology. assertion.
- assertion asSentence EKC%2FKEOPS+complex+is+specifically+involved+in+the+regulation+of+Bud9p+localization+downstream+of+Rax1p%2FRax2p. assertion.
- assertion asSentence Gat1+and+Gat2+localized+to+both+perinuclear+and+cortical+endoplasmic+reticula+in+actively+proliferating+cells. assertion.
- assertion asSentence The+DEAH+box+ATPases+Prp16+and+Prp43+cooperate+to+proofread+5%27+splice+site+cleavage+during+pre-mRNA+splicing. assertion.
- assertion asSentence GRE2+is+involved+in+ergosterol+metabolism+in+Saccharomyces+cerevisiae+and+significantly+effects+growth. assertion.
- assertion asSentence Some+mutations+located+in+the+conserved+motifs+and+at+the+interface+between+the+two+Dhh1+domains+confer+dominant+negative+phenotypes+in+vivo+and+disrupt+the+conformational+switch+in+vitro. assertion.
- assertion asSentence Unlike+Ndj1%2C+Csm4+is+not+required+for+meiosis-specific+telomere+association. assertion.
- assertion asSentence hMI1%2C+a+DNA+helicase%2C+is+involved+in+the+maintenance+of+mtDNA. assertion.
- assertion asSentence The+binding+of+MSH2-MSH3+to+mismatch+DNA+involves+protein-DNA+contacts+that+appear+very+different+from+those+required+for+MSH2-MSH6+mismatch+binding. assertion.
- assertion asSentence A+yeast+strain+with+an+extra+copy+of+the+ADH1+gene+%282xADH1%29+demonstrated+increased+survival+in+stationary+phase+and+a+30%25+extension+in+replicative+life+span. assertion.
- assertion asSentence Direct+Avo1-Ypk2+interaction+is+crucial+for+TORC2+signaling+to+the+downstream+Ypk2+pathway. assertion.
- assertion asSentence Sir2+and+Hst1+subfunctionalized+by+acquiring+complementary+inactivating+mutations+in+these+interaction+domains. assertion.
- assertion asSentence Degradation+of+several+hypomodified+mature+tRNA+species+in+Saccharomyces+cerevisiae+is+mediated+by+Met22+and+the+5%27-3%27+exonucleases+Rat1+and+Xrn1. assertion.
- assertion asSentence Smc5%2F6+complex+is+needed+during+replication+to+prevent+the+accumulation+of+branched+chromosome+structures. assertion.
- assertion asSentence Multiple+ubiquitin-specific+proteases+are+involved+in+hydrostatic+pressure-induced+degradation+of+Tat2%2C+rather+than+free+ubiquitin+depletion. assertion.
- assertion asSentence GPI-anchored+proteins+are+required+for+the+recruitment+of+membrane+proteins+Tat2p+and+Fur4p+to+the+plasma+membrane+via+detergent-resistant+membranes. assertion.
- assertion asSentence Rrp6+plays+a+role+in+degrading+distinct+classes+of+meiotically+induced+noncoding+RNAs+during+vegetative+growth+and+the+onset+of+meiosis. assertion.
- assertion asSentence Dnl4+mutation+suppressed+elevated+levels+of+chromosome+loss+and+telomere+fusion+associated+with+mono-allelic+expression+of+MAT. assertion.
- assertion asSentence WSC1+is+involved+in+reorganization+of+the+actin+cytoskeleton+in+response+to+hypo-osmotic+shock+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence The+dynamic+localization+of+Wsc1p%2C+a+sensor+of+the+extracellular+wall+in+yeast%2C+resembles+polarized+distribution+of+certain+extracellular+matrix-sensing+integrins+through+endocytic+recycling. assertion.
- assertion asSentence Aus1+and+Pdr11+are+required+for+sterol+uptake. assertion.
- assertion asSentence Exo1+processes+nucleotide+excision+repair+%28NER%29+intermediates+when+repair+synthesis+is+impeded%2C+converting+NER+intermediates+to+long+ssDNA+gaps+and+promoting+checkpoint+activation. assertion.
- assertion asSentence Sgt1+dimerization+is+required+for+kinetochore+assembly. assertion.
- assertion asSentence 3-methylhistidine+modification+of+Rpl3+is+dependent+upon+the+YIL110W+methyltransferase. assertion.
- assertion asSentence Ypt1p+regulates+the+flow+of+traffic+into+the+cis+and+trans+side+of+the+Golgi+via+multiple+effectors. assertion.
- assertion asSentence Bub1+kinase+and+Sgo1p+act+together+to+ensure+efficient+biorientation+of+sister+chromatids+during+mitosis. assertion.
- assertion asSentence Sgo1+acts+at+sister+kinetochores+to+promote+their+biorientation. assertion.
- assertion asSentence Sgo1+can+inhibit+separase+activity+independently+of+securin. assertion.
- assertion asSentence Cex1p+recruits+Rna1p+from+the+cytoplasm+to+the+nuclear+pore+complex+and+facilitates+Rna1p+activation+of+the+GTPase+activity+of+Gsp1p+by+enabling+Rna1p+to+gain+access+to+Gsp1p-GTP+bound+to+the+Los1p-tRNA-Gsp1p-GTP+export+complex. assertion.
- assertion asSentence Sfl1p+is+a+key+component+of+the+transcriptional+control+of+the+stress+responsive+gene+HSP30. assertion.
- assertion asSentence The+PIAS+homologue+Siz2+regulates+perinuclear+telomere+position+and+telomerase+activity+in+budding+yeast. assertion.
- assertion asSentence The+sumoylating+activity+of+Siz2+at+the+nuclear+periphery+acts+to+maintain+a+balance+of+sumoylation+that+supports+the+localization+of+Sir2%2FSir4+to+these+silent+regions. assertion.
- assertion asSentence Pology+of+1-acyl-sn-glycerol-3-phosphate+acyltransferases+SLC1+and+ALE1+and+related+membrane-bound+O-acyltransferases+%28MBOATs%29+of+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Syc1%2C+by+mimicking+the+essential+Brr5+C-terminus%2C+serves+as+a+negative+regulator+of+mRNA+3%27-end+formation. assertion.
- assertion asSentence The+Ies4+subunit+of+the+INO80+complex+is+a+functional+component+in+the+Mec1%2FTel1+DNA+damage+signaling+pathway+that+modulates+checkpoint+responses. assertion.
- assertion asSentence ScPex11p+promotes+the+proliferation+of+peroxisomes+already+present+in+the+cell%2C+ScPex25p+initiates+remodeling+at+the+peroxisomal+membrane+and+ScPex27p+acts+to+counter+this+activity. assertion.
- assertion asSentence Knockout+of+caspase-like+gene%2C+YCA1%2C+abrogates+apoptosis+and+elevates+oxidized+proteins+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Metacaspase+is+associated+with+mitochondrial+respiration%2C+intracellular+redox+control+and+genomic+stability. assertion.
- assertion asSentence Ded1+uses+the+single-stranded+region+to+gain+access+to+the+duplex%2C+strand+separation+is+directly+initiated+from+the+duplex+region+and+no+covalent+connection+between+the+single+strand+and+the+duplex+region+is+required. assertion.
- assertion asSentence Duplex+unwinding+by+Ded1%2FMss116+is+based+on+local+destabilization+of+RNA+helical+regions. assertion.
- assertion asSentence The+Hog+1+common+docking+%26+PBD-2+docking+sites+are+also+involved+in+the+specific+interaction+between+Hog1+%26+Ptp2+and+govern+the+dynamic+dephosphorylation+of+activated+Hog1. assertion.
- assertion asSentence WTM1+amplifies+transcriptional+induction+of+RNR3+in+response+to+replication+stress+and+modulates+expression+of+genes+encoding+other+RNR+subunits. assertion.
- assertion asSentence Dga1+deficiency+triggers+fatty+acid-mediated+cell+death. assertion.
- assertion asSentence Cdc31+bound+with+Sfi1+in+a+complex+have+a+role+in+spindle+pole+body+duplication. assertion.
- assertion asSentence Caf20+and+Dhh1+control+filamentation+by+regulating+STE12+translation. assertion.
- assertion asSentence Myo2p+is+subject+to+phosphoregulation+involving+a+PKA-related+signaling+pathway. assertion.
- assertion asSentence Inp2p+is+the+first+peroxisomal+protein+implicated+in+the+vectorial+movement+of+peroxisomes.Inp2p+interacts+directly+with+the+globular+tail+of+Myo2p. assertion.
- assertion asSentence Myosin+light+chain+1+%28Mlc1p%29%2C+required+for+vesicle+delivery+at+the+mother-bud+neck+during+cytokinesis%2C+binds+to+the+Myo2p+GTD+in+a+region+overlapping+that+of+Ypt32p. assertion.
- assertion asSentence Ypt11+and+Ret2+are+components+of+a+Myo2+receptor+complex+that+functions+during+the+Golgi+inheritance+into+the+growing+bud. assertion.
- assertion asSentence Ty1+activation+in+response+to+adenylic+nucleotide+depletion+requires+the+DNA-binding+transcription+factor+Tye7. assertion.
- assertion asSentence VTS1+is+a+multi-copy+suppressor+of+dna2-K1080E%2C+a+lethal+mutant+allele+of+DNA2+that+lacks+DNA+helicase+activity. assertion.
- assertion asSentence Presequence+either+targets+Atp6p+to+the+Atp9p+or+signals+insertion+of+the+Atp6p+precursor+into+a+microcompartment+of+the+membrane+for+more+efficient+interaction+with+the+Atp9p+ring. assertion.
- assertion asSentence Fully+assembled+ATPase+and+its+proton+pumping+function+are+both+required+for+COX+biogenesis+in+yeast+and+mammalian+cells+through+a+mechanism+independent+of+Cox1p+synthesis. assertion.
- assertion asSentence Specific+Cox1+proteolysis+in+coa2Delta+cells+arises+from+a+combination+of+Oma1+activation+and+a+susceptible+conformation+of+Cox1. assertion.
- assertion asSentence Two+subunits+6+are+close+in+the+inner+mitochondrial+membrane+and+in+the+solubilized+supramolecular+forms+of+the+yeast+ATP+synthase. assertion.
- assertion asSentence Gts1p+plays+a+major+role+in+the+oscillatory+expression+of+TPS1+and+SUC2+in+continuous+cultures+of+Saccharomyces+cerevisiae. assertion.
- assertion asSentence During+polarization%2C+cells+change+from+fast+to+slow+cable+dynamics+through+spatio-temporal+regulation+of+Bni1%2C+Bnr1+and+Myo2. assertion.
- assertion asSentence Mcm10+is+required+for+the+maintenance+of+transcriptional+silencing+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Modulation+of+yeast+Sln1+kinase+activity+by+the+CCW12+cell+wall+protein. assertion.
- assertion asSentence The+ability+of+Rho3+and+Cdc42+to+hydrolyze+GTP+is+not+required+for+their+role+in+secretion. assertion.
- assertion asSentence COX5a+is+switched+off+and+COX5b+is+switched+on+when+the+O2+concentration+drops+below+a+threshold+of+0.5+microM+O2. assertion.
- assertion asSentence Slm+proteins+are+required+for+proper+eisosome+organization%2C+endocytic+trafficking+and+recycling+in+the+yeast+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Overexpressed+Prk1+conferred+Adriamycin+resistance+in+yeast+cells. assertion.
- assertion asSentence Vid24p+and+Sec28p+are+present+at+actin+patches+during+glucose+starvation. assertion.
- assertion asSentence The+stability+of+these+DNA-binding+cofactors+is+regulated+by+SCF%28Met30%29. assertion.
- assertion asSentence The+N-terminal+domains+is+essential+for+Ulp2+function+and+is+required+for+nuclear+targeting. assertion.
- assertion asSentence C-terminal+region+of+Ulp2+is+phosphorylated+during+mitosis+in+a+Cdc5-dependent+manner. assertion.
- assertion asSentence Dimerization+of+Est3p+contributes+to+telomere+maintenance. assertion.
- assertion asSentence FLO11+has+a+role+in+biofilm+formation+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Global+signaling+pathways+respond+with+specific+sensitivity+to+regulate+the+expression+of+FLO11+under+nitrogen+limitation. assertion.
- assertion asSentence Yeast+zinc+cluster+proteins+Dal81+and+Uga3+cooperate+by+targeting+common+coactivators+for+transcriptional+activation+of+gamma-aminobutyrate+responsive+genes. assertion.
- assertion asSentence In+the+direction+of+lysine+formation%2C+once+NAD%2B+and+saccharopine+bind%2C+a+group+with+a+pKa+of+6.2+accepts+a+proton+from+the+secondary+amine+of+saccharopine+as+it+is+oxidized. assertion.
- assertion asSentence The+ability+of+Rad1-Rad10+nuclease+to+associate+in+a+complex+with+Rad14+is+paramount+for+the+targeting+of+this+nuclease+to+lesion+sites+in+vivo. assertion.