Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Phosphorylation+of+War1p%2C+its+activation+and+DNA+binding+are+tightly+linked+processes+that+are+essential+for+adaptation+to+weak-acid+stress. assertion.
- assertion asSentence The+intramolecular+electron+transfer+from+the+a+domain+to+the+a%27+domain+within+PDI+during+its+oxidation+by+ERO1alpha. assertion.
- assertion asSentence A+natural+coding-region+polymorphism+in+the+inorganic+phosphate+transporter+PHO84+underlies+sensitivity+to+two+polychlorinated+phenols+that+uncouple+oxidative+phosphorylation. assertion.
- assertion asSentence Vam6+controls+TORC1%28Tco89%29+function+by+activating+the+Gtr1+subunit+of+the+EGO+complex. assertion.
- assertion asSentence Crystal+structure+of+the+Gtr1p%28GTP%29-Gtr2p%28GDP%29+protein+complex+reveals+large+structural+rearrangements+triggered+by+GTP-to-GDP+conversion. assertion.
- assertion asSentence Cdc55p%2FZds2p+module+has+a+function+in+the+regulation+of+the+Swe1p-dependent+G2%2FM+checkpoint. assertion.
- assertion asSentence Has+a+direct+role+in+the+prevention+or+repair+of+Sgs1-induced+DNA+damage+that+accumulates+in+top3+mutants. assertion.
- assertion asSentence The+finger+subdomain+of+Est2p+facilitates+the+action+of+Pif1p+at+telomeres. assertion.
- assertion asSentence Pif1+directs+long+flaps+toward+the+two-nuclease+pathway%2C+requiring+Dna2+cleavage+for+primer+removal. assertion.
- assertion asSentence Rad52+within+the+complex+associates+with+double-stranded+DNA+to+assist+Rad51-mediated+homologous+pairing. assertion.
- assertion asSentence Ty1+sequence-specific+gross+chromosomal+rearrangements+are+RAD52-dependent. assertion.
- assertion asSentence Usa1p+is+required+for+optimal+function+and+regulation+of+the+Hrd1p+endoplasmic+reticulum-associated+degradation+ubiquitin+ligase. assertion.
- assertion asSentence Cdc28+activates+Cdc5+via+phosphorylation+of+threonine+242. assertion.
- assertion asSentence Cdc5+induces+the+asymmetric+distribution+of+Bfa1+to+the+bud-directed+spindle+pole+body+independently+of+Bfa1+GAP+activity+at+anaphase. assertion.
- assertion asSentence PP2A+and+the+Tor+kinase+pathway+transduce+stress+and+nitrogen+starvation+signals+to+Msn2p. assertion.
- assertion asSentence The+general+stress+responses+of+yeast+genes+are+activated+by+Msn2. assertion.
- assertion asSentence Stress+response+transcription+factors+Msn2p%2F4p+are+repressed+by+protein+kinase+A. assertion.
- assertion asSentence Crz1+destabilizes+Msn2%2FMsn4+in+the+nuclei+of+cells+in+response+to+Ca2%2B+signalling. assertion.
- assertion asSentence Mcm1p+contributes+to+active+transcription+at+the+ARG1+promoter+by+increasing+the+binding+of+the+activator+Gcn4p+and+by+recruiting+the+co-activator+complex+SWI%2FSNF+at+ARG1+under+Gcn4p-induced+conditions. assertion.
- assertion asSentence Mcm1p+binding+positively+regulate+ARG1+transcription+and+cell+growth+in+the+absence+of+arginine+and+Gcn4p. assertion.
- assertion asSentence Regulation+of+cytokinesis+and+septation+in+budding+yeast+by+Bub2. assertion.
- assertion asSentence Tvp+proteins+collectively+assist+in+the+effective+maintenance%2Ffunction+of+the+late+Golgi%2Fendosomal+compartments. assertion.
- assertion asSentence YMR099cp+adopts+the+same+fold+as+galactose+mutarotase+and+shares+the+same+catalytic+machinery+necessary+for+the+interconversion+of+the+alpha+and+beta+anomers+of+galactose. assertion.
- assertion asSentence Direct+Avo1-Ypk2+interaction+is+crucial+for+TORC2+signaling+to+the+downstream+Ypk2+pathway. assertion.
- assertion asSentence Myo5+facilitates+the+membrane+fusion%2Fvesicle+scission+event+of+endocytosis. assertion.
- assertion asSentence The+interaction+between+Fhl1p+and+Ifh1p+is+critical+for+the+regulation+of+CPC2+transcription+during+utilization+of+different+carbon+sources. assertion.
- assertion asSentence Deletion+of+CPC2%2FASC1+abolished+amino+acid+starvation-induced+adhesive+growth+and+impaired+basal+expression+of+FLO11+and+its+activation+upon+starvation+in+haploid+cells. assertion.
- assertion asSentence RACK1+functions+from+the+ribosome%2C+implying+a+physical+link+between+the+eukaryotic+ribosome+and+cell+signaling+pathways+in+vivo. assertion.
- assertion asSentence NUP53+is+a+target+of+CDK1+and+HRR25. assertion.
- assertion asSentence F154+plays+a+critical+role+in+the+assembly+of+a+functional+Atg12-Atg5.Atg16+complex+that+is+requisite+for+autophagosome+formation. assertion.
- assertion asSentence Dephosphorylation+of+Pah1p+by+the+Nem1p-Spo7p+complex+enables+the+amphipathic+helix+to+anchor+Pah1p+onto+the+nuclear%2FER+membrane+allowing+the+production+of+diacylglycerol+for+lipid+biosynthesis. assertion.
- assertion asSentence MRPS17+is+essential+for+mitochondrial+function. assertion.
- assertion asSentence In+the+absence+of+Srs2+or+Sgs1%2C+DNA+damage+accumulates+and+is+processed+by+homologous+recombination%2C+triggering+repeat+rearrangements. assertion.
- assertion asSentence Sgs1+plays+a+role+in+transcriptional+regulation+and+acts+as+a+repressor+of+a+subset+of+rapamycin+responsive+genes. assertion.
- assertion asSentence In+gyp5Deltagyl1Delta+cells%2C+Rvs167p+is+not+correctly+localized+to+the+small-bud+tip. assertion.
- assertion asSentence Cik1+targets+the+minus-end+kinesin+depolymerase+kar3+to+microtubule+plus+ends. assertion.
- assertion asSentence Overexpression+of+ERG6+and+ERG2+led+to+an+increased+ergosterol+level. assertion.
- assertion asSentence Mre11+mutations+are+associated+with+increased+rates+of+spontaneous+loss+of+heterozygosity+leading+to+genome+instability. assertion.
- assertion asSentence Mre11+mutation+promotes+telomere+recombination+and+an+efficient+bypass+of+senescence. assertion.
- assertion asSentence Cex1p+recruits+Rna1p+from+the+cytoplasm+to+the+nuclear+pore+complex+and+facilitates+Rna1p+activation+of+the+GTPase+activity+of+Gsp1p+by+enabling+Rna1p+to+gain+access+to+Gsp1p-GTP+bound+to+the+Los1p-tRNA-Gsp1p-GTP+export+complex. assertion.
- assertion asSentence Zrc1+and+Cot1+vacuolar+zinc+transporters+control+alkaline+phosphatase+accumulation+and+activity. assertion.
- assertion asSentence Overexpression+of+the+COX2+mRNA-specific+translational+activator+Pet111+inhibits+translation+of+COX1+mRNA+and+interferes+with+cytochrome+c+oxidase+assembly. assertion.
- assertion asSentence The+OB-fold+is+crucial+for+ribosome-binding+and+the+C-terminal+domain+of+eIF1A+has+eukaryotic-specific+functions+in+ternary+complex+recruitment+and+scanning. assertion.
- assertion asSentence Structure+of+the+RNA+recognition+motifs+of+splicing+factor+prp24. assertion.
- assertion asSentence Zds1p+associates+with+the+complex+formed+by+fungal+proteins+and+nucleoporins+at+the+cytosolic+fibrils+of+the+nuclear+pore+complex+and+is+required+for+optimal+mRNA+export. assertion.
- assertion asSentence Fcp1+directly+recognizes+the+C-terminal+domain+%28CTD%29+and+interacts+with+a+site+on+RNA+polymerase+II+distinct+from+the+CTD. assertion.
- assertion asSentence Ssu72+catalyzes+serine-5-P+dephosphorylation+subsequent+to+addition+of+the+7-methylguanosine+cap+on+pre-mRNA+in+a+manner+that+facilitates+the+RNAP+II+transition+into+the+elongation+stage+of+the+transcription+cycle. assertion.
- assertion asSentence ADH2+proved+to+have+ethanol+dehydrogenase+activity. assertion.
- assertion asSentence Arl1p+is+involved+in+the+anterograde+transport+from+the+Golgi+to+the+cell+surface+of+the+glycosylphosphatidylinositol+%28GPI%29-anchored+plasma-membrane-resident+protein+Gas1p. assertion.
- assertion asSentence Rpd3p+histone+deacetylase+participating+in+chromatin+remodeling+and+Rom2p+participating+in+the+cell+integrity+pathway+are+involved+in+the+control+of+PDR5+expression+and+modulation+of+multidrug+resistance+in+yeast. assertion.
- assertion asSentence Rfa2+serine+27+%28S27%29+is+required+for+Ime2-dependent+Rfa2+phosphorylation+in+vivo. assertion.
- assertion asSentence Tim15%2FZim17+cooperates+with+mtHsp70+to+facilitate+import+of+presequence-containing+proteins+into+the+matrix. assertion.
- assertion asSentence Myo2+drives+anterograde+mitochondrial+movements+in+budding+yeast+and+this+activity+is+supported+by+Ypt11+and+Mmr1. assertion.
- assertion asSentence Hyperpolarized+growth+of+Saccharomyces+cerevisiae+cak1P212S+and+cla4+mutants+weakens+cell+walls+and+renders+cells+dependent+on+chitin+synthase+3. assertion.
- assertion asSentence Ysl2p+represents+an+essential%2C+evolutionarily+conserved+member+of+a+network+controlling+direct+binding+and+membrane+docking+of+Ggas.. assertion.
- assertion asSentence Cch1+and+Mid1+mediate+the+ethanol-induced+Ca2%2B+flux. assertion.
- assertion asSentence GOR1+codes+for+glyoxalate+reductase+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence BNI1+and+BNR1+contribute+to+Bud6p-dependent+microtubule-cortex+interactions+by+controlling+Bud6p+localisation. assertion.
- assertion asSentence Nucleocytoplasmic+shuttling+of+Pik1p+involves+phosphorylation+and+14-3-3+proteins+bind+Pik1p+in+the+cytoplasm. assertion.
- assertion asSentence Ist1+has+a+dual+role+in+the+regulation+of+Vps4+activity. assertion.
- assertion asSentence In+unperturbed+cells%2C+Mrc1+interacts+independently+with+both+the+N-terminal+and+C-terminal+halves+of+Pol2+%28Pol2N+and+Pol2C%29. assertion.
- assertion asSentence A+direct+role+of+the+Dsl1+complex%2C+in+particular+Tip20p%2C+in+the+formation+and+stabilization+of+ER+SNARE+complexes. assertion.
- assertion asSentence FOL1+is+an+essential+gene+and+the+nongrowth+phenotype+of+the+fol1+deletion+leads+to+a+recessive+auxotrophy+for+folinic+acid+%285%27-formyltetrahydrofolate%29. assertion.
- assertion asSentence The+Rad50%2FMre11%2FXrs2+complex+is+responsible+for+rapid+processing+of+most+damaged+ends+into+substrates+that+subsequently+undergo+recombinational+repair. assertion.
- assertion asSentence GAL6+has+a+role+in+ethanol+tolerance. assertion.
- assertion asSentence The+N-terminal+prion+domain+of+the+Ure2+protein+is+unstructured+in+the+soluble+protein+and+does+not+have+a+specific+interaction+with+the+C-terminal+nitrogen+regulation+domain. assertion.
- assertion asSentence Ure2+protects+Saccharomyces+cerevisiae+from+heavy+metal+ion+and+oxidative+cellular+damage. assertion.
- assertion asSentence Ssu72+catalyzes+serine-5-P+dephosphorylation+subsequent+to+addition+of+the+7-methylguanosine+cap+on+pre-mRNA+in+a+manner+that+facilitates+the+RNAP+II+transition+into+the+elongation+stage+of+the+transcription+cycle. assertion.
- assertion asSentence Tight+connection+between+DNA+synthesis+and+histone+deposition+during+DNA+replication+mediated+by+H3K56ac%2FCAF1%2FRtt106+provides+a+mechanism+for+the+stabilization+of+advancing+replication+forks+and+the+maintenance+of+genome+integrity. assertion.
- assertion asSentence Involement+of+PSY2+in+the+DNA+damage+response. assertion.
- assertion asSentence Functions+of+Nud1p+are+connected+to+the+ability+of+Spc72p+to+bind+to+the+outer+plaque+and+half-bridge+%28via+Kar1p%29+of+the+SPB. assertion.
- assertion asSentence The+growth+impairment+of+cells+lacking+Npr1+on+many+nitrogen+sources+is+shared+by+cells+deprived+of+the+three+Mep+proteins+and+is+a+consequence+of+deficient+ammonium+retrieval. assertion.
- assertion asSentence Rho5p+is+a+target+of+Msi1p%2FNpr1p+regulation+and+the+regulatory+circuit+involving+phosphorylation+and+ubiquitination. assertion.
- assertion asSentence Rps3p+has+a+beta-lyase+activity+with+a+broad+range+of+substrate+specificity+which+cleaves+phosphodiester+bonds+of+UV+or+oxidatively+damaged+DNA+substrates. assertion.
- assertion asSentence Bni5+phosphorylation+is+important+for+interaction+with+septin+component+Cdc11+and+for+timely+delocalization+from+septin+filament+at+late+mitosis. assertion.
- assertion asSentence Cbk1+regulation+of+the+RNA-binding+protein+Ssd1+integrates+cell+fate+with+translational+control. assertion.
- assertion asSentence There+are+overlapping+kinetochore+targets+of+CK2+and+Aurora+B+kinases+in+mitotic+regulation+in+yeast. assertion.
- assertion asSentence The+Lsm1p-7p-Pat1p+complex+protects+mRNAs+by+binding+at%2Fnear+the+3%27end+and+distinguishes+between+oligoadenyLated+and+polyadenylated+RNA. assertion.
- assertion asSentence The+protein+factor-arrest+11+%28Far11%29+is+essential+for+the+toxicity+of+human+caspase-10+in+yeast+and+participates+in+the+regulation+of+autophagy+and+the+DNA+damage+signaling. assertion.
- assertion asSentence Nuclear-localisation+signal+and+catalytic+serine+235+are+necessary+for+the+proapoptotic+activity+of+Nma111. assertion.
- assertion asSentence The+stabilization+of+the+actin+cytoskeleton+caused+by+deletion+of+Sla1p+or+End3p+leads+to+hyperactivation+of+the+Ras+signaling+pathway. assertion.
- assertion asSentence The+expression+of+GPX1+is+induced+by+glucose+starvation+and+treatment+with+calcium+chloride+involving+the+Ras%2FcAMP+pathway+and+Snf1. assertion.
- assertion asSentence In+a+low-glucose+environment%2C+MDS3e+and+MKT1e+interacted+positively+to+confer+a+fitness+advantage. assertion.
- assertion asSentence Growth+on+glucose+requires+ATP+hydrolysis+in+mitochondria+and+recruits+Sal1p+as+a+Ca2%2B-dependent+mechanism+to+import+ATP-Mg+from+the+cytosol. assertion.
- assertion asSentence Mks1p+is+a+central+player+of+retrograde+signaling+%28RS%29+and+is+acted+upon+by+multiple+regulators+of+the+pathway. assertion.
- assertion asSentence COX5a+is+switched+off+and+COX5b+is+switched+on+when+the+O2+concentration+drops+below+a+threshold+of+0.5+microM+O2. assertion.
- assertion asSentence Peroxisomal+localization+and+function+of+NADP%2B+-specific+isocitrate+dehydrogenases+in+yeast. assertion.
- assertion asSentence Sis1+is+a+yeast+member+of+the+Type+II+Hsp40s+family+and+in+a+highly+conserved+alpha-helical+N-terminal+J-domain%2C+a+disordered+middle+region+%28divided+into+glycine%2Fphenylalanine+%28G%2FF%29+and+glycine%2Fmethionine+%28G%2FM%29+rich+regions%29+and+two+C-terminal+sub-domains. assertion.
- assertion asSentence The+slow+growth+of+cells+lacking+Dom34+and+haploinsufficient+for+a+protein+of+the+40S+subunit+is+caused+by+a+severe+shortage+of+40S+subunits+available+for+translation+initiation. assertion.
- assertion asSentence The+species-specific+amino-terminal+half+%28aa+1-63%29+plays+a+regulatory+role+in+transcriptional+regulation+and+the+carboxy-terminal+half+%28aa+64-149%29+is+involved+in+direct+binding+to+the+amino-terminal+portions+of+Med4+and+Med7+and+the+assembly+of+Med9. assertion.
- assertion asSentence Interaction+of+Tim23+with+Tim50+Is+essential+for+protein+translocation+by+the+mitochondrial+TIM23+complex. assertion.
- assertion asSentence Deletion+of+POP2+is+accompanied+by+an+increase+of+both+SLT2+and+KDX1+levels. assertion.
- assertion asSentence Tight+connection+between+DNA+synthesis+and+histone+deposition+during+DNA+replication+mediated+by+H3K56ac%2FCAF1%2FRtt106+provides+a+mechanism+for+the+stabilization+of+advancing+replication+forks+and+the+maintenance+of+genome+integrity. assertion.
- assertion asSentence Hsp90+and+the+cochaperone+Sba1%2Fp23+accumulate+in+the+nucleus+of+quiescent+Saccharomyces+cerevisiae+cells. assertion.
- assertion asSentence Two+aromatic+residues%2C+W352+and+W544%2C+localized+to+two+widely+separated%2C+conserved+motifs+of+Ddc1%2C+are+essential+for+Mec1+activation. assertion.
- assertion asSentence Mex67-Mtr2+export+receptor+employs+a+versatile+binding+platform+on+its+surface+that+can+create+a+crosstalk+between+mRNA+and+ribosome+export+pathways. assertion.
- assertion asSentence The+propeptide+of+yeast+cathepsin+D+inhibits+programmed+necrosis. assertion.
- assertion asSentence Required+for+double-strand+break-initiated+sister+chromatin+exchange+%28SCE%29+and+DNA+damage-associated+SCE+after+exposure+to+X-ray-mimetic+and+ultraviolet-mimetic+chemicals. assertion.
- assertion asSentence Threshold+levels+of+Rad53+activity+modulate+the+tolerance+to+alkylating+DNA+damage+at+least+by+controlling+the+abundance+of+the+key+TLS+factor+Rev1+bound+to+chromatin. assertion.
- assertion asSentence Kes1+%28Osh4p%29+associated+with+exocytic+vesicles+that+move+from+the+mother+cell+into+the+bud. assertion.