Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence A+nonsynonymous+polymorphism+in+RDS2+significantly+affects+oxidative+stress+survival+in+a+clinical+Saccharomyces+cerevisiae+isolate. assertion.
- assertion asSentence THe+copper+binding+site+is+co-translationally+formed+by+a+transient+interaction+between+Cox11+and+the+nascent+cytochrome+C+oxidase+in+the+intermembrane+space. assertion.
- assertion asSentence KAP120+functions+as+a+nuclear+import+receptor+for+ribosome+assembly+factor+RPF1. assertion.
- assertion asSentence The+Mgr2+is+a+coupling+factor+of+the+presequence+translocase+crucial+for+cell+growth+at+elevated+temperature+and+for+efficient+protein+import. assertion.
- assertion asSentence The+crystal+structure+of+yeast+PNGase+in+complex+with+N%2CN%27-diacetylchitobiose+%28chitobiose%29. assertion.
- assertion asSentence The+Elp3+FeS+cluster+is+essential+for+normal+Elongator+function+in+vivo+primarily+as+a+structural%2C+rather+than+catalytic%2C+domain. assertion.
- assertion asSentence Intermembrane+space+loop+of+mitochondrial+F1F0+ATP+synthase+subunit+4+is+a+main+component+of+the+peripheral+stalk+and+is+involved+in+dimerization%2Foligomerization+of+the+enzyme. assertion.
- assertion asSentence Interaction+of+Tim23+with+Tim50+Is+essential+for+protein+translocation+by+the+mitochondrial+TIM23+complex. assertion.
- assertion asSentence In+Srb10p+derivatives%2C+the+absence+of+CM-1+%26+CM-II+motifs+decreases+the+interaction+of+Srb10p+with+its+cyclin+partner+Srb11p+and+with+the+component+Tup1p+of+the+general+co-repressor+complex+Tup1p-Ssn6p. assertion.
- assertion asSentence Positive+or+negative+roles+of+different+cyclin-dependent+Pho85-cyclin+complexes+orchestrate+induction+of+autophagy+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Rmi1+forms+a+heteromeric+complex+with+Sgs1-Top3+in+yeast+and+plays+a+role+in+targeting+Sgs1-Top3+to+appropriate+substrates. assertion.
- assertion asSentence Nucleoporins+are+required+for+maintenance+of+proper+Ulp1+levels+at+nuclear+pore+complexes+and+for+the+establishment+of+the+appropriate+sumoylation+of+several+cellular+proteins. assertion.
- assertion asSentence Ctf19+and+Csm3+are+both+important+mediators+of+pericentromeric+cohesion. assertion.
- assertion asSentence Hat1p+plays+a+direct+role+in+DNA+damage+repair+and+is+responsible+for+specific+changes+in+histone+modification+that+occur+during+the+course+of+recombinational+DNA+repair. assertion.
- assertion asSentence Haa1p+is+required+for+a+more+rapid+adaptation+of+a+yeast+cell+population+to+several+weak+acid+food+preservatives. assertion.
- assertion asSentence The+Mcm4%2FMcm7+and+Mcm4%2FMcm6%2FMcm7+assemblies+can+open+to+load+onto+circular+DNA+to+initiate+unwinding. assertion.
- assertion asSentence A+defective+MCM+helicase+causes+genetic+instability+only+in+particular+cell+types. assertion.
- assertion asSentence The+phosphatidylethanolamine+level+of+yeast+mitochondria+is+affected+by+the+mitochondrial+components+OXA1+and+YME1. assertion.
- assertion asSentence The+behaviour+of+trehalase+mutant+strains+demonstrates+the+participation+of+trehalases+Nth1p%2C+Nth2p+and+Ath1p+in+the+mobilization+of+intracellular+trehalose+during+growth+recovery+after+saline+stress. assertion.
- assertion asSentence Blocked+exocytic+sorting+in+sro7Delta+mutants+gives+rise+to+quality+control-mediated+routing+of+Ena1p+to+the+vacuole. assertion.
- assertion asSentence eIF-5+can+form+the+multifactor+complex+with+the+ribosome+40S+subunit. assertion.
- assertion asSentence Interaction+between+the+Tah18+and+Dre2+C-terminus+is+essential+for+viability. assertion.
- assertion asSentence Hos1+deacetylates+Smc3+to+close+the+cohesin+acetylation+cycle. assertion.
- assertion asSentence MED1+is+indepently+recruited+by+the+activator+Met4. assertion.
- assertion asSentence In+the+presence+of+Ca2%2B%2C+the+active+sites+of+TK1+and+TK2+exhibit+negative+cooperativity+in+binding+both+xylulose-5-phosphate+and+ribose-5-phosphate+and+positive+cooperativity+in+the+catalytic+transformation+of+the+substrates. assertion.
- assertion asSentence mrl1+is+a+mitochondrial+factor+for+myo2p-dependent+inheritance+of+mitochondria. assertion.
- assertion asSentence TFIIB+interaction+with+the+CF1+complex+and+Pap1+is+crucial+for+gene+looping+and+transcriptional+regulation. assertion.
- assertion asSentence Asr1+is+a+RING+finger+ubiquitin-ligase+that+binds+directly+to+RNA+polymerase+II+via+the+carboxyl-terminal+domain+of+the+largest+subunit+of+the+enzyme. assertion.
- assertion asSentence Mrd1p+coordinates+key+events+in+biosynthesis+of+small+ribosome+subunits. assertion.
- assertion asSentence During+chromatid+cohesion+establishment%2C+Ctf4+is+found+at+the+DNA+replication+fork+and+travels+along+chromosomes+with+the+replication+fork. assertion.
- assertion asSentence Kar3p+contributes+to+spindle+stability+by+cross-linking+spindle+microtubules. assertion.
- assertion asSentence Residues+Phe77%2C+Ile115+and+Leu131+of+Sec3+bind+to+an+extended+hydrophobic+surface+formed+around+switch+regions+I+and+II+of+Rho1. assertion.
- assertion asSentence Ada2p+and+Gcn5p+regulates+transcription+and+DNA+repair+at+the+MET16+gene. assertion.
- assertion asSentence Vps46p+regulates+the+membrane+association+of+Vps4p+and+is+required+for+the+interaction+of+Vta1p+with+Vps32p%2FSnf7p+of+the+ESCRT-III+complex. assertion.
- assertion asSentence Assembly+of+a+Vps4p+oligomeric+complex+with+full+ATPase+activity+that+interacts+with+Vta1p+is+essential+for+normal+endosome+function. assertion.
- assertion asSentence Ist1+has+a+dual+role+in+the+regulation+of+Vps4+activity. assertion.
- assertion asSentence The+second+region+of+homology+%28SRH%29+function+of+Vps4+requires+an+intact+C-terminal+helix+and+is+important+for+assembly+and+intersubunit+catalysis+in+AAA+ATPases. assertion.
- assertion asSentence RIM101+pathway+contributes+to+cell+wall+assembly+and+its+function+becomes+essential+in+the+absence+of+SIt2. assertion.
- assertion asSentence Additional+mutational+suppressors+of+toopoisomerase+ii+defects. assertion.
- assertion asSentence Spo13+is+required+to+prevent+sister+kinetochore+biorientation+by+facilitating+the+recruitment+of+the+monopolin+complex+to+kinetochores+during+meiosis+1. assertion.
- assertion asSentence Spo13+destruction+in+anaphase+I+is+not+essential+for+meiosis. assertion.
- assertion asSentence The+Hos2p+complex+is+required+for+proper+activation+of+the+Mpk1p%2FSlt2p+cell+integrity+kinase+cascade. assertion.
- assertion asSentence RLM1+deletion+decreases+the+transcription+of+SLT2+encoding+the+Mpk1p+kinase. assertion.
- assertion asSentence Rrm3+helicase+facilitates+replication+through+the+transcription-dependent+replication+fork+pause+site+and+reduces+recombination. assertion.
- assertion asSentence The+intra-S+phase+checkpoint+protein+Tof1+collaborates+with+the+helicase+Rrm3+and+the+F-box+protein+Dia2+to+maintain+genome+stability+in+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Rrm3Delta+and+high+concentrations+of+hydroxyurea+suppressed+replication+slow+zone+expression+in+mec1-4ts+cells. assertion.
- assertion asSentence Vma10+%28subunit+G%29%2C+expressed+as+a+glutathione-S-transferase+fusion+protein+in+Escherichia+coli%2C+is+able+to+interact+strongly+with+Vma4p+%28subunit+E%29+expressed+in+a+cell-free+system. assertion.
- assertion asSentence Dissociation+of+the+Pho85p%2FPcl5p+complex+is+the+initial+step+in+Gcn4p+stabilization. assertion.
- assertion asSentence Localization+of+Pcl5+into+the+cytoplasm+prevents+the+degradation+of+Gcn4. assertion.
- assertion asSentence Upf2p+phosphorylation+is+crucial+for+nonsense-mediated+mRNA+decay+%28NMD%29+pathway. assertion.
- assertion asSentence Mei5-Sae3+is+a+mediator+of+Dmc1+assembly+during+meiotic+recombination+in+S.+cerevisiae. assertion.
- assertion asSentence tgs1Delta+cells+are+specifically+defective+in+splicing+SAE3+meiotic+pre-mRNAs. assertion.
- assertion asSentence KAP120+functions+as+a+nuclear+import+receptor+for+ribosome+assembly+factor+RPF1. assertion.
- assertion asSentence Snf1p-dependent+Spt-Ada-Gcn5-acetyltransferase+%28SAGA%29+recruitment+and+chromatin+remodeling+activities+on+the+HXT2+and+HXT4+promoters. assertion.
- assertion asSentence The+yeast+mitochondrial+1-Cys+Prx1+is+reactivated+by+glutathionylation+of+the+catalytic+cysteine+residue+and+subsequent+reduction+by+thioredoxin+reductase+%28Trr2%29+coupled+with+glutathione+%28GSH%29. assertion.
- assertion asSentence Histone+H2B+monoubiquitination+by+Rad6%2FBre1+is+required+for+the+trimethylation+of+both+histone+H3K4+and+H3K79+by+set1+methyltransferase. assertion.
- assertion asSentence The+C-terminal+tandem+BRCT+repeats+of+Rtt107+interaction+with+gammaH2A+is+functionally+important+during+DNA+repair. assertion.
- assertion asSentence DNA2+of+Saccharomyces+cerevisiae+selectively+unwinds+triplet+repeat+DNA. assertion.
- assertion asSentence Assembly+of+Snu114+into+U5+snRNP+requires+Prp8+and+a+functional+GTPase+domain. assertion.
- assertion asSentence Ctr2-1%2C+a+mutant+form+of+Ctr2+that+mislocalizes+to+the+plasma+membrane%2C+requires+the+Fre1+plasma+membrane+metalloreductase+for+Cu%28I%29+import. assertion.
- assertion asSentence Mdm31p+and+Mdm32p+control+mitochondrial+morphology+through+regulation+of+mitochondrial+cation+homeostasis+and+the+maintenance+of+proper+matrix+osmolarity. assertion.
- assertion asSentence Mutations+in+the+hydrophobic+core+of+ubiquitin+affect+its+recognition+by+RPN10. assertion.
- assertion asSentence Exopolyphosphatases+in+different+cell+compartments+of+Saccharomyces+cerevisiae. assertion.
- assertion asSentence Dynamics+of+yeast+exopolyphosphatase+%28scPPX%29catalysis+reveals+significant+functional+differences+between+structurally+similar+scPPX+and+family+II+pyrophosphatase. assertion.
- assertion asSentence Influence+of+carbon+source+on+the+activity+of+PPX1. assertion.
- assertion asSentence The+molecular+chaperone+Sse1+and+the+growth+control+protein+kinase+Sch9+collaborate+to+regulate+protein+kinase+A+signaling. assertion.
- assertion asSentence The+Sch9p+kinase+is+a+key+downstream+effector+of+oxidative+phosphorylation%2C+reactive+oxygen+species+metabolism+and+chronological+life+span+in+the+TOR-mitochondria+pathway. assertion.
- assertion asSentence Ase1p+and+Cin8p+affect+nuclear+positioning+through+astral+micro-tubule-dependent+mechanisms. assertion.
- assertion asSentence C-terminal+UBA+domain+of+Rad23+ubiquitin+receptor+protects+it+by+preventing+initiation+of+protein+degradation+at+the+proteasome. assertion.
- assertion asSentence DNA+runs+through+a+central+channel+in+the+double+hexamer%2C+and%2C+once+loaded%2C+Mcm2-7+can+slide+passively+along+double-stranded+DNA. assertion.
- assertion asSentence The+critical+amino+acid+sequence+of+Ssc1+and+Ssc3+that+can+%22make+or+break%22+mtHsp70+chaperone+function. assertion.
- assertion asSentence Basic+residues+required+for+phosphoinositide+binding+overlap+a+previously+mapped+binding+site+for+the+ArfGEF+Gea2p. assertion.
- assertion asSentence Simultaneous+recruitment+of+trans-activators+by+GCN4+stimulates+multiple+steps+of+transcription+in+vivo. assertion.
- assertion asSentence A+set+of+native+or+nativelike+tertiary+interactions%2C+distributed+throughout+the+entire+sequence%2C+collectively+stabilize+the+folding+transition+state+of+the+GCN4+coiled+coil. assertion.
- assertion asSentence eIF3+is+retained+on+ribosomes+throughout+uORF1+translation+and%2C+interacts+with+its+5%27+enhancer+at+the+mRNA+exit+channel+to+stabilize+mRNA+association+with+post-termination+40S+subunits+and+enable+resumption+of+scanning+for+reinitiation+downstream. assertion.
- assertion asSentence By+promoting+histone+H2B+lysine+123+ubiquitylation%2C+Paf1+represses+the+ARG1+gene+by+negatively+affecting+Gcn4+occupancy+at+the+promoter. assertion.
- assertion asSentence Nitrogen-responsive+regulation+of+GATA+protein+family+activators+Gln3+and+Gat1+occurs+by+two+distinct+pathways%2C+one+inhibited+by+rapamycin+and+the+other+by+methionine+sulfoximine. assertion.
- assertion asSentence Yen1+can+act+upon+recombination%2Frepair+intermediates+that+arise+in+MUS81-defective+cells+following+replication+fork+damage. assertion.
- assertion asSentence MSRA+and+MSRB+helps+to+preserve+the+function+of+cellular+FeS+clusters+from+oxidative+inactivation. assertion.
- assertion asSentence Not4+is+required+for+appropriate+association+of+the+Not5+subunit+of+the+Ccr4-Not+complex+with+polysomes+and+for+ubiquitination+of+Rps7A. assertion.
- assertion asSentence RAD51-dependent+BIR+does+not+require+special+facilitating+sequences+that+are+required+for+a+less+efficient+RAD51-independent+process. assertion.
- assertion asSentence Yeast+cells+lacking+the+SGS1+DNA+helicase+and+the+MUS81+structure-specific+endonuclease+display+a+synthetic+lethality+that+is+suppressed+by+loss+of+the+RAD51+recombinase. assertion.
- assertion asSentence Dmc1p+and+Rad51p+are+loaded+to+the+DNA+repair+site+in+an+independent+manner. assertion.
- assertion asSentence The+Slx5-Slx8+complex+functions+as+a+two-component+ubiquitin+ligase+and+controls+genome+stability+via+ubiquination. assertion.
- assertion asSentence Sho1p+plays+role+in+signal+transduction+pathway. assertion.
- assertion asSentence The+catalytic+subunit+of+the+budding+yeast+protein+phosphatase+1+%28PP1%29+homolog%2C+Glc7%2C+regulates+exit+from+the+spindle+checkpoint. assertion.
- assertion asSentence OXA1+complements+a+lack+of+yidC2+in+S.+mutans. assertion.
- assertion asSentence Spt2+is+required+for+the+major+chromatin+deposition+pathway+that+uses+old+histones+to+refold+nucleosomes+in+the+wake+of+RNA+polymerase+II+at+the+SRG1-SER3+locus. assertion.
- assertion asSentence Rad4%2C+a+Rad23-binding+protein%2C+regulates+ubiquitylated+substrate+turnover. assertion.
- assertion asSentence Disruption+of+UBP3+leads+to+enhanced+UV+resistance+and+elevated+Rad4+stability. assertion.
- assertion asSentence Cbk1+and+Bck2+are+required+for+Mpk1+activation+during+heat+shock+and+cell+wall+stress+and+for+Mpk1+dephosphorylation+during+heat+shock+adaptation. assertion.
- assertion asSentence Rad24-2+truncation+protein+affects+telomere+structure+or+recombination+in+a+manner+distinct+from+rad24-delta. assertion.
- assertion asSentence Acm1+and+Bmh1%2FBmh2+constitute+a+specialized+inhibitor+of+anaphase-promoting+complex%2FCCdh1. assertion.
- assertion asSentence Ffz2+is+a+plasma-membrane+sugar+transporter+that+transports+glucose+and+fructose+with+a+similar+affinity+and+velocity. assertion.
- assertion asSentence flgK+gene+in+Pectobacterium+carotovorum+subsp%2C+carotovorum+influences+cell+motility+and+leads+to+decreased+pathogenicity. assertion.
- assertion asSentence The+transcription+of+HdaA+is+directly+activated+by+DnaA%2C+providing+a+robust+feedback+regulatory+mechanism+that+adjusts+the+levels+of+HdaA+to+inactivate+DnaA. assertion.
- assertion asSentence The+efflux+pump+gene+hefA+plays+an+important+role+in+multidrug+resistance+of+H+pylori. assertion.
- assertion asSentence Pathway+made+by+Skp+and+DegP+chaperones+plays+a+secondary+role+in+periplasmic+transport+and+folding+of+the+N+region+of+intimin. assertion.
- assertion asSentence AphA+links+the+expression+of+virulence+and+biofilm+synthesis+genes. assertion.
- assertion asSentence Chemotaxis+signaling+protein+CheY+binds+to+the+rotor+protein+FliN+to+control+the+direction+of+flagellar+rotation+in+Escherichia+coli. assertion.