Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Cel45A+%28PAS_chr4_0643%29+is+highly+thermostable+at+80+degrees+C+for+6+h. assertion.
- assertion asSentence ZosA-mediated+zinc+transport+is+required+for+comK+expression. assertion.
- assertion asSentence The+different+catalytic+functions+of+PolX%28Bs%29+enable+it+to+perform+recognition+and+incision+at+an+AP+site+and+further+restoration+%28repair%29+of+the+original+nucleotide+in+a+standalone+AP-endonuclease-independent+way. assertion.
- assertion asSentence Jasmonic+acid+manipulation+by+Erwinia+amylovora+mainly+relies+on+the+type+III+effector+DspA%2FE. assertion.
- assertion asSentence OxyR+functions+as+a+transcriptional+repressor+of+the+catalase+gene+by+a+mechanism+that+is+independent+of+oxidative+stress+induced+by+H%282%29O%282%29. assertion.
- assertion asSentence MatA+switches+off+motility+by+repression+of+the+flagellar+master+operon+flhDC. assertion.
- assertion asSentence The+products+of+both+easC+%28catalase%29+and+easE+%28FAD-dependent+oxidoreductase%29+are+required+for+conversion+of+N-methyl-4-dimethylallyltryptophan+%28N-Me-DMAT%29+to+chanoclavine-I. assertion.
- assertion asSentence UGM+has+several+extra+secondary+and+tertiary+structural+elements+which+are+important+for+substrate+recognition+and+oligomerization. assertion.
- assertion asSentence rfbB+and+rfbC+are+involved+in+LPS+biosynthesis+and+efficient+attachment+to+maize+root+surface+and+colonization+of+internal+tissues. assertion.
- assertion asSentence The+depletion+of+mitochondrial+porin+reduced+cell+growth+of+the+procyclic+form+and+the+bloodstream+form. assertion.
- assertion asSentence L.+major+TAT+resembled+T.+cruzi+TAT+in+substrate+specificity. assertion.
- assertion asSentence Trypanosoma+have+a+conserved+Mago+and+a+divergent+Y14+protein. assertion.
- assertion asSentence Trypanosoma+have+a+conserved+Mago+and+a+divergent+Y14+protein. assertion.
- assertion asSentence Three+mitochondrial+DNA+polymerases+are+essential+for+kinetoplast+DNA+replication+and+survival+of+bloodstream+form+Trypanosoma+brucei. assertion.
- assertion asSentence The+requirement+for+ACC+in+T.+brucei+is+dependent+upon+the+growth+environment+in+two+different+life+cycle+stages. assertion.
- assertion asSentence Newly+synthesized+TbAGO1+is+required+to+support+an+efficient+RNAi+response. assertion.
- assertion asSentence SPS2+is+involved+in+oxidative+stress+protection+of+the+parasite. assertion.
- assertion asSentence Conditional+double+knockout+demonstrated+that+1-D-myo-inositol-3-phosphate+synthase+%28INO1%29+is+an+essential+gene+in+bloodstream-form+Trypanosoma+brucei. assertion.
- assertion asSentence The+kinesin-13+family+protein+TbKif13-2+has+only+a+marginal+impact+on+flagellar+length+in+T.+brucei. assertion.
- assertion asSentence Three+mitochondrial+DNA+polymerases+are+essential+for+kinetoplast+DNA+replication+and+survival+of+bloodstream+form+Trypanosoma+brucei. assertion.
- assertion asSentence RNA+pol+I+transcription+in+T.+brucei+does+not+require+the+RNA+pol+II+subunit+RPB7. assertion.
- assertion asSentence Mitochondrial+DNA+primase%28Tb927.1.4010%29+is+essential+for+cell+growth+and+kinetoplast+minicircle+DNA+replication. assertion.
- assertion asSentence PulS%2C+a+pilotin%2C+targets+secretin+PulD+monomers+through+the+periplasm+to+the+outer+membrane. assertion.
- assertion asSentence The+crystal+structure+of+the+Spa40+reveals+it+is+the+surface+features+in+this+region%2C+rather+than+the+cleavage+event+itself%2C+that+are+important+for+substrate+binding. assertion.
- assertion asSentence Deoxycholate+promotes+the+stable+recruitment+of+IpaB+to+the+needle+tip+where+it+colocalizes+with+IpaD. assertion.
- assertion asSentence This+vaccine+candidate+provides+better+safety+and+comparable+immunogenicity+to+bacillary+dysentery+in+rhesus+monkeys. assertion.
- assertion asSentence Raloxifene+exerted+direct+protective+effects+on+human+osteoblasts+in+both+estrogen+receptor+alpha%2Fbeta+dependent+and+independent+manners. assertion.
- assertion asSentence Triple-negative+breast+cancer+%28TNBC%29+are+larger+in+size+compared+with+other+subtypes+and+almost+all+grade+3. assertion.
- assertion asSentence Pelvic+organ+prolapse+is+associated+with+higher+expression+of+ERalpha%2FERbeta+in+the+pelvic+floor+of+both+pre-+and+post-menopausal+women. assertion.
- assertion asSentence Activation+of+estrogen-related+receptor+alpha+in+several+different+breast+cancer+cell+lines+leads+to+a+significant+increase+in+VEGF+mRNA+expression%2C+an+activity+that+translates+into+an+increase+in+VEGF+protein+secretion. assertion.
- assertion asSentence AP-2epsilon+and+Ets-1+are+involved+in+the+regulation+of+integrin+alpha10+transcription+in+chondrocytes. assertion.
- assertion asSentence MAPKAP+kinase+2+overexpression+is+associated+with+expression+of+p38+MAP+kinase+and+ETV1+in+gastrointestinal+stromal+tumors+%28GIST%29. assertion.
- assertion asSentence EZH2+mRNA+expression+in+circulating+epithelial+cells+represents+a+promising+marker+for+detecting+early+metastasis+in+prostate+cancer. assertion.
- assertion asSentence Lupus+anticoagulant+plays+a+role+in+the+binding+of+prothrombin+to+nonactivated+platelets. assertion.
- assertion asSentence Iron+ions+inhibit+the+ability+of+thrombin+to+form+fibrin+clots+in+blood+plasma. assertion.
- assertion asSentence Carriage+of+the+prothrombin+20210+mutation+is+related+to+an+increased+rate+of+liver+fibrosis+in+hepatitis+C+patients. assertion.
- assertion asSentence An+untranslated+RNA+plays+a+role+in+PAR-1+gene+expression+during+embryonic+growth. assertion.
- assertion asSentence Heparin+and+lepirudin+inhibit+thrombin-inducible+cleavage+and+internalization+of+PAR-1+and+platelet+activation+in+vitro+to+a+similar+extent. assertion.
- assertion asSentence Occupancy+of+EPCR+by+protein+C+switches+signaling+specificity+so+that+activation+of+PAR-1+by+thrombin+inhibits+TNF-alpha-mediated+synthesis+of+IL-6+and+IL-8+and+down-regulates+TGF-beta-mediated+expression+of+collagen+type+4+and+fibronectin. assertion.
- assertion asSentence Circulating+monocytes+of+asymptomatic+individuals+with+echolucent+lipid-rich+carotid+atherosclerosis+express+an+imbalance+between+TF+and+TFPI. assertion.
- assertion asSentence The+prevalence+of+FVL+differed+in+different+Arabic+cases. assertion.
- assertion asSentence Thrombin+generation+and+activated+protein+C+resistance+in+the+absence+of+factor+V+Leiden+are+risk+factors+for+recurrent+venous+thromboembolism. assertion.
- assertion asSentence Inhibition+of+FVIIa+with+small-molecule+active-site+inhibitors+represents+a+promising+antithrombotic+approach. assertion.
- assertion asSentence FX+binds+to+the+Adenovirus+5+hexon%2C+not+fiber%2C+via+an+interaction+between+the+FX+Gla+domain+and+hypervariable+regions+of+the+hexon+surface. assertion.
- assertion asSentence C.+trachomatis+can+productively+infect+liver+cells+and+utilize+FABP-transported+long-chain+fatty+acids+for+its+own+biosynthesis. assertion.
- assertion asSentence RNF8+and+FAAP20+%28C1orf86%29+are+needed+for+efficient+Fanconi+anemia+group+D2+protein+FANCD2+monoubiquitination. assertion.
- assertion asSentence The+Fc%28alpha%29RI+844+A%3EG+polymorphism+is+not+associated+with+systemic+sclerosis+or+rheumatoid+arthritis+sceptibility. assertion.
- assertion asSentence The+lipid+raft-associated+67LR+plays+an+important+role+in+mediating+the+FcepsilonRI-suppressive+action+of+EGCG. assertion.
- assertion asSentence Fc+gamma+RIIa+polymorphism+is+not+a+risk+factor+for+rheumatoid+arthritis. assertion.
- assertion asSentence FcgammaRIIA+can+be+activated+in+human+platelets+downstream+%5Bof%5DG-protein-coupled+receptors+by+low+concentrations+of+agonists. assertion.
- assertion asSentence Variation+in+FcGRIIa+predisposes+to+Graves+disease+and+further+supports+the+role+of+FcGRIIa+as+a+susceptibility+locus+for+autoimmune+diseases+in+general. assertion.
- assertion asSentence FcgammaRIIb+is+important+in+controlling+the+immune+response+to+malarial+parasites. assertion.
- assertion asSentence CN+of+FCGR3B+and+variations+in+are+important+in+SLE+pathogenesis. assertion.
- assertion asSentence Dual+recruitment+of+FcgammaRIIIa+and+the+IL-12R+to+lipid+raft+microdomains+allows+for+enhanced+activation+of+downstream+signaling+events+that+lead+to+IFN-gamma+production. assertion.
- assertion asSentence Antibody-dependent+cellular+cytotoxicity+is+inhibited+in+natural+killer+cells+from+therapy-naive%2C+HIV-infected+individuals+at+the+level+of+early+events+in+CD16+signal+transduction. assertion.
- assertion asSentence Individuals+with+high+percentage+of+CD14%28%2B%29+CD16%28%2B%29+demonstrated+significantly+lower+%28P%3C0.05%29+plasma+levels+on+the+IL-10. assertion.
- assertion asSentence FCN2+promoter+variants+%28-986G%3EA+and+-4A%3EG%29+influence+ficolin-2+serum+levels+and+susceptibility+to+schistosomiasis. assertion.
- assertion asSentence Position+83+in+FGF-1+is+thermodynamically+optimized+to+accept+a+free+cysteine. assertion.
- assertion asSentence Recombinant+human+FGF-2+alters+osteoblastic+expression+of+bone+morphogenetic+protein-2+and+Msx-2+in+vitro+to+favor+cellular+differentiation+and+osteoinduction. assertion.
- assertion asSentence The+fibroblast+growth+factor-2+binding+site+of+thrombospondin-1+is+located+in+the+type+III+repeats. assertion.
- assertion asSentence APO+can+enhance+the+biosynthesis+and+release+of+FGF-2+through+the+activation+of+the+MZF-1+transcription+factor+in+striatal+astrocytes. assertion.
- assertion asSentence Fibroblast+growth+factor-2+is+regulated+by+an+endogenous+antisense+RNA+and+by+argonaute-2. assertion.
- assertion asSentence Lacrimo-auriculo-dento-digital+syndrome+is+caused+by+reduced+activity+of+the+fibroblast+growth+factor+10+%28FGF10%29-FGF+receptor+2+signaling+pathway. assertion.
- assertion asSentence The+relative+concentrations+of+Anosmin-1+and+FGF-2+modulate+the+migration+of+oligodendrocyte+precursors+during+development+through+their+interaction+with+FGFR1. assertion.
- assertion asSentence FGFR3+has+a+dual+effect%2C+as+both+a+negative+and+a+ositive+regulator+of+the+endochondral+ossification+process+during+post-natal+bone+development. assertion.
- assertion asSentence The+miR-99a-mTOR%2FFGFR3+pathway+is+crucial+for+controlling+tumor+growth+in+a+wide+range+of+human+cancers+that+harbor+upregulation+of+the+Src-related+oncogenic+pathways. assertion.
- assertion asSentence FGFR2+recruits+Grb2+through+its+C-terminal+SH3+domain. assertion.
- assertion asSentence The+bFGF%2C+FGFR1%2F2+and+syndecan+1-4+expressions+are+altered+in+bladder+tumours. assertion.
- assertion asSentence Mitochondria+are+involved+in+the+apoptotic+activity+of+FHIT. assertion.
- assertion asSentence E2F-1+overexpression+plays+a+role+in+suppression+of+tumor%2C+at+least+in+part+trough+transcriptional+regulation+of+FHIT+and+relevant+activation+of+WWOX. assertion.
- assertion asSentence Nicotine+induces+methylation+of+the+FHIT+gene+followed+by+loss+of+Fhit+protein+expression+in+human+esophageal+squamous+epithelial+cells. assertion.
- assertion asSentence Concomitant+allelic+losses+of+the+BRCA1+and+FHIT+genes+are+associated+with+more+aggressive+breast+tumors. assertion.
- assertion asSentence FHL3+%28human+four-and-a-half+LIM-only+protein+3%29+interacts+with+human+phosphatase+CDC25B+in+the+cell+nucleus. assertion.
- assertion asSentence The+VEGF-D+serum+levels+are+reduced+in+patients+with+metastases+of+differentiated+thyroid+cancer%2C+regardless+of+the+degree+of+metastatic+spread. assertion.
- assertion asSentence Insertion+of+a+chaperone+domain+from+E.+coli+SlyD+converts+human+FKBP12+into+a+powerful+catalyst+of+protein+folding. assertion.
- assertion asSentence FKBP12+forms+an+endogenous+inhibitor+of+EGFR+phosphorylation+directly+involved+in+control+of+cellular+EGFR+activity+%28as+in+carcinoma%29. assertion.
- assertion asSentence FOXC2+is+a+susceptibility+locus+for+reduced+BMD+in+Japanese+men+and+women. assertion.
- assertion asSentence Overexpression+of+FoxM1+partially+protected+cancer+cells+from+the+thiazole+antibiotic-mediated+cell+death. assertion.
- assertion asSentence FoxM1+plays+an+important+role+in+the+resistance+of+non-small-cell+lung+cancer+cells+to+gefitinib+in+vitro. assertion.
- assertion asSentence FoxOs+have+emerged+as+an+important+effector+arm+of+PI3K%2FAkt+signaling+by+driving+multiple+apoptotic+gene+expression. assertion.
- assertion asSentence Nodal+signaling+promotes+cyclin+G2+transcription+by+upregulating+FoxO3a+expression%2C+inhibiting+FoxO3a+phosphorylation+and+enhancing+its+synergistic+interaction+with+Smads. assertion.
- assertion asSentence Deacetylation+of+FOXO3+by+SIRT1+or+SIRT2+facilitates+Skp2-mediated+FOXO3+poly-ubiquitination+and+proteasomal+degradation. assertion.
- assertion asSentence EWS%2FFLI1+induces+apoptosis%2C+at+least+partially%2C+through+the+activation+of+CASP3. assertion.
- assertion asSentence Targeting+VEGF+receptor+%28VEGFR%29-1-+or+VEGFR-2-expressing+cells+is+effective+in+controlling+the+osteoblastic+progression+of+PCa+in+bone. assertion.
- assertion asSentence The+presence+of+mutations+of+NPM1+and+FLT3-ITD+significantly+decreased+with+age+in+adult+acute+myeloid+leukemia. assertion.
- assertion asSentence Flt3+Ligand%28FL%29+gene+regulated+by+Egr-1+promoter+can+protect+hematopoiesis+from+5-Fu+injury. assertion.
- assertion asSentence Methylation+of+FMRP+affects+its+ability+to+bind+to+FXR1P+and+regulate+the+translation+of+FMRP+target+mRNAs. assertion.
- assertion asSentence FMR1+premutation+is+associated+with+deficits+in+general+intelligence+and+memory+among+older+males+with+symptoms+of+FXTAS. assertion.
- assertion asSentence Interaction+with+fibronectin+through+integrin+alpha5+plays+an+important+role+in+human+extravillous+trophoblast+invasion. assertion.
- assertion asSentence Mutations+in+fibronectin%2C+induce+anoikis+in+human+squamous+cell+carcinoma+cells+by+modulating+integrin+alpha+v-mediated+phosphorylation+of+FAK+and+ERK. assertion.
- assertion asSentence Neutrophil+gelatinase-associated+lipocalin+%28NGAL+or+lipocalin-2%29is+co-expressed+with+migration+stimulating+factor+%28MSF+or+FN1%29+by+keratinocytes+and+acts+as+a+functional+inhibitor+of+MSF. assertion.
- assertion asSentence A+molecular+complex+of+fibronectin+and+aggrecan+predicts+response+to+lumbar+ESI+for+radiculopathic+back+pain+with+HNP. assertion.
- assertion asSentence ITP-79+modulated+binding+of+TG2+to+fibronectin. assertion.
- assertion asSentence Fibronectin+1+%28FN1%29+is+a+promising+biomarker+candidate+for+clear+cell+renal+cell+carcinoma+%28RCC%29. assertion.
- assertion asSentence Bovine+dialyzable+leukocyte+extract+can+block+the+AP-1+DNA-binding+activity+and+expression+of+several+transcriptions+factors+in+breast+cancer+cells. assertion.
- assertion asSentence Site-specific+mTOR+phosphorylation+regulates+mTORC1+function. assertion.
- assertion asSentence Under+nutrient+sufficiency%2C+high+mTOR+activity+prevents+Ulk1+activation+by+phosphorylating+Ulk1+Ser+757+and+disrupting+the+interaction+between+Ulk1+and+AMPK. assertion.
- assertion asSentence The+miR-99a-mTOR%2FFGFR3+pathway+is+crucial+for+controlling+tumor+growth+in+a+wide+range+of+human+cancers+that+harbor+upregulation+of+the+Src-related+oncogenic+pathways. assertion.
- assertion asSentence PM02734+caused+inhibition+of+Akt%2FmTOR+signaling+pathways+and+the+activation+of+death-associated+protein+kinase+%28DAPK%29+by+dephosphorylation. assertion.
- assertion asSentence Temsirolimus+and+the+oral+everolimus%2C+exhibit+antitumor+effects+through+inhibition+of+the+mammalian+target+of+rapamycin+%28mTOR%29+pathway. assertion.