Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Type+I+IFN%2C+induced+by+c-jun%2C+primes+IFNgamma-mediated+immune+responses+by+regulating+expression+of+STAT1. assertion.
- assertion asSentence Kv1.4+expression+is+mediated+through+a+complex+interplay+between+many+distinct+RNA+regions. assertion.
- assertion asSentence Altered+electrophysiological+properties+of+TRN+neurons+contribute+to+the+reduced+EEG+power+at+slow+frequencies+in+the+thalamocortical+network+of+Kv3-deficient+mice. assertion.
- assertion asSentence KCNE1+channels+are+necessary+for+K%2B+secretion+in+developmental+Saccule+and+Utricle+in+mice. assertion.
- assertion asSentence Regulation+of+arterial+diameter+is+not+altered+in+mice+lacking+TREK-1. assertion.
- assertion asSentence The+current+is+mediated+via+TWIK-related+K%28%2B%29+channel+%28TREK%29-1+channels. assertion.
- assertion asSentence The+ring+of+negative+charge+in+BK+channels+facilitates+block+through+a+preferential+electrostatic+attraction+of+Mg2%2B+and+polyamine+over+K%2B. assertion.
- assertion asSentence VEGF%2C+acting+via+VEGFR2%2C+plays+a+critical+role+in+BP+control+by+promoting+NO+synthase+expression+and+NO+activity. assertion.
- assertion asSentence Eg5+is+essential+for+cell+division+early+in+mouse+development. assertion.
- assertion asSentence Kif3a+restrains+canonical+Wnt+signalling+both+by+restricting+the+CKI-dependent+phosphorylation+of+Dvl+and+through+a+separate+ciliary+mechanism. assertion.
- assertion asSentence Insulin+signaling+targets+the+engagement+or+initiates+the+movement+of+glutamate+transporter+4-containing+membranes+on+microtubules+via+KIF5B+through+a+phosphatidylinositol+3-kinase-independent+mechanism. assertion.
- assertion asSentence C-Kit+is+required+for+development+of+AHR+in+an+MC-independent+fashion. assertion.
- assertion asSentence Amyloid+precursor+protein+%28APP%29+levels+are+well-correlated+with+the+amount+of+the+light+chain+of+kinesin-1+%28KLC1%29. assertion.
- assertion asSentence The+transcription+factor+Klf1+mediates+preferential+co-associations+of+Klf1-regulated+genes+at+a+limited+number+of+specialized+transcription+factories. assertion.
- assertion asSentence Klf4+interacts+directly+with+Oct4+and+Sox2+when+expressed+at+levels+sufficient+to+induce+induced+pluripotent+stem+cells. assertion.
- assertion asSentence LPS+activates+the+kallikrein-kinin+system+in+the+choroid+plexus+via+autocrine+induction+of+IL-1beta+and+TNF-alpha. assertion.
- assertion asSentence Kallikrein+plays+an+antihypertensive+role+in+hyperaldosteronism. assertion.
- assertion asSentence Blockade+of+TGF-beta+signaling+and+activated+Ras+signaling+cooperate+to+promote+pancreatic+ductal+adenocarcinoma+progression. assertion.
- assertion asSentence NF-kappaB+functions+downstream+of+Ras+to+promote+epigenetic+downregulation+of+FBP1. assertion.
- assertion asSentence Mitochondrial+metabolism+and+mitochondrial+reactive+oxygen+species+generation+are+essential+for+Kras-induced+cell+proliferation+and+tumorigenesis. assertion.
- assertion asSentence Mice+bearing+parallel+null+mutations+in+the+adapter+proteins+Schnurri2+%28Shn2%29+and+Schnurri3+%28Shn3%29+exhibit+defects+in+patterning+of+the+axial+skeleton+during+embryogenesis. assertion.
- assertion asSentence Maf-B+mRNA+is+expressed+during+development+of+the+eyelid+closure+in+mice. assertion.
- assertion asSentence Lack+of+K8+confers+resistance+to+colonocyte+apoptosis+in+a+microflora-dependent+manner. assertion.
- assertion asSentence A+coreceptor+is+involved+in+L1-mediated+neurite+outgrowth. assertion.
- assertion asSentence The+absence+of+Lama1+has+an+impact+on+the+Bergmann+glia+scaffold+that+aberrantly+develops. assertion.
- assertion asSentence The+A2G78+and+A2G80+sites+play+functional+roles+as+heparan+sulfate-+and+alpha-dystroglycan-binding+sites+in+the+laminin+alpha2+chain+LG4-5+module. assertion.
- assertion asSentence LAMP-2A+organizes+at+the+lysosomal+membrane+into+protein+complexes+of+different+sizes. assertion.
- assertion asSentence SOCS-6+acts+as+a+negative+regulator+of+T+cell+activation+by+promoting+ubiquitin-dependent+proteolysis+of+p56%28lck%29. assertion.
- assertion asSentence Transgenic+overexpression+of+LXR-alpha+in+macrophages+has+significant+antiatherogenic+properties+in+LDL-receptor+deficient+mice. assertion.
- assertion asSentence PCSK9-nullmice+carried+more+LDLR+and+less+insulin+in+their+pancreas. assertion.
- assertion asSentence The+citrus+flavonoid+naringenin+ameliorates+the+dyslipidemia+in+Western-fed+low-density+lipoprotein+receptor-null+mice%2C+leading+to+decreased+atherosclerosis. assertion.
- assertion asSentence Chinese+yellow+wine+and+red+wine+can+inhibit+MMP-2+and+improve+atherosclerosis+in+LDL+receptor+knockout+mice. assertion.
- assertion asSentence LEF-1+modulates+positively+the+proliferation+of+lymphocytes+induced+by+their+interaction+with+endothelial+cells. assertion.
- assertion asSentence Leptin%2C+acting+from+the+luminal+side%2C+controls+the+function+of+mucus-secreting+goblet+cells. assertion.
- assertion asSentence Chronic+leptin+deficiency+in+vivo+increases+seizure+susceptibility. assertion.
- assertion asSentence Leptin+regulation+during+hypoxia+in+vivo+depends+at+least+in+part+on+the+modulating+role+of+insulin. assertion.
- assertion asSentence Brainstem-derived+serotonin+favors+bone+mass+accrual+following+its+binding+to+Htr2c+receptors+on+ventromedial+hypothalamic+neurons+and+appetite+via+Htr1a+and+2b+receptors+on+arcuate+neurons. assertion.
- assertion asSentence Heat+stress+improves+leptin+and+adiponectin+signalling+in+adipose+tissue%2C+muscle+and+liver. assertion.
- assertion asSentence Leucine+affects+leptin+receptor+expression+in+muscle+cells+via+the+mTOR+signaling+pathway. assertion.
- assertion asSentence Galectin-3+deficiency+causes+alterations+in+the+expression+of+various+genes+associated+with+carcinogenesis+and+lipid+metabolism. assertion.
- assertion asSentence L3%2FLhx8+is+a+key+factor+in+the+cholinergic+differentiation+of+embryonic+stem+cells+and+is+involved+in+basal+forebrain+development. assertion.
- assertion asSentence L3%2FLhx8+is+a+key+factor+for+cholinergic+differentiation+of+murine+ES+cell-derived+spheres+and+is+involved+in+basal+forebrain+development. assertion.
- assertion asSentence Lhx8+is+regionally+enriched+in+the+Basal+Nucleus+of+Meynert+of+mouse+brain. assertion.
- assertion asSentence Constitutive+activation+of+the+Rho-ROCK-LIM+kinase+pathway+by+extracellular+production+of+lysophosphatidic+acid+by+the+action+of+autotaxin+is+required+to+maintain+the+large+size+of+lysosomes+in+visceral+endoderm+cells. assertion.
- assertion asSentence Retinoblastoma+protein+degradation+in+Lmna-%2F-+cells+occurs+by+gankyrin+and+MDM2-independent+mechanisms. assertion.
- assertion asSentence LMO4+promotes+the+acquisition+of+cortical+neuronal+identities+by+forming+a+complex+with+NGN2+and+subsequently+activating+NGN2-dependent+gene+expression. assertion.
- assertion asSentence Cells+in+the+hippocampal+granule+cell+layer+of+LOXL+-%2F-+mice+have+significantly+smaller+somas+and+muted+long-term+potentiation+compared+to+LOXL+%2B%2F%2B+mice. assertion.
- assertion asSentence Inhibition+of+the+cystic+fibrosis+transmembrane+conductance+regulator+reduced+cell-associated+annexin+A1+by+promoting+release+of+the+protein+in+microparticles. assertion.
- assertion asSentence Annexin+A1+plays+a+role+in+myogenic+differentiation. assertion.
- assertion asSentence High+concentrations+of+free+fatty+acids+as+present+in+the+plasma+of+LPL-deficient+mice+lead+to+pancreatic+cell+damage+and+are+high+risk+factors+for+the+development+of+acute+pancreatitis. assertion.
- assertion asSentence LRP1+modulates+both+the+expression+and+protein+levels+of+TGF-beta2+in+macrophages. assertion.
- assertion asSentence LTC%284%29+synthase%2C+thought+to+be+specific+for+the+conjugation+of+GSH+to+LTA%284%29%2C+can+also+recognize+5-oxoETE+as+an+electrophilic+substrate. assertion.
- assertion asSentence AAV-mediated+latexin+transduction+or+administration+of+a+small+molecule+carboxypeptidase+A+inhibitor+significantly+reduced+acetone-evoked+nociceptive+behavior+after+SNI. assertion.
- assertion asSentence Transcription+of+the+Ly49+genes+expressed+in+lymphoid+cells+is+achieved+in+a+manner+that+does+not+require+classical+upstream+promoters. assertion.
- assertion asSentence CCR6%2B+IL-17A-producing+gammadelta+T+cells+derive+from+less+TCR-dependent+selection+events+than+IFN-gamma-producing+NK1.1%2B+gammadelta+T+cells. assertion.
- assertion asSentence Cell-associated+CD93+regulates+leukocyte+recruitment+and+complement+activation+during+murine+peritonitis. assertion.
- assertion asSentence EpCAM+is+involved+in+signal+transduction+triggering+several+intracellular+signalling+pathways+using+tumor+cell+lines+in+colorectal+and+lung+cancer. assertion.
- assertion asSentence Arkadia+targets+Ski-bound%2C+inactive+phospho-Smad2%2F3+to+regulate+positively+Myostatin%2FTGF-beta+signaling. assertion.
- assertion asSentence Arkadia+targets+Ski-bound%2C+inactive+phospho-Smad2%2F3+to+regulate+positively+Myostatin%2FTGF-beta+signaling. assertion.
- assertion asSentence Peptidyl-prolyl+isomerase+Pin1+Associates+with+Smad3+and+Smad6. assertion.
- assertion asSentence Smad4+is+essential+for+catagen+induction+and+acts+as+a+critical+suppressor+in+skin+tumorigenesis. assertion.
- assertion asSentence The+Mc1r%28e%29+mutation+affects+the+proliferation+and+differentiation+of+melanocytes+and+l-tyrosine+rescues+the+reduced+proliferative+and+differentiative+activities. assertion.
- assertion asSentence Peripherally+administered+melanocortin+receptor+3%2F4+agonists+regulate+body+weight%2C+liver+metabolism+and+glucose+homeostasis+through+independent+pathways. assertion.
- assertion asSentence MK+and+HB-GAM+are+involved+in+stem+cells+maintenance%2C+cytodifferentiation+and+mineralization+processes+during+mouse+incisor+development. assertion.
- assertion asSentence The+CD98+system+is+independent+of+the+interleukin-2%2FIL-2R+system+in+murine+T+lymphocyte+activation. assertion.
- assertion asSentence Expression+of+miR-184%2C+a+brain-specific+microRNA+repressed+by+the+binding+of+MeCP2+to+its+promoter%2C+is+upregulated+by+the+release+of+MeCP2+after+depolarization. assertion.
- assertion asSentence Environmental+enrichment+alters+locomotor+behaviour+and+ventricular+volume+in+Mecp2+1lox+mice. assertion.
- assertion asSentence ANT1+protein+levels+are+upregulated+in+Mecp2-null+mice. assertion.
- assertion asSentence MEF2C%2C+or+genes+containing+MEF2+DNA-binding+sites%2C+is+required+for+the+efficient+differentiation+of+cardiomyoblasts+into+cardiomyocytes. assertion.
- assertion asSentence Menin+and+pRb+function+in+a+common+pathway+of+tumor+suppression. assertion.
- assertion asSentence Meox1+and+Meox2+genes+function+together+and+upstream+of+several+genetic+hierarchies+that+are+required+for+the+development+of+somites. assertion.
- assertion asSentence Eomes+promotes+formation+of+cardiovascular+progenitors+by+directly+activating+the+bHLH+transcription+factor+gene+Mesp1+upstream+of+the+core+cardiac+transcriptional+machinery. assertion.
- assertion asSentence The+activation+of+hepatocyte+growth+factor%2Fc-Met+signaling+is+a+major+pathway+involved+type+II+cell+proliferation+induced+by+ultrafine+carbon+black. assertion.
- assertion asSentence MFG-E8-dependent+signaling+stimulates+cell+proliferation+and+the+acquisition+of+mesenchymal+properties+and+contributes+to+mammary+carcinoma+development. assertion.
- assertion asSentence Mouse+embryonic+stem+cell+differentiation+in+vitro+is+dependent+on+the+SCF-KIT+pathway%2C+contrasting+with+the+apparently+normal+differentiation+of+KIT+null+inner+cell+mass+or+epiblast+cells+in+vivo. assertion.
- assertion asSentence Macrophage+migration+inhibitory+factor-deficient+cells+exhibit+E2F-dependent+growth+alterations+and+reduced+susceptibility+to+oncogenic+transformation+due+to+reduced+binding+of+E2F+to+retinblastoma+protein. assertion.
- assertion asSentence MIF+participates+in+type+1+diabetes+by+controlling+the+functional+activity+of+monocytes%2Fmacrophages+and+T+cells+and+modulating+their+secretory+capacity+of+pro-+and+anti-inflammatory+molecules. assertion.
- assertion asSentence Deletion+of+MIF+attenuates+neuronal+death+and+promotes+functional+recovery+after+compression-induced+spinal+cord+injury+in+mice. assertion.
- assertion asSentence MIF-induced+early+DC+maturation+and+IL-12+production+mediate+resistance+to+T.+gondii+infection. assertion.
- assertion asSentence MIF+performs+a+crucial+role+in+wound+healing+on+the+ocular+surface+after+the+induction+of+chemical+burns. assertion.
- assertion asSentence MIF+and+CD74+play+previously+unappreciated+roles+in+CCL2-induced+macrophage+adhesion+and+migration. assertion.
- assertion asSentence D-DT+is+a+MIF-like+cytokine. assertion.
- assertion asSentence Microphthalmia-associated+transcription+factor+regulates+B+cell+homeostasis+by+suppressing+the+antibody-secreting+fate. assertion.
- assertion asSentence MITF+and+SgIGSF+appear+essential+for+the+development+and+survival+of+mast+cells+in+tissues+of+adult+WBB6F1-KitW%2FKitW-v+mice. assertion.
- assertion asSentence Miz1+is+required+for+early+embryonic+development+during+gastrulation. assertion.
- assertion asSentence MNK2+plays+a+unique+role%2C+not+shared+by+its+closest+paralog+MNK1%2C+in+limiting+protein+translation+through+its+negative+effect+on+eIF4G+Ser1108+phosphorylation+and+p70S6K+activation. assertion.
- assertion asSentence In+mouse+keratinocytes+MMP-13+gene+expression+can+be+induced+through+a+Runx-independent+pathway+that+involves+the+ERK-dependent+modulation+of+AP-1. assertion.
- assertion asSentence Chinese+yellow+wine+and+red+wine+can+inhibit+MMP-2+and+improve+atherosclerosis+in+LDL+receptor+knockout+mice. assertion.
- assertion asSentence Antigen+challenge+via+the+airway+activates+Gr-1%28%2B%29+cells+and+consequently+MMP+to+facilitate+the+recruitment+of+Th+cells+in+the+airway+inflammatory+response. assertion.
- assertion asSentence MMP8+is+an+important+player+in+atherosclerosis. assertion.
- assertion asSentence Activation+of+peroxisome+proliferator+activated+receptor-gamma+ameliorates+the+mitochondrial+translocation+of+NOX-4+and+matrix+metalloproteinase-9+activation. assertion.
- assertion asSentence Tretinoin+is+essential+to+augment+MMP-9+expression+in+myeloid+dendritic+cells+and+can+alter+their+surface+expression+of+adhesion+molecules. assertion.
- assertion asSentence MMP-9+contributes+to+the+development+of+early+brain+damage+after+subarachanoid+hemorrhage+by+promoting+cerebral+edema+formation. assertion.
- assertion asSentence SDF-1+and+MMP-9+function+independently+to+promote+the+trafficking+of+myeloid+cells+into+the+injured+cord. assertion.
- assertion asSentence MMP-9+plays+an+important+role+in+the+development+of+parenchymal+hemorrhage+and+necrosis+in+the+small+remnant+liver+post+hepatectomy. assertion.
- assertion asSentence Sox15%2C+Fhl3+and+Foxk1+function+to+coordinately+regulate+the+myogenic+progenitor+cell+population+and+skeletal+muscle+regeneration. assertion.
- assertion asSentence Mnt-Myc+antagonism+plays+a+fundamental+role+in+regulating+cell+cycle+entry+and+proliferation. assertion.
- assertion asSentence The+absence+of+CD200R+signaling+inhibits+outgrowth+of+an+endogenous+skin+tumor+irrespective+of+CD200+expression+by+the+tumor+cells. assertion.
- assertion asSentence Mpl+is+an+active+player+during+the+first+steps+of+definitive+hematopoiesis+establishment+through+direct+regulation+of+the+expression+of+transcription+factors+or+genes+important+for+the+self-renewal%2C+proliferation+and+apoptosis+of+HSCs. assertion.
- assertion asSentence Nitric+oxide+and+MPO+contribute+in+liver+tissue+lipid+peroxidation+in+peritonitis. assertion.