Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+CD4+coreceptor+mediates+tolerance-inducing+signals+when+triggered+by+an+appropriate+ligand+in+vivo. assertion.
- assertion asSentence Involvement+of+the+CD4+extracellular+domain+for+the+inhibitory+effect+of+oxidative+stress+on+activation-induced+CD4+down-regulation+in+T+cells. assertion.
- assertion asSentence Present+and+functional+on+natural+killer+%28NK%29+cells%2C+CD4+plays+a+role+in+innate+immune+responses+as+a+chemotactic+receptor+and+by+increasing+cytokine+production. assertion.
- assertion asSentence gp120%2FCD4+interactions+are+the+main+driving+force+of+the+formation+of+cellular+contacts+between+infected+and+uninfected+CD4+T+cells+whereby+HIV+transmission+occurs. assertion.
- assertion asSentence A+strong+correlation+between+CD4+single+nucleotide+polymorophism+and+increased+susceptibility+to+HIV-1+infection+among+Kenyan+female+prostitutes. assertion.
- assertion asSentence Expression+of+Nef+causes+a+decrease+in+the+association+of+p56%28lck%29+with+cell+surface-expressed+CD4. assertion.
- assertion asSentence Reciprocal+modulation+of+circulating+CD4%2BCD25%2Bbright+T+cells+induced+by+extracorporeal+photochemotherapy+in+cutaneous+T-cell+lymphoma+and+chronic+graft-versus-host-disease+patients. assertion.
- assertion asSentence Crystal+structure+of+HIV-1+primary+receptor+CD4+in+complex+with+a+potent+antiviral+antibody. assertion.
- assertion asSentence Stromal+down-regulation+of+macrophage+CD4%2FCCR5+expression+and+NF-kappaB+activation+mediates+HIV-1+non-permissiveness+in+intestinal+macrophages. assertion.
- assertion asSentence Endocytosis+of+HIV-1+into+plasmacytoid+dendritic+cells+is+CD4-+and+dynamin-dependent. assertion.
- assertion asSentence Neutralizing+antibodies+to+the+conserved+CD4+binding+site+exert+selection+pressure+on+the+conserved+CD4bs+epitope+of+HIV-1+Env. assertion.
- assertion asSentence Individuals+with+latent+Mycobacterium+tuberculosis+infection+harbored+high+frequencies+of+late-stage+differentiated+%28CD45RA%28-%29CD27%28-%29%29+antigen-specific+effector+memory+CD4%28%2B%29+T+cells+that+expressed+PD-1. assertion.
- assertion asSentence The+N%2FC+termini+and+the+inner+domain+beta-sandwich+and+layer+2+support+the+noncovalent+association+of+gp120+trimer+with+the+CD4. assertion.
- assertion asSentence CD5+supports+the+survival+of+B+cells+by+stimulating+IL-10+production+and+by+concurrently+exerting+negative+feedback+on+BCR-induced+signaling+events+that+can+promote+cell+death. assertion.
- assertion asSentence CD5+is+rapidly+recruited+at+the+immunological+synapse+%28IS%29+and+lowers+the+T+cell+response+elicited+by+antigen+presentation+by+targeting+downstream+signaling+events+without+affecting+IS+formation. assertion.
- assertion asSentence T+lymphocyte+activation-induced+cell+death+%28AICD%29+in+response+to+a+cognate+tumor+is+inversely+proportional+to+the+surface+expression+level+of+CD5. assertion.
- assertion asSentence Alternative+costimulation+via+CD5%2C+rather+than+classic+costimulation+via+CD28%2C+primes+naive+T+cells+for+stable+Th17+development+through+promoting+the+expression+of+IL-23R. assertion.
- assertion asSentence Engagement+of+CD6+with+CD166+on+tumor+cells+plays+an+important+role+in+gammadelta+T+cell+activation+by+tumor+cells+sensitized+with+nonpeptide+antigens+endogenously+or+exogenously. assertion.
- assertion asSentence Cd6+is+a+signaling+attenuator+whose+expression+alone%2C+i.e.+in+the+absence+of+ligand+engagement%2C+is+sufficient+to+restrain+signaling+in+T+cells. assertion.
- assertion asSentence p32+recruits+ganciclovir+kinase+to+redistribute+the+nuclear+lamina. assertion.
- assertion asSentence LNX1+and+LNX2+interact+with+CD8alpha+and+promote+its+ubiquitylation+and+endocytosis. assertion.
- assertion asSentence Nef-mediated+down-modulation+of+CD8alphabeta+is+a+fundamental+property+of+primate+lentiviruses. assertion.
- assertion asSentence CD9+expression+can+be+used+to+predict+childhood+TEL%2FAML1-positive+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence CD9-deficiency+leads+to+impaired+localization+of+talin1+to+focal+adhesions+and+correlates+with+increased+motility+of+breast+cancer+cells. assertion.
- assertion asSentence A+marker+on+monocytes+that+can+differentiate+into+several+distinct+mesenchymal+cell+lineages. assertion.
- assertion asSentence Soluble+CD14+is+associated+with+aortic+stiffness+independently+of+age%2C+BP+and+atherosclerosis+in+humans. assertion.
- assertion asSentence No+association+between+the+CD14%2FC-159T+polymorphism+and+increased+risk+for+the+development+of+rheumatoid+arthritis. assertion.
- assertion asSentence The+existence+of+a+mutation+in+the+CD14+gene+is+associated+with+an+increased+susceptibility+to+ulcerative+colitis. assertion.
- assertion asSentence The+CD14%2F-260+and+CD14%2F-651+promoter+polymorphisms+are+associated+with+atopic+hypersensitivity+prevalence+among+young+adults+exposed+to+farm+environments. assertion.
- assertion asSentence Myeloid+zinc+factor-1+is+involved+in+a+calcitriol-induced+signaling+pathway+leading+to+myeloid+cell+differentiation+and+activation+of+CD11b+and+CD14. assertion.
- assertion asSentence In+patients+with+type+1+diabetes+mellitus%2C+the+CD14+C-260TT+homozygous+genotype+increases+the+risk+for+the+development+of+celiac+disease. assertion.
- assertion asSentence High+affinity+interactions+between+the+palmitoyl-oleoyl-phosphatidylglycerol+and+the+Toll-like+receptor+4-interacting+proteins+CD14+and+MD-2. assertion.
- assertion asSentence Expression+of+CD14+in+patients+with+TT%2C+TC+genotype+is+much+higher+than+those+in+burn+patients+with+CC+homozygote. assertion.
- assertion asSentence C%28-260%29T+polymorphism+in+the+promoter+of+CD+14+gene+is+not+associated+with+myocardial+infarction. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+of+CD14%2C+IL-13+and+IL-4+receptor+are+associated+with+hexamethylene+diisocyanate+asthma. assertion.
- assertion asSentence The+promoter+polymorphism+at+-159+C%2FT+of+the+CD14+gene+is+positively+associated+with+IBD%2C+both+ulcerative+colitis+and+Crohn%27s+disease. assertion.
- assertion asSentence Coligation+of+the+B+cell+antigen+receptor+with+the+complement+%28C3%29-binding+CD21%2FCD19%2FCD81+costimulatory+complex+can+enhance+the+escape+of+human+B+cells+from+Fas-induced+death. assertion.
- assertion asSentence Activation+of+B+cells+by+anti-sIgM+or+anti-CD19+antibodies+also+leads+to+cell+aggregation+that+is+promoted+by+CEACAM1%2C+also+in+a+PI3K-dependent+manner. assertion.
- assertion asSentence Ca%282%2B%29+down-regulates+SLC+and+CD19+gene+expression+upon+pre-BCR+activation+through+inhibition+of+E2A+by+Ca%282%2B%29%2Fcalmodulin. assertion.
- assertion asSentence Anti-CD22+recombinant+immunotoxin+moxetumomab+pasudotox+has+activity+in+relapsed%2Frefractory+hairy+cell+leukemia. assertion.
- assertion asSentence Functionally+differentiated+Vgamma9delta2%2B+T+cells+lack+CD27+expression+and+are+found+in+reduced+numbers+in+immunocompromised+hosts+%28such+as+healthy+newborns+and+HIV-infected+adults%29+and+during+active+pulmonary+tuberculosis. assertion.
- assertion asSentence Interaction+of+CD70+with+CD27+plays+a+direct+role+in+T+cell+activation+mediated+by+IL-2. assertion.
- assertion asSentence Expression+defines+phenotypic+stages+in+B+cell+precursor+development. assertion.
- assertion asSentence T+cells+grafted+with+a+recombinant+CD28%2FCDzeta+signaling+receptor+secrete+high+amounts+of+IL-2+upon+antigen+binding+without+exogenous+B7%2FCD28+costimulation%2C+demonstrating+that+complete+T+cell+activation+can+be+delivered+by+one+chimeric+receptor+molecule. assertion.
- assertion asSentence CD28+gene+region+is+associated+with+genetic+susceptibility+to+celiac+disease+in+UK+families. assertion.
- assertion asSentence Human+postthymic+regulatory+T+cells+require+CD28+costimulation+to+expand+and+maintain+potent+suppressive+function+in+vivo. assertion.
- assertion asSentence Functional+integrity+of+CD28+receptor+p56lck+transgene+and+plasma+membrane+lipid+rafts+are+all+prerequisites+for+up-regulation+and+long-term+expression+of+Foxp3+mRNA+transcripts+in+CD4positive25%28high%29Foxp3positive+regulatory+T+cell+precursors. assertion.
- assertion asSentence Relationship+between+CD28+gene+polymorphisms+and+renal+transplant+outcomes+by+genotyping+kidney+transplant+outcome+and+healthy+controls. assertion.
- assertion asSentence CD28-induced+RelA+is+a+key+transcription+factor+of+FOXP3+expression+in+human+CD4%28%2B%29CD25%28-%29+T+cells. assertion.
- assertion asSentence Loss+of+CD28+expression+is+associated+with+systemic+immunosuppression+related+to+cervical+cancer+progression. assertion.
- assertion asSentence Upregulation+in+the+colonic+mucosa+of+patients+with+ulcerative+colitis. assertion.
- assertion asSentence The+identical+effects+of+B7-1+and+B7-2+on+regulation+of+human+IL-2+gene+transcription+factors+NF-kappa+B+and+AP-1. assertion.
- assertion asSentence A+key+mechanism+in+the+pathogenesis+of+MS+is+the+increased+expression+of+CD86+and+CD40L+and+the+increased+production+of+IL12+during+disease+progression. assertion.
- assertion asSentence Engagement+of+B7-1%2FB7-2+molecules+on+human+indoleamine+2%2C3-dioxygenase+%28IDO%29-positive+dendritic+cells+delivers+a+signal+that+is+obligately+required+for+the+triggering+of+IDO+activity+during+antigen+presentation. assertion.
- assertion asSentence IL-2+upregulates+CD86+expression+on+human+CD4%28%2B%29+and+CD8%28%2B%29+T+cells+via+a+receptor-dependent+mechanism+that+involves+the+NFAT+and+mammalian+target+of+rapamycin+pathways. assertion.
- assertion asSentence Pretransplant+soluble+CD30+is+a+more+accurate+predictor+of+acute+rejection+when+compared+with+panel+reactive+antibodiees+in+kidney+transplantation. assertion.
- assertion asSentence Pre-transplant+serum+CD30+is+not+a+useful+biomarker+for+predicting+either+acute+rejection+or+recipient+survival+after+heart+transplantation. assertion.
- assertion asSentence Examine+CD30+expression+and+proliferative+fraction+in+nontransformed+mycosis+fungoides. assertion.
- assertion asSentence Regulation+of+myeloid+cell+proliferation+and+survival+by+p75%2FAIRM1+and+CD33+surface+receptors. assertion.
- assertion asSentence Specific+induction+of+CD33+expression+by+E2A-HLF+is+associated+with+acute+Lymphoblastic+Leukemia. assertion.
- assertion asSentence Preeclampsia+involves+changes+in+the+gene+expression+of+SIGLEC6+in+placental+cytotrophoblasts. assertion.
- assertion asSentence Regions+between+10+to+18+kb+upstream+and%2For+17+to+26+kb+downstream+of+the+human+CD34+gene+contain+critical+elements+for+human+CD34+expression+in+vivo. assertion.
- assertion asSentence CD34+immunoreactivity+closely+parallel+both+the+different+morphologic+steps+of+melanocytic+tumor+progression+and+the+presence+of+histological+parameters+related+to+the+aggressive+behaviour. assertion.
- assertion asSentence VEGF+appeared+more+common+as+compared+to+CD+34+in+early+liver+fibrosis. assertion.
- assertion asSentence Human+cord+blood+CD34%28%2B%29+cells+cocultured+with+murine+cardiomyocytes+formed+cells+that+exhibited+excitation-contraction+coupling+features+similar+to+those+of+cardiomyocytes. assertion.
- assertion asSentence Coculture+with+human+stromal+cells+induced+expression+of+CD34+and+CXCR4+on+CB+Lin%28-%29CD34%28-%29+cells. assertion.
- assertion asSentence S1P%281%29+acts+as+an+inhibitor+of+CXCR4-dependent+migration+of+hematopoietic+cells+to+sites+of+SDF-1+production. assertion.
- assertion asSentence The+CD34%2B+cell+concentration+in+peripheral+blood+predicts+CD34%2B+cell+yield+in+the+leukapheresis+product. assertion.
- assertion asSentence The+exacerbated+arthritis+disease+phenotype+in+Cd34-deficient+bone+marrow+chimeric+mice+is+due+to+an+increase+in+vascular+leakage+at+the+onset+of+disease+in+the+joint+and+implicates+CD34+as+a+regulator+of+vascular+permeability. assertion.
- assertion asSentence The+expressions+of+CD31+and+CD34+are+not+correlated+with+tumor+grade+and+stage+in+chromophobe+or+papillary+renal+cell+carcinoma. assertion.
- assertion asSentence Human+embryonic+stem+cells-derived+CD34%28%2B%29CD73%28-%29+cells+can+serve+as+mesenchymal+stem%2Fstromal+cells+progenitor+cells+with+the+ability+to+differentiate+into+adipocytes%2C+osteoblasts+and+chondrocytes. assertion.
- assertion asSentence Polygonal+CD34+positivity+portends+trichilemmal+differentiation. assertion.
- assertion asSentence ZFP36L1+negatively+regulates+erythroid+differentiation+by+directly+binding+the+3%27+untranslated+region+of+Stat5b+encoding+mRNA. assertion.
- assertion asSentence CD34+antigen-positive+cells+are+found+as+frequently+as+balloon+cells+and+are+associated+with+abnormal+reconstitution+of+the+cortex+in+epileptic+patients+with+glioneuronal+lesions. assertion.
- assertion asSentence A+redox-dependent+conformational+fraction+of+CD36%2C+localized+in+the+CD36+C-terminal+cysteine-rich+region%2C+mediates+cytoadherence+of+Plasmodium+falciparum-infected+erythrocytes+to+CD36-expressing+cells+and+is+inducible+by+low+toxicity+reducing+agents. assertion.
- assertion asSentence Adhesion+of+dendritic+cells+derived+from+CD34%2B+progenitors+to+resting+human+dermal+microvascular+endothelial+cells+is+down-regulated+upon+maturation+and+partially+depends+on+CD11a-CD18%2C+CD11b-CD18+and+CD36. assertion.
- assertion asSentence Expression+of+the+monocyte-macrophage+LDL+scavenger+receptor+CD36+is+increased+in+people+with+diabetes+mellitus%2C+type+2. assertion.
- assertion asSentence Expression+in+melanoma+cells+is+regulated+by+NSAIDs. assertion.
- assertion asSentence Lipoprotein+abnormalities+in+human+genetic+CD36+deficiency+is+associated+with+insulin+resistance+and+abnormal+fatty+acid+metabolism. assertion.
- assertion asSentence Resistin+promotes+lipid+accumulation+in+human+macrophages+through+its+upregulating+CD36+cell+surface+expression. assertion.
- assertion asSentence SNPs+in+the+CD36+gene+modify+the+effects+of+fish+oil+on+fasting+plasma+TAG%2C+NEFA%2C+glucose+LDL+and+HDL+cholesterol+concentrations+in+healthy%2C+middle-aged%2C+Caucasian+men. assertion.
- assertion asSentence VAR4+of+Plasmodium+falciparum+is+not+involved+in+CD36+adhesion. assertion.
- assertion asSentence CD36+gene+promoter+polymorphisms+are+associated+with+low+density+lipoprotein-cholesterol+in+normal+twins+and+after+a+low-calorie+diet+in+obese+subjects. assertion.
- assertion asSentence CD36+protein+genetic+variants+is+positively+associated+with+increased+risk+of+metabolic+syndrome+X+in+egyptian+adults. assertion.
- assertion asSentence There+is+an+association+between+HaeIII+polymorphism+of+scavenger+receptor+class+B+type+I+gene+and+plasma+HDL-cholesterol+concentration+in+patients+with+CAD. assertion.
- assertion asSentence Plays+a+major+role+in+the+clearance+of+apoptotic+cells+from+the+thymus. assertion.
- assertion asSentence PI3K+activation+stimulates+hepatic+SR-BI+function+post-translationally+by+regulating+the+subcellular+localization+of+SR-BI+in+a+P13K-dependent+manner. assertion.
- assertion asSentence SR-BI+plays+a+crucial+role+in+mediating+the+first+steps+of+hepatitis+C+virus-dendritic+cell+interaction+and+represents+a+cell+surface+receptor+for+HCV+entry+into+dendritic+cells. assertion.
- assertion asSentence SR-BI+significantly+boosts+hepatocyte+permissiveness+to+Plasmodium+entry+and+promotes+parasite+development. assertion.
- assertion asSentence Hepatitis+C+infections+can+be+blocked+by+specific+antibodies+against+scavenger+receptor+class+B+type+I+in+a+dose-dependent+manner. assertion.
- assertion asSentence SRBI+protein+has+an+independent+effect+on+high-density+lipoprotein+cholesterol+levels+in+women+with+hyperalphalipoproteinemia. assertion.
- assertion asSentence Scavenger+receptor+BI+%28SR-BI%29+has+a+prominent+role+in+cell-to-cell+transmission+of+neutralizing+antibody+resistant+Hepatitis+C+virus. assertion.
- assertion asSentence Glycine+dimerization+motif+in+the+N-terminal+transmembrane+domain+of+the+high+density+lipoprotein+receptor+SR-BI+required+for+normal+receptor+oligomerization+and+lipid+transport. assertion.
- assertion asSentence Impairment+of+the+ABCA1+and+SR-BI-mediated+cholesterol+efflux+pathways+and+HDL+anti-inflammatory+activity+in+Alzheimer%27s+disease. assertion.
- assertion asSentence CD38%2C+a+negative+prognostic+marker+in+B-cell+chronic+lymphocytic+leukemia+%28B-CLL%29%2C+plays+a+role+in+neoplastic+B-cell+growth+and+survival. assertion.
- assertion asSentence The+level+of+CD38+expression+on+different+T-cell+subsets+is+differentially+upregulated+in+drug-naive+HIV-infected+patients. assertion.
- assertion asSentence Biological+rationale+for+the+poor+prognosis+of+CD38%28%2B%29+for+chronic+lymphocytic+anemia+patients. assertion.
- assertion asSentence CD38+expression+have+independent+prognostic+value+in+early+stage+chronic+lymphocytic+leukaemia+%28CLL%29. assertion.
- assertion asSentence Expression+of+CD38+antigen+and+ZAP-70+have+an+exceptional+significance+in+the+prediction+of+prognosis+in+CLL+patients. assertion.
- assertion asSentence Capacity+of+NTPDase1+to+hydrolyze+both+nucleoside+triphosphates+and+diphosphates. assertion.