Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Phosphorylation+of+I-2+is+catalyzed+by+cdk1%3A%3AcyclinB1+and+staining+with+a+specific+antibody+should+prove+useful+as+a+selective+marker+of+cells+in+the+early+stages+of+mitosis. assertion.
- assertion asSentence Partial+or+complete+loss+of+Lzts1+downregulates+Cdc25C+and+inhibits+Cdk1+activity+during+mitosis%2C+leading+to+premature+transition+from+metaphase+to+anaphase. assertion.
- assertion asSentence Cyclin+A+assembles+with+Cdk1+only+after+complex+formation+with+Cdk2+reaches+a+plateau+during+late+S+and+G2+phases. assertion.
- assertion asSentence Accumulation-deficient+drug-resistance+mediated+by+RLIP76+can+be+modulated+by+inhibition+of+RLIP76+transport+activity+by+cdc2. assertion.
- assertion asSentence Cdk1+activity+is+required+to+initiate+checkpoint+signaling. assertion.
- assertion asSentence Cdc14B-dependent+modulation+of+Cdc25+phosphatase+and+Cdk1%2Fcyclin+B+activity+is+linked+to+correct+chromosome+segregation+and+bipolar+spindle+formation%2C+processes+that+are+required+for+proper+progression+through+mitosis+and+maintenance+of+genomic+stability. assertion.
- assertion asSentence The+ICER+is+phosphorylated+by+the+mitotic+kinase+cdk1. assertion.
- assertion asSentence Cdk1%2Fcyclin+B1-dependent+hyper-phosphorylation+of+Bim+during+prolonged+mitotic+arrest+is+an+important+cell+death+signal. assertion.
- assertion asSentence Cdk1+inhibition+induces+both+apoptosis+and+sarcoma-associated+herpesvirus+reactivation+in+a+primary+effusion+lymphoma+cells. assertion.
- assertion asSentence A+central+region+in+hnRNP-M+is+required+for+interaction+with+CDC5L%2FPLRG1. assertion.
- assertion asSentence SEPT7+plays+an+important+role+in+the+glioma+cell+invasion. assertion.
- assertion asSentence SEPT7+is+involved+in+the+regulation+of+sperm+maturation. assertion.
- assertion asSentence Sept7+occupies+the+ends+of+hexameric+building+blocks+which+assemble+into+non-polarised+filaments. assertion.
- assertion asSentence The+Cdc6+G1321A+polymorphism+is+associated+with+decreased+risk+of+cancer. assertion.
- assertion asSentence Human+CDC6+physically+interacts+with+ATR%2C+a+crucial+checkpoint+kinase%2C+in+a+manner+that+is+stimulated+by+phosphorylation+by+Cdk+and+the+CDC6-ATR+interaction+is+conserved+in+Xenopus. assertion.
- assertion asSentence There+is+no+interaction+between+RASSF1A+and+Cdc20. assertion.
- assertion asSentence The+degradation+of+Cdc20+represents+a+critical+control+mechanism+to+ensure+inactivation+of+APC%2FC%28Cdc20%29+in+response+to+the+spindle+assembly+checkpoint. assertion.
- assertion asSentence Spindle+assembly+checkpoint+protein+Cdc20+transcriptionally+activates+expression+of+ubiquitin+carrier+protein+UbcH10. assertion.
- assertion asSentence Caulibugulone+inhibition+of+cellular+Cdc25A+and+B+phosphatases+occurred+through+at+least+two+different+mechanisms%2C+leading+to+pronounced+cell+cycle+arrest. assertion.
- assertion asSentence Arsenite+slows+S+phase+progression+via+inhibition+of+cdc25A+dual+specificity+phosphatase+gene+transcription. assertion.
- assertion asSentence Chk1+is+the+primary+signal+transducer+linking+activation+of+the+ATM%2FATR+kinases+to+Cdc25A+destruction+in+response+to+ionizing+radiation. assertion.
- assertion asSentence A+caspase-dependent+cleavage+of+CDC25A+is+a+central+step+linking+cyclin-dependent+kinase+2+activation+with+non-genotoxic+apoptotic+induction. assertion.
- assertion asSentence 14-3-3+subtypes+can+control+the+subcellular+localization+of+CDC25B+by+binding+to+a+specific+site. assertion.
- assertion asSentence The+mitotic+phosphorylation+of+Ser%28321%29+acts+to+maintain+full+activation+of+Cdc25B+by+disrupting+14-3-3+binding+to+Ser%28323%29+and+enhancing+the+dephosphorylation+of+Ser%28323%29+to+block+14-3-3+binding+to+this+site. assertion.
- assertion asSentence CDC25B+forms+a+close+association+with+Ctn-2+proteins+at+the+centrosome. assertion.
- assertion asSentence Cdc42%2FRac1-dependent+activation+of+the+p21-activated+kinase+%28PAK%29+regulates+human+platelet+lamellipodia+spreading. assertion.
- assertion asSentence Upregulation+during+arachidonic+acid+mediated+HeLa+cell+adhesion. assertion.
- assertion asSentence Activation+of+the+small+Rho+GTPase+Cdc42+plays+a+specific+role+in+the+actin+reorganization+mediated+by+CD28+in+human+T+cells. assertion.
- assertion asSentence The+reorganization+of+actins+into+podosomes+is+controlled+by+CDC42+GTP-binding+protein. assertion.
- assertion asSentence Cdc42+synergistically+with+Rac1+induces+lamellipodia+and+membrane+ruffles+in+EGF-stimulated+cells. assertion.
- assertion asSentence The+two+unique+glutamates+in+Cdc42+and+basic+region+of+WASp+generate+favorable+electrostatic+steering+forces+that+control+the+accelerated+WASp-Cdc42+association+reaction. assertion.
- assertion asSentence Cdc42+regulates+AJ+permeability+by+controlling+the+binding+of+alpha-catenin+with+beta-catenin+and+the+consequent+interaction+of+the+VE-cadherin%2Fcatenin+complex+with+the+actin+cytoskeleton. assertion.
- assertion asSentence Efficient+phagosomal+maturation+and+the+subsequent+eradication+of+ingested+microbes+in+human+neutrophils+is+dependent+on+a+strictly+regulated+Cdc42+pathway. assertion.
- assertion asSentence ITSN-2L%2C+a+guanine+nucleotide+exchange+factor+for+Cdc42%2C+regulates+different+steps+of+caveola+endocytosis+in+ECs+by+controlling+the+temporal+and+spatial+actin+polymerization+and+remodeling+sub-adjacent+to+the+plasma+membrane. assertion.
- assertion asSentence Cdc42-GDP+can+inhibit+TC21+activation+by+RasGRF+GEFs%2C+demonstrating+that+Cdc42+negatively+affects+the+functions+of+RasGRF+GEFs+irrespective+of+the+GTPase+being+targeted. assertion.
- assertion asSentence Phosphorylation+of+Cdc42+at+Ser-71%2C+exemplarily+induced+by+epidermal+growth+factor%2C+reduces+Clostridium+difficile+toxin+A-induced+changes+in+the+intestinal+barrier+function. assertion.
- assertion asSentence Internalization+of+DENV-2+into+endothelial+cells+requires+viral+induction+of+dynamic+filopodia+regulated+by+Rac1+and+Cdc42+cross-talk+and+myosin+II+motor+activities. assertion.
- assertion asSentence Activation+of+Cdc42+GTPase+through+p210%28Bcr-Abl%29+tyrosine+kinase+signaling+in+CML+cells+contributes+to+defects+in+SDF-1alpha-chemotactic+response+due+to+desensitization+of+the+actin+polarization+signal+required+for+directional+migration. assertion.
- assertion asSentence Cdc42+regulates+the+uropod+through+CD11b+signaling+to+maintain+polarity+in+migrating+neutrophils. assertion.
- assertion asSentence Expression+of+constitutively+active+Cdc42+decreasea+RhoA-GTP+level+in+human+lung+microvascular+lymphatic+endothelial+cells. assertion.
- assertion asSentence Important+role+played+by+Cdc42+in+CCL19-induced+migration+and+invasion+of+squamous+cell+carcinoma+of+the+head+and+neck+cells. assertion.
- assertion asSentence Interaction+of+the+Salmonella+Typhimurium+SopB+with+host+Cdc42+is+involved+in+intracellular+replication. assertion.
- assertion asSentence Cdc42+enhances+the+resistance+of+colon+cancer+cells+to+several+antitumor+drugs. assertion.
- assertion asSentence The+SLUG+zinc-finger+protein+represses+E-cadherin+in+breast+cancer. assertion.
- assertion asSentence CAS%2FCSE+1+stimulates+E-cadhrin-dependent+cell+polarity+in+HT-29+human+colon+epithelial+cells. assertion.
- assertion asSentence E-cadherin+promoter+is+subject+to+epigenetic+control+in+colorectal+ulceration+and+plays+a+role+in+the+progression+from+chronic+inflammation+to+colorectal+cancer. assertion.
- assertion asSentence Intragenic+deletion+of+CDH1+is+the+activating+mechanism+of+the+wild-type+allele+in+hereditary+diffuse+gastric+carcinoma. assertion.
- assertion asSentence E-cadherin+and+calretinin+are+sensitive+and+specific+in+differential+diagnosis+of+benign+and+malignant+serous+effusion+specimens. assertion.
- assertion asSentence The+E-Cadherin%2C+the+main+system+of+adherens+junction%2C+present+in+the+tight+junctions+in+HepG2+cells. assertion.
- assertion asSentence CDHE+expression+is+repressed+in+the+lower+crypt+of+small+intestine+and+is+a+biological+marker+of+functional+relevance. assertion.
- assertion asSentence The+entire+cadherin-catenin+complex+is+involved+when+assessing+its+prognostic+value+in+colonic+adenocarcinom. assertion.
- assertion asSentence Cell-to-cell+communication+mediated+by+E-cadherin+contributes+to+the+acquirement+of+a+cardiomyogenic+phenotype+of+human+endothelial+progenitor+cells. assertion.
- assertion asSentence CDH1+mutations+are+associated+with+a+risk+of+early-onset+gastric+cancer. assertion.
- assertion asSentence The+expression+of+TGF-beta1+and+E-cadherin+are+correlated+with+lymph+node+metastasis+in+supraglottic+larynx+squamous+cell+carcinoma. assertion.
- assertion asSentence Roles+of+E-cadherin+and+beta-catenin+complexes+in+signet+ring+cell+carcinoma+of+the+lung+differ+from+their+roles+in+gastric+or+colorectal+cancers. assertion.
- assertion asSentence The+C%2FA+polymorphism+of+CDHE+has+a+direct+effect+on+the+risk+of+diffuse+gastric+cancer+at+young+age+in+Mexican+population. assertion.
- assertion asSentence The+abnormal+expression+of+CDX%282%29+and+E-cadherin+plays+an+important+role+in+the+development+of+gastric+carcinoma. assertion.
- assertion asSentence Vpu+leads+to+the+depression+of+both+total+and+beta-catenin-associated+E-cadherin+levels+through+beta-TrCP-dependent+stabilization+of+the+transcriptional+repressor+Snail. assertion.
- assertion asSentence E-cad%2C+CD44v6+and+PCNA+play+important+roles+in+invasion+and+metastasis+of+non-small+cell+lung+cancer+%28NSCLC%29. assertion.
- assertion asSentence N-glycosylation+at+Asn-633+is+essential+for+E-cadherin+expression%2C+folding+and+trafficking. assertion.
- assertion asSentence E-cadherine+and+CD44+immunoexpression+in+oral+squamous+cell+carcinoma+as+prognosis+factors. assertion.
- assertion asSentence Rather+than+being+translocated+to+the+nucleus+for+regulating+the+target+gene+transcription%2C+Smad7-stabilized-beta-catenin+is+shunted+to+the+E-cadherin+complex+to+modulate+cell-cell+adhesion. assertion.
- assertion asSentence Tissue+and+urine+expression+of+E-cadherin+in+bladder+transitional+cell+carcinoma+are+very+closely+associated+with+the+biological+behavior+of+the+neoplasm. assertion.
- assertion asSentence E-cadherin+plays+an+important+role+in+uterine+receptivity. assertion.
- assertion asSentence In+polarized+epithelial+cells%2C+E-cadherin+regulates+AMPK+phosphorylation+by+controlling+the+localization+of+the+LKB1+complex. assertion.
- assertion asSentence The+overexpression+of+epithelial+cell+adhesion+molecule+and+reduced+expression+of+E-cadherin+in+combination+is+more+significant+than+a+single+marker+for+predicting+poor+survival. assertion.
- assertion asSentence In+squamous+cell+lung+cancer+or+lung+adenocarcinomas%2C+the+abnormal+cytoplasmic+expression+of+p120ctn+isoform+1+always+correlates+to+the+abnormal+expression+of+E-cadherin. assertion.
- assertion asSentence Cadherin+can+be+used+to+discriminate+between+high-+and+low-risk+papillomavirus+in+urethral+cytologic+specimens. assertion.
- assertion asSentence E-cadherin+expression+predicts+precancerous+lesions+of+the+larynx. assertion.
- assertion asSentence Inactivation+and+disassembly+of+the+anaphase-promoting+complex+during+human+cytomegalovirus+infection+is+associated+with+degradation+of+the+APC5+and+APC4+subunits+and+does+not+require+UL97-mediated+phosphorylation+of+Cdh1. assertion.
- assertion asSentence The+epigenetic+change+in+E-Cadherin+and+Cyclooxygenase-2+is+associated+with+chronic+periodontitis. assertion.
- assertion asSentence Germline+CDH1+mutation+can+be+cosegregated+with+ILBC+in+the+absence+of+DGC. assertion.
- assertion asSentence Kras%28G12D%29+allele+promotes+metastasis+in+pancreatic+cancer+cells+partly+through+the+downregulation+of+E-cadherin. assertion.
- assertion asSentence Fyn%2C+a+member+of+Src+family+tyrosine+kinases%2C+plays+a+critical+role+in+mediating+TGF-beta1-induced+down-regulation+of+E-cadherin+in+human+A549+lung+cancer+cells. assertion.
- assertion asSentence Loss+of+E-cadherin+is+associated+with+triple-negative+breast+cancer. assertion.
- assertion asSentence H1+and+PAR2+receptors+enhance+delivery+of+immune-competent+cells+and+molecules+by+interrupting+E-cadherin+adhesion+in+lung+epithelial+cells. assertion.
- assertion asSentence Negative%2Flow+HER2+expression+alone+or+combined+with+E-cadherin+positivity+is+predictive+of+better+prognosis+in+Tunisian+patients+with+breast+carcinoma. assertion.
- assertion asSentence Hakai+dimerization+allows+the+formation+of+a+phosphotyrosine-binding+pocket+that+recognizes+specific+phosphorylated+tyrosines+and+flanking+acidic+amino+acids+of+Src+substrates%2C+such+as+E-cadherin%2C+cortactin+and+DOK1. assertion.
- assertion asSentence Associations+between+RASSF1A+and+CDH1+methylation+levels+and+clinico-pathological+parameters+manifested+various+levels+of+RASSF1A+and+CDH1+promoter+methylation. assertion.
- assertion asSentence Loss+of+E-cadherin+is+associated+with+liposarcoma. assertion.
- assertion asSentence Protein+phosphatase+Dusp26+associates+with+KIF3+motor+and+promotes+N-cadherin-mediated+cell-cell+adhesion. assertion.
- assertion asSentence N%2FE-+cadherin+expression+profile+has+a+significant+prognostic+value+in+invasive+bladder+cancer. assertion.
- assertion asSentence IGF-1+released+from+corneal+epithelial+cells+up-regulates+the+expression+of+N-cadherin+in+corneal+fibroblasts. assertion.
- assertion asSentence The+PX-RICS-14-3-3zeta%2Ftheta+complex+couples+N-cadherin-beta-catenin+with+dynein-dynactin+to+mediate+its+export+from+the+endoplasmic+reticulum. assertion.
- assertion asSentence Neural+cadherin+mediates+cell+to+cell+adhesion+and+signal+transduction+with+early+osteoblastic+differentiation. assertion.
- assertion asSentence Cadherin+2+is+required+for+regulation+of+somal+translocation+of+neurons+in+the+neocortex. assertion.
- assertion asSentence Twist+is+an+upstream+regulator+of+N-cadherin-mediated+invasion+of+human+trophoblastic+cells. assertion.
- assertion asSentence A+short+truncated+50+kDa+form+of+the+N-terminal+part+of+P-cadherin+expresses+in+melanoma+cell+lines+compared+to+melanocytes+and+keratinocytes. assertion.
- assertion asSentence EGFR%2C+fibrillin-2%2C+P-cadherin+and+AP2beta+as+biomarkers+for+rhabdomyosarcoma+diagnostics. assertion.
- assertion asSentence Aberrant+demethylation+of+CDH3+is+associated+with+colorectal+carcinomas. assertion.
- assertion asSentence P-cadherin+and+CD24+are+expressed+in+carcinomas+of+the+biliary+tract+with+high+frequency+and+at+an+early+stage+of+carcinogenesis. assertion.
- assertion asSentence Human+Schlemm%27s+canal+cells+express+the+endothelial+adherens+proteins%2C+VE-cadherin+and+PECAM-1. assertion.
- assertion asSentence Upon+infection+by+spotted+fever+group+rickettsiae%2C+phosphorylation+of+VE-cadherin+directly+attenuates+homophilic+protein-protein+interactions+at+the+endothelial+adherens+junctions+dysfunction+causing+microvascular+hyperpermeability. assertion.
- assertion asSentence T-cad+mediates+low-density+lipoprotein-initiated+cell+proliferation+via+the+Ca%282%2B%29-tyrosine+kinase-Erk1%2F2+pathway. assertion.
- assertion asSentence Loss+of+T-cadherin+due+to+5%27+CpG+island+methylation+is+associated+with+colon+carcinoma. assertion.
- assertion asSentence CDX2+and+LI-cadherin+are+sensitive+markers+of+intestinal+metaplasia+with+or+without+dysplasia+in+the+upper+gastrointestinal+tract. assertion.
- assertion asSentence LI+cadherin+is+associated+with+an+intestinal+phenotype+and+an+%27intestinal+pathway%27+of+carcinogenesis+in+intraductal+papillary+mucinous+neoplasm. assertion.
- assertion asSentence Interferon+gamma+reduces+the+activity+of+Cdk4+and+Cdk2%2C+inhibiting+he+G1+cell+cycle+in+human+hepatocellular+carcinoma+cells. assertion.
- assertion asSentence Inhibition+of+CDK2+kinase+by+indole-3-carbinol+is+accompanied+by+selective+alterations+in+cyclin+E+composition. assertion.
- assertion asSentence Bim-mediated+apoptosis+following+actin+damage+due+to+deregulation+of+Cdk2+and+the+cell+cycle+by+the+absence+of+functional+p53. assertion.