Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+overexpression+of+p16+in+uterine+serous+carcinoma+is+unrelated+to+HPV. assertion.
- assertion asSentence p16%28INK4a%29+is+a+valuable+biomarker+for+detection+of+HPV-related+dysplastic+squamous+cells. assertion.
- assertion asSentence Inactivation+of+CDKN2A+and+B+genes+constitute+an+important+step+in+chordoma+development. assertion.
- assertion asSentence Lowered+p16+expression+represented+an+unfavourable+prognostic+index+in+ovarian+cancer. assertion.
- assertion asSentence Founder+deletion+%28p16-Leiden%29+in+Dutch+melanoma+families+does+not+account+for+the+atypical+nevus+phenotype+that+segregates+in+both+p16-Leiden+carriers+and+non-carriers+and+is+a+risk+factor+and+a+precursor+lesion+for+melanoma. assertion.
- assertion asSentence Mitochondrial+p32%2FC1QBP+is+a+critical+mediator+of+p14ARF-induced+apoptosis. assertion.
- assertion asSentence The+nucleolar+p19%28ARF%29+is+incapable+of+inducing+autophagy+from+within+the+nucleolus. assertion.
- assertion asSentence Underexpression+of+p16+is+associated+with+lymph+node+metastases+in+laryngeal+squamous+cell+carcinoma. assertion.
- assertion asSentence Can+initiate+a+cyclin-dependent+kinase+%28CDK%294-+or+CDK6-dependent+autonomous+senescence+program+that+is+disabled+by+inherited+melanoma-associated+mutations. assertion.
- assertion asSentence CDKN2A+deletion+is+associated+with+acute+lymphoblastic+leukaemia. assertion.
- assertion asSentence Deletion+of+chromosome+9p21.3+is+found+in+a+many+primary+cutaneous+diffuse+large+B-cell+lymphoma%2C+leg+type+patients+and+inactivation+of+the+CDKN2A+gene+is+associated+with+an+unfavorable+prognosis. assertion.
- assertion asSentence Polymorphisms+in+the+p16+gene+is+associated+with+significantly+poorer+response+to+treatment+in+pancreatic+cancer+patients. assertion.
- assertion asSentence Hypermethylation+of+p16%28INK4A%29+promoter+is+one+of+the+epigenetic+factors+affecting+the+progress+of+sporadic+breast+carcinogenesis+in+Iranian+patients. assertion.
- assertion asSentence Aberrant+promoter+methylation+and+reduced+expression+of+p16+gene+is+associated+with+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence P16+protein+is+closely+related+with+the+occurrence+of+nasal+inverted+papilloma. assertion.
- assertion asSentence X+protein+of+hepatitis+B+virus+%28HBx%29+overcomes+cellular+senescence+provoked+by+a+universal+premature+senescence+inducer%2C+H%282%29O%282%29%2C+in+human+hepatoma+cells+by+repressing+p16%28INK4a%29+expression+via+DNA+methylation. assertion.
- assertion asSentence Down-regulation+of+p16INK4A+mRNA+is+associated+with+acute+myeloid+leukemia+at+older+age. assertion.
- assertion asSentence Down-regulation+of+p16INK4A+is+associated+with+severity+of+cervical+lesions. assertion.
- assertion asSentence C.-21C+%3E+T+CDKN2A+variant+is+a+melanoma-predisposing+mutation. assertion.
- assertion asSentence Loss+of+p16+is+associated+with+lung+cancer. assertion.
- assertion asSentence Epigenetic+repression+of+p16%28INK4A%29+by+latent+Epstein-Barr+virus+requires+the+interaction+of+EBNA3A+and+EBNA3C+with+CtBP. assertion.
- assertion asSentence The+detected+opposite+effects+of+p16%28INK4a%29+at+the+levels+of+growth-regulatory+galectins-1+and+-3+shift+the+status+markedly+towards+the+galectin-1-dependent+pro-anoikis+activity. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+in+CDKN2A+is+associated+with+Philadelphia+positive+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence TP53+mutation+and+CDKN2A+methylation+specifically+interact+to+promote+lung+tumorigenesis+in+subjects+with+CYP1A1+risk+genotype. assertion.
- assertion asSentence Activation+of+the+Cyclin+D1+promoter+by+ErbB3+is+regulated+by+p14ARF. assertion.
- assertion asSentence p16+Expression+in+conjunctival+melanocytic+lesions+to+be+a+good+marker+to+differentiate+nevi+and+primary+acquired+melanoses+from+melanomas. assertion.
- assertion asSentence The+promoter+methylation+and+mutation+of+p16+gene+is+associated+with+ovarian+cancer. assertion.
- assertion asSentence p16+promoter+hypermethylation+and+intake+of+local+hot+salted+tea+and+sun-dried+foods+are+associated+with+gastric+tumors. assertion.
- assertion asSentence High+expression+of+p16%28INK4a%29+and+low+expression+of+Bmi1+are+associated+with+endothelial+cellular+senescence+in+human+cornea. assertion.
- assertion asSentence The+increased+p16%28INK4a%29+immunopositivity+is+associated+with+high-grade+squamous+intraepithelial+lesions+and+invasive+squamous+cell+carcinomas+in+cervical+malignancies. assertion.
- assertion asSentence Inactivation+of+tumor+suppressor+genes+p15%28INK4b%29+and+p16%28INK4a%29+in+primary+cutaneous+B+cell+lymphoma. assertion.
- assertion asSentence Variations+confer+impaired+glucose-+and+tolbutamide-induced+insulin+release+in+middle-aged+and+young+healthy+subjects. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+CDKN2B+is+associated+with+type+2+diabetes. assertion.
- assertion asSentence CDKN2A+CDKN2B+and+ANRIL+is+the+susceptibility+locus+for+coronary+heart+disease+%28CHD%29+and+periodontitis. assertion.
- assertion asSentence Genetic+variation+at+the+CDKN2A%2FCDKN2B+locus+predicts+stroke+in+hypertensive+patients. assertion.
- assertion asSentence The+comparable+frequency+of+methylation+of+p15INK4b+and+p16INK4a+underscores+the+widespread+importance+of+the+mechanism+of+p15INK4b+and%2For+p16INK4a+inactivation+in+the+development+of+oral+carcinomas. assertion.
- assertion asSentence The+human+p19%28INK4d%29+gene+is+under+the+control+of+TATA-less+promoter+and+the+Sp1+binding+site+is+involved+in+the+transcription. assertion.
- assertion asSentence CDK2+and+PKA+mediated-sequential+phosphorylation+is+critical+for+p19INK4d+function+in+the+DNA+damage+response+to+ensure+cell+survival. assertion.
- assertion asSentence Lack+of+corneodesmosin+causes+an+epidermal+barrier+defect+supposed+to+account+for+the+predisposition+to+atopic+diseases. assertion.
- assertion asSentence CDSN+plays+a+vital+role+in+the+structural+and+functional+integrity+of+the+epidermis+and+the+hair+follicle+integrity+by+preventing+the+rupture+of+corneodesmosome. assertion.
- assertion asSentence A+sensitive+and+specific+marker+for+differentiating+metastatic+colorectal+adenocarcinoma+from+mucinous+bronchioloalveolar+adenocarcinoma. assertion.
- assertion asSentence Phosphorylation+of+CDX2+mediates+its+ubiquitin-dependent+proteasome+degradation. assertion.
- assertion asSentence The+abnormal+expression+of+CDX%282%29+and+E-cadherin+plays+an+important+role+in+the+development+of+gastric+carcinoma. assertion.
- assertion asSentence The+Cdx2+protein+is+expressed+frequently+in+endometrial+lesions+with+squamous+differentiation. assertion.
- assertion asSentence Frequency+and+pattern+of+CDX2+staining+in+the+more+common+histologic+subtypes+of+cervical+adenocarcinoma+is+parallel+to+that+which+is+seen+for+adenocarcinomas+of+the+upper+gastrointestinal+tract+and+pancreaticobiliary+system. assertion.
- assertion asSentence The+inhibitory+effect+of+ERK1%2F2+upon+Cdx2+in+colorectal+cancer+cells+is+in+sharp+contrast+to+its+stimulatory+effect+upon+Cdx2+expression+in+trophectoderm+and+trophoblast+stem+cells. assertion.
- assertion asSentence Low+CDX2+expression+is+associated+with+gallbladder+adenocarcinoma. assertion.
- assertion asSentence BMP4+activation+in+non-specialized+columnar+metaplasia+and+early+expression+of+CDX2+are+involved+in+the+columnar+epithelial+differentiation+of+Barrett%27s+esophagus. assertion.
- assertion asSentence Alpha-methylacyl-coenzyme+A+racemase+expression+is+associated+with+mucin+phenotypes+of+gastric+neoplasia%2C+particularly+with+the+expression+of+CDX2+and+MUC5AC. assertion.
- assertion asSentence Ras+signaling+enhances+the+activity+of+C%2FEBP+alpha+to+induce+granulocytic+differentiation+by+phosphorylation+of+serine+248. assertion.
- assertion asSentence Expression+of+mutated+CEBPA+in+human+CD34%2B+cord+blood+cells+dramatically+inhibited+differentiation+of+both+myeloid+and+erythroid+lineages. assertion.
- assertion asSentence CEBPA+is+a+DNA+damage-inducible+p53-regulated+mediator+of+the+G1+checkpoint+in+keratinocytes. assertion.
- assertion asSentence CEBPA+is+activated+by+juxtaposition+to+the+immunoglobulin+gene+enhancer+upon+its+rearrangement+with+the+immunoglobulin+heavy-chain+locus+in+precursor+B-cell+acute+lymphoblastic+leukemia+harboring+t%2814%3B19%29%28q32%3Bq13%29. assertion.
- assertion asSentence CEBPA+mutations+are+associated+with+acute+myelogenous+leukemia. assertion.
- assertion asSentence AP2alpha+suppresses+C%2FEBPalpha+promoter+activity+and+protein+expression+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence Down-regulation+of+CEBPA+activity+contributes+to+MN1-modulated+proliferation+and+impaired+myeloid+differentiation+of+hematopoietic+cells. assertion.
- assertion asSentence In+myocardial+samples+from+patients+with+heart+failure%2C+quantitative+real-time+polymerase+chain+reaction+reveals+an+increase+in+messenger+RNA+for+C%2FEBP+homologous+protein+%28CHOP%29. assertion.
- assertion asSentence Methylation+of+TET2%2C+CBL+and+CEBPA+is+infrequent+in+myeloproliferative+neoplasms+at+diagnosis. assertion.
- assertion asSentence CEBPA+methylation+status+is+a+useful+prognostic+biomarker+for+acute+myeloid+leukemia+%28AML%29+patients. assertion.
- assertion asSentence Both+higher+MPO+expression+and+the+CEBPA+%28double-mut%29+genotype+appeared+to+be+associated+with+improved+overall+survival+after+intensive+chemotherapy. assertion.
- assertion asSentence The+mechanisms+for+galectin-1+expression+regulation+and+HIF-1alpha-+and+C%2FEBPalpha-induced+leukemic+cell+differentiation. assertion.
- assertion asSentence C%2FEBP+beta+is+an+essential+signaling+component+for+inhibition+of+NF-kappa+B-mediated+transcription+in+TNF-tolerant+monocytic+cells. assertion.
- assertion asSentence IL-17+is+a+potent+inducer+of+CRP+expression+via+p38+MAPK+and+ERK1%2F2-dependent+NF-kappaB+and+C%2FEBPbeta+activation. assertion.
- assertion asSentence PPARgamma+agonists+have+diverging+and+overlapping+mechanisms+blocking+transactivation+of+transcription+factors+NF-kappaB+and+C%2FEBPbeta. assertion.
- assertion asSentence Pyk2+is+induced+and+involved+in+monocyte+differentiation+and+C%2FEBPbeta+is+a+critical+regulator+of+the+Pyk2+expression. assertion.
- assertion asSentence Two+CCAAT%2Fenhancer-binding+protein+%28C%2FEBP%29+family+members+%5BC%2FEBP-homologous+protein+%28CHOP%29+and+C%2FEBPbeta%5D+enhanced+V2+transcription+via+different+pathways. assertion.
- assertion asSentence C%2FEBPbeta+is+a+mediator+of+the+deleterious+effects+of+unsaturated+free+fatty+acids+on+beta-cell+function. assertion.
- assertion asSentence Ha-Ras+transformation+of+MCF10A+cells+leads+to+repression+of+Singleminded-2s+through+NOTCH+and+C%2FEBPbeta. assertion.
- assertion asSentence Down+regulation+of+CEBPB+is+associated+with+cervical+squamous+cell+carcinoma. assertion.
- assertion asSentence CCAAT%2FEnhancer-binding+protein+%7Bbeta%7D+and+NF-%7Bkappa%7DB+mediate+high+level+expression+of+chemokine+genes+CCL3+and+CCL4+by+human+chondrocytes+in+response+to+IL-1%7Bbeta%7D. assertion.
- assertion asSentence Mutation+of+the+C%2FEBP-beta+response+element+abrogates+C%2FEBP-beta-+and+glucocorticoid+receptor-mediated+transactivation+of+norepinephrine+transporter. assertion.
- assertion asSentence The+ERK_CEBP%2Fbeta+intracellular+signaling+is+a+key+inflammatory+pathway+that+links+phagocytosis+of+wear+particles+to+inflammatory+gene+expression+in+osteoprogenitors. assertion.
- assertion asSentence C%2FEBPdelta+ubiquitination+is+not+required+for+proteasome-mediated+C%2FEBPdelta+degradation+and+the+presence+of+ubiquitin+does+not+increase+C%2FEBPdelta+degradation+by+the+proteasome. assertion.
- assertion asSentence Retinoic+acid+signaling+in+granulocytic+differentiation+involves+regulated+expression+of+CHOP+protein+and+C%2FEBPepsilon+in+a+coordinated+fashion. assertion.
- assertion asSentence Substantial+quantitities+of+C-EBPepsilon+are+expressed+in+human+neutrophils%2C+especially+the+p14+and+p32+variants. assertion.
- assertion asSentence Binds+DC-SIGN+and+inhibits+transfer+of+HIV-1+to+CD4%2B+T+lymphocytes. assertion.
- assertion asSentence CENP-H-containing+complex+facilitates+deposition+of+newly+synthesized+CENP-A+into+centromeric+chromatin+in+cooperation+with+FACT+and+CHD1. assertion.
- assertion asSentence UNG2+colocalizes+with+CENP-A+and+H2AX+phosphorylation+at+centromeres+in+normally+cycling+cells. assertion.
- assertion asSentence Anti-CENP-B+autoantibodies+in+breast+cancer+patients+prolong+disease-free+and+overall+survival. assertion.
- assertion asSentence DNMT3B+interacts+with+CENP-C+to+modulate+DNA+methylation+and+the+histone+code+at+centromere. assertion.
- assertion asSentence Depletion+of+CENP-E+leads+to+chromosomes+missegregation+and+cell+death+during+mitotic+delay. assertion.
- assertion asSentence The+unusually+slow+CENP-E+microtubule+association+step+favors+CENP-E+binding+of+stable+microtubules+over+dynamic+ones%2C+a+mechanism+that+would+bias+CENP-E+binding+to+kinetochore+fibers. assertion.
- assertion asSentence Rab5+forms+a+complex+with+a+subset+of+CENP-F+in+mitotic+cells+and+regulates+the+kinetics+of+release+of+CENP-F+from+the+nuclear+envelope+and+its+accumulation+on+kinetochores. assertion.
- assertion asSentence The+high-resolution+proteomic+approach+demonstrates+that+hCE1+is+a+good+candidate+for+further+validation+as+a+serologic+glycoprotein+biomarker+for+HCC. assertion.
- assertion asSentence The+solution+structure+of+the+long+C-terminal+fragment+of+centrin+2+exhibits+an+open+two+EF-hand+structure%2C+similar+to+the+conformation+of+related+Ca%282%2B%29-saturated+regulatory+domains. assertion.
- assertion asSentence Oxidative+radicals+induce+high+proportions+of+irreversible+damages+%28polymerisation%29+centrin+2+is+highly+sensitive+to+ionising+radiation. assertion.
- assertion asSentence Mps1-dependent+phosphorylation+of+Cetn2+stimulates+the+canonical+centriole+assembly+pathway. assertion.
- assertion asSentence CDC25B+forms+a+close+association+with+Ctn-2+proteins+at+the+centrosome. assertion.
- assertion asSentence In+men+with+coronary+heart+disease+%28CHD%29+and+high+density+lipoprotein+cholesterol+%28HDL-C%29deficiency%2C+the+CETP+TaqI+B2B2+genotype+is+significantly+reduced+and+is+associated+with+higher+levels+of+plasma+HDL-C+and+lower+CHD+risk. assertion.
- assertion asSentence Role+of+CETP+in+modulating+HDL-C+and+cardiovascular+disease. assertion.
- assertion asSentence CETP+genotypes+have+effects+on+the+serum+lipid+profile+among+renal+transplant+patients. assertion.
- assertion asSentence Role+for+CETP+in+remodeling+HDL+and+providing+an+alternative+pathway+for+the+selective+uptake+of+HDL+cholesteryl+ester+by+the+liver. assertion.
- assertion asSentence %28Cholesteryl+ester+transfer+protein%29+CETP+expression+restores+to+normal+the+impaired+reverse+cholesterol+transport+in+mice+deficient+in+scavenger+receptor+class+B%2C+type+I. assertion.
- assertion asSentence Interaction+between+the+CETP+TaqIB+polymorphism+and+intake+of+dietary+fat+on+plasma+HDL+concentration. assertion.
- assertion asSentence Niacin+increases+HDL+by+reducing+hepatic+expression+and+plasma+levels+of+cholesteryl+ester+transfer+protein+in+APOE%2A3Leiden.CETP+mice. assertion.
- assertion asSentence TaqIB+abd+I405V+polymorphisms+of+CETP+are+moderately+associated+with+obesity+risk+in+chinese+population. assertion.
- assertion asSentence The+CETP-induced+increase+of+triglycerides+%28TG%29+in+the+HDL+fraction+of+E3L+mice+is+not+associated+with+changes+in+the+production+of+TG+or+with+tissue-specific+clearance+of+TG+from+the+plasma. assertion.
- assertion asSentence Cholesteryl+ester+transfer+protein+polymorphism+%28TaqIB%29+associates+with+risk+in+postinfarction+patients+with+high+C-reactive+protein+and+high-density+lipoprotein+cholesterol+levels. assertion.
- assertion asSentence CETP+inhibition+specifically+improves+postprandial+SR-BI+and+ABCG1-dependent+efflux+to+larger+HDL2b+subspecies. assertion.
- assertion asSentence CETP+bridges+a+ternary+complex+with+its+N-terminal+beta-barrel+domain+penetrating+into+high-density+lipoproteins+and+its+C-terminal+domain+interacting+with+low-density+lipoprotein+or+very-low-density+lipoprotein. assertion.