Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Increases+the+susceptibility+of+macrophages+to+oxidized+low+density+lipoprotein-induced+apoptosis. assertion.
- assertion asSentence Cannabinoid+receptor+type+1-+and+2-mediated+increase+in+cyclic+AMP+inhibits+T+cell+receptor-triggered+signaling. assertion.
- assertion asSentence Cyanidin+and+delphinidin+are+ligands+with+moderate+affinity+to+human+CB2+and+CB1. assertion.
- assertion asSentence CNR2+functional+variant+%28Q63R%29+influences+childhood+immune+thrombocytopenic+purpura. assertion.
- assertion asSentence The+relative+treatment+benefit+of+iloperidone+compared+with+placebo+in+patients+with+schizophrenia+is+enhanced+in+patients+homozygous+G%2FG+for+the+rs1800169+polymorphism+of+CNTF. assertion.
- assertion asSentence PTP-1B+constitutes+a+key+divergent+element+between+leptin%2Finsulin+and+CNTF+signaling+pathways+at+the+neuronal+level. assertion.
- assertion asSentence The+CNTF+1357+G+--%3E+A+polymorphism+explains+only+a+small+portion+of+the+variability+in+the+muscle+strength+response+to+training+in+women. assertion.
- assertion asSentence F3+acts+as+a+functional+ligand+for+Notch+during+oligodendrocyte+maturation. assertion.
- assertion asSentence In+the+presence+of+high+molecular+weight+fragments+of+type+I+collagen%2C+type+I+procollagen+synthesis+is+inhibited. assertion.
- assertion asSentence A+degradation+fragment+originating+from+the+helical+part+of+type+I+collagen+consisting+of+residues+620-633+of+the+alpha+1+chain+sequence+is+useful+clinically+as+a+bone+resorption+marker+in+patients+with+osteoporosis. assertion.
- assertion asSentence COL1A1+gene+expression+is+downregulated+by+B-Myb+in+fibroblasts+from+patients+with+systemic+sclerosis. assertion.
- assertion asSentence The+lower+collagen+content+in+the+endopelvic+fascia+and+skin+of+women+with+SUI+is+not+due+to+reduced+collagen+synthesis+or+selective+reduction+in+synthesis+of+either+collagen+I+or+collagen+III. assertion.
- assertion asSentence The+G-T+polymorphism+at+the+Sp+1+binding+site+of+the+gene+encoding+alpha-1+chain+of+type+1+collagen+is+associated+with+increased+risk+of+stress+urinary+incontinence+in+women. assertion.
- assertion asSentence The+between-dose+recovery+of+serum+C-telopeptide+of+type+I+collagen+does+not+negatively+affect+the+efficacy+of+once-monthly+ibandronate. assertion.
- assertion asSentence Over+one+fourth+of+women+with+cervical+insufficiency+have+a+family+history+of+cervical+insufficiency+and+the+COL1A1+intron+1SP1+and+TGFbeta+Arg-25-Pro+polymorphisms+are+associated+with+the+condition. assertion.
- assertion asSentence Chondroitin+sulphate+and+its+derived+hydrolytic+fragments+%28CSf%29+repress+COL1A1+gene+transcription+through+a+-112%2F-61+bp+sequence+upstream+the+start+site+of+transcription+and+imply+hc-Krox+and+Sp1+transcription+factors. assertion.
- assertion asSentence Type+I+collagen+provides+a+template+of+charged+amino+acid+residues+that+dictates+ion+binding+critical+to+subsequent+nucleation+events+for+mineral+formation+in+vertebrate+tissues. assertion.
- assertion asSentence Missense+mutation+in+COL1A1+is+associated+with+infantile+cortical+hyperostosis. assertion.
- assertion asSentence The+catalytic+domain+of+MMP-12+binds+to+the+triple+helix+and+cleaves+the+typical+sites+-Gly%28775%29-Leu%28776%29-+in+alpha-2+type+I+collagen+and+-Gly%28775%29-Ile%28776%29-+in+alpha-1+type+I+and+type+III+collagens+and+at+multiple+other+sites+in+both+collagen+types. assertion.
- assertion asSentence Elevated+C-terminal+type+I+collagen+telopeptide+is+associated+with+with+bone+metastases+from+castration-resistant+prostate+cancer. assertion.
- assertion asSentence The+patient+with+COL1A1+Asp1219Asn+mutation+has+mild+osteogenesis+imperfecta. assertion.
- assertion asSentence From+second+harmonic+generation+microscopy+polarization+in%2C+polarization+out+%28PIPO%29+measurements+of+type+I+collagen+in+human+lung+tissue%2C+a+theoretical+method+is+used+to+extract+the+triple-helix+orientation+angle+with+respect+to+the+collagen+fiber. assertion.
- assertion asSentence DNA+hypermethylation+near+the+transcription+start+site+of+collagen+alpha2%28I%29+gene+occurs+in+both+cancer+cell+lines+and+primary+colorectal+cancers. assertion.
- assertion asSentence Protein+kinase+C-delta+is+involved+in+the+regulation+of+the+alpha2%28I%29+collagen+gene+in+dermal+fibroblasts. assertion.
- assertion asSentence The+catalytic+domain+of+MMP-12+binds+to+the+triple+helix+and+cleaves+the+typical+sites+-Gly%28775%29-Leu%28776%29-+in+alpha-2+type+I+collagen+and+-Gly%28775%29-Ile%28776%29-+in+alpha-1+type+I+and+type+III+collagens+and+at+multiple+other+sites+in+both+collagen+types. assertion.
- assertion asSentence The+presence+of+type+II+collagen+in+the+extracellular+tumor+matrix+significantly+facilitates+the+diagnosis+of+mesenchymal+chondrosarcomas+in+the+absence+of+histologically+visible+chondroid+matrix+formation. assertion.
- assertion asSentence Trypsin+degrades+COL2A1+and+is+expressed+and+activated+in+mesenchymally+transformed+rheumatoid+arthritis+synovitis+tissue. assertion.
- assertion asSentence COL2A1+mutations+associated+with+marked+metaphyseal+dysplasia+with+only+mild+epiphyseal+and+spondylar+changes. assertion.
- assertion asSentence Association+of+a+p.Pro786Leu+variant+in+COL2A1+with+mild+spondyloepiphyseal+dysplasia+congenita+in+a+three-generation+family. assertion.
- assertion asSentence The+lower+collagen+content+in+the+endopelvic+fascia+and+skin+of+women+with+SUI+is+not+due+to+reduced+collagen+synthesis+or+selective+reduction+in+synthesis+of+either+collagen+I+or+collagen+III. assertion.
- assertion asSentence Antisense+oligodeoxynuclotides+down-regulate+collagen+type+III+gene+expression. assertion.
- assertion asSentence High+glucose+levels+downregulate+mRNA+levels+in+dermal+fibroblast+cell+cultures. assertion.
- assertion asSentence COL3A1+is+a+disease-associated+gene+in+both+paediatric+and+adult+gastroesophageal+reflux+and+COL3A1+is+genetically+associated+with+hiatal+hernia+in+adult+males. assertion.
- assertion asSentence Type+IV+collagen+expression+changed+in+candidal+leukoplakia+with+epithelial+dysplasia. assertion.
- assertion asSentence Modulation+of+triple-helical+stability+and+subsequent+melanoma+cellular+responses+by+single-site+substitution+of+fluoroproline+derivatives+of+collagen+alpha1%28IV%29. assertion.
- assertion asSentence p53+directly+activated+transcription+of+the+COL4A1+gene+by+binding+to+an+enhancer+region+m+of+its+3%27+end. assertion.
- assertion asSentence Mutation+does+not+represent+a+further+major+genetic+locus+for+thin+basement+membrane+nephropathy. assertion.
- assertion asSentence Persistent+familial+hematuria+in+children+often+occurs+at+the+COLA4A+locus+for+thin+membrane+nephropathy. assertion.
- assertion asSentence Type+IV+collagen+alpha6+chain-derived+noncollagenous+domain+1+%28alpha6NC1%29+is+an+endogenous+inhibitor+of+angiogenesis+and+tumor+growth. assertion.
- assertion asSentence Variants+within+the+MMP3+gene+are+associated+with+Achilles+tendinopathy+and+the+MMP3+gene+variant+rs679620+and+the+COL5A1+marker+rs12722+interact+to+modify+the+risk+of+tendinopathy. assertion.
- assertion asSentence Tendinopathic+phenotype+is+associated+with+increased+COL5A1+mRNA+stability. assertion.
- assertion asSentence Col6A3+fusion+with+colony-stimulating+factor-1+gene+is+associated+with+tenosynovial+giant+cell+tumors. assertion.
- assertion asSentence Recessive+dystrophic+epidermolysis+bullosa-I+is+associated+with+specific+recessive+arginine+and+glycine+substitutions+in+the+triple+helix+domain+of+type+VII+collagen. assertion.
- assertion asSentence Mutations+in+the+coding+sequence+of+the+human+collagen+XVII+%28COL17A1%29+gene+are+not+the+cause+of+Thiel-Behnke+Corneal+Dystrophy. assertion.
- assertion asSentence Truncation+of+the+intracellular+domain+of+BP180+impairs+the+organization+of+hemidesmosomes%2C+affecting+both+the+mechanical+stability+of+basal+keratinocytes+and+dermoepidermal+cohesion. assertion.
- assertion asSentence IgE+autoantibodies+to+BP180+and+BP230+are+detected+at+high+frequencies+in+bullous+pemphigoid. assertion.
- assertion asSentence Collagen+XVII+has+a+function+in+the+attachment+of+podocyte+foot+processes+to+the+glomerular+basement+membrane. assertion.
- assertion asSentence Matrix-matrix+interaction+of+cartilage+oligomeric+matrix+protein+and+fibronectin. assertion.
- assertion asSentence COMP%2C+CXCL9+and+KRT19+play+an+important+role+in+the+pathopoiesis+of+oral+submucosal+fibrosis. assertion.
- assertion asSentence There+is+an+association+between+Val108%2F158+Met+polymorphism+of+the+COMT+gene+in+schizophrenia. assertion.
- assertion asSentence Effect+of+catechol-O-methyltransferase+val158met+genotype+on+attentional+control. assertion.
- assertion asSentence In+normal+subjects%2C+there+is+a+functional+Val158Met+and+a+single-nucleotide+polymorphism+which+predicts+inefficient+prefrontal+working+memory+response. assertion.
- assertion asSentence The+effects+of+COMT+on+the+release+of+adrenocorticotrophin+hormone+depend+on+the+presence+of+the+low-expression+MAOA+variant+in+the+same+individual. assertion.
- assertion asSentence Relationship+between+the+DRD4+and+COMT+genes+and+different+aspects+of+executive+functions+and+the+absence+of+such+a+relationship+in+relation+to+verbal+memory. assertion.
- assertion asSentence In+working+memory%2C+COMT+genotype+can+be+used+as+a+genetic+marker+for+differential+dopaminergic+modulation+of+neural+circuitry. assertion.
- assertion asSentence There+is+a+highly+significant+association+between+a+haplotype+of+two+functional+SNPs+and+aggressive+behavior+in+schizophrenia. assertion.
- assertion asSentence The+catechol-O-methyltransferase+Val%28108%2F158%29Met+polymorphism+affects+antidepressant+response+to+paroxetine+in+a+naturalistic+setting. assertion.
- assertion asSentence The+COMT%28Val158Met%29+polymorphism+genotype+effect+on+cortical+morphology+in+a+right+prefrontal+cortical+region+intimately+linked+to+key+aspects+of+cognition. assertion.
- assertion asSentence The+COMTval%28158%29met+polymorphism+modulates+both+the+activity+and+functional+connectivity+of+brain+regions+within+working+memory+networks. assertion.
- assertion asSentence A+gene+primarily+controlling+prefrontal+dopamine+function+%28COMT%29+is+associated+with+a+particular+type+of+directed+exploration. assertion.
- assertion asSentence COMT+val%28158%29met+genotype+not+association+with+smooth+pursuit+eye+movements+in+schizophrenia. assertion.
- assertion asSentence Default+network+connectivity+that+involves+the+prefrontal+cortex+is+modulated+by+COMT+val%28158%29met+through+differential+effects+on+prefrontal+dopamine+levels. assertion.
- assertion asSentence Polymorphisms+in+catechol-O-methyltransferase+predispose+towards+Madurella+mycetomatis-induced+mycetoma+susceptibility. assertion.
- assertion asSentence Carriers+of+the+high+activity+COMT+variant+are+more+prone+to+develop+a+higher+level+of+nicotine+dependence%2C+or+that+they+release+more+dopamine+than+carriers+of+Met%2FMet+or+Met%2FVal+genotypes. assertion.
- assertion asSentence COMT+associates+with+differences+in+cortisol+secretion+during+adolescence. assertion.
- assertion asSentence The+COMT+functional+polymorphism+rs4680+contributes+to+schizophrenia+genetic+susceptibility. assertion.
- assertion asSentence Single+nucleotide+polymorphism%2C+Valine-methionine+polymorphism+is+signifantly+associated+with+reduced+size+of+the+corpus+callosum+in+adolescents+and+young+adults. assertion.
- assertion asSentence Combined+catechol-O-methyltransferase+and+mu-opioid+receptor+gene+polymorphisms+affect+morphine+postoperative+analgesia+and+central+side+effects. assertion.
- assertion asSentence The+COMT+Val158Met+polymorphism+is+significantly+associated+with+panic+disorder+%28PD%29+in+a+Turkish+population+of+PD+patients. assertion.
- assertion asSentence COMT+val158met+polymorphism+is+associated+neural+pain+processing. assertion.
- assertion asSentence Catechol-O-methyltransferase+%28COMT%29+metabolizes+dopamine. assertion.
- assertion asSentence Mutations+of+the+KLF6+gene+play+a+role+in+the+pathogenesis+of+astrocytic+gliomas. assertion.
- assertion asSentence KLF6-mediated+changes+in+E-cadherin+levels+are+accompanied+by+downstream+changes+in+both+the+subcellular+localization+of+beta-catenin+and+c-myc+expression+levels. assertion.
- assertion asSentence The+isoform+of+KLF6+protein+antagonizes+the+ability+of+wild-type+KLF6+to+suppress+cell+proliferation+and+induce+cellular+differentiation+in+HepG2+cells. assertion.
- assertion asSentence KLF6+nuclear+export+to+be+Crm1-dependent. assertion.
- assertion asSentence Low+KLF6+is+associated+with+acute+myeloid+leukemia. assertion.
- assertion asSentence Internalization+of+endogenous+human+Ctr1+in+response+to+elevated+extracellular+copper+levels+does+not+play+a+significant+regulatory+role+in+copper+homeostasis. assertion.
- assertion asSentence A+lower+expression+of+CST+exists+in+diabetic+retinas+and+it+is+associated+with+retinal+neurodegeneration. assertion.
- assertion asSentence MAP3K8+and+PRKCZ+cooperate+in+the+regulation+of+the+transcriptional+activity+of+NFATC2+through+the+phosphorylation+of+its+amino-terminal+domain. assertion.
- assertion asSentence Tensile+strain+and+magnetic+particle+force+application+do+not+induce+MAP3K8+and+IL-1B+differential+gene+expression+in+a+similar+manner+to+fluid+shear+stress+in+human+mesenchymal+stem+cells. assertion.
- assertion asSentence TPL2+kinase+plays+a+critical+role+in+the+promotion+of+androgen+depletion-independent+prostate+cancer+progression. assertion.
- assertion asSentence Cytochrome+c+oxidase+is+decreased+significantly+in+platelets+and+hippocampus+in+Alzheimer+patients+compared+to+controls. assertion.
- assertion asSentence In+vitro+equilibrium+unfolding+of+CP+involves+intermediates+and+the+copper+ions+are+removed+in+stages. assertion.
- assertion asSentence Progeny+of+families+with+a+positive+history+of+cardiovascular+diseases+and%2For+hyperlipidemia+have+atherogenic+lipid+profile+and+increased+ceruloplasmin+levels. assertion.
- assertion asSentence Protein+S+inhibits+TAFI+activation+in+two+ways. assertion.
- assertion asSentence Ala147Thr+and+C%2B1542G+polymorphisms+in+the+TAFI+gene+are+not+asssociated+with+a+higher+risk+of+venous+thrombosis+in+FV+Leiden+carriers. assertion.
- assertion asSentence The+GG+genotype+of+the+C1542G+polymorphism+of+TAFI+displays+risk+factors+for+the+manifestation+of+thrombotic+microangiopathies. assertion.
- assertion asSentence Thrombin+activatable+fibrinolysis+inhibitor+and+alpha%282%29-antiplasmin+are+not+markers+for+recanalization+in+patients+with+ischemic+stroke+treated+with+recombinant+tissue-type+plasminogen+activator. assertion.
- assertion asSentence No+effect+of+gestational+diabetes+on+plasma+thrombin-activatable+fibrinolysis+inhibitor+%28TAFI%29+antigen+levels. assertion.
- assertion asSentence Women+with+PCOS+have+impaired+fibrinolysis%2C+as+reflected+by+increased+TAFI. assertion.
- assertion asSentence Increased+TAFI+antigen+levels+and+impaired+fibrinolysis+are+pathogenetic+factors+in+preeclampsia%2C+regardless+of+whether+or+not+preeclampsia+is+associated+with+the+presence+of+antiphospholipid+antibodies. assertion.
- assertion asSentence Flexibility+of+the+thrombin-activatable+fibrinolysis+inhibitor+pro-domain+enables+productive+binding+of+protein+substrates. assertion.
- assertion asSentence CLDN4%2C+clustered+with+CLDN3+at+human+chromosome+7q11%2C+is+a+four-transmembrane+protein+with+WWCC+motif%2C+defined+by+W-X%2817-22%29-W-X%282%29-C-X%288-10%29-C. assertion.
- assertion asSentence Increased+claudin-4+expression+is+associated+with+breast+cancer. assertion.
- assertion asSentence The+expressions+of+PSCA+and+Claudin-4+are+upregulated+in+the+pancreatic+carcinomas. assertion.
- assertion asSentence Downregulation+of+claudin-4+correlates+with+gastric+cancer+aggressiveness. assertion.
- assertion asSentence CLDN3%2C+clustered+with+CLDN4+at+human+chromosome+7q11%2C+is+a+four-transmembrane+protein+with+WWCC+motif%2C+defined+by+W-X%2817-22%29-W-X%282%29-C-X%288-10%29-C. assertion.
- assertion asSentence Airway+tight+junctions+are+regulated+by+claudin+interactions+that+confer+the+selectivity+of+the+junction. assertion.
- assertion asSentence Reduced+claudin-7+expression+correlates+with+loss+of+differentiation+in+thyroid+neoplasms. assertion.
- assertion asSentence Claudin-3+and+claudin-7+expression+in+effusions+independently+predicts+poor+survival+in+ovarian+cancer. assertion.