Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Aspirin+induces+gastric+epithelial+barrier+dysfunction+by+activating+p38+MAPK+via+claudin-7. assertion.
- assertion asSentence Claudin-7+is+significantly+upregulated+in+epithelial+ovarian+cancer. assertion.
- assertion asSentence Deletion+of+the+fifth+exon+in+the+CPOX+gene+is+associated+with+hereditary+coproporphyria. assertion.
- assertion asSentence Enhanced+expression+of+coproporphyrinogen+oxidase+is+associated+with+malignant+brain+tumors. assertion.
- assertion asSentence Impaired+fasting+tolerance+among+Alaska+native+children+with+a+common+carnitine+palmitoyltransferase+1A+sequence+variant. assertion.
- assertion asSentence Transcriptional+activation+of+the+CPT1B+promotor+by+peroxisome+proliferator-activated+receptors-alpha+and+myocyte-specific+enhancer-binding-factor+2C. assertion.
- assertion asSentence Complement+receptors+type+1+%28CR1%2C+CD35%29+and+2+%28CR2%2C+CD21%29+cooperate+in+the+binding+of+hydrolyzed+complement+factor+3+%28C3i%29+to+human+B+lymphocytes. assertion.
- assertion asSentence CR1+variants+are+not+associated+with+sporadic+Alzheimer%27s+disease+in+a+population+of+Chinese+patients. assertion.
- assertion asSentence Both+CBF1+and+C%2FEBP-beta+bind+the+CR2+promoter+in+B+cells+raising+the+possibility+that+these+factors+facilitate+or+respond+to+alterations+in+chromatin+structure+to+control+the+timing+and%2For+level+of+CR2+transcription. assertion.
- assertion asSentence Binding+between+Epstein+Barr+virus-transformed+B+cell+line-derived+exosomes+and+viral+structural+protein+gp350+is+dependent+on+CD21+expressed+on+the+B+cells. assertion.
- assertion asSentence Low+CRABP2+is+associated+with+pancreatic+ductal+adenocarcinoma. assertion.
- assertion asSentence Hypermethylation+in+the+CpG+island+of+the+CRABP2+gene+is+associated+with+astrocytic+gliomas. assertion.
- assertion asSentence hGRP-R+activation+stimulated+sustained+cyclic+AMP+response+element+binding+protein+%28CREB%29+phosphorylation+and+transactivation+in+duodenal+cancer+cells+through+a+protein+kinase+C+and+partially+p38+mitogen-activated+protein+kinase-dependent+pathway. assertion.
- assertion asSentence Activation+of+BTK+and+the+subsequent+phosphorylation+of+CREB+at+Ser-133+are+important+in+the+neuronal+differentiation+of+hippocampal+progenitor+cells. assertion.
- assertion asSentence CREB+is+activated+by+TNF%2FTNFR1+signaling+through+a+p38MAPK%2FMSK1+signaling+pathway. assertion.
- assertion asSentence CRH+plays+pathogenic+role+in+modulating+inflammatory+joint+disease+with+CREB%2FATF+family+of+transcription+factors+as+principal+effector+molecules+of+proinflammatory+mediator+action+in+rheumatoid+arthritis. assertion.
- assertion asSentence BDNF-+and+seizure-dependent+phosphorylation+of+STAT3+cause+the+adenosine+3%27%2C5%27-monophosphate+%28cAMP%29+response+element-binding+protein+%28CREB%29+family+member+ICER+%28inducible+cAMP+early+repressor%29+to+bind+with+phosphorylated+CREB+at+the+Gabra1%3ACRE+site. assertion.
- assertion asSentence Targeting+CREB+or+NF-kappaB+using+small-molecule+inhibitors%2C+such+as+KG-501%2C+holds+promise+as+a+preventive+and%2For+therapeutic+approach+for+NSCLC. assertion.
- assertion asSentence Isoflurane+inhibits+cyclic+adenosine+monophosphate+response+element-binding+protein+phosphorylation+and+calmodulin+translocation+to+the+nucleus+of+SH-SY5Y+cells. assertion.
- assertion asSentence The+anti-angiogenic+effect+of+PPARgamma+agonists+is+due%2C+at+least+in+part%2C+to+an+interference+with+the+VEGF-stimulated+PKCalpha-mediated+activation+of+CREB+and+the+related+expression+of+COX-2. assertion.
- assertion asSentence DNA+sequence+variation+in+the+CREB1+locus+is+strongly+associated+with+DeltaHR50+and+explains+a+considerable+proportion+of+the+quantitative+trait+locus+variance. assertion.
- assertion asSentence Loss+of+AP-2alpha+expression+in+metastatic+melanoma+occurs+via+a+dual+mechanism+involving+binding+of+CREB+to+the+AP-2alpha+promoter+and+CREB-induced+overexpression+of+another+oncogenic+transcription+factor%2C+E2F-1. assertion.
- assertion asSentence Cystic+fibrosis-related+CREB+regulation+is+mediated+directly+through+transgenic+beta-arrestin-2+expression+via+the+MEK-ERK+kinase+signaling+pathway. assertion.
- assertion asSentence The+phosphorylation+of+ATF-2+at+Ser-121+plays+a+key+role+in+the+c-Jun-mediated+activation+of+transcription+that+occurs+in+response+to+TPA. assertion.
- assertion asSentence Hyperosmotic+stress+can+activate+the+Plk3+signaling+pathway+that+subsequently+regulates+the+AP-1+complex+by+directly+phosphorylating+ATF-2+independent+from+the+effects+of+JNK+and+p38+activation. assertion.
- assertion asSentence Direct+involvement+of+CREB-binding+protein%2Fp300+in+sequence-specific+DNA+binding+of+virus-activated+interferon+regulatory+factor-3+holocomplex. assertion.
- assertion asSentence Regulatory+motifs+for+CREB-binding+protein+and+Nfe2l2+transcription+factors+in+the+upstream+enhancer+of+the+mitochondrial+uncoupling+protein+1+gene. assertion.
- assertion asSentence MUC5AC+gene+expression+are+mediated+by+a+complex+regulatory+cascade+controlling+interactions+between+CREB+and+c-Ets1+that+bind+to+a+promoter+element+in+the+MUC5AC+gene+enhancing+MUC5AC+gene+transcription. assertion.
- assertion asSentence PML+%28acute+promyelocytic+leukemia%29+nuclear+bodies+are+nuclear+sites+involved+in+the+ubiquitin-dependent+degradation+of+CBP. assertion.
- assertion asSentence CREBBP+variable+expression+%28family+1%29+and+somatic+mosaicism+%28family+2%29+contribute+to+the+phenotypic+variability+of+Rubinstein-Taybi+syndrome. assertion.
- assertion asSentence Selective+roles+for+cAMP+response+element-binding+protein+binding+protein+and+p300+protein+as+coregulators+for+androgen-regulated+gene+expression+in+advanced+prostate+cancer+cells. assertion.
- assertion asSentence Anscriptional+activation+of+the+cAMP-responsive+modulator+promoter+in+human+T+cells+is+regulated+by+protein+phosphatase+2A-mediated+dephosphorylation+of+SP-1+and+reflects+disease+activity+in+patients+with+systemic+lupus+erythematosus. assertion.
- assertion asSentence Corticotropin-releasing+hormone+inhibits+nuclear+factor-kappaB+binding+and+transcriptional+activity. assertion.
- assertion asSentence Expression+of+urocortin+mRNA+is+significantly+downregulated+in+the+Edinger-Westphal+nucleus+of+CRF-overexpressing+transgenic+mice+compared+with+wild-type. assertion.
- assertion asSentence CRH+plays+pathogenic+role+in+modulating+inflammatory+joint+disease+with+CREB%2FATF+family+of+transcription+factors+as+principal+effector+molecules+of+proinflammatory+mediator+action+in+rheumatoid+arthritis. assertion.
- assertion asSentence CRH+regulates+IL-18+production+through+the+MAPK+signaling+pathway+in+human+keratinocytes. assertion.
- assertion asSentence CSF+concentrations+of+the+stress+hormones+norepinephrine+and+CRH+differentially+change+after+exposure+to+1h+of+trauma-related+audiovisual+stimulation+in+chronic%2C+combat-related+PTSD. assertion.
- assertion asSentence The+relation+of+corticotropin+releasing+hormone+with+preterm+delivery+is+moderated+by+exposure+to+chronic+stressors+during+pregnancy. assertion.
- assertion asSentence Stress-induced+response+of+CRH+is+differentially+modulated+by+CRH+promoter+polymorphisms+in+rheumatoid+arthritis+patients. assertion.
- assertion asSentence Both+CRHR1+and+CRHR2+play+a+facilitatory+role+in+the+non-clathrin-%2C+non-caveolae-mediated+endocytosis+and+intracellular+signal+transduction+of+urocortin. assertion.
- assertion asSentence V1bR+and+CRHR1+can+form+constitutive+homo-+and+heterodimers. assertion.
- assertion asSentence Cultured+placental+trophoblasts+express+both+CRH-R1+and+CRH-R2. assertion.
- assertion asSentence CRF1+and+CRF2a+receptors+couple+to+different+G-proteins+in+stably+transfected+human+cells%2C+leading+to+transient+divalent+calcium+ion+mobilization+on+top+of+the+natural+increase+in+cyclic+AMP+stimulation. assertion.
- assertion asSentence CRH-R1+and+CRH-R2+receptors+and+their+endogenous+ligands+have+a+role+in+the+biology+of+human+endometrial+cancer. assertion.
- assertion asSentence Requirement+of+the+p130CAS-Crk+coupling+for+metastasis+suppressor+KAI1%2FCD82-mediated+inhibition+of+cell+migration+in+a+metastatic+prostate+cancer+cell+line. assertion.
- assertion asSentence Nck+and+Crk+mediate+distinct+VEGF-induced+signaling+pathways+that+serve+overlapping+functions+in+cell+migration. assertion.
- assertion asSentence CRMP1+and+EVC+genes+are+located+near+WFS1%2C+the+Wolfram+syndrome+type+1+gene. assertion.
- assertion asSentence ChIP+and+EMSA+demonstrated+that+p50+binds+to+a+kappaB+site+residing+between+-1753+and+-1743+of+the+CRMP-1+promoter+region. assertion.
- assertion asSentence Drp1+is+dephosphorylated+in+PINK1+deficient+cells+due+to+activation+of+the+calcium-dependent+phosphatase+calcineurin. assertion.
- assertion asSentence CRP+levels+increase+continuously+across+the+spectrum+of+fasting+glucose+in+both+sexes. assertion.
- assertion asSentence Significantly+higher+levels+in+patients+with+metabolic+syndrome+than+in+those+without. assertion.
- assertion asSentence Recombinant+and+natural+C-reactive+protein+have+opposite+effects+on+atherosclerosis+in+apolipoprotein+E-deficient+mice. assertion.
- assertion asSentence Homozygous+carriers+of+the+CRP+3%27+UTR+%2B1444C%3ET+polymorphism+do+not+have+a+significantly+increased+risk+of+spontaneous+venous+thromboembolism. assertion.
- assertion asSentence In+human+aortic+endothelial+cells%2C+CRP+upregulates+monocyte-endothelial+adhesion+by+activation+of+NF-kappaB+through+engaging+the+Fcgamma+receptors+CD32+and+CD64. assertion.
- assertion asSentence An+elevated+preoperative+C-reactive+protein+concentration+is+an+independent+predictor+of+poor+cancer-specific+survival+in+gastro-esophageal+cancers. assertion.
- assertion asSentence CRP+limits+excessive+complement+activation+on+targets+via+its+interactions+with+both+factor+H+and+C4b-binding+protein+%28C4BP%29. assertion.
- assertion asSentence C-reactive+protein+is+associated+with+leptin+and+interleukin+6+blood+levels+in+Japanese+type+2+diabetic+patients. assertion.
- assertion asSentence NT-proBNP+levels+correlate+with+PCT+and+CRP+levels+in+septic+patients. assertion.
- assertion asSentence Elevated+CRP+concentrations+in+early+pregnancy+are+associated+with+an+increased+risk+of+preterm+delivery. assertion.
- assertion asSentence Exploration+of+whether+inflammation+%28measured+by+plasma+C-reactive+protein+%28CRP%29+levels%29+is+related+to+insulin+resistance+and+to+parameters+of+metabolic+syndrome%2C+independent+of+obesity. assertion.
- assertion asSentence A+locus+on+chromosome+10+influences+C-reactive+protein+levels+in+two+independent+populations. assertion.
- assertion asSentence Levels+are+increased+in+young+women+with+polycystic+ovary+syndrome. assertion.
- assertion asSentence Serum+CRP+can+be+seen+as+a+novel%2C+widely+available+independent+prognostic+variable+of+ovarian+cancer. assertion.
- assertion asSentence Elevated+plasma+C-reactive+protein+is+associated+with+androgen-independent+prostate+cancer. assertion.
- assertion asSentence In+the+presence+of+PEt%2C+CRP+bound+to+native+low-density+lipoprotein+in+serum+also. assertion.
- assertion asSentence C-reactive+protein+%28CRP%29+elevation+in+patients+with+abdominal+aortic+aneurysm+is+independent+of+the+most+important+CRP+genetic+polymorphism. assertion.
- assertion asSentence In+the+nondiabetic+population%2C+smoking+associates+differently+with+subclinical+inflammation+between+genders%2C+with+a+decreased+adiponectin+level+in+women+and+with+an+increased+hs-CRP+level+in+men. assertion.
- assertion asSentence Higher+serum+high-sensitivity+CRP+levels+are+positively+associated+with+diabetes+mellitus+in+a+sample+of+US+non-Hispanic+blacks. assertion.
- assertion asSentence CRP+up-regulates+M-CSF+release+from+human+monocyte-derived+macrophages+and+human+aortic+endothelial+cells+and+increased+macrophage+proliferation. assertion.
- assertion asSentence High+C+reactive+protein+and+high+serum+fibrinogen+provide+prognostic+information+in+chronic+kidney+disease+patients. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+at+the+-390+position+of+the+CRP+gene+promoter+region+influence+CRP+basal+levels+in+such+a+way+that+the+%22C%22+allele+correlated+with+the+lowest+and+the+%22T%22+with+the+highest+after+kidney+transplantation. assertion.
- assertion asSentence Circulating+bacterial-derived+DNA+fragments+are+associated+with+higher+levels+of+C-reactive+protein+and+IL-6+in+hemodialysis+patients. assertion.
- assertion asSentence Periodontal+treatment+with+topical+antibiotics+improves+HbA1c+through+reduction+of+C+reactive+protein+in+type+2+diabetics. assertion.
- assertion asSentence Hs-CRP+level+positively+correlated+with+upper+gastrointestinal+lesions+severity. assertion.
- assertion asSentence Increased+serum+C-reactive+protein+concentration+is+associated+with+severe+chronic+periodontitis. assertion.
- assertion asSentence C-reactive-protein+levels+associated+with+infection+predict+short-+and+long-term+outcome+after+supratentorial+intracerebral+hemorrhage. assertion.
- assertion asSentence Tentative+cut+point+of+high-sensitivity+C-reactive+protein+for+a+component+of+metabolic+syndrome+in+Japanese. assertion.
- assertion asSentence Body+temperature+and+CRP+are+two+parameters+leading+to+comparable+information+in+more+than+80%25+of+infected+patients+receiving+specific+antibiotic+therapy. assertion.
- assertion asSentence CRP+and+the+risk+of+atherosclerotic+events. assertion.
- assertion asSentence CRP+genetic+polymorphism+is+associated+with+lymph+node+metastasis+in+thoracic+esophageal+squamous+cell+cancer. assertion.
- assertion asSentence CRP+have+a+protective+role+towards+the+clearance+of+damaged-erythrocytes+in+tuberculosis+and+visceral+leishmaniasis. assertion.
- assertion asSentence Dissociation+of+pentameric+to+monomeric+C-reactive+protein+on+activated+platelets+localizes+inflammation+to+atherosclerotic+plaques. assertion.
- assertion asSentence Leptin+stimulated+C-reactive+protein+production+by+human+coronary+artery+endothelial+cells. assertion.
- assertion asSentence Serum+levels+of+high-sensitivity+C-reactive+protein+and+procalcitonin+are+biomarkers+for+transplantrelated+complications+such+as+graft-versus-host+disease+or+infection. assertion.
- assertion asSentence C-Reactive+protein+is+a+valuable+predictive+marker+in+predialysis+chronic+kidney+disease. assertion.
- assertion asSentence Plasma+CRP+%28C-reactive+protein%29+is+associated+with+prevalent+MCI+%28mild+cognitive+impairment%29and+with+nonamnestic+MCI+in+elderly%2C+nondemented+persons+in+a+population-based+setting. assertion.
- assertion asSentence Higher+levels+of+CRP%2FBNP%2Ftroponin+T+are+strong%2C+independent+predictors+of+mortality+in+community+patients+with+heart+failure. assertion.
- assertion asSentence CRP+binding+is+enhanced+by+conformational+bending+at+the+neck+region+of+M-ficolin%2C+to+avoid+steric+hindrance+by+the+COL+domain. assertion.
- assertion asSentence The+average+MMP-9+and+CRP+concentrations+increased+with+increasing+degrees+of+relative+wall+stress+in+abdominal+aortic+aneurysms. assertion.
- assertion asSentence Hs-CRP+can+provide+additional+prognostic+information+for+the+risk+stratification+of+chronic+heart+failure+patients. assertion.
- assertion asSentence MMP-9+levels+are+associated+with+disease+severity+in+chronic+urticaria+patients+and+CRP+levels. assertion.
- assertion asSentence Impaired+kidney+function%2C+as+measured+by+cystatin+C%2C+has+an+independent+association+with+sudden+cardiac+death+risk+among+elderly+persons+without+clinical+cardiovascular+disease. assertion.
- assertion asSentence Elevated+preoperative+C-reactive+protein+is+associated+with+systemic+inflammatory+response+in+patients+undergoing+resection.+for+non-small+cell+lung+cancer. assertion.
- assertion asSentence The+presence+of+diabetes%2C+elevated+CRP+levels+and+reduced+glomerular+filtration+on+admission+is+associated+with+an+excessive+hospital+mortality+in+myocardial+infarction. assertion.
- assertion asSentence Elevated+C-reactive+protein+is+associated+with+metabolic+impairment+leading+to+cardiovascular+diseases. assertion.
- assertion asSentence C-reactive+protein+1846T%2FT+genotype+is+an+independent+predictor+of+a+poor+prognosis+in+patients+with+non-small+cell+lung+cancer. assertion.
- assertion asSentence Elevated+level+of+CRP+is+a+useful+parameter+in+the+severity+of+clinical+risk+of+pre-eclampsia+in+patients+with+BMI+%3C+25+kg%2Fm%282%29+at+third+trimester. assertion.
- assertion asSentence High+serum+C-reactive+protein+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence LPL+polymorphism+%28D9N%29+predicts+cardiovascular+disease+risk+directly+and+through+interaction+with+CETP+polymorphism+%28TaqIB%29+in+women+with+high+HDL+cholesterol+and+CRP. assertion.
- assertion asSentence High+C-reactive+protein+is+associated+with+Inflammation+and+thrombosis+in+essential+thrombocythemia+and+polycythemia+vera. assertion.