Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Progression+of+cutaneous+squamous+cell+carcinoma+in+immunosuppressed+patients+is+associated+with+reduced+CD123%2B+and+FOXP3%2B+cells+in+the+perineoplastic+inflammatory+infiltrate. assertion.
- assertion asSentence Vitamin+E+inhibits+IL-4+gene+expression+in+peripheral+blood+T+cells+by+blocking+binding+of+transcription+factors+to+two+important+IL-4+promoter+binding+sites+for+NF-kappaB+and+AP-1+and+interfering+with+promoter+activity+upon+T+cell+activation. assertion.
- assertion asSentence Number+of+CD8%2B%2FIL-4+cells+significantly+higher+in+young+than+in+elderly+untrained. assertion.
- assertion asSentence When+parasite+antigen-specific+IgE+is+present+in+a+filaria-infected+individual%2C+basophils+function+to+amplify+the+ongoing+Th2+immune+cell+response+by+releasing+IL-4+in+greater+amounts+and+more+frequently+than+CD4%2B+T+cells+in+response+to+filarial+antigen. assertion.
- assertion asSentence IL-4-producing+cells+inhibit+the+development+of+acute+graft+vs+host+disesase. assertion.
- assertion asSentence The+interaction+between+SNPs+in+IL-4%2FIL-13+pathway+significantly+influence+genetic+control+of+serum+IgE+levels+and+development+of+childhood+asthma. assertion.
- assertion asSentence This+is+the+first+demonstration+of+sex-specific+association+of+the+two+foremost+genes+of+the+IL-4+signalling+cascade+with+chronic+inflammatory+arthropathies. assertion.
- assertion asSentence NFKB%2C+IL4+and+IL5+expression+levels+are+elevated+in+T+cells+from+allergic+rhinitis+patients. assertion.
- assertion asSentence Polymorphism+in+the+promoter+of+the+IL-4+gene+is+associated+with+asthma+and+is+a+disease+modifier+in+terms+of+the+severity+of+AHR. assertion.
- assertion asSentence Proliferation+of+endometriotic+stromal+cells+induced+by+locally+produced+IL-4+is+involved+in+the+development+of+endometriosis. assertion.
- assertion asSentence The+concentrations+of+these+cytokines+%5Binterferon-gamma+%28IFN-gamma%29%2C+interleukin-4+%28IL-4%29+and+IL-10%5Dwere+significantly+higher+in+peripheral%2C+placental+sera+from+uninfected+women+than+in+sera+from+infected+women. assertion.
- assertion asSentence GATA-1+mediates+the+repression+of+VDR+and+enables+IL-4-dependent+moDC+differentiation. assertion.
- assertion asSentence The+IL-4+-34TT+and+-590TT+genotype+has+a+functional+effect+on+T+helper+%28Th%29+cells+of+patients+with+aggressive+periodontitis. assertion.
- assertion asSentence Stduy+find+an+association+and+linkage+of+the+IL4+-524+and+the+C1INH+480+polymorphisms+with+susceptibility+to+meningococcal+infection. assertion.
- assertion asSentence IL-4+increases+Fc+epsilon+receptor+type+I+%28FcepsilonRI%29+surface+expression+in+human+skin-derived+mast+cells+in+vitro. assertion.
- assertion asSentence Interleukin-4+up-regulates+monocyte+chemoattractant+protein-1+expression+in+vascular+endothelium+through+NADPH+oxidase-mediated+generation+of+reactive+oxygen+species. assertion.
- assertion asSentence Differential+use+of+chondroitin+sulfate+to+regulate+hyaluronan+binding+by+receptor+CD44+in+Inflammatory+and+Interleukin+4-activated+Macrophages. assertion.
- assertion asSentence IL-4+is+the+dominant+factor+that+induces+dendritic+cell+%28DC%29-SCRIPT+mRNA+expression+in+monocyte-derived+DCs. assertion.
- assertion asSentence No+genotypic+effects+on+total+serum+IgE+levels. assertion.
- assertion asSentence This+is+the+first+demonstration+of+sex-specific+association+of+the+two+foremost+genes+of+the+IL-4+signalling+cascade+with+chronic+inflammatory+arthropathies. assertion.
- assertion asSentence IL4R+SNPs%2C+rs1801275+and+rs1805010%2C+are+associated+with+rheumatoid+nodules+in+autoantibody-positive+African-American+rheumatoid+arthritis+patients+with+at+least+one+HLA-DRB1+allele+encoding+the+shared+epitope. assertion.
- assertion asSentence Transfectants+expressing+the+single+nucleotide+polymorphism+in+FCER2+exhibited+increased+IL-4Ralpha+expression+after+stimulation+through+CD23+compared+with+wild-type. assertion.
- assertion asSentence Increased+IL-5+expression+in+muscle+of+eosinophilic+myositis+patients+correlates+with+the+presence+of+activated+eosinophilic+granules+and+the+release+of+eosinophilic+major+basic+protein+in+muscle+biopsy+specimens. assertion.
- assertion asSentence IL-5+priming+enhances+Siglec-8-mediated+mitochondrial+and+ROS-dependent+eosinophil+apoptosis+and+eliminates+caspase+dependence. assertion.
- assertion asSentence Cyclic+AMP+signals+enhance+histone+H3+acetylation+at+the+IL-5+promoter+and+the+concerted+binding+of+GATA-3+and+NFATc+to+the+promoter. assertion.
- assertion asSentence Expression+of+Interleukin-6+%28IL-6%29+and+IL-6+receptor+mRNA+in+human+bone+samples+from+pre-+and+postmenopausal+women. assertion.
- assertion asSentence Interleukin-10+activates+the+transcription+factor+C%2FEBP+and+the+interleukin-6+gene+promoter+in+human+intestinal+epithelial+cells. assertion.
- assertion asSentence The+presence+of+high-expression+polymorphisms+at+position+-174+of+the+IL-6+gene+significantly+increases+the+risk+for+bronchiolitis+obliterans+syndrome+development+after+lung+transplantation. assertion.
- assertion asSentence MTmRNA+is+high+in+lymphocytes+from+elderly+people+coupled+with+high+IL-6%2C+low+zinc+ion+bioavailability%2C+decreased+NK+cell+activity+and+impaired+capacity+of+PARP-1+in+base+excision+DNA-repair. assertion.
- assertion asSentence There+is+a+positive+association+of+IL6+promoter+variant+with+bone+mineral+density+in+pre-menopausal+women. assertion.
- assertion asSentence IL-6+is+found+to+be+significantly+higher+in+the+cerebrospinal+fluid+of+the+%22delayed-responders%22+than+the+%22poor-responders%22+subtype+of+schizophrenics+and+the+controls. assertion.
- assertion asSentence Skeletal+muscle+fibers+are+the+dominant+cell+source+of+exercise-induced+release+of+IL-6. assertion.
- assertion asSentence Unglycosylated+humanhIL-6+is+as+potent+as+glycosylated+hIL-6+in+stimulating+B+cell+proliferation. assertion.
- assertion asSentence Pim1+and+Etk+are+required+for+IL6-induced+activation+of+androgen+receptor-mediated+transcription+in+prostate+cancer. assertion.
- assertion asSentence IL6+has+a+unique+role+in+the+progression+of+PCa. assertion.
- assertion asSentence Induced+and+expressed+in+human+alveolar+epithelial+cells+by+Legionella+pneumophila+after+invasion. assertion.
- assertion asSentence IL-6+produced+by+type+I+interferon%28IFN%29+dendritic+cells+controls+IFN-gamma+production+by+regulating+the+suppressive+effect+of+CD4%2B+CD25%2B+regulatory+T+cells. assertion.
- assertion asSentence IL-1beta%2C+IL-6+and+TNF-alpha+are+all+significantly+increased+in+hypoxic+ischemic+encephalopathy+infants+when+compared+to+controls. assertion.
- assertion asSentence Only+women+carrying+at+least+one+mutant+allele+of+both+polymorphisms+%28tumour+necrosis+factor-alpha+A+and+interleukin-6+C%29+have+a+significantly+elevated+mean+systolic+blood+pressure+and+diastolic+blood+pressure+at+the+end+of+pregnancy. assertion.
- assertion asSentence Patients+with+active+myeloma+induce+quantitatively+higher+levels+of+stromal+cell+IL-6+production+when+compared+with+those+with+monoclonal+gammopathy+of+undetermined+significance. assertion.
- assertion asSentence The+IL-6+concentration+increased+markedly+after+24+h+in+skin+areas+irradiated+with+a+twofold+minimal+erythemal+dose+%28MED%29+compared+to+areas+challenged+repeatedly+with+0.3+MED. assertion.
- assertion asSentence Carriers+of+the+IL-6+appeared+to+have+an+increased+risk+of+stroke+in+association+with+a+febrile+episode+prior+to+strokes. assertion.
- assertion asSentence IL-6+-634C%2FG+and+ICAM-1+469K%2FE+polymorphisms+synergistically+affect+the+susceptibility+for+endometriosis+in+the+Japanese+population. assertion.
- assertion asSentence Medroxyprogesterone+acetate+and+danazol+appeared+to+have+a+decreased+effect+on+the+suppression+of+IL-6+liberated+by+ESCs+in+adenomyosis. assertion.
- assertion asSentence Histamine+stimulates+IL-6+release+from+SW982+cells+by+binding+to+the+H1+receptor+and+this+is+coupled+to+the+PI%2FPKC+signal+transduction+pathway. assertion.
- assertion asSentence Elevated+IL-6+levels+occur+in+connection+with+bacterial+infections+after+kidney+transplantation. assertion.
- assertion asSentence Il-6+and+matrix+metalloproteinase-9+provide+a+link+between+inflammation%2C+matrix+degradation+and+the+development%2Fprogresion+of+acute+coronary+syndrome. assertion.
- assertion asSentence Azithromycin+suppressed+NF-kappaB+activation+and+reduced+synthesis+of+IL6%2FIL8+in+tracheal+cells+from+preterm+ventilated+infants. assertion.
- assertion asSentence There+is+a+relationship+between+VEGF%2C+TNF-alpha%2C+IL-6+and+the+development+of+the+diabetic+retinopathy+in+children+with+diabetes+mellitus+type+1. assertion.
- assertion asSentence The+IL-6%2FSTAT3+antiapoptotic+pathway+is+induced+by+short+exposure+to+bile+acid+cocktail+and+low+pH. assertion.
- assertion asSentence There%27s+a+relationship+between+inflammatory+activation+of+peripheral+blood+mononuclear+cells+%28enhanced+mRNA+expression+of+TNF-alpha+and+IL-6%29+and+renal+involvement+%28increased+urinary+albumin+excretion%29+in+type+2+diabetic+patients. assertion.
- assertion asSentence The+IL-6+gene+-597G%2FA+polymorphism+is+not+correlated+with+the+susceptibility+to+coronary+heart+disease. assertion.
- assertion asSentence The+implication+of+the+-174+interleukin-6+G%2FG+genotype+in+increasing+sites%2C+with+bleeding+of+gums+upon+probing%2C+is+demonstrated+in+Caucasian+pregnant+women. assertion.
- assertion asSentence IL6+-6331T+is+associated+with+increased+IL-6+concentrations+in+an+acute+inflammatory+state+via+a+mechanism+involving+binding+of+the+Oct-1+transcription+factor. assertion.
- assertion asSentence Plasma+Il-6+decreased+in+response+to+exercise+in+multiple+sclerosis+patients+and+controls. assertion.
- assertion asSentence Except+for+IL-6+and+eotaxin%2C+CLL+B-cells+and+their+normal+counterparts+produce+and+secrete+similar+amounts+of+cytokines+and+cytokine+receptors+in+vitro. assertion.
- assertion asSentence Bmx+is+involved+in+the+regulation+of+LPS-induced+IL-6+and+VEGF+production+via+mRNA+stabilisation+in+fibroblasts+from+rheumatoid+synovium. assertion.
- assertion asSentence The+IL-6+-572G%2FG+genotype+is+associated+with+higher+serum+IL-6+and+hs-CRP+concentrations+and+with+increased+risk+for+type+2+diabetes. assertion.
- assertion asSentence IL6+gene-wide+haplotype+is+associated+with+susceptibility+to+adult+respiratory+distress+syndrome. assertion.
- assertion asSentence Zinc+deficiency+increases+activation+of+NF-kappaB+and+up-regulates+expression+of+VEGF%2C+IL-6+and+IL-8+in+androgen-independent+PC-3+and+DU-145+prostate+cancer+cells. assertion.
- assertion asSentence Insulin+stimulates+interleukin-6+expression+and+release+in+LS14+human+adipocytes. assertion.
- assertion asSentence IL-6+is+necessary+for+the+expansion+of+pancreatic+alpha-cell+mass+in+response+to+high-fat+diet+feeding. assertion.
- assertion asSentence Urinary+IL-6+is+elevated+whether+the+stone+is+present+or+not. assertion.
- assertion asSentence Visfatin+upregulate+secretion+of+MCP-1and+IL-6+in+human+umbilical+vein+endothelial+cells. assertion.
- assertion asSentence IL-6+related+gene+variations+influence+susceptibility+to+multiple+myeloma. assertion.
- assertion asSentence Expression+levels+of+IL6+in+circulating+lymphocytes+are+not+sufficiently+specific+to+diagnose+transitory+postsurgical+complications+such+as+symptomatic+infection+after+liver+transplantation. assertion.
- assertion asSentence High+interleukin-6+is+associated+with+cytomegalovirus+infection+in+lung+transplant+patients. assertion.
- assertion asSentence ERK1%2F2+activation+as+the+key+pathway+through+which+IL-6+regulates+both+mesenchymal+stem+cells+proliferation+and+inhibition+of+differentiation. assertion.
- assertion asSentence Strong+association+between+circulating+levels+of+IL-6+and+plasma+ceramide+concentrations+in+patients+with+established+coronary+heart+disease. assertion.
- assertion asSentence IL-6-174G%2FC+gene+polymorphism+is+not+found+in+children+in+Wenzhou+area. assertion.
- assertion asSentence Increased+plasma+levels+of+interleukin-6+are+associated+with+left+ventricular+diastolic+dysfunction. assertion.
- assertion asSentence SNPs+in+the+SLC6A4+gene+significantly+increased+depressive+symptoms+and+elevated+IL-6+plasma+levels. assertion.
- assertion asSentence Higher+levels+of+circulating+IL-6+is+associated+with+negative+response+to+administration+with+recombinant+human+erythropoietin+and+fatigued+cancer+patients. assertion.
- assertion asSentence Individual+KSHV-encoded+miRNA+induce+IL-6+secretion+by+human+myelomonocytic+cells. assertion.
- assertion asSentence Umbilical+cord+levels+for+IL-6+are+increased+in+low+risk+labouring+patients+at+term+in+the+absence+of+evident+infection. assertion.
- assertion asSentence p38%2C+activated+by+IL-1beta%2C+TNFalpha+or+environmental+stress%2C+impairs+IL-6-induced+JAK%2FSTAT+signalling+through+phosphorylation+of+the+common+cytokine+receptor+subunit+gp130+and+its+subsequent+internalisation+and+degradation. assertion.
- assertion asSentence IL-6%2FSTAT3%2FTFF3+signaling+is+involved+in+human+biliary+epithelial+cell+migration+and+wound+healing. assertion.
- assertion asSentence IL-6+responded+quickly+to+the+carefully+monitored+exercise+intervention+%28within+weeks%29+and+required+only+moderate-intensity+exercise. assertion.
- assertion asSentence PIM2+controls+the+expression+of+the+pro-inflammatory+cytokine+IL-6. assertion.
- assertion asSentence The+early+serum+levels+of+TNF-alpha+and+IL-6+in+ACI+markedly+increase+and+are+closely+correlated+with+acute+cerebral+infarction+severity. assertion.
- assertion asSentence Impaired+IL6+metabolism+leads+to+increased+IL6+in+blood+and+urine+and+is+a+biomarker+for+acute+kidney+injury+following+cardiac+surgery. assertion.
- assertion asSentence Free+bile+acids+can+inhibit+the+expression+of+IL-6+and+the+cell+viability+in+cholangiocarcinoma+cells. assertion.
- assertion asSentence Hyperresponsiveness+of+glycoprotein+%28gp%29130%28F%2FF%29+knock-in+mutant+mice+to+lipopolysaccharide+involves+specific+upregulation+of+IL-6+in+a+gp130%2FSTAT3-+and+TLR4%2FMyD88-dependent+manner. assertion.
- assertion asSentence Siltuximab+effectively+blocks+the+IL-6%2FStat3+signaling+pathway+in+ovarian+cancer. assertion.
- assertion asSentence Extracellular+hepatitis+C+virus+core+protein+activates+STAT3+in+human+monocytes%2Fmacrophages%2Fdendritic+cells+via+an+IL-6+autocrine+pathway. assertion.
- assertion asSentence IL-6+G-174C+and+IFN-gamma+T%2B874A+gene+polymorphisms+have+predictive+values+for+acute+rejection+after+renal+transplantation+in+Iranian+patients. assertion.
- assertion asSentence Acute+psychological+stress+affects+LPS-stimulated+IL-6+and+TNF-alpha+gene+expression. assertion.
- assertion asSentence Increased+risk+of+multiple+sclerosis+is+found+for+IL6-174+CC+homozygotes. assertion.
- assertion asSentence IL-6+plays+a+role+in+ANGII-mediated+hypertension. assertion.
- assertion asSentence Increased+IL-6+levels+are+associated+with+bone+turnover+in+a+case+of+a+CD34%2B%2FCD117%2B%2Fmyeloperoxidase%28%2Bdim%29+acute+myeloid+leukemia+presenting+with+severe+hypercalcemia+and+lumbar+spine+fractures. assertion.
- assertion asSentence IL-6-6331+polymorphism+is+involved+in+susceptibility+to+developing+gastric+cancer. assertion.
- assertion asSentence Ketamine+does+not+inhibit+interleukin-6+synthesis+in+hepatic+resections+requiring+a+temporary+porto-arterial+occlusion+%28Pringle+manoeuvre%29. assertion.
- assertion asSentence IL-6+is+involved+in+the+etiology+of+intervertebral+disc+degeneration+among+young+adults. assertion.
- assertion asSentence Thiazolidinediones+decrease+the+proinflammatory+cytokines+IL-6+and+IL-8+in+endometrial+stromal+cells+via+a+PPAR-gamma-independent+mechanism. assertion.
- assertion asSentence Proteolysis+of+interleukin-6+receptor+%28IL-6R%29+by+Porphyromonas+gingivalis+cysteine+proteinases+%28gingipains%29+inhibits+interleukin-6-mediated+cell+activation. assertion.
- assertion asSentence Asp358Ala+polymorphism+of+the+IL6R+associates+with+type+2+diabetes+in+Danish+whites. assertion.
- assertion asSentence IL-1beta-+and+TNFalpha-mediated+induction+of+IL-6R+shedding+in+osteoblast-like+cells+is+at+least+partly+dependent+on+tumor+necrosis+factor+alpha-converting+enzyme+activation. assertion.
- assertion asSentence The+IL-6+classic-+and+trans-signaling+pathways+have+an+important+role+in+corneal+sterile+inflammation+and+wound+healing. assertion.
- assertion asSentence Single+nucleotide+polymorphisms+rs1143634+of+IL-1beta+and+rs8192284+of+IL-6+receptor+act+as+susceptibility+variations+in+Korean+non-Sjogren+dry+eye+patients. assertion.
- assertion asSentence Patients+at+risk+of+acute+tubular+necrosis+after+kidney+transplanation+display+low+levels+of+soluble+glycoprotein+130. assertion.