Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Serum+CRP+and+urinary+NGF+levels+are+elevated+in+patients+with+overactive+bladder+and+interstitial+cystitis%2Fbladder+pain+syndrome. assertion.
- assertion asSentence Recognition+and+functional+activation+of+the+human+IgA+receptor+%28FcalphaRI%29+by+C-reactive+protein. assertion.
- assertion asSentence A+role+for+CRP+in+promoting+differentiation+of+human+monocytes+toward+a+proinflammatory+M1+phenotype. assertion.
- assertion asSentence Higher+levels+of+CRP+are+independently+associated+with+an+increased+risk+of+perioperative+myocardial+damage+and+early+adverse+cardiovascular+events+in+patients+undergoing+elective+vascular+surgery. assertion.
- assertion asSentence Procalcitonin%2C+C-reactive+protein+and+neopterin+levels+vary+depending+on+the+clinical+status+in+chronic+obstructive+pulmonary+disease. assertion.
- assertion asSentence Increase+in+inflammation+mediatiors+Il6%2FC-reactive+protein+is+associated+with+the+loss+of+skeletal+muscle+in+free-living+non-sarcopenic+older+men+and+women. assertion.
- assertion asSentence High+CRP+levels+are+associated+with+significantly+greater+embolization+during+carotid+artery+stenting+in+symptomatic+patients%2C+particularly+in+dishomogenous+plaque. assertion.
- assertion asSentence The+ratio+of+C-reactive+protein+to+prealbumin+is+independently+associated+with+mortality+after+adjustment+for+age%2C+gender%2C+sepsis+and+sequential+organ+failure+assessment. assertion.
- assertion asSentence Preoperative+CRP+level+greater+than+20+mg%2FL+is+significantly+associated+with+worse+survival+than+undetectable+CRP+in+patients+with+stage+I+or+II+non-small+cell+lung+cancer. assertion.
- assertion asSentence Elevated+C-reactive+protein+predicted+contrast-induced+nephropathy+after+percutaneous+coronary+intervention+in+myocardial+infarction. assertion.
- assertion asSentence CRP+peptide+impacts+neutrophil+interactions+with+endothelial+cells+and+platelets%2C+critical+inflammatory+events+triggering+acute+coronary+artery+disease. assertion.
- assertion asSentence Elevated+levels+of+CRP+and+exposure+to+HSV-1+are+associated+with+the+severity+of+cognitive+impairment+in+schizophrenia. assertion.
- assertion asSentence CRP+gene+-717AG+or+GG+genotypes+is+associated+with+cardiovascular+benefit+to+Chinese+peritoneal+dialysis+patients+with+cholesterol+levels+of+200+mg%2Fdl+or+greater. assertion.
- assertion asSentence The+elevation+of+CRP+before+treatment+predicts+a+poor+prognosis+in+patients+with+locoregionally+advanced+laryngeal+carcinoma+treated+with+chemoradiotherapy. assertion.
- assertion asSentence Elevated+hsCRP+levels+are+independently+associated+with+risk+of+prediabetes+in+Indians. assertion.
- assertion asSentence Nr2e3+is+a+dual-function+transcriptional+regulator+that+acts+in+concert+with+Crx+to+promote+and+maintain+the+function+of+rod+photoreceptors. assertion.
- assertion asSentence The+carboxyl-terminal+domain+of+human+cryptochrome+2+is+intrinsically+unstructured+in+solution%2C+consistent+with+its+presumed+role+as+a+signal+transduction+domain. assertion.
- assertion asSentence Mutants+of+alphaA-crystallin+form+aggregates+and+aggresomes. assertion.
- assertion asSentence A+missense+mutation+in+CRYAA+is+associated+with+congenital+anterior+polar+cataract+in+a+Chinese+family. assertion.
- assertion asSentence CRYAB+is+a+nuclear+speckle+component+in+unstressed+cells+in+tissue+culture. assertion.
- assertion asSentence Proper+orientation+of+residues+contributing+to+RS-1+and+RS-2+sites+in+alphaB-crystallin+is+important+for+homooligomerization+and+optimal+subunit+interaction+with+alphaA-crystallin. assertion.
- assertion asSentence SCF%28FBX4-alphaB+crystallin%29+is+an+E3+ubiquitin+ligase+that+promotes+ubiquitin-dependent+degradation+of+Thr286-phosphorylated+cyclin+D1. assertion.
- assertion asSentence Interactive+domains+in+alphaB+crystallin+have+multiple+functions+in+stabilizing+the+cytoskeleton+and+protecting+cytosolic+proteins+from+unfolding. assertion.
- assertion asSentence Transgenic+mice+overexpressing+cardiac-specific+human+mutant+CryAB+%28hR120GCryAB%29+recapitulate+lethal+human+cardiomyopathy+with+reductive+stress+and+dysregulation+of+glucose-6-phosphate+dehydrogenase. assertion.
- assertion asSentence The+presence+of+an+intact+C-terminus+is+essential+for+the+formation+of+fully+integrated+heteroaggregates+with+equal+proportion+of+alphaA+and+alphaB+subunits. assertion.
- assertion asSentence Presence+of+measurable+interactions+between+MIP26+and+all+crystallins%2C+with+the+extent+of+interactions+decreasing+from+alphaA-+and+alphaB-crystallin+to+betaB2-+and+gammaC-crystallin. assertion.
- assertion asSentence Inhibition+of+the+early+stage+of+beta2m+aggregation+by+alphaB-crystallin+does+not+necessarily+require+a+mechanicistic+chaperon-like+action+implying+one-to-one+binding. assertion.
- assertion asSentence Phosphorylated+alphaB-crystallin+interacts+with+Bcl-2+and+prevents+the+translocation+of+Bcl-2+to+mitochondria. assertion.
- assertion asSentence The+alphaB-crystallin+oligomers+formed+long-lived+stable+complexes+with+their+gammaD-crystallin+substrates. assertion.
- assertion asSentence The+T5P+mutation+obviously+changes+conformation+and+decreases+conformational+stability. assertion.
- assertion asSentence The+heterozygous+109C+to+A+CRYGD+missense+mutation+is+associated+with+a+distinct+crystalline+cataract+in+two+US+Caucasian+pedigrees. assertion.
- assertion asSentence p38+MAPK+modulates+STAT1+phosphorylation+in+IFN-gamma+signaling+in+fetal+brain+astrocytes. assertion.
- assertion asSentence p38+MAP+kinase+plays+a+pivotal+role+in+the+signal+transduction+pathways+regulating+the+number+of+endothelial+progenitor+cells+ex+vivo. assertion.
- assertion asSentence Effect+of+hibuscus+polyphenol+extracs+in+human+gastric+carcinoma+cells+is+mediated+via+p53+signaling+and+p38+MAPK%2FFasL+cascade+pathway. assertion.
- assertion asSentence Reduction-oxidation+regulation+ofgamma-glutamylcysteine+synthetase+expression+is+mediated+by+p38+mitogen-activated+protein+kinase+signaling. assertion.
- assertion asSentence Importantly%2C+inhibition+of+p38alpha+MAPK+blocks+the+release+of+vascular+endothelial+growth+factor+and+suppresses+tumor-promoted+endothelial+cell+migration%2C+a+key+step+in+angiogenesis. assertion.
- assertion asSentence p38+regulates+PPARgamma+expression+and+activity+in+term+human+trophoblasts. assertion.
- assertion asSentence Mapk14+antagonizes+Mapk12+activity+through+c-jun-dependent+ubiquitin-proteasome+pathways+in+regulating+Ras+transformation+and+stress+response. assertion.
- assertion asSentence Shiga+toxin+activates+a+signaling+cascade+involving+cross+talk+between+Ca%282%2B%29+and+p38%2C+to+regulate+its+trafficking+to+the+Golgi+apparatus. assertion.
- assertion asSentence UVB+irradiation+leads+to+an+activated+p38+MAPK+that+is+regulated+in+an+IGF-1R-dependent+manner%2C+leading+to+NF-kappaB+p50%3ARelA%2Fp65+activation+and+a+survival+phenotype. assertion.
- assertion asSentence p38+MAP+kinase+down-regulates+extracellular+signal-regulated+kinase+via+activation+of+MKP-3+in+human+monocytes+exposed+to+asbestos+to+enhance+TNF-alpha+gene+expression. assertion.
- assertion asSentence Inhibition+of+ERK1%2F2+and+activation+of+p38+are+involved+in+diallyl+disulfide+induced+apoptosis+of+leukemia+HL-60+cells. assertion.
- assertion asSentence p38+MAPK+is+the+key+signal+molecule+in+the+inflammatory+reaction+induced+by+Haemophilus+influenzae. assertion.
- assertion asSentence p38+MAP+kinase+controls+EGF+receptor+downregulation+via+phosphorylation+at+Ser1046%2F1047. assertion.
- assertion asSentence p38+is+active+when+only+the+Thr180+residue+is+phosphorylated. assertion.
- assertion asSentence p38-MAPK+signaling+pathway+is+involved+in+the+bruceine-D-induced+apoptosis+in+pancreatic+cancer+cells. assertion.
- assertion asSentence Cdc25A+degradation+depended+on+Ser75-Cdc25A+phosphorylation+caused+by+p38MAPK+and+Chk2. assertion.
- assertion asSentence Cilostazol+protects+endothelial+cells+against+lipopolysaccharide-induced+apoptosis+through+ERK1%2F2-+and+P38+MAPK-dependent+pathways. assertion.
- assertion asSentence Exposure+of+cultured+human+renal+proximal+tubular+cells+to+high+glucose+increased+Akt+and+pMAPK+phosphorylation+coinciding+with+increased+apoptosis. assertion.
- assertion asSentence Kiss-1+suppresses+MMP-9+expression+by+activating+the+p38+MAP+kinase+signaling+pathway. assertion.
- assertion asSentence Hsp90-Cdc37+complex+acta+as+an+endogenous+regulator+of+noncanonical+p38alpha+activity. assertion.
- assertion asSentence The+p38+MAPK+is+critical+for+the+growth+inhibitory+effect+of+UC-MSCs+on+leukemic+tumor+cells. assertion.
- assertion asSentence p38+MAPK+signaling+pathway+is+an+important+contributor+to+the+abnormal+differentiation+of+DC+in+Primary+effusion+lymphoma+%28PEL%29. assertion.
- assertion asSentence Induction+of+autophagy+by+H2O2+depends+on+the+induction+of+intracellular+production+of+reactive+oxygen+species+%28ROS%29+and+activation+of+the+p38+mitogen-activated+protein+kinase+alpha+%28p38+MAPKalpha%29+pathway. assertion.
- assertion asSentence p38+MAPK+negatively+regulates+EGF-induced+MMP-1+expression+by+suppressing+the+activations+of+ERK+and+JNK. assertion.
- assertion asSentence Inhibition+of+Notch3+signalling+induces+rhabdomyosarcoma+cell+differentiation+promoting+p38+phosphorylation+and+p21%28Cip1%29+expression+and+hampers+tumour+cell+growth+in+vitro+and+in+vivo. assertion.
- assertion asSentence A+distinct+interaction+mode+revealed+by+the+crystal+structure+of+the+kinase+p38alpha+with+the+MAPK+binding+domain+of+the+phosphatase+MKP5. assertion.
- assertion asSentence Fluorophore+labeled+kinase+detects+ligands+that+bind+within+the+MAPK+insert+of+p38alpha+kinase. assertion.
- assertion asSentence IFN-gamma+shifts+monocyte+differentiation+to+macrophages+rather+than+DCs+through+autocrine+M-CSF+and+IL-6+production. assertion.
- assertion asSentence Monocytes+promote+angiogenesis+via+M-CSF-induced+vascular+endothelial+growth+factor+production. assertion.
- assertion asSentence INI1%2FhSNF5%2FBAF47+functions+in+activation+of+the+colony+stimulating+factor+1+%28CSF1%29+promoter+in+HeLa+cells. assertion.
- assertion asSentence CSF-1+stimulates+extracellular+signal-regulated+kinase+5+%28ERK5%29+activation+in+macrophages. assertion.
- assertion asSentence Nuclear+c-Abl+kinase+can+activate+CSF-1+gene+transcription+by+regulating+AP-1+activity+in+the+signaling+events+induced+by+L-selectin+ligation. assertion.
- assertion asSentence Macrophage+Colony+Stimulating+Factor+and+Monocyte+Chemoattractant+Protein+are+elevated+in+sera+of+intrinsic+asthmatics+compared+to+normal+controls. assertion.
- assertion asSentence Inhibitory+activity+of+lead+compounds+and+drug+candidates%2C+such+as+ABT-869%2C+against+the+CSF-1R+protein+in+situ. assertion.
- assertion asSentence Expression+of+M-CSF%2C+CSF-1R+and+CD3+is+a+significant+prognostic+factor+in+primary+prostatic+cancers+by+predicting+the+development+of+metastases. assertion.
- assertion asSentence GM-CSF+inhibits+prolonged+glucocorticoid-induced+activation+of+eosinophil+c-Jun+NH2-terminal+kinase+and+preserves+the+expression+of+eosinophil+antiapoptotic+protein+X-linked+inhibitor+of+apoptosis. assertion.
- assertion asSentence GM-CSF+is+associated+with+the+expression+of+proliferation+vascularization+in+memingioma. assertion.
- assertion asSentence Protein+kinase+C+plays+a+role+in+activation+of+granulocyte+macrophage-colony+stimulating+factor+in+lung+cancer. assertion.
- assertion asSentence GM-CSF-stimulated+CD34%28%2B%29+cell+proliferation+is+regulated+by+the+JAK%2FSTAT3%2Fsurvivin+signaling+pathway. assertion.
- assertion asSentence GM-CSF+can+both+synergize+with+TNFalpha+in+the+case+of+expression+of+IL1-RA+and+antagonize+in+the+case+of+CD83. assertion.
- assertion asSentence Expression+of+CFS2+by+decidua+cells+contributes+to+host+defense+in+patients+with+chorioamnionitis. assertion.
- assertion asSentence GM-CSF+is+expressed+in+normal+and+glaucomatous+human+retina. assertion.
- assertion asSentence The+cytosolic+domain+of+the+hGM+Ralpha+chain+is+required+for+differentiation+mediated+by+activation+of+the+hGM+Ralpha%2C+beta%28c%29+receptor+complex. assertion.
- assertion asSentence Effect+of+in+vivo+infusion+of+granulocyte+colony-stimulating+factor+on+immune+function. assertion.
- assertion asSentence G-CSF-mediated+hematopoietic+stem%2Fprogenitor+cells+%28HSPC%29+mobilization+occurs+in+part+through+the+HGF%2Fc-Met+axis+in+HSPC+and+myeloid+cells%2C+eliciting+increased+production+of+matrix-degrading+enzymes+and+subsequently+facilitating+egress+of+HSPC. assertion.
- assertion asSentence High+serum+granulocyte+Colony-Stimulating+Factor+is+associated+with+non+small+cell+lung+cancer. assertion.
- assertion asSentence G-CSF-induced+MMP-2+upregulation+and+invasive+phenotype+is+mediated+by+Rac1. assertion.
- assertion asSentence Prdx4+inhibits+G-CSF-induced+signalling+and+proliferation+in+myeloid+progenitors. assertion.
- assertion asSentence The+C-terminus+of+the+G-CSF+receptor%2C+truncated+in+patients+with+severe+congenital+neutropenia%2Facute+myeloid+leukemia%2C+is+required+for+SH2-containing+phosphatase-1+suppression+of+G-CSF-stimulated+Stat+activation. assertion.
- assertion asSentence Gemcitabine+can+enhance+in+vitro+the+expression+rate+of+bone+marrow+G-CSFR+in+chronic+myeloid+leukemia+patients+at+chronic+or+blastic+phases. assertion.
- assertion asSentence The+human+growth+hormone%2Fchorionic+somatomammotropin+at+chromosome+17+is+implicated+in+regulation+of+postnatal+and+intrauterine+growth. assertion.
- assertion asSentence The+interaction+of+c-Src+with+LNX1+depends+on+the+C-terminal+PDZ+ligand+of+c-Src. assertion.
- assertion asSentence Absolute+requirement+for+c-Src+in+villin-induced+regulation+of+cell+migration+of+intestinal+tumor+cells. assertion.
- assertion asSentence The+association+between+Furin+and+its+substrate+MT1-MMP+is+regulated+by+PDGFR+stimulation+and+c-Src. assertion.
- assertion asSentence Casein+Kinase+1+phosphorylates+serine+56+of+yellow+fever+virus+methyltransferase. assertion.
- assertion asSentence CKI+epsilon%28tau%29+is+a+highly+specific+gain-of-function+mutation+that+increases+in+vivo+phosphorylation+and+degradation+of+the+circadian+regulators+period+%28PER%291+and+PER2. assertion.
- assertion asSentence CK1epsilon+regulates+the+cellular+levels+of+Cdc25A+in+parallel+with+Chk1-dependent+Cdc25A+degradation%2C+contributing+to+the+precise+control+of+cell+division. assertion.
- assertion asSentence CK2+regulates+NKX3-1+in+prostate+cells. assertion.
- assertion asSentence KIF5C%2C+a+member+of+the+kinesin+1+heavy+chain+family%2C+is+a+substrate+for+protein+kinase+CK2. assertion.
- assertion asSentence Extracellular+protein+kinase+CK2+binds+to+the+extracellular+domain+of+NRP1+which+is+also+phosphorylated+by+CK2+both+in+vitro+and+in+vivo. assertion.
- assertion asSentence CK2+is+a+central+regulator+of+topo+I+hyperphosphorylation. assertion.
- assertion asSentence Persistence+of+high+CK2+level+in+R+%28resistant%29-CEM%2C+as+opposed+to+S+%28sensitive%29-CEM%2C+is+accompanied+by+the+presence+of+an+immunospecific+form+of+Cdc37. assertion.
- assertion asSentence Ets+motifs+play%2C+in+cooperation+with+Sp+motif+clusters%2C+a+central+role+in+regulating+CK2alpha%27+gene+transcription. assertion.
- assertion asSentence CK2-dependent+phosphorylation+controls+the+nuclear+localization%2C+aggregation+and+stability+of+ataxin-3. assertion.
- assertion asSentence A+physiological+function+of+ADAMTS5+in+dermal+fibroblasts+is+to+maintain+optimal+versican+content+and+PCM+volume+by+continually+trimming+versican+in+hyaluronan-versican+aggregates. assertion.
- assertion asSentence NG2+is+abundantly+distributed+in+the+intestinal+subepithelial+myofibroblasts+layer+of+the+mouse+and+human+intestines. assertion.
- assertion asSentence Relationship+between+serum+cystatin+C+and+creatinine+in+kidney+and+liver+transplant+patients. assertion.
- assertion asSentence A+significant+elevation+in+the+content+of+cystatin+C+is+measured+in+the+cerebrospinal+fluid+of+human+patients+experiencing+persistent+pain+of+strong+intensity. assertion.
- assertion asSentence Serum+creatinine+is+a+more+efficacious+marker+than+serum+cystatin+C+to+assess+renal+function+after+renal+transplantation. assertion.