Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence A+valid+serum+marker+for+glomerular+filtration+rate+in+renal+transplantation. assertion.
- assertion asSentence Modification+of+Diet+in+Renal+Disease+%28MDRD%29+is+equivalent+to+cystatin+C+measurement+as+a+measure+of+glomerular+filtration+rate. assertion.
- assertion asSentence Creatinine+measurement+is+cheaper+and+glomerular+filtration+rate+is+preferred+to+cystatin+C+levels+in+kidney+donors. assertion.
- assertion asSentence N-acetylcysteine%2C+in+doses+currently+recommended+for+prophylaxis+of+contrast-induced+nephropathy%2C+has+no+effect+on+serum+creatinine+or+cystatin+C+levels. assertion.
- assertion asSentence Serum+cystatin+C+is+raised+as+early+as+the+second+trimester+in+women+who+subsequently+develop+pre-eclampsia+in+third+trimester. assertion.
- assertion asSentence HIV-infected+children+have+higher+serum+cystatin+C+level+and+lower+gomerular+filtration+rate+compared+to+controls. assertion.
- assertion asSentence Low+levels+of+plasma+cystatin+C+are+found+to+predict+significant+conversion+to+dementia+in+patients+with+mild+cognitive+impairment. assertion.
- assertion asSentence The+inflammatory+status+of+a+patient+does+not+influence+the+role+of+cystatin+C+as+a+marker+of+successful+aging%2C+nor+of+glomerular+filtration+rate. assertion.
- assertion asSentence Stringent+regulation+of+cathepsins+S+and+D%2C+two+proteases+involved+in+antigen+presentation%2C+is+crucial+to+engage+cell+commitment+to+either+route. assertion.
- assertion asSentence The+cysteine+protease+inhibitor+cystatin+M%2FE+is+a+key+regulator+of+a+biochemical+pathway+that+leads+to+epidermal+terminal+differentiation. assertion.
- assertion asSentence Cystatin+M+%28CST6%29+tumor+suppressor+gene+is+concurrently+down-regulated+with+other+loci+in+breast+epithelial+cells+cocultured+with+cancer-associated+fibroblasts. assertion.
- assertion asSentence Methylation+of+cystatin+M+promoter+is+associated+with+breast+cancer. assertion.
- assertion asSentence Cystatin+A+suppresses+UVB-induced+apoptosis+of+keratinocytes+by+the+inhibition+of+caspase+3+activation. assertion.
- assertion asSentence At+pH+7.0+the+mutant+H75W+folded+in+three+kinetic+phases+to+a+native-like+intermediate%2C+analogous+to+folding+of+stefin+B+at+pH+4.8. assertion.
- assertion asSentence Elevated+StefA+mRNA+level+is+associated+with+invasive+glioblastoma. assertion.
- assertion asSentence A+deletion+variant+of+BARD1%2C+a+BRCA1+partner%2C+occurs+in+cells+and+interacts+with+and+colocalizes+with+CstF-50. assertion.
- assertion asSentence The+Polycomb-group+gene+Rae28+sustains+Nkx2.5%2FCsx+expression+and+is+essential+for+cardiac+morphogenesis. assertion.
- assertion asSentence NY-ESO-1+mRNA+expression%2C+specific+antibodies+and+CD8+T+cell+responses+in+advanced+prostate+cancer. assertion.
- assertion asSentence NY-ESO-1+spontaneously+induces+HLA-DP4-restricted+CD4%2B+Th1+and+Th2+responses+in+a+significant+proportion+of+patients+with+epithelial+ovarian+cancer. assertion.
- assertion asSentence NY-ESO-1%2Fimmune+complexes+induce+cross-presentation+of+HLA-A2-negative+and+HLA-Cw3-restricted+epitopes+via+a+proteasome-dependent+pathway. assertion.
- assertion asSentence ESO+9V+peptide+isoform+is+more+efficient+in+inducing+conjugate+formation+and+cytolytic+granule+polarization+than+the+ESO+9L+isoform. assertion.
- assertion asSentence A+versatile+prime-boost+vaccine+strategy+allows+the+generation+of+powerful%2C+high-avidity+tumor-associated+immunodominant+NY-ESO-1-transgene+specific+CD8-positive+cytotoxic+T+cell+responses. assertion.
- assertion asSentence CtBP+proteins+repress+transcription+in+a+histone+deacetylase+dependent+or+independent+manner. assertion.
- assertion asSentence The+corepressor+C-terminal-binding+protein+binds+the+MLL+repression+domain. assertion.
- assertion asSentence Homeodomain-interacting+protein+kinase-2+%28HIPK2%29+mediates+CtBP+phosphorylation+and+degradation+in+UV-triggered+apoptosis. assertion.
- assertion asSentence Plays+a+critical+role+in+the+fission+step+of+coat+protein+I+vesicle+formation+from+Golgi+membrane. assertion.
- assertion asSentence HDGF+functions+as+a+transcriptional+repressor+of+the+SMYD1+gene+through+interaction+with+the+transcriptional+corepressor+CtBP. assertion.
- assertion asSentence In+breast+tumours%2C+both+major+CTBP1+mRNA+splice+forms+are+variably+expressed. assertion.
- assertion asSentence Perioperative+plasma+brain+natriuretic+peptide+and+cardiotrophin-1+measured+in+off-pump+coronary+artery+bypass. assertion.
- assertion asSentence CTGF+interacts+with+the+cytoskeletal+protein+actin+in+chondrocytes. assertion.
- assertion asSentence CTGF+inhibits+metastasis+and+invasion+of+human+lung+adenocarcinoma+by+a+CRMP-1-dependent+mechanism. assertion.
- assertion asSentence TGF-beta+1-stimulated+CTGF+expression+is+mediated+by+mechanisms+involving+ERK+and+JNK+pathways+and+is+downregulated+by+IL-4+and+IL-13+through+modulation+of+Smad+and+ERK+signals. assertion.
- assertion asSentence CTGF+plays+a+major+role+in+the+pathogenesis+of+progressive+fibrosis+in+biliary+atresia. assertion.
- assertion asSentence Bradykinin+and+angiotensin+II+lower+CTGF+mRNA+expression+below+basal+levels+over+a+span+of+4+hours. assertion.
- assertion asSentence Overexpression+of+CTGF+is+one+of+the+most+important+features+of+idiopathic+portal+hypertension. assertion.
- assertion asSentence Gastrointestinal+carcinoid+tumor+fibrosis+is+a+CTGF%2FTGFbeta1-mediated+stellate+cell-driven+fibrotic+response. assertion.
- assertion asSentence Antisense+oligonucleotides+inhibit+CTGF+and+fibronectin+expression+in+human+tenon%27+s+capsule+fibroblasts+induced+by+transforming+growth+factor+beta2. assertion.
- assertion asSentence CCN2+expression+occurred+via+activation+of+p38+mitogen-activated+protein+%28MAP%29+kinase+and+the+downstream+transcription+factor+ATF-2. assertion.
- assertion asSentence A+regulatory+role+for+miR-18a+in+chondrocytic+differentiation+through+CCN2. assertion.
- assertion asSentence Ras%2FMAP+kinase+pathway%2C+specifically+through+N-Ras%2C+mediates+TGFbeta1+auto-induction+and+TGFbeta1-induced+CTGF+expression+in+human+renal+tubule+epithelial+cells. assertion.
- assertion asSentence Aberrant+connective+tissue+growth+factor+production+induced+by+TNFalpha+plays+a+central+role+for+the+abnormal+osteoclastic+activation+in+RA+patients. assertion.
- assertion asSentence CTGF+and+TSP-1+expression+are+elevated+in+human+heart+failure. assertion.
- assertion asSentence Extracellular+acidification+induces+CTGF+production+through+the+OGR1%2FG%28q%2F11%29+protein+and+inositol-1%2C4%2C5-trisphosphate-induced+Ca%282%2B%29+mobilization+in+human+airway+smooth+muscle+cells. assertion.
- assertion asSentence JNK+mediates+the+expression+of+CTGF+and+corneal+scarring+in+corneal+wound+healing. assertion.
- assertion asSentence Remission+of+Graves%27+hyperthyroidism+and+A%2FG+polymorphism+at+position+49+in+exon+1+of+cytotoxic+T+lymphocyte-associated+molecule-4+gene. assertion.
- assertion asSentence CTLA4+exon+1+dimorphism+is+associated+with+primary+progressive+multiple+sclerosis. assertion.
- assertion asSentence Role+of+polymorphism+at+this+site+in+immunologic+response+to+chronic+hepatitis+C+therapy+with+interferon+alfa+and+ribavirin. assertion.
- assertion asSentence Polymorphisms+of+CTLA4+%28CTLA-4-318+and+CTLA-4+%2B+49%29+do+not+affect+the+risk+of+developing+multiple+sclerosis+and+have+no+influence+on+the+course+and+progression+of+disease. assertion.
- assertion asSentence CTLA-4+49+A-G+polymorphism+is+associated+with+rheumatoid+arthritis+in+Chinese+patients+from+Taiwan. assertion.
- assertion asSentence The+cytoplasmic+domain+of+CTLA-4+has+the+capacity+to+assemble+two+different+signalosomes+on+the+T-cell+surface%2C+one+inhibitory+and+the+other+activating%2C+in+response+to+two+different+types+of+ligands. assertion.
- assertion asSentence A+CTLA4high+genotype+is+associated+with+myasthenia+gravis+in+thymoma+patients. assertion.
- assertion asSentence CTLA-4+polymorphism+is+not+associated+with+UC+in+the+Iranian+population. assertion.
- assertion asSentence CTLA-4+is+a+major+thyroid+autoantibody+diathesis+susceptibility+gene+in+patients+with+Hashimoto%27s+thyroiditis. assertion.
- assertion asSentence Prolonged+kidney+graft+survival+when+tranfected+into+rats. assertion.
- assertion asSentence Carriage+of+the+%2B49G+single+nucleotide+polymorphism+of+the+cytotoxic+T-lymphocyte+antigen+4+gene+in+heterozygous+or+in+homozygous+form+does+not+confer+risk+either+for+Crohn%27s+disease+or+for+ulcerative+colitis+in+the+Hungarian+population. assertion.
- assertion asSentence CTLA-4+genetic+polymorphisms+are+associated+with+the+susceptibility+to+Vogt-Koyanagi-Harada+syndrome. assertion.
- assertion asSentence Contribution+of+the+CTLA4+gene+to+disease+susceptibility+is+distinct+between+fulminant+type+1+diabetes+and+classic+type+1A+diabetes. assertion.
- assertion asSentence There+is+no+association+of+CTLA-4+with+either+-318C%2FT+or+49A%2FG+polymorphism+in+patients+with+Behet%27s+disease+or+intermediate+uveitis. assertion.
- assertion asSentence The+panenteritis+associated+with+injection+of+alpha-CTLA-4+mAbs+demonstrates+histology+resembling+autoimmune+enteropathy. assertion.
- assertion asSentence Cell-permeable+dominant+negative+mutant+form+of+ZAP-70+and+cytoplasmic+domain+of+CTLA-4+synergistically+inhibited+T-cell+activation. assertion.
- assertion asSentence CTLA-4+%2B+49+A%2FG+and+CT60+gene+polymorphism+confers+genetic+susceptibility+to+type+1+diabetes%2C+particularly+in+patients+with+thyroid+autoimmunity. assertion.
- assertion asSentence Cytotoxic+T+lymphocyte-associated+antigen-4+polymorphism+in+patients+with+rheumatic+heart+disease. assertion.
- assertion asSentence CTLA-4+%2B49+A%3EG+polymorphism+is+associated+with+nasopharyngeal+carcinoma+susceptibility. assertion.
- assertion asSentence Plasma+sCTLA-4+is+associated+with+lung+function+and+-1147CT+polymorphism+in+Chinese+asthmatic+children. assertion.
- assertion asSentence There+is+a+cytotoxic+T+lymphocyte+antigen-4+%28CTLA-4%29+polymorphism+in+patients+with+Behcet%27s+disease. assertion.
- assertion asSentence The+frequency+of+GG+genotype+of+CTLA4+A49G+gene+polymorphism+in+Slovak+patients+with+rheumatoid+arthritis+is+not+significantly+higher+in+comparison+to+control+group. assertion.
- assertion asSentence Genetic+variation+in+the+CTLA-4+gene+is+associated+with+hepatic+cancer. assertion.
- assertion asSentence Cdc42+regulates+AJ+permeability+by+controlling+the+binding+of+alpha-catenin+with+beta-catenin+and+the+consequent+interaction+of+the+VE-cadherin%2Fcatenin+complex+with+the+actin+cytoskeleton. assertion.
- assertion asSentence Direct+attachment+of+alpha-catenin+to+F-actin+is+required+to+promote+cadherin-mediated+contact+formation+and+strong+cell-cell+adhesive+states. assertion.
- assertion asSentence An+evolutionarily+conserved+PTEN-C%2FEBPalpha-CTNNA1+axis+controls+myeloid+development+and+transformation. assertion.
- assertion asSentence CTNS+plays+a+pivotal+role+in+regulating+cell+thiol+concentrations. assertion.
- assertion asSentence Proof+for+the+regulated+phosphorylation+of+the+Ser%2FThr+residues+of+beta-catenin+by+Wnt+signaling. assertion.
- assertion asSentence Beta+catenin+induced+human+melanoma+growth+requires+the+downstream+target+Microphthalmia-associated+transcription+factor. assertion.
- assertion asSentence Presenilin+couples+beta-catenin+phosphorylation+through+two+sequential+kinase+activities+independent+of+the+Wnt-regulated+Axin%2FCK1alpha+complex. assertion.
- assertion asSentence CTNNB+is+ubiquinated+at+specific+lysines+by+the+F-box+protein+beta-TrCP1. assertion.
- assertion asSentence IpaC+interacts+with+beta-catenin+and+destabilizes+the+cadherin-mediated+cell+adhesion+complex. assertion.
- assertion asSentence A+functional+crosstalk+between+hepatocyte+growth+factor+receptor+%28MET%29+and+beta-catenin+signaling+sustains+and+increases+colorectal+carcinoma+cell+invasive+properties. assertion.
- assertion asSentence Beta-catenin+relieves+I-mfa-mediated+suppression+of+LEF-1+in+mammalian+cells. assertion.
- assertion asSentence The+Wnt%2Fbeta-catenin+signaling+transduction+pathway+is+activated+with+aberrant+expression+of+Wnt1+in+hepatocellular+carcinoma+cell+line+HepG2. assertion.
- assertion asSentence The+reciprocal+crosstalk+between+beta-catenin%2FTcf+pathway+and+NF-kappaB+signaling+in+hMSCs+is+mediated+through+the+regulation+of+lzts2+expression. assertion.
- assertion asSentence Beta-catenin+mutations+do+not+contribute+to+cardiac+fibroma+pathogenesis. assertion.
- assertion asSentence The+importance+of+beta-catenin+in+the+immortalization+process+of+HPCs%2C+from+its+dispensable+role+in+their+maintenance. assertion.
- assertion asSentence Correlation+between+beta-catenin+mutations+and+expression+of+Wnt-signaling+target+genes+in+hepatocellular+carcinoma. assertion.
- assertion asSentence Combination+treatment+of+As%282%29O%283%29+and+bortezomib+can+reduce+beta-catenin+level+in+myeloma+cell+lines. assertion.
- assertion asSentence Nuclear+beta-catenin+expression+correlating+with+the+grade+of+IEN+in+polyps+and+carcinomas+supports+its+role+in+colorectal+carcinogenesis. assertion.
- assertion asSentence There+is+a+functional+role+for+the+long+cytoplasmic+domain+of+CEACAM1+in+regulation+of+beta-catenin+activity. assertion.
- assertion asSentence Epigenetic+repression+of+DACT3+leads+to+aberrant+Wnt-beta-catenin+signaling+in+colorectal+cancer+cells. assertion.
- assertion asSentence Polycystin-1+C-terminal+tail+co-localizes+with+and+binds+to+beta-catenin+in+the+nucleus. assertion.
- assertion asSentence Snail+and+Slug+promote+formation+of+beta-catenin-T-cell+factor+%28TCF%29-4+transcription+complexes+that+bind+to+the+promoter+of+the+TGF-beta3+gene+to+increase+its+transcription. assertion.
- assertion asSentence Activation+of+the+canonical+Wingless+%28Wnt%29+signaling+pathway+by+a+stabilizing+mutation+of+beta-catenin+targeted+exclusively+to+thymic+epithelial+cells+changes+the+initial+commitment+of+endodermal+epithelia+to+a+thymic+cell+fate. assertion.
- assertion asSentence Both+dysplastic+and+nondysplastic+ACF+have+altered+beta-catenin+expression+and+play+a+role+in+colon+tumorigenesis. assertion.
- assertion asSentence Coexpression+of+HSP60+and+nuclear+beta-catenin+predicts+a+worse+prognosis+of+metastatic+head+and+neck+cancer+patients. assertion.
- assertion asSentence The+down-regulation+of+miR-122a+mediated+by+aberrant+APC%2Fbeta-catenin+signaling+is+important+to+the+pathogenesis+of+gastrointestinal+cancers. assertion.
- assertion asSentence Several+genetic+polymorphisms+in+beta-catenin+correlated+with+hepatitis+B+virus-related+hepatocellular+carcinoma. assertion.
- assertion asSentence A+direct+correlation+between+positive+Her2+expression+and+abnormal+beta-catenin+expression+exists+in+human+breast+carcinoma. assertion.
- assertion asSentence Dishevelled-KSRP+complex+operates+in+Wnt+regulation+of+beta-catenin%2C+functioning+post-transcriptionally+upon+CTNNB1+mRNA+stability. assertion.
- assertion asSentence A+minimal+promoter+for+intestinal+cell+kinase+contains+functional+sites+for+beta-catenin%2FTCF7L2+and+FOXA. assertion.
- assertion asSentence Periplocin+from+Cortex+periplocae+inhibits+cell+growth+and+down-regulates+survivin+and+c-myc+expression+in+colon+cancer+via+beta+catenin. assertion.
- assertion asSentence FoxM1+is+required+for+reannealing+of+endothelial+adherens+junctions+in+order+to+form+a+restrictive+endothelial+barrier+through+transcriptional+control+of+beta-catenin+expression. assertion.
- assertion asSentence Loss+of+membranous%2F+cytoplasmic+beta-catenin+expression+is+associated+with+invasion+in+diffuse-type+gastric+carcinomas. assertion.