Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence After+Reelin+binds+to+the+receptors%2C+Disabled-1+becomes+phosphorylated+on+tyrosine+residues%2C+initiating+a+signaling+cascade+that+includes+activation+of+Src-family+kinases+and+Akt. assertion.
- assertion asSentence DAB1+phosphorylation+occurs+solely+in+the+segment+spanning+the+5th+and+6th+reelin+repeats. assertion.
- assertion asSentence Dab1%2C+an+essential+component+of+the+reelin+pathway%2C+is+required+for+glia-independent+somal+translocation+in+the+neocortex. assertion.
- assertion asSentence Dab2+internalizes+integrins+freely+diffusing+on+the+cell+surface+and+Dab2+regulates+migration. assertion.
- assertion asSentence The+dachshund+is+required+in+mushroom+body+neurons+for+proper+axon+guidance+and+branching+in+Drosophila+melanogaster. assertion.
- assertion asSentence DACH1+is+hypermethylated+in+renal+cell+carcinoma. assertion.
- assertion asSentence DACH1+represses+gene+transcription+through+direct+DNA+binding+to+the+promoter+region+of+target+genes+by+recruiting+the+transcriptional+co-regulator%2C+TCERG1. assertion.
- assertion asSentence In+cells+growing+in+IGF-1+%28and+unresponsive+to+EGF%29%2C+DACH1+is+devoid+of+tumor+suppressor+activity. assertion.
- assertion asSentence Antigen-presenting+cell+exosomes+are+protected+from+complement-mediated+lysis+by+expression+of+CD55+and+CD59. assertion.
- assertion asSentence Protective+role+of+hDAF+in+pig+cells+to+heterologus+complement+mediated+damage+in+vitro. assertion.
- assertion asSentence Thrombin-induced+DAF+expression+involves+transactivation+of+PAR2+by+PAR1+and+signaling+via+PKC-epsilon%2FMAPK. assertion.
- assertion asSentence The+expression+of+CD55+is+down-regulated+in+hyperlipidemia+and+is+related+with+complement+activation. assertion.
- assertion asSentence Role+of+the+GPIIb%2FIIIa+inhibitor+tirofiban+for+the+prevention+of+hDAF+pig+heart+rejection+and+xenograft+function. assertion.
- assertion asSentence Neutralization+of+complement+regulatory+proteins+CD55+and+CD59+augments+therapeutic+effect+of+herceptin+against+lung+carcinoma+cells. assertion.
- assertion asSentence High+CD55+is+associated+with+aplastic+anemia. assertion.
- assertion asSentence Mumps+virus+%28MuV%29+and+vesicular+stomatitis+virus+%28VSV%29+assemble+to+include+CD46+and+CD55%2C+two+host+cell+regulators+which+inhibit+propagation+of+complement+pathways+through+distinct+mechanisms. assertion.
- assertion asSentence Defects+in+both+polymorphonuclear+neutrophil+%28PMN%29+transendothelial+migration+and+PMN+diacylglycerol+kinase+alpha+signaling+are+implicated+as+disordered+functions+in+subjects+with+localized+aggressive+periodontitis. assertion.
- assertion asSentence PPARgamma+agonists+upregulate+DGKalpha+production.This+suppresses+the+diacylglycerol%2Fprotein-kinase-C+signaling+pathway. assertion.
- assertion asSentence Diacylglycerol+kinase+gamma+regulates+macrophage+differentiation. assertion.
- assertion asSentence Some+support+for+the+individual+involvement+of+DAO+and+G72%28DAOA%29%2FG30+in+the+etiology+of+bipolar+disorder. assertion.
- assertion asSentence Expression+and+phosphorylation+of+DAP+kinase+in+hippocampus+of+patients+with+intractable+temporal+lobe+epilepsy+is+significantly+increased+compared+with+autopsy+controls. assertion.
- assertion asSentence The+promoter+hypermethylation+of+DAPK-1+is+a+marker+of+aggressive+renal+cell+carcinoma+and+provides+independent+prognostic+information+on+disease+outcome. assertion.
- assertion asSentence A+role+for+MAP1B+in+DAPK-1-dependent+signaling+in+autophagy+and+membrane+blebbing. assertion.
- assertion asSentence Loss+of+Med1+expression+directly+correlates+with+a+loss+of+dapk1+expression+in+a+number+of+human+lung+cancers+and+cancer+cell+lines. assertion.
- assertion asSentence Promoter+methylation+of+DAPK1%2C+E-cadherin+and+thrombospondin-1+in+de+novo+and+therapy-related+myeloid+neoplasms. assertion.
- assertion asSentence Variation+in+DAPK1+gene+influences+susceptibility+to+late-onset+Alzheimer%27s+disease+in+the+northern+Han+Chinese+population. assertion.
- assertion asSentence DAPK+negatively+regulates+Fas-mediated+apoptosis+in+these+human+differentiated+endometrial+adenocarcinoma+cells. assertion.
- assertion asSentence DAPK+mRNA+and+protein+expression+levels+are+association+with+DAPK+promoter+methylation+in+gastric+cancer+tissues+of+patients+from+central+China. assertion.
- assertion asSentence Sodium+butyrate+induced+DAPK1%2F2+expression+in+human+gastric+cancer+cells+and+this+expression+prompted+apoptosis+by+decreasing+FAK+levels. assertion.
- assertion asSentence Dlk+plays+a+positive+role+in+modulating+death-related+signaling+pathways. assertion.
- assertion asSentence Reorganization+of+the+PML+nuclear+body+by+E4+ORF3+antagonizes+an+innate+antiviral+response+mediated+by+both+PML+and+Daxx. assertion.
- assertion asSentence Neither+Daxx+nor+PML%2C+the+main+players+of+ND10-based+immunity%2C+are+required+for+the+block+to+viral+gene+expression+in+the+S%2FG2+phase. assertion.
- assertion asSentence DAZ%2FDAZL+protein+can+form+a+stable+complex+with+human+PUM2. assertion.
- assertion asSentence DAZ+activates+translationally+silent+mRNAs+during+germ+cell+development+through+the+direct+recruitment+of+polyA-binding+proteins. assertion.
- assertion asSentence PUM2+and+DAZL%2C+are+capable+of+binding+the+same+mRNA+sequences+in+the+3%27UTR+of+human+SDAD1+mRNA. assertion.
- assertion asSentence The+prevalent+inactivation+of+DBCCR1+seen+at+the+expression+level+in+astrocytomas+is+not+primarily+caused+by+genomic+loss+of+the+gene. assertion.
- assertion asSentence Norepinephrine+deficiency+is+caused+by+combined+abnormal+mRNA+processing+and+defective+protein+trafficking+of+dopamine+beta-hydroxylase. assertion.
- assertion asSentence DCC+binds+netrin+through+the+fourth+fibronectin+type+III+domain. assertion.
- assertion asSentence DCC+expression+appears+not+to+be+predictive+in+poor+survival+outcome+in+patients+with+stage+II+or+III+colorectal+cancer. assertion.
- assertion asSentence Lost+expression+of+DCC+gene+is+associated+with+ovarian+cancer. assertion.
- assertion asSentence Sensitivity+of+two+pancreatic+cancer+cell+lines+transduced+with+deoxycytidine+kinase+to+gemcitabine+elevated+dramatically+in+comparison+with+control+cells. assertion.
- assertion asSentence Altered+expression+of+decorin+mRNA+in+the+different+dermal+strata+and+a+decrease+in+the+collagen-to-decorin+ratio+inflicted+by+both+age+and+ultraviolet+irradiation+affect+collagen+bundle+diameter+and+subsequently+the+mechanical+properties+of+human+skin. assertion.
- assertion asSentence KRAS+mutations+correlate+with+expression+of+DCN+and+TPM1+in+colorectal+cancer. assertion.
- assertion asSentence Postinfarction+gene+therapy+with+adenoviral+vector+expressing+decorin+mitigates+cardiac+remodeling+and+dysfunction. assertion.
- assertion asSentence DCN+is+a+negative+regulatory+protein+inhibiting+hepatoma+carcinoma+cell+proliferation+through+inhibiting+cell+cycle+and+inducing+apoptosis. assertion.
- assertion asSentence Nuclear+localized+decorin+plays+an+important+role+in+migration+and+invasion+of+oral+cancer+cells. assertion.
- assertion asSentence During+shedding+of+the+ectodomain+of+ACE%2C+a+minimum+requirement+is+an+exposed+or+unhindered+sequence+of+minimum+length+between+the+extracellular+domain+and+the+membrane%2C+within+or+adjacent+to+otherwise+compact%2C+folded+domains. assertion.
- assertion asSentence ACE+insertion%2Fdeletion+polymorphism+and+submaximal+exercise+cardiovascular+hemodynamics+in+postmenopausal+women. assertion.
- assertion asSentence ACE+polymorphism+is+not+a+risk+factor+for+the+development+of+cerebral+infarction+in+a+Korean+population. assertion.
- assertion asSentence Angiotensin+I-converting+enzyme+and+metabolism+of+the+haematological+peptide+N-acetyl-seryl-aspartyl-lysyl-proline. assertion.
- assertion asSentence Increased+risk+of+systemic+sclerosis+in+ACE+D+allele+carriers. assertion.
- assertion asSentence ACE+I%2FD+polymorphism+is+not+a+significant+risk+factor+for+peripheral+arterial+disease. assertion.
- assertion asSentence Patients+with+Mitral+valve+prolapse+syndrome+have+a+higher+frequency+of+ACE+II+genotype. assertion.
- assertion asSentence Plasma+levels+of+ET-1%2C+ACE+activities+are+elevated+and+associated+with+reduction+of+GH%2C+NO+and+cGMP+levels+in+the+systemic+and+cavernous+blood+of+erectile+dysfunction+patients. assertion.
- assertion asSentence The+DD+genotype+of+the+ACE+gene+impairs+the+coronary+release+of+tissue+plasminogen+activator+induced+by+bradykinin. assertion.
- assertion asSentence ACE+gene+polymorphism+has+a+higher+risk+of+disease+progression+in+patients+with+hypertrophic+cardiomyopathy. assertion.
- assertion asSentence Polymorphic+markers+of+ACE+candidate+genes+influence+clinical+diversity+of+pathological+signs+in+DM2+patients+through+modification+of+AH+and+LVH+severity. assertion.
- assertion asSentence There+is+an+association+between+the+ACE+I%2FD+common+gene+variant+and+Type+2+Diabetes+Mellitus. assertion.
- assertion asSentence There+is+a+genetic+predisposition+for+the+pulmonary+complications+following+esophagectomy+for+esophageal+cancer. assertion.
- assertion asSentence Carriage+of+the+D+allele+of+the+ACE+gene+is+a+strong%2C+independent+risk+factor+for+excess+weight+gain+after+liver+transplantation. assertion.
- assertion asSentence No+influence+of+the+ACE+gene+polymorphism+in+chronic+allograft+nephropathy. assertion.
- assertion asSentence Insertion%2Fdeletion+polymorphism+in+angiotensin-converting+enzyme+gene+does+not+play+role+in+pathogenesis+of+pseudoexfoliation. assertion.
- assertion asSentence Angiotensin-converting+enzyme+insertion%2Fdeletion+polymorphism+ACE+I%2FD+associated+between+TT+genotype+and+hypertension. assertion.
- assertion asSentence No+association+between+ACE1+gene+polymorphism+and+the+progression+rate+of+focal+segmental+glomerulosclerosis+in+Iranian+children. assertion.
- assertion asSentence The+D+allele+of+the+ACE+gene+is+associated+with+essential+hypertension+and+type+2+diabetes+mellitus+in+Malaysian+subjects. assertion.
- assertion asSentence Single-nucleotide+polymorphisms+in+the+ACE+gene+is+associated+with+progression+of+carotid+atherosclerosis. assertion.
- assertion asSentence Demonstrate+an+association+between+eNOS+and+ACE+genes+in+increasing+peripheral+arterial+disease+susceptibility+in+smokers. assertion.
- assertion asSentence QT+dispersion+and+corrected+QT+dispersion+are+increased+in+patients+with+HCM%2C+especially+in+those+with+the+DD+genotype. assertion.
- assertion asSentence Significant+differences+between+rugby+forwards+and+backs+relative+to+ACE+ID+and+DD+genotypes+in+leg+power. assertion.
- assertion asSentence Somatic+angiotensin-converting+enzyme+gene+expression+is+influenced+by+epigenetic+modification. assertion.
- assertion asSentence Besides+angiotensin+II%2C+ACE+regulates+a+panel+of+bioactive+peptides%2C+such+as+substance+P%2C+antifibrotic+peptide+Ac-SDKP+and+angiotensin+1-7%2C+all+of+which+orchestrate+the+pathways+of+hematopoiesis. assertion.
- assertion asSentence D-allele+of+ACE+gene+is+an+erectile+dysfunction+risk+factor+in+males+with+metabolic+syndrome. assertion.
- assertion asSentence The+common+ACE+deletion+polymorphism+is+associated+with+a+greater+than+2-fold+increase+in+the+odds+of+developing+JET+in+children+undergoing+surgical+repair+of+congenital+heart+defects. assertion.
- assertion asSentence ACE+deletions+are+the+most+frequent+genetic+variants+in+risk+groups+of+dyslipidemic+patients+%28from+58%25+in+cardiovascular+events+to+51%25+in+smokers%29. assertion.
- assertion asSentence A+synergistic+effect+between+ACE+insertion%2Fdeletion+polymorphism+with+either+MTHFR+C677T+or+A1298C+polymorphism+on+the+increased+risk+of+diabetic+nephropathy+among+patients+with+type+2+diabetes+mellitus. assertion.
- assertion asSentence ACE+I%2FD+is+not+an+independent+risk+factor+for+severe+carotid+atherosclerosis. assertion.
- assertion asSentence ACE+D+allele+or+DD+homozygosity+is+associated+with+the+end-stage+renal+disease+susceptibility+in+diabetic+nephropathy+patients. assertion.
- assertion asSentence D+allele+and+DD+ACE+genotype+are+risk+factors+for+the+vesicoureteral+reflux+susceptibility%2Frenal+scar+in+Turkish+children. assertion.
- assertion asSentence Trp2+SNP2+allele+is+a+risk+factor+for+the+development+and+severity+of+degenerative+disc+disease+in+a+Chinese+Han+population. assertion.
- assertion asSentence The+function+of+p150%28Glued%29+in+membrane+trafficking+is+not+associated+with+plus-end+localization. assertion.
- assertion asSentence Par6alpha+controls+centrosome+organization+through+its+association+with+the+dynactin+subunit+p150%28Glued%29. assertion.
- assertion asSentence End-binding+proteins+interact+with+the+CAP-Gly+domains+of+CLIP-170+and+p150%28glued%29. assertion.
- assertion asSentence Doublecortin+is+applicable+for+the+detection+of+individual+infiltrating+glioma+cells+when+combined+with+other+markers. assertion.
- assertion asSentence The+DCX+binding+on+the+microtubules+surface+indirectly+stabilizes+conserved+tubulin-tubulin+lateral+contacts+in+the+microtubules+lumen%2C+operating+independently+of+the+nucleotide+bound+to+tubulin. assertion.
- assertion asSentence SV5-V+and+HBx+have+evolved+to+bind+DDB1+to+achieve+distinct+functions+in+their+life+cycle%2C+both+by+a+mechanism+that+does+not+involve+DDB2. assertion.
- assertion asSentence Damaged+DNA+binding+protein+1+is+a+component+of+the+centromere+complex+in+interphase+cells. assertion.
- assertion asSentence PCNA+is+involved+in+mediating+Cdt1+degradation+by+the+Cul4-Ddb1+ligase+in+response+to+DNA+damage. assertion.
- assertion asSentence Monoubiquitinated+histone+H2A+in+native+chromatin+coimmunoprecipitates+with+the+endogenous+DDB1-CUL4A%28DDB2%29+complex+in+response+to+UV+irradiation. assertion.
- assertion asSentence CUL4-DDB1+ubiquitin+ligase+interacts+with+Raptor+and+regulates+the+mTORC1-mediated+signaling+pathway+through+ubiquitin-dependent+proteolysis. assertion.
- assertion asSentence CUL-4A+mediates+the+proteolytic+degradation+of+DDB2+and+this+degradation+event%2C+initiated+at+the+lesion+sites%2C+regulates+damage+recognition+by+XPC. assertion.
- assertion asSentence DDB2+exerts%2C+at+least+in+part%2C+a+control+of+breast+cancer+cell+growth+through+its+negative+regulation+of+constitutive+expression+of+the+SOD2+gene. assertion.
- assertion asSentence p53+is+primarily+protective+against+ultraviolet+rays-induced+apoptosis+in+primary+human+fibroblasts+and+this+activity+of+p53+does+not+require+DDB2. assertion.
- assertion asSentence Overexpression+of+DDB2+enhances+the+sensitivity+of+ovarian+cancer+cells+to+cisplatin+by+augmenting+cellular+apoptosis. assertion.
- assertion asSentence Early+induction+of+CDKN1A+%28p21%29+and+GADD45+mRNA+by+a+low+dose+of+ionizing+radiation+is+due+to+their+dose-dependent+post-transcriptional+regulation. assertion.
- assertion asSentence Gadd45a-deficient+human+colon+cancer+cells+exhibited+slow+base+excision+repair+after+treatment+with+methyl+methanesulfonate%2C+a+pure+base-damaging+agent. assertion.
- assertion asSentence Gadd45a+stress+signaling+regulates+sFlt-1+expression+in+preeclampsia. assertion.
- assertion asSentence Estrogen+receptor+beta+causes+a+G2+cell+cycle+arrest+by+inactivating+CDK1+through+the+repression+of+cyclin+B1+and+stimulation+of+GADD45A+and+BTG2+expression. assertion.
- assertion asSentence Oil+A+induces+apoptosis+of+pancreatic+cancer+cells+via+activating+caspase+cascade%2C+modifying+cell+cycle+progress+and+changing+cell+cycle-regulating+proteins+and+GADD+expression. assertion.
- assertion asSentence Effect+of+FUS-DDIT3+fusion+on+IL6+expression+is+C%2FEBP+beta+dependent+in+myxoid+lipoxarcoma. assertion.
- assertion asSentence A+switch+between+C%2Fenhancer-binding+protein+%28CEBP%29+zeta+and+CEBP+beta+operates+at+the+CEBP+site+on+the+C-reactive+protein+%28CRP%29promoter+to+regulate+CRP+transcription. assertion.