Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence EGFR+mutations+are+associated+with+docetaxel+response+in+lung+cancer. assertion.
- assertion asSentence EGFR+mutations+are+associated+with+response+to+therapy+in+lung+adenocarcinoma. assertion.
- assertion asSentence Shigella+flexneri+infection+generates+the+lipid+PI5P+to+alter+endocytosis+and+prevent+termination+of+EGFR+signaling. assertion.
- assertion asSentence EGFR+mutations+are+associated+with+non-small+cell+lung+cancer. assertion.
- assertion asSentence Suppressing+expression+of+EGFR+inhibited+cell+proliferation. assertion.
- assertion asSentence The+epidermal+growth+factor+receptor+%28EGFR%29+is+over-expressed+in+40-80%25+of+patients+with+non-small-cell+lung+cancer+%28NSCLC%29. assertion.
- assertion asSentence High+EGFR+expression+is+a+tumour+biomarker+that+can+predict+survival+benefit+from+the+addition+of+cetuximab+to+first-line+chemotherapy+in+patients+with+advanced+non-small+lung+cancer. assertion.
- assertion asSentence Cathepsin+S+plays+an+important+role+in+the+regulation+of+cell+autophagy+through+interference+with+the+EGFR-ERK%2FMAPK-signaling+pathway. assertion.
- assertion asSentence EGFR+plays+a+critical+role+in+mediating+nontypeable+Haemophilus+influenzae+-induced+NF-kappaB+activation+and+inflammation. assertion.
- assertion asSentence EGFR+mutation+status+is+associated+with+lung+adenocarcinoma. assertion.
- assertion asSentence Lack+of+EGFR+mutations+is+associated+with+gefitinib+treatment+response+in+adenocarcinoma+of+esophagogastric+junction. assertion.
- assertion asSentence In+HER1%2C+the+extracellular+region+asymmetry+requires+interactions+with+the+plasma+membrane. assertion.
- assertion asSentence Hedgehog-EGFR+regulated+genes%2C+SOX2%2C+SOX9%2C+JUN%2C+CXCR4+and+FGF19%2C+are+required+for+tumor+growth. assertion.
- assertion asSentence EGFR+mutations+are+more+frequent+in+female+patients+and+patients+with+adenocarcinoma+NSCLC%2C+involving+mainly+exon+19+and+21. assertion.
- assertion asSentence EGF-mediated+CYR61+upregulation+in+HES+cells+involves+STAT3+and+is+counter-regulated+by+the+EGFR%2FMAPK%2FERK+pathway. assertion.
- assertion asSentence EGFR+somatic+mutations+are+rare+in+pancreatobiliary+malignancies. assertion.
- assertion asSentence Increasing+knowledge+of+EGFR+biology+is+driving+more+targeted+or+alternative+approaches+to+cancer+therapies. assertion.
- assertion asSentence Loss+of+the+ceramide+transfer+protein+augments+EGF+receptor+signaling+in+breast+cancer. assertion.
- assertion asSentence The+TERT-CLPTM1L+locus+influences+melanoma+risk. assertion.
- assertion asSentence Human+telomerase+represses+ROS-dependent+intracellular+signaling+and+gene+induction. assertion.
- assertion asSentence A+series+of+mutations+in+the+carbonate-binding+threonine+and+arginine+residues+of+the+N-terminal+and+C-terminal+lobes+of+full-length+transferrin+%28and+in+the+N-lobe+by+itself%29+substantially+alters+the+synergistic+anion-binding+functions+of+transferrin. assertion.
- assertion asSentence Apotransferrin+can+influence+oligodendroglia+gene+expression+and+differentiation+through+multiple+mechanisms+depending+on+the+maturation+of+the+cell. assertion.
- assertion asSentence The+combination+of+the+C2+allele+of+transferrin+and+the+C282Y+allele+of+the+haemochromatosis+gene+increase+susceptibility+for+developing+Alzheimer%27s+disease. assertion.
- assertion asSentence Increased+levels+in+urine+predicts+development+of+microalbuminuria+in+type+2+diabetes. assertion.
- assertion asSentence Human+TF+expression+by+both+hematopoietic+and+nonhematopoietic+mouse+cells+contributes+to+activation+of+coagulation+in+mice+8+hours+after+LPS+administration. assertion.
- assertion asSentence Missense+polymorphisms+rs1049296+and+rs1799899+in+TF+strongly+affecting+transferrin+glycosylation. assertion.
- assertion asSentence Gene+diversity+for+haptoglobin+and+transferrin+classical+markers+among+Hindu+and+Muslim+populations+of+Aligarh+City%2C+India. assertion.
- assertion asSentence Retinal+function+and+gene+expression+of+some+of+the+iron-associated+genes+are+significantly+altered. assertion.
- assertion asSentence Transferrin-binding+protein+B+stabilizes+the+holo+form+of+human+transferrin. assertion.
- assertion asSentence BfrA%2C+BfrD+and+BfrE+are+catecholamine+receptors+and+are+involved+in+the+utilization+of+iron+liberated+from+transferrin+by+host+catecholamine+stress+hormones. assertion.
- assertion asSentence Three+polymorphisms+in+the+TFAM+gene+rs1937%2C+rs2306604+and+rs1049432+do+not+predict+endurance+capacity%2Ftrainability+in+Chinese+males. assertion.
- assertion asSentence TFAM+gene+Ser12Thr+polymorphism+is+associated+with+physical+performance+of+athletes. assertion.
- assertion asSentence TFAM-deficient+fibroblasts+promote+breast+cancer+tumor+growth+in+vivo%2C+without+increasing+tumor+angiogenesis. assertion.
- assertion asSentence AP2alpha+suppresses+C%2FEBPalpha+promoter+activity+and+protein+expression+in+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence TFAP2A+binds+to+two+regions+of+the+promoter+of+CDKN1A+and+alters+with+time+post-induction%2C+with+the+proximal%2C+p53-independent+site+becoming+more+important+at+later+stages+of+p21cip+induction. assertion.
- assertion asSentence AP-2beta+intron+2+genotype+is+associated+with+low+levels+of+anxiety-related+personality+traits+in+women. assertion.
- assertion asSentence No+association+between+the+AP-2beta+genotype+and+measures+of+dopamine+receptor+density%2C+or+CSF+5-HIAA+concentrations. assertion.
- assertion asSentence Genetic+variations+in+the+gene+encoding+TFAP2B+are+associated+with+type+2+diabetes+mellitus. assertion.
- assertion asSentence TFAP2B%2C+LYPLAL1+and+MSRA+are+associated+with+adiposity+and+fat+distribution. assertion.
- assertion asSentence Loss+of+TFAP2B+is+associated+with+retinoblastoma. assertion.
- assertion asSentence It+causes+accumulation+of+neutral+fats+and+causes+insulin+resistance+through+exaggerated+glucose+uptake+independent+of+insulin+and+induces+abnormal+adipokine+secretion%2C+fat+cell+enlargement+and+insulin+resistance. assertion.
- assertion asSentence Overexpression+of+TFAP2C+is+associated+with+hormone+responsive+breast+carcinoma. assertion.
- assertion asSentence C-MYC+directly+regulates+the+expression+of+AP4+via+CACGTG+motifs+in+the+first+intron+of+the+AP4+gene. assertion.
- assertion asSentence Regulation+of+retinoic+acid-induced+inhibition+of+AP-1+activity+by+orphan+receptor+chicken+ovalbumin+upstream+promoter-transcription+factor. assertion.
- assertion asSentence A+chicken+ovalbumin+upstream+promoter+transcription+factor+I+%28COUP-TFI%29+complex+represses+expression+of+the+gene+encoding+tumor+necrosis+factor+alpha-induced+protein+8+%28TNFAIP8%29. assertion.
- assertion asSentence NR2F2+plays+a+crucial+role+in+the+activation+of+neural+genes+during+early+differentiation+in+humans. assertion.
- assertion asSentence MITF+and+TFE3+reciprocally+rescue+one+another+in+lines+derived+from+CCS+or+pediatric+renal+carcinoma. assertion.
- assertion asSentence TFF1+and+Cdc25A-B+cooperate+with+other+dominant+oncogenic+pathways+to+induce+the+adenoma+and+adenocarcinoma+transitions. assertion.
- assertion asSentence TFF3+has+important+physiological+functions+in+the+stomach%2C+e.g.+as+a+luminal+surveillance+peptide+maintaining+particularly+the+integrity+of+the+antral+and+pyloric+mucosa. assertion.
- assertion asSentence The+expression+of+TFF3+in+chronic+graft-versus-host+disease+of+the+liver+is+increased+in+response+to+bile+duct+damage+and+repair. assertion.
- assertion asSentence Immobilized+rTFPI+slows+fibrin+deposition+on+vascular+graft+material+by+inhibiting+contact+pathway+and+blood+borne+tissue+factor+procoagulant+arising+from+either+alternatively+spliced+form+of+tissue+factor+or+from+tissue+factor+containing+microparticles. assertion.
- assertion asSentence Immunoglobulin+G+fractions+from+subjects+with+antiphospholipid+syndrome+have+inhibitory+activity+against+tissue+factor+pathway+inhibitor+%28TFPI%29. assertion.
- assertion asSentence Elevated+levels+of+TF+and+TFPI+in+patients+with+peripheral+arterial+occlusive+disease+can+be+independent+risk+factor+for+atherosclerotic+complications. assertion.
- assertion asSentence Therapeutic+rh-TFPI+attenuates+coagulation%2C+inflammation+and+bacterial+growth+during+pneumococcal+pneumonia. assertion.
- assertion asSentence Transferrin+receptor+2+mediates+transferrin-bound+iron+uptake+by+receptor-mediated+endocytosis. assertion.
- assertion asSentence MtF+expression+is+downregulated+during+ATRA-induced+K562+cell+differentiation%2C+with+concomitant+downregulation+of+TfR1+and+upregulation+of+Fn. assertion.
- assertion asSentence PCSK7+is+involved+in+sTfR+generation+and+iron+homeostasis. assertion.
- assertion asSentence Clinical+value+of+a+differential+response+of+thyroglobulin+%28Tg%29+concentration+after+recombinant+human+thyrotropin+in+thyroid+paxpillary+adenocarcinoma+after+thyroidectomy. assertion.
- assertion asSentence Patients+with+detectable+Tg+during+the+last+%281%29%283%29%281%29I+treatment+and+a+negative+post-therapeutic+WBS+have+significant+earlier+and+more+recurrences+than+patients+without+detectable+Tg. assertion.
- assertion asSentence In+patients+with+well-differentiated+thyroid+cancer%2C+a+post-thyroidectomy+thyroglobulin+level+less+than+10+ng%2Fml+is+associated+with+a+low+probability+of+having+persistent+disease. assertion.
- assertion asSentence Papillary+thyroid+carcinoma+patients+assessed+to+be+at+low+or+intermediary+risk+after+primary+treatment+are+at+greater+risk+of+long+term+recurrence+if+they+are+thyroglobulin+antibody+positive+or+do+not+have+low+thyroglobulin+at+initial+assessment. assertion.
- assertion asSentence Cold+exposure+influences+thyroid+hormones+and+TG+activity+in+serum+in+Arctic+populations+consistent+with+consumption+of+thyroid+hormone+and+higher+thyroid+hormone+turnover. assertion.
- assertion asSentence Epistasis+between+the+HSD17B4+and+thyroglobulin+polymorphisms+is+associated+with+premature+ovarian+failure. assertion.
- assertion asSentence Autocrine+TGF-alpha+functions+by+facilitating+re-entry+into+the+cell+cycle+from+sub-optimal+growth+states+rather+than+promoting+or+controlling+the+proliferation+of+actively+cycling+cells. assertion.
- assertion asSentence Rapamycin+prevents+transforming+growth+factor-alpha-induced+pulmonary+fibrosis. assertion.
- assertion asSentence TGFA%2FEGFR+signaling+contributes+to+the+proliferation+of+papillary+thyroid+carcinomas+cells. assertion.
- assertion asSentence TGF-beta+1+in+combination+with+IL-13+increases+production+of+eotaxin-1+in+airway+fibroblasts+from+asthmatic+and+normal+subjects. assertion.
- assertion asSentence TGF-beta1+up-regulates+expression+of+integrins+and+fibronectin%2C+an+effect+that+is+associated+with+autophosphorylation%2Factivation+of+focal+adhesion+kinase. assertion.
- assertion asSentence Dysregulation+of+TGF-beta+activation+contributes+to+pathogenesis+in+Marfan+syndrome. assertion.
- assertion asSentence An+increased+concentration+of+wild-type+GFAT+in+mesangial+cells+is+enhanced+both+TGF-beta1+and+fibronectin. assertion.
- assertion asSentence Stimulation+of+vascular+endothelial+cells+with+TGF-beta1+induced+marked+increase+in+the+expression+level+of+HAS2+mRNA+and+protein. assertion.
- assertion asSentence Endothelial+cell+vessel+assembly+requires+TGFB1+signaling+transduction+pathways. assertion.
- assertion asSentence The+TGFB1+T%2B869C+%28Leu10Pro%29+gene+polymorphism+is+associated+with+multiple+sclerosis+susceptibility%2C+especially+in+males. assertion.
- assertion asSentence The+high+expressions+of+TGF-beta1+and+TGFbR1+play+important+roles+in+spontaneous+abortion. assertion.
- assertion asSentence TFG-beta+is+an+inducer+of+gremlin+expression+in+diabetic+nephropathy. assertion.
- assertion asSentence PU.1+and+Id2+modulate+lineage+options+of+langerhans+cell+precursors%2C+downstream+of+TGF-beta1. assertion.
- assertion asSentence TGF-beta1+mRNA+levels+distinguish+chronic+allograft+nephropathy+patients+from+long-term+transplant+patients+with+stable+renal+function+and+varied+levels+of+proteinuria. assertion.
- assertion asSentence C-Fos+binding+at+the+TGFbeta1+promoter+proximal+AP-1+site+in+human+colon+carcinoma+cells+is+required+for+TGFbeta1+production+by+the+tumor+cells. assertion.
- assertion asSentence Supernatants+from+HPV-transformed+cell+cultures+contained+IL-10+and+TGF-+beta1. assertion.
- assertion asSentence TGF-beta1%2C+together+with+Notch+signaling%2C+functions+to+arrest+epithelial+growth. assertion.
- assertion asSentence TGFbeta+promotes+conversion+of+CD16%2B+peripheral+blood+NK+cells+into+CD16-+NK+cells+with+similarities+to+decidual+NK+cells. assertion.
- assertion asSentence TGF-beta+reduces+interferon-gamma-induced+major+histocompatibility+complex+%28MHC%29+class+II+expression+in+mesenchymal+stromal+cells+via+serum+factor+and+cell+density+effects+on+transactivator+CIITA+expression. assertion.
- assertion asSentence Gastrointestinal+carcinoid+tumor+fibrosis+is+a+CTGF%2FTGFbeta1-mediated+stellate+cell-driven+fibrotic+response. assertion.
- assertion asSentence Integration+of+TGFB+and+RAS+signaling+silences+RABGEF1+and+enhances+growth+factor-directed+cell+migration. assertion.
- assertion asSentence TGF-beta1%2FTNF-alpha+levels+and+endothelial+cell+activation+are+interrelated+in+kidney+transplant+patients. assertion.
- assertion asSentence Integrin+alphavbeta6+is+strongly+up-regulated+in+proliferating+bile+duct+epithelia+and+drives+fibrogenesis+via+adhesion+to+fibronectin+and+auto%2Fparacrine+TGF-beta1+activation. assertion.
- assertion asSentence EGF+contributes+to+differentiation+and+migration+of+myofibroblasts+induced+by+TGF-beta1+through+EGF-receptor+activation+and+is+important+modulator+of+wound+healing+and+scar+tissue+formation. assertion.
- assertion asSentence Erythromycin+A+and+EM703+inhibit+TGF-beta+signaling+in+human+lung+fibroblasts+via+inhibition+of+p-Smad2%2F3+through+recovery+of+Smad7+level. assertion.
- assertion asSentence TGF-beta1+single+nucleotide+polymorphisms+are+not+significantly+associated+with+increased+risk+of+chronic+allograft+nephropathy+and+graft+survival+in+Korean+renal+transplant+recipients. assertion.
- assertion asSentence The+expression+of+TGF-beta+occurs+in+both+granulosa+cells+and+thecal+cells+throughout+antral+follicle+development. assertion.
- assertion asSentence TGF-beta1+promotes+vascular+invasion+in+hepatocellular+carcinomas+by+activating+beta1+integrin. assertion.
- assertion asSentence Combination+of+CTLA-4+and+TGFbeta1+polymorphisms+is+associated+with+the+susceptibility+of+DHF+and+higher+virus+load. assertion.
- assertion asSentence There+is+disregulation+in+expression+of+the+TGFB1+gene+and+its+receptors+as+well+during+isolated+Raynaud+phenomenon+as+in+systemic+sclerosis. assertion.
- assertion asSentence Losartan+can+reverse+left+ventricular+hypertrophy+in+elderly+patients+with+essential+hypertension+partially+by+lowering+plasma+TGF-beta1+level. assertion.
- assertion asSentence Three-dimensional+culture+using+a+radial+flow+bioreactor+induces+matrix+metalloprotease+7-mediated+EMT-like+process+in+tumor+cells+via+TGFbeta1%2FSmad+pathway. assertion.
- assertion asSentence Suppression+of+TNF-alpha+on+TGF-beta-induced+CTGF+expression+is+due+to+the+competition+of+p300+by+p65+and+Smad4. assertion.
- assertion asSentence Pleural+mesothelial+cells+activated+by+TGF-beta1+undergo+epithelial-mesenchymal+transition+%28EMT%29+and+respond+with+haptotactic+migration. assertion.
- assertion asSentence PAI-1-mediated+regulation+of+alphavbeta3+integrin+is+critical+for+the+control+of+TGFbeta+signaling+and+the+prevention+of+fibrotic+disease. assertion.
- assertion asSentence TGFbeta+stimulates+Bim+transcription+by+up-regulating+the+expression+of+the+transcription+factor+Runx1+through+an+internal+ribosome+entry+site+-dependent+mechanism. assertion.
- assertion asSentence Circulating+TGFB1+is+a+reliable+biomarker+for+chronic+kidney+disease+progression+in+the+African-American+population. assertion.