Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+interactions+between+the+TLR3+ectodomain+and+double-stranded+RNA+depended+on+acidic+pH. assertion.
- assertion asSentence Dimer+of+TLR3+is+the+form+that+binds+RNA+and+activates+signal+transduction. assertion.
- assertion asSentence TLR3+has+a+major+role+in+the+development+of+ARDS-like+pathology+in+the+absence+of+a+viral+pathogen. assertion.
- assertion asSentence Toll-like+receptors+3+highly+expressed+on+human+melanoma+cells. assertion.
- assertion asSentence Cultured+human+melanocytes+express+functional+toll-like+receptors+2-4%2C+7+and+9. assertion.
- assertion asSentence TLR3+or+TLR7+ligand+stimulation+of+tumor+cells+enhances+the+cytotoxic+activity+of+expanded+gammadelta+T+cells+of+cancer+patients+in+vitro. assertion.
- assertion asSentence The+binding+of+TRAF2+and+TRAF6+to+TICAM-1+cooperatively+activates+the+IFN-inducing+pathway+through+ubiquitination+of+TICAM-1. assertion.
- assertion asSentence Unexpected+protective+role+for+Toll-like+receptor+3+in+the+arterial+wall. assertion.
- assertion asSentence Synergy+between+TLR3+and+IL-18+promotes+IFN-gamma+dependent+TRAIL+expression+in+liver+NK+cells. assertion.
- assertion asSentence The+Toll-like+receptor+%28TLR%293%2FTICAM-1+pathway+governs+type+I+interferon+induction+and+protection+against+poliovirus+%28PV%29infection+in+PV+receptor-bearing+transgenic+mice. assertion.
- assertion asSentence Toll-like+receptor+3+%28TLR3%29+recognizes+dsRNA+and+initiates+an+innate+immune+response+through+the+formation+of+a+signaling+unit+%28SU%29+composed+of+one+double-stranded+RNA+%28dsRNA%29+and+two+TLR3+molecules. assertion.
- assertion asSentence Polymorphisms+in+toll-like+receptor+4+are+not+associated+with+asthma+or+atopy-related+phenotypes. assertion.
- assertion asSentence Polymorphism+is+associated+with+systemic+inflammatory+response+syndrome. assertion.
- assertion asSentence Hepatocytes+utilize+components+of+TLR4+signal+transduction+pathways+in+response+to+lipopolysaccharide. assertion.
- assertion asSentence TLR4+SNPs+are+associated+with+resistance+to+Legionnaires%27+disease. assertion.
- assertion asSentence TLR4-mediated+responses+to+malaria+in+vivo+and+TLR-4+polymorphisms+are+associated+with+disease+manifestation. assertion.
- assertion asSentence Pathogen+recognition+receptor+TLR4+is+involved+in+activation+of+immature+monocyte-derived+dendritic+cells+by+the+envelope+protein+surface+unit+%28ENV-SU%29+of+multiple+sclerosis-associated+retroviral+element+%28MSRV%29+of+human+endogenous+retrovirus. assertion.
- assertion asSentence RANTES+down-regulates+TLR4+ligation-induced+IL-6+and+TNF-alpha+secretion+by+enhancing+IL-10+production+in+PB+monocytes. assertion.
- assertion asSentence LPS+can+up-regulate+TLR4+mRNA+and+protein+expression+in+human+aortic+smooth+muscle+cells+in+dose-+and+time-dependent+manner. assertion.
- assertion asSentence Platelet+TLR4+activates+neutrophil+extracellular+traps+to+ensnare+bacteria+in+septic+blood. assertion.
- assertion asSentence TLR4+%28896A%3EG%29+mutations+are+associated+with+the+infection+of+pancreatic+necrosis+in+the+patients+with+AP. assertion.
- assertion asSentence TLR-4+gene+polymorphisms+are+associated+with+lower+levels+of+P-selectin+and+von+Willebrand+factor+among+hypercholesterolemic+patients. assertion.
- assertion asSentence In+human+neutrophils%2C+Helicobacter+pylori+induces+an+early+inflammatory+response%2C+partially+mediated+via+TLR2+and+TLR4+activation. assertion.
- assertion asSentence Murine+beta-defensin+2+%28mDF2beta%29+can+act+as+an+endogenous+ligand+for+TLR-4-activating+maturation+of+dendritic+cells. assertion.
- assertion asSentence TLR-4+signaling+in+small+intestinal+epithelium+promotes+B-cell+recruitment+and+IgA+production+in+lamina+propria. assertion.
- assertion asSentence Interaction+between+TLR4+expression+and+the+pathogenesis+of+chronic+hepatitis+B. assertion.
- assertion asSentence Estradiol+regulates+MICA+expression+in+human+endometrial+cells. assertion.
- assertion asSentence Respiratory+syncytial+virus+induced+epithelial+TLR4+up-regulation. assertion.
- assertion asSentence Toll-like+receptors+4+highly+expressed+on+human+melanoma+cells. assertion.
- assertion asSentence The+leucine+at+position+815+is+required+for+the+normal+maturation+of+TLR4+and+for+formation+of+the+TLR4.MD-2+complex. assertion.
- assertion asSentence TLR4+single+nucleotide+polymorphisms+that+are+associated+with+protection+from+hepatic+fibrosis+reduce+TLR4-mediated+inflammatory+and+fibrogenic+signaling+and+lower+the+apoptotic+threshold+of+activated+hepatic+stellate+cells. assertion.
- assertion asSentence TLR4-mediated+activation+of+HIV-LTR+is+largely+governed+by+the+nuclear+factor-kappaB+pathway. assertion.
- assertion asSentence TAG+overexpression+specifically+inhibits+TLR4+signaling. assertion.
- assertion asSentence High+affinity+interactions+between+the+palmitoyl-oleoyl-phosphatidylglycerol+and+the+Toll-like+receptor+4-interacting+proteins+CD14+and+MD-2. assertion.
- assertion asSentence There+is+an+absence+of+association+between+Crohn%27s+disease+and+TLR4+gene+in+the+Tunisian+population. assertion.
- assertion asSentence Cultured+human+melanocytes+express+functional+toll-like+receptors+2-4%2C+7+and+9. assertion.
- assertion asSentence HSP60%2C+TLR4+and+NF-kappaBp65+are+overexpressed+in+the+peripheral+blood+of+patients+with+atopic+dermatitis. assertion.
- assertion asSentence TLR4%2FMyD88+signaling+supports+ovarian+cancer+progression+and+chemoresistance%2C+promoting+immune+escape. assertion.
- assertion asSentence The+TLR4+Asp299Gly+and+Thr399Ile+SNPs+are+not+associated+with+sarcoidosis. assertion.
- assertion asSentence High+expression+of+Toll-like+receptor+4+is+associated+with+colorectal+cancer. assertion.
- assertion asSentence The+functional+TLR4+Asp299Gly+polymorphism+is+associated+with+lower+left+ventricular+mass+in+hypertensive+women. assertion.
- assertion asSentence Single+Nucleotide+Polymorphisms+in+TLR4+gene+is+associated+with+gastric+carcinogenesis. assertion.
- assertion asSentence Altered+linkage+of+hydroxyacyl+chains+in+lipid+A+of+Campylobacter+jejuni+reduces+TLR4+activation+and+antimicrobial+resistance. assertion.
- assertion asSentence Variant+alleles+of+TLR2+and+TLR4+genes+influence+the+susceptibility+to+adverse+effects+of+traffic-related+air+pollution+on+childhood+asthma. assertion.
- assertion asSentence Ni%282%2B%29+triggered+an+inflammatory+response+by+directly+activating+human+Toll-like+receptor+4+%28TLR4%29. assertion.
- assertion asSentence Innate+immune+recognition+of+meningococcal+capsular+polysaccharides+by+macrophages+can+occur+via+TLR2-+and+TLR4-MD-2+pathways. assertion.
- assertion asSentence TLR2+and+TLR4+expression+is+associated+with+poor+outcome+and+higher+inflammatory+response+in+acute+ischemic+stroke. assertion.
- assertion asSentence Increased+expression+of+toll-like+receptor+4+is+associated+with+gastric+dysplasia. assertion.
- assertion asSentence Fumigaclavine+C+attenuated+TNFalpha+via+the+TLR4-NFkappaB+signaling+transduction+pathway. assertion.
- assertion asSentence Toll-like+receptor+4+gene+polymorphisms+do+not+associate+with+normal+tension+glaucoma+in+a+Korean+population. assertion.
- assertion asSentence Toll-like+receptor+4+is+up-regulated+by+mTOR+activation+during+THP-1+macrophage+foam+cells+formation. assertion.
- assertion asSentence Chemerin+enhanced+expression+of+TLR4+and+induced+release+of+CCL2+in+synovial+fibroblasts. assertion.
- assertion asSentence An+interleukin+%28IL%29-27+time-+and+dose-dependent+increase+in+mRNA+and+cell+surface+expression+and+signaling+of+TLR4+is+demonstrated+in+human+monocytes. assertion.
- assertion asSentence Compared+with+controls%2C+expression+of+TLR2+and+TLR4+mRNAs+are+up-regulated+in+patients+with+late+onset+Alzheimer%27s+disease. assertion.
- assertion asSentence FRP+has+the+function+of+evoking+innate+immune+responses+as+one+of+the+endogenous+TLR4+agonists. assertion.
- assertion asSentence Toll-like+receptor+4+expression+decreased+in+the+presence+of+high-molecular-weight+hyaluronan+%28HMW+HA%29+in+cord+blood. assertion.
- assertion asSentence The+Mal-Toll%2Finterleukin-1+receptor+%28TIR%29+domains+AB+loop+is+capable+of+mediating+direct+binding+to+the+TIR+domains+of+TLR4+and+MyD88+simultaneously. assertion.
- assertion asSentence TLR4+mRNA+levels+in+peripheral+monocytes+are+significantly+elevated+in+nondiabetic+hypertensive+patients. assertion.
- assertion asSentence Human+neutrophils+unable+to+induce+the+transcription+of+IFN-beta+in+response+to+TLR4+stimulation+are+able+to+recognize+and+respond+to+microbial+cytosolic+DNA. assertion.
- assertion asSentence A+stop+codon+polymorphism+of+Toll-like+receptor+5+is+associated+with+resistance+to+systemic+lupus+erythematosus. assertion.
- assertion asSentence Toll-like+receptors+4+and+5+induce+distinct+types+of+vasculitis. assertion.
- assertion asSentence TLR5+triggering+induces+activation+of+NF-kappaB%2C+HIV-1+promoter+and+viral+regulatory+sequences+to+reactivate+latent+HIV-1+provirus. assertion.
- assertion asSentence Genetic+variants+of+TLR5+gene+are+associated+with+rheumatic+heart+disease+in+Chinese+Han+population. assertion.
- assertion asSentence Nuclear+orphan+receptor+TLX+induces+Oct-3%2F4+for+the+survival+and+maintenance+of+adult+hippocampal+progenitors+upon+hypoxia. assertion.
- assertion asSentence The+interaction+of+VP26+with+tetraspanin-7+plays+an+essential+role+in+normal+HSV-1+replication. assertion.
- assertion asSentence Loss+of+TSPAN7+is+associated+with+metastasis+in+clear-cell+renal+cell+carcinoma. assertion.
- assertion asSentence Overexpression+of+TMF%2FARA160+downregulates+proangiogenic+genes+and+attenuates+the+progression+of+prostate+cancer+xenografts. assertion.
- assertion asSentence After+abdominal+surgery+there+is+a+concentration+of+up+to+20+mg+thymosin+beta%284%29+per+liter+decreasing+to+about+1+mg%2FL+with+time. assertion.
- assertion asSentence Elevated+expression+of+thymosin+beta4+is+associated+with+early-stage+cervical+cancers. assertion.
- assertion asSentence A+high+in+vivo+and+in+vitro+production+of+TNF-alpha+found+in+carriers+of+the+common+Caucasoid+haplotype+HLA-B8%2CDR3+is+associated+with+multiple+autoimmune+diseases+and+immune+response+dysregulation+in+healthy+subjects. assertion.
- assertion asSentence -A+significantly+reduced+PGN-elicited+tumor+necrosis+factor+alpha+%28TNF-alpha%29+secretion+by+U937+cells+and+rat+alveolar+macrophages. assertion.
- assertion asSentence Transient+exposure+of+human+bronchial+epithelial+cells+to+TNFA+leads+to+persistent+increased+expression+of+ICAM-1. assertion.
- assertion asSentence TNF-alpha+gene+polymorphism+is+related+to+lumbar+spine+bone+area+in+healthy+female+Caucasian+adolescents. assertion.
- assertion asSentence Overexpression+of+mucin+genes+induced+by+tumor+necrosis+factor-alpha+in+cultured+tumor+cells+is+inhibited+by+a+retinoic+acid+receptor+alpha+antagonist. assertion.
- assertion asSentence Native+LDL+potentiate+TNF+alpha+and+IL-8+production+by+human+mononuclear+cells. assertion.
- assertion asSentence Promoter+polymorphism+cosegregates+with+another+polymorphism+and+is+associated+with+the+interleukin-1+beta+%28IL-1+beta%29+synthesis+capacity+of+human+leukocytes. assertion.
- assertion asSentence Impaired+glucose+tolerance+is+not+associated+with+increased+serum+concentrations. assertion.
- assertion asSentence TNF-alpha+plays+a+role+in+the+enhanced+systemic+and+local+production+of+NO+in+congestive+heart+failure+and+is+elevated+in+proportion+to+the+severity+of+CHF. assertion.
- assertion asSentence Crystal+structure+of+a+truncated+epidermal+growth+factor+receptor+extracellular+domain+bound+to+transforming+growth+factor+alpha. assertion.
- assertion asSentence Extracellular+ubiquitin+specifically+inhibits+ex+vivo+secretion+of+tumor+necrosis+factor-alpha+%28TNF-alpha%29+and+TNF-alpha+mRNA+expression+from+peripheral+blood+mononuclear+cells+%28PBMNCs%29+in+response+to+endotoxin+in+a+dose-dependent+manner. assertion.
- assertion asSentence TNF-alpha+can+induce+maturation+of+monocyte-derived+dendritic+cells+and+elicit+sustained+antiviral+cytotoxic+T+lymphocyte+responses%2C+either+alone+or+cooperatively+with+CD40L+or+RANKL. assertion.
- assertion asSentence TNF-alpha+-308+A+allele+is+associated+with+increased+PTFE+graft+thrombosis+and+failure+in+hemodialysis+patients. assertion.
- assertion asSentence TNF-alpha+promotes+macrophage-induced+apoptosis+in+carotid+plaque+vascular+smooth+muscle+cells+by+cooperative+interactions+with+nitric+oxide+and+Fas-Fas+ligand. assertion.
- assertion asSentence In+patients+with+heart+failure%2C+enhanced+platelet+O%282%29%28-%29+production+is+mediated+by+TNF+alpha+via+activation+of+arachidonic+acid+and+NADPH+oxidase+pathways. assertion.
- assertion asSentence No+change+in+level+during+liver+cancer+surgery. assertion.
- assertion asSentence ANG+II%2C+via+AT%281%29R%2C+modulates+the+secretion+of+TNF-alpha+and+MMP-2+from+vascular+endothelial+cells+and+TNF-alpha+mediates+the+effects+of+ANG+II+on+MMP-2+release. assertion.
- assertion asSentence Significantly+higher+in+supernatants+from+Hepatitis+C+virus-infected+primary+human+macrophage+cultures. assertion.
- assertion asSentence In+Polish+TNF-alpha+%28-308A%29+allele+carriers%2C+obesity+correlated+with+insulin+resistance+in+females. assertion.
- assertion asSentence Peptide+fragments+of+gliadin+induced+interleukin+%28IL%29-8+and+tumour+necrosis+factor-alpha+%28TNF-alpha%29+production+in+a+monocytic+cell+line. assertion.
- assertion asSentence Maternal+carriers+of+the+TNF+allele+has+significantly+increased+risk+of+spontaneous+preterm+birth. assertion.
- assertion asSentence The+tnf-alpha+gene+at+position+-308+is+associated+with+preterm+premature+rupture+of+membranes+in+multifetal+pregnancies. assertion.
- assertion asSentence Role+of+TNF-alpha+in+tenascin-W+expression+in+mammary+cancer. assertion.
- assertion asSentence IL-1beta-+and+TNFalpha-mediated+induction+of+IL-6R+shedding+in+osteoblast-like+cells+is+at+least+partly+dependent+on+tumor+necrosis+factor+alpha-converting+enzyme+activation. assertion.
- assertion asSentence Under+physiological+conditions+vitamin+D+activates+only+the+transcription+of+TNF-alpha+gene%2C+for+TNF-alpha+protein+synthesis+additional+cofactors+are+required. assertion.
- assertion asSentence TNF-alpha-308+promoter+polymorphism+is+a+risk+factor+for+acute+kidney+allograft+rejection. assertion.
- assertion asSentence Lactocillus+rhamnosus+reduced+TNFalpha-induced+IL-8+production+by+affecting+the+NFkappaB%2FIkappaB+pathway+in+Caco-2+cells. assertion.
- assertion asSentence TNF-alpha+inhibition+of+endothelial+gene+expression+depends+on+NF-kB. assertion.
- assertion asSentence TNFA+promoter+polymorphisms+are+important+host+genetic+factors+affecting+the+outcomes+of+HBV+infection. assertion.
- assertion asSentence IL-1beta+%2B+TNF-alpha+elicited+innate+immunity+responses+similar+to+those+of+flagellin. assertion.
- assertion asSentence Only+women+carrying+at+least+one+mutant+allele+of+both+polymorphisms+%28tumour+necrosis+factor-alpha+A+and+interleukin-6+C%29+have+a+significantly+elevated+mean+systolic+blood+pressure+and+diastolic+blood+pressure+at+the+end+of+pregnancy. assertion.