Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence In+asthmatic+patients%2C+the+effects+of+the+IL-12B+polymorphism+on+asthma%2C+allergic+rhinitis%2C+familial+asthma%2C+eosinophilia+and+total+IgE+levels%2C+are+controversial. assertion.
- assertion asSentence Genotypic+and+haplotypic+variation+at+IL12Bpro+and+IL12B+3%27+UTR+in+this+population+influences+susceptibility+to+severe+malaria+and+functional+changes+in+circulating+IL-12p40+and+IFN-gamma+levels. assertion.
- assertion asSentence mTOR+pathway+controls+IL-12%2FIL-10+modulation+by+L.+donovani+in+monocyte-dervied+macrophages. assertion.
- assertion asSentence IFN-beta+mediates+suppression+of+IL-12p40+in+human+dendritic+cells+following+infection+with+virulent+Francisella+tularensis. assertion.
- assertion asSentence IL-13+biological+axis+plays+an+important+role+during+the+pathogenesis+of+BOS+independent+of+the+IL-4+biological+axis. assertion.
- assertion asSentence IL-13+promoter+represents+a+dually+active+promoter+element+responsive+to+NF-kappaB+and+NFAT+after+stimulation+by+HTLV-1+oncoprotein+Tax. assertion.
- assertion asSentence Expanded+catalog+of+genetic+loci+implicated+in+psoriasis+susceptibility. assertion.
- assertion asSentence Interleukin-13+mucous+metaplasia+is+also+associated+with+increased+levels+of+rhinoviral+infection. assertion.
- assertion asSentence Polymorphisms+rs7719175+and+rs1800925+in+IL-13+promoter+have+a+synergistic+role+in+the+control+of+infection+levels+caused+by+S.+haematobium. assertion.
- assertion asSentence Epigenetic+regulation+of+the+IL-13-induced+human+eotaxin-3+gene+by+CREB-binding+protein-mediated+histone+3+acetylation. assertion.
- assertion asSentence The+interleukin+13+%28IL-13%29+pathway+in+human+macrophages+is+modulated+by+microRNA-155+via+direct+targeting+of+interleukin+13+receptor+alpha1+%28IL13Ralpha1%29. assertion.
- assertion asSentence Interleukin-15+inhibits+spontaneous+apoptosis+in+human+eosinophils+via+autocrine+production+of+granulocyte+macrophage-colony+stimulating+factor+and+nuclear+factor-kappaB+activation. assertion.
- assertion asSentence IL-15+up-regulates+the+expression+of+lymphocyte+function-associated+antigen-1+%28LFA-1%29+in+IL-7-differentiated+cells+and+augments+their+cytotoxic+activity. assertion.
- assertion asSentence Endogenous+IL-15+plays+a+key+role+in+rendering+resident+naive+CD4+T+cells+susceptible+to+HIV+infection. assertion.
- assertion asSentence There+is+an+auto-inhibitory+mechanism+controlling+cellular+IL-15+levels. assertion.
- assertion asSentence Hepatocytes+and+IL-15+create+a+favorable+microenvironment+for+T+cells+to+growth+and+survive. assertion.
- assertion asSentence IL-7+and+IL-21+are+superior+to+IL-2+and+IL-15+in+promoting+human+T+cell-mediated+rejection+of+systemic+lymphoma+in+immunodeficient+mice. assertion.
- assertion asSentence Recombinant+human+IL-15+administered+to+macaques+generates+a+dramatic+expansion+of+short-lived+memory+CD8+T+cells+and+natural+killer+cells+in+immunocompetent+macaques+and+has+long-term+effects+on+the+balance+of+CD4%28%2B%29+and+CD8%28%2B%29+T+cells. assertion.
- assertion asSentence Respiratory+synctial+virus+increased+IL-15+production+in+respiratory+epithelial+cells+via+virus+replication+and+NF-kB-dependent+mechanisms. assertion.
- assertion asSentence A+quantitative+relationship+is+established+between+receptor+alpha+subunit+binding+affinity+and+mitogenic+activity+for+IL-15+and+IL-2. assertion.
- assertion asSentence IL-2%2C+IL15+and+IL-15Ralpha-IgG1-Fc+complexes+significantly+enhanced+NK+and+CD8%28%2B%29+T+cells+proliferation+and+cytotoxicity. assertion.
- assertion asSentence High+serum+IL-15R+alpha+is+associated+with+T-cell+large+granular+lymphocyte+leukemia. assertion.
- assertion asSentence The+cytokine+IL-16+plays+a+role+in+the+disease+process+underlying+rheumatoid+arthritis+and+joint+destruction. assertion.
- assertion asSentence IL-16+is+a+potent+promoter+of+eosinophil+migration+through+the+extracellular+matrix+components%2C+an+effect+that+is+initiated+via+CD4+and+mediated+via+the+release+of+CCR3+ligand+chemokines. assertion.
- assertion asSentence Increased+levels+of+circulating+IL-16+and+apoptosis+markers+are+related+to+the+activity+of+Whipple%27s+disease. assertion.
- assertion asSentence IL-16+-295+T%3EC+polymorphism+is+significantly+associated+with+a+higher+risk+of+developing+RCC+in+Chinese+population. assertion.
- assertion asSentence Serum+IL-16+levels+of+atopic+dermatitis+patients+correlate+to+some+extent+with+sensitization. assertion.
- assertion asSentence CD137+can+be+enhanced+on+NK+cells+in+an+Fc-dependent+fashion+and+expression+correlates+with+phenotypic+and+functional+parameters+of+activation. assertion.
- assertion asSentence High+macrophage+IL-17+expression+is+associated+with+breast+cancer+invasiveness. assertion.
- assertion asSentence IL-17+production+is+increased+in+systemic+lupus+erythematosus+patients+due+to+the+expansion+of+the+proinflammatory+double+negative+T+cell+subset+and+to+excessive+IL-17+production+of+CD4-positive+T+cells. assertion.
- assertion asSentence IL-17+has+a+role+in+corneal+epithelial+barrier+disruption+in+DE. assertion.
- assertion asSentence Association+of+the+CagA+status+of+Helicobacter+pylori+and+serum+levels+of+interleukin+%28IL%29-17+and+IL-23+in+duodenal+ulcer+patients. assertion.
- assertion asSentence Binding+of+NKG2D+to+UL-16+binding+protein+%28ULB%291+contributes+to+IL-23-dependent+IL-17+production+by+CD4%28%2B%29+cells+in+human+M.+tuberculosis+infection. assertion.
- assertion asSentence During+systemic+inflammation%2C+STAT1-+and+T-bet-deficient+T+cells+each+exhibit+a+hyper-T+helper+type+%28Th%2917+phenotype+relative+to+wild-type+controls. assertion.
- assertion asSentence Important+roles+of+IL-17+and+IL-17-producing+cells+in+the+progression+of+HBV+related+chronic+liver+diseases%2C+especially+in+the+formation+of+liver+fibrosis. assertion.
- assertion asSentence Local+IL-17+production+is+part+of+a+protective+early+immune+response+to+peritoneal+dialysis+related+peritonitis. assertion.
- assertion asSentence IL-1+receptor+type+I-positive+IL-17-secreting+cells+are+highly+enriched+among+central+memory+regulatory+T+cells+%28Treg%29. assertion.
- assertion asSentence cAMP-responsive+element+modulator+%28CREM%29alpha+protein+induces+interleukin+17A+expression+and+mediates+epigenetic+alterations+at+the+interleukin-17A+gene+locus+in+patients+with+systemic+lupus+erythematosus. assertion.
- assertion asSentence IL-18+is+linked+to+raised+IFN-gamma+in+multiple+sclerosis+and+is+induced+by+activated+CD4%28%2B%29+T+cells+via+CD40-CD40+ligand+interactions. assertion.
- assertion asSentence IL-18+production+is+elevated+in+pulmonary+and+pleural+tuberculosis. assertion.
- assertion asSentence IL-18+is+a+primary+proinflammatory+cytokine+in+RA+that+drives+the+local+production+of+IL-1beta+and+TNFalpha. assertion.
- assertion asSentence Interaction+of+PU.1+with+GC-box+binding+protein+is+involved+in+IL-18+transactivation+in+myeloid+cells. assertion.
- assertion asSentence IL-18+105+gene+polymorphism+is+not+correlated+with+endometriosis+development. assertion.
- assertion asSentence Plasma+IL-18+is+increased+in+postinfarction+patients+and+is+associated+with+coronary+atherosclerosis. assertion.
- assertion asSentence Possession+of+the+diplotype+configuration+is+one+of+the+genetic+risk+factors+for+susceptibility+to+juvenile+arthritis+in+the+Japanese+population. assertion.
- assertion asSentence The+presence+of+the+-607+C+allele+correlates+to+HIV-1+infection+and+confers+an+increased+risk+of+infection+in+subjects+carrying+the+single+nucleotide+polymorphism. assertion.
- assertion asSentence Plasma+IL-18+level+is+a+major+independent+inflammatory+predictor+of+90-day+major+adverse+clinical+outcomes+in+acute+ischemic+stroke+patients. assertion.
- assertion asSentence In+primary+Sjogren%27s+syndrome%2C+infiltration+of+the+salivary+gland+by+macrophages+and+dendritic+cells+and+expression+of+IL-18+and+IL-12+play+active+roles+in+infiltrative+injuries+and+have+a+correlation+with+predictors+of+lymphoma+development. assertion.
- assertion asSentence Stimuli+acting+on+different+pathogen-sensing+receptors+converge+on+a+common+pathway+where+ATP+externalization+is+the+first+step+in+the+cascade+of+events+leading+to+inflammasome+activation+and+IL-1beta+and+IL-18+secretion. assertion.
- assertion asSentence Combined+mobilization+and+stimulation+of+tumor-infiltrating+dendritic+cells+and+natural+killer+cells+with+FLT3+ligand+and+IL18+in+vivo+induces+systemic+antitumor+immunity. assertion.
- assertion asSentence Interleukin+18+gene+polymorphism+is+associated+with+the+development+of+acute+lung+injury+after+cardiopulmonary+bypass.+surgery. assertion.
- assertion asSentence IL-18%2FIL-18BP+imbalance+plays+an+important+role+in+pathogenesis+of+primary+immune+thrombocytopenia. assertion.
- assertion asSentence Reduced+IL-18+levels+and+rs360717+and+rs1946519+IL-18+genetic+variants+are+significantly+associated+with+recurrent+spontaneous+miscarriage. assertion.
- assertion asSentence Ectopic+expression+of+human+MutS+homologue+2+on+renal+carcinoma+cells+is+induced+by+oxidative+stress+with+interleukin-18+promotion+via+p38+mitogen-activated+protein+kinase+%28MAPK%29+and+c-Jun+N-terminal+kinase+%28JNK%29+signaling+pathways. assertion.
- assertion asSentence FOXK2+can+promote+transcriptional+activation+and+is+required+for+the+efficient+recruitment+of+AP-1+components+to+chromatin. assertion.
- assertion asSentence CD28+costimulation+activates+AKT+to+phosphorylate+NF90+at+Ser647+and+phosphorylation+triggers+NF90+to+relocate+to+the+cytoplasm+and+stabilize+IL-2+mRNA. assertion.
- assertion asSentence NF90+binds+the+dengue+virus+RNA+3%27+terminus+and+is+a+positive+regulator+of+dengue+virus. assertion.
- assertion asSentence Functions+as+a+downstream+mediator+of+the+ET-1%2FET%28A%29R+axis+to+potentiate+aggressive+cellular+behavior+in+ovarian+cancer+cells. assertion.
- assertion asSentence ILK+activity+can+modulate+acute+Wnt3a+mediated+beta-catenin+phosphorylation%2C+stabilization+and+nuclear+activation+in+a+PI3K-independent+manner. assertion.
- assertion asSentence ILK+regulates+the+expression+of+Her2%2Fneu+through+TWIST+and+YB-1%2C+lending+support+to+the+use+of+ILK+inhibitors+in+the+treatment+of+aggressive+Her2%2Fneu-positive+tumors. assertion.
- assertion asSentence ILK+promoted+proliferation+and+suppressed+apoptosis+via+repressing+phosphorylations+of+the+JNK+signal+pathway+in+human+retinoblastoma+cells. assertion.
- assertion asSentence The+gene+product+of+IMPG1+%28designated+IPM+150%29+is+a+member+of+a+group+of+neuronal+proteoglycans+and%2F+or+glycoproteins+suspected+to+be+essential+in+retinal+adhesion+and+photoreceptor+cell+survival. assertion.
- assertion asSentence Borealin+and+INCENP+associate+with+the+helical+domain+of+Survivin+to+form+a+tight+three-helical+bundle. assertion.
- assertion asSentence Bone+marrow+stromal+cells+express+IDO+protein+and+exhibit+functional+IDO+activity+upon+stimulation+with+IFN-gamma. assertion.
- assertion asSentence IDO+is+a+sensitive+marker+of+atherosclerosis--or+the+inflammatory+response+associated+with+it--but+does+not+have+an+independent+role+in+the+pathogenesis+of+this+disease. assertion.
- assertion asSentence Thymosin+alpha1+can+up-regulate+the+expression+of+ido+mRNA+in+bone+marrow+mesenchymal+stem+cells+from+children+with+aplastic+anemia. assertion.
- assertion asSentence High+IDO+Dioxygenase+is+associated+with+acute+graft-versus-host+disease. assertion.
- assertion asSentence IDO1+activation+represents+a+local+compensatory+mechanism+to+limit+obesity-induced+inflammation+and+hypertension. assertion.
- assertion asSentence p33ING1+triggers+a+senescent+phenotype+in+cultured+primary+fibroblasts+in+a+p53-dependent+fashion. assertion.
- assertion asSentence p33ING2%2FING1L+is+a+DNA+damage-inducible+gene+that+negatively+regulates+cell+proliferation+through+activation+of+p53+by+enhancing+its+acetylation. assertion.
- assertion asSentence ING2+is+upregulated+in+colon+cancer+and+increases+invasion+by+enhanced+MMP13+expression. assertion.
- assertion asSentence Inhibin+A+increases+strongly+in+the+late+follicular+phase. assertion.
- assertion asSentence Inhibin+B+is+a+more+potent+suppressor+of+rat+FSH+release+in+vitro+and+in+vivo+than+inhibin+A. assertion.
- assertion asSentence The+gonadally+derived+Inhibins+are+important+regulators+of+locally+produced+osteotrophic+factors. assertion.
- assertion asSentence Increase+in+Inhibin+A+is+associated+with+breast+cancer. assertion.
- assertion asSentence The+inhibin-alpha+-16C%2FT+and+-124A%2FG+polymorphisms+are+genetic+factors+associated+with+the+prevalence+of+premature+ovarian+failure+in+Korean+women. assertion.
- assertion asSentence Human+amniotic+fluid+activin-A+and+inhibin-A+are+involved+in+biological+processes+linked+to+intra-amniotic+infection%2Finflammation-induced+preterm+birth. assertion.
- assertion asSentence Activin+A+induces+cardiac+ankyrin+repeat+protein+%28CARP%29+in+cultured+intimal+smooth+muscle+cells+in+a+dose-dependent+way. assertion.
- assertion asSentence Mutations+in+INHbetaB+and+INHbetaA+genes+are+not+associated+with+ovarian+failure. assertion.
- assertion asSentence Serum+AMH+and+inhibin+B+are+significantly+lower+in+the+men+with+nonobstructive+azoospermia+compared+to+the+controls. assertion.
- assertion asSentence Cripto+facilitates+Nodal+signaling+and+inhibits+activin+signaling+by+forming+receptor+complexes+with+these+ligands+that+are+structurally+and+functionally+similar. assertion.
- assertion asSentence The+effects+of+activin+on+germ+cells+are+indirect+and+include+mediation+by+the+kit+ligand%2Fc-Kit+pathway%2C+rather+than+being+an+autocrine+germ+cell+effect. assertion.
- assertion asSentence Concentration+of+anti-Mullerian+hormone+and+inhibin-B+in+relation+to+steroids+and+age+in+follicular+fluid+from+small+antral+human+follicles. assertion.
- assertion asSentence Differential+antagonism+of+activin%2C+myostatin+and+growth+and+differentiation+factor+11+by+wild-type+and+mutant+follistatin. assertion.
- assertion asSentence Bone+morphogenetic+protein-6+stimulates+gene+expression+of+inhibin%2Factivin+beta+subunits+in+human+granulosa+cells. assertion.
- assertion asSentence Activin+A+increased+in+asphyxiated+full-term+newborns+with+hypoxic+ischemic+encephalopathy+before+the+appearance+of+related+signs. assertion.
- assertion asSentence High+inhibin+beta+A+is+associated+with+cervical+intraepithelial+neoplasia+grade+3+compared+to+cervical+intraepithelial+neoplasia+grades+1+and+2. assertion.
- assertion asSentence Mutations+in+INHbetaB+and+INHbetaA+genes+are+not+associated+with+ovarian+failure. assertion.
- assertion asSentence The+expression+of+inhibin+betaB+by+Sertoli+cells+is+dependent+on+the+coexistence+of+spermatogenic+activity+within+these+seminiferous+tubules+and+is+low+in+patients+with+Sertoli+cell+only+syndrome. assertion.
- assertion asSentence Discordant+pattern+of+inhibin+A+and+inhibin+B+during+the+rat+estrous+cycle+is+due+to+independent+populations+of+antral+follicles+making+inhibin+B+%28small+antral+follicles%29+or+inhibin+A+%28large+antral+follicles%29. assertion.
- assertion asSentence Hyperplastic+tissue+labelled+more+intensely+than+endometrium+for+the+presence+of+INH-betaA+and+-betaB. assertion.
- assertion asSentence Varicocele+sclerotherapy+improves+inhibin+B+levels+and+seminal+parameters. assertion.
- assertion asSentence Expression+of+the+beta-B+subunit+is+related+to+decidualization+and+can+be+detected+in+the+circulation+as+activin+B. assertion.
- assertion asSentence High+inhibin+beta+B+is+associated+with+cervical+intraepithelial+neoplasia+grades+1+and+2+compared+to+cervix+uteri. assertion.
- assertion asSentence Inhibin-betaB+subunit+appears+not+to+be+a+useful+prognostic+marker+regarding+endometrioid+adenocarcinomas. assertion.
- assertion asSentence The+chemokine+CXCL10%2C+usually+associated+with+Th1+cells%2C+is+elevated+in+serum+of+patients+with+acute+Syndenham%27s+chorea. assertion.
- assertion asSentence Pyelonephritis+in+pregnant+women+is+associated+with+an+increased+maternal+serum+concentration+of+the+chemokine+CXCL10. assertion.
- assertion asSentence CXCL10+in+the+plasma+of+patients+chronically+infected+with+HCV+exists+in+an+antagonist+form%2C+due+to+in+situ+amino-terminal+truncation+of+the+protein. assertion.
- assertion asSentence Chemokine+CXCL10%2C+in+particular%2C+effectively+recruits+isolated+annulus+fibrosis+cells+in+the+process+of+herniated+disc+tissue+repair+and+homeostasis. assertion.
- assertion asSentence Incubation+of+whole+blood+at+39+degrees+C+increased+IP-10+and+IFN-gamma+responsiveness+to+both+Mycobacterium+tuberculosis+antigens+and+mitogen+in+persons+with+baseline+or+initial+low+responses. assertion.