Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence NucNeoR+gained+access+to+this+autophagy-dependent+MHC+class+II+presentation+pathway+by+a+CRM1-independent+route. assertion.
- assertion asSentence Crystal+structure+of+the+Ran-binding+domain+%28RBD%29+from+RanBP3+and+comparison+it+to+RBD+structures+from+RanBP1+and+RanBP2+in+complex+with+Ran+and+CRM1. assertion.
- assertion asSentence Skp1+binding+prevented+Fbxo7+from+contacting+CRM1. assertion.
- assertion asSentence Electrostatic+interactions+involving+the+extreme+C+terminus+of+nuclear+export+factor+CRM1+modulate+its+affinity+for+cargo. assertion.
- assertion asSentence It+mediates+nuclear+export. assertion.
- assertion asSentence CRM1%2C+BARD1+and+Aurora+A+promote+the+targeting+and+function+of+BRCA1+at+centrosomes. assertion.
- assertion asSentence Exportin+1+%28XPO1%29+is+regulated+positively+by+c-Myc+and+negatively+by+p53. assertion.
- assertion asSentence Central+role+for+the+XRCC1+BRCT+I+domain+in+mammalian+DNA+single-strand+break+repair. assertion.
- assertion asSentence Epidermal+growth+factor+and+ionizing+radiation+up-regulate+the+DNA+repair+genes+XRCC1+and+ERCC1+in+DU145+and+LNCaP+prostate+carcinoma+through+MAPK+signaling. assertion.
- assertion asSentence Cumulative+cigarette+smoking+plays+an+important+role+in+altering+the+direction+and+magnitude+of+the+associations+between+the+XRCC1+and+ERCC2+polymorphisms+and+lung+cancer+risk. assertion.
- assertion asSentence XRCC1+polymorphism+and+risks+of+breast+neoplasms+has+no+apparent+association+in+chinese+women. assertion.
- assertion asSentence XRCC1+is+required+for+efficient+DNA+single-strand+break+repair+and+genomic+stability+in+human+cells. assertion.
- assertion asSentence XRCC1+IVS10%2B141G%3EA+is+an+intronic+polymorphism+that+is+associated+with+XRCC1+expression%2C+apoptosis+and+familial+breast+cancer. assertion.
- assertion asSentence Patients+carrying+XRCC1+27466+G%2FG+genotype+develop+chronic+benzene+poisoning. assertion.
- assertion asSentence XRCC1+down-regulation+in+HeLa+cells+leads+to+a+decrease+in+the+DNA+ligase+3+protein+level%2C+significantly+increased+sensitivity+to+alkylating+agents%2C+elevated+level+of+sister+chromatid+exchange+and+decrease+in+the+survival+of+BRCA2-deficient+cells. assertion.
- assertion asSentence No+significant+association+between+the+XRCC1+ARG339Gln+polymorphism+and+the+risk+of+esophageal+adenocarcinoma%2C+Barrett%27s+esophagus+or+reflux+esophagitis. assertion.
- assertion asSentence No+association+is+found+between+the+XRCC1+polymorphism+Arg399Gln+and+gastric+cancer+risk. assertion.
- assertion asSentence Arg399Gln+polymorphism+and+Arg-Gln+haplotype+comprising+XRCC1+Arg194Trp+and+Arg399Gln+polymorphisms+conferred+low+risk+for+gallbladder+cancer+susceptibility. assertion.
- assertion asSentence Single-nucleotide+polymorphism+in+XRCC1+is+associated+with+small-cell+lung+cancer. assertion.
- assertion asSentence Genetic+polymorphisms+in+XRCC1+is+associated+with+radiation+therapy+in+prostate+cancer. assertion.
- assertion asSentence XRCC1+Arg194Trp+polymorphism+is+associated+with+lung+cancer. assertion.
- assertion asSentence Genetic+polymorphisms+of+ERCC1-118%2C+XRCC1-399+and+GSTP1-105+are+associated+with+time+to+progression+and+overall+survival+of+advanced+gastric+cancer+patients+treated+with+oxaliplatin%2F5-Fu-based+combination+chemotherapy. assertion.
- assertion asSentence XRCC1+polymorphisms+Arg194Trp+and+Arg399Gln+is+not+associated+with+colorectal+cancer. assertion.
- assertion asSentence Single-nucleotide+polymorphisms+in+XRCC1+gene+is+associated+with+breast+cancer. assertion.
- assertion asSentence XRCC1-77T%3EC+polymorphism+is+associated+with+neoplasms. assertion.
- assertion asSentence Finds+no+association+between+XRCC2+R188H+polymorphism+and+risk+of+colorectal+adenoma. assertion.
- assertion asSentence Investigation+supports+a+role+for+XRCC2+in+colorectal+cancer+tumorigenesis%2C+conferring+susceptibility+to+rectal+tumors. assertion.
- assertion asSentence Increased+susceptibility+to+genotoxic+agents+with+polymorphisms+in+DNA+repair+genes+XRCC3. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+XRCC3+is+associated+with+breast+cancer. assertion.
- assertion asSentence The+Thr241Met+polymorphism+of+the+XRCC3+gene+can+modify+the+risk+of+colorectal+cancer. assertion.
- assertion asSentence XRCC1+and+XRCC3+gene+polymorphisms+are+useful+as+a+surrogate+marker+of+clinical+outcome+in+colorectal+cancer+with+5-FU%2Foxaliplatin+combination+chemotherapy+in+the+Chinese+population. assertion.
- assertion asSentence A+functional+interaction+of+Ku+with+Werner+exonuclease+facilitates+digestion+of+DNA+containing+8-oxoadenine+and+8-oxoguanine+modifications. assertion.
- assertion asSentence Ku+and+DNA-dependent+protein+kinase+dynamic+conformations+and+assembly+regulate+DNA+binding+and+the+initial+non-homologous+end+joining+complex. assertion.
- assertion asSentence YY1+is+involved+in+a+positive+feedback+loop+during+apoptosis. assertion.
- assertion asSentence Proteasome+inhibitor+NPI-0052+inhibits+the+transcription+repressor+Yin+Yang+1+%28YY1%29+which+regulates+TRAIL+resistance+and+negatively+regulates+DR5+transcription. assertion.
- assertion asSentence Silencing+of+YY1+downregulates+RIZ1+promoter+in+human+osteosarcoma. assertion.
- assertion asSentence C-terminal+region+of+p300+provides+corepressor+function+and+facilitates+the+recruitment+of+p300+and+HDAC3+to+the+YY1-binding+site+and+represses+the+c-Myc+promoter. assertion.
- assertion asSentence Short+hairpin+loop+inhibitory+RNAs+for+human+YY1+and+its+homolog+YY2+caused+significant+changes+in+both+shared+and+distinguishable+gene+sets+in+human+cells. assertion.
- assertion asSentence YY1+is+an+important+activator+of+peripheral+myelination+and+neuregulin+signaling. assertion.
- assertion asSentence Yin+Yang+1+plays+an+essential+role+in+breast+cancer+and+negatively+regulates+p27. assertion.
- assertion asSentence Immunoexpression+of+14-3-3+proteins+in+glial+cytoplasmic+inclusions+of+multiple+system+atrophy. assertion.
- assertion asSentence PKC+delta+in+preeclamptic+placentas+promotes+Bax+dissociation+from+14-3-3+zeta+through+14-3-3+zeta+phosphorylation. assertion.
- assertion asSentence Phosphorylation+by+cAMP-dependent+protein+kinase+strongly+enhanced+interaction+of+tau3+with+14-3-3. assertion.
- assertion asSentence Yeast+BMH1+and+BMH2+possess+a+distinctly+variant+C-terminal+compared+to+human+14-3-3+zeta+protein. assertion.
- assertion asSentence Guggulsterone+targets+14-3-3+zeta+associated+cellular+pathways+for+reducing+proliferation+and+inducing+apoptosis+in+head+and+neck+cancer+cells. assertion.
- assertion asSentence Signaling+through+ZAP-70+is+required+for+CXCL12-mediated+T-cell+transendothelial+migration. assertion.
- assertion asSentence VHR%2C+a+Vaccinia+virus+VH1-related+dual-specific+protein+phosphatase%2C+is+phosphorylated+at+Y138+by+ZAP-70. assertion.
- assertion asSentence Impaired+ZAP-70+activation+is+associated+with+a+unique+signaling+pathway+coupling+TCR+ligation+with+T+cell+proliferation. assertion.
- assertion asSentence Essential+for+T+cell+receptor+signaling+and+CD8+cell+selection. assertion.
- assertion asSentence Zap70+signaling+plays+an+important+role+in+dexamethasone+receptor-mediated+transactivation+of+T+lymphocytes. assertion.
- assertion asSentence A+method+to+index+ZAP-70+protein+expression+levels+to+internal+positive+and+negative+cell+populations+with+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence Cell-permeable+dominant+negative+mutant+form+of+ZAP-70+and+cytoplasmic+domain+of+CTLA-4+synergistically+inhibited+T-cell+activation. assertion.
- assertion asSentence Downregulation+of+ZAP-70+and+P-SYK+during+treatment+with+glucocorticoids+is+not+sufficient+to+induce+apoptosis+in+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence Recruitment+of+PKC-betaII+to+lipid+rafts+mediates+apoptosis-resistance+in+chronic+lymphocytic+leukemia+expressing+ZAP-70. assertion.
- assertion asSentence Pyrosequencing+of+ZAP-70+provides+a+good+alternative+to+flow+cytometry+in+prognosis+of+B+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence High+ZAP-70+expression+is+associated+with+increased+relapse+rate+in+childhood+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence The+KH-QUA2+region+of+SF1+defines+an+enlarged+KH+%28hn+RNP+K%29+fold+which+is+necessary+and+sufficient+for+intron+branched+point+sequence+%28BPS%29+binding. assertion.
- assertion asSentence SF1+and+U2AF+form+extraspliceosomal+complexes+before+and+after+taking+part+in+the+assembly+of+catalytic+spliceosomes. assertion.
- assertion asSentence SF1+silencing+affected+alternative+splicing+of+endogenous+transcripts%2C+establishing+a+previously+unexpected+role+for+SF1+and+branch+site-like+sequences+in+splice+site+selection. assertion.
- assertion asSentence Tristetraprolin+predominantly+regulates+CXCL1%2FKC+chemokine+mRNA+decay+in+mononuclear+phagocytes%2C+acting+via+multiple+3%27-untranslated+region-localized+adenine-uridine-rich+elements. assertion.
- assertion asSentence TTP+can+bind+to+the+2nd+AU-rich+elements+of+cIAP2+mRNA+3%27UTR+and+destabilize+cIAP2+mRNA+by+forming+complexes+with+Dcp2+and+Xrn1. assertion.
- assertion asSentence Tristetraprolin+bound+directly+to+the+IL-17+mRNA+3%27UTR+and+enhanced+decay+of+IL-17+transcripts. assertion.
- assertion asSentence Dandy-Walker+malformation+associated+with+heterozygous+ZIC1+and+ZIC4+deletion. assertion.
- assertion asSentence The+proximal+myotonic+myopathy+phenotype+is+associated+with+DM2-%28CCTG%29%28n%29+expansion+mutations. assertion.
- assertion asSentence CCTG+repeat+expansions+in+the+CNBP+gene+are+responsible+for+myotonic+dystrophy+type+2. assertion.
- assertion asSentence GIOT-4+coactivated+ERbeta+in+ovarian+granulosa+cells. assertion.
- assertion asSentence MKRN3+gene+is+imprinted%2C+with+preferential+expression+from+the+paternal+allele. assertion.
- assertion asSentence Staf+activates+U6+transcription+from+a+preassembled+chromatin+template+in+vitro+and+associates+with+several+proteins+linked+to+chromatin+modification%2C+among+them+chromodomain-helicase-DNA+binding+protein+8+%28CHD8%29. assertion.
- assertion asSentence Efp+controls+breast+cancer+growth+through+ubiquitin-dependent+proteolysis+of+14-3-3sigma. assertion.
- assertion asSentence Viral+nonstructural+protein+1+inhibits+activation+of+RIG-I+by+binding+to+TRIM25. assertion.
- assertion asSentence EFP+mediates+estrogen-induced+ATBF1+protein+degradation+in+breast+cancer+cells. assertion.
- assertion asSentence ZBP-89-mediated+apoptosis+occurs+via+a+p53-independent+mechanism+that+requires+JNK+activation. assertion.
- assertion asSentence ZBP-89+is+an+important+co-activator+of+wild-type+p53+and+both+proteins+are+negatively+affected+by+functionally+inactive+p53+mutants. assertion.
- assertion asSentence ZBP-89+plays+a+role+in+erythroid+and+megakaryocytic+development+by+cooperating+with+GATA-1+and%2For+FOG-1+in+a+developmental+stage-specific+manner. assertion.
- assertion asSentence ZBP-89+is+a+regulator+of+Pdcd4+gene%2C+binding+to+the+basal+promoter+either+alone+or+by+interacting+with+Sp+family+members. assertion.
- assertion asSentence Transcription+factor+Myc-interacting+zinc-finger+protein+1+%28Miz1%29+selectively+suppresses+TNF-alpha-induced+JNK1+activation+and+cell+death+independently. assertion.
- assertion asSentence ZNF217+assembles+a+distinct+set+of+histone+modifying+proteins+at+target+DNA+sites+that+act+synergistically+in+transcriptional+repression. assertion.
- assertion asSentence Exposure+of+sperm+to+ZP+proteins+promoted+acrosomal+exocytosis+and+changed+motility+patterns. assertion.
- assertion asSentence The+functional+activity+of+human+ZP3+resides+in+its+C-terminal+domain. assertion.
- assertion asSentence ZXDA+and+ZXDC+form+an+important+regulatory+complex+for+MHC+II+gene+transcription. assertion.
- assertion asSentence Acting+as+a+negative+regulator+of+RIZ1+function%2C+PRFM2+mediates+effect+of+cell+proliferation+by+estrogen+via+regulation+of+cell+survival+and+differentiating+gene+expression. assertion.
- assertion asSentence In+later+stages+of+cerebral+cortical+development%2C+ApoER2+is+expressed+earlier+than+VLDLR+in+migrating+neurons. assertion.
- assertion asSentence Mutations+interact+with+nephrin+to+produce+either+nephrotic+syndrome+or+focal+glomerosclerosis%2C+depending+on+alleles. assertion.
- assertion asSentence NPHS2+gene+mutations+are+not+a+major+cause+of+chronic+renal+insufficiency+caused+by+sporadic+SRNS+or+heavy+proteinuria+in+Japanese+children. assertion.
- assertion asSentence In+steroid-resistant+nephrotic+syndrome+some+missense+mutations+in+NPHS2+lead+to+misfolding+and+mislocalization+of+mutated+podocin+and+interfere+with+slit+diaphragm+structure+and+function+by+altering+proper+trafficking+of+nephrin+to+plasma+membrane. assertion.
- assertion asSentence Post+kidney+transplantation+recurrence+of+podocin+in+patients+carrying+homozygous+and%2For+heterozygous+posttransplantation+recurrence+of+FSGS+in+patients+originally+carrying+homozygous+and%2For+heterozygous+focal+segmental+glomerulosclerosis+mutations. assertion.
- assertion asSentence Podocin+mutations+are+responsible+for+some+of+both+familial+and+sporadic+steroid-resistant+nephrotic+syndrome+cases+in+Turkey. assertion.
- assertion asSentence Late+steroid-resistant+nephrotic+syndrome+is+not+typically+associated+with+mutations+in+the+NPHS2+gene. assertion.
- assertion asSentence NPHS2+mutations+are+not+a+major+cause+of+familial+steroid-resistant+nephrotic+syndrome+in+Southern+Chinese+Han+ethnic+group. assertion.
- assertion asSentence NPHS1+mutations+associated+with+an+earlier+onset+of+congenital+nephrotic+syndrome+and+worse+renal+outcomes+than+NPHS2+mutations. assertion.
- assertion asSentence T3+upregulates+proliferation+of+LNCaP+cells+by+downregulating+BTG2+gene+expression+through+the+consensus+TRE+pathway. assertion.
- assertion asSentence Sle1+transgene+perturbs+the+action+of+peripheral+tolerance+checkpoints+operative+on+antinuclear+antigen+B+cells+in+both+the+antibody-forming+cell+and+germinal+center+pathways+in+a+cell+autonomous+fashion. assertion.
- assertion asSentence Higher+circulating+leptin+levels+are+associated+with+a+greater+risk+of+congestive+heart+failure+and+cardiovascular+disease. assertion.
- assertion asSentence Levels+of+the+adipocyte-derived+hormones+leptin+and+adiponectin+are+significantly+correlated+with+bronchial+hyperresponsiveness+induced+by+exercise+challenge+in+children+with+asthma. assertion.
- assertion asSentence Compared+with+non-large+artery+atherosclerotic+%28LAA%29+strokes%2C+patients+with+LAA+strokes+have+lower+levels+of+serum+adiponectin+and+a+higher+level+of+leptin-to-adiponectin+ratio. assertion.
- assertion asSentence Mutation+of+ALMS1%2C+a+large+gene+with+a+tandem+repeat+encoding+47+amino+acids%2C+causes+Alstrom+syndrome. assertion.
- assertion asSentence Variation+not+associated+with+NIDDM. assertion.
- assertion asSentence Missense+mutations+within+the+TUBA1A+gene+are+associated+with+specific+abnormalities+in+lissencephaly. assertion.
- assertion asSentence HNF1beta+partially+rescues+Pax8%2Flim1-induced+kidney+malformations. assertion.
- assertion asSentence Pax-8+activity+is+regulated+via+a+redox-based+mechanism+centered+on+the+glutathionylation+of+specific+cysteines+in+the+N-terminal+region+%28Cys45+and+Cys57%29. assertion.