Nanopublications LDF server

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

• NP106040.RAedRO-oMwfBiPQ7zv1fTwbSXOWt6ik_uTDrhpvFO1u2E130_assertion description "[Expression in colorectal carcinomas relating to size and invasiveness of the tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106040.RAedRO-oMwfBiPQ7zv1fTwbSXOWt6ik_uTDrhpvFO1u2E130_provenance.
• NP106041.RAVADvlO7GuDZFDW6voGK1JopGXg5FSKNV5aHi5msVHCA130_assertion description "[protein expression levels of pro- & active MMP-9 were higher in colorectal tumor tissues than in the corresponding normal tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106041.RAVADvlO7GuDZFDW6voGK1JopGXg5FSKNV5aHi5msVHCA130_provenance.
• NP106047.RAZBNu5AwVyYu4vs79qUyJa_RUR_ScbCiOufnWyppgRIY130_assertion description "[MMP-7 activity is upregulated in colorectal cancer liver metastases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106047.RAZBNu5AwVyYu4vs79qUyJa_RUR_ScbCiOufnWyppgRIY130_provenance.
• NP106052.RAdSCXZS7aT1U7E-qFcjkBqUFXHYWxWdSFF8l-GqUnROU130_assertion description "[MMP-7 is an independent prognostic factor for survival in advanced colorectal cancer/our sample, the risk of death associated to MMP-7 increase is much higher than the risk of death associated to lactate dehydrogenase elevation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106052.RAdSCXZS7aT1U7E-qFcjkBqUFXHYWxWdSFF8l-GqUnROU130_provenance.
• NP106057.RAZrgK21p0TwVhQYwP90nHPF7gAXcrMkQHajCgAx1q0O8130_assertion description "[A high proportion of familial microsatellite instability cases and a lower incidence of TP53 mutations were found in Saudi colorectal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106057.RAZrgK21p0TwVhQYwP90nHPF7gAXcrMkQHajCgAx1q0O8130_provenance.
• NP106058.RATySyYTluX4yb2y9ZsS-6PSBBCLvIZLaczsT79YpUgbg130_assertion description "[The data support that the frequencies and patterns of somatic mutation of the p53 genes in colorectal cancer are variable among populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106058.RATySyYTluX4yb2y9ZsS-6PSBBCLvIZLaczsT79YpUgbg130_provenance.
• NP106073.RAQ0ySvSa6ASs-JAnEY_YotBk9z9asIbBxy6EIH9xWXDk130_assertion description "[interaction between ALDH2 and ADH2 polymorphisms may have a role in colorectal cancer in Japan ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106073.RAQ0ySvSa6ASs-JAnEY_YotBk9z9asIbBxy6EIH9xWXDk130_provenance.
• NP106077.RAabLMNuagGMJkaQ2BMpVpZUVthE2Fjus1RuAIBIJNUT8130_assertion description "[This study did not demonstrate an association between NAT2 polymorphisms and inflammatory bowel diseases or sporadic colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106077.RAabLMNuagGMJkaQ2BMpVpZUVthE2Fjus1RuAIBIJNUT8130_provenance.
• NP106090.RAejDx9ocd4_qvEoCXG0ZJIi8iXQdY-MgN3L6FH2g6bNE130_assertion description "[Phospholipase D (2) gene is a susceptibility locus for colorectal cancer in Japanese individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106090.RAejDx9ocd4_qvEoCXG0ZJIi8iXQdY-MgN3L6FH2g6bNE130_provenance.
• NP106093.RAZmaW7j_AkXassD4aO3evMS_g25237oJ98YNNnW8Eym0130_assertion description "[These results suggest that the +869C allele, responsible for a Leu-- > Pro substitution in the signal peptide sequence of the TGF-beta1 protein, may have a predisposing role in the development of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106093.RAZmaW7j_AkXassD4aO3evMS_g25237oJ98YNNnW8Eym0130_provenance.
• NP106097.RASQJw5SiQTFguicJQ1dCNLPF2yaWgANrawReuar9j1OA130_assertion description "[Genetic polymorphisms of methylenetetrahydrofolate reductase is associated with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106097.RASQJw5SiQTFguicJQ1dCNLPF2yaWgANrawReuar9j1OA130_provenance.
• NP106102.RAYwBdqthKIH9HqjhxBxQRw7OA3fh5humgfLh7cugLQzc130_assertion description "[the protective effect of the homozygous variant TT form of the MTHFR genotype (C677T) on the risk of colorectal cancer seems to be modified by the level of methyl diets ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106102.RAYwBdqthKIH9HqjhxBxQRw7OA3fh5humgfLh7cugLQzc130_provenance.
• NP106105.RAWmO91iFy3jwm5ifuRABHpfTDvaWLSaZoe5cW366N4yE130_assertion description "[Study results suggest that MTHFR genotypes are relevant and independent factors of patient outcome in 5FU-based treatment of advanced colorectal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106105.RAWmO91iFy3jwm5ifuRABHpfTDvaWLSaZoe5cW366N4yE130_provenance.
• NP106107.RAd2PoK8S5aQYFzdZj4Ah7B3Xf6Hi6b8Fdi0--ZYeNju8130_assertion description "[The Cys282Tyr mutation is not associated with an increased risk for colorectal cancer in postmenopausal women, although in combination with smoking a slightly increased risk cannot be excluded.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106107.RAd2PoK8S5aQYFzdZj4Ah7B3Xf6Hi6b8Fdi0--ZYeNju8130_provenance.
• NP106111.RAfkYmwIW6Szi_UjgwSXW41oFroXMx-yFhTLGTMUGb2yI130_assertion description "[association beeteen polymorphism and survival in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106111.RAfkYmwIW6Szi_UjgwSXW41oFroXMx-yFhTLGTMUGb2yI130_provenance.
• NP106120.RAcc1M3tyDZiwo_YNIlrn9PuL23WAW6EkUxUB3iXhcsUg130_assertion description "[REVIEW: Role of APC and DNA mismatch repair genes in the development of colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106120.RAcc1M3tyDZiwo_YNIlrn9PuL23WAW6EkUxUB3iXhcsUg130_provenance.
• NP106121.RAWpVr-tCHsQhARMo8oaWlKk4atLuuDGnfGyLRCWrtGSI130_assertion description "[APC E1317Q is not shown to be associated with a clinically meaningful risk of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106121.RAWpVr-tCHsQhARMo8oaWlKk4atLuuDGnfGyLRCWrtGSI130_provenance.
• NP106127.RAbwsRw3LFzukBQg1ki07XM97FO_XOmGLNZRsTxYMamZg130_assertion description "[A nonsense mutation in Arg1114X in the APC gene was found in 5 of 43 colorectal cancer patients/patients also had higher rates of metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106127.RAbwsRw3LFzukBQg1ki07XM97FO_XOmGLNZRsTxYMamZg130_provenance.
• NP106134.RAdg5xqyxZFIH_xn-_Coqup9krgL16ehJO-AZl97GsksE130_assertion description "[data did not support a crucial role of promoter methylation of the E-cadherin gene in the remarkable downregulation of E-cadherin expression in colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106134.RAdg5xqyxZFIH_xn-_Coqup9krgL16ehJO-AZl97GsksE130_provenance.
• NP106136.RAXwqYJbmpPNWfG5-vP8ophEfeucMHnB9HXDijNOHYQ6c130_assertion description "[Data indicate that E-cadherin may modulate Wnt-dependent gene expression in DLD-1 colorectal cancer cells by regulating the availability of beta-catenin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106136.RAXwqYJbmpPNWfG5-vP8ophEfeucMHnB9HXDijNOHYQ6c130_provenance.
• NP106138.RAbP6nYex2RFIkwh7JMpca_GTjom1RycwTnY62geVrSZQ130_assertion description "[overexpression of SRF in colorectal carcinoma cells is associated with modulation of E-cadherin/beta-catenin expression and may play an important role in colorectal cancer metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106138.RAbP6nYex2RFIkwh7JMpca_GTjom1RycwTnY62geVrSZQ130_provenance.
• NP106147.RAcWexJNYO02M1asQJzRJwz8YbZXdeDVl7FOPwwQ8Eyss130_assertion description "[transforming growth factor-beta1 is closely related to the invasion and metastasis of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106147.RAcWexJNYO02M1asQJzRJwz8YbZXdeDVl7FOPwwQ8Eyss130_provenance.
• NP106149.RAVsyO7naR8-wiVUPE9Hgt2jm7bByG5zWZwj6D2SPrcEw130_assertion description "[Overexpression of HER-2 was observed in only a small fraction of colorectal carcinomas, but were frequently accompanied by gene amplification.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106149.RAVsyO7naR8-wiVUPE9Hgt2jm7bByG5zWZwj6D2SPrcEw130_provenance.
• NP106156.RAawf6uBTfA-MRyfxuJla-4dYlGWdMxzFuZU6HumsNIzw130_assertion description "[POLR2F and PRNP exhibited elevated levels in carcinomas compared to normal tissue samples suggesting a possible role for these molecules in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106156.RAawf6uBTfA-MRyfxuJla-4dYlGWdMxzFuZU6HumsNIzw130_provenance.
• NP106163.RAXNWomUDxqUR8aes7KPuQPgFHP2LwqcBPCX2Nh_47yHw130_assertion description "[The expression of pp-GalNAc-T12 seems to be a negative marker especially of metastatic gastric and colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106163.RAXNWomUDxqUR8aes7KPuQPgFHP2LwqcBPCX2Nh_47yHw130_provenance.
• NP106165.RAUIc053iXJVK9fQhSdEi3MYuintWGmCZmPH4Km5PjX9k130_assertion description "[single nucleotide polymorphism of thymidylate synthase in colorectal cancer (Review) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106165.RAUIc053iXJVK9fQhSdEi3MYuintWGmCZmPH4Km5PjX9k130_provenance.
• NP106169.RAdEZPqsfKf4qWiT5Ocqi9ZazlwhM_UPVwEOmuolvxnuI130_assertion description "[thymidylate synthase and dihydropyrimidine dehydrogenase gene polymorphisms have a role in response and toxicity to capecitabine-raltitrexed treatment in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106169.RAdEZPqsfKf4qWiT5Ocqi9ZazlwhM_UPVwEOmuolvxnuI130_provenance.
• NP106172.RAcBMLrMjAJ8XRT2UiMi5HWmmFMQj0eO4ZeE6HXf1GxHw130_assertion description "[The combination of low expression of TS and induction of p16 (INK4a) after chemotherapy can be important indicators of the sensitivity to 5-FU-based chemotherapy in colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106172.RAcBMLrMjAJ8XRT2UiMi5HWmmFMQj0eO4ZeE6HXf1GxHw130_provenance.
• NP106175.RAcB72qoHN_Z5TkUWTwc0-IDfd_sm2CCc29isNIzTNSMw130_assertion description "[Investigators found a relationship between the TSmRNA expression, evaluated by real-time PCR, and with the TS level determined by immunohistochemical assay in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106175.RAcB72qoHN_Z5TkUWTwc0-IDfd_sm2CCc29isNIzTNSMw130_provenance.
• NP106178.RAeq8UZRSVkQAKilo2wyDRmrQ7XR8KaVKQyB7SujbvfnI130_assertion description "[Microsatellite instability and the association with plasma homocysteine and thymidylate synthase was determined in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106178.RAeq8UZRSVkQAKilo2wyDRmrQ7XR8KaVKQyB7SujbvfnI130_provenance.
• NP106179.RARKsYHpDwvat7R2OOFDvHP3p6zufO1f42o5ZCz4JrJ10130_assertion description "[Gene expression is a predictor for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106179.RARKsYHpDwvat7R2OOFDvHP3p6zufO1f42o5ZCz4JrJ10130_provenance.
• NP106182.RAdF7cRrqUZHkYdaswlFMF9ctVGCKc72OByZXwldQ_rnA130_assertion description "[TLR4 expression was up-regulated in non-cancerous tissues or down-regulated in cancerous tissues in patients with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106182.RAdF7cRrqUZHkYdaswlFMF9ctVGCKc72OByZXwldQ_rnA130_provenance.
• NP106188.RAQyUv3aq_Nzodl-frq91o5PXv5s5uD7kUcMCtZSOitYE130_assertion description "[Tumor sections frmo colorectal cancer patients showed elevated expression levels of AKT1, correlating with enhanced cytoplasmic/nuclear expression of beta-catenin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106188.RAQyUv3aq_Nzodl-frq91o5PXv5s5uD7kUcMCtZSOitYE130_provenance.
• NP106193.RAV_-UXs6nOjDSRdvy8oWnu7L6tyg4nUx51KUZiFce6Ac130_assertion description "[Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106193.RAV_-UXs6nOjDSRdvy8oWnu7L6tyg4nUx51KUZiFce6Ac130_provenance.
• NP106198.RAYtz7_cmQoqUJ2b7GEV7eJ3kcQtd2keicOuxMR-KMLbA130_assertion description "[a relationship between the TNFalpha -1031T/T genotype and colorectal cancer (CRC) (64.5% for controls vs 74.7% for CRC cases above 70 yrs) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106198.RAYtz7_cmQoqUJ2b7GEV7eJ3kcQtd2keicOuxMR-KMLbA130_provenance.
• NP106201.RAb3a8esQphl21aGeGPglAZfc0BioMT7rpDxOgPgLsruQ130_assertion description "[Overexpression of the EphA4 gene and reduced expression of the EphB2 gene may thus be a useful predictor of liver metastasis in patients with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106201.RAb3a8esQphl21aGeGPglAZfc0BioMT7rpDxOgPgLsruQ130_provenance.
• NP106206.RAcvNVx_XbDThEKqWS_snyxyHWVfHHRIN4ABvZkbHykD0130_assertion description "[GSTP1 codon 105 polymorphism may be predictive for the response to irinotecan-based chemotherapy in patients with metastatic colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106206.RAcvNVx_XbDThEKqWS_snyxyHWVfHHRIN4ABvZkbHykD0130_provenance.
• NP106207.RAeBOYMT7mIT7E53LhJwRac8VGfDihRwbhhdbyHQ21c7c130_assertion description "[The results of this study suggested that the Ile (105) Val GSTP1 polymorphism may play some role in colorectal cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106207.RAeBOYMT7mIT7E53LhJwRac8VGfDihRwbhhdbyHQ21c7c130_provenance.
• NP106213.RAcA3izE3CSM_j0F-MqUBDxNvmVDEe-2nUI9p99i5UhqI130_assertion description "[study showed that germline allele-specific expression (ASE) of the TGFBR1 gene is a quantitative trait occuring in 10 to 20% of colorectal cancer (CRC) patients & 1 to 3% of controls; estimates suggest ASE confers a substantially increased risk of CRC ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106213.RAcA3izE3CSM_j0F-MqUBDxNvmVDEe-2nUI9p99i5UhqI130_provenance.
• NP106214.RAVhBouNck8Yc3DebeoC_KI0O2Qje8ESOPhiE7TNL7Qx8130_assertion description "[The biotransformation enzymes GSTM1, GSTP1 and EPHX1 may modify the effect of dietary factors on the risk of developing colorectal carcinoma and adenoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106214.RAVhBouNck8Yc3DebeoC_KI0O2Qje8ESOPhiE7TNL7Qx8130_provenance.
• NP106215.RAeisNLtex_1fZlNTryHNuBuqtPGsHJLjP_ziOHk7rADA130_assertion description "[TGFBR2 mutation is associated with CpG island methylator phenotype-high colorectal cancer and indirectly with RUNX3 methylation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106215.RAeisNLtex_1fZlNTryHNuBuqtPGsHJLjP_ziOHk7rADA130_provenance.
• NP106226.RAWany9dQ0k_12ysrbHpc01S6rs6tf7GYtoviTz79T5-w130_assertion description "[Mutation analysis in the coding sequence of thymidine kinase 1 in breast and colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106226.RAWany9dQ0k_12ysrbHpc01S6rs6tf7GYtoviTz79T5-w130_provenance.
• NP106230.RAe44mcj-AWALFHNVH0i_LJqSJ_PJmAtB3Au35K8TaQk8130_assertion description "[the trophic properties of gastrin in colorectal cancer may be mediated in part by transactivation of the EGFR and phosphorylation of ERK1/2, leading to degradation of PPARgamma protein and a decrease in PPARgamma activation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106230.RAe44mcj-AWALFHNVH0i_LJqSJ_PJmAtB3Au35K8TaQk8130_provenance.
• NP106232.RAR2NjydplFvJiWHQaHXKMolxAKOdF6XYsuDpLqGwsL_g130_assertion description "[Frequent polymorphism of peroxisome proliferator activated receptor gamma gene in colorectal cancer containing wild-type K-ras gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106232.RAR2NjydplFvJiWHQaHXKMolxAKOdF6XYsuDpLqGwsL_g130_provenance.
• NP106237.RAdQ2H7VBL2pSq7I7s33b4yH9cJ8osAyjKZHIuE3MSAVM130_assertion description "[Nm23-H1 activity is tissue-specific and is not associated with colorectal cancer progression and prognosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106237.RAdQ2H7VBL2pSq7I7s33b4yH9cJ8osAyjKZHIuE3MSAVM130_provenance.
• NP106245.RAXl_Xx0j3ZVa4-dCJORwE_Vbd1uoyTiB2CxXJYsubtT8130_assertion description "[Elevated expression of cell-cycle regulators p16 (INK4A), p21 (CIP1), and cytoplasmic/nuclear beta-catenin correlated with increased colorectal cancers risk, as did elevated expression of survivin and human telomerase reverse transcriptase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106245.RAXl_Xx0j3ZVa4-dCJORwE_Vbd1uoyTiB2CxXJYsubtT8130_provenance.
• NP106248.RAc7_vjpRx_4Wz6FS-WdV43HjvlqjjpgSS4XDlQuWFKMw130_assertion description "[Tumor sections frmo colorectal cancer patients showed elevated expression levels of AKT1, correlating with enhanced cytoplasmic/nuclear expression of beta-catenin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106248.RAc7_vjpRx_4Wz6FS-WdV43HjvlqjjpgSS4XDlQuWFKMw130_provenance.
• NP106255.RAV_kl1DknZw1KnCXb7SflzOFjrb3kj3zPj4mG92uA2Ag130_assertion description "[beta-catenin nuclear accumulation plays a role in Dukes'D human colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106255.RAV_kl1DknZw1KnCXb7SflzOFjrb3kj3zPj4mG92uA2Ag130_provenance.
• NP106256.RAf9RcU1gFWNL70bXzGhZyWju76W6P8vIicdlSw-N0OwY130_assertion description "[beta-catenin may have a role in progression of colorectal neoplasms to metastatic liver lesions ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106256.RAf9RcU1gFWNL70bXzGhZyWju76W6P8vIicdlSw-N0OwY130_provenance.
• NP106257.RAfCd5nx5MKhh5MmWTOmlYkeDPoUdG5sh0HO6TRONkTwI130_assertion description "[accumulation of beta-catenin in colorectal cancer is related to chromosomal instability ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106257.RAfCd5nx5MKhh5MmWTOmlYkeDPoUdG5sh0HO6TRONkTwI130_provenance.
• NP106258.RAckWO_6Fgaq0xYwuundMl4eYx0YsRz44X_v5QVIRIXAM130_assertion description "[A functional crosstalk between hepatocyte growth factor receptor (MET) and beta-catenin signaling sustains and increases colorectal carcinoma cell invasive properties.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106258.RAckWO_6Fgaq0xYwuundMl4eYx0YsRz44X_v5QVIRIXAM130_provenance.
• NP106259.RAexFupa7VIjvAbeiaJMDUupDm7qvzuDJE_wYk5mz3ob0130_assertion description "[beta-catenin has a role in progression of colorectal neoplasms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106259.RAexFupa7VIjvAbeiaJMDUupDm7qvzuDJE_wYk5mz3ob0130_provenance.
• NP106260.RAa2Bcj86VCQyEx4df6nNsie8z4LflCRs52yC0f2ajDDw130_assertion description "[the cross talk of KLF4 and beta-catenin plays a critical role in homeostasis of the normal intestine as well as in tumorigenesis of colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106260.RAa2Bcj86VCQyEx4df6nNsie8z4LflCRs52yC0f2ajDDw130_provenance.
• NP106265.RAXaO31ZWdhjncXp8KbC1vHxUcNK3QZVNuk5LJgd2IU6Q130_assertion description "[four MUTYH SNPs, IVS1+11C > T, IVS6+35G > A, IVS10-2A > G, and 972G > C (Gln324His), for an association with increased CRC risk in a population-based series of 685 colorectal cancer patients and 778 control subjects from Kyushu, Japan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106265.RAXaO31ZWdhjncXp8KbC1vHxUcNK3QZVNuk5LJgd2IU6Q130_provenance.
• NP106266.RAXj_t0_dJ_l9ibGRJzhCWXqF3dkYKN_6QKWbJsqUy1Ag130_assertion description "[Colorectal cancer has an important genetic component/polyposis associated with mutations in the MYH gene is an autosomal recessive syndrome characterized by the development of colorectal adenomas and cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106266.RAXj_t0_dJ_l9ibGRJzhCWXqF3dkYKN_6QKWbJsqUy1Ag130_provenance.
• NP106269.RAZeGcH0uJEAzodFsmZW9ICB6j4bc51uAxQKtFIouxTc4130_assertion description "[the prevalence of pathogenic MUTYH mutations was increased among familial colorectal cancer patients compared to sporadic colorectal cancer and controls ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106269.RAZeGcH0uJEAzodFsmZW9ICB6j4bc51uAxQKtFIouxTc4130_provenance.
• NP106270.RAdp3CnKE4tzA93H65judvTaZYITHsydKHnPiWi2iEoiU130_assertion description "[The role of MYH gene in genetic predisposition to colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106270.RAdp3CnKE4tzA93H65judvTaZYITHsydKHnPiWi2iEoiU130_provenance.
• NP106273.RAcaxsHyT2B1x0gAhrlIzODUyVClHUKiXYK7IUy_4ufME130_assertion description "[Mutations in the MUTYH gene have been reported to be associated with increased risk of developing colorectal cancer/study underscores the need for large sample sizes in order to identify small gene effects when the disease allele frequency is low.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106273.RAcaxsHyT2B1x0gAhrlIzODUyVClHUKiXYK7IUy_4ufME130_provenance.
• NP106274.RAYxMzGjID9tLAgz-kPlPKy8iPhwU8oE9CDAwgITp8uOo130_assertion description "[Mutation spectrum for MYH by direct DNA sequencing in 219 anonymous North Americans in genetic testing for polyposis colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106274.RAYxMzGjID9tLAgz-kPlPKy8iPhwU8oE9CDAwgITp8uOo130_provenance.
• NP106277.RASIaKtQV0VZIIuAwMv3JV8PN3qUAg6Nif58Qy2lRvHmU130_assertion description "[Transversions in KRAS2 or APC are more common in colorectal cancers with single germ-line MYH variants than colorectal cancers with wild-type MYH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106277.RASIaKtQV0VZIIuAwMv3JV8PN3qUAg6Nif58Qy2lRvHmU130_provenance.
• NP106279.RAbTGXNWluXfJ5-gKQr1sTe3Qg-XkyQCDTgYHSdmwkDU4130_assertion description "[Andrographolide inhibits human colorectal cancer Lovo cell growth by G1-S phase arrest and inducing the expression of p53, p21 and p16.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106279.RAbTGXNWluXfJ5-gKQr1sTe3Qg-XkyQCDTgYHSdmwkDU4130_provenance.
• NP106280.RAXYYdTEojYVfgI98vW4YbjgGLTG_QwyTcZouAQJFIGoo130_assertion description "[Patients with primary colorectal cancer with low TSP-1 expression, with or without detection of mp53 gene product, are more likely to harbor lymph node metastasis than patients with higher expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106280.RAXYYdTEojYVfgI98vW4YbjgGLTG_QwyTcZouAQJFIGoo130_provenance.
• NP106285.RASW_GTt7Tx0MnCZweT7qmy5UEn-c1o2opHjrj5RWjDHw130_assertion description "[We aimed to investigate the expression pattern of p53, Bcl-2 and C-Myc in colorectal cancer (CRC) tissues obtained from Egyptian colorectal cancer patients divided in two different groups, associated with and without Schistosoma mansoni.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106285.RASW_GTt7Tx0MnCZweT7qmy5UEn-c1o2opHjrj5RWjDHw130_provenance.
• NP106292.RAcpqxKBYMEImjGB65DaCWBefd2a0tyHUyeSprVsNkKh0130_assertion description "[Elevated expression of cell-cycle regulators p16 (INK4A), p21 (CIP1), and cytoplasmic/nuclear beta-catenin correlated with increased colorectal cancers risk, as did elevated expression of survivin and human telomerase reverse transcriptase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106292.RAcpqxKBYMEImjGB65DaCWBefd2a0tyHUyeSprVsNkKh0130_provenance.
• NP106298.RAYrn_zoATwjTTUHX7RsLVLi5mVxJEIdXKphkDHFOGUQ4130_assertion description "[FXYD3 interacts with Na (+) -K (+) -Exchanging ATPase in colorectal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106298.RAYrn_zoATwjTTUHX7RsLVLi5mVxJEIdXKphkDHFOGUQ4130_provenance.
• NP106301.RATKQdo2fnfU6AJ3V9MTQ9iXXeu71_8pj-nGClkVkUk-A130_assertion description "[Data show that the P286S, R702W, G908R, and 1007fs mutations of Nod2 were more frequent among colorectal cancer patients than controls and that the presence of the 1007fs variant might also be associated with young patient age.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106301.RATKQdo2fnfU6AJ3V9MTQ9iXXeu71_8pj-nGClkVkUk-A130_provenance.
• NP106302.RAXbdcuGOHOW17HG_TSnnXtimdJM9pCZ0eEsPiKpN4jtU130_assertion description "[CARD15 influences susceptibility to colorectal cancer, but we have found no evidence to indicate that CARD15 mutations predict the clinicopathologic characteristics of this disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106302.RAXbdcuGOHOW17HG_TSnnXtimdJM9pCZ0eEsPiKpN4jtU130_provenance.
• NP106307.RAR0cNGoZxXcsj8-3o3LzcqOAirEbowfpVl1gAGYD2niY130_assertion description "[DOC1 has a differential expression in microsatellite-unstable human colorectal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106307.RAR0cNGoZxXcsj8-3o3LzcqOAirEbowfpVl1gAGYD2niY130_provenance.
• NP106310.RAbZITjxOwkd5orvh-6czXcR_KWpiKrQqaN0Yexcy2fzU130_assertion description "[PvuII and XbaI polymorphisms in the ER-alpha gene were associated with the risk of developing microsatellite instability in colorectal cancer patients/BsmI polymorphism in the VDR gene was linked to the risk of developing colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106310.RAbZITjxOwkd5orvh-6czXcR_KWpiKrQqaN0Yexcy2fzU130_provenance.
• NP106312.RAU9GocEjdAzF9lEvVHgQIFEyBbumW5SH6J2iW0L6ZK5E130_assertion description "[Topoisomerase IIalpha overexpression is significantly associated with alterations in tumor behavior and response to drug treatment in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106312.RAU9GocEjdAzF9lEvVHgQIFEyBbumW5SH6J2iW0L6ZK5E130_provenance.
• NP106313.RAe9isTvCQeXbU3gPZbwNIeftrkizVliziVfVyOEdzg_s130_assertion description "[a reduced expression of the claudin-7 gene might lead to venous invasion and liver metastasis in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106313.RAe9isTvCQeXbU3gPZbwNIeftrkizVliziVfVyOEdzg_s130_provenance.
• NP106314.RAbD0uvNMZvUfqKckXm1S0hWdkiaN-R37NfXjY7MRPh98130_assertion description "[MUC2 was isolated from an adenomatous colorectal neoplasm tumor line and the effect of chitinase on it was studied.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106314.RAbD0uvNMZvUfqKckXm1S0hWdkiaN-R37NfXjY7MRPh98130_provenance.
• NP106319.RAXMAb4neFz-fSK2AH3m_36EF5QkU--1ewYLkRdrRQfW8130_assertion description "[Report genetic alterations of K-ras in Korean colorectal cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106319.RAXMAb4neFz-fSK2AH3m_36EF5QkU--1ewYLkRdrRQfW8130_provenance.
• NP106321.RAYf4ww_IN11U_2Qp7waK9IDm9uphjCFtA_pkyvotDZLM130_assertion description "[The data support that the frequencies and patterns of somatic mutation of the K-ras gene in colorectal cancer are variable among populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106321.RAYf4ww_IN11U_2Qp7waK9IDm9uphjCFtA_pkyvotDZLM130_provenance.
• NP106322.RAdDzdhDcXzTZK0LjlxZJvHYpYnhpUzOm9HoUl63hD4lA130_assertion description "[CpG island methylator phenotype in colorectal neoplasms may result from activating mutations in either BRAF or KRAS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106322.RAdDzdhDcXzTZK0LjlxZJvHYpYnhpUzOm9HoUl63hD4lA130_provenance.
• NP106324.RAa-pwAv_3KIYZLcnjluL7epUO3NZHYc67fVpJ_8QFOTs130_assertion description "[KRAS mutations are associated with cetuximab failure in EGFR FISH+ colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106324.RAa-pwAv_3KIYZLcnjluL7epUO3NZHYc67fVpJ_8QFOTs130_provenance.
• NP106326.RAcKkTBJnCZUvPL5WBtqwkI2_QPZQEhYYXjPyEfdFHGvc130_assertion description "[CpG island methylator phenotype (CIMP+) in ColoRectal Cancer (CRC) is associated with low expression of GGH, suggesting involvement of the folate pathway in the development of this phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106326.RAcKkTBJnCZUvPL5WBtqwkI2_QPZQEhYYXjPyEfdFHGvc130_provenance.
• NP106327.RATIx1ycnTPr7z_MCYTa6nRE0-aZoh6m-Fkiv3WyM3rvA130_assertion description "[Specific T-cell immunity against Ki-ras peptides in patients with pancreatic and colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106327.RATIx1ycnTPr7z_MCYTa6nRE0-aZoh6m-Fkiv3WyM3rvA130_provenance.
• NP106331.RAV_TfFBd-OwbBQSmBca4Hc7FzI_aHhXfBy6ibyN9Jmag130_assertion description "[data support the notion that K-ras-dependent inhibition of anoikis plays an important casual role in colorectal carcinoma progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106331.RAV_TfFBd-OwbBQSmBca4Hc7FzI_aHhXfBy6ibyN9Jmag130_provenance.
• NP106332.RAe9Se8dbF2BooePDg3SGzkvpCCLIg8VYQb0FrsNpH1HE130_assertion description "[RAS signaling network is extensively dysregulated in colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106332.RAe9Se8dbF2BooePDg3SGzkvpCCLIg8VYQb0FrsNpH1HE130_provenance.
• NP106334.RAR2QQCuO-dZVo0Cl-psPiaTwm4_1XbSE_C_FWk-QzEww130_assertion description "[a significant association of L1 expression and presence of disseminated tumor cells colorectal tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106334.RAR2QQCuO-dZVo0Cl-psPiaTwm4_1XbSE_C_FWk-QzEww130_provenance.
• NP106339.RAW1Zfk2H6Kj-BdI4DvXHl295RCeWS_q-5vunFfJK5SqU130_assertion description "[The expression of claudin-1, -3 and -4 was upregulated 5.7-, 1.5- and 2.4-fold, respectively, in colorectal tumor tissues in comparison to the normal ones.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106339.RAW1Zfk2H6Kj-BdI4DvXHl295RCeWS_q-5vunFfJK5SqU130_provenance.
• NP106342.RAd_-vYWzmE4v4nUt8Qz0jKkmaaWMyCAfCK_6pDABoXQU130_assertion description "[Fhit protein has a role in development of colorectal neoplasm ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106342.RAd_-vYWzmE4v4nUt8Qz0jKkmaaWMyCAfCK_6pDABoXQU130_provenance.
• NP106351.RAdMX5554rF5A19ozn0vahC_JqV7yGIsBc-r1ffNhU1s4130_assertion description "[The immunohistochemical expression of p34 (cdc2) is independently associated with lymph node metastasis in colorectal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106351.RAdMX5554rF5A19ozn0vahC_JqV7yGIsBc-r1ffNhU1s4130_provenance.
• NP106357.RAfXLqg3kmFPUUZ_pEVRqv90iCGHMe3NBSXp4D6tC3Y5o130_assertion description "[Cycloheximide sensitizes colorectal tumor cells to TNF-alpha induced apoptosis by reducing FLIP levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106357.RAfXLqg3kmFPUUZ_pEVRqv90iCGHMe3NBSXp4D6tC3Y5o130_provenance.
• NP106364.RAYM4LRVwf0eP7cVKq1wZfv4rtAEKxwkCCM7ocHXiKhts130_assertion description "[FES has a growth suppressive function in colorectal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106364.RAYM4LRVwf0eP7cVKq1wZfv4rtAEKxwkCCM7ocHXiKhts130_provenance.
• NP106369.RAebQVIvbKsDUXpnJHHXyILcGCprfS_DAe7bYcQXG27GQ130_assertion description "[PUMA expression may be of minor importance in the development of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106369.RAebQVIvbKsDUXpnJHHXyILcGCprfS_DAe7bYcQXG27GQ130_provenance.
• NP106371.RAf8Wi0AqrM1hr5Pf5phhG_fcGyEbIoQ0W6wFhkiYVAdc130_assertion description "[Elevated phospholipase D2 is associated with colorectal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106371.RAf8Wi0AqrM1hr5Pf5phhG_fcGyEbIoQ0W6wFhkiYVAdc130_provenance.
• NP106373.RAZORMjYDcL-R4EoxBVoVe0uitHtrKhMv1fZxPqyX0Ins130_assertion description "[Nm23-H1 may play an important role in suppressing the early steps of metastasis in sporadic cases of colorectal carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106373.RAZORMjYDcL-R4EoxBVoVe0uitHtrKhMv1fZxPqyX0Ins130_provenance.
• NP106380.RAbMIVJcpYwmh7_S4fnA4eBLf9Ei-JRWtLs0pzYWWh9nw130_assertion description "[Although genomic rearrangements of MSH6 play a small role in the spectrum of all mutations predisposing to hereditary non-polyposis colorectal cancer (HNPCC), up to 10-20% of patients with MSH6 negative tumors harbor germline rearrangements in this gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106380.RAbMIVJcpYwmh7_S4fnA4eBLf9Ei-JRWtLs0pzYWWh9nw130_provenance.
• NP106391.RAeVSQ2yldNgK8Q250FAIORVWeFesbV7qTksVw9IINfP0130_assertion description "[Overexpression of HIF-1alpha is associated with angiogenesis and tumor progression via regulation of VEGF in human colorectal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106391.RAeVSQ2yldNgK8Q250FAIORVWeFesbV7qTksVw9IINfP0130_provenance.
• NP106392.RASbEaUcGhlBBULgpp9aE-HdBUsPcfJKUPTcEsc82Lp9Y130_assertion description "[comparison of the expression of HIF-1alpha and GLUT-1 with various clinicopathological features of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106392.RASbEaUcGhlBBULgpp9aE-HdBUsPcfJKUPTcEsc82Lp9Y130_provenance.
• NP106395.RASTqCQxcYyDKqae9c-r4NsyAl05r_7IQ_0T6x8muIQzk130_assertion description "[Mutations highly frequent in microsatellite unstable (MSI-H) colon cancers and cause loss of ACVR2, indicating biallelic gene nactivation/of activin signaling through mutation of ACVR2 may have role in genesis of MSI-H colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106395.RASTqCQxcYyDKqae9c-r4NsyAl05r_7IQ_0T6x8muIQzk130_provenance.
• NP106396.RAb6jgmYuDaJpy4yUFs7rFW_T3k-3R2YJJmUdwdpJzPZI130_assertion description "[results suggest that 5-lipoxygenases is up-regulated in colorectal cancer and that inhibition of its expression might be valuable in the prevention and treatment of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106396.RAb6jgmYuDaJpy4yUFs7rFW_T3k-3R2YJJmUdwdpJzPZI130_provenance.
• NP106397.RAYhDNXe5Ijq2JyWpX0Ox2sjEfH0iZ1H5BRdK_VQNCXWc130_assertion description "[The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106397.RAYhDNXe5Ijq2JyWpX0Ox2sjEfH0iZ1H5BRdK_VQNCXWc130_provenance.
• NP106407.RARHDNWWALYNDBJ-jvTaiYhlK331-NFInL2fchSUVuBJU130_assertion description "[Cysteine148Arginine variant is associated with a moderately increased risk of colorectal cancer, both in sporadic and familial cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106407.RARHDNWWALYNDBJ-jvTaiYhlK331-NFInL2fchSUVuBJU130_provenance.
• NP106409.RAa7BpqD_pxa-gE1j7T5SEJPLqn9M9jKAjgqO66VRmalM130_assertion description "[A T434+2C mutation was found in familial colorectal cancer DNA suggesting a limited role for this gene in the devlopment of CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106409.RAa7BpqD_pxa-gE1j7T5SEJPLqn9M9jKAjgqO66VRmalM130_provenance.
• NP106411.RAW-IpaCBGWNQzDUMZWtVjxbX0cem5xTGZsVxjgwPVcbg130_assertion description "[MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106411.RAW-IpaCBGWNQzDUMZWtVjxbX0cem5xTGZsVxjgwPVcbg130_provenance.
• NP106413.RAb2dQnV8qNXyTwEcy4sHggoEhOwHgkVdzx7muTKTKeAM130_assertion description "[Little evidence for involvement of MLH3 in colorectal cancer predisposition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106413.RAb2dQnV8qNXyTwEcy4sHggoEhOwHgkVdzx7muTKTKeAM130_provenance.
• NP106433.RAS9IdG_MS9IExhyr2iMScQEXSJ-u5azappZnVDMfgF7s130_assertion description "[mutations and functional polymorphisms in multidrug resistance 1 gene: correlation with microsatellite instability and lymphoid infiltration in colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106433.RAS9IdG_MS9IExhyr2iMScQEXSJ-u5azappZnVDMfgF7s130_provenance.

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