Nanopublications LDF server

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

• NP106438.RAc1nViW4Zh0vweZSRL2KZcVyB9pTR_WGPoDgaFrQOoTs130_assertion description "[Intensive follow-up by serial assay of CEA and cytokeratins allows early detection of colorectal neoplasm recurrence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106438.RAc1nViW4Zh0vweZSRL2KZcVyB9pTR_WGPoDgaFrQOoTs130_provenance.
• NP106439.RASjVa0isIswL3ElnBrNqXbKLjC0SC66lHS3jJpHF3hH8130_assertion description "[Loss of expression of CDX2 protein may play an important role in the tumorigenesis of colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106439.RASjVa0isIswL3ElnBrNqXbKLjC0SC66lHS3jJpHF3hH8130_provenance.
• NP106440.RATutFjQkOEeStGVWRCO9LfKq8A_IG2Je1JqZLkUuULgQ130_assertion description "[findings suggest caudal type homeo box transcription factor 2 (CDX2) inactivation in colon cancer results from defects in trans-acting pathways regulating CDX2 transcription, and CDX2 silencing contributes to altered phenotype of some colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106440.RATutFjQkOEeStGVWRCO9LfKq8A_IG2Je1JqZLkUuULgQ130_provenance.
• NP106441.RAblvLFwVx6w0xV4vl_HISC_EXICG6ayNo5z0r0zIprMY130_assertion description "[the major factors determining the presence of CDX-2 in colorectal carcinomas at the protein product level may include cancer location and the solid phenotype of the tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106441.RAblvLFwVx6w0xV4vl_HISC_EXICG6ayNo5z0r0zIprMY130_provenance.
• NP106445.RASJknevM0a5GZnjABQNmd5dZIlJmquVtaAKW_JHyhs1k130_assertion description "[Andrographolide inhibits human colorectal cancer Lovo cell growth by G1-S phase arrest and inducing the expression of p53, p21 and p16.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106445.RASJknevM0a5GZnjABQNmd5dZIlJmquVtaAKW_JHyhs1k130_provenance.
• NP106450.RAc4Th_iRvl2xW95DP_B7zk7OIY7DlWOYbgK9DGkzY8LU130_assertion description "[A microRNA encoded in an intron of the gene EVL, is commonly suppressed in human colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106450.RAc4Th_iRvl2xW95DP_B7zk7OIY7DlWOYbgK9DGkzY8LU130_provenance.
• NP106451.RAcSi7P7SX7Bpqi4aHggmi-e2jolYw__GZo0V2Zmfo3pw130_assertion description "[mRNA expression analyses revealed PRR5 overexpression in a majority of colorectal tumors but substantial downregulation of PRR5 expression in a subset of breast tumors and reduced expression in two breast cancer cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106451.RAcSi7P7SX7Bpqi4aHggmi-e2jolYw__GZo0V2Zmfo3pw130_provenance.
• NP106456.RAfF_9HEhj6mVr1oycZYAJ6fQ30bP3nZOJs5exCWGwERI130_assertion description "[Methylation testing of fecal DNA using a panel of epigenetic markers (methylated SFRP2, HPP1 and MGMT) may be a simple and promising non-invasive screening method for colorectal carcinoma and precancerous lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106456.RAfF_9HEhj6mVr1oycZYAJ6fQ30bP3nZOJs5exCWGwERI130_provenance.
• NP106461.RAfa8v7OP9ITq825UXjLlq-xn27HhkeFChxEvRAX1Z6lQ130_assertion description "[Results strongly suggest an association between IL-8 expression, induction and progression of colorectal carcinoma and the development of colorectal liver metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106461.RAfa8v7OP9ITq825UXjLlq-xn27HhkeFChxEvRAX1Z6lQ130_provenance.
• NP106467.RAYRNJS8yaGkzgeMe1Sx7WAMWkKsH12BRNu02cAF7zt1Q130_assertion description "[RAD50/MRE11/NBS1 proteins interacted with each other, which had different clinicopathological significance in microsatellite-stable and -unstable colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106467.RAYRNJS8yaGkzgeMe1Sx7WAMWkKsH12BRNu02cAF7zt1Q130_provenance.
• NP106471.RAeCPStYjbyvMRLeRipJz7JxX8lR_UHN6MZZULF71N4Rc130_assertion description "[the cross talk of KLF4 and beta-catenin plays a critical role in homeostasis of the normal intestine as well as in tumorigenesis of colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106471.RAeCPStYjbyvMRLeRipJz7JxX8lR_UHN6MZZULF71N4Rc130_provenance.
• NP106481.RAaCNLQu-iIM1-3UiAwEtNpL8d5xevGA9BODa9HiQTfLM130_assertion description "[Our results suggest that the presence of -1575G allele in the MMP-2 promoter region may be of significance in the assessment of colorectal cancer risk and invasive potential.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106481.RAaCNLQu-iIM1-3UiAwEtNpL8d5xevGA9BODa9HiQTfLM130_provenance.
• NP106483.RAWSuKazMoMGx_3uVeJPYYcPDGfrAPtDNTUAyPeW1VIfo130_assertion description "[colorectal carcinoma patients with the 2G/2G genotype for the MMP-1 single nucleotide polymorphisms had significantly better 5-year survival compared to patients with a 1G allele (P < 0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106483.RAWSuKazMoMGx_3uVeJPYYcPDGfrAPtDNTUAyPeW1VIfo130_provenance.
• NP106487.RARiUeX8YnitPQAs0LcJcD31i7ESxmK8q0HKLvjTnHolU130_assertion description "[The up-regulation of SLC6A14 may have a pathogenic role in colorectal neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106487.RARiUeX8YnitPQAs0LcJcD31i7ESxmK8q0HKLvjTnHolU130_provenance.
• NP106494.RAQO66V8Z4fRKZ8L6AzCwGtuv190REunnt1yTmfIoYloQ130_assertion description "[hereditary breast and colorectal cancer syndrome, if it exists as a separate entity, is not likely to be due to CHEK2 mutations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106494.RAQO66V8Z4fRKZ8L6AzCwGtuv190REunnt1yTmfIoYloQ130_provenance.
• NP106499.RAXbwIcFsXJBNEO1-41RHPuJbgPVJYt_ePcJeygGAY1QU130_assertion description "[Defective tapasin transcription and thus absence of HLA-B44 expression is associateed with colorectal tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106499.RAXbwIcFsXJBNEO1-41RHPuJbgPVJYt_ePcJeygGAY1QU130_provenance.
• NP106503.RATKNfZAeFfeGnn4Xaeg2Nv3KScfD1q8M-veAztik3UCQ130_assertion description "[The results show that ZNF278 promotes cell growth, and its knockdown suppresses cell proliferation/could be a potential proto-oncogene in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106503.RATKNfZAeFfeGnn4Xaeg2Nv3KScfD1q8M-veAztik3UCQ130_provenance.
• NP106504.RAYyFN6PA3dLKwGY0teVZ2fUvHpwnYVbtzVI-g4R4GmlA130_assertion description "[Finds IGFBP3 2133C variant allele associated with lower circulating IGFBP-3 hormone levels and an increased risk of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106504.RAYyFN6PA3dLKwGY0teVZ2fUvHpwnYVbtzVI-g4R4GmlA130_provenance.
• NP106505.RATMzBwiDNuKuDfhX9VLsEm9cdfH3b8r8LByzjBVqK5DE130_assertion description "[microsatellite instability in CPG-island-metahylator-high colorectal cancers, & this relationship is limited to p53-negative tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106505.RATMzBwiDNuKuDfhX9VLsEm9cdfH3b8r8LByzjBVqK5DE130_provenance.
• NP106515.RAX0FnfXg5D8kg6ufFh5lCarGiy688TWcFVx-ct-5uOF8130_assertion description "[Folate intake and tumors harboring BRAF mutations and between vitamin B6 intake and those showing MLH1 hypermethylation were associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106515.RAX0FnfXg5D8kg6ufFh5lCarGiy688TWcFVx-ct-5uOF8130_provenance.
• NP106518.RASBsz8FJu_1uoXhBWIInpUBaP_rMY5BbQjy_Mcv470xY130_assertion description "[Left-sided microsatellite unstable colorectal cancers show significantly less frequent methylation of hMLH1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106518.RASBsz8FJu_1uoXhBWIInpUBaP_rMY5BbQjy_Mcv470xY130_provenance.
• NP106519.RAZaKqdpl558cyIvNaJ_9Y6M8riqCktSpBAsVsGACoIQs130_assertion description "[Previous studies may have wrongly estimated association between methylation of the MLH1 gene and the lack of its protein expression in colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106519.RAZaKqdpl558cyIvNaJ_9Y6M8riqCktSpBAsVsGACoIQs130_provenance.
• NP106521.RAeoQqqNaYNOrVUTY8TPU6oW0clfX_w3Pa0DQHiv0jVPQ130_assertion description "[It is concluded that the rare foci of hypermethylation of the MLH1 promoter in normal colon epithelium from people with colorectal cancer is associated with silencing of the gene that may play a role in the early evolution of these neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106521.RAeoQqqNaYNOrVUTY8TPU6oW0clfX_w3Pa0DQHiv0jVPQ130_provenance.
• NP106525.RAc2H8WIqqas2Uad_s2L1yNTCXsndTEdIY3n0dCCoVkUk130_assertion description "[MSH3 abrogation may be a predictor of metastatic disease or even favor tumor cell spread in MLH1-deficient colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106525.RAc2H8WIqqas2Uad_s2L1yNTCXsndTEdIY3n0dCCoVkUk130_provenance.
• NP106528.RAdQQOCcs4aKvlyE0Ah6InkotD7sDLb3Vza1Nb0XmpR_E130_assertion description "[microsatellite instability Colorectal cancer patients with low Bcl-2 and hMLH1 and hMSH2 demonstrate a significantly shorter disease-free survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106528.RAdQQOCcs4aKvlyE0Ah6InkotD7sDLb3Vza1Nb0XmpR_E130_provenance.
• NP106530.RAU05BRGq1B5jOL4LUcvfzfN0kTAa2_aerIsbc5yAQkQ0130_assertion description "[Extensive promoter methylation was associated with MLH1 inactivation, microsatellite instability, and BRAF mutation in sporadic colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106530.RAU05BRGq1B5jOL4LUcvfzfN0kTAa2_aerIsbc5yAQkQ0130_provenance.
• NP106537.RAWwl70NAnkPqmDaq3tIgYG_Col4Ya0VxOt_f2rny8hH0130_assertion description "[in hereditary non-polyposis colorectal cancer families, a proclivity to multiple tumours in the same subject & higher tumour burden per family were most relevant findings in affected patients with founder mutation compared to other MLH1 or MSH2 mutations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106537.RAWwl70NAnkPqmDaq3tIgYG_Col4Ya0VxOt_f2rny8hH0130_provenance.
• NP106540.RAQ72AhA0OFE1gEgaEgIvK5viswuSgigcAAFFsbvPKHnQ130_assertion description "[expression status of mismatched repair genes hMLH1, the incidence of microsatellite instability high colorectal cancer in populations based study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106540.RAQ72AhA0OFE1gEgaEgIvK5viswuSgigcAAFFsbvPKHnQ130_provenance.
• NP106548.RAb5_kk7oY17H2pIf3JX-Plo0G1zutSSauCW7q6hVqqKQ130_assertion description "[This study investigates microsatellite instability in multiple primary colorectal cancers, and the relevance of MLH1, MSH2, and MSH6 gene expression in hereditary nonpolyposis colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106548.RAb5_kk7oY17H2pIf3JX-Plo0G1zutSSauCW7q6hVqqKQ130_provenance.
• NP106551.RAURxjJ1ace1qhg6raW4bKmHwEOPlYD9EZ_lpnCOxcos4130_assertion description "[Insulin-like growth factor-I CA repeat is an important modifier of disease onset in hereditary non-polyposis colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106551.RAURxjJ1ace1qhg6raW4bKmHwEOPlYD9EZ_lpnCOxcos4130_provenance.
• NP106560.RAVPhEIS88utJMwESD0UqzZHErIfSXlXXP-roBF3bggPU130_assertion description "[DPD may have a role in progression of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106560.RAVPhEIS88utJMwESD0UqzZHErIfSXlXXP-roBF3bggPU130_provenance.
• NP106567.RAV-_Um1VeCTJ5U-4Ksr1Sn1B-EZj_Xf4aU1iSHZzR-1s130_assertion description "[These results indicate that MGMT and/or p16 aberrant methylation may play an important role in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106567.RAV-_Um1VeCTJ5U-4Ksr1Sn1B-EZj_Xf4aU1iSHZzR-1s130_provenance.
• NP106574.RAV68OAyrv6DIgmN3FHkwHgQPcMMiKi1XlW1HQlki6fRU130_assertion description "[Pak-1 has a role in human colorectal tumor invasiveness and motility ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106574.RAV68OAyrv6DIgmN3FHkwHgQPcMMiKi1XlW1HQlki6fRU130_provenance.
• NP106575.RAXOp23heIgggvW9BhiEU5PHk2lKDuoRemMQgjx0w08BU130_assertion description "[hepatocyte growth factor signaling and Ki-ras oncogene activation have roles in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106575.RAXOp23heIgggvW9BhiEU5PHk2lKDuoRemMQgjx0w08BU130_provenance.
• NP106577.RAVIR2deg4AL6KwXhbjXRUJjfNS5K6XCgG0MDeU59j9AI130_assertion description "[A functional crosstalk between hepatocyte growth factor receptor (MET) and beta-catenin signaling sustains and increases colorectal carcinoma cell invasive properties.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106577.RAVIR2deg4AL6KwXhbjXRUJjfNS5K6XCgG0MDeU59j9AI130_provenance.
• NP106578.RAQIA8JkBZQkQxxZIFiuxr048gRX8O-mWRKEw0pAkThyo130_assertion description "[Examined associations between BRAF mutations, morphology, and apoptosis in early colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106578.RAQIA8JkBZQkQxxZIFiuxr048gRX8O-mWRKEw0pAkThyo130_provenance.
• NP106583.RATz3wSnlD7vTaAEvrFxlV5oMPsnXteVOva9jAvB7RoSw130_assertion description "[BRAF mutations in colorectal cancer microsatellite-stable cases are associated with high levels of chromosomal instability that are likely responsible for the adverse outcomes in these cases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106583.RATz3wSnlD7vTaAEvrFxlV5oMPsnXteVOva9jAvB7RoSw130_provenance.
• NP106590.RAYRTbO6sdB08rawkKAK8glLbUAIobZDZwPX7SJ8ZG_Sk130_assertion description "[A role for BRCA1/2 mutations in colorectal cancer risk in a subgroup of breast cancer and/or ovarian cancer affected carriers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106590.RAYRTbO6sdB08rawkKAK8glLbUAIobZDZwPX7SJ8ZG_Sk130_provenance.
• NP106592.RAYqA7WYKPcMOIo-Ko41P_ESHELb6MH-i2vNsLOotIWkQ130_assertion description "[combined analysis of N stage, vascular invasion, and RKIP expression is highly predictive of distant metastasis in patients with mismatch repair--proficient colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106592.RAYqA7WYKPcMOIo-Ko41P_ESHELb6MH-i2vNsLOotIWkQ130_provenance.
• NP106597.RAYxcEvExHDK6UCJgTlfQ0prLF_kASC0FfUdDEGY04BAs130_assertion description "[PRL-3 expression in colorectal cancers may contribute to the establishment of liver metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106597.RAYxcEvExHDK6UCJgTlfQ0prLF_kASC0FfUdDEGY04BAs130_provenance.
• NP106601.RAbwxZnSgCKbnIo2JX1Utdi-OryhjVmX_TMF2JEQVbNjA130_assertion description "[genetic polymorphisms of UGT1A as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106601.RAbwxZnSgCKbnIo2JX1Utdi-OryhjVmX_TMF2JEQVbNjA130_provenance.
• NP106604.RAZPZ0O8HbipIGsnphI-l5CU3sqHEjbY2mIV46Mbx_2F4130_assertion description "[identified as one of five genes containing 11 somatic mutations in a panel that included 132 colorectal cancers, then demonstrated that down-regulation of such homologs resulted in chromosomal instability and chromatid cohesion defects in human cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106604.RAZPZ0O8HbipIGsnphI-l5CU3sqHEjbY2mIV46Mbx_2F4130_provenance.
• NP106612.RAS3f0iH4blLZPL4CKpD3ByHbD1TsUd8g1l1QzY4Z5QkY130_assertion description "[Theses findings illustrate the biologic significance of JAK1, 2/STAT3 signaling in colorectal cancer (CRC) progression and provide novel evidence that the JAK/STAT3 pathway may be a new potential target for therapy of CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106612.RAS3f0iH4blLZPL4CKpD3ByHbD1TsUd8g1l1QzY4Z5QkY130_provenance.
• NP106614.RARq_es67_Kh90yn62KUPO0WYVWYyG-x9Z18e_xNP7_oU130_assertion description "[SNC19/ST14 gene overexpression could enhance invasion of colorectal cancer cells in vitro significantly and influence early cell adherence to ECM, but could not change cell movement significantly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106614.RARq_es67_Kh90yn62KUPO0WYVWYyG-x9Z18e_xNP7_oU130_provenance.
• NP106617.RAcnONTI1X4Ig_2nROc7Pj5luXdc3ipT_R_3I4885ZMzs130_assertion description "[Colorectal neoplasms showed a loss of expression of MCT2 in plasma membranes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106617.RAcnONTI1X4Ig_2nROc7Pj5luXdc3ipT_R_3I4885ZMzs130_provenance.
• NP106618.RASJ_5PS7cGxN5u2F5rhY-4dYVzRmo0yd6xGo2ESkdOmQ130_assertion description "[The adult RARbeta2 isoform also shows age-related methylation in normal tissues but more variable methylation in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106618.RASJ_5PS7cGxN5u2F5rhY-4dYVzRmo0yd6xGo2ESkdOmQ130_provenance.
• NP106628.RAXU2CJcGSlQ675L_LYNqIqxWXC-Xgc6JCo_bRhEi80YQ130_assertion description "[Interaction of beta-catenin with FUS/TLS and other RNA-binding proteins involved in the regulation of pre-mRNA splicing in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106628.RAXU2CJcGSlQ675L_LYNqIqxWXC-Xgc6JCo_bRhEi80YQ130_provenance.
• NP106633.RAU-Gxxf28StQGvZcSf00BiqoqvBsAI39g9y0jhCw_638130_assertion description "[Significant coexpression of GLUT-1, Bcl-xL, and Bax points to cooperation of all three regulatory proteins in elimination due to irreversible injury, adaptation to hypoxia, reduction of further damage, and survival of colorectal cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106633.RAU-Gxxf28StQGvZcSf00BiqoqvBsAI39g9y0jhCw_638130_provenance.
• NP106640.RAWFRExDqJh6KEXOEklYaJ5EVN1fM9VKf_4dUrl5OCEY0130_assertion description "[possible deregulation of the mechanisms that control bcl-2 expression in high-grade and advanced-stage colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106640.RAWFRExDqJh6KEXOEklYaJ5EVN1fM9VKf_4dUrl5OCEY0130_provenance.
• NP106651.RAXab_DkIZHYo47-bILZDzXYkpNThcUmjY6mIVHlqY6j4130_assertion description "[identified as one of five genes containing 11 somatic mutations in a panel that included 132 colorectal cancers, then demonstrated that down-regulation of such homologs resulted in chromosomal instability and chromatid cohesion defects in human cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106651.RAXab_DkIZHYo47-bILZDzXYkpNThcUmjY6mIVHlqY6j4130_provenance.
• NP106654.RAcRaeKHgw_lp-ZWn6o7ghwm0-P8xArLkZZDZLYceZj3k130_assertion description "[By inhibiting NF-kappaB, suppression of BAG-1 could represent a novel strategy to impede colorectal cancer cell survival and as an adjuvant increase sensitivity to current therapeutic regimes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106654.RAcRaeKHgw_lp-ZWn6o7ghwm0-P8xArLkZZDZLYceZj3k130_provenance.
• NP106655.RAUXmM2rMiMvB-zDwt8kZeR__wxS4fKj7ibqY4yfNOAeI130_assertion description "[promoter hypermethylation of MAL was present in the vast majority of benign and malignant colorectal tumors, and only rarely in normal mucosa ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106655.RAUXmM2rMiMvB-zDwt8kZeR__wxS4fKj7ibqY4yfNOAeI130_provenance.
• NP106659.RARdpgtKYjIDu583ZhkGxpxc63s-nJo87JVManExTjfnM130_assertion description "[UGT1A7 polymorphisms may have a significant modifying effect on colorectal cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106659.RARdpgtKYjIDu583ZhkGxpxc63s-nJo87JVManExTjfnM130_provenance.
• NP106660.RAaiYrRkEttUS2RWoJ4JPBpahudVm2pA5lYncOWiluoSQ130_assertion description "[carriage of the UGT1A7*3 allele, as well as variant-211 UGT1A1 allele represents a risk factor for the development of, and a determinant for, metastases associated with colorectal cancer patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106660.RAaiYrRkEttUS2RWoJ4JPBpahudVm2pA5lYncOWiluoSQ130_provenance.
• NP106661.RAaN-v0hJ5W3V65mvWd3lFXj8jAQ3rUdOZcaBzIHhsPUk130_assertion description "[Genetic polymorphisms in UGT1A7 is associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106661.RAaN-v0hJ5W3V65mvWd3lFXj8jAQ3rUdOZcaBzIHhsPUk130_provenance.
• NP106665.RAdzfBY7FXqKoapH3FSLMDs9FS44hRnR0MZ1Wg_uuDaho130_assertion description "[results show that dysregulation of the matriptase/HAI-1 mRNA ratio occurs early during colorectal cancer carcinogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106665.RAdzfBY7FXqKoapH3FSLMDs9FS44hRnR0MZ1Wg_uuDaho130_provenance.
• NP106674.RAbQhFSj_CQWiFCl7XVe1_8AGjUw3FdAl1eM2YaXyxpBg130_assertion description "[K-ras mutations were observed in 68/182 (37.4%) cases of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106674.RAbQhFSj_CQWiFCl7XVe1_8AGjUw3FdAl1eM2YaXyxpBg130_provenance.
• NP106676.RATRc3H9DJy_iyvCbjNF3LC98j1kW5BLxfSe0yV5YNxq0130_assertion description "[K-ras mutations are found in plasma after colorectal tumor resection ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106676.RATRc3H9DJy_iyvCbjNF3LC98j1kW5BLxfSe0yV5YNxq0130_provenance.
• NP106678.RASTu3dS0Xncgi3x5F2B64Ux8JriOKh6VA-HQ-aovf8DQ130_assertion description "[VEGF-C expression may induce lymphangiogenesis in colorectal cancer, as a result, tumor cells can entry the lymphatic vessels easily.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106678.RASTu3dS0Xncgi3x5F2B64Ux8JriOKh6VA-HQ-aovf8DQ130_provenance.
• NP106683.RAWAX2zYeIHvBNWlg9joBsWQ_dfK8n-WNMJp1jwiGamT0130_assertion description "[Colorectal cancer patients had increased plasma VEGF-A, but not endoglin levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106683.RAWAX2zYeIHvBNWlg9joBsWQ_dfK8n-WNMJp1jwiGamT0130_provenance.
• NP106684.RAVi-0s3WGkojfHrp_qy306hDUvuyndy_8Iz9ZB8WTjzw130_assertion description "[Activator protein-4 expression was associated with the expression of matrix metalloproteinase-9 and vascular endothelial growth factor in the advanced colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106684.RAVi-0s3WGkojfHrp_qy306hDUvuyndy_8Iz9ZB8WTjzw130_provenance.
• NP106686.RASgvqn65lEvvIyEChedpp5bnhyr04OCKluDaZpQjDQVw130_assertion description "[data suggest that in primary colorectal cancer, presurgery circulating VEGF levels are related to VEGF produced by tumour-associated macrophages ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106686.RASgvqn65lEvvIyEChedpp5bnhyr04OCKluDaZpQjDQVw130_provenance.
• NP106687.RARSCKGz2SvZrIaUH8YSytREiTAXNbSOd7mkVGgG44CHQ130_assertion description "[Expression of VEGF and Ref-1 is associated with Trx-1 overexpression, and poor prognosis in patients with liver metastases from colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106687.RARSCKGz2SvZrIaUH8YSytREiTAXNbSOd7mkVGgG44CHQ130_provenance.
• NP106688.RAUxueCby4tthdFJEF0dINGCTSXLdKEes-lTBfRcGA75U130_assertion description "[IL-8 is responsible for tumor progression and liver metastasis of colorectal cancer (CRC), and activation of plasminogen activator system induced by IL-8 and VEGF may play important role in progression of CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106688.RAUxueCby4tthdFJEF0dINGCTSXLdKEes-lTBfRcGA75U130_provenance.
• NP106691.RAVZwLGxpsjGhwU40WUBE4mqkk0nQvabO42O2DfR8bmXY130_assertion description "[data suggest that mutations of p53 and activation of the Ras/MAPK pathway may play a role in the induction of VEGF expression in human colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106691.RAVZwLGxpsjGhwU40WUBE4mqkk0nQvabO42O2DfR8bmXY130_provenance.
• NP106699.RAfElrSMgZ8DOGzcTV601nY7Cf9UesqtAT4B4ZxheLvo8130_assertion description "[LRP is expressed in colorectal cancer and forms complexes with u-PA and its inhibitor ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106699.RAfElrSMgZ8DOGzcTV601nY7Cf9UesqtAT4B4ZxheLvo8130_provenance.
• NP106709.RAduczAyhWpljiGt2vrfPg3dhXAhcm1FrZQipk-mc-0B8130_assertion description "[Among colorectal cancer patients, ODC activity in cancer tissue was correlated with T factors, lymph node metastasis and stages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106709.RAduczAyhWpljiGt2vrfPg3dhXAhcm1FrZQipk-mc-0B8130_provenance.
• NP106712.RAUv2-eIKl6-LecGWcFByPobpdB2tHz1OcuzGmZJbLQaE130_assertion description "[inactivation of AIM2 by genetic and epigenetic mechanisms is frequent in Mismatch repair -deficient colorectal cancers, thus suggesting that AIM2 is a mutational target relevant for the progression of MSI-H colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106712.RAUv2-eIKl6-LecGWcFByPobpdB2tHz1OcuzGmZJbLQaE130_provenance.
• NP106714.RAQCq7uimYXvaJt1cY261IQL_q4-JzLNthVogbmo3QXXY130_assertion description "[IDO significantly contributes to disease progression and overall survival in patients with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106714.RAQCq7uimYXvaJt1cY261IQL_q4-JzLNthVogbmo3QXXY130_provenance.
• NP106715.RASTB8ggSbISd_4V1Mh2qMxtLXSfzshyPWjXpbIXYg6WY130_assertion description "[Increased p53, CEA, and CA 19-9 serum levels are associated with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106715.RASTB8ggSbISd_4V1Mh2qMxtLXSfzshyPWjXpbIXYg6WY130_provenance.
• NP106716.RARkeqOA7npebudYJHRLkvcqPQt3cHT_4mhMRPbOuOwSQ130_assertion description "[Polymorphisms in the mismatch repair gene, MSH3 is associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106716.RARkeqOA7npebudYJHRLkvcqPQt3cHT_4mhMRPbOuOwSQ130_provenance.
• NP106719.RASXMOHMA83-mlFG_7FXolJ97mpvlBPb7RSI6UBaMVL20130_assertion description "[Overexpression of this protein plays an important role for aneuploidy in colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106719.RASXMOHMA83-mlFG_7FXolJ97mpvlBPb7RSI6UBaMVL20130_provenance.
• NP106724.RAUJK7-wN3CQCR8m3LjqHMl6zZx4jSMpeKA_m6JBq9uwo130_assertion description "[CDX1 is downregulated after promoter methylation in colorectal tumor cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106724.RAUJK7-wN3CQCR8m3LjqHMl6zZx4jSMpeKA_m6JBq9uwo130_provenance.
• NP106732.RAWwxy5-HGNFk3WV6wylZVRH65wm49xcJbthDTP-3g5N8130_assertion description "[CDH13 promoter methylation is associated with poorly differentiated colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106732.RAWwxy5-HGNFk3WV6wylZVRH65wm49xcJbthDTP-3g5N8130_provenance.
• NP106733.RARrdekkOFoKWQ74c-sRhgStRIPLrS7YaU1hSkYGwS514130_assertion description "[EGF A61G genotype has a functional influence on EGF gene expression in normal colon in colorectal cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106733.RARrdekkOFoKWQ74c-sRhgStRIPLrS7YaU1hSkYGwS514130_provenance.
• NP106734.RAe-CBmUMQ4dG3PUjuiazdo6sOG_XYPbvLekP-ez8VcMY130_assertion description "[Increased interleukin-6 is associated with staging of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106734.RAe-CBmUMQ4dG3PUjuiazdo6sOG_XYPbvLekP-ez8VcMY130_provenance.
• NP106736.RAeCQZ4DYum6_LBVhpdRPX1oU-un_CgUmVJoinHIvowBI130_assertion description "[IL-4 gene expression-related polymorphism is associated with the development of initial stages of colorectal cancer, while in advanced stages IL-4 levels appear to be less important ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106736.RAeCQZ4DYum6_LBVhpdRPX1oU-un_CgUmVJoinHIvowBI130_provenance.
• NP106749.RAX_YCoOGnCuXTC6GL0VPoeGTGs4sUg-m8VmYolfeHWRY130_assertion description "[AKAP10 2073A > G variation is associated with an increased risk of colorectal cancer in the Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106749.RAX_YCoOGnCuXTC6GL0VPoeGTGs4sUg-m8VmYolfeHWRY130_provenance.
• NP106755.RAfUq9rrMOpReZ_VkeBzRcnGbXWCVM5XK4cK7y1OKxN9U130_assertion description "[A G44T missense mutation was found in familial colorectal cancer DNA suggesting a limited role for this gene in the devlopment of CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106755.RAfUq9rrMOpReZ_VkeBzRcnGbXWCVM5XK4cK7y1OKxN9U130_provenance.
• NP106756.RASAf1jSv0JaSQVjbmMypotzpxB_jfJ4tF-O4R0qTPXu0130_assertion description "[The recombinant proteins of IGFBP1 (IGFBP-rP1) induce senescence-like growth arrest in colorectal cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106756.RASAf1jSv0JaSQVjbmMypotzpxB_jfJ4tF-O4R0qTPXu0130_provenance.
• NP106757.RAZDFoIx_Kr8U5t_I5YgfA9-qoU5Malgpb1N_9V0Lpb54130_assertion description "[Overexpression of IGF2 was found to play an important role in carcinogenesis of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106757.RAZDFoIx_Kr8U5t_I5YgfA9-qoU5Malgpb1N_9V0Lpb54130_provenance.
• NP106759.RAX4QJyzrmbQh2ll8cEhZZYWtgyp9DqcwcGClFhCgVVFc130_assertion description "[investigated the utility of loss of IGF2 imprinting as a marker of colorectal cancer risk ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106759.RAX4QJyzrmbQh2ll8cEhZZYWtgyp9DqcwcGClFhCgVVFc130_provenance.
• NP106768.RAWniaR9CjBQim7LpPP1ZCllZQQhhLB1nvlRx6r2oyfJM130_assertion description "[Comethylation of promoters of p16 and MGMT genes could have a prognostic value in patients with colorectal cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106768.RAWniaR9CjBQim7LpPP1ZCllZQQhhLB1nvlRx6r2oyfJM130_provenance.
• NP106771.RAamfMCysk78wzfLS7qmkkaINJc7hmqVhwBKXpYM8SPS0130_assertion description "[PAI-1 overexpression in esophageal and colorectal cancers might originate from higher PAI-1 expression in corresponding normal tissues and result in a malignant phenotype of these cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106771.RAamfMCysk78wzfLS7qmkkaINJc7hmqVhwBKXpYM8SPS0130_provenance.
• NP106772.RAfoCtgWa7K4sYjOglMkOteoNduAbIlsHXueiwNBzSoI8130_assertion description "[overexpression of c-Met is associated with advanced stage colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106772.RAfoCtgWa7K4sYjOglMkOteoNduAbIlsHXueiwNBzSoI8130_provenance.
• NP106773.RAaFM54dXLsh4YXUGpc8dUYAW017Oj825fcg6zU70fb2I130_assertion description "[Src family kinases activity is important for the growth of colorectal cancer cell lines, although only low activity levels are required ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106773.RAaFM54dXLsh4YXUGpc8dUYAW017Oj825fcg6zU70fb2I130_provenance.
• NP106774.RAWT1rEKdDGX-c9lotN6NwBO8SZty5OrY6SIYh3cuHNNk130_assertion description "[Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106774.RAWT1rEKdDGX-c9lotN6NwBO8SZty5OrY6SIYh3cuHNNk130_provenance.
• NP106776.RAXwEmyMEcS3KYx726QJ6WOEuzrcTdSrrF5dC9chm8dJg130_assertion description "[KLF9 may be involved in the carcinogenesis of human colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106776.RAXwEmyMEcS3KYx726QJ6WOEuzrcTdSrrF5dC9chm8dJg130_provenance.
• NP106778.RAUg59-O0sgTA17hoJUPwOOFilIK88KgyDh1_ZhUak-Mg130_assertion description "[Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106778.RAUg59-O0sgTA17hoJUPwOOFilIK88KgyDh1_ZhUak-Mg130_provenance.
• NP106779.RAcPmt5tfNV2s8MewHudhJDYnUwZc0Ymb9NheVpHVQ6-A130_assertion description "[RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1a.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106779.RAcPmt5tfNV2s8MewHudhJDYnUwZc0Ymb9NheVpHVQ6-A130_provenance.
• NP106780.RAR6GZBDilBTujDWqqLI88ZkXHy3i-xpWHL62--5KJ7vA130_assertion description "[RASSF1A is hypermethylated in early flat-type colorectal tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106780.RAR6GZBDilBTujDWqqLI88ZkXHy3i-xpWHL62--5KJ7vA130_provenance.
• NP106788.RAYyBAIF60IM0Pttq7H7w_IRsuvkRnW4Y9D09ttkkEaoQ130_assertion description "[The expression of ST13 decreases in colorectal cancer tissue compared with that in adjacent normal tissue/is mostly expressed in colorectal epithelia and adenocarcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106788.RAYyBAIF60IM0Pttq7H7w_IRsuvkRnW4Y9D09ttkkEaoQ130_provenance.
• NP106791.RAYPoggglgeOQmN5aTJhU3ogpiIjV27hLd02IpAhWJ-yY130_assertion description "[Our data indicate that MDM2-SNP309 is a modifier of the age at colorectal cancer onset for patients whose tumors have a wild-type p53 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106791.RAYPoggglgeOQmN5aTJhU3ogpiIjV27hLd02IpAhWJ-yY130_provenance.
• NP106795.RAeS0mzrkaIUCQjaOVtY9qc6Gk1Al3OWPN2oY8re5ai98130_assertion description "[MCC is a nuclear, beta-catenin-interacting protein that can act as a potential tumor suppressor in the serrated colorectal cancer pathway by inhibiting Wnt/beta-catenin signal transduction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106795.RAeS0mzrkaIUCQjaOVtY9qc6Gk1Al3OWPN2oY8re5ai98130_provenance.
• NP106796.RAUrtdbQESb0Vkk2YY7o7BYPIqDjgCVnskt663Ts0KyKI130_assertion description "[The XRCC1 RNA expression was correlated with microsatellite instability status in colorectal cancer tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106796.RAUrtdbQESb0Vkk2YY7o7BYPIqDjgCVnskt663Ts0KyKI130_provenance.
• NP106797.RAaBXFd1DkfWJ-UCXoDZBZqoVtVFuj2HsiloGaGZVAtgI130_assertion description "[the trophic properties of gastrin in colorectal cancer may be mediated in part by transactivation of the EGFR and phosphorylation of ERK1/2, leading to degradation of PPARgamma protein and a decrease in PPARgamma activation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106797.RAaBXFd1DkfWJ-UCXoDZBZqoVtVFuj2HsiloGaGZVAtgI130_provenance.
• NP106799.RAUOPeSZIkTxmz74MleFSTN9uU63FaXwt8rza896O0F6k130_assertion description "[proteomic analysis of possible role of heat shock protein 10 in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106799.RAUOPeSZIkTxmz74MleFSTN9uU63FaXwt8rza896O0F6k130_provenance.
• NP106801.RAdWbsBtLLtPCy9kGmueNKoPi_Zz1kExIxPFi6Rd15gdc130_assertion description "[FZD7-siRNA may be used as a therapeutic reagent for colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106801.RAdWbsBtLLtPCy9kGmueNKoPi_Zz1kExIxPFi6Rd15gdc130_provenance.
• NP106804.RAT7TqdUUDLpqZY0daBQmYbO-uKzenBs3qjgG_eNSsxv8130_assertion description "[Bcl-x (L) and, to a lower extent, Mcl-1, are important anti-apoptotic factors in colorectal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106804.RAT7TqdUUDLpqZY0daBQmYbO-uKzenBs3qjgG_eNSsxv8130_provenance.
• NP106815.RAbykSnHAvZ13Vn5CCr47cfXxEpFqWJv5IVdws88H2KDw130_assertion description "[Genetic polymorphisms in UGT1A6 is associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106815.RAbykSnHAvZ13Vn5CCr47cfXxEpFqWJv5IVdws88H2KDw130_provenance.

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