Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Genetic+variations+of+SLCO1B3+and+UGT1A1+is+associated+serum+bilirubin+levels+in+Korean+population. assertion.
- assertion asSentence KappaB-Ras2+is+a+nuclear-cytoplasmic+small+GTPase+that+inhibits+NF-kappaB+activation+through+the+suppression+of+transcriptional+activation+of+p65%2FRelA. assertion.
- assertion asSentence Delta-1+can+enhance+myeloid+and+lymphoid+marrow-repopulating+ability+and+promote+the+generation+of+thymus-repopulating+T+cell+precursors. assertion.
- assertion asSentence Induces+a+NIH+3T3+cell+tranformed+phenotype+mediated+by+FGF+signaling. assertion.
- assertion asSentence The+stromal+cell-mediated+antiapoptotic+effect+on+B-+ALL+cells+is+mediated+by+Notch-3+and+-4+or+Jagged-1%2F-2+and+DLL-1+in+a+synergistic+manner. assertion.
- assertion asSentence Elevated+Tribbles+homolog+2-specific+antibody+levels+in+narcolepsy+patients. assertion.
- assertion asSentence Loss+of+p53+and+MCT-1+overexpression+synergistically+promote+chromosome+instability+and+tumorigenicity. assertion.
- assertion asSentence Overexpressed+wildtype+HIPK2+and+a+kinase+defective+mutant+of+HIPK2+directly+interact+with+RanBPM+in+the+nucleus+of+mammalian+cells. assertion.
- assertion asSentence Pc2+binds+to+and+colocalizes+with+homeodomain+interacting+protein+kinase+2+%28HIPK2%29+and+serves+as+a+SUMO+E3+ligase+for+this+kinase. assertion.
- assertion asSentence As+HIPK2+has+an+important+role+as+a+negative+regulator+of+gene+expression%2C+its+elimination+from+promoter-associated+repressor+complexes+allows+the+induction+of+a+substantial+fraction+of+hypoxia-induced+genes. assertion.
- assertion asSentence KLF15+is+a+negative+regulator+of+connective+tissue+growth+factor+expression+and+cardiac+fibrosis. assertion.
- assertion asSentence Kruppel-like+factor+15+activates+hepatitis+B+virus+gene+expression+and+replication. assertion.
- assertion asSentence Cosmc+is+an+endoplasmic+reticulum+%28ER%29-localized+adenosine+triphosphate+binding+chaperone+that+binds+directly+to+human+T-synthase. assertion.
- assertion asSentence HRPAP20+and+TIMELESS+as+promising+markers+of+tamoxifen+resistance+in+women+with+ER+alpha-positive+breast+tumors. assertion.
- assertion asSentence Methylation-mediated+silencing+of+TMS1%2FASC+confers+a+survival+advantage+to+ovarian+tumor+cells. assertion.
- assertion asSentence The+ASC%2FTMS1+gene+is+frequently+silenced+in+colorectal+cancer+due+to+promoter+hypermethylation. assertion.
- assertion asSentence The+inflammasome+component+apoptosis-associated+speck-like+protein+containing+a+caspase+recruitment+domain+%28ASC%29%2C+an+adapter+protein+within+the+NLRP3+inflammasome%2C+is+a+crucial+element+in+the+adjuvant+effect+of+MF59+combined+with+H5N1+subunit+vaccines. assertion.
- assertion asSentence Oligomerization+of+FHOD1+via+the+coiled-coil+motif+is+a+critical+parameter+for+its+biological+activities. assertion.
- assertion asSentence The+Diaphanous-related+Formin+FHOD1+associates+with+ROCK1+and+promotes+Src-dependent+plasma+membrane+blebbing. assertion.
- assertion asSentence IKKepsilon+and+TBK1+have+a+pivotal+role+in+coordinating+the+activation+of+IRF3+and+NF-kappaB+in+the+innate+immune+response. assertion.
- assertion asSentence TBK1+and+IKK+epsilon+directly+phosphorylate+the+C-terminal+domain+of+cRel+in+vitro+and+in+vivo+and+regulate+nuclear+accumulation+of+cRel. assertion.
- assertion asSentence C-Myc+negatively+regulates+and+Sp1+slightly+positively+regulate+BRD7+promoter+activity. assertion.
- assertion asSentence All-trans+retinoic+acid+enhances+brd7+gene+expression+as+HL-60+cells+differentiate. assertion.
- assertion asSentence Dosage+compensation+of+CTNNA3+and+p57KIP2+in+the+placenta+shares+a+conserved+regulatory+mechanism. assertion.
- assertion asSentence A+VE-cadherin-PAR3-alpha-catenin+complex+regulates+the+Golgi+localization+and+activity+of+cytosolic+phospholipase+A%282%29alpha+in+endothelial+cells. assertion.
- assertion asSentence Parallel+to+its+decreased+placental+expression%2C+an+augmented+membrane+shedding+of+PP13+contributes+to+the+increased+third+trimester+maternal+serum+PP13+concentrations+in+women+with+preterm+pre-eclampsia+and+HELLP+syndrome. assertion.
- assertion asSentence Elevated+B7-H1+expression+is+closely+associated+with+the+suppression+of+T+cell+immune+function+in+chronic+hepatitis+B+patients. assertion.
- assertion asSentence B7-H1+and+PD-1+expressions+in+patients+with+chronic+hepatitis+B+are+closely+associated+with+their+disease+status. assertion.
- assertion asSentence There+is+no+significant+difference+in+B7-H1+expression+on+T+cells+and+B+cells+between+chronic+hepatitis+B+patients+and+healthy+subjects. assertion.
- assertion asSentence PD-L1+expression+is+central+to+autoimmune+heart+and+lung+disease+in+lupus-susceptible+%28MRL%29+mice%2C+since+PD-L1-null+MRL+mice+succumb+to+autoimmune+myocarditis+and+pneumonitis+before+developing+renal+or+systemic+illness. assertion.
- assertion asSentence PD-1%2FPD-L1+expression+on+cells+from+asymptomatic+HTLV-1+carriers+and+ATLL+patients+in+comparison+with+cells+from+healthy+donors. assertion.
- assertion asSentence B7-H1+stimulation+activates+phosphorylation+of+JNK+and+c-jun+and+down-regulates+mitogen-activated+protein+kinases+1%2F2+and+akt+proto-oncogene+protein. assertion.
- assertion asSentence PD-L1+negatively+regulates+regulatory+T+cells+at+sites+of+chronic+hepatitis+c+infection+by+controlling+stat-5+phosphorylation. assertion.
- assertion asSentence The+PD-1%2FPD-L1+pathway+plays+an+important+role+in+modulating+immune+functions+in+multiple+sclerosis+patients. assertion.
- assertion asSentence PD-L1+upregulation+promotes+CD8+positive+T-cell+apoptosis+and+postoperative+recurrence+in+hepatocellular+carcinoma. assertion.
- assertion asSentence Costimulatory+PD-L1+expression+on+denrtic+cells+down+regulated+dendritic+cells-T+lymphocytes+activation+in+HCV-infected+patients. assertion.
- assertion asSentence Direct+suppression+of+HBV+replication+by+telbivudine+can+decrease+PD-1+and+PD-L1+expressions+and+restore+HBV-specific+CD8%2BT+cells. assertion.
- assertion asSentence During+dendritic+cell+differentiation+toll-like+receptor+agonists+induce+a+STAT-3-mediated+expression+of+PD-L1+and+favor+the+development+of+tolerogenic+antigen+presenting+cells. assertion.
- assertion asSentence Role+of+B7-H1+in+promoting+IL-10+production+in+hepatocellular+carcinoma+tissue. assertion.
- assertion asSentence Transgenic+PDL-1+blockade+initiated+prior+to+induction+of+listeriosis+infection+blunts+pathogen-specific+CD8-positive+T+cell+expansion+in+mice+with+targeted+interferon-gamma+defects. assertion.
- assertion asSentence The+level+of+RACGAP1+expression+is+sufficient+to+predict+the+early+recurrence+of+HCC. assertion.
- assertion asSentence ICBP90+is+involved+in+cell+proliferation+by+way+of+methylation-mediated+regulation+of+certain+genes. assertion.
- assertion asSentence Protein+kinase+C-CARMA3+signaling+axis+plays+an+essential+role+in+lysophosphatidic+acid-induced+ovarian+cancer+cell+in+vitro+invasion. assertion.
- assertion asSentence OLA1+suppresses+the+antioxidant+response+through+nontranscriptional+mechanisms. assertion.
- assertion asSentence Single+nucleotide+polymorphism+is+not+associated+with+chromosome+22+deletion+or+schizophrenia. assertion.
- assertion asSentence HIPK2+is+a+desumoylation+target+for+the+SUMO-specific+protease+SENP1+that+shuttles+between+the+cytoplasm+and+the+nucleus. assertion.
- assertion asSentence Genetic+polymorphism+of+the+human+ICOS+gene. assertion.
- assertion asSentence Modulation+of+immune+responses+by+ICOS-expressing+naturally+occurring+T+regulatory+cells+present+in+melanoma+tissue+depends+upon+costimulatory+signals+delivered+to+the+CD4-positive+CD25-negative+responder+cells+and+the+cytokine+milieu. assertion.
- assertion asSentence NPM-ALK+induces+expression+of+the+growth-promoting+receptor+ICOS. assertion.
- assertion asSentence Human+NPC1L1+can+functionally+substitute+for+the+Caenorhabditis+elegans+genes+ncr-1+and%2For+ncr-2. assertion.
- assertion asSentence NPC1L1+mediates+alpha-tocopherol+transport. assertion.
- assertion asSentence NPC1L1+gene+is+associated+with+plasma+total+and+LDL-C+levels+and+coronary+heart+disease+risk. assertion.
- assertion asSentence HHV-8+ORF57+interacts+with+RBM15+and+OTT3+to+promote+expression+of+viral+intronless+genes. assertion.
- assertion asSentence Schnyder+crystalline+corneal+dystrophy+mutations+affect+function%2C+ligand+binding+and+interaction+with+binding+partners%2C+like+apolipoproteins+E. assertion.
- assertion asSentence At+the+cellular+level%2C+two+different+calmodulin+antagonists+stimulated+calcium+release+from+the+endoplasmic+reticulum+through+SEC61+channels. assertion.
- assertion asSentence PAD1+is+co-located+with+filaggrin+within+the+filamentous+matrix+of+the+deeper+corneocytes+where+the+protein+is+deiminated. assertion.
- assertion asSentence Inactivation+and+disassembly+of+the+anaphase-promoting+complex+during+human+cytomegalovirus+infection+is+associated+with+degradation+of+the+APC5+and+APC4+subunits+and+does+not+require+UL97-mediated+phosphorylation+of+Cdh1. assertion.
- assertion asSentence Interaction+of+KLF6+and+Sp1%2C+together+with+their+binding+of+elements+in+exon+1+are+critical+events+in+initiation+of+transcription+of+the+tmsg-1+gene. assertion.
- assertion asSentence Ubiquilin+proteins+play+an+important+role+in+regulating+PS+protein+levels+in+cells. assertion.
- assertion asSentence Overexpression+of+ubiquilin+reduces+cell+death+in+HeLa+cells+and+primary+neurons+stably+expressing+green+fluorescent+protein-huntingtin+fusion+protein. assertion.
- assertion asSentence CIITA+-168A--%3EG+promoter+single+nucleotide+polymorphisms+are+not+associated+with+myasthenia+gravis. assertion.
- assertion asSentence Overexpression+of+RhoD+is+associated+with+multiple+myeloma. assertion.
- assertion asSentence Gene+expression+regulation+of+ZIPs+after+zinc+supplementation. assertion.
- assertion asSentence Polymorphisms+in+GLTSCR1+are+associated+with+the+development+of+oligodendrogliomas. assertion.
- assertion asSentence Molecular+bases+of+cyclic+and+specific+disulfide+interchange+between+human+ERO1alpha+protein+and+protein-disulfide+isomerase+%28PDI%29. assertion.
- assertion asSentence A+defect+in+Wiskott+Aldrich+CD4%2B+T+cells+is+due+to+reduction+in+T-bet+mRNA+expression+and+in+early+nuclear+recruitment+of+NFAT-1. assertion.
- assertion asSentence Genetic+variations+the+TBX21+promoter+region+contribute+to+susceptibility+to+HBV+infection+in+the+Chinese+population. assertion.
- assertion asSentence The+T-bet-IFN-gamma+axis+is+involved+in+the+pathogenesis+of+hairy-cell+leukemia. assertion.
- assertion asSentence Functional+polymorphisms+in+TBX21+are+associated+with+the+development+of+autoimmune+thyroid+diseases+and+prognosis+of+Graves%27+disease. assertion.
- assertion asSentence Cbl-directed+monoubiquitination+of+CIN85+is+involved+in+regulation+of+ligand-induced+degradation+of+EGF+receptors. assertion.
- assertion asSentence CIN85+%28SH3-domain+kinase+binding+protein+1%29+associates+with+TNF+receptor+1+via+Src+and+modulates+TNF-alpha-induced+apoptosis. assertion.
- assertion asSentence H-Ras+interacts+with+Spry2-binding+partners%2C+c-Cbl+and+CIN85%2C+in+a+Spry2-dependent+manner. assertion.
- assertion asSentence High+CIN85+is+associated+with+the+development+and+progression+of+head+and+neck+squamous+cell+carcinoma. assertion.
- assertion asSentence HOX11L2+expression+defines+a+clinical+subtype+of+pediatric+T-ALL+associated+with+poor+prognosis. assertion.
- assertion asSentence The+Significance+of+HOX11L2%2FTLX3+expression+in+children+with+T-cell+acute+lymphoblastic+leukemia+treated+on+Children%27s+Cancer+Group+protocols. assertion.
- assertion asSentence Both+L+ferritin+IRE+and+ferroportin+mutations+can+account+for+isolated+hyperferritinemia. assertion.
- assertion asSentence Ferroportin+is+a+pivotal+protein+in+breast+biology+and+a+strong+and+independent+predictor+of+prognosis+in+breast+cancer. assertion.
- assertion asSentence Placental+FPN1+expression+is+not+dependent+on+the+iron+regular+element%2Firon+regular+protein+regulation. assertion.
- assertion asSentence Mutations+in+the+SLC40A1+gene+is+associated+with+hemochromatosis. assertion.
- assertion asSentence A+functional+role+for+EMR2+in+the+modulation+of+neutrophil+activation+during+inflammation. assertion.
- assertion asSentence The+downregulation+of+the+regulator+of+Ca2%2B+homeostasis+NCX3+by+Ca2%2B-regulated+DREAM+is+a+striking+example+of+the+autoregulatory+property+of+the+Ca2%2B+signal+in+neurons. assertion.
- assertion asSentence The+I%28to%29+activator+NS5806+modified+Kv4.3%2FKChIP2+gating+in+several+ways+that+inhibit+current. assertion.
- assertion asSentence The+%22structurally+minimal%22+isoform+KChIP2d+modulates+recovery+of+K%28v%294.3+N-terminal+deletion+mutant+Delta2-39. assertion.
- assertion asSentence ZNRD1+gene+displays+high+expression+in+VCR+resistant+gastric+cancer+cells. assertion.
- assertion asSentence DC-SIGN+expression+in+B-cell+lines+dramatically+enhances+viral+internalization. assertion.
- assertion asSentence 336G%2FA+single+nucleotide+polymorphisms+in+the+promoter+region+and+insertion%2Fdeletion+polymorphisms+in+the+%22neck%22+region+of+CD209%2C+are+not+relevant+risk+factors+for+developing+tuberculosis+in+Northwestern+Colombian+individuals. assertion.
- assertion asSentence DC-SIGN+is+selective+in+its+recognition+of+specific+types+of+fucosylated+glycans+and+subsets+of+oligomannose-+and+complex-type+N-glycans. assertion.
- assertion asSentence DC-SIGN+is+not+an+Ebola+virus+receptor+but%2C+rather%2C+is+an+attachment-promoting+factor+that+boosts+entry+into+B+cell+lines. assertion.
- assertion asSentence DC-sign%2B+CD163%2B+macrophages+expressing+hyaluronan+receptor+LYVE-1+are+located+within+chorion+villi+of+the+placenta. assertion.
- assertion asSentence DC-SIGN+is+involved+in+the+interaction+of+dendritic+cells+with+SW1116+colorectal+carcinoma+cells+through+the+recognition+of+aberrantly+glycosylated+forms+of+Lewis+a%2FLewis+b+glycans. assertion.
- assertion asSentence DC-SIGN+enhances+cell+infection+by+glycosylated+West+Nile+virus. assertion.
- assertion asSentence There+is+no+significant+correlation+between+the+genetic+polymorphism+of+DC-SIGNR+and+HCV-RNA+genotypes. assertion.
- assertion asSentence It+is+a+major+bacterial+sensor+molecule+expressed+in+antigen-presenting+cells+and+its+polymorphism+reflects+its+role+in+establishment+of+leprosy. assertion.
- assertion asSentence Glycan+modification+of+antigens+and+targeting+to+DC-SIGN+enhance+both+CD4+and+CD8+T+cell+responses. assertion.
- assertion asSentence The+rs4804803+single+nucleotide+polymorphism+in+the+CD209+promoter+contributed+to+susceptibility+to+dengue+infection+and+complication+of+dengue+hemorrhagic+fever. assertion.
- assertion asSentence A+combination+of+human+CD209+-336G+allele+and+M.+tuberculosis+Beijing+genotype+leads+more+frequently+to+the+lethal+outcome+in+pulmonary+TB+male+patients+in+Russian+%28Caucasian%29+population. assertion.
- assertion asSentence EHD2+regulates+trafficking+from+the+plasma+membrane+by+controlling+Rac1+activity. assertion.
- assertion asSentence There+is+a+high+frequency+of+the+LAGE-1+gene+allele+with+SNPs+in+coding+regions+in+cancer+patients. assertion.
- assertion asSentence By+sequestering+cyclin+A%2FCdk2%2C+SCAPER+is+capable+of+directing+the+activity+of+this+kinase+complex+away+from+the+nucleus+and+regulating+cyclin+A%2FCdk2+equilibrium+in+distinct+subcellular+compartments. assertion.
- assertion asSentence Expression+of+p53R2%2C+newly+p53+target+in+oral+normal+epithelium%2C+epithelial+dysplasia+and+squamous+cell+carcinoma. assertion.