Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP106816.RAVDoYKWxCGDs6UU7X_Kl5hM3mQTpwt4DVymL1Q4Bneeo130_assertion description "[Expression of Robo1 is mainly in tumor cells, whereas Robo4 is primarily in endothelial cells of tumor vessels/, the Robo proteins provide potential target structures for the anti-tumorigenic and anti-angiogenic therapy of colorectal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106816.RAVDoYKWxCGDs6UU7X_Kl5hM3mQTpwt4DVymL1Q4Bneeo130_provenance.
- NP106822.RAYn7ZeZDphwFMoy4UO5RC8BI6vRZO-vXwHVhkF-_FyCs130_assertion description "[Decrease of 11betaHSD1 mRNA abundance and enzyme activity is associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106822.RAYn7ZeZDphwFMoy4UO5RC8BI6vRZO-vXwHVhkF-_FyCs130_provenance.
- NP106823.RARgkluMN-jnxJY6lgXt2IMdqD4cqDwuneRI3rOcvcX1Q130_assertion description "[Fecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106823.RARgkluMN-jnxJY6lgXt2IMdqD4cqDwuneRI3rOcvcX1Q130_provenance.
- NP106825.RAcba2o2isnhk44y5l8mTALLDtkB4_Oh536Q6dgpHhKxk130_assertion description "[Single nucleotide polymorphism in SMAD7 is associated with colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106825.RAcba2o2isnhk44y5l8mTALLDtkB4_Oh536Q6dgpHhKxk130_provenance.
- NP106828.RAZBJzzkUFhgpNx4aFdg7vm1gewfbtVhUimmlxF6DqhhQ130_assertion description "[Involvement in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106828.RAZBJzzkUFhgpNx4aFdg7vm1gewfbtVhUimmlxF6DqhhQ130_provenance.
- NP106831.RATp14y4k1sPxU2tmKdfkTdlR0tYqnFbPMy35TUrnU0kM130_assertion description "[VEGF isoforms and mutations in human colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106831.RATp14y4k1sPxU2tmKdfkTdlR0tYqnFbPMy35TUrnU0kM130_provenance.
- NP106832.RAR2_OrGKcOrB5KxZUpO8RhcWLiY_FVNL4Nb09oUbLn_U130_assertion description "[the VEGF gene polymorphisms may be associated with the susceptibility or clinicopathologic features of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106832.RAR2_OrGKcOrB5KxZUpO8RhcWLiY_FVNL4Nb09oUbLn_U130_provenance.
- NP106834.RAehTfawORcGO0HSJMWgtdjh0ZCrYRqXKjhhAuIogkohQ130_assertion description "[VEGF is associated with the development and prognosis of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106834.RAehTfawORcGO0HSJMWgtdjh0ZCrYRqXKjhhAuIogkohQ130_provenance.
- NP106835.RAXlA1zfurXH5fEPJKQXQO6JNDLPTahhqMEzUP7l5JpMw130_assertion description "[prognostic value of matched preoperative serum and plasma vascular endothelial growth factor concentrations in patients with colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106835.RAXlA1zfurXH5fEPJKQXQO6JNDLPTahhqMEzUP7l5JpMw130_provenance.
- NP106836.RAUnvYs6RQHesopHi8KR_yLcafTHotwIRmHGs6mM8S1-I130_assertion description "[VEGF took part in development and progression of colorectal carcinomas and that Id-1 was associated with regulations of VEGF ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106836.RAUnvYs6RQHesopHi8KR_yLcafTHotwIRmHGs6mM8S1-I130_provenance.
- NP106837.RAaX8eUzizL8prxxf_0pBf_UuvYT-h7jw3DkUSSb8jrnI130_assertion description "[Patients with high postoperative VEGF-A should be scanned for metastases in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106837.RAaX8eUzizL8prxxf_0pBf_UuvYT-h7jw3DkUSSb8jrnI130_provenance.
- NP106841.RARS8EFtBHrmhumNwrXWZeY9n7zzBp0sslXXoQO954qrU130_assertion description "[The results suggest that I3C represses cell proliferation through up-regulation of NAG-1 and that ATF3 may play a pivotal role in DIM-induced NAG-1 expression in human colorectal cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106841.RARS8EFtBHrmhumNwrXWZeY9n7zzBp0sslXXoQO954qrU130_provenance.
- NP106843.RAWNxcXi6LAeQYcuXsT21u8DZ0zxQsKRae4y3MPKAgaUA130_assertion description "[Loss of CDX2 and CK20 is more frequently encountered in mismatch repair-deficient colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106843.RAWNxcXi6LAeQYcuXsT21u8DZ0zxQsKRae4y3MPKAgaUA130_provenance.
- NP106845.RAZpWRCsy-AFsdEnkaok0ErPkpSUXTAJPwZpRxgyTVzpU130_assertion description "[expression in lymph nodes correlates with poor prognosis in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106845.RAZpWRCsy-AFsdEnkaok0ErPkpSUXTAJPwZpRxgyTVzpU130_provenance.
- NP106848.RARy-VdTlo8TjPgnFQ2CtUjZ1XMmYzK-cSQPhsUxdprwk130_assertion description "[Elevated ADIPOR1 expression is associated with colorectal carcinomas but not in gastrointestinal stromal tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106848.RARy-VdTlo8TjPgnFQ2CtUjZ1XMmYzK-cSQPhsUxdprwk130_provenance.
- NP106850.RAf83UEKapxPg4Mj1qTZ_zJ6o6lzcCUbXC-lfgb9vSOPM130_assertion description "[Reg IV is a potent activator of the EGF receptor/Akt/AP-1 signaling pathway in colorectal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106850.RAf83UEKapxPg4Mj1qTZ_zJ6o6lzcCUbXC-lfgb9vSOPM130_provenance.
- NP106854.RAUzc_Kysc9HA3hOHgKCN9UkYWK-9uKorXqXL4lSvyioc130_assertion description "[PTGSw2 gene expression was significantly higher in colorectal cancer patietnts than in healthy volunteers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106854.RAUzc_Kysc9HA3hOHgKCN9UkYWK-9uKorXqXL4lSvyioc130_provenance.
- NP106855.RASpDtwR1T2znODRu84OSkpnIEGLdZRzKAElcThlVpFcY130_assertion description "[the transcriptional activity of the COX-2 gene in colorectal cancer cells and the identification of regulatory promoter elements ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106855.RASpDtwR1T2znODRu84OSkpnIEGLdZRzKAElcThlVpFcY130_provenance.
- NP106867.RAbCLZiPPEzF1EhbmBMLRA5e_NRHKsIpHCk-xEGFLMSGw130_assertion description "[Incidence of K-ras mutation and frequencies of COX-2 and gastrin overexpressand protruded type ion are high in laterally spreading granular colorectal tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106867.RAbCLZiPPEzF1EhbmBMLRA5e_NRHKsIpHCk-xEGFLMSGw130_provenance.
- NP106868.RAYT07S15VvhfZ20zqhsdvh5ptV57VamX8EDHKLe2VahU130_assertion description "[Our objectives were to determine the relationship between cyclooxygenase-2 and haematogenous spread to bone marrow in patients with colorectal carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106868.RAYT07S15VvhfZ20zqhsdvh5ptV57VamX8EDHKLe2VahU130_provenance.
- NP106870.RAVcs869B5N1M-PTYZ5-Av_E8HsLuCF4xx_AjjlAfQchs130_assertion description "[Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106870.RAVcs869B5N1M-PTYZ5-Av_E8HsLuCF4xx_AjjlAfQchs130_provenance.
- NP106872.RAcr1ffXy-ldfH5u_VjZkfMxHZtiqD8KakUMeIP2484Fo130_assertion description "[LPA acts upstream of various receptor tyrosine kinases and COX-2, and thus may act as a potent stimulator of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106872.RAcr1ffXy-ldfH5u_VjZkfMxHZtiqD8KakUMeIP2484Fo130_provenance.
- NP106881.RAUWYwYKywhXBB1oZ_eDmFIIbIMI0YkVirkRTTnP_tpOk130_assertion description "[PTEN is mutated in a significant subgroup of colorectal carcinomas, and all novel mutations found were in tumors harboring wild-type TP53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106881.RAUWYwYKywhXBB1oZ_eDmFIIbIMI0YkVirkRTTnP_tpOk130_provenance.
- NP106886.RAXW-wayo4MV_dLFIJZrdXiEo-gM_SHIgIggdRwGWFM1s130_assertion description "[This study provides some support for polymorphic variation in CYP1A2 and CYP1B1 playing a role in colorectal cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106886.RAXW-wayo4MV_dLFIJZrdXiEo-gM_SHIgIggdRwGWFM1s130_provenance.
- NP106888.RATuAm-u5qUCpC6mXSJxgczWPdx-6sEqgE5XUlIlIl_08130_assertion description "[The 1462V and Msp1 polymorphisms in CYP1A1 may be an additional susceptibility factor for disease expression in Lynch syndrome because they modify colorectal neoplasm age of onset by 4 years ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106888.RATuAm-u5qUCpC6mXSJxgczWPdx-6sEqgE5XUlIlIl_08130_provenance.
- NP106890.RAf99p6KvueiC_tkHPHsvutxpAkv-PzVqh4CarpP2Nhr8130_assertion description "[Red meat intake was associated with increased colorectal cancer regardless of genotype, but the CYP1A1 combined variant modified association between meat doneness and cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106890.RAf99p6KvueiC_tkHPHsvutxpAkv-PzVqh4CarpP2Nhr8130_provenance.
- NP106891.RAcb9JxRYxWJsDX8LUbjehtezpZ820wETHEAmpO0FUaWc130_assertion description "[Risk for colorectal cancer and selected red and white meat mutagen indices and the use of white meat drippings, or fried white meat variables was more evident within select combinations of the CYP1A1 genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106891.RAcb9JxRYxWJsDX8LUbjehtezpZ820wETHEAmpO0FUaWc130_provenance.
- NP106892.RAQYCigdX_PCIkrzSBVuIwi9iWOgjZHG2Kt7vfV70B5Jw130_assertion description "[incidence of the polymorphism A-- > G (Ile462Val, exon 7) in colorectal cancer patients and the correlation of this polymorphism with others risk factors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106892.RAQYCigdX_PCIkrzSBVuIwi9iWOgjZHG2Kt7vfV70B5Jw130_provenance.
- NP106894.RAdYrUObEogRuPxZSTtnZLbFz_ue40UI5jDQ3lJkGgyjQ130_assertion description "[comparison of the expression of HIF-1alpha and GLUT-1 with various clinicopathological features of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106894.RAdYrUObEogRuPxZSTtnZLbFz_ue40UI5jDQ3lJkGgyjQ130_provenance.
- NP106899.RAexhmF_tsqbSZ0MUU4_87dFKi-XIgXdU_mNJH1CCqWek130_assertion description "[SKP2 and the ubiquitin-proteasome pathway may be potential targets for therapeutic intervention for treatment of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106899.RAexhmF_tsqbSZ0MUU4_87dFKi-XIgXdU_mNJH1CCqWek130_provenance.
- NP106901.RAYWSUYDlB53K51i1F23bd4toACE7nAIYCTTJxvYNfm_E130_assertion description "[Data show that enhanced expression of matrix metalloproteinases 2 was detected in colorectal cancer patients with distant metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106901.RAYWSUYDlB53K51i1F23bd4toACE7nAIYCTTJxvYNfm_E130_provenance.
- NP106907.RAZ7dlkncvm25QuikdHRnpDx4voNSs49lJG7Z1f6wdD5k130_assertion description "[ADAMTSL3 is expressed in numerous tissues, suggesting a broader regulatory role than in colorectal epithelium alone, and that colorectal cancer has both structural mutations as well as decreased expression of ADAMTSL3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106907.RAZ7dlkncvm25QuikdHRnpDx4voNSs49lJG7Z1f6wdD5k130_provenance.
- NP106908.RASoJYeL10Hf1CDrAEpHBQyQ79ndHA7YRl4ThCKgL-fxk130_assertion description "[in colorectal cancer and gastric cancer promoter hypermethylation and transcriptional silencing are frequent for GATA-4 and -5 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106908.RASoJYeL10Hf1CDrAEpHBQyQ79ndHA7YRl4ThCKgL-fxk130_provenance.
- NP106917.RAeOs1r6tu776BMQSnUr2R0s_iUoVESTBPRzHSUJ5PtUA130_assertion description "[Expression profiling and regulation of liver metastases in colorectal cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106917.RAeOs1r6tu776BMQSnUr2R0s_iUoVESTBPRzHSUJ5PtUA130_provenance.
- NP106918.RAc1rDhVIM1LCe2HzSkjLhdseZpCzltd5dee0H5S37VVI130_assertion description "[active transcription machinery for DPYD is present in RKO colorectal cancer cells, but promoter binding of Sp1, a transactivator of DPYD, was inhibited, which on subsequent examination was shown to be associated with dense promoter methylation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106918.RAc1rDhVIM1LCe2HzSkjLhdseZpCzltd5dee0H5S37VVI130_provenance.
- NP106925.RAcE_j0jA-nmsZG-ibdFWwlAZMq7ZeP2nxWOS7OeAFtAY130_assertion description "[activation in colorectal cancer triggered by the plasminogen-activating system ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106925.RAcE_j0jA-nmsZG-ibdFWwlAZMq7ZeP2nxWOS7OeAFtAY130_provenance.
- NP106927.RAbKER9lZ-hgeiA-4sfwyxtGAwH4vNLM8mGQyxD7Ri3vI130_assertion description "[RKIP loss by hypermethylation of its promoter could have a significant influence on colorectal cancer aneuploidy, which might explain its association with metastatic progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106927.RAbKER9lZ-hgeiA-4sfwyxtGAwH4vNLM8mGQyxD7Ri3vI130_provenance.
- NP106929.RAafHBmLrx_z3LeLmQ4z34fCZidXA470gBx50f_dQLn4U130_assertion description "[the miR-135 family regulates APC in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106929.RAafHBmLrx_z3LeLmQ4z34fCZidXA470gBx50f_dQLn4U130_provenance.
- NP106932.RAW6vX02tKdc4kHdTVfgndHcA0ez4VuF9-kQJwzXvKEfQ130_assertion description "[Aurora-A amplification was strongly associated with a high fractional allelic loss score (p = 0.0001), but not with microsatellite instability, nor with the promoter methylation phenotype in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106932.RAW6vX02tKdc4kHdTVfgndHcA0ez4VuF9-kQJwzXvKEfQ130_provenance.
- NP106936.RAUUoFnVuLr5LVz5zxKMHFk5hGzOHj0R8FBd92Y_TkiAE130_assertion description "[upregulation of TXNDC5 are involved in the early development of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106936.RAUUoFnVuLr5LVz5zxKMHFk5hGzOHj0R8FBd92Y_TkiAE130_provenance.
- NP106949.RAR7tqikS4kqznO5RWgt1fN9StjNz0Bv00CFgU458zkL8130_assertion description "[Our results suggest that ECA39 is a dominant predictive factor for distant metastasis in patients with advanced colorectal cancer (CRC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106949.RAR7tqikS4kqznO5RWgt1fN9StjNz0Bv00CFgU458zkL8130_provenance.
- NP106952.RAVO8SlGfPTR-wz-8eiH2AzBBL1xivh5Tz_PLqrMqLGLE130_assertion description "[The expression of endocan is down-regulated in colorectal cancer and is positively correlated with the tissue differentiation in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106952.RAVO8SlGfPTR-wz-8eiH2AzBBL1xivh5Tz_PLqrMqLGLE130_provenance.
- NP106953.RAW1hF5NBY6KacwE3MxjoltjrhZ8rcB_3t626QvpxMp68130_assertion description "[SOX17 silencing due to promoter hypermethylation is an early event during tumorigenesis and may contribute to aberrant activation of Wnt signaling in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106953.RAW1hF5NBY6KacwE3MxjoltjrhZ8rcB_3t626QvpxMp68130_provenance.
- NP106969.RAZZtr2oRyn8PLG6svDJDfjXBVchsd6pTWxx9SPNGi6pE130_assertion description "[APC and K-ras, but not CTNNB1 mutations have roles in regulation of expression of hMLH1 in sporadic colorectal carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106969.RAZZtr2oRyn8PLG6svDJDfjXBVchsd6pTWxx9SPNGi6pE130_provenance.
- NP106970.RAcHn7YiMXzrAI9Ag_ojtVjCBepFHqeZHxJKUJ2XGLIWU130_assertion description "[Some smoking characteristics, i.e.being an ex-smoker, frequency and inhalation, may be associated with risk for colorectal cancer characterized by the wild-type KRAS gene, especially in men.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106970.RAcHn7YiMXzrAI9Ag_ojtVjCBepFHqeZHxJKUJ2XGLIWU130_provenance.
- NP106978.RAY0maeEE5_GEQnH9pup0R34k19Q1fHsBYF27tgZKL9sU130_assertion description "[Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106978.RAY0maeEE5_GEQnH9pup0R34k19Q1fHsBYF27tgZKL9sU130_provenance.
- NP106983.RAV3GuS8JkIhdUQQLJzF-au4n59rdHBSyJe7bD3BP8nrs130_assertion description "[This study demonstrates the occurrence of cytochrome P450 3A-dependent metabolism in colorectal cancer tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106983.RAV3GuS8JkIhdUQQLJzF-au4n59rdHBSyJe7bD3BP8nrs130_provenance.
- NP106992.RAQzl_8L07ObEhIZyFJ37hy75_u1-XaM_yluKOcm59Qmo130_assertion description "[A study evaluating 2 polymorphisms of CX3CR1 in colorectal cancer (CRC) in CRC to find out whether they occur more often in patients with CRC than in non-CRC individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106992.RAQzl_8L07ObEhIZyFJ37hy75_u1-XaM_yluKOcm59Qmo130_provenance.
- NP106995.RAagqyRtqT9nRo39xaeXUFR26EiUwVyhELPqnveU4FrY8130_assertion description "[The frequent expression and coexpression of Fas, FasL and c-FLIP in colorectal carcinoma implicates c-FLIP as an inhibitor of the Fas-FasL-induced death pathway in these tumours.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106995.RAagqyRtqT9nRo39xaeXUFR26EiUwVyhELPqnveU4FrY8130_provenance.
- NP106997.RAYjmb0U9PfZuBvgFXRhaXVYT8fp7AGaAEaYiop5G6__s130_assertion description "[Fas downregulation and a consequential increased resistance to FasL-triggered apoptosis resulting from upregulated MMP-7 in colorectal cancer cells could be a key mechanism for their escape from the immune surveillance ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP106997.RAYjmb0U9PfZuBvgFXRhaXVYT8fp7AGaAEaYiop5G6__s130_provenance.
- NP107000.RAcXmj5HyXt9oFf4ADYd0MkTKW-fVtuGTNFfvxnBZ1cKY130_assertion description "[Data strongly indicate that an increment of soluble FAS/soluble FASL ratio after treatment could be an excellent marker of chemosensitivity in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107000.RAcXmj5HyXt9oFf4ADYd0MkTKW-fVtuGTNFfvxnBZ1cKY130_provenance.
- NP107002.RAcvikS5fe0LK-3Vs9X1m8yqSQIS673icO9l2-RCs5-TQ130_assertion description "[miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107002.RAcvikS5fe0LK-3Vs9X1m8yqSQIS673icO9l2-RCs5-TQ130_provenance.
- NP107007.RAZlc2eoagiJhwlx6ywT0hytiEdiBO3JGzUpkwKXOjbrw130_assertion description "[although the RFC1 80G > A and FOLH1 1561C > T polymorphisms may influence folate status, they are not likely to have a major independent role in the development of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107007.RAZlc2eoagiJhwlx6ywT0hytiEdiBO3JGzUpkwKXOjbrw130_provenance.
- NP107012.RAT7CJTNGYr8QC248q28rQA4RXhUa6RXztYfppkyKIvvQ130_assertion description "[This study provides some support for polymorphic variation in CYP1A2 and CYP1B1 playing a role in colorectal cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107012.RAT7CJTNGYr8QC248q28rQA4RXhUa6RXztYfppkyKIvvQ130_provenance.
- NP107017.RAShjlSdiPp_fmsg5k7ujLKtDR0rErdojvqKUuRAbRDdA130_assertion description "[data suggest that RhoGDI may promote colorectal cancer progression and metastasis by stimulating tumor cell growth and migration ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107017.RAShjlSdiPp_fmsg5k7ujLKtDR0rErdojvqKUuRAbRDdA130_provenance.
- NP107018.RAV75YPgqkwGjsKccQZgLuVzX8qVqSFXaQS9kVPaN2gKo130_assertion description "[Overexpression of arginase is associated with colorectal carcinoma and colorectal liver metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107018.RAV75YPgqkwGjsKccQZgLuVzX8qVqSFXaQS9kVPaN2gKo130_provenance.
- NP107027.RAQFRgJjis7nrHvahv043k8gvH7KXPXz2NFEquuaWysk0130_assertion description "[Selesctive inhibitors potentiate apoptosis induction by sulindac sulfide, an NSAID, suggesting a novel strategy for the prevention or treatment of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107027.RAQFRgJjis7nrHvahv043k8gvH7KXPXz2NFEquuaWysk0130_provenance.
- NP107030.RAXjk6IyX-9knSTUStkawkOFeSyqHw1g5O3A7SqOoxH9M130_assertion description "[Strong prognostic impact of HDAC isoforms in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107030.RAXjk6IyX-9knSTUStkawkOFeSyqHw1g5O3A7SqOoxH9M130_provenance.
- NP107031.RAQAVJnFnywojO01GMkkO-7PxydrdIG8blX19grcGWCCU130_assertion description "[All colorectal neoplasms samples showed hypermethylation in the promoter region of SFRP1 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107031.RAQAVJnFnywojO01GMkkO-7PxydrdIG8blX19grcGWCCU130_provenance.
- NP107032.RAUAKaLa0iXgkmv-d999c46TE5ddCQioYxNXmoA_k2RRM130_assertion description "[In contrast to other sFRP family members, sFRP-4 expression appears to be upregulated in colorectal carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107032.RAUAKaLa0iXgkmv-d999c46TE5ddCQioYxNXmoA_k2RRM130_provenance.
- NP107036.RAcm71OoXHKB_X02qWl_ON7TYmkjRK-9-gHb_uTDxX_wA130_assertion description "[study verified reduced expressions of adenomatous polyposis coli and E-cadherin proteins in colorectal cancer cells and suggests that normal protein expressions in benign epithelium are progressively and independently lost in sporadic colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107036.RAcm71OoXHKB_X02qWl_ON7TYmkjRK-9-gHb_uTDxX_wA130_provenance.
- NP107042.RAal5N9KCYvdZxtVNGCUnbys9WILQG3x8esFRdysz1f-s130_assertion description "[High nuclear expression of c-myc is correlated with locally advanced colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107042.RAal5N9KCYvdZxtVNGCUnbys9WILQG3x8esFRdysz1f-s130_provenance.
- NP107044.RAb7TkPrjU6s7Jd57t3ezxKzUyWzabGfz9cF9Bf1qyy58130_assertion description "[Tiam1 is overexpressed in a subset of human colorectal tumors/affects multiple properties associated with acquisition of the metastatic phenotype & may represent a marker of colon tumor progression & metastasis in a subset of tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107044.RAb7TkPrjU6s7Jd57t3ezxKzUyWzabGfz9cF9Bf1qyy58130_provenance.
- NP107049.RAdZUK26IvIxo4FZYsQ3PxjuxS2ZvhGzolS4EBB9SxY_Y130_assertion description "[NFkappaB activation mediated by loss of E-cadherin may represent an essential, even initial event in colorectal neoplasm metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107049.RAdZUK26IvIxo4FZYsQ3PxjuxS2ZvhGzolS4EBB9SxY_Y130_provenance.
- NP107061.RAQfjavczDbBYakTupwdm-CrPPCBvN044ctjwEkubEISY130_assertion description "[COUP-TFII may represent a biomarker for good prognosis in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107061.RAQfjavczDbBYakTupwdm-CrPPCBvN044ctjwEkubEISY130_provenance.
- NP107062.RAckbtbJMkxbay-mn0knldFEniOqEC3LpX3k56EcLd-VE130_assertion description "[there is a close correlation between CLN2 and CLN1 expression and colorectal carcinoma progression and metastasis and suggest that they may be potential molecular targets ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107062.RAckbtbJMkxbay-mn0knldFEniOqEC3LpX3k56EcLd-VE130_provenance.
- NP107066.RATirkNG8VmwCey_KooW6SP3XL910LzHz6gigGauBvxy0130_assertion description "[ACO2 is often deleted in colorectal cancer but is unlikely to be the true target of the deletions ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107066.RATirkNG8VmwCey_KooW6SP3XL910LzHz6gigGauBvxy0130_provenance.
- NP107070.RAUQY8dQ0ttmEn_vO3-m6C6GZzbxHoApDwJR1LjBrkdJM130_assertion description "[Mutations of rabphillin-3A-like gene is associated with colorectal cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107070.RAUQY8dQ0ttmEn_vO3-m6C6GZzbxHoApDwJR1LjBrkdJM130_provenance.
- NP107075.RAe9mA3yAdLhEmV5EBFz_WrllmZ0afBZAl3raf6G08eRk130_assertion description "[KLF6 gene may be one of the candidate tumor suppressor genes in colorectal cancers and that genetic alteration of the KLF6 gene might play a role in the development of colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107075.RAe9mA3yAdLhEmV5EBFz_WrllmZ0afBZAl3raf6G08eRk130_provenance.
- NP107076.RAdATjJCcS0XeAUPFZSKyGUTZLJY6SSeprsVdlhgZ7jjY130_assertion description "[KLF6 and p53 mutations are involved in the development of nonpolypoid colorectal carcinoma, whereas K-ras and B-raf mutations are not ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107076.RAdATjJCcS0XeAUPFZSKyGUTZLJY6SSeprsVdlhgZ7jjY130_provenance.
- NP107077.RAR-LCx7YI7DotsmbO6r_nVTkuayVH_e9m61ha0ajPsbQ130_assertion description "[Deregulation of KLF6 by a combination of allelic imbalance and mutation may play a role in the development of colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107077.RAR-LCx7YI7DotsmbO6r_nVTkuayVH_e9m61ha0ajPsbQ130_provenance.
- NP107080.RAY_jr9k_qjZGy8G7vaPDYCHXQCgolBCn2JaLdT49L-CE130_assertion description "[Increased legumain expression is associated with primary colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107080.RAY_jr9k_qjZGy8G7vaPDYCHXQCgolBCn2JaLdT49L-CE130_provenance.
- NP107085.RAT8Cl7j-HHnjMvXh4FWbwUkBZtdUyZJruL7HXCTkec5s130_assertion description "[c-FLIP inhibits apoptosis in response to chemotherapy in colorectal cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107085.RAT8Cl7j-HHnjMvXh4FWbwUkBZtdUyZJruL7HXCTkec5s130_provenance.
- NP107090.RAS2XXxQ3VoSgfnDetu-kW6BqTjyKUjrTYfxJcXph0MBs130_assertion description "[Common polymorphisms in this protein are associated with increased risk of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107090.RAS2XXxQ3VoSgfnDetu-kW6BqTjyKUjrTYfxJcXph0MBs130_provenance.
- NP107092.RAT0U-ieLptDpuglSSXHt0QwtjoZoUYvqDnQt-j4_ThcA130_assertion description "[mucin and MUC1 have roles in progression of hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107092.RAT0U-ieLptDpuglSSXHt0QwtjoZoUYvqDnQt-j4_ThcA130_provenance.
- NP107093.RAb8kP-nn3aNeM-dF5aBSDEcf0WbY_UMnF7cp4GASu1nc130_assertion description "[MUC1 and beta-catenin have a role in progression and invasiveness of colorectal carcinomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107093.RAb8kP-nn3aNeM-dF5aBSDEcf0WbY_UMnF7cp4GASu1nc130_provenance.
- NP107096.RAe9sPBiNO1Ro9gi5Pmpw6hdNr4EZz9r2AjmME1hBag9U130_assertion description "[Data show that HECA may be an early-stage classifier of colorectal cancer that can discriminate between late- and early-stage disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107096.RAe9sPBiNO1Ro9gi5Pmpw6hdNr4EZz9r2AjmME1hBag9U130_provenance.
- NP107097.RAQT79XwjMvpoCfaLJ_HwJAC76AnfTpbWeu47AlftWZG0130_assertion description "[TNFR2 and TNFR2/R7 are dysregulated and have roles in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107097.RAQT79XwjMvpoCfaLJ_HwJAC76AnfTpbWeu47AlftWZG0130_provenance.
- NP107099.RAVENVhFB7U_yl1GRmPTEJWXArHEhr7P9zASfk5urPOi0130_assertion description "[SnoN and Ski were overexpressed both in adenomas with severe dysplasia and colorectal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107099.RAVENVhFB7U_yl1GRmPTEJWXArHEhr7P9zASfk5urPOi0130_provenance.
- NP107108.RAfBQFNDYDtZxFb7rc4ZAtRXyg8BW6zb1ayTccKa4AHw8130_assertion description "[IKKalpha involved in COX-2 induction in colorectal tumors ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107108.RAfBQFNDYDtZxFb7rc4ZAtRXyg8BW6zb1ayTccKa4AHw8130_provenance.
- NP107111.RAW_fU7cAqq1cTzJ9b1yezyG73PzUCeViuv-CfWg0gFdw130_assertion description "[Eag1 protein and mRNA are aberrantly expressed in colorectal cancer and occasionally expressed in colorectal adenoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107111.RAW_fU7cAqq1cTzJ9b1yezyG73PzUCeViuv-CfWg0gFdw130_provenance.
- NP107112.RAQYh4d1o6Hlftm9Xt8VO24mb5vKb0SuUK-JGpAQaCZGc130_assertion description "[E-cadherin promoter is subject to epigenetic control in colorectal ulceration and plays a role in the progression from chronic inflammation to colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107112.RAQYh4d1o6Hlftm9Xt8VO24mb5vKb0SuUK-JGpAQaCZGc130_provenance.
- NP107113.RAW34flbpzd16m6aSf3KkD8GkttEW-WmZEzeGLQwKx72c130_assertion description "[association between SNPs in the promoter of the TNF-alpha gene and ulcerative colitis and colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107113.RAW34flbpzd16m6aSf3KkD8GkttEW-WmZEzeGLQwKx72c130_provenance.
- NP107114.RAX3o7R0vGlNQFI9VN9sXA_m83gro2c_2fzGf_-iAp2AQ130_assertion description "[Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107114.RAX3o7R0vGlNQFI9VN9sXA_m83gro2c_2fzGf_-iAp2AQ130_provenance.
- NP107119.RAe0ziholyqEpgSN46CSEVIKS82eQ7QdDfR0UTEkn7_a8130_assertion description "[Tyrosine phosphorylation of ZO-1 leads to down-regulation of the function of ZO-1 and dedifferentiation of the glands in colorectal cancers/phenomena contribute to liver metastases, & redifferentiation of the glands occurs in the liver metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107119.RAe0ziholyqEpgSN46CSEVIKS82eQ7QdDfR0UTEkn7_a8130_provenance.
- NP107126.RAVFrdqy-3PyZZweV15u0rxhAX6EDOJ34QlUcxA9VV-Ao130_assertion description "[In patients with Dukes stage C/D colorectal cancer, the Cox Proportional Hazard Model analysis demonstrated a significant association between increased patient survival and low expression of ITGB2 (p = 0.011) and NPR1 (p = 0.023) genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107126.RAVFrdqy-3PyZZweV15u0rxhAX6EDOJ34QlUcxA9VV-Ao130_provenance.
- NP107133.RAczj5Xd_Zj_-phHVEoFyOPBYKOx7ylk_0dKX36rSzjdE130_assertion description "[glycogen synthase kinase 3beta protein is expressed in normal colon epithelium and aberrantly distributed in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107133.RAczj5Xd_Zj_-phHVEoFyOPBYKOx7ylk_0dKX36rSzjdE130_provenance.
- NP107134.RAQ5KJ5d6ptFOD4CgHu-oTOjFKATKTu-GZWFFjt_PaFNw130_assertion description "[A functional, cooperative relationship between endogenous N-RAS and gelsolin is identified in colorectal cancer cell lines that correlates with survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107134.RAQ5KJ5d6ptFOD4CgHu-oTOjFKATKTu-GZWFFjt_PaFNw130_provenance.
- NP107141.RAfnkXQSLbzAX-A04EHyQCajk40opgoEOyAGwt5ygQ6dk130_assertion description "[AP-2alpha binds directly to APC, stabilizes APC/beta-catenin interaction in the nucleus, attenuates beta-catenin/TCF4 interaction, and inhibits TOPflash reporter activity in human colorectal cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107141.RAfnkXQSLbzAX-A04EHyQCajk40opgoEOyAGwt5ygQ6dk130_provenance.
- NP107142.RAVYFKqu8agbJ-d2fC4KQ56HxiDr4uh49N08WkPk48F5U130_assertion description "[expression of SSAT mediated by Ad-SSAT infection inhibits the growth of colorectal cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107142.RAVYFKqu8agbJ-d2fC4KQ56HxiDr4uh49N08WkPk48F5U130_provenance.
- NP107144.RAXYZY0eptX--cfwExtxTIVHByCuSaDMBgB4LpEUpxY_s130_assertion description "[Increased expression of Reg genes, specifically Reg IV contribute to adenoma formation and lead to increased resistance to apoptotic cell death in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107144.RAXYZY0eptX--cfwExtxTIVHByCuSaDMBgB4LpEUpxY_s130_provenance.
- NP107147.RAbnGN3a38rE31ZpSuiXm7U2kt938X02uGd_UrsvsngXs130_assertion description "[XIAP expression in colorectal cancer is regulated by hepatocyte growth factor/C-met pathway via Akt signaling ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107147.RAbnGN3a38rE31ZpSuiXm7U2kt938X02uGd_UrsvsngXs130_provenance.
- NP107149.RARncyHhRYf2fmDKlXlYPy8lgLuYZj7E_zMffiNcl6RGU130_assertion description "[Upregulation of PGC-1alpha and PGC-1beta in the colorectal tumor cells can be part of an adaptation mechanism to help overcome the severe consequences of mtDNA mutations on oxidative phosphorylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107149.RARncyHhRYf2fmDKlXlYPy8lgLuYZj7E_zMffiNcl6RGU130_provenance.
- NP107153.RARffiMQ7Yz8eu_kIYQmjp0C07wKnlF-0swV2dF2178cs130_assertion description "[The expression of the alpha5 (IV)/alpha6 (IV) chains was down-regulated in colorectal cancer, and the loss of expression of the alpha5 (IV)/alpha6 (IV) chains was associated with the hypermethylation of their promoter region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107153.RARffiMQ7Yz8eu_kIYQmjp0C07wKnlF-0swV2dF2178cs130_provenance.
- NP107156.RAR9LozBCkuTbYm1lehFvx_Un6JykG42rETQcAZBQZ0Ko130_assertion description "[Intensive follow-up by serial assay of CEA and cytokeratins (8, 18, 19) allows early detection of colorectal neoplasm recurrence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107156.RAR9LozBCkuTbYm1lehFvx_Un6JykG42rETQcAZBQZ0Ko130_provenance.
- NP107161.RAc1-NyRoMIvlUGb6qbN1EuRvbSjpj7pyqrYnTMiqgwH8130_assertion description "[MYH11 mutations in patients with colorectal cancer, Peutz-Jeghers syndrome and juvenile polyposis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107161.RAc1-NyRoMIvlUGb6qbN1EuRvbSjpj7pyqrYnTMiqgwH8130_provenance.
- NP107162.RAZasbVxQc8mIWUAkqPHoGBI9Fntt250iLneCFJJu_eCk130_assertion description "[C/C genotype in exon 6 of uPA gene can be further considered as being related to colorectal cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107162.RAZasbVxQc8mIWUAkqPHoGBI9Fntt250iLneCFJJu_eCk130_provenance.
- NP107166.RAXrsP8jaOFv6BrSS-AyFPPsxFn_mwmI4iB3BPBU4fSnU130_assertion description "[The positive feedback loop between TOPK and ERK2 increases tumorigenesis properties of HCT116 colorectal cancer cells, and TOPK-regulated signaling may serve as a potential therapeutic target in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107166.RAXrsP8jaOFv6BrSS-AyFPPsxFn_mwmI4iB3BPBU4fSnU130_provenance.
- NP107178.RAfvhsXybjQgCAvnFltJ3maSHjHDEtl75wbutWIGlS11c130_assertion description "[the oncogenic role of KLK6 in colorectal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107178.RAfvhsXybjQgCAvnFltJ3maSHjHDEtl75wbutWIGlS11c130_provenance.
- NP107181.RAYpnTk-ewZ2obt1B6Ph1oRfvR2-iRneE2aHVne5yuqmE130_assertion description "[Csk suppression is an important early event in colorectal cancer pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP107181.RAYpnTk-ewZ2obt1B6Ph1oRfvR2-iRneE2aHVne5yuqmE130_provenance.