Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence GPVI+is+able+to+support+synergy+with+vWF. assertion.
- assertion asSentence GPVI+allele+is+an+independent+risk+factor+of+premature+myocardial+infarction. assertion.
- assertion asSentence Polymorphic+variation+at+the+GP6+locus+is+associated+with+risk+of+acute+myocardial+infarction+in+men+and+women. assertion.
- assertion asSentence Claudin+18+staining+can+aid+in+diagnosis+of+gastrointestinal+signet+ring+cell+carcinoma. assertion.
- assertion asSentence Increased+expression+of+claudin-18+is+associated+with+colitis. assertion.
- assertion asSentence High+claudin+18+is+associated+with+intraductal+papillary+mucinous+neoplasms+of+the+pancreas. assertion.
- assertion asSentence The+turnover+of+Paip2+in+the+cell+is+mediated+by+EDD+and+is+regulated+by+PABP. assertion.
- assertion asSentence All+investigated+mutant+proteins+display+impaired+catalytic+properties+and%2For+reduced+thermostability%2C+providing+a+rationale+for+the+pathological+effects+of+the+mutations. assertion.
- assertion asSentence RN181+suppresses+the+tumorigenesis+of+hepatocellular+carcinoma+through+the+inhibition+of+ERK%2FMAPK+signaling+in+the+liver. assertion.
- assertion asSentence Golgi+apparatus+in+prostate+cancer+cells+differs+from+the+normal+Golgi+by+elevated+levels+of+two+molecules%2C+GOLPH2+and+MYO6. assertion.
- assertion asSentence GP73+is+a+sensitive+and+specific+tumor+marker+for+diagnosing+hepatitis+B-related+hepatocellular+carcinoma+in+Asians. assertion.
- assertion asSentence Human+TLR7+or+TLR8+independently+confer+responsiveness+to+the+antiviral+compound+R-848. assertion.
- assertion asSentence A+profound+sex-dependent+pathway+of+TLR7-induced+interferon+%28IFN%29-alpha+production+is+revealed+with+higher+production+in+females. assertion.
- assertion asSentence TLR-7+signaling+stimulates+apoptosis+resistance%2C+associated+with+enhanced+iNOS+expression+%28protein+and+mRNA%29+and+NO+release%2C+notably+through+an+NF-kappaB-dependent+activation+of+the+NO+pathway. assertion.
- assertion asSentence The+ligand-induced+activation+of+TLR7+leads+to+the+accumulation+of+hypoxia-inducible+factor+1+alpha+%28HIF-1alpha%29+protein+in+THP-1+human+myeloid+macrophages+via+redox-+and+reactive+nitrogen+species-dependent+mechanisms. assertion.
- assertion asSentence Cultured+human+melanocytes+express+functional+toll-like+receptors+2-4%2C+7+and+9. assertion.
- assertion asSentence Activation+of+endosomal+TLRs+7%2C+8+and+4+leads+to+downregulation+of+degradative+HIF-1+alpha+prolyl+hydroxylation. assertion.
- assertion asSentence Triggering+of+TLR7+and+TLR8+expressed+by+human+lung+cancer+cells+induces+cell+survival+and+chemoresistance. assertion.
- assertion asSentence Cigarette+smoke+suppresses+key+plasmacytoid+dendritic+cells+functions+upon+viral+infection+by+a+mechanism+that+involves+downregulation+of+TLR7+expression+and+decreased+activation+of+IRF-7. assertion.
- assertion asSentence Toll-like+receptor+7+is+crucial+for+development+of+age-related+B+cell+population. assertion.
- assertion asSentence Dual+or+triple+activation+of+TLR7%2C+TLR8%2C+and%2For+TLR9+by+single-stranded+oligoribonucleotides. assertion.
- assertion asSentence TRIM59+interacts+with+ECSIT+as+an+adaptor+protein+required+for+the+TLR-mediated+transduction+pathway. assertion.
- assertion asSentence PLUNC+transgene+is+associated+with+enhanced+bacterial+killing+and+decreased+inflammation+after+exposure+with+a+major+human+airway+pathogen%2C+the+Gram-negative+bacterium+Pseudomonas+aeruginosa%2C+both+in+vitro+and+in+vivo. assertion.
- assertion asSentence Overexpression+of+KCNK9+in+cell+lines+promotes+tumor+formation+and+confers+resistance+to+both+hypoxia+and+serum+deprivation. assertion.
- assertion asSentence KCNK9+gene+is+imprinted+in+human+and+mouse%2C+exhibiting+preferential+expression+from+the+maternal+allele+in+brain. assertion.
- assertion asSentence Human+TLR7+or+TLR8+independently+confer+responsiveness+to+the+antiviral+compound+R-848. assertion.
- assertion asSentence Ciprofloxacin+inhibits+lipopolysaccharide-induced+toll-like+receptor-4+and+8+expression+on+human+monocytes+derived+from+adult+and+cord+blood. assertion.
- assertion asSentence Btk+as+a+key+signaling+molecule+that+interacts+with+and+acts+downstream+of+TLR8+and+TLR9. assertion.
- assertion asSentence DCIR+is+an+antigen+presenting+cell+receptor+that+is+endocytosed+efficiently+in+a+clathrin-dependent+manner+and+negatively+affects+TLR8-mediated+cytokine+production. assertion.
- assertion asSentence A+five-amino-acid+motif+in+the+undefined+region+of+the+TLR8+ectodomain+is+required+for+species-specific+ligand+recognition. assertion.
- assertion asSentence C%2FEBP%7Bdelta%7D+and+STAT-1+are+required+for+TLR8+transcriptional+activity. assertion.
- assertion asSentence HBV+X+gene+enhanced+SPG21+gene+promoter+activity%2C+SPG21+mRNA+expression+and+SPG21+protein+production+in+HepG2+cells+in+a+dose-dependent+manner. assertion.
- assertion asSentence FN14+is+the+sole+mediator+of+the+multiple+pathways+of+TWEAK-induced+cell+death+in+all+TWEAK-sensitive+tumor+cell+lines. assertion.
- assertion asSentence TWEAK+acts+on+human+keratinocytes+as+an+inducer+of+RANTES+via+Fn14. assertion.
- assertion asSentence Oligomerization+of+soluble+TWEAK+differentially+affects+Fn14-mediated+activation+of+the+classical+and+nonclassical+NF-kappa+B+pathway. assertion.
- assertion asSentence Regulation+of+TWEAKR+expression+by+Kaposi%27s+sarcoma-associated+herpesvirus+microRNA+prevents+TWEAK-induced+apoptosis+and+inflammatory+cytokine+expression. assertion.
- assertion asSentence TWEAK%2FFn14+signalling+is+important+in+the+pathogenesis+of+inflammation+and+bone+erosion+in+rheumatoid+arthritis. assertion.
- assertion asSentence Destruction-box+specificities+of+APC%2FC%28fzy%29+and+APC%2FC%28fzr%29%26+successive+activation+of+APC%2FC+by+fzy+%26+fzr+establish+the+temporal+substrate+degradation+pattern%2C+explaining+why+some+endogenous+RXXL+substrates+are+degraded+by+fzy+%26+others+by+fzr+complexes. assertion.
- assertion asSentence In+response+to+genotoxic+stress+in+G2%2C+the+phosphatase+Cdc14B+translocates+from+the+nucleolus+to+the+nucleoplasm+and+induces+the+activation+of+the+ubiquitin+ligase+APC%2FC%28Cdh1%29%2C+with+the+consequent+degradation+of+Plk1%2C+a+prominent+mitotic+kinase. assertion.
- assertion asSentence Anaphase-promoting+complex%2Fcyclosome-Cdh1+coordinates+glycolysis+and+glutaminolysis+with+transition+to+S+phase+in+human+T+lymphocytes. assertion.
- assertion asSentence BLU%2C+a+candidate+tumor+suppressor+gene%2C+located+at+the+commonly+deleted+region+3p21.3%2C+is+an+E2F-regulated%2C+stress-responsive+gene+and+inactivated+by+both+epigenetic+and+genetic+mechanisms+in+nasopharyngeal+carcinoma. assertion.
- assertion asSentence EDD+ubiquitinates+beta-catenin+through+Lys29-+or+Lys11-linked+ubiquitin+chains%2C+leading+to+enhanced+stability+of+beta-catenin. assertion.
- assertion asSentence Increased+p53+levels+upon+EDD+depletion+cause+a+G%281%29+arrest%2C+as+co-depletion+of+EDD+and+p53+completely+rescues+this+effect+on+cell+cycle+progression. assertion.
- assertion asSentence Both+TRPV1+and+TRPV2+are+found+in+human+peripheral+blood+lymphocytes. assertion.
- assertion asSentence Human+corneal+epithelial+cells+possess+thermosensitive+TRPV2+activity. assertion.
- assertion asSentence Cultivated+HCjE+cells+and+human+conjunctiva+express+TRPV2%2C+mRNA. assertion.
- assertion asSentence Preexcitation+associated+with+the+R302Q+mutation+in+PRKAG2+is+associated+with+Mahaim+fibers. assertion.
- assertion asSentence POLK+interacts+with+a+C-terminal+region+of+REV1. assertion.
- assertion asSentence POLK+does+not+colocalize+in+replication+foci+with+PCNA. assertion.
- assertion asSentence In+mammalian+cells%2C+both+polymerases+kappa+and+iota+are+necessary+for+the+error-free+bypass+of+N%282%29-CEdG+and+N%282%29-CMdG. assertion.
- assertion asSentence Encodes+homeobox+transcription+factors+that+are+expressed+during+vasculogenesis. assertion.
- assertion asSentence The+apoptotic+engulfment+protein+Ced-6+participates+in+clathrin-mediated+yolk+uptake+in+Drosophila+egg+chambers. assertion.
- assertion asSentence FAAP20+binding+stabilizes+Rev1+nuclear+foci+and+promotes+interaction+of+the+Fanconi+anemia+core+with+PCNA-Rev1+DNA+damage+bypass+complexes. assertion.
- assertion asSentence DCDC2+influences+both+reading+and+memory+impairments. assertion.
- assertion asSentence Comparison+of+the+promoter+region+of+the+human+and+murine+gene. assertion.
- assertion asSentence 17beta-hydroxysteroid+dehydrogenase+type+7%2817beta-HSD+type+7%29was+significantly+upregulated+in+ovarian+tissue+of+patients+with+ovarian+endometriosis. assertion.
- assertion asSentence Upregulated+in+at+least+50%25+of+multiple+myeloma+cases+tested. assertion.
- assertion asSentence CRL4%28Cdt2%29-dependent+destruction+of+Set8+in+S+phase+preserves+genome+stability+by+preventing+aberrant+chromatin+compaction+during+DNA+synthesis. assertion.
- assertion asSentence JAMP+is+an+important+component+for+coordinated+clearance+of+misfolded+proteins+from+the+endoplasmic+reticulum. assertion.
- assertion asSentence APC2+Cullin+protein+and+APC11+RING+protein+comprise+the+minimal+ubiquitin+ligase+module+of+the+anaphase-promoting+complex. assertion.
- assertion asSentence A+reaction+mechanism+whereby+the+Selenocysteine+over+Cysteine+specificity+is+achieved+using+a+combination+of+chemical+and+physico-mechanical+control+mechanisms. assertion.
- assertion asSentence SIRT7+is+a+positive+regulator+of+Pol+I+transcription+and+is+required+for+cell+viability+in+mammals. assertion.
- assertion asSentence The+activated+IL-23%2FIL-17+axis+is+important+for+the+inflammatory+immunity+in+systemic+lupus+erythematosus. assertion.
- assertion asSentence The+IL-23+induced+cytokines+allow+for+the+subsequent+production+of+IL-12+and+amplify+the+IFN-gamma+production+in+the+type-1+cytokine+pathway. assertion.
- assertion asSentence VEGF+stimulates+HDAC7+phosphorylation+and+cytoplasmic+accumulation+modulating+MT-MMP1%2FMMP10+expression+and+angiogenesis. assertion.
- assertion asSentence HDAC7+interacts+with+beta-catenin+keeping+endothelial+cells+in+a+low+proliferation+stage. assertion.
- assertion asSentence PhiC31+integrase+interacts+with+TTRAP+and+inhibits+the+NFkappaB+activation. assertion.
- assertion asSentence A+combination+of+restrictive+chromatin+structures+at+the+HIV+long+terminal+repeat+and+limiting+P-TEFb+levels+contribute+to+transcriptional+silencing+leading+to+latency+in+primary+CD4%28%2B%29+T+cells. assertion.
- assertion asSentence TIF1alpha+interacts+with+TIF1gamma+and+the+coiled-coil+region+of+TIF1gamma+is+necessary+for+this+interaction. assertion.
- assertion asSentence Hyperthermia+incurred+platelet+glycoprotein+Ibalpha+ectodomain+shedding. assertion.
- assertion asSentence Ars2+contributes+to+histone+mRNA+3%27+end+formation+and+expression+and+these+functional+properties+of+Ars2+are+negatively+regulated+by+interaction+with+7SK+RNA. assertion.
- assertion asSentence Mammalian+and+yeast+U3+snoRNPs+are+matured+in+specific+and+related+nuclear+compartments. assertion.
- assertion asSentence V1H+can+function+as+an+adaptor+for+interactions+between+Nef+and+AP-2. assertion.
- assertion asSentence Feedback+mechanism+for+the+transcriptional+control+of+the+KLF13+gene+in+the+erythroid+environment. assertion.
- assertion asSentence Coexpression+of+PRP4+and+KLF13+increases+nuclear+localization+of+KLF13+and+CCL5+transcription. assertion.
- assertion asSentence The+CCZ1+gene+is+a+member+of+the+class+B+VPS+%28vacuolar+protein+sorting%29+genes+and+it+is+engaged+in+the+last+stage+of+delivery+of+multiple+kinds+of+cargo+to+the+yeast+vacuole. assertion.
- assertion asSentence ESCRT+subunit+is+important+for+degradation+of+the+epidermal+growth+factor+receptor+%28EGFR%29+and+for+transport+of+the+receptor+from+endosomes+to+lysosomes. assertion.
- assertion asSentence The+inherited+blindness+associated+protein+AIPL1+interacts+with+the+cell+cycle+regulator+protein+NUB1+in+the+retina. assertion.
- assertion asSentence Hsp16.2+expression+is+directly+correlated+with+the+histological+grade+of+brain+tumors. assertion.
- assertion asSentence Suppressor+of+Fused+represses+Gli-mediated+transcription+by+recruiting+the+SAP18-mSin3+corepressor+complex. assertion.
- assertion asSentence Shh+signaling+regulates+Sufu+activity+by+inducing+its+turnover+via+the+ubiquitin-proteasome+system. assertion.
- assertion asSentence Ornithine+decarboxylase+antizyme+Oaz3+modulates+protein+phosphatase+activity. assertion.
- assertion asSentence The+tumor+suppressor+Cdc73+functionally+associates+with+CPSF+and+CstF+3%27+mRNA+processing+factors. assertion.
- assertion asSentence Membrane+recruitment+of+the+cargo-selective+retromer+subcomplex+VPS35%2F29%2F26+is+catalysed+by+the+small+GTPase+Rab7+and+inhibited+by+the+Rab-GAP+TBC1D5. assertion.
- assertion asSentence PAD3+is+co-located+with+filaggrin+within+the+filamentous+matrix+of+the+deeper+corneocytes+where+the+protein+is+deiminated. assertion.
- assertion asSentence Hyperghrelinemia+in+Prader-Willi+syndrome+and+pituitary+stalk+interruption+not+related+to+growth+hormone+secretion. assertion.
- assertion asSentence Lower+cord+ghrelin+levels+are+associated+with+slower+weight+gain+from+birth+to+3+months+of+age. assertion.
- assertion asSentence Specific+haplotypes+of+the+ghrelin+ligand+and+its+receptor+act+epistatically+to+affect+susceptibility+or+tolerance+to+myocardial+infarction+and%2For+corony+heart+disease. assertion.
- assertion asSentence In+liver+cirrhosis%2C+altered+postprandial+glucose+and+ghrelin+are+associated+with+reduced+energy+intake+and+weight+loss. assertion.
- assertion asSentence Association+with+ghrelin+levels+and+iron+deficiency+and+to+see+whether+changes+seen+in+iron+deficiency+%28ID%29+are+explained+by+ghrelin+levels. assertion.
- assertion asSentence Low+levels+of+ghrelin+in+fibromyalgia+are+not+related+to+the+changes+in+hypothalamo-pituitary-IGF-1+axis. assertion.
- assertion asSentence Ghrelin+concentrations+are+a+function+of+body+mass+indes+rather+than+feeding+status+in+obese+girls. assertion.
- assertion asSentence The+dysregulation+of+reactivity+of+T+cells+induced+by+ghrelin+is+associated+with+the+pathogenesis+of+Crohn%27s+disease. assertion.
- assertion asSentence Variants+of+the+ghrelin+and+GHSR+genes+are+not+major+contributors+to+height+variation+in+a+French+population. assertion.
- assertion asSentence Ghrelin+suppresses+the+secretion+of+FSH+in+humans. assertion.
- assertion asSentence Ghrelin+plays+a+significant+autocrine+and+paracrine+role+in+the+maintenance+of+relaxation+in+the+myometrium+during+pregnancy. assertion.
- assertion asSentence Ghrelin+and+neurotensin+expression+systems+are+markedly+altered+in+the+brain+of+Alzheimer%27s+disease+patients. assertion.
- assertion asSentence Ghrelin+is+an+essential+factor+in+monocyte+functional+activity+regulation+during+pregnancy. assertion.
- assertion asSentence Ghrelin+immunopositivity+does+not+serve+as+a+biomarker+of+biologic+behavior%2C+prognosis+and+therapeutic+responsiveness+in+pituitary+adenomas. assertion.
- assertion asSentence Loss+of+ghrelin+is+associated+with+recurrence+in+invasive+breast+cancer. assertion.