Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence A+discrete+C-terminal+Ubc7p+binding+region+of+Cue1p+is+required+for+ER-associated+degradation+and+for+Ubc7p-dependent+ubiquitylation+by+Hrd1p+in+vitro. assertion.
- assertion asSentence yKu+and+core+X+play+a+pivotal+role+in+maintaining+genome+stability+through+nuclear+architecture+by+mediating+a+defensive+fold-back+structure+at+yeast+chromosome+ends. assertion.
- assertion asSentence Set1+promotes+proper+early+termination+by+the+Nrd1-Nab3-Sen1+complex+by+affecting+the+kinetics+of+Pol+II+transcription+in+early+elongation. assertion.
- assertion asSentence eIF1+and+eIF1A+promote+an+open%2C+scanning-competent+preinitiation+complex+that+closes+upon+start+codon+recognition+and+eIF1+release+to+stabilize+ternary+complex+binding+and+clamp+down+on+mRNA. assertion.
- assertion asSentence Rap1%2FGcr1%2FGcr2+transcriptional+activation+in+yeast+cells+occurs+through+a+large+anchored+protein+platform%2C+the+Nup84+nuclear+pore+subcomplex. assertion.
- assertion asSentence The+Tom70+monomer+is+the+functional+unit+mediating+initial+chaperone+docking+and+precursor+recognition. assertion.
- assertion asSentence Increasing+heat-shock+protein+40+chaperone+Sis1+activity+before+Rnq1-GFP+expression%2C+shifted+Rnq1-GFP+aggregation+from+the+cytosol+to+the+nucleus. assertion.
- assertion asSentence Gyp5p+and+Gyl1p+are+involved+in+control+of+polarized+exocytosis. assertion.
- assertion asSentence The+function+of+the+Tlc1+terminator+region+depends+on+the+Nrd1%2FNab3+transcription+termination+pathway. assertion.
- assertion asSentence Genotoxic+stress+during+S+phase+specifically+induces+MBF-regulated+genes+via+direct+phosphorylation+of+Nrm1+by+Rad53%2C+the+effector+checkpoint+kinase. assertion.
- assertion asSentence Rap1%2FGcr1%2FGcr2+transcriptional+activation+in+yeast+cells+occurs+through+a+large+anchored+protein+platform%2C+the+Nup84+nuclear+pore+subcomplex. assertion.
- assertion asSentence A+tps1+mutant+defective+in+the+TPS+catalytic+subunit+cultivated+on+trehalose%2C+or+on+a+dual+source+of+carbon+made+of+galactose+and+trehalose%2C+accumulated+high+levels+of+intracellular+trehalose+by+its+Agt1p-mediated+transport. assertion.
- assertion asSentence The+interaction+between+eIF5+and+eIF1A+is+involved+in+maintaining+the+fidelity+of+start+codon+AUG+recognition+in+vivo. assertion.
- assertion asSentence A+complex+of+the+GINS+and+Ctf4+components+of+the+replisome+progression+complex+is+crucial+to+couple+MCM2-7+to+DNA+polymerase+alpha. assertion.
- assertion asSentence Ctf4p+facilitates+Mcm10p+to+promote+the+DNA+replication. assertion.
- assertion asSentence Bur1+phosphorylates+the+Spt5+C-terminal+repeat+domain+%28CTD%29+both+in+vivo+and+in+isolated+elongation+complexes+in+vitro. assertion.
- assertion asSentence Misincorporation+of+iron+into+yeast+Sod2p+does+not+correlate+with+significant+changes+in+the+average+oxidation+state+or+coordination+chemistry+of+bulk+mitochondrial+iron. assertion.
- assertion asSentence Tec1+is+able+to+regulate+TCS-mediated+gene+expression+by+Ste12-dependent+and+Ste12-independent+mechanisms+that+enable+promoter-specific+transcriptional+control. assertion.
- assertion asSentence Set1+promotes+proper+early+termination+by+the+Nrd1-Nab3-Sen1+complex+by+affecting+the+kinetics+of+Pol+II+transcription+in+early+elongation. assertion.
- assertion asSentence The+yeast+INSIG+homologs+NSG1+and+NSG2+function+to+control+the+stability+of+yeast+Hmg2p%2C+the+HMGR+isozyme+that+undergoes+regulated+ubiquitination. assertion.
- assertion asSentence Rpn10%2FRpn11+interaction+couples+proteasome+assembly+to+substrate+binding. assertion.
- assertion asSentence That+ISC1+controls+cell+morphology+in+combination+with+checkpoint+regulators+Swe1%2C+Cdk1%28CDC28%29%2C+MRC1%2C+TOF1%2C+CSM3%2C+RAD9+and+Rad53. assertion.
- assertion asSentence The+gpp1gpp2+strain+is+hypersensitive+to+cell+wall+stress+such+as+treatment+with+beta-1%2C3-glucanase+containing+cocktail+Zymolyase+and+chitin-binding+dye+Calcofluor-white. assertion.
- assertion asSentence Casein+kinase+1-dependent+phosphorylation+and+HECT-ubiquitin+ligase+Rsp5-dependent+ubiquitylation+are+required+for+Jen1+endocytosis. assertion.
- assertion asSentence The+Reg1-Glc7+protein+phosphatase+1+and+Sit4+type+2A-like+phosphatase+are+largely+responsible+for+dephosphorylation+of+Thr-210+of+Snf1%281-309%29. assertion.
- assertion asSentence Rad23+and+Ddi1+interact+with+each+other+by+using+UBL%2FUBA+domain+interactions+in+a+manner+that+does+not+preclude+their+interaction+with+ubiquitin. assertion.
- assertion asSentence Ubp3+deubiquitylates+RNA+polymerase+II+in+yeast. assertion.
- assertion asSentence Oms1p+is+a+mitochondrial+inner+membrane+protein+inserted+independently+of+Oxa1p. assertion.
- assertion asSentence The+Sus1-binding+site+on+Sgf11+is+somewhat+shorter+than+on+Sac3+and+is+based+on+a+narrower+hydrophobic+stripe. assertion.
- assertion asSentence The+function+of+the+Tlc1+terminator+region+depends+on+the+Nrd1%2FNab3+transcription+termination+pathway. assertion.
- assertion asSentence Lnp1p+and+Sey1p+act+antagonistically+to+balance+endoplasmic+reticular+polygonal+network+formation. assertion.
- assertion asSentence Termination+of+the+transcriptional+activity+of+ComX+is+not+dependent+on+proteolysis+of+ComW. assertion.
- assertion asSentence SidA+inhibits+division+by+binding+directly+to+FtsW+to+prevent+the+final+constriction+of+the+cytokinetic+ring. assertion.
- assertion asSentence Flavocytochrome+c+is+involved+in+the+sulfide+oxidation+in+vivo. assertion.
- assertion asSentence DsbA+catalyzes+the+formation+of+a+disulfide+bond+in+the+D3+lectin-like+domain+of+intimin+in+the+periplasm. assertion.
- assertion asSentence Despite+lacking+the+ubiquitin-interaction+motif%2C+Trypanosoma+epsin+maintains+a+similar+role+to+metazoan+epsin+in+endocytosis+and+participates+as+a+clathrin-associated+adaptor. assertion.
- assertion asSentence Chaperoning+of+the+alpha-domain+of+IcsA+during+transit+through+the+periplasm+relies+on+the+critical+role+played+by+Skp. assertion.
- assertion asSentence MxiG+is+involved+in+type+III+secretion+system+regulation. assertion.
- assertion asSentence The+pph3+mutant+under+starvation+conditions+formed+immature+fruiting+bodies+and+reduced+sporulation. assertion.
- assertion asSentence B.+hermsii+ResT+exhibits+a+more+restricted+substrate+usage+pattern+than+B.+burgdorferi+ResT+and+cannot+efficiently+resolve+a+Type+2+telomere. assertion.
- assertion asSentence The+LIC10365+activated+endothelium+in+such+a+manner+that+E-selectin+and+intercellular+adhesion+molecule+1+%28ICAM-1%29+became+upregulated+in+a+dose-dependent+fashion. assertion.
- assertion asSentence Interaction+of+HSP60+with+TLR+%28toll-like+receptors%29in+gastric+epithelial+cells+contributes+to+development+of+gastic+inflammation+of+H.+pylori+infection. assertion.
- assertion asSentence Inhibition+of+focal+adhesion+kinase+by+SHP-2+plays+a+crucial+role+in+the+morphogenetic+activity+of+Helicobacter+pylori+CagA. assertion.
- assertion asSentence Diverse+CagA+and+vacA+genes+are+correlated+with+atrophic+gastritis+and+gastric+cancer+in+Helicobacter+infections+in+Costa+Rica. assertion.
- assertion asSentence FldA+induction+is+independent+of+the+Fur+protein+under+iron+starvation. assertion.
- assertion asSentence Functioning+of+the+fur+Gene+is+Required+for+the+acid+tolerance+response. assertion.
- assertion asSentence The+crystal+structure+of+a+complex+between+the+isolated+domain+I+of+L1+from+the+bacterium+Thermus+thermophilus+and+a+specific+mRNA+fragment+from+Methanoccocus+vannielii. assertion.
- assertion asSentence The+specific+blocking+of+PA-IIL%2C+a+fucose-binding+lectin+of+the+human+pathogen+P.+aeruginosa%2C+by+milk+oligosaccharides%2C+is+demonstrated. assertion.
- assertion asSentence AlgL+is+bifunctional+with+a+structural+role+in+the+scaffold+and+a+role+in+degrading+free+alginate+polymers+in+the+periplasm+%28AlgL%29. assertion.
- assertion asSentence The+expression+of+ExoS+in+HeLa+cells+by+eukaryotic+expression+vector+effectively+caused+apoptosis+in+an+ADP-ribosylation+%28ADPRT%29+activity-dependent+manner. assertion.
- assertion asSentence RhlA+is+necessary+and+sufficient+to+form+the+acyl+moiety+of+rhamnolipid. assertion.
- assertion asSentence An+intact+inner+membrane+complex+is+required+for+optimal+formation+of+the+outer+membrane+complex+of+the+type+IVa+pilus+system+in+P.+aeruginosa. assertion.
- assertion asSentence Vfr+has+a+significant+higher+affinity+for+both+cAMP+and+cGMP. assertion.
- assertion asSentence Fumarase+C+%28FUM+C%29+and+H2O-forming+NADH+oxidase+%28NOX%29+play+a+pivotal+role+in+the+adaptation+of+Pseudomonas+fluorescens+to+the+toxicity+of+Al+and+Ga. assertion.
- assertion asSentence KGDH+and+GDH+work+in+tandem+to+modulate+alpha-ketoglutarate+homeostasis. assertion.
- assertion asSentence ColRS+signal+system+and+TtgABC+efflux+pump+are+involved+in+the+phenol+tolerance+of+P.+putida. assertion.
- assertion asSentence The+main+underlying+regulatory+mechanisms+of+the+tod+structural+genes+are+at+the+levels+of+catabolite+repression+control+from+P%28todS%29+and+transcription+activation%2C+mediated+by+the+TodT+response+regulator+through+a+regulatory+cascade. assertion.
- assertion asSentence Neither+mutation+of+gcl%2C+glcB%2C+aceA+nor+any+of+the+respective+double+mutation+influenced+glyoxylic+acid+conversion. assertion.
- assertion asSentence PpAroA1+from+Pseudomonas+putida+can+efficiently+confer+tobacco+plants+with+high+glyphosate+tolerance. assertion.
- assertion asSentence LrpE+is+associated+with+negatively+regulating+the+production+of+Hrp+pili+on+the+cell+surface+of+R.+solanacearum+to+disperse+bacterial+cells+from+aggregates. assertion.
- assertion asSentence Another+remarkable+feature+is+the+occurrence+of+a+C-terminal+leucine+residue+instead+of+the+canonical+phenylalanine+or+tryptophan+residue. assertion.
- assertion asSentence Actin+dynamics+play+a+role+in+the+activation+of+gene-for-gene+resistance+in+Arabidopsis+thaliana+following+inoculation+with+the+phytopathogenic+bacterium+Pseudomonas+syringae+pv+tomato. assertion.
- assertion asSentence XopJ+has+a+role+in+the+inhibition+of+cell+wall-based+defense+responses. assertion.
- assertion asSentence XcBCP+carries+out+its+oxidoreduction+activity+through+the+alternate+opening+and+closing+of+the+substrate+entry+channel+and+the+disulfide-bond+pocket. assertion.
- assertion asSentence EglXoB+endoglucanase+is+required+for+pathogenesis+of+rice+bacterial+blight+disease. assertion.
- assertion asSentence RpoS+and+PsrA+are+involved+in+regulation+of+encystment+and+alkylresorcinol+synthesis+in+A.+vinelandii. assertion.
- assertion asSentence Hydantoinase+%28hyuH%29+and+N-carbamoylase+%28hyuC%29+activities+are+regulated+by+growth+phase+of+the+cell%2C+the+presence+or+absence+of+hydantoin+and+nitrogen+catabolite+repression. assertion.
- assertion asSentence Purified+RepC+bound+to+a+site+within+repC+with+moderate+affinity%2C+high+specificity+and+with+twofold+cooperativity. assertion.
- assertion asSentence D-tartrate+dehydratase-catalyzed+reaction+is+a+%22simple%22+extension+of+the+two-step+reaction+catalyzed+by+mandelate+racemase+base-catalyzed+proton+abstraction+to+generate+a+Magnesium-stabilized+enediolate+intermediate. assertion.
- assertion asSentence An+ABC+transporter+plays+a+role+in+potassium+transport+regulation+and+alkaline+stress. assertion.
- assertion asSentence The+crystal+structure+of+ChoX+in+an+unusual%2C+ligand-free+conformation+that+represents+a+semi-closed+form+of+ChoX. assertion.
- assertion asSentence RhaU+of+Rhizobium+leguminosarum+is+a+rhamnose+mutarotase. assertion.
- assertion asSentence RapA1+protein+functions+are+related+to+early+legumes+root+adsorption+and+rhizosphere+colonization. assertion.
- assertion asSentence The+flaA+gene+of+Legionella+pneumophila+has+highly+expressed+in+prokaryotic+cell. assertion.
- assertion asSentence Laz+mutant+Neisseria+meningitidis+strains+are+hypersensitive+to+hydrogen+peroxide+and+copper+%28laz%29. assertion.
- assertion asSentence Mutation+of+GapA-1+significantly+affects+bacterial+adhesion+to+human+epithelial+and+endothelial+cells. assertion.
- assertion asSentence The+NMR+structure+of+NP_888769.1+includes+seven+beta-strands+and+two+alpha-helices. assertion.
- assertion asSentence The+cytotoxic+effector+BteA+protein+is+expressed+at+higher+levels+in+B.+pertussis+nonvaccine-type+strains+than+in+vaccine-type+strains. assertion.
- assertion asSentence Residues+375-485+within+CyaA+assists+membrane+insertion+and+translocation+of+CyaA+toxin+across+the+plasma+membrane+of+target+cells. assertion.
- assertion asSentence Expression+of+the+megL+gene+in+the+C.+freundii+genome+occurs+only+upon+induction+by+a+significant+amount+of+L-methionine. assertion.
- assertion asSentence Replacement+of+Asp214+in+tyrosine+phenol-lyase+%28TPL%29+with+Ala+and+Asn+leads+to+alteration+of+active+site+conformations+and+to+a+decrease+in+the+cofactor+affinity+of+about+four+orders+of+magnitude. assertion.
- assertion asSentence OMPE36+played+an+important+role+in+carbapenem+resistance+in+vivo+and+in+vitro. assertion.
- assertion asSentence Increased+folding+stability+of+TEM-1+beta-lactamase+by+in+vitro+selection. assertion.
- assertion asSentence The+toxicity+of+EHEC-Hly+to+microvascular+endothelial+cells+plausibly+contributes+to+the+virulence+of+the+stx-negative+E.+coli+O26+strains+and+to+the+pathogenesis+of+HUS. assertion.
- assertion asSentence YidC+functions+as+a+membrane-based+chaperone+%27module%27+to+facilitate+assembly+of+a+subset+of+protein+complexes+in+the+inner+membrane+of+E.+coli. assertion.
- assertion asSentence Pre-tRNA+binding+affinities+for+Bacillus+subtilis+and+Escherichia+coli+RNase+P+are+enhanced+by+sequence-specific+contacts+between+the+fourth+pre-tRNA+nucleotide+on+the+5%27+side+of+the+cleavage+site+and+the+RNase+P+protein+subunit. assertion.
- assertion asSentence Gamma-Glutamylcysteine+synthetase+from+Escherichia+coli+has+the+ability+to+combine+Glu+and+amines+to+form+gamma-glutamylamides. assertion.
- assertion asSentence The+formation+of+a+complex+between+the+denatured+monomeric+form+of+Phb+and+the+dissociated+forms+of+GroEL+is+detected+during+heating+at+46+degrees+C. assertion.
- assertion asSentence Lysine+161+is+not+absolutely+essential+for+catalysis. assertion.
- assertion asSentence Parvulin+10+%28Par10%29%2C+an+abundant+Escherichia+coli+peptidyl+prolyl+cis%2Ftrans+isomerase%2C+physically+interacts+with+the+alkyl+hydroperoxide+reductase+subunit+C+%28AhpC%29+in+bacterial+cell+extracts. assertion.
- assertion asSentence In+the+rate-limiting+intermediate+of+a+chaperonin-assisted+protein+folding+reaction%2C+the+unfolded+polypeptide+in+the+cage+partly+protrudes+through+a+narrow+space+near+the+GroEL%2FGroES+interface. assertion.
- assertion asSentence An+insertional+mutation+into+the+Ler+linker+region+diminished+oligomerization+activity. assertion.
- assertion asSentence Cooperativity+of+cAMP+binding+is+generally+correlated+to+the+global+dynamics+of+the+protein+and+DNA+binding+affinity. assertion.
- assertion asSentence Transcription+factor+NusA+modulates+the+transcriptional+pausing+of+RNA+polymerase+in+Escherichia+coli. assertion.
- assertion asSentence The+Arg266+residue+of+the+Escherichia+coli+glutamyl-tRNA+synthetase+is+essential+for+efficient+glutamylation+of+tRNA. assertion.
- assertion asSentence Alpha-hemolysin+encoding+gene+can+be+found+on+the+chromosome+and+plasmid+in+Escherichia+coli+strains. assertion.
- assertion asSentence The+transposase+permits+tight+control+of+IS+proliferation+providing+a+mechanistic+explanation+for+cis+regulation+of+transposition+involving+an+unexpected+partner%2C+the+ribosome. assertion.
- assertion asSentence For+Esigma54+promoters%2C+loading+of+template+DNA+within+the+catalytic+cleft+of+RNA+polymerase+is+dependent+on+fast+ATP+hydrolysis+steps+that+trigger+changes+in+the+beta%27+jaw+domain. assertion.
- assertion asSentence HSP60+from+Klebsiella+pneumoniae+protects+mononuclear+cells+from+apoptotic+cell+death+induced+by+dexamethasone. assertion.
- assertion asSentence 17+of+18+MBL-producing+isolates+carried+blaVIM-1. assertion.