Nanopublications LDF server

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

• NP118591.RAY_eCb8KPLFE4G_YJZ0_eOgKN8cPM0qhLQOBIhShMcrA130_assertion description "[Noninvasive dynamic fluorescence imaging of human melanomas reveals that targeted inhibition of bFGF or FGFR-1 in melanoma cells blocks tumor growth by apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118591.RAY_eCb8KPLFE4G_YJZ0_eOgKN8cPM0qhLQOBIhShMcrA130_provenance.
• NP118601.RAXxEnCOp0LpIsoHhTLavVMjmQ1Ib6BJh5RfXoG9Fl4N8130_assertion description "[KIR2DS4 interacts with a non-class-I MHC protein on melanomas/interaction is both specific & functional/mutagenesis shows that the AAs involved in recognizing this novel ligand are different from those interacting with HLA-Cw4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118601.RAXxEnCOp0LpIsoHhTLavVMjmQ1Ib6BJh5RfXoG9Fl4N8130_provenance.
• NP118606.RAZNkMIYM-Fpg2JEULdTAjXkr1LIAZ3j2-ZuZD6Lwg2XU130_assertion description "[Expression of basic fibroblast growth factor (bFGF) was significantly associated with increased microvessel density in cutaneous melanomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118606.RAZNkMIYM-Fpg2JEULdTAjXkr1LIAZ3j2-ZuZD6Lwg2XU130_provenance.
• NP118607.RAZ3a3p3-mQ6XZP8AS-iJcB1CoZDtTv3dfQk8QkEYh024130_assertion description "[Overexpression of the 18 kDa basic fibroblast growth factor protein can promote autocrine melanoma cell growth and paracrine-driven angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118607.RAZ3a3p3-mQ6XZP8AS-iJcB1CoZDtTv3dfQk8QkEYh024130_provenance.
• NP118612.RARe0oTJ66Acbusxw6hR55Am-Jkm_ahimaJ_nuIh8xmC4130_assertion description "[The transformation of melanocytes to melanoma cells is characterised by abnormal proliferation due to cell cycle alterations/occurs through alterations in the retinoblastoma (Rb) and p53 tumour suppressor pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118612.RARe0oTJ66Acbusxw6hR55Am-Jkm_ahimaJ_nuIh8xmC4130_provenance.
• NP118614.RAXDa86S2ZQ-ZPphiYYkWBzJoK7qciRVHX70eHXIkIee8130_assertion description "[Data show that an increase in melanoma cell invasiveness requires not only expression but also phosphorylation of L-plastin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118614.RAXDa86S2ZQ-ZPphiYYkWBzJoK7qciRVHX70eHXIkIee8130_provenance.
• NP118617.RAU7JXi2xxTattEIX4cp5dweA4qLTPLn6bxufTDYdSXSE130_assertion description "[PAR-1 can be used with Breslow thickness and ulceration as a prognostic indicator for melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118617.RAU7JXi2xxTattEIX4cp5dweA4qLTPLn6bxufTDYdSXSE130_provenance.
• NP118620.RAe0dxvlVPXxwpTWGKrQKr0XhTKurbsbEgFpJ7L7rP6do130_assertion description "[The expression of OX40 on CD4+ T cells in sentinel lymph nodes draining primary melanomas decreased withe more advanced tumor features, suggesting an immunosuppressive effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118620.RAe0dxvlVPXxwpTWGKrQKr0XhTKurbsbEgFpJ7L7rP6do130_provenance.
• NP118622.RARYjrC0FzQzh_XxWLaUnVJlkM537Qfo7AJv3ZsdpAzmo130_assertion description "[Apaf-1 expression in 15 melanoma cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118622.RARYjrC0FzQzh_XxWLaUnVJlkM537Qfo7AJv3ZsdpAzmo130_provenance.
• NP118623.RARQdfGGFRNtUdln_Xi7stllNEjKfiZPJJC9FkRYNWUL0130_assertion description "[Loss of APAF-1 expression can be considered an indicator of malignant transformation in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118623.RARQdfGGFRNtUdln_Xi7stllNEjKfiZPJJC9FkRYNWUL0130_provenance.
• NP118624.RAV5s4jpMVOr8cg_GWjncICT9W3gWkDoA6tVRYQGQLPVE130_assertion description "[there is an inverse correlation between Apaf-1 expression and pathologic stage of melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118624.RAV5s4jpMVOr8cg_GWjncICT9W3gWkDoA6tVRYQGQLPVE130_provenance.
• NP118631.RAQpqkTkbZGAFzjzYdQIpsfssVlrBcJVnCni0juyAZ_l4130_assertion description "[Nuclear presence of survivin may be an independent biomarker for disease recurrence and overall survival in patients with Stage I and II melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118631.RAQpqkTkbZGAFzjzYdQIpsfssVlrBcJVnCni0juyAZ_l4130_provenance.
• NP118632.RAWZ7x9c-47LNky9rWk1xzZEGRmCLFC07ia8vnpPTxSaY130_assertion description "[Minor structural changes in a mutated human melanoma antigen (TPI) correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118632.RAWZ7x9c-47LNky9rWk1xzZEGRmCLFC07ia8vnpPTxSaY130_provenance.
• NP118636.RAcGGcD66Kg-5VNWPOfUZdHWeAH7I-zZV52Sga2vpCoqc130_assertion description "[Modification of local protooncogene Ets-1 level is likely being involved in the regulation of melanoma growth ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118636.RAcGGcD66Kg-5VNWPOfUZdHWeAH7I-zZV52Sga2vpCoqc130_provenance.
• NP118645.RAeptvRO5bHlcocA8LrrYb7sChQQFmjmges4dwdsZ4Pos130_assertion description "[The coexpression of heparanase and vascular endothelial growth factor in atypical melanocytes and melanoma cells suggests their function in cell migration and invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118645.RAeptvRO5bHlcocA8LrrYb7sChQQFmjmges4dwdsZ4Pos130_provenance.
• NP118646.RAfhzNNTBN50WFXXn-erhmUWU0ydsnItFLZlDXX-snipE130_assertion description "[one of the roles CREB plays in the acquisition of melanoma cells metastatic phenotype is affecting HPSE-1 activity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118646.RAfhzNNTBN50WFXXn-erhmUWU0ydsnItFLZlDXX-snipE130_provenance.
• NP118651.RARqq1Kc5xq6eCYTglf8yg64Aup5wvuzY3w3E2i6NbZy8130_assertion description "[constitutively activated in choroidal melanoma cell lines, independent of Ras, and regulated by B-RafV599E ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118651.RARqq1Kc5xq6eCYTglf8yg64Aup5wvuzY3w3E2i6NbZy8130_provenance.
• NP118658.RAaFThm8vBkJN8K3-k6_e1-TObwaCcyNvYBAlIp70wrCY130_assertion description "[Mutations in FGFR3 in melanoma by inhibition of nonsense-mediated mRNA decay.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118658.RAaFThm8vBkJN8K3-k6_e1-TObwaCcyNvYBAlIp70wrCY130_provenance.
• NP118659.RAXT5d6dkO3HPs_JBq7L6qtblSsKESqW5cZWt175HuOK8130_assertion description "[REVIEW: Nodal (and its signaling partners) present unique targets for both immunologic and pharmacologic therapies in metastatic melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118659.RAXT5d6dkO3HPs_JBq7L6qtblSsKESqW5cZWt175HuOK8130_provenance.
• NP118660.RATKzY1bpymeLMzDux_ivQUqwWtCv8IS-BBxsbkN0vIwY130_assertion description "[Identification of ARHGEF17, mutations in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118660.RATKzY1bpymeLMzDux_ivQUqwWtCv8IS-BBxsbkN0vIwY130_provenance.
• NP118663.RAZ7EQNRbQ-6mpxHyQhV-__vUITHd0LWsL5NW4rQvWPcY130_assertion description "[cFLIP represents an attractive therapeutic target for melanoma treatment, especially in combination with TRAIL receptor agonists.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118663.RAZ7EQNRbQ-6mpxHyQhV-__vUITHd0LWsL5NW4rQvWPcY130_provenance.
• NP118664.RAQCi8d4q2s14vsRS1mUh7r8ctpSR6o75amLJrn6Zccss130_assertion description "[the constitutively activated melanoma MAPK pathway stimulates activation of NF-kappaB hetero- and homodimers, which, in turn, drive iNOS expression and support melanoma tumorigenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118664.RAQCi8d4q2s14vsRS1mUh7r8ctpSR6o75amLJrn6Zccss130_provenance.
• NP118666.RARXFq7cAKqFtHegPYMucrR-qhichh10nstezXugcZ5uk130_assertion description "[study demonstrate that expression of the MDA-7 tumor suppressor can negatively regulate iNOS expression in malignant melanoma cell lines ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118666.RARXFq7cAKqFtHegPYMucrR-qhichh10nstezXugcZ5uk130_provenance.
• NP118667.RAa8ClwOFvLVTXZkUjKrc1EJY9aKk7AgYwvf-sI7Vc0FI130_assertion description "[In a prospective study we have also analyzed AMF receptor protein expression in primary tumors of 54 skin melanoma patients using IHC ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118667.RAa8ClwOFvLVTXZkUjKrc1EJY9aKk7AgYwvf-sI7Vc0FI130_provenance.
• NP118674.RAbRxwWB2FvMjEaXYVmLOislfXzZOv443_io153blJPJY130_assertion description "[TIMP-3 promotes apoptosis in melanoma cells through stabilization of three distinct death receptors and activation of their apoptotic signaling cascade through caspase-8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118674.RAbRxwWB2FvMjEaXYVmLOislfXzZOv443_io153blJPJY130_provenance.
• NP118677.RAZeGE7IxVqhYpGQRH0fWEs7wIMNd6tQLfxgZY2dAhHko130_assertion description "[human malignant melanoma cells express the inhibitory low-affinity Fc (gamma) receptor Fc (gamma) RIIB1 in 40% of tested metastases ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118677.RAZeGE7IxVqhYpGQRH0fWEs7wIMNd6tQLfxgZY2dAhHko130_provenance.
• NP118679.RAUEvz9x78IF3Ni2_b1DjbCTHnCWbaX1vqoMnpVqRkepE130_assertion description "[MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency/MELOE-1]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118679.RAUEvz9x78IF3Ni2_b1DjbCTHnCWbaX1vqoMnpVqRkepE130_provenance.
• NP118684.RAXh3W4oVr2lZFBwNaWEbB5cudhZs2qzwZDFDtnNJ5Lpw130_assertion description "[demonstrated a statistically significant decrease of the eIF3f gene copy number in melanoma compared with normal tissues with a tumor/normal ratio of 0.52 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118684.RAXh3W4oVr2lZFBwNaWEbB5cudhZs2qzwZDFDtnNJ5Lpw130_provenance.
• NP118685.RAeGmailOfeMXV9soYvf9-3bpLA0kL3ebQ-N6wYsDEmrg130_assertion description "[MUM1 appears to be a sensitive and specific immunohistochemical stain for melanocytic lesions and may prove to be a useful addition to the current panel of melanoma markers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118685.RAeGmailOfeMXV9soYvf9-3bpLA0kL3ebQ-N6wYsDEmrg130_provenance.
• NP118688.RAd09HyhOSIeAF8hzYqtbmY45-7-50NKf5yYVE6GPctoA130_assertion description "[Endothelin signaling axis activates osteopontin expression through PI3 kinase pathway in A375 melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118688.RAd09HyhOSIeAF8hzYqtbmY45-7-50NKf5yYVE6GPctoA130_provenance.
• NP118696.RAfV-U4xEGQ7Yo9wSlsBYt6MsC5dWuCijSHnnqhb7gHmw130_assertion description "[Chemoresistance of melanomas and neuroendocrine carcinomas of the skin cannot be explained by expression of the ABCG2-chemoresistance gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118696.RAfV-U4xEGQ7Yo9wSlsBYt6MsC5dWuCijSHnnqhb7gHmw130_provenance.
• NP118699.RASxAT9-6F488hLg0m-ymOZiYyR7CLWkauSPXQo_3kG-Y130_assertion description "[study identified two novel ABCA12 mutations in two unrelated non-bullous congenital ichthyosiform erythroderma patients; both patients presented with multiple skin malignancies including malignant melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118699.RASxAT9-6F488hLg0m-ymOZiYyR7CLWkauSPXQo_3kG-Y130_provenance.
• NP118700.RAVIZhmM3H_mKF2zzSQ-0ek6YuLUbUM4U0N_chmG_xDxA130_assertion description "[Human ribonuclease inhibitor gene has antiangiogenic and antitumor effects when expressed in hematopoietic cells in mouse melanoma models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118700.RAVIZhmM3H_mKF2zzSQ-0ek6YuLUbUM4U0N_chmG_xDxA130_provenance.
• NP118705.RARVvWmw-KI5oU5sur8P17JVLIB0rLVNDY2knVG9ITc4I130_assertion description "[Low levels of p27 in primary and metastatic melanoma cases may explain the high proliferation rate of such lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118705.RARVvWmw-KI5oU5sur8P17JVLIB0rLVNDY2knVG9ITc4I130_provenance.
• NP118710.RAS2wa-9TlPIl34JYWzaNPw4xC5_1oV6Wob2d7nyoU0jg130_assertion description "[We also demonstrate the expression and secretion of DJ-1 oncoprotein by uveal melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118710.RAS2wa-9TlPIl34JYWzaNPw4xC5_1oV6Wob2d7nyoU0jg130_provenance.
• NP118713.RATIjzxgaApXfSipBLasLc-CcuABqTj_AKCuYDaLxslu0130_assertion description "[Frameshift mutations of RIZ, but no point mutations, were found in RIZ1 exons in malignant melanomas with deletions in 1p36/has potential role in the multi-step tumor forming process of malignant melanoma of the skin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118713.RATIjzxgaApXfSipBLasLc-CcuABqTj_AKCuYDaLxslu0130_provenance.
• NP118733.RAd1uw-x8MNZ0csisnLN2TlWR_5VCcwhiveHttRXsIy6Q130_assertion description "[MMP2, MMP14, and MMP9 might be used as prognostic markers in patients with sinonasal and oral malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118733.RAd1uw-x8MNZ0csisnLN2TlWR_5VCcwhiveHttRXsIy6Q130_provenance.
• NP118735.RARUIS2W0o-eVYTvihS7N4UM-UVlC1DgSinor2i9LjUdM130_assertion description "[high serum MMP-8 levels in melanoma patients were significantly related to presence of vascular invasion (P = 0.001) in primary tumour, tumour ulceration (P = 0.003) and tumour bleeding (P = 0.033) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118735.RARUIS2W0o-eVYTvihS7N4UM-UVlC1DgSinor2i9LjUdM130_provenance.
• NP118737.RActy_mQ81yqBocJNFWNHiSZV6eOazklt8mGD2z8p2lOM130_assertion description "[In melanoma cells microtubule-dependent traffic of MMP2/MMP9-containing vesicles and exocytosis are critical steps for invasive behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118737.RActy_mQ81yqBocJNFWNHiSZV6eOazklt8mGD2z8p2lOM130_provenance.
• NP118741.RAc8dSja5phgEw0xHQQfsZ1hiVrtDbrCHmCn4YCS90YV4130_assertion description "[MMP2, MMP14, and MMP9 might be used as prognostic markers in patients with sinonasal and oral malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118741.RAc8dSja5phgEw0xHQQfsZ1hiVrtDbrCHmCn4YCS90YV4130_provenance.
• NP118744.RASeG5TFXY4_zt-xQrApcN28XOCcn1sWP492owbBkIcfU130_assertion description "[essential role for soluble factors, mainly IL-1alpha and bFGF, in the stimulation of dermal fibroblasts by human melanoma cells to secrete MMP-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118744.RASeG5TFXY4_zt-xQrApcN28XOCcn1sWP492owbBkIcfU130_provenance.
• NP118745.RAfsjkQ-uv9jzZAuhEVjlSP_llEJoLBsUvQT9xBLrtFKI130_assertion description "[MMP-1 produced from melanoma cells may play a role in tumor progression by both degrading matrix proteins and generating active growth factors such as TGF-beta in vivo ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118745.RAfsjkQ-uv9jzZAuhEVjlSP_llEJoLBsUvQT9xBLrtFKI130_provenance.
• NP118746.RAZJjlNrGJRWOaKPKk7BO_NTWm814rcVTXrfN_dx97GGk130_assertion description "[CD10 antigen is upregulated during the process of metastasis in melanomas/is rare in primary melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118746.RAZJjlNrGJRWOaKPKk7BO_NTWm814rcVTXrfN_dx97GGk130_provenance.
• NP118748.RAWro6D9ncszRGrLHbNuUJz6dGwmONAT8ZTJ1jzrqgCTI130_assertion description "[Evaluation of expression of PCNA and Ki-67 may provide an additional information about the progression of uveal melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118748.RAWro6D9ncszRGrLHbNuUJz6dGwmONAT8ZTJ1jzrqgCTI130_provenance.
• NP118750.RAW5O8rrrYN7wa8UyRLVcf2oikqAUlgkpt7aOSD8U3Mu8130_assertion description "[progesterone receptor expression in malignant melanoma is inversely correlated with PCNA ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118750.RAW5O8rrrYN7wa8UyRLVcf2oikqAUlgkpt7aOSD8U3Mu8130_provenance.
• NP118752.RAUQN7tAQmowApSLwyzTbLMB1eJtQZ26PczxjTcEB7z9A130_assertion description "[XAF1 expression in melanoma tissues was significantly reduced compared with benign melanocytic nevi ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118752.RAUQN7tAQmowApSLwyzTbLMB1eJtQZ26PczxjTcEB7z9A130_provenance.
• NP118757.RATG4ppXzOJ0di18zHqRhOf2Yyzp8lEeJZ7zuu3aTKhBU130_assertion description "[conclusion: decreased IGFBP-4 tumor expression might be a step in the progression from primary to metastatic melanoma; data lend support to a recently-described novel tumor suppressor role of secreting IGFBPs in melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118757.RATG4ppXzOJ0di18zHqRhOf2Yyzp8lEeJZ7zuu3aTKhBU130_provenance.
• NP118770.RATza7GFDcHL4OoOywNXRZQSOgNFnA5nI65Idh-Vy6coM130_assertion description "[MiTF regulates cellular response to reactive oxygen species by regulation of APE-1, and this may provide a mechanism of how MiTF is involved in melanoma carcinogenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118770.RATza7GFDcHL4OoOywNXRZQSOgNFnA5nI65Idh-Vy6coM130_provenance.
• NP118772.RARpHE27Tur3Bam0UmvSKoQngInaYXerwKY04_tTQ72XM130_assertion description "[findings show that in melanomas invasiveness can be regulated epigenetically by Mitf, via regulation of the DIAPH1 gene; Mitf, via regulation of Dia1, can both inhibit invasiveness & promote proliferation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118772.RARpHE27Tur3Bam0UmvSKoQngInaYXerwKY04_tTQ72XM130_provenance.
• NP118783.RAYjKawAXag_SqY-fEZaBwSkbtMzQpQE_MnWFfxeDydqs130_assertion description "[IFN-gamma, by down-regulating ligand expression, might facilitate escape of MHC class I-negative melanoma cells from NKG2D-mediated killing by NK cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118783.RAYjKawAXag_SqY-fEZaBwSkbtMzQpQE_MnWFfxeDydqs130_provenance.
• NP118784.RAUOfzLUgMvaOCPF3ARp9pGNwEcTIR8050nEpUZMnITsE130_assertion description "[IFN-beta in combination with TRAIL/Apo2L synergistically induces apoptosis and inhibits melanoma cell proliferation in vitro, at least in part by cleavage of the X-linked inhibitor of apoptosis (XIAP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118784.RAUOfzLUgMvaOCPF3ARp9pGNwEcTIR8050nEpUZMnITsE130_provenance.
• NP118789.RAQmYahjzB5ctuAUyEu_3Ohca1g_hOx0-M_ljnB_MI0iU130_assertion description "[PAX3-expressing melanomas may be less environmentally dependent and more genetically linked.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118789.RAQmYahjzB5ctuAUyEu_3Ohca1g_hOx0-M_ljnB_MI0iU130_provenance.
• NP118791.RAZySKhWU7DR33IYhPSTGmby0tMBlGlg75Kdf_OaaYukY130_assertion description "[IFIT2/GARG39 was identified as a microtubule-associated protein enriched in the mitotic spindle of mouse NIH3T3 and B16F10 melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118791.RAZySKhWU7DR33IYhPSTGmby0tMBlGlg75Kdf_OaaYukY130_provenance.
• NP118792.RAU1Ut4M51BTvcVG1PHc2lrjiEjvL-lhkuRH60NBj9FJs130_assertion description "[Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118792.RAU1Ut4M51BTvcVG1PHc2lrjiEjvL-lhkuRH60NBj9FJs130_provenance.
• NP118793.RAflRyLm506qf2KeBfuFoQExz9idDMO4_dydlmdNrPBaU130_assertion description "[findings delineate pleiotropic roles for MFG-E8 in the tumor microenvironment and raise the possibility that systemic MFG-E8 blockade might prove therapeutic for melanoma patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118793.RAflRyLm506qf2KeBfuFoQExz9idDMO4_dydlmdNrPBaU130_provenance.
• NP118796.RAVjF_eY5MuaPnhE4qk8TjwPSMn34msqbkFFBwj11Pfak130_assertion description "[High expression of plasminogen activator inhibitor, type I is associated with melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118796.RAVjF_eY5MuaPnhE4qk8TjwPSMn34msqbkFFBwj11Pfak130_provenance.
• NP118798.RAa17md5-CI6xuMWpAN6QNWqZ2isdmqa1o0nUJ-nN3P1A130_assertion description "[CD147 siRNA down-regulated the expression of vascular endothelial growth factor in malignant melanoma cells and reduced the migration of vascular endothelial cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118798.RAa17md5-CI6xuMWpAN6QNWqZ2isdmqa1o0nUJ-nN3P1A130_provenance.
• NP118823.RAcY91PvTD2TpCorih1zcqMdryipecQ7_cujbRkpTXouk130_assertion description "[Mitogen-activated protein kinase (MAPK) activity is subject to regulation even in BRAF/NRAS mutant melanoma cells and that high MAPK pathway signaling may be important only in distinct subsets of tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118823.RAcY91PvTD2TpCorih1zcqMdryipecQ7_cujbRkpTXouk130_provenance.
• NP118827.RAQdGTA-dkPg5I_b2_Gz0--cwMQbPCyLetcnlG77xBfFg130_assertion description "[Expression of p27Kip1 in melanoma is regulated by B-RAF at the mRNA level and via B-RAF control of Cks1/Skp2-mediated proteolysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118827.RAQdGTA-dkPg5I_b2_Gz0--cwMQbPCyLetcnlG77xBfFg130_provenance.
• NP118828.RAegz_aUWR3Xye1K9VzocCJuN4Gt_337xmQ9LgRv-Cv98130_assertion description "[BRCA1 downregulation in melanoma cells did not make them more aggressive and could lead to new therapeutic strategies for this tumor, which is so difficult to control once metastasized.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118828.RAegz_aUWR3Xye1K9VzocCJuN4Gt_337xmQ9LgRv-Cv98130_provenance.
• NP118832.RAQGtx0iUZTQnOWoPloJNMmw5ysxGRLHMdfpc-B0vcO0M130_assertion description "[CEACAM1 and alpha (v) beta (3) integrin are functionally interconnected with respect to the invasive growth of melanomas ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118832.RAQGtx0iUZTQnOWoPloJNMmw5ysxGRLHMdfpc-B0vcO0M130_provenance.
• NP118837.RAfvJX0B91cmoVZO6YSo5-mFIgHHym7-V-4dgzHg9hKT4130_assertion description "[Results demonstrate that p16ink4A-mimicking peptides can induce apoptosis in vitro and inhibit tumor growth in vivo in p16-defective, retinoblastoma protein-expressing human melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118837.RAfvJX0B91cmoVZO6YSo5-mFIgHHym7-V-4dgzHg9hKT4130_provenance.
• NP118838.RAWqHL0cbafTFsXUm5imaUZMdbJIYtUJKjGncVMd_Rxbo130_assertion description "[compromise of either p53 or Rb pathways during melanocyte transformation leads to up-regulation of survivin expression in melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118838.RAWqHL0cbafTFsXUm5imaUZMdbJIYtUJKjGncVMd_Rxbo130_provenance.
• NP118841.RAdL3HTf4A5bZSAahhIay7CUZN4rh0U04j6Oc4gz6_p08130_assertion description "[Determined kinetic parameters of beta 2-integrin and ICAM-1 bindings bindings between neutrophils and melanoma cells in a shear flow.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118841.RAdL3HTf4A5bZSAahhIay7CUZN4rh0U04j6Oc4gz6_p08130_provenance.
• NP118842.RARUhC0xRJYKGuO_78X5Uodp223AEqb-bZjPjhoWXBjI0130_assertion description "[Single Nucleotide Polymorphisms in intercellular adhesion molecule-1 is associated with cutaneous melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118842.RARUhC0xRJYKGuO_78X5Uodp223AEqb-bZjPjhoWXBjI0130_provenance.
• NP118846.RAcn2dLwd_8tWacUtEuT54M6kbkZOkHZc2aveDPt3yX2M130_assertion description "[MCAM expression doees not correlates with progression to advanced-stage melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118846.RAcn2dLwd_8tWacUtEuT54M6kbkZOkHZc2aveDPt3yX2M130_provenance.
• NP118849.RAY0EzYPJKh7hMXbE2ymmX-tEfF6YmOXnNMpe-btU_6wI130_assertion description "[Immunohistochemistry revealed a strong expression of melanocortin 1 receptor in all tested primary and metastatic melanomas, but also demonstrated low levels of expression in adrenal medulla, cerebellum, liver and keratinocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118849.RAY0EzYPJKh7hMXbE2ymmX-tEfF6YmOXnNMpe-btU_6wI130_provenance.
• NP118850.RAWxIH-b5mQ2yynxZf6lfGI-mOaLt3L3E2EA9IOmhJD54130_assertion description "[MC1R variant is associated with multiple primary melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118850.RAWxIH-b5mQ2yynxZf6lfGI-mOaLt3L3E2EA9IOmhJD54130_provenance.
• NP118858.RAXLXbcD2fOi9WZiVJA5cibyI9wnGeaiPBgumgQnMwS1I130_assertion description "[findings show that MC1R variants are strongly associated with BRAF mutations in non-chronic sun-induced damage melanomas; in this subtype, risk for melanoma associated with MC1R is due to increase in risk of developing melanomas with BRAF mutations ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118858.RAXLXbcD2fOi9WZiVJA5cibyI9wnGeaiPBgumgQnMwS1I130_provenance.
• NP118863.RAZVPyq3HgPbpWcyt3Lo4QdOHig1Xio5WSSdcuwU4X8Ds130_assertion description "[our study demonstrates increased concentrations of VEGF and Bcl-2, but not MMP-3, in serum of melanoma patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118863.RAZVPyq3HgPbpWcyt3Lo4QdOHig1Xio5WSSdcuwU4X8Ds130_provenance.
• NP118865.RAa4Xgmlhr5tX7U4Q-Cgsnrf30GJlLLKoGMI7wobjhlfU130_assertion description "[IGF1 promotes resistance to apoptosis in melanoma cells through an increased expression of BCL2, BCL-X (L), and survivin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118865.RAa4Xgmlhr5tX7U4Q-Cgsnrf30GJlLLKoGMI7wobjhlfU130_provenance.
• NP118866.RAX_W-4-aZZ0gJdT4fzs1ZxfHyftc8jzMuctJWUvWzuLo130_assertion description "[Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118866.RAX_W-4-aZZ0gJdT4fzs1ZxfHyftc8jzMuctJWUvWzuLo130_provenance.
• NP118868.RAQ-EaUy7DJ0xUg97xtDAb13bd2DGA3s-qrDKrprmklBo130_assertion description "[Notch signaling, which is implicated in melanoma progression, and Hairy and Enhancer of Split (HES1) play a role in MAP2 gene regulation during melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118868.RAQ-EaUy7DJ0xUg97xtDAb13bd2DGA3s-qrDKrprmklBo130_provenance.
• NP118869.RAe3gXuneo_6ZfR-x9RuocR3dmhMzIR278krEQw-v4IKc130_assertion description "[Bak function was found to be regulated in two distinct steps by two SAP kinases, MEKK1 and JNK1 when human melanoma cells were treated with cisplatin, and the two-step regulation may be important for control of mitochondrial factor release and apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118869.RAe3gXuneo_6ZfR-x9RuocR3dmhMzIR278krEQw-v4IKc130_provenance.
• NP118873.RAbM-YlEytf05W-UWr-z4zLMieMZCOaEsMhvMThvB_oLc130_assertion description "[Mutations at the beta2m gene level were detected in all cell lines in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118873.RAbM-YlEytf05W-UWr-z4zLMieMZCOaEsMhvMThvB_oLc130_provenance.
• NP118875.RAQHw0YmwTN1betHeqnrzWWSVJoqgEaCzyJNtD-vpNeFA130_assertion description "[MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118875.RAQHw0YmwTN1betHeqnrzWWSVJoqgEaCzyJNtD-vpNeFA130_provenance.
• NP118877.RAanAZdBB9pz0p4cKXBR0pr62R3gBvLYscaEK15Pl0tnI130_assertion description "[Axl pathway mediates increased survival of uveal melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118877.RAanAZdBB9pz0p4cKXBR0pr62R3gBvLYscaEK15Pl0tnI130_provenance.
• NP118881.RATLo--dgiPRSrsmQu2aklrrfAmoyhTGifNSADab22uv8130_assertion description "[down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118881.RATLo--dgiPRSrsmQu2aklrrfAmoyhTGifNSADab22uv8130_provenance.
• NP118882.RAYRH_gkqoRFDLvMT75TUumdRjBUPLA94YTo4hoFgfviM130_assertion description "[Data suggest that SPRY2, an inhibitor of ERK signaling, may be bypassed in melanoma cells either by down-regulation of its expression in WT BRAF cells, or by the presence of the BRAF mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118882.RAYRH_gkqoRFDLvMT75TUumdRjBUPLA94YTo4hoFgfviM130_provenance.
• NP118889.RAeX7e3EmDaIt3mYK7v7HJHxzQKVDAW1zfNsICQ2gvC2o130_assertion description "[IL-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118889.RAeX7e3EmDaIt3mYK7v7HJHxzQKVDAW1zfNsICQ2gvC2o130_provenance.
• NP118891.RAZLcXLRtg2bM-MRf4nWbbQ1K3OhDTY9Bnef41vCTIE4s130_assertion description "[study identified a group of melanomas with low-activity BRAF mutations (G469E- and D594G) that are reliant upon CRAF-mediated survival activity ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118891.RAZLcXLRtg2bM-MRf4nWbbQ1K3OhDTY9Bnef41vCTIE4s130_provenance.
• NP118895.RAUEfXua4tB7a2au9c3307H1z2bNwNb0YPjjj-JaGFUY8130_assertion description "[Endothelin signaling axis activates osteopontin expression through PI3 kinase pathway in A375 melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118895.RAUEfXua4tB7a2au9c3307H1z2bNwNb0YPjjj-JaGFUY8130_provenance.
• NP118898.RASeLBXoHALaOgBecVrXc6SGDiMLV-GIstnH3GGaMvufs130_assertion description "[Transient re-expression of SPARC in SPARC-downregulated melanoma cells reverted extracellular N-CAD, CLU, and HSP27 to levels similar to those in the control.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118898.RASeLBXoHALaOgBecVrXc6SGDiMLV-GIstnH3GGaMvufs130_provenance.
• NP118900.RAQRHVNAXo58ePQK1vS6gSjcF4821ptMy9HVd60bqRUW4130_assertion description "[FCRL/FREB may function in melanocytes and melanoma and may be useful for development of diagnostic methods for various pigment disorders and immunotherapy of melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118900.RAQRHVNAXo58ePQK1vS6gSjcF4821ptMy9HVd60bqRUW4130_provenance.
• NP118907.RAWPpeM3iAo_PlyKI-ECLPmhI3jp1ReyL8nIJomvGh5CM130_assertion description "[p130Cas and paxillin function as effectors of GD3-mediated signaling, leading to such malignant properties as rapid cell growth and invasion in melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118907.RAWPpeM3iAo_PlyKI-ECLPmhI3jp1ReyL8nIJomvGh5CM130_provenance.
• NP118916.RASKxnUEG4Whavhcx31gb1DQK5EgSSnC2iIFc0m7h6Z7c130_assertion description "[Genetic variants (i.e., TaqI t protective allele and FokI f risk allele) in VDR may alter risk of cutaneous melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118916.RASKxnUEG4Whavhcx31gb1DQK5EgSSnC2iIFc0m7h6Z7c130_provenance.
• NP118922.RAfViFlcH6N3dMpQ-cmRswkSqYEATp6ik11yhFNW_3IeQ130_assertion description "[Downregulated by aberrant methylation of Tms1 is associated with melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118922.RAfViFlcH6N3dMpQ-cmRswkSqYEATp6ik11yhFNW_3IeQ130_provenance.
• NP118923.RAfUl8pOTd0nGn7sOITPPLzOmIAqwP-E4B8QsVYfW0yoM130_assertion description "[CDK11p60 can contribute to apoptosis by direct signalling at the mitochondria, thereby amplifying Fas-induced apoptosis in melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118923.RAfUl8pOTd0nGn7sOITPPLzOmIAqwP-E4B8QsVYfW0yoM130_provenance.
• NP118928.RAUjjCQfvTWPyPMorJ6VOK-PK7P6W0Qb19WTwSA_kiSYc130_assertion description "[BRMS1 has subsequently been shown to suppress metastasis, but not tumorigenicity of human melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118928.RAUjjCQfvTWPyPMorJ6VOK-PK7P6W0Qb19WTwSA_kiSYc130_provenance.
• NP118933.RAdsT0DJxK1F4K8eV6069P1GACesLVsm7WfkO002gxpJs130_assertion description "[Data suggest that p33 (ING1) cooperates with p53 in UVB-induced apoptosis via the mitochondrial cell death pathway in melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118933.RAdsT0DJxK1F4K8eV6069P1GACesLVsm7WfkO002gxpJs130_provenance.
• NP118936.RAaP93_ImFNs5dofoc-XTayHQfYQTa7zIBVEwuqQxi6xc130_assertion description "[gastrin has pleiotropic effects in melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118936.RAaP93_ImFNs5dofoc-XTayHQfYQTa7zIBVEwuqQxi6xc130_provenance.
• NP118937.RAQVgLHSNkBTzCJ6Zzab6BvXYyaoKCBRdD_uc5sQY4v5g130_assertion description "[ILK knockdown decreased the invasion ability of melanoma cells and the formation of anchorage-independent colonies in soft agar ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118937.RAQVgLHSNkBTzCJ6Zzab6BvXYyaoKCBRdD_uc5sQY4v5g130_provenance.
• NP118940.RAWWQI-Nvoi4h9FdUn_rcAkFxfTZsMnMD017mVJ30DPkY130_assertion description "[Multivariate logistic regression analysis revealed that CASP8 D302 H, CASP8 -652 6N del, and CASP10 I522L were independent risk factors for cutaneous melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118940.RAWWQI-Nvoi4h9FdUn_rcAkFxfTZsMnMD017mVJ30DPkY130_provenance.
• NP118954.RATxtwvZvA1gQaxLCsnuL0SG6HI9vM_l7guq1H5JZocd4130_assertion description "[progression of melanoma is associated with changes in CDK-2 expression level ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118954.RATxtwvZvA1gQaxLCsnuL0SG6HI9vM_l7guq1H5JZocd4130_provenance.
• NP118957.RAY02IpYv5WpjUNG4qvlfwN06HGRjbUe4Dsqj8o7x7Hwo130_assertion description "[Significantly elevated epidermal growth factor receptor is associated with metastatic malignant melanoma patients with an inverse correlation between EGF-R and IL-6 levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118957.RAY02IpYv5WpjUNG4qvlfwN06HGRjbUe4Dsqj8o7x7Hwo130_provenance.
• NP118962.RAQKCUbwwliJm5bRivYp_-cCZuLA8UCL9r7Kc4Lb0hIcs130_assertion description "[Down-regulation of endothelin receptor B correlated with death from metastatic disease in uveal melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118962.RAQKCUbwwliJm5bRivYp_-cCZuLA8UCL9r7Kc4Lb0hIcs130_provenance.
• NP118963.RAV8IT4nEuIyiTOojSH_d6GfouJoa5XHgPNm63DMHMQ7U130_assertion description "[Increased expression of the tumor suppressor PLZF in malignant melanomas is associated with long-term patient survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118963.RAV8IT4nEuIyiTOojSH_d6GfouJoa5XHgPNm63DMHMQ7U130_provenance.
• NP118967.RASZH4jNOFFumXf1_6XmOfcKC7gvT628eM-gY3bjKj6Ec130_assertion description "[These results suggest the activation of proMMP-2 as an important event in the process of uveal melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118967.RASZH4jNOFFumXf1_6XmOfcKC7gvT628eM-gY3bjKj6Ec130_provenance.
• NP118968.RAf9zMCs2moqTbAY52Y97yMig804jefetyzE8JrOK2jeA130_assertion description "[an interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118968.RAf9zMCs2moqTbAY52Y97yMig804jefetyzE8JrOK2jeA130_provenance.
• NP118973.RAdKB51r4_rZwX4QYSvEAdaonLJefR8Ftf24xiI89zALY130_assertion description "[TAP1 and TAP2 expression restores both antigen presentation and immunogenicity in A375 melanoma cells and concomitantly increases IL-12 and IFN-gamma production in tumor antigen-specific cytotoxic T lymphocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118973.RAdKB51r4_rZwX4QYSvEAdaonLJefR8Ftf24xiI89zALY130_provenance.

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