Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence IL28B+polymorphisms+are+markers+of+therapy+response+and+are+influenced+by+genetic+ancestry+in+chronic+hepatitis+C+patients+from+an+admixed+population. assertion.
- assertion asSentence Polymorphisms+near+IL28B+are+independently+associated+with+serologic+response+to+PEG-IFN+in+patients+with+HBeAg-positive+chronic+hepatitis+B. assertion.
- assertion asSentence In+non-alcoholic+fatty+liver+disease+patients%2C+IL28B+rs12979860+CC+genotype%2C+together+with+PNPLA3+rs738409+GG%2C+is+associated+with+the+severity+of+liver+damage. assertion.
- assertion asSentence IL-29+exerts+IFN-beta-independent+protection+in+alveolar+type+II+cells+through+direct+activation+of+antiviral+genes+during+influenza+A+virus+infection. assertion.
- assertion asSentence The+G72%2FG30+complex+is+considered+as+one+of+the+most+promising+candidate+genes+for+both+schizophrenia+and+bipolar+disorder. assertion.
- assertion asSentence Biogenesis+of+lysosome-related+organelles+complex-1+%28BLOC-1%29+subunit+2+%28BLOS2%29.BLOC-1+is+required+for+the+biogenesis+of+melanosomes+and+platelet+dense+granules. assertion.
- assertion asSentence Dilated+cardiomyopathy+in+patients+with+RBM20+mutations+is+associated+with+advanced+disease. assertion.
- assertion asSentence Association+of+H19+promoter+methylation+with+the+expression+of+H19+gene+in+adrenocortical+tumors. assertion.
- assertion asSentence Imprinting+defects+associated+with+disturbed+spermatogenesis.+methylation+of+the+H19+gene+changed+in+oligozoospermic+patients. assertion.
- assertion asSentence Biallelic+expression+of+H19+gene+exists+in+some+cases+at+early+stage+of+normal+pregnancy+%26+changes+into+monoallelic+expression+near+10+weeks+of+gestation. assertion.
- assertion asSentence The+high+morbility+of+the+FGR+with+hypertentive+disorder+complicating+pregnancy+has+no+relationships+with+the+imprinting+status+of+IGF-II+and+H19+genes. assertion.
- assertion asSentence Peptide-specific+transfer+of+N-acetylgalactosamine+to+O-linked+glycans+by+the+glycosyltransferases+beta1%2C4-N-acetylgalactosaminyl+transferase+3+%28beta4GalNAc-T3%29+and+beta4GalNAc-T4. assertion.
- assertion asSentence KCNRG+suppresses+K%2B+channel+activity+in+human+prostate+cell+line+LNCaP. assertion.
- assertion asSentence TSEN54+mutation+causes+a+severe+form+of+pontocerebellar+hypoplasia+type+1+in+a+family. assertion.
- assertion asSentence Evolutionary+recombination+hotspot+around+the+GSDML-GSDM+locus+is+closely+linked+to+oncogenomic+recombination+hotspot+around+the+PPP1R1B-STARD3-TCAP-PNMT-PERLD1-ERBB2-C17orf37-GRB7+amplicon+at+human+chromosome+17q12. assertion.
- assertion asSentence The+GSDMA+%28rs7212938%29+and+GSDMB+%28rs7216389%29+polymorphisms+are+associated+with+asthma+susceptibility+and+intermediate+asthma+phenotypes. assertion.
- assertion asSentence Expression+and+function+of+NaCT+in+a+cell+line+and+in+primary+hepatocytes. assertion.
- assertion asSentence WDR62+mutations+found+in+individuals+with+microcephaly+associated+with+a+broad+range+of+malformations+of+cortical+development. assertion.
- assertion asSentence Mutations+in+WDR62+gene+leads+to+microcephaly+and+other+brain+malformations. assertion.
- assertion asSentence UNC80+functions+as+a+scaffold+for+Src+kinases+in+NALCN+channel+function. assertion.
- assertion asSentence MicroRNA-510+target+site+of+the+3%27UTR+of+HTR3A+and+HTR3E+are+associated+with+the+irritable+bowel+syndrome+with+diarrhea. assertion.
- assertion asSentence The+COOH-terminal+NES+and+Src+homology+2+target+motifs+play+key+roles+in+Dok-7%2FMuSK+signaling+for+neuromuscular+synaptogenesis. assertion.
- assertion asSentence Dok-7+activates+the+muscle+receptor+kinase+MuSK+and+shapes+synapse+formation. assertion.
- assertion asSentence Sequencing+of+DOK-7+in+seronegative+myasthenia+gravis+patients+reveals+no+mutations. assertion.
- assertion asSentence Both+hCox18p+and+hCox19p+present+significant+amino+acid+identity+with+the+corresponding+yeast+polypeptides+and+reveal+highly+conserved+functional+domains. assertion.
- assertion asSentence SH3PXD2B+is+a+scaffold+protein+that+plays+a+key+role+in+regulating+the+actin+cytoskeleton+via+Src+and+cortactin. assertion.
- assertion asSentence APG9L2+is+highly+expressed+in+placenta+%28trophoblast+cells%29+and+pituitary+gland+of+adult+tissues. assertion.
- assertion asSentence The+gene+NYS4+is+associated+with+acquired+vestibulocerebellar+type+nystagmus. assertion.
- assertion asSentence No+association+of+trace+amine+receptor+genes+with+bipolar+disorder. assertion.
- assertion asSentence Rab7b+is+required+for+normal+lysosome+function%2C+and%2C+in+particular%2C+it+is+an+essential+factor+for+retrograde+transport+from+endosomes+to+the+trans-Golgi+network. assertion.
- assertion asSentence SNORD115-1+gene+is+imprinted%2C+with+preferential+expression+from+the+paternal+allele+in+the+brain. assertion.
- assertion asSentence CHX10+regulates+RdCVF+promoter+activity+in+the+inner+retina. assertion.
- assertion asSentence Mutations+in+VSX2+represent+an+important+cause+of+autosomal+recessive+microphthalmia+in+consanguineous+pedigrees. assertion.
- assertion asSentence Loss+of+FAM5C+is+associated+with+tongue+squamous+cell+carcinoma. assertion.
- assertion asSentence Phenotypic+heterogeneity+in+the+Gray+platelet+syndrome+extends+to+the+expression+of+TREM+family+member%2C+TLT-1. assertion.
- assertion asSentence Tenascin-C+promotes+melanoma+progression+by+maintaining+the+ABCB5-positive+side+population. assertion.
- assertion asSentence ABCB5+mediates+5-FU+resistance+in+cultured+human+colorectal+cancer+cells+and+affected+tumor+growth+in+xenografts. assertion.
- assertion asSentence The+E-cadherin-repressed+hNanos1+gene+induces+tumor+cell+invasion+by+upregulating+MT1-MMP+expression. assertion.
- assertion asSentence Among+the+three+gustatory+regions+innervated+by+peripheral+gustatory+neurons+in+the+geniculate+ganglion%2C+transgenic+Pkd1l3+is+expressed+in+the+foliate+papillae%2C+not+in+the+fungiform+papillae+or+palate. assertion.
- assertion asSentence Mutations+in+RD3+are+a+very+rare+cause+of+Leber%27s+congenital+amaurosis+%28LCA%29+associated+with+an+extremely+severe+form+of+retinal+dystrophy. assertion.
- assertion asSentence The+unusual+evolutionary+history+of+the+IRGM+locus+and+the+important+role+of+the+IRGM+gene+in+autophagy+and+Crohn%27s+disease+in+response+to+pathogenesis. assertion.
- assertion asSentence Single-nucleotide+polymorphism+rs4958847+in+the+IRGM+gene+correlated+very+significantly+with+frequency+of+surgery+in+patients+with+ileocolonic+Crohn%27s+disease. assertion.
- assertion asSentence IRGM+rs4958847+polymorphism+influences+susceptibility+to+gastric+cancer%2C+mainly+for+the+intestinal+type. assertion.
- assertion asSentence Apart+from+the+complexity+of+its+regulation%2C+alterations+in+both+CTNNA3+and+LRTMM3+are+implicated+in+human+disease. assertion.
- assertion asSentence Human+HCN1+hyperpolarization+activated+current+%28Ih%29+amplitude+is+rapidly+enhanced+after+establishment+of+the+whole-cell+configuration+in+HEK293+cells. assertion.
- assertion asSentence HCN1+channels+make+an+important+contribution+to+the+maintenance+of+spontaneous+burst+activity+in+embryonic+cortical+neuron+cultures. assertion.
- assertion asSentence The+connexin30.2%2FCX31.3+shares+functional+properties+with+pannexin+%28hemi%29+channels+rather+than+gap+junction+channels+of+other+Connexins. assertion.
- assertion asSentence A+detailed+mapping+of+the+breakpoints+revealed+intragenic+microdeletions+affecting+the+coding+regions+of+RGSL2%2C+RGSL1. assertion.
- assertion asSentence Missense+mutations+in+RGSL1+gene+is+associated+with+breast+cancer. assertion.
- assertion asSentence Both+yeast+and+human+pol+eta+synthesize+past+the+3%27-%28m%29C+CPD+in+a+%3E99%25+error-free+manner%2C+consistent+with+the+highly+water-exposed+nature+of+the+active+site. assertion.
- assertion asSentence GLT6D1+is+a+susceptibility+locus+for+periodontitis. assertion.
- assertion asSentence Up-regulation+of+beta3Gn-T8+in+differentiated+cells+increases+poly-N-acetyllactosamine+chains+by+activating+intrinsic+beta3Gn-T2. assertion.
- assertion asSentence Neucrin+is+a+unique+secreted+Wnt+antagonist+that+is+predominantly+expressed+in+developing+neural+tissues. assertion.
- assertion asSentence A+specific+intronic+PEAR1+gene+variant+is+ientified+that+associated+with+greater+platelet+aggregability+and+protein+expression. assertion.
- assertion asSentence As+a+major+regulator+of+Cdc25A%2C+Dub3+is+an+example+of+a+transforming+ubiquitin+hydrolase+that+subverts+a+key+component+of+the+cell+cycle+machinery%2C+promoting+oncogenic+transformation. assertion.
- assertion asSentence MHF1+and+MHF2+form+a+compact+tetramer+to+which+FANCM-F+binds+through+a+%27dual-V%27+shaped+structure. assertion.
- assertion asSentence Malin+is+an+E3+ubiquitin+ligase+that+ubiquitinates+and+promotes+the+degradation+of+laforin. assertion.
- assertion asSentence Regulation+of+glycogen+synthesis+by+the+laforin-malin+complex+is+modulated+by+the+AMP-activated+protein+kinase+complex+pathway. assertion.
- assertion asSentence Malin+is+related+to+TRIM32+at+both+the+phylogenetic+and+functional+level. assertion.
- assertion asSentence IL-31+is+important+in+atopic+dermatitis+pathophysiology. assertion.
- assertion asSentence GPRA+gene+polymorphism+is+associated+with+asthma+in+a+large+german+population. assertion.
- assertion asSentence GPRA+gene+is+associated+with+asthma+and+bronchial+hyperreactivity. assertion.
- assertion asSentence Association+of+G-protein-coupled+receptor+154+with+asthma+and+total+IgE+in+a+population+of+the+Caribbean+coast+of+Colombia. assertion.
- assertion asSentence Ther+neuropeptide+S+receptor+genotype+is+associated+with+increased+amygdala+responsiveness+to+fear-relevant+stimuli. assertion.
- assertion asSentence Autonomous+silencing+is+the+main+mechanism+controlling+gamma-gene+expression+in+the+adult. assertion.
- assertion asSentence Both+ARMS2+polymorphism+and+complement+factor+H+polymorphism+are+independently+associated+with+progression+of+age-related+macular+degeneration. assertion.
- assertion asSentence CDK-Speedy%2FRingo+C+complexes+positively+regulate+cell+cycle+progression+during+the+late+S+and+G%282%29+phases+of+the+cell+cycle. assertion.
- assertion asSentence SET8+plays+a+role+in+controlling+G1%2FS+transition+by+blocking+lysine+acetylation+in+histone+through+binding+to+H4+N-terminal+tail. assertion.
- assertion asSentence The+miR-502-binding+site+single-nucleotide+polymorphism+in+the+3%27-UTR+of+SET8+modulates+SET8+expression+and+contributes+to+the+early+development+of+breast+cancer. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+C2CD4B+is+associated+with+type+2+diabetes. assertion.
- assertion asSentence Mutations+in+C2orf71+cause+autosomal-recessive+retinitis+pigmentosa. assertion.
- assertion asSentence LIN28B+plays+an+important+role+in+radiation+responses+of+lung+cancer+cells+through+inhibiting+let-7g+microRNA+processing+and+increasing+translation+of+KRAS. assertion.
- assertion asSentence Distinct+variants+at+LIN28B+influence+growth+in+height+from+birth+to+adulthood. assertion.
- assertion asSentence Under+diabetic+conditions%2C+expression+and%2For+activities+of+PDX-1+and+MafA+in+beta-cells+are+reduced+%5BREVIEW%5D. assertion.
- assertion asSentence CTRP13+reduces+glucose+output+in+hepatocytes+by+inhibiting+the+mRNA+expression+of+gluconeogenic+enzymes%2C+glucose-6-phosphatase+and+the+cytosolic+form+of+phosphoenolpyruvate+carboxykinase. assertion.
- assertion asSentence Significant+transmission+disequilibrium+%28P%3D0.0010%29+occurred+between+the+haplotype+TAACG+of+rs2111701-+rs4020123-+rs4903696-+rs11159318-+rs177216+in+primary+congenital+glaucoma. assertion.
- assertion asSentence Tag+single+nucleotide+polymorphisms+near+the+BLID+and+LOC399959+genes+are+not+susceptibility+loci+for+high+myopia+in+the+Chinese+Han+population. assertion.
- assertion asSentence Cytoplasmic+RGS7%2AGbeta5%2AR7BP+heterotrimers+and+RGS7%2AGbeta5+heterodimers+are+equivalently+inefficient+regulators+of+G+protein-coupled+receptor+signaling+relative+to+plasma+membrane-bound+heterotrimers+bearing+palmitoylated+R7BP. assertion.
- assertion asSentence SOX2+enhancers+SRR1+and+SRR2+are+each+differentially+methylated+and+acetylated%2C+on+a+temporal+basis%2C+contributing+to+the+generation+of+neuron-+and+astrocyte-specific+epigenomes+from+a+common+progenitor+cell. assertion.
- assertion asSentence PDP1%2FPPAPDC2+is+a+functional+isoprenoid+diphosphate+phosphatase. assertion.
- assertion asSentence Serine+protease+of+Kazal-type+%28SPINK6%29+expressed+in+normal+human+skin+is+a+potent+natural+inhibitor+of+Kallikrein-related+peptidases%2C+KLK12+and+KLK13. assertion.
- assertion asSentence Heterodimerization+controls+localization+of+Duox-DuoxA+NADPH+oxidases+in+airway+cells. assertion.
- assertion asSentence Up-regulation+and+sustained+activation+of+Stat1+are+essential+for+interferon-gamma+%28IFN-gamma%29-induced+dual+oxidase+2+%28Duox2%29+and+dual+oxidase+A2+%28DuoxA2%29+expression+in+human+pancreatic+cancer+cell+lines. assertion.
- assertion asSentence The+decreased+let-7+expression+is+associated+with+C.+parvum-induced+up-regulation+of+TLR4+in+infected+cells. assertion.
- assertion asSentence hnRNP+A1+and+KSRP+have+antagonistic+roles+in+the+post-transcriptional+regulation+of+let-7a+expression. assertion.
- assertion asSentence Let-7i+is+associated+with+colorectal+cancer+metastasis. assertion.
- assertion asSentence Higher+expression+levels+of+miR-100+is+associated+with+childhood+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence The+tumour-suppressor+miRNAs+let-7+and+mir-101+target+MYCN+and+inhibit+proliferation+and+clonogenic+growth+of+MYCN-amplified+neuroblastoma+cells. assertion.
- assertion asSentence miR-101+DNA+copy+loss+is+a+prominent+subtype+specific+event+in+lung+cancer. assertion.
- assertion asSentence Low+miR-106a+is+associated+with+lymph+recurrence+in+squamous+cell+esophageal+carcinoma. assertion.
- assertion asSentence The+expression+of+miR-17-3p+and+miR-106a+is+regulated+by+TNFalpha+and+lipopolysaccharides+in+HeLa+cells. assertion.
- assertion asSentence miR-106a+can+increase+p53+expression+via+E2F1+inhibition. assertion.
- assertion asSentence PSD-95%2FNR2B+interaction+is+more+sensitive+to+disruption+by+Tat-NR2B9c+than+PSD-95%2FNR2A+coupling+in+live+cultured+hippocampal+neurons. assertion.
- assertion asSentence Changes+in+molecular+composition+support+an+important+role+of+NR2A+subunits+in+the+developmental+plasticity+of+fast-spiking+GABAergic+circuits+during+critical+period. assertion.
- assertion asSentence NR2A+and+NR2B+subunits+play+different+roles+in+motor+neuron+chronic+glutamate+excitotoxicity+in+amyotrophic+lateral+sclerosis. assertion.
- assertion asSentence Inhibition+of+the+GluN2A+subtype+reduces+long+term+potentiation+to+the+same+level+in+NCAM-deficient+and+wild-type+%28NCAM-positive%29+littermate+mice+and+abolishes+the+rescue+by+d-cycloserine+in+NCAM-deficient+mice. assertion.
- assertion asSentence NMDA+receptor+NR2B+subunit+over-expression+increases+cerebellar+granule+cell+migratory+activity. assertion.
- assertion asSentence NR2B-containing-N-methyl-D-aspartate+glutamatergic+receptors+are+expressed+at+a+higher+level+in+the+extra-synaptic+area+of+pyramidal+neurons+from+glycine+transporter+GlyT1%2B%2F-+compared+to+wild-type+mice. assertion.
- assertion asSentence Hippocampal+and+extra-hippocampal+NR2B+containing+NMDA+receptors+critically+contribute+to+spatial+performance. assertion.
- assertion asSentence Deficits+in+neural+cell+adhesion+molecule+%28NCAM%29%2Fpolysialic+acid+increase+GluNR2B+receptor-mediated+transmission+in+the+CA1+region+of+the+hippocampus. assertion.