Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP118978.RAa5z_TyYSWtnToml2NYdTyUsbkRdMq7ACrgHtqz5n8sA130_assertion description "[Cyr61 is a hypoxia-inducible angiogenesis factor in malignant melanoma with tumor stage-dependent expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118978.RAa5z_TyYSWtnToml2NYdTyUsbkRdMq7ACrgHtqz5n8sA130_provenance.
- NP118982.RAZ3jo58qaIDZRWwKXDM2CqblMBHosHADnrz7rmycVDSE130_assertion description "[identifies a novel strategy developed by melanoma cells to evade NK cell-mediated immune surveillance based on the intracellular sequestration of immature forms of MICA in the endoplasmic reticulum ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118982.RAZ3jo58qaIDZRWwKXDM2CqblMBHosHADnrz7rmycVDSE130_provenance.
- NP118994.RAfUmP3UYjdgOtjupZt3V9vlefkNqlZ8BPlHOu_KhGrQA130_assertion description "[Cleavage of Bid is required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118994.RAfUmP3UYjdgOtjupZt3V9vlefkNqlZ8BPlHOu_KhGrQA130_provenance.
- NP118998.RARCji_fL8GFJUiU_55f0k_U2W33bmUM2g_Ct3VdZQapw130_assertion description "[Results validate the role of RGS1 as a novel prognostic marker for melanoma given its impact on the survival associated with melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP118998.RARCji_fL8GFJUiU_55f0k_U2W33bmUM2g_Ct3VdZQapw130_provenance.
- NP119003.RAZ4cT9QiP-OskBPy7z2z9HZX4C9bq5aXvpK0Bqsf0cbc130_assertion description "[Data suggest there is no defect in the JAK/STAT pathway in the tested melanoma cell lines, and that interferon resistance must be mediated through other components.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119003.RAZ4cT9QiP-OskBPy7z2z9HZX4C9bq5aXvpK0Bqsf0cbc130_provenance.
- NP119005.RAX8fJloH8cSTlWAqqp1mqNQTXV-gTe5GFiPBxMHGrRsA130_assertion description "[The expression of three messengers coding for SAT-1, SAT-2 and GalNAcT-1 in human samples of intestinal cancer and some cell lines (breast cancer and melanomas), was evaluated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119005.RAX8fJloH8cSTlWAqqp1mqNQTXV-gTe5GFiPBxMHGrRsA130_provenance.
- NP119009.RATSYBeudACtSvS1UXFy4ABPT36boZWs-PaAwbUF5Otwk130_assertion description "[Analysis of loss of heterozygosity in melanoma resection specimens ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119009.RATSYBeudACtSvS1UXFy4ABPT36boZWs-PaAwbUF5Otwk130_provenance.
- NP119010.RAYLcL5NuntpsMxhCKRM0ZKcYEO4JGAjV6kTX2m6vQ6gM130_assertion description "[The alpha-MSH-induced differentiation of COLO 853 human melanoma cells is associated with decreased pRB phosphorylation and accumulation of cells in the G (1) phase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119010.RAYLcL5NuntpsMxhCKRM0ZKcYEO4JGAjV6kTX2m6vQ6gM130_provenance.
- NP119011.RAe0H7erwR9dTU9F5OlWquL5DIyjtSCFDlnyL4BrNq5To130_assertion description "[The transformation of melanocytes to melanoma cells is characterised by abnormal proliferation due to cell cycle alterations/occurs through alterations in the retinoblastoma (Rb) and p53 tumour suppressor pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119011.RAe0H7erwR9dTU9F5OlWquL5DIyjtSCFDlnyL4BrNq5To130_provenance.
- NP119015.RAYxDrWd27eiHU-ar5axC6kl1ylT4bnCRqaxPTTgEJqAw130_assertion description "[Overexpression of Rap1GAP in melanoma cells blocks Rap1 activation and extracellular signal-regulated kinase (ERK) phosphorylation and inhibits melanoma cell proliferation and survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119015.RAYxDrWd27eiHU-ar5axC6kl1ylT4bnCRqaxPTTgEJqAw130_provenance.
- NP119023.RAcOf13QXPZcaFUJAEuFp0v_zTAB4xncUJRuH3-UFAmj0130_assertion description "[Data may suggest a possible role of the overexpression of cyclin D1 in the tumorigenesis of uveal malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119023.RAcOf13QXPZcaFUJAEuFp0v_zTAB4xncUJRuH3-UFAmj0130_provenance.
- NP119027.RAdJD9zsobCd6Q3Ao6lkSz5pMW_a8ZLJjQv1GTw1eNGgg130_assertion description "[the SLC45A2 variant p.Phe374Leu was significantly and strongly protective for melanoma; MC1R and SLC45A2 variants had additive effects on melanoma risk, and after adjusting for pigmentation characteristics, the risk was persistent ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119027.RAdJD9zsobCd6Q3Ao6lkSz5pMW_a8ZLJjQv1GTw1eNGgg130_provenance.
- NP119028.RAcm__BHiZBPhRIAySDoj-nyAjBTXp5aAPM6YkkRdBmBc130_assertion description "[direct role of WT1 in melanoma proliferation, which might be mediated via Nestin and Zyxin ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119028.RAcm__BHiZBPhRIAySDoj-nyAjBTXp5aAPM6YkkRdBmBc130_provenance.
- NP119036.RAUSvWw8LVCiShiGXKAkJ_5PCURax-mFIYLE42KxxM1I0130_assertion description "[Increased vascular endothelial growth factor C mRNA expression correlates with stage of progression in patients with melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119036.RAUSvWw8LVCiShiGXKAkJ_5PCURax-mFIYLE42KxxM1I0130_provenance.
- NP119045.RAV9sBFa3mAw1YgIGmpL8C_OAhhvsqM_4MsK3evaUrvsk130_assertion description "[LOH at hOGG1 gene is associated with melanoma in situ and atypical melanocytic hyperplasia, suggesting that the hOGG1 gene may play a role in melanocytic tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119045.RAV9sBFa3mAw1YgIGmpL8C_OAhhvsqM_4MsK3evaUrvsk130_provenance.
- NP119048.RAXbtCn9PTW_y9DXrz9-9QvmI_eW4WX6q8cVVXzGJBokk130_assertion description "[EIncreased expression of cyclooxygenase-2 is associated with cutaneous melanoma progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119048.RAXbtCn9PTW_y9DXrz9-9QvmI_eW4WX6q8cVVXzGJBokk130_provenance.
- NP119049.RASWvTtwmn4VRbK-WIXoAxxSo-rZcgAB-0ia59vcw7klE130_assertion description "[Data show that vitamin C suppresses proliferation of the human melanoma cell line SK-MEL2 via the down-regulation of IGF-II production and IGF-IR expression, which is followed by the activation of p38 MAPK and the inhibition of COX-2 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119049.RASWvTtwmn4VRbK-WIXoAxxSo-rZcgAB-0ia59vcw7klE130_provenance.
- NP119050.RAfTxU-ukf6llSjkZ4vWv-mcS2o6b_TLQ9lMRv5jqmTrk130_assertion description "[Mixed-cell tumours, representing majority of uveal melanomas, may be further subclassified according to COX-2 expression, a marker of poor prognosis/in uveal melanoma should be further elucidated/inhibitors may be adjuvant treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119050.RAfTxU-ukf6llSjkZ4vWv-mcS2o6b_TLQ9lMRv5jqmTrk130_provenance.
- NP119054.RAQXnSb29cHMzRcPXVfVob-DH0mScUN3HPemQ2-2MNVBg130_assertion description "[These results indicate that the inhibition of cyclooxygenase-2 can lead to the regression of disseminated skin melanoma metastases, even after failure of chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119054.RAQXnSb29cHMzRcPXVfVob-DH0mScUN3HPemQ2-2MNVBg130_provenance.
- NP119055.RAZ4drjUqlilY0J5LFFeMtjv_oaqLC9wkgkfJqOIszHJA130_assertion description "[MIA may promote the detachment of radial and vertical growth phase melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119055.RAZ4drjUqlilY0J5LFFeMtjv_oaqLC9wkgkfJqOIszHJA130_provenance.
- NP119057.RATztkkLcMrTrvwBV1gr_0izK8U98evSSAGjPX1OyOQ7A130_assertion description "[The MIA protein enhances the migration of melanocytes and promotes melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119057.RATztkkLcMrTrvwBV1gr_0izK8U98evSSAGjPX1OyOQ7A130_provenance.
- NP119060.RAUzKwDD7GRcBssInpkz34Xhwsbi5uH9zXniuJ3pkPS0k130_assertion description "[MIA serum level is the ideal test for screening the skin melanoma spread to sentinel lymph nodes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119060.RAUzKwDD7GRcBssInpkz34Xhwsbi5uH9zXniuJ3pkPS0k130_provenance.
- NP119062.RAQFlJyeVapxcBIFDNBVpxA9usIZ7SOrDBedwmcF5Y7yE130_assertion description "[MIA may contribute to immunosuppression frequently seen in malignant melanomas by inhibiting cellular antitumor immune reactions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119062.RAQFlJyeVapxcBIFDNBVpxA9usIZ7SOrDBedwmcF5Y7yE130_provenance.
- NP119064.RAYd-NDWv73kNIuljNvzYlVnpWGym3wtLOCgfajgTC9Yo130_assertion description "[OPN acts downstream of PI3K in melanoma and PTEN loss contributes to melanoma development ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119064.RAYd-NDWv73kNIuljNvzYlVnpWGym3wtLOCgfajgTC9Yo130_provenance.
- NP119070.RAac9q96VPSdTKj65I_JeyMvfB4FewrQu21cevF0lPrZE130_assertion description "[catK may play an important role in melanoma invasion and metastasis by mediating intracellular degradation of matrix proteins after phagocytosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119070.RAac9q96VPSdTKj65I_JeyMvfB4FewrQu21cevF0lPrZE130_provenance.
- NP119071.RAT6YMUVllEUPW3bm9rbvZE8UjOIdWsOFoFAHJPa0SPj4130_assertion description "[Skp2 is required for downregulation of p27Kip1 levels in melanoma cells; Skp2 expression level regulates melanoma cell growth, most likely through effects on cell proliferation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119071.RAT6YMUVllEUPW3bm9rbvZE8UjOIdWsOFoFAHJPa0SPj4130_provenance.
- NP119078.RAckjHD2Stb2Mm2qnnk71KuUrDlGou-CJINr2DL6By2rg130_assertion description "[The expression pattern of TASK-3 in Melanoma cells is determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119078.RAckjHD2Stb2Mm2qnnk71KuUrDlGou-CJINr2DL6By2rg130_provenance.
- NP119086.RAeH-5BLeXqY-7ZOjM8aR2rnzSv0xzqn2o_OstYLFfFsg130_assertion description "[IGFBP2 expression increases from benign and dysplastic nevi to primary and metastatic melanomas and suggests that it may play a role in melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119086.RAeH-5BLeXqY-7ZOjM8aR2rnzSv0xzqn2o_OstYLFfFsg130_provenance.
- NP119089.RAZfFjMMnKsTFpNILivzp-R0a9W-vPq0lpeilUwLNMGhA130_assertion description "[Advanced melanoma cells may escape from BMP7-induced inhibition through concomitant aberrant expression of Noggin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119089.RAZfFjMMnKsTFpNILivzp-R0a9W-vPq0lpeilUwLNMGhA130_provenance.
- NP119092.RAcG-za5acQRoQxnBWDaKTz3SWgphetV38-i4jYEA0V0Y130_assertion description "[ABCB8 confers resistance through the protection of mitochondrial DNA from doxorubicin-induced DNA damage in a melanoma cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119092.RAcG-za5acQRoQxnBWDaKTz3SWgphetV38-i4jYEA0V0Y130_provenance.
- NP119097.RAZxmnCXF9QfwqhkkGV65zU0g96frGURSw8EpvUx9L-qQ130_assertion description "[These results indicate that APITD1 is not the tumor suppressor gene on 1p36 responsible for the negative prognostic effect in uveal melanoma with concurrent loss of chromosome arm 1p, region 36, and chromosome 3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119097.RAZxmnCXF9QfwqhkkGV65zU0g96frGURSw8EpvUx9L-qQ130_provenance.
- NP119099.RARqd0edV1J9pnn8gV1qR5bi4ogiu6AC392Wfz1K7RTfQ130_assertion description "[study supports a significant role of the ID1 protein in melanoma progression and patient prognosis; inverse relation between ID1 and TSP-1 expression support an important role of ID1 in regulation of this complex multitarget protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119099.RARqd0edV1J9pnn8gV1qR5bi4ogiu6AC392Wfz1K7RTfQ130_provenance.
- NP119104.RAa1MbjI63UeHkdYyEkQ1TjjC0MFJjv-EeUVrNNFYVc7I130_assertion description "[Mcl-1 is an important factor contributing to the chemoresistance of human melanoma in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119104.RAa1MbjI63UeHkdYyEkQ1TjjC0MFJjv-EeUVrNNFYVc7I130_provenance.
- NP119106.RASK-F_5e0HAy_nQArmKYM_iXNXUytDPfS0ucRlXVVgfI130_assertion description "[Vasculature in tumours and in retina and choroid of all melanoma-affected and normal eyes showed intense MUC18 immunostaining.observations further suggest a role for MUC18 in uveal melanoma growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119106.RASK-F_5e0HAy_nQArmKYM_iXNXUytDPfS0ucRlXVVgfI130_provenance.
- NP119108.RARRz5TCzVujlY91kyJjN8-muB9AHOp9z9M-rLErRQJ5g130_assertion description "[Natural cytotoxic T cell-defined reactivity is detected against Bcl-xL in peripheral blood leukocytes from patients with breat cancer and melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119108.RARRz5TCzVujlY91kyJjN8-muB9AHOp9z9M-rLErRQJ5g130_provenance.
- NP119109.RAVUBAZuKrf5XXiLwpuArfJYQNHSRl4t7sfyIR-PP39ZQ130_assertion description "[inhibitory effect on uveal melanoma cells using an Hsp90 inhibitor, 17-allylamino-17-demethoxygeldanamycin (17-AAG), in uveal melanoma cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119109.RAVUBAZuKrf5XXiLwpuArfJYQNHSRl4t7sfyIR-PP39ZQ130_provenance.
- NP119116.RAfN1r3tTK4RdSP83Mlb4oh67NhmIvHuRvryx7RWJMmJI130_assertion description "[investigation of the expression of Sox10 in other human tumors and in a number of gliomas/expression was restricted to gliomas and melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119116.RAfN1r3tTK4RdSP83Mlb4oh67NhmIvHuRvryx7RWJMmJI130_provenance.
- NP119120.RAZNLMeoq5jEw0uh5U_HdVbvBUdLjb_D_16mcj_S-oPm0130_assertion description "[Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in mouse melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119120.RAZNLMeoq5jEw0uh5U_HdVbvBUdLjb_D_16mcj_S-oPm0130_provenance.
- NP119124.RAeEsvwYcnXoBVUCBhylOjARBHnmQJi7SFPmSMzRJSxfg130_assertion description "[results reveal that a functional TRPM8 protein is expressed in human melanoma cells to involve the mechanism underlying tumor progression via the Ca (2+) handling pathway, providing us with a novel target of drug development for malignant melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119124.RAeEsvwYcnXoBVUCBhylOjARBHnmQJi7SFPmSMzRJSxfg130_provenance.
- NP119137.RAZmxQIq-_bbRCMlWpFHmyU8NiSjA2FYRHXHyF_-ro3lU130_assertion description "[HLA-E expression and shedding are normal features of melanocytes, which are conserved in melanoma cells of primary tumors, but become dependent on IFN-gamma induction after metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119137.RAZmxQIq-_bbRCMlWpFHmyU8NiSjA2FYRHXHyF_-ro3lU130_provenance.
- NP119138.RARFLr7GAalpDjVqnbUIXSpEA1CrgsgKnSBsMWDapAd10130_assertion description "[Measurement of Melan-A, gp100, MAGE-3, MIA and tyrosinase represents a prognostic factor and a method for early detection of metastasis and treatment response of melanoma patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119138.RARFLr7GAalpDjVqnbUIXSpEA1CrgsgKnSBsMWDapAd10130_provenance.
- NP119143.RAQMkH9E0Zz8xQpPBznD05xDhmWosSLO10wbo04e_3KDQ130_assertion description "[the expression of Melan-A/MART-1 in patient-derived cell cultures may help to identify a group of melanoma patients with prolonged survival ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119143.RAQMkH9E0Zz8xQpPBznD05xDhmWosSLO10wbo04e_3KDQ130_provenance.
- NP119144.RAeEn4stGp6z0CXPJ4zenVRFqlyt07gPQXlNibsYV6WAc130_assertion description "[results show a complex pattern of changes in the expression of Melan-A in melanomas depending on the location of melanoma cells within individual skin layers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119144.RAeEn4stGp6z0CXPJ4zenVRFqlyt07gPQXlNibsYV6WAc130_provenance.
- NP119146.RAUcy9a3pgCcL1VPEh17SJFRxBtW7YyQAJCkbIvDrjXtg130_assertion description "[HLA-DRB1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119146.RAUcy9a3pgCcL1VPEh17SJFRxBtW7YyQAJCkbIvDrjXtg130_provenance.
- NP119157.RAcFSK6ocWCXVFl5mHI-9dwuNcsQefZLQ4hxhn1IjGh-8130_assertion description "[Melanoma cells express the low-affinity (p75NTR) and the high-affinity tyrosine kinase NT receptors (Trk).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119157.RAcFSK6ocWCXVFl5mHI-9dwuNcsQefZLQ4hxhn1IjGh-8130_provenance.
- NP119160.RAYnfRg0Qnv4mzOdPT70wtLFr0pk8WbUtZYiZGcvB3ht0130_assertion description "[NT-3, NT-4, and nerve growth factor (NGF) induce cell migration in melanoma, with a stronger effect on metastatic cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119160.RAYnfRg0Qnv4mzOdPT70wtLFr0pk8WbUtZYiZGcvB3ht0130_provenance.
- NP119166.RAfAkEVUAL261nQCIcWrI2DYTuAVBUiilAlSn_nfjQILM130_assertion description "[flotillin-2 has a role in lymph node metastasis in melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119166.RAfAkEVUAL261nQCIcWrI2DYTuAVBUiilAlSn_nfjQILM130_provenance.
- NP119170.RAfrI5bFjJjY6h3qos6nFKkEBCL5U3xkcuQLtKvJna54E130_assertion description "[FASL secretion was analyzed in melanoma cells in culture/secretion was associated with secretory vesicles upon melanoma activation with phytohemagglutonins or alpha-MSH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119170.RAfrI5bFjJjY6h3qos6nFKkEBCL5U3xkcuQLtKvJna54E130_provenance.
- NP119172.RAaGP84YmBTGhGmU5KKujjudwgEK2LX_Yxi2sv51KgFJ8130_assertion description "[results strongly implicate a pivotal role of cell-matrix interactions for the regulation of cathepsin B localization and activity in melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119172.RAaGP84YmBTGhGmU5KKujjudwgEK2LX_Yxi2sv51KgFJ8130_provenance.
- NP119179.RAdWiai06yPag-Nkaht3ymasg-nS2atCOl1DmS1dAIKMY130_assertion description "[expression of CD95 in 15/17 human melanoma cell lines analysed, but complete lack of CD95 ligand (CD95L) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119179.RAdWiai06yPag-Nkaht3ymasg-nS2atCOl1DmS1dAIKMY130_provenance.
- NP119180.RAb0SLMatLWRcQQI6vRNEEsQd14eTkHiZdEmvpD6cWAEo130_assertion description "[Introduction of CD8 alpha down-regulates the production of major T helper (Th) type 2 cytokines and may induce differentiation of tumor-specific Th1 cells to improve the clinical potential of T cell receptor (TCR) gene transfer to treat melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119180.RAb0SLMatLWRcQQI6vRNEEsQd14eTkHiZdEmvpD6cWAEo130_provenance.
- NP119193.RAfUE3JTTl7MD4j1H6xnvGfmBwKNZfLid9--chCSn5ZYU130_assertion description "[p38 has a role in apoptosis in human melanoma cells by modulating depolarization of mitochondrial membrane potential ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119193.RAfUE3JTTl7MD4j1H6xnvGfmBwKNZfLid9--chCSn5ZYU130_provenance.
- NP119194.RARgwXKvzlW5xTonaEeqBuHR0Ly00d8PXDVzvmU642IHs130_assertion description "[The KISS1 metastasis suppressor gene inhibits metastasis in both in vivo melanoma and breast carcinoma models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119194.RARgwXKvzlW5xTonaEeqBuHR0Ly00d8PXDVzvmU642IHs130_provenance.
- NP119197.RAaHhx1nRp8OExEmbA7HYtZEuSrIcSvwFvYqlayNDyf7g130_assertion description "[Post-translational modification of CD44s represents the principal regulatory mechanism of CD44s-mediated functions in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119197.RAaHhx1nRp8OExEmbA7HYtZEuSrIcSvwFvYqlayNDyf7g130_provenance.
- NP119199.RAUSWzSqW8v_UlLS0QwgYPcHj749PoqM5mG7QgUTT84ZI130_assertion description "[In melanoma, expression of activated Cdc42 induces a mesenchymal-amoeboid transition and increases cell invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119199.RAUSWzSqW8v_UlLS0QwgYPcHj749PoqM5mG7QgUTT84ZI130_provenance.
- NP119200.RATtb1QRY-HzH6y2HABqck7E8-4XzSSQy62xJCvbYbTe8130_assertion description "[E-cadherin may sensitize human melanoma cells towards apoptosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119200.RATtb1QRY-HzH6y2HABqck7E8-4XzSSQy62xJCvbYbTe8130_provenance.
- NP119201.RAZHkexDXVvl1tI3mZypLhx4ufZBKzHy5RsIHpmd53MjY130_assertion description "[E-cadherin may have a role in inhibition melanoma invasiveness by epigallocatechin-3-gallate ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119201.RAZHkexDXVvl1tI3mZypLhx4ufZBKzHy5RsIHpmd53MjY130_provenance.
- NP119207.RAZC8Wsq3W-JSR0I2oULKaS0rjywFB6K7Jhg51Uw-7K2g130_assertion description "[In human melanoma cells, MFG-E8 knockdown attenuated Akt and Twist signaling and thereby compromised tumor cell survival, EMT, and invasive ability ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119207.RAZC8Wsq3W-JSR0I2oULKaS0rjywFB6K7Jhg51Uw-7K2g130_provenance.
- NP119208.RAaHrLghVDwdiWQfo-ZVQyg82keHT22zTDq9Eea7F4AiI130_assertion description "[Toll-like receptors 2 highly expressed on human melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119208.RAaHrLghVDwdiWQfo-ZVQyg82keHT22zTDq9Eea7F4AiI130_provenance.
- NP119212.RAcuQG1jojN3r_ZC6SkAymw25xTJoxkuBhjl5RQs4CZgU130_assertion description "[Increased expression of TSP1 is associated with an aggressive angiogenic phenotype in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119212.RAcuQG1jojN3r_ZC6SkAymw25xTJoxkuBhjl5RQs4CZgU130_provenance.
- NP119215.RAQB4nwqVurHfGOOuakwlcm1eSGCtxyb5Mk29M8oa_avU130_assertion description "[Human melanoma cells release elevated levels of glutamate, implying a possible autocrine loop via GRM1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119215.RAQB4nwqVurHfGOOuakwlcm1eSGCtxyb5Mk29M8oa_avU130_provenance.
- NP119221.RAVRn28Jmix5G8s66lS502IKXOaGe0lbYmBufiRAEMthA130_assertion description "[CTLA4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119221.RAVRn28Jmix5G8s66lS502IKXOaGe0lbYmBufiRAEMthA130_provenance.
- NP119222.RAS7-53AGg9tkpCbQeGOW9zyGVZj1yRCttJOnJ8k9ohes130_assertion description "[The data suggest a novel role for tyrosine phosphorylation of N-cadherin by Src family kinases in the regulation of beta-catenin association during transendothelial migration of melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119222.RAS7-53AGg9tkpCbQeGOW9zyGVZj1yRCttJOnJ8k9ohes130_provenance.
- NP119226.RAa-F0tYJAnJR7B6UfeBSLJrAUPACkd0AspH2oWLYYfUQ130_assertion description "[The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119226.RAa-F0tYJAnJR7B6UfeBSLJrAUPACkd0AspH2oWLYYfUQ130_provenance.
- NP119230.RAS5W9HXh7XwFhc70X2ND4bzSDnh0S_0XRY92GyRoyjVA130_assertion description "[Bim plays an essential role in synergistic induction of apoptosis by SBHA and TRAIL in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119230.RAS5W9HXh7XwFhc70X2ND4bzSDnh0S_0XRY92GyRoyjVA130_provenance.
- NP119239.RAT0Di0Ral5RoFHNw1uZa8OufPbAMHlLnh9om6JFK0a6w130_assertion description "[The ability of CRH to induce POMC expression in cultured melanoma cells; in CRH positive melanomas, seven out of nine cases (78%) of primary melanoma, and 7 out of 12 cases (58%) of MetM showed colocalization of CRH and POMC peptides ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119239.RAT0Di0Ral5RoFHNw1uZa8OufPbAMHlLnh9om6JFK0a6w130_provenance.
- NP119241.RAdbzw6QYOq8hTFxw4Xf1Un3atJtCURXfWUl3LyUZn88E130_assertion description "[effect of platelet-derived CD40L on the tissue factor activity of human CD40-positive melanoma cells and monocytes ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119241.RAdbzw6QYOq8hTFxw4Xf1Un3atJtCURXfWUl3LyUZn88E130_provenance.
- NP119250.RAexSpdDLiUAaglewhvS_HGdy6J3orp3PHpp4GriTSXsM130_assertion description "[constituitively activated in choroidal melanoma cell lines, independent of Ras, and regulated by B-RafV599E ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119250.RAexSpdDLiUAaglewhvS_HGdy6J3orp3PHpp4GriTSXsM130_provenance.
- NP119254.RAamKqLW6-tSo4gcnM1MXxmVGOpKqO1T6jEOvxAJnZJjY130_assertion description "[Results conclude about important role of APC alterations for melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119254.RAamKqLW6-tSo4gcnM1MXxmVGOpKqO1T6jEOvxAJnZJjY130_provenance.
- NP119256.RASAUe719Xff7xXxUOeQHN-JkSbj8QwUhqOlyfABshp5I130_assertion description "[Genetic and epigenetic alterations of the APC gene were studied in malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119256.RASAUe719Xff7xXxUOeQHN-JkSbj8QwUhqOlyfABshp5I130_provenance.
- NP119259.RAbZuJF7gN-HBy0N7AVKyHU7MpulPuJM1Ubs6Y_uSM3uY130_assertion description "[These data support the involvement in melanoma growth and survival of a VEGF-dependent internal autocrine loop mechanism, at least in vitro.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119259.RAbZuJF7gN-HBy0N7AVKyHU7MpulPuJM1Ubs6Y_uSM3uY130_provenance.
- NP119266.RAXZLRd5PmH3xP5CQZPinAu4S2R6hLIz1vBpJ7NcOe0uY130_assertion description "[Polymorphisms in NF-kappaB1 and NF-kappaBIalpha genes is associated with melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119266.RAXZLRd5PmH3xP5CQZPinAu4S2R6hLIz1vBpJ7NcOe0uY130_provenance.
- NP119268.RAWf_od5I_yPxFCNZgyDtP0OlwPWAN4niiEeL96m3zEBI130_assertion description "[TGF-beta 1 suppresses not only the acquisition but also expression of effector function on memory CD8 T cells and tumor-infiltrating lymphocytes reactive against melanoma and can hinder the therapeutic benefits of cancer vaccination and immunotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119268.RAWf_od5I_yPxFCNZgyDtP0OlwPWAN4niiEeL96m3zEBI130_provenance.
- NP119271.RAYnUDXNrXiOdPvKoOqRhn3FuTOSl3u4XiNR5ZsdwRQhw130_assertion description "[Modulation of triple-helical stability and subsequent melanoma cellular responses by single-site substitution of fluoroproline derivatives of collagen alpha1 (IV).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119271.RAYnUDXNrXiOdPvKoOqRhn3FuTOSl3u4XiNR5ZsdwRQhw130_provenance.
- NP119274.RAWKLkKnOqDgigfKBaU_-T2rokWUaViATffK0f5uY3sQE130_assertion description "[Expression in melanoma cells is regulated by NSAIDs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119274.RAWKLkKnOqDgigfKBaU_-T2rokWUaViATffK0f5uY3sQE130_provenance.
- NP119279.RAR-A_mb9jG9-E7z5PZt9s5XDjDxgWYoJYUcXaZ43f6F4130_assertion description "[N-RAS (Q61K) and B-RAF (V600E) contribute to melanoma's resistance to apoptosis in part by downregulating Bim expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119279.RAR-A_mb9jG9-E7z5PZt9s5XDjDxgWYoJYUcXaZ43f6F4130_provenance.
- NP119280.RAXIfQxBPzdioh5uobShXcoXqw8r60ERXCYMswyNRQJJE130_assertion description "[HGF signaling process from Gab1 to PI3K is negatively regulated by PKC-betaII, and its loss is critical for melanoma cells to gain invasive potential.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119280.RAXIfQxBPzdioh5uobShXcoXqw8r60ERXCYMswyNRQJJE130_provenance.
- NP119283.RAeJQsJzLlQ4GaqeoZMOPNw8qZbwzaWvJM7Po7oMn9SVQ130_assertion description "[NY-ESO-1 is more frequently expressed in metastatic than in primary malignant melanoma and its expression is associated with thicker primary lesions and a higher frequency of metastatic disease, indicative of a worse prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119283.RAeJQsJzLlQ4GaqeoZMOPNw8qZbwzaWvJM7Po7oMn9SVQ130_provenance.
- NP119284.RAQ0e7v32uENVSsmyrwNvvj3LdXqLG3Qj_CdMPtBqTSyY130_assertion description "[thymosin beta4 is a determinant of AdoMetDC-induced transformed phenotype and invasiveness; up-regulation of thymosin beta4 found in ras-transformed fibroblasts and metastatic human melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119284.RAQ0e7v32uENVSsmyrwNvvj3LdXqLG3Qj_CdMPtBqTSyY130_provenance.
- NP119285.RAcgXZ9t_paU6W7Ij5i5KgjAcsSReqMbk_v3ZN4yxIKw8130_assertion description "[down-regulation of KAI1/CD82 mRNA expression in human melanoma cell lines is related to LOH or allelic imbalance, but not to methylation of the KAI1/CD82 gene region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119285.RAcgXZ9t_paU6W7Ij5i5KgjAcsSReqMbk_v3ZN4yxIKw8130_provenance.
- NP119291.RAUtc94BCVHTsYwJjRL6HJsX4vWMxd3zF0Bc_c-aQhQ_Q130_assertion description "[Our results provide novel insights into the role of HER3 in melanoma and point out new possibilities for therapeutic intervention ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119291.RAUtc94BCVHTsYwJjRL6HJsX4vWMxd3zF0Bc_c-aQhQ_Q130_provenance.
- NP119300.RAYuqE9GYGF5dy2GWZg6wkn4ftOYWmFa9GeOxJru9_vr8130_assertion description "[loss of Hugl-1 expression contributes to melanoma progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119300.RAYuqE9GYGF5dy2GWZg6wkn4ftOYWmFa9GeOxJru9_vr8130_provenance.
- NP119302.RAUpMPcoy-iJBNAsx6OCHefSqUYKuzuIXtstGXw3ku-Ug130_assertion description "[Preferential role of in cytotoxic T lymphocyte migration toward melanoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119302.RAUpMPcoy-iJBNAsx6OCHefSqUYKuzuIXtstGXw3ku-Ug130_provenance.
- NP119306.RAVO-nSHfmVKRPtPH0W9tYRbnehQzuIRwxO8BT2GbEWXE130_assertion description "[melanoma metastasis is associated with increased expression of the syntenin gene which may participate in signal transduction and cell adhesion via the multifunctional protein-binding properties of its tandem PDZ domains ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119306.RAVO-nSHfmVKRPtPH0W9tYRbnehQzuIRwxO8BT2GbEWXE130_provenance.
- NP119309.RAeoHEFv28J3jd8PYbb_ikJX3Ddiouh00xJQwn1NeBqMg130_assertion description "[Lack of thrombomodulin expression due to methylation of the promoter CpG island is associated with malignant melanoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119309.RAeoHEFv28J3jd8PYbb_ikJX3Ddiouh00xJQwn1NeBqMg130_provenance.
- NP119313.RAcsllWq3TqGoP7z6tAsxhd2XdE7f2wPQLvDHACbZkz_I130_assertion description "[proportions of FOXP3-bearing lymphocytes were higher in vertical than in radial growth phase, as well as in late than in early melanoma stages ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119313.RAcsllWq3TqGoP7z6tAsxhd2XdE7f2wPQLvDHACbZkz_I130_provenance.
- NP119315.RAfquF5jUHrgD-QF90KWjGewlq76E2fHSGRvBIP3es0Mc130_assertion description "[C-kit protein expression correlated with activating mutations indicating the pertinent role of the proto-oncogene KIT in the tumorigenesis of oral musosal melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119315.RAfquF5jUHrgD-QF90KWjGewlq76E2fHSGRvBIP3es0Mc130_provenance.
- NP119316.RAUQ4b4TcquRTZicunnGKIYwMHrxAWzs06n70tDEmhXEk130_assertion description "[the presence of c-Kit and VEGF overexpression is associated with the presence of second primary tumors in patients with melanoma; overexpression of c-Kit is more likely to be seen in the superficial spreading type ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119316.RAUQ4b4TcquRTZicunnGKIYwMHrxAWzs06n70tDEmhXEk130_provenance.
- NP119320.RAWtSxsEGFtHouydtiVYgNkK2ThLrJyzfBJl2KquvYdNk130_assertion description "[Results suggest an important role of methylthioadenosine phosphorylase inactivation in the development of melanomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119320.RAWtSxsEGFtHouydtiVYgNkK2ThLrJyzfBJl2KquvYdNk130_provenance.
- NP119322.RAbZj_V6n3gGO9lZnorwIYXtus88hde4TvekXNg1g6ECo130_assertion description "[Mutations of the NF1 gene may occasionally play a role in the pathogenesis of uveal melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119322.RAbZj_V6n3gGO9lZnorwIYXtus88hde4TvekXNg1g6ECo130_provenance.
- NP119325.RAcevSKX19iONWSAmMUDjXueEdUpN02dRqJN6Nm2Mocgk130_assertion description "[Down-regulation of ARMS results in inhibition of anchorage-independent growth in soft agar and restrictive growth of melanoma in severe combined immunodeficient mice ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119325.RAcevSKX19iONWSAmMUDjXueEdUpN02dRqJN6Nm2Mocgk130_provenance.
- NP119329.RASENGu1Mfk_fBKyAib8XFV3kt-vd5-Ef4EjMIijIG0ng130_assertion description "[HspB8 overload causes melanoma growth arrest and apoptosis through TAK1 activation ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119329.RASENGu1Mfk_fBKyAib8XFV3kt-vd5-Ef4EjMIijIG0ng130_provenance.
- NP119330.RAcobS3iW_xDYydgyiPngOh_H2wlAgP3c0ZAYpo6qDGXg130_assertion description "[In CRH positive melanomas, seven out of nine cases (78%) of primary melanoma, and 7 out of 12 cases (58%) of MetM showed colocalization of CRH and POMC peptides/induced POMC mRNA expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119330.RAcobS3iW_xDYydgyiPngOh_H2wlAgP3c0ZAYpo6qDGXg130_provenance.
- NP119331.RAUd6ZfkIHFLroE4KChCV08gDOaOzD_qmB7FnLn_xiMBs130_assertion description "[P2X (7) receptor has an antiapoptotic function in melanoma cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119331.RAUd6ZfkIHFLroE4KChCV08gDOaOzD_qmB7FnLn_xiMBs130_provenance.
- NP119347.RAWuIU_RAAg86qlYXsL2DezaX8tQBXqZ7EbgjMAOMpEhg130_assertion description "[lower EphB6 expression has a role in melanoma progression to metastatic disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119347.RAWuIU_RAAg86qlYXsL2DezaX8tQBXqZ7EbgjMAOMpEhg130_provenance.
- NP119351.RAfcsMn8rBxZ4tWSiBU804IFkptNALHUA5UwORfNiCBhs130_assertion description "[secretion of RANTES by human leukocyte antigen-A2-restricted tyrosinase-specific cytotoxic T lymphocyte in the context of human melanoma cell killing ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119351.RAfcsMn8rBxZ4tWSiBU804IFkptNALHUA5UwORfNiCBhs130_provenance.
- NP119367.RAegNYnSzOysuFWfJcISYxi-kZaxsUCeGeFXXCtjBF_jU130_assertion description "[ALDH1 can be a dermal biomarker for atopic dermatitis disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119367.RAegNYnSzOysuFWfJcISYxi-kZaxsUCeGeFXXCtjBF_jU130_provenance.
- NP119375.RARr0osknpH3DgfIbUfYHiekXSGM6CoKYqrhKxvalXv90130_assertion description "[KIAA0603 is likely to be a Rab GAP that participates in the regulation of activated T cells in atopic dermatitis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119375.RARr0osknpH3DgfIbUfYHiekXSGM6CoKYqrhKxvalXv90130_provenance.
- NP119384.RAWMIa2AWV41RM_ckjx2mDnaK_pOEh9YznLAF9GN93WgI130_assertion description "[serum levels correlate with disease severity specific for atopic dermatitis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119384.RAWMIa2AWV41RM_ckjx2mDnaK_pOEh9YznLAF9GN93WgI130_provenance.
- NP119385.RAXiFrpZe21hpR3nTi1auBeJjQtCcBsoTgdu4s9U1cO9k130_assertion description "[findings indicate TARC and MDC are actively involved in pathogenesis of atopic dermatitis and their expression, opposite to that of eotaxin, is strongly associated with clinical picture of atopic dermatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119385.RAXiFrpZe21hpR3nTi1auBeJjQtCcBsoTgdu4s9U1cO9k130_provenance.