Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP119800.RAQJzZRIbnwZtK1ORoFpMJTItf9YS8Avzgl1OUa_V_7Bc130_assertion description "[Overexpression of FHL2 increases the tumorigenicity of glioblastoma cells in nude mice and decreases the mRNA levels of p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119800.RAQJzZRIbnwZtK1ORoFpMJTItf9YS8Avzgl1OUa_V_7Bc130_provenance.
- NP119801.RAdpKm3zGzwF0RtPELYwvXcOfiLGHy4SuZa-mD0b30mvo130_assertion description "[Mxi1 can act as a tumour suppressor in human glioblastomas through a molecular mechanism involving the transcriptional down-regulation of cyclin B1 gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119801.RAdpKm3zGzwF0RtPELYwvXcOfiLGHy4SuZa-mD0b30mvo130_provenance.
- NP119803.RATP6D-hi-1mEZQ5HPzKUZ9rUzt60LkQsAAX6HIjS2Kj0130_assertion description "[Oligodendroglial and astrocytic gliomas show EMP3 hypermethylation and aberrant expression/and secondary glioblastomas have distinct genetic profiles and also differ in their epigenetic aberrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119803.RATP6D-hi-1mEZQ5HPzKUZ9rUzt60LkQsAAX6HIjS2Kj0130_provenance.
- NP119808.RAU7eu5RweRddW3f0BDLJhenMvDibFI8mUyzd3Q4biLuo130_assertion description "[Repression of BIM is favored in human glioblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119808.RAU7eu5RweRddW3f0BDLJhenMvDibFI8mUyzd3Q4biLuo130_provenance.
- NP119809.RAd8Y7VL5HJKmVpL30bYL5sne6jAl0R8YoKISmcj7Y_tk130_assertion description "[Lovastatin-induced cell death occurs in correlation with significantly increased levels of the BH3-only protein, Bim in susceptible glioblastoma cell lines; up-regulation of Bim was directly associated with increased incidence of apoptosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119809.RAd8Y7VL5HJKmVpL30bYL5sne6jAl0R8YoKISmcj7Y_tk130_provenance.
- NP119812.RAWYl8jaDKDX6qg2I_Dw6Nr55C29ear3iJOdiWQbo4UyQ130_assertion description "[upregulation in glioblastoma multiforme ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119812.RAWYl8jaDKDX6qg2I_Dw6Nr55C29ear3iJOdiWQbo4UyQ130_provenance.
- NP119819.RAdqAL_Rgv5v7DHbtTUgj3olcqt3wQq6eMNh6LodPxypg130_assertion description "[DNA-PK has a positive role in the regulation of apoptosis in human glioblastomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119819.RAdqAL_Rgv5v7DHbtTUgj3olcqt3wQq6eMNh6LodPxypg130_provenance.
- NP119822.RAW2S31eVAueaxnqwoWApJDss9L4LiTSiLnSBDERvtayA130_assertion description "[NDRG2 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of primary glioblastomas, but not in lower grade astrocytomas and secondary glioblastomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119822.RAW2S31eVAueaxnqwoWApJDss9L4LiTSiLnSBDERvtayA130_provenance.
- NP119823.RAczPikP2Osd53GogLNZytjylc07uJYxws9EiIOwiuDXY130_assertion description "[Down-Regulation of N-Myc downstream-regulated gene 2 is associated with glioblastoma ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119823.RAczPikP2Osd53GogLNZytjylc07uJYxws9EiIOwiuDXY130_provenance.
- NP119824.RAdr4l8NBjc3HtofzbmmIsqa0pgm1gPmuoUs8jba4ohus130_assertion description "[Pleiotrophin failed to activate anaplastic lymphoma kinase (ALK) in neuroblastoma/glioblastoma cells expressing this receptor/is still an orphan receptor in vertebrates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119824.RAdr4l8NBjc3HtofzbmmIsqa0pgm1gPmuoUs8jba4ohus130_provenance.
- NP119826.RAbjNBB9-eA_z5XO5HYfUF3jpUYzkSpLNQ9JRUBTf3aF8130_assertion description "[Alpha-B-crystallin associates with the perinuclear Golgi in a cell cycle-dependent fashion in U373 human glioblastoma cells/appears in the nascent Golgi immediately following cytokinesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119826.RAbjNBB9-eA_z5XO5HYfUF3jpUYzkSpLNQ9JRUBTf3aF8130_provenance.
- NP119829.RAfd2kgg9laSW0VDy7NFeMAtbblU0k6KR-4JM0igQ2Y5E130_assertion description "[Ang1 regulates Glioblastoma Multiforme (GBM) vascularity in a VEGF-A dependent manner, synergizing the initial pro-angiogenic response that is triggered by VEGF-A and promoting the vascular growth of GBM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119829.RAfd2kgg9laSW0VDy7NFeMAtbblU0k6KR-4JM0igQ2Y5E130_provenance.
- NP119834.RAfEChAcrDbCzTOmmDAOEZpMuADj5CGXZww4W5BPBNF7c130_assertion description "[Serum AHSG concentration, measured before starting treatment, predicts survival in patients with glioblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119834.RAfEChAcrDbCzTOmmDAOEZpMuADj5CGXZww4W5BPBNF7c130_provenance.
- NP119839.RAaCfWUUqw7BkX0On-lMCJss0kwKMTZWSbNw_d2z5nZ9c130_assertion description "[p53 disruption has a dramatic effect on how glioblastoma cells process topoisomerase I inhibitor-mediated DNA damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119839.RAaCfWUUqw7BkX0On-lMCJss0kwKMTZWSbNw_d2z5nZ9c130_provenance.
- NP119841.RAe-viLGX_4mezOuki4LJX10IvFilT5UX_0Um6MTHu7cU130_assertion description "[The KLC1 56836CC variant exerts a significant protective effect on the occurrence of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119841.RAe-viLGX_4mezOuki4LJX10IvFilT5UX_0Um6MTHu7cU130_provenance.
- NP119843.RAebYKpOOsPYmrKJ4jzu72dM-WUqJtfZRo8p1lPd0mSmg130_assertion description "[Review describes the role of alpha 4-integrin in the pathophysiology of demyelinating diseases and the findings which led to the targeting of alpha 4-integrin for the treatment of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119843.RAebYKpOOsPYmrKJ4jzu72dM-WUqJtfZRo8p1lPd0mSmg130_provenance.
- NP119854.RASKijLGvqDcpHMRj7t3TG3PUGRxj1G3bu3jN5E1WEmP4130_assertion description "[Review/role of IL-10 in autoimmune diseases and its beneficial effects in cellular-based autoimmune diseases such as multiple sclerosis (MS) or its involvement in humoral-based autoimmune diseases such as systemic lupus erythematosus are discussed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119854.RASKijLGvqDcpHMRj7t3TG3PUGRxj1G3bu3jN5E1WEmP4130_provenance.
- NP119860.RAf95GBsIYnkfcGOFo-tmTMLuYRwtmc2DYV_njY4aqLEY130_assertion description "[IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119860.RAf95GBsIYnkfcGOFo-tmTMLuYRwtmc2DYV_njY4aqLEY130_provenance.
- NP119861.RAdnBM2MmzFay7Xdu_zJ6sna_0oKg1RfGotXvY8seD6zI130_assertion description "[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119861.RAdnBM2MmzFay7Xdu_zJ6sna_0oKg1RfGotXvY8seD6zI130_provenance.
- NP119862.RARFwOKbaPy9GihWh6osJwj6llOG12ecIe0P42YpDa5JE130_assertion description "[polymorphic variations of pro-inflammatory cytokines play an important role in susceptibility to multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119862.RARFwOKbaPy9GihWh6osJwj6llOG12ecIe0P42YpDa5JE130_provenance.
- NP119868.RAdbasiVbfSM_BlSLK00ym5X52n77ScxiHe3loZz-BWnY130_assertion description "[IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119868.RAdbasiVbfSM_BlSLK00ym5X52n77ScxiHe3loZz-BWnY130_provenance.
- NP119869.RAYkgQTUfVUc70ytp1lxeXN68vAgsr_76JrkaRMM1cwMk130_assertion description "[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119869.RAYkgQTUfVUc70ytp1lxeXN68vAgsr_76JrkaRMM1cwMk130_provenance.
- NP119870.RAYS8Kcio-jSwe9LmMU5a0vFily5nTiTu_xcAAs0YDn0k130_assertion description "[CD4 (+) TNFalpha (+) IL-2 (-) T cells are intrathecally upregulated in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119870.RAYS8Kcio-jSwe9LmMU5a0vFily5nTiTu_xcAAs0YDn0k130_provenance.
- NP119874.RAWQukLra3Zri_TAGT2D9yo-z-2ahRLXN326UxHdQMpUU130_assertion description "[both the spectrum of MBP found, as well as the MOGIgd epitopes recognized by peripheral blood T cells in multiple sclerosis, appear to be similar for childhood/juvenile-onset and adult-onset patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119874.RAWQukLra3Zri_TAGT2D9yo-z-2ahRLXN326UxHdQMpUU130_provenance.
- NP119875.RAZQFsU1yVzROFd5GfIN6epvh3eTUIb0e_JA7eLgHGvFw130_assertion description "[Demonstration of molecular mimicry between MOG and butyrophilin suggests that exposure to this common dietary antigen may influence the composition and function of the MOG-specific autoimmune repertoire during the course of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119875.RAZQFsU1yVzROFd5GfIN6epvh3eTUIb0e_JA7eLgHGvFw130_provenance.
- NP119877.RAZ2__7kfN9Sn_PGrvyDZIhqFiQ_RwyAk-VRViOAnF5Y4130_assertion description "[pathogenic antibody response to native MOG in a subgroup of multiple sclerosis patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119877.RAZ2__7kfN9Sn_PGrvyDZIhqFiQ_RwyAk-VRViOAnF5Y4130_provenance.
- NP119879.RAcpOWYX3rnvuCNLFugbWh__IWtm_yqyqm9KYtUAGOW_A130_assertion description "[MMP-9 in cortical plaques in multiple sclerosis patient is associated with loss of perineuronal nets ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119879.RAcpOWYX3rnvuCNLFugbWh__IWtm_yqyqm9KYtUAGOW_A130_provenance.
- NP119882.RAQkTiWdOYtR0VLzQqR6jzjFFwGr1VtaK6nOpuLxWiR0E130_assertion description "[The CTLA4 +49 A/G*G-CT60*G haplotype is associated with susceptibility to multiple sclerosis in Flanders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119882.RAQkTiWdOYtR0VLzQqR6jzjFFwGr1VtaK6nOpuLxWiR0E130_provenance.
- NP119886.RAVkGiNI3BbkY1GT8c-yZ1kddwbYANZu5usRS9gqSaJa0130_assertion description "[HIAP-1 and HIAP-2 mRNA levels were elevated in resting T cells while NAIP mRNA was increased in whole blood in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119886.RAVkGiNI3BbkY1GT8c-yZ1kddwbYANZu5usRS9gqSaJa0130_provenance.
- NP119889.RAUM41z40eDf_TG35CwrsP8ptdA5vUGpQaXu8_pluc0EM130_assertion description "[Patients with multiple sclerosis and allelic polymorphism of APOE epsilon 4 have a significantly higher progression index of disability and a worse ranked multiple sclerosis severity score than their non-epsilon 4 counterparts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119889.RAUM41z40eDf_TG35CwrsP8ptdA5vUGpQaXu8_pluc0EM130_provenance.
- NP119890.RAQ59ni8XW3rNTIEgxnvpGoUV-NNW3hYTVtCEJxMjdxX8130_assertion description "[The Apo epsilon4 allele seems to predispose carriers with multiple sclerosis to a faster progression of disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119890.RAQ59ni8XW3rNTIEgxnvpGoUV-NNW3hYTVtCEJxMjdxX8130_provenance.
- NP119898.RAbksuQq9JWjBcM54zKLS1_wDdtpPnj_c6KO12rcNdWPY130_assertion description "[disease onset and progression to disability may be prolonged in multiple sclerosis carriers of CCR5-Delta32 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119898.RAbksuQq9JWjBcM54zKLS1_wDdtpPnj_c6KO12rcNdWPY130_provenance.
- NP119906.RAZ9FCz-We2Su0ziSqVEJZ8IegGwdnQ_jyE1vritJn8U4130_assertion description "[Point mutation occurred in mtDNA might be involved in pathogenesis of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119906.RAZ9FCz-We2Su0ziSqVEJZ8IegGwdnQ_jyE1vritJn8U4130_provenance.
- NP119910.RAYAtLTqYHlyUAcHAQBoTFJWpuZfx2hvIb8szPzZgJ-IM130_assertion description "[Specific Kv1.3 blockers may be beneficial in autoimmune diseases such as multiple sclerosis in which effector memory T cells are found in the target organ ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119910.RAYAtLTqYHlyUAcHAQBoTFJWpuZfx2hvIb8szPzZgJ-IM130_provenance.
- NP119911.RAVkSVyKvCP2TuxDRhwU4t7u35zJza3Y1pAknLDHti0js130_assertion description "[Our findings highlight myelin oligodendrocyte glycoprotein splicing as a factor that could be critical to the phenotypic expression of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119911.RAVkSVyKvCP2TuxDRhwU4t7u35zJza3Y1pAknLDHti0js130_provenance.
- NP119915.RAbo16phvRMcgdaXULESgYcjZIStTa80PSA4jpqh0eQco130_assertion description "[expansion of CD5- B cells in multiple sclerosis correlates with CD80 (B7-1) expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119915.RAbo16phvRMcgdaXULESgYcjZIStTa80PSA4jpqh0eQco130_provenance.
- NP119916.RAYywtGLR8O1pdkRtaHrkhR0yaVuda34M7il1TsxY3LR0130_assertion description "[IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119916.RAYywtGLR8O1pdkRtaHrkhR0yaVuda34M7il1TsxY3LR0130_provenance.
- NP119918.RAUieqRRcQTzoRLn-Gq8DQ9bhKY1mvot_YTK-tLqRi3OQ130_assertion description "[Patients with the remitting/relapsing form of multiple sclerosis have strikingly reduced numbers of CD39 (+) Treg cells in the blood ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119918.RAUieqRRcQTzoRLn-Gq8DQ9bhKY1mvot_YTK-tLqRi3OQ130_provenance.
- NP119921.RAalZiYlulrMOA1VOrSFIKb6w6jrqozDIIszJv6SfajdM130_assertion description "[there is an enrichment of both IL-17+CD4+ and CD8+ T cells in active multiple sclerosis lesions ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119921.RAalZiYlulrMOA1VOrSFIKb6w6jrqozDIIszJv6SfajdM130_provenance.
- NP119930.RAcmhys5yCK0eKlUeJbDP-J2LLPvDd1oQEjTMvDzbafV4130_assertion description "[soluble proteins of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and IL-6 receptor subunit gp80 (sIL-6R gp80), as markers of multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119930.RAcmhys5yCK0eKlUeJbDP-J2LLPvDd1oQEjTMvDzbafV4130_provenance.
- NP119932.RAaaXZjim6zKKLAQAJkyjbDnx2rsI-phsVElW6N75cU-Y130_assertion description "[A sequence variation in the MOG gene is involved in multiple sclerosis susceptibility in Italy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119932.RAaaXZjim6zKKLAQAJkyjbDnx2rsI-phsVElW6N75cU-Y130_provenance.
- NP119936.RAVJT5ofb6LH172kG6gVOq-P0ZHjpAvHJSIbmFtpJ3YhI130_assertion description "[The amount of peptidyl arginine deiminase type II enzyme and citrullinated myelin basic protein was increased in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119936.RAVJT5ofb6LH172kG6gVOq-P0ZHjpAvHJSIbmFtpJ3YhI130_provenance.
- NP119939.RAbSJXUNE_rIbCoXe_CJiObu2ZphFwHWIsB2K-IoR36uo130_assertion description "[Gene expression incresed in multiple sclerosis patients treated with interferon-beta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119939.RAbSJXUNE_rIbCoXe_CJiObu2ZphFwHWIsB2K-IoR36uo130_provenance.
- NP119942.RATZMQG7HptyF5JtTpEb296qEl5dwujfrHMk3kOID-zZw130_assertion description "[The association between MICA transmembrane polymorphisms and multiple sclerosis progression was investigated ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119942.RATZMQG7HptyF5JtTpEb296qEl5dwujfrHMk3kOID-zZw130_provenance.
- NP119946.RAR7PNytSxJUlOgt_qcDwBBiY3eoxpI17uSdC1hKBJez4130_assertion description "[C270T and G196A BDNF polymorphisms may affect susceptibility to and onset of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119946.RAR7PNytSxJUlOgt_qcDwBBiY3eoxpI17uSdC1hKBJez4130_provenance.
- NP119947.RAT0mjjHFdi1oIcUPqpEOr15ECZ95pIIwodUpOSBKz_JU130_assertion description "[TPI and GAPDH may be candidate Ags for an autoimmune response to neurons and axons in multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119947.RAT0mjjHFdi1oIcUPqpEOr15ECZ95pIIwodUpOSBKz_JU130_provenance.
- NP119952.RAel6NerMEM2Of08Y1Z2-DEHQJeyXYaPy-AyKmh5w_PMQ130_assertion description "[myelin basic protein charge isomer, component-8, was more susceptible to stromelysin-1 cleavage than myelin basic protein component-1; increased susceptibility of component-8 to proteolytic digestion may play a role in pathogenesis of multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119952.RAel6NerMEM2Of08Y1Z2-DEHQJeyXYaPy-AyKmh5w_PMQ130_provenance.
- NP119957.RAdpAufRMfy9UXhiTNBznUKE-rkM7A33UcGAIuR3j8zj0130_assertion description "[Association of MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119957.RAdpAufRMfy9UXhiTNBznUKE-rkM7A33UcGAIuR3j8zj0130_provenance.
- NP119960.RAf2Sft7-1EtZ_7h5uRdMKWZtNwhtdvYUfqMRHd4KA8CU130_assertion description "[the ternary complex of NgR/TROY/LINGO-1 expressed on astrocytes, macrophages/microglia and neurones, by interacting with Nogo-A on oligodendrocytes, might modulate glial-neuronal interactions in demyelinating lesions of multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119960.RAf2Sft7-1EtZ_7h5uRdMKWZtNwhtdvYUfqMRHd4KA8CU130_provenance.
- NP119976.RAcLe6BfBnZsn-U1Fh2gJ_eoihTOOg3j-Dan5WGjXrU1o130_assertion description "[TCRVbeta5-2 spectratype expansion is associated with the development of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119976.RAcLe6BfBnZsn-U1Fh2gJ_eoihTOOg3j-Dan5WGjXrU1o130_provenance.
- NP119980.RARqr6Im8lLMnB8dQN0wwj9V0hR54i2HkaGy_hhbeeH1k130_assertion description "[Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119980.RARqr6Im8lLMnB8dQN0wwj9V0hR54i2HkaGy_hhbeeH1k130_provenance.
- NP119981.RAV81KWW3901Oe54fZ-m_E5zwwmkCsVMYNV4NTbZh5Q38130_assertion description "[Both in multiple sclerosis and other inflammatory neurological diseases, tau protein levels in the cerebrospinal fluid (csf) are significantly higher than in csf samples from non-inflammatory neurological diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119981.RAV81KWW3901Oe54fZ-m_E5zwwmkCsVMYNV4NTbZh5Q38130_provenance.
- NP119985.RAel8TCHGgZB0NHjDEDK_inftoVJLVeZm4m4o2MoO9a_s130_assertion description "[Mononuclear leukocytes of multiple sclerosis patients have a deficiency in SHP-1 and increased inflammatory gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119985.RAel8TCHGgZB0NHjDEDK_inftoVJLVeZm4m4o2MoO9a_s130_provenance.
- NP119987.RAf4e5Q--7wyN4KYoVNkWvUQ0UB0kyS_i28-d2D1vUNWI130_assertion description "[the PAFR gene missense mutation has a relation to the susceptibility for multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119987.RAf4e5Q--7wyN4KYoVNkWvUQ0UB0kyS_i28-d2D1vUNWI130_provenance.
- NP119995.RARgFiq16sxCW1_T1SPAGGdMFWH1FLfZVJKn41dWR_aew130_assertion description "[detected a significant positive correlation between TNF-alpha (r = 0.55) and interferon-gamma (r = 0.54) mRNA expression and the Beck Depression Inventory sum scores during an acute attack in multiple sclerosis patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119995.RARgFiq16sxCW1_T1SPAGGdMFWH1FLfZVJKn41dWR_aew130_provenance.
- NP119996.RAazgkwG82ejbELkUDW1-mJvJav17kx9vMTYwBM4QEfCo130_assertion description "[expressed in multiple sclerosis brain lesions ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119996.RAazgkwG82ejbELkUDW1-mJvJav17kx9vMTYwBM4QEfCo130_provenance.
- NP119999.RAff5YTCnV9sNwexmo4-_bD7xdZeL-e4JM_-OUkcHORmw130_assertion description "[data show that genetic variants in the IRF-1 and Stat1 genes of the IFN pathway are associated with multiple sclerosis and hepatitis c virus infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP119999.RAff5YTCnV9sNwexmo4-_bD7xdZeL-e4JM_-OUkcHORmw130_provenance.
- NP120004.RAXVX1-KNaKZmZcBip45dPvd59_zm4PVQYGIDNbKw1qAQ130_assertion description "[multiple sclerosis may function in part by restoring TIM-3 immunoregulation of T cell function ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120004.RAXVX1-KNaKZmZcBip45dPvd59_zm4PVQYGIDNbKw1qAQ130_provenance.
- NP120006.RAehHtF-2jXOUJba_jQjgecp5vwyBBg77bReNzSmlrZrw130_assertion description "[The results of this study indicate a significant reduction in the number of PV interneurons within layer 2 of the multiple sclerosis primary motor cortex ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120006.RAehHtF-2jXOUJba_jQjgecp5vwyBBg77bReNzSmlrZrw130_provenance.
- NP120008.RAXpbi9_zcVGhXWRxhYvx2Afm7MjqlSAfWDydCfsLNLxU130_assertion description "[Ultraviolet radiation (UVR) may contribute to multiple sclerosis (MS) outcome by a mechanism involving vitamin D and the vitamin D receptor (VDR) ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120008.RAXpbi9_zcVGhXWRxhYvx2Afm7MjqlSAfWDydCfsLNLxU130_provenance.
- NP120010.RAbSbpnJuD6Baajs7ceXlZhOMBmqjXf9mQ8fjp98bQU_U130_assertion description "[Results suggest that allelic variation in the NRAMP1 promoter may contribute to multiple sclerosis susceptibility in the Sardinian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120010.RAbSbpnJuD6Baajs7ceXlZhOMBmqjXf9mQ8fjp98bQU_U130_provenance.
- NP120011.RAXeigT-GDhZFwx2yOmw4z1Do_0oYT9rvteoiJqhjPs2E130_assertion description "[CX3CR1 is downregulated in patients with multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120011.RAXeigT-GDhZFwx2yOmw4z1Do_0oYT9rvteoiJqhjPs2E130_provenance.
- NP120012.RAaM8vtyhw6b4SVjDvgv03gOWufuuWu6p8vAiaRzGJrIk130_assertion description "[enhanced expression of glutamate transporters in multiple sclerosis constitutes a regulatory response of glial cells to toxic levels of glutamate in the CNS during inflammation and neurodegeneration ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120012.RAaM8vtyhw6b4SVjDvgv03gOWufuuWu6p8vAiaRzGJrIk130_provenance.
- NP120015.RAYlHT5uLTSu4vLDvyKdLV8yX0fWqxPmA4_CAta_qkhNs130_assertion description "[fluctuations in CSF sHLA-G and sFas levels observed when MRI disease activity resolved suggest that sHLA-G could play an immunomodulatory role in multiple sclerosis through Fas/FasL-mediated mechanisms ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120015.RAYlHT5uLTSu4vLDvyKdLV8yX0fWqxPmA4_CAta_qkhNs130_provenance.
- NP120021.RAeJaHjYBDY02Pi5-0EhZR2PW5tgEx6vpJ5GeFd2LRqho130_assertion description "[In patient with multiple sclerosis all HLA-DRB1 risk alleles were more common in Malta, whereas HLA-DRB1*11 was slightly less common.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120021.RAeJaHjYBDY02Pi5-0EhZR2PW5tgEx6vpJ5GeFd2LRqho130_provenance.
- NP120022.RAeGI0RCXEaqUAuxNwMEnzojdXSyvcC3pyQ8AdJdQhoPU130_assertion description "[HLA DRB1*15 was present in 70% of multiple sclerosis affected individuals; the transmission disequilibrium test showed a significant excess in transmission of DRB1*15 alleles to affected individuals ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120022.RAeGI0RCXEaqUAuxNwMEnzojdXSyvcC3pyQ8AdJdQhoPU130_provenance.
- NP120025.RAf4PYYesTikII6UAcaqkuKZOCAEB34ibsWs_1FnjWTv8130_assertion description "[Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120025.RAf4PYYesTikII6UAcaqkuKZOCAEB34ibsWs_1FnjWTv8130_provenance.
- NP120027.RAWbLX4Y6S5j8Eexippfem5s1FuS8B5Vj2AHCT1pmWtxY130_assertion description "[Parental transmission of HLA-DRB1*15 in multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120027.RAWbLX4Y6S5j8Eexippfem5s1FuS8B5Vj2AHCT1pmWtxY130_provenance.
- NP120032.RARpTr6Cm-tb0jbiRXu5DDVwTXkCX0f3qjI-9iVeOozoQ130_assertion description "[Heterogeneous phenotypes occur in both Brazilian ethnic groups: African-Brazilian and white Brazilian in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120032.RARpTr6Cm-tb0jbiRXu5DDVwTXkCX0f3qjI-9iVeOozoQ130_provenance.
- NP120040.RAV9HvVA7r0SgKQP5dYHzQbLmqGOKIY8RUZuo6NalioGU130_assertion description "[Presence of anti-AQP4 antibodies correlates with clinical severity and poor prognosis in opticospinal multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120040.RAV9HvVA7r0SgKQP5dYHzQbLmqGOKIY8RUZuo6NalioGU130_provenance.
- NP120048.RAUzWKmATc_gEm0BRsVYX0086-jClpd2SdD-iCev1VG6I130_assertion description "[UCP2 promoter polymorphism may contribute to multiple sclerosis susceptibility by regulating the level of UCP2 protein in the central nervous and/or the immune systems.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120048.RAUzWKmATc_gEm0BRsVYX0086-jClpd2SdD-iCev1VG6I130_provenance.
- NP120049.RAUrXpJOCzZcVRxCxEZ5uw0FJ3L0OQn11nyyboPzjJhjA130_assertion description "[Link between UCP2 single-nucleotide polymorphism and multiple sclerosis and a slight relation with muscle mitochondrial haplotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120049.RAUrXpJOCzZcVRxCxEZ5uw0FJ3L0OQn11nyyboPzjJhjA130_provenance.
- NP120050.RAW8atxlTMSsZbfCyQx7hE6BCipYkRN_Kb0fGIoWo24p4130_assertion description "[IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120050.RAW8atxlTMSsZbfCyQx7hE6BCipYkRN_Kb0fGIoWo24p4130_provenance.
- NP120051.RAbfwwgzALbDacjpNd2nLB8Qr2hA0DrahiVxjnLXHtDCw130_assertion description "[Intrathecal production and fluctuations in CSF and serum concentrations of HLA-I were reciprocal in multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120051.RAbfwwgzALbDacjpNd2nLB8Qr2hA0DrahiVxjnLXHtDCw130_provenance.
- NP120053.RAaWXHCa-1ncB0ANi629ikg8t2syFTaAnQ-CN6rPg2FX8130_assertion description "[Heterogeneous phenotypes occur in both Brazilian ethnic group: African-Brazilian and white Brazilian in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120053.RAaWXHCa-1ncB0ANi629ikg8t2syFTaAnQ-CN6rPg2FX8130_provenance.
- NP120054.RAcv_5dGM-iYHTCKyJ1D6jj_xXdINW5N19f47uYRmUOvM130_assertion description "[Intrathecal production and fluctuations in CSF and serum concentrations of sHLA-I were reciprocal in multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120054.RAcv_5dGM-iYHTCKyJ1D6jj_xXdINW5N19f47uYRmUOvM130_provenance.
- NP120058.RAWM_a4Q4oSWLAOup_idDiKYAQ91_CQ2Edv_NAA9_7Ncc130_assertion description "[Longitudinal data indicate that FasL mRNA increases in peripheral blood mononuclear cells of multiple sclerosis (MS) patients, especially during the secondary progressive course, and is downregulated during clinical activity in relapsing remitting MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120058.RAWM_a4Q4oSWLAOup_idDiKYAQ91_CQ2Edv_NAA9_7Ncc130_provenance.
- NP120060.RAYeIDOK9oTQ3DFW5q5A5rDE5_5h9f2svy6hqIIR8G3sM130_assertion description "[An abnormal type-1 T helper (Th1) cell bias exists related to IL-23-expressing dendritic cells from multiple sclerosis (MS) patients, which may play an important role in the pathogenesis of human autoimmune diseases such as MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120060.RAYeIDOK9oTQ3DFW5q5A5rDE5_5h9f2svy6hqIIR8G3sM130_provenance.
- NP120061.RAZG5IJVB6ZUxAgDYeaYm8Ftm640BYV8vMVzWfUWIX4sQ130_assertion description "[an important involvement of alpha2M in regulation of increased proteolytic activity occurring in multiple sclerosis disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120061.RAZG5IJVB6ZUxAgDYeaYm8Ftm640BYV8vMVzWfUWIX4sQ130_provenance.
- NP120067.RASLyI7A0M3w6USZroPYGoxJlfcPwTLrhN3X1L2RAuZA4130_assertion description "[Almost all multiple sclerosis patients had cerebrospinal fluid IgG directed to isoforms of one of the oligodendroglial molecules, transketolase, 2 ', 3'-cyclic-nucleotide 3'-phosphodiesterase type I, collapsin response mediator protein 2, and tubulin beta4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120067.RASLyI7A0M3w6USZroPYGoxJlfcPwTLrhN3X1L2RAuZA4130_provenance.
- NP120070.RAST-LwNhzW2dXCnkEboJOe6nJJ95LiwiEVRm8AiaGPoY130_assertion description "[Elevated expression of CCR5 by myeloid (CD11c+) blood dendritic cells in multiple sclerosis and acute optic neuritis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120070.RAST-LwNhzW2dXCnkEboJOe6nJJ95LiwiEVRm8AiaGPoY130_provenance.
- NP120071.RAW1nZybNf3MeUlNvxKwfYiudzaPp3XfuEZgB1uh55qWo130_assertion description "[Polymorphism in this enzyme and glyoxalase I increase susceptibility to multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120071.RAW1nZybNf3MeUlNvxKwfYiudzaPp3XfuEZgB1uh55qWo130_provenance.
- NP120072.RAerYk6UddL9yH9wfWz7PTROnBOMCRynY5S44wVmkYlvU130_assertion description "[XIAP and HIAP-1 in myelin lesions were co-localized with microglia and T cells in multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120072.RAerYk6UddL9yH9wfWz7PTROnBOMCRynY5S44wVmkYlvU130_provenance.
- NP120086.RAXlq2LVizSGRy2gXlEAgwU7xMKXi8VY3HH3A7jMGLblg130_assertion description "[Anti-P-selectin glycoprotein ligand-1 (PSGL-1) antibodies dramatically block the recruitment of CD8+ cells in brain vessels of patients with multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120086.RAXlq2LVizSGRy2gXlEAgwU7xMKXi8VY3HH3A7jMGLblg130_provenance.
- NP120087.RAWRDKXeJ2wW4MQMAJglzzx4GjoJFxEABluyiKIYAgst4130_assertion description "[Beta-tryptase activates peripheral blood mononuclear cells isolated from healthy donors as well as multiple sclerosis (MS) patients, inducing release of TNF-alpha, IL-6, and IL-1 beta, and is most probably an important mediator of inflammation in MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120087.RAWRDKXeJ2wW4MQMAJglzzx4GjoJFxEABluyiKIYAgst4130_provenance.
- NP120088.RAVncz-IokxLOJ1ueqSOW7bVo3BCg4lJFqvSc4BgQVbWY130_assertion description "[Association between the phenylethanolamine N-methyltransferase gene and multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120088.RAVncz-IokxLOJ1ueqSOW7bVo3BCg4lJFqvSc4BgQVbWY130_provenance.
- NP120089.RAZtTHTceoEjFCQ5hYGH8YCP1b_vtZNzRimj4NGsk5gB0130_assertion description "[The TGFB1 T+869C (Leu10Pro) gene polymorphism is associated with multiple sclerosis susceptibility, especially in males.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120089.RAZtTHTceoEjFCQ5hYGH8YCP1b_vtZNzRimj4NGsk5gB0130_provenance.
- NP120107.RAY6qUUPUeLbO6Fw-FDxM4d5Dfk6UpbBl4ElyzBvmlrw8130_assertion description "[Administration of recombinant CRYAB ameliorated EAE; thus, the immune response against a negative regulator of inflammation, CRYAB, in multiple sclerosis, would exacerbate inflammation and demyelination.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120107.RAY6qUUPUeLbO6Fw-FDxM4d5Dfk6UpbBl4ElyzBvmlrw8130_provenance.
- NP120109.RAUqXTfcDb873kei7t1L2CgLtGl3nKn79AHkwIHqC-V-I130_assertion description "[A null mutation in this protein was evaluated for a relationship to disease susceptibility and disease severity in patients with multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120109.RAUqXTfcDb873kei7t1L2CgLtGl3nKn79AHkwIHqC-V-I130_provenance.
- NP120115.RASQq44qRLYYrXNKwT1PNwmjYIl83cZ19jHy4uE075K4w130_assertion description "[Altered patterns of CXCL12 expression at the BBB were specifically associated with multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120115.RASQq44qRLYYrXNKwT1PNwmjYIl83cZ19jHy4uE075K4w130_provenance.
- NP120119.RAendGuarJka-3y9suavoyMLf9enhFfWNnShOMCBwMrJU130_assertion description "[We report the increased expression of stathmin, a developmentally regulated tubulin-binding protein, in the brains of patients with multiple sclerosis (MS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120119.RAendGuarJka-3y9suavoyMLf9enhFfWNnShOMCBwMrJU130_provenance.
- NP120125.RAV26Gs68gGqoAdLqyyZLlGHr6Ak4zr8DJYpJuFWKZW5c130_assertion description "[Polymorphisms in human platelet alloantigen (HPA) -1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa) and HPA-5 (GPIa/IIa) were found to be associated with the symptoms and recurrence of ischemic stroke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120125.RAV26Gs68gGqoAdLqyyZLlGHr6Ak4zr8DJYpJuFWKZW5c130_provenance.
- NP120128.RAVYpWVwYhYOIFcGk4H2O-GDhrkpH5bFLKyaRKqfwg6GM130_assertion description "[Increased serum and urine IL-18 levels were observed during relapse of idiopathic nephrotic syndrome ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120128.RAVYpWVwYhYOIFcGk4H2O-GDhrkpH5bFLKyaRKqfwg6GM130_provenance.
- NP120136.RAQ3Uwj6M4dbKSOxBLZWfEH6pCYAMNjNZhzszEU_bMqis130_assertion description "[Patients who had a combined BM relapse had lower IL-8 and CXCR4 expression than those who had an isolated BM relapse om chldhood acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120136.RAQ3Uwj6M4dbKSOxBLZWfEH6pCYAMNjNZhzszEU_bMqis130_provenance.
- NP120140.RAT145vKMAprTiYFb420e2S1NX4DTdD_-NMWVMEembUc0130_assertion description "[high levels of plasma MMP-9 activity is associated with evidence of recurrence in breast cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120140.RAT145vKMAprTiYFb420e2S1NX4DTdD_-NMWVMEembUc0130_provenance.
- NP120143.RAaDTYqdB2GfyJCB9oGD1ede-ec7Lg2VCoRCGiSF6c92M130_assertion description "[aberrant gene regulation by NF-kappaB on T-cell transcriptome may have a role in relapse of multiple sclerosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120143.RAaDTYqdB2GfyJCB9oGD1ede-ec7Lg2VCoRCGiSF6c92M130_provenance.
- NP120150.RAXiowbCmlFy4mmyXQ25F5gxGiG1ovN_SLjL_C590MAA4130_assertion description "[Elevated circulating endothelial progenitor marker CD133 messenger RNA levels are associated with colon cancer recurrence ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120150.RAXiowbCmlFy4mmyXQ25F5gxGiG1ovN_SLjL_C590MAA4130_provenance.
- NP120151.RAakn-cf6aypNxGZ-woSJYfVd27ZOVyDW1EJdsa3eViVw130_assertion description "[Overexpression of CUB-domain containing protein 1 is associated with metastasis and recurrence in renal cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120151.RAakn-cf6aypNxGZ-woSJYfVd27ZOVyDW1EJdsa3eViVw130_provenance.
- NP120160.RAW7XAw0piPiUWg2X9ikm92EjzFyGhs4nm4xDH-pwYnHQ130_assertion description "[High levels of galectin 7 expression were associated with rapid recurrence rates in hypopharyngeal cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120160.RAW7XAw0piPiUWg2X9ikm92EjzFyGhs4nm4xDH-pwYnHQ130_provenance.
- NP120161.RAS09MIIOoq-IHT4q2AKlsPINKWyENZORpa3PHU8Yy1bc130_assertion description "[High C-erbB-2 expression is associated with recurrence in breast cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP120161.RAS09MIIOoq-IHT4q2AKlsPINKWyENZORpa3PHU8Yy1bc130_provenance.