Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP121276.RATrUMqj7shrWizmSLnCKlrvWbEvX4KWeG5V4uJxnle_M130_assertion description "[a mutant allele of MRE11 found in a colon cancer cell line sensitizes cells to agents causing replication fork stress/mutant Mre11 weakly interacts with Rad50 relative to wild type and shows little affinity for Nbs1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121276.RATrUMqj7shrWizmSLnCKlrvWbEvX4KWeG5V4uJxnle_M130_provenance.
- NP121277.RAXQhZ4DGsRKPtqjld2sit0-Uhq8VnkFUr-SMwq16Keuk130_assertion description "[LPA acts as a potent stimulator of colon cancer progression, although the binding to LPA1 and LPA2 induces slightly different responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121277.RAXQhZ4DGsRKPtqjld2sit0-Uhq8VnkFUr-SMwq16Keuk130_provenance.
- NP121285.RAaYnMkA81XzQHp4mWS0I38gFg7ic-JfGgB_jWmQHjIN0130_assertion description "[Germline mutation of BMPR1A in a family with juvenile polyposis and colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121285.RAaYnMkA81XzQHp4mWS0I38gFg7ic-JfGgB_jWmQHjIN0130_provenance.
- NP121289.RAYjOKlQMGQS69TB-SYU4POf8YgFovkVu3wY1HXu0u4g8130_assertion description "[UGT1A1-3279 GG/TG intermediate/low activity genotypes were associated with an increased risk of colon cancer (odds ratio (OR) = 1.5, 95% confidence interval (CI) = 1.1-2.0) in Caucasians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121289.RAYjOKlQMGQS69TB-SYU4POf8YgFovkVu3wY1HXu0u4g8130_provenance.
- NP121293.RARbsPAKuCV5F9yot442ifbneNDZCtJGV00YtjnvGALw0130_assertion description "[PSB7, PRDX1, and SRP9 up-regulation as candidate biomarkers of colon cancer is discovered ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121293.RARbsPAKuCV5F9yot442ifbneNDZCtJGV00YtjnvGALw0130_provenance.
- NP121298.RAeRzaubCeDihtLuvN0ayn6kF6U5xKlW9Fb2J9iT-QXUY130_assertion description "[our results support the feasibility of using adenovirus-mediated RNA interference therapy targeting Bcl-XL against colon cancers and warrant further studies of its safety and efficacy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121298.RAeRzaubCeDihtLuvN0ayn6kF6U5xKlW9Fb2J9iT-QXUY130_provenance.
- NP121300.RASWqaZlq_rLFFvpzDvJgGysRUoeEQc7eUgWQ2kj5S0b4130_assertion description "[Increased expression of HSP90 Heat-Shock Proteins is associated with colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121300.RASWqaZlq_rLFFvpzDvJgGysRUoeEQc7eUgWQ2kj5S0b4130_provenance.
- NP121301.RAaxyaf97Nrj8ihOf9Qe8gdbv_wY7xcXeizak_3NRsYIg130_assertion description "[Expressed in colon cancer cells [NIP71]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121301.RAaxyaf97Nrj8ihOf9Qe8gdbv_wY7xcXeizak_3NRsYIg130_provenance.
- NP121305.RAViKtBDAYR86stWzF59NlndJbSy8Vtf-dnGO5zOy9R9s130_assertion description "[Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121305.RAViKtBDAYR86stWzF59NlndJbSy8Vtf-dnGO5zOy9R9s130_provenance.
- NP121307.RAQCA4fLe_lwjDnk8BeyPzKFNr4vTTR-uPQ9NW9_vBjuU130_assertion description "[AIF maintains the transformed state of colon cancer cells through its NADH oxidase activity, by mechanisms that involve complex I function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121307.RAQCA4fLe_lwjDnk8BeyPzKFNr4vTTR-uPQ9NW9_vBjuU130_provenance.
- NP121310.RAcUG-xpf81QUDzzlg5cN_bAdQJsNSn4gsybASuTJZnj0130_assertion description "[The results indicate that epigenetic gene silencing of SPARC is frequent in colon cancers, and that inactivation of SPARC is related to rapid progression of colon cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121310.RAcUG-xpf81QUDzzlg5cN_bAdQJsNSn4gsybASuTJZnj0130_provenance.
- NP121312.RASxlxyJGX63gFHWVRP0OfcnfbyffC_Rm0VyNJvpYG-LY130_assertion description "[role for Sp1 in the regulation of expression of the angiogenic factor TP in colon cancer WiDr cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121312.RASxlxyJGX63gFHWVRP0OfcnfbyffC_Rm0VyNJvpYG-LY130_provenance.
- NP121324.RAUZUDhOgMw4trw7SUkbZrJfTaLBclMR32YLRmTN0h-vA130_assertion description "[Results suggest that the VEGF 936C > T polymorphism might be a genetic determinant for colon cancer, at least in Koreans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121324.RAUZUDhOgMw4trw7SUkbZrJfTaLBclMR32YLRmTN0h-vA130_provenance.
- NP121333.RAVLDUNsvGxQhj3T24BkUfiY0eC0ex561-9FSNd0Et-Sc130_assertion description "[FAK and Src are important survival factors, playing a role in protecting colon cancer cell lines from Adenovirus-containing FAK-CD (Ad-FAK-CD) -induced apoptosis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121333.RAVLDUNsvGxQhj3T24BkUfiY0eC0ex561-9FSNd0Et-Sc130_provenance.
- NP121343.RARWITeQ3nBvjwuzHai-wKogRi-xTOB18omq87pFpYHpk130_assertion description "[These results suggested that the combination of 5-FU and genistein exert a novel chemotherapeutic effect in colon cancers, and AMPK may be a regulatory molecule of COX-2 expression, further implying its involvement in cytotoxicity caused by genistein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121343.RARWITeQ3nBvjwuzHai-wKogRi-xTOB18omq87pFpYHpk130_provenance.
- NP121344.RAVL90py-9fB3Jgpaw3gJFosc-gEl0g2MJvw2l_EjUt-g130_assertion description "[COX-2 and beta-Catenin may have roles in regulating intracellular Survivin levels in mouse and human colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121344.RAVL90py-9fB3Jgpaw3gJFosc-gEl0g2MJvw2l_EjUt-g130_provenance.
- NP121347.RAWwwhdaBtQAuuI0Kj_8MyCJhA3Rdm8GoYES435QlYBQk130_assertion description "[Pontin52/TIP49a promotes COX-2 expression in tissue culture and is overexpressed in colon cancer tissue, co-localizing with COX-2 expression in transformed tissue, relative to paired normal tissue ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121347.RAWwwhdaBtQAuuI0Kj_8MyCJhA3Rdm8GoYES435QlYBQk130_provenance.
- NP121363.RAaOpNliJykK6GSMJTDboQv8aJ3dTA5RAIypG4E1Divuw130_assertion description "[Report shows that adenosine downregulation of DPPIV from the surface of colon cancer cells occurs independently of the classic receptors, and is mediated by a novel cell-surface mechanism that induces an increase in protein tyrosine phosphatase activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121363.RAaOpNliJykK6GSMJTDboQv8aJ3dTA5RAIypG4E1Divuw130_provenance.
- NP121366.RAZPOaAXCdjFoYdTVrykeuqmopTtU-_JbFUKiX-rwkdhw130_assertion description "[Down-regulation of scrib is associated with colon cancer progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121366.RAZPOaAXCdjFoYdTVrykeuqmopTtU-_JbFUKiX-rwkdhw130_provenance.
- NP121374.RAVHi8ZjKE_k6hnUHDFYqOi2WnxqLfyKntskiruoiy4UU130_assertion description "[Down-regulation of DLG1 is associated with colon cancer progression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121374.RAVHi8ZjKE_k6hnUHDFYqOi2WnxqLfyKntskiruoiy4UU130_provenance.
- NP121387.RAfxOiAAHr7xNBlCJPbPl8RVHNeUlmDnMD4zCk9LYkuPg130_assertion description "[Study isolated a novel human gene, to be called as CANu1, by the large-scale genome-wide association analysis to screen specific Single nucleotide polymorphisms in colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121387.RAfxOiAAHr7xNBlCJPbPl8RVHNeUlmDnMD4zCk9LYkuPg130_provenance.
- NP121388.RAZTANjRF41K9TaEWRLBfCNqBnnkYuDpn_Tf73ccPayaw130_assertion description "[demonstration that IL8, DES and ENO1 act as the central elements in colon cancer susceptibility, and protein biosynthesis and the ribosome-associated function categories largely account for the colon cancer tumuorigenesis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121388.RAZTANjRF41K9TaEWRLBfCNqBnnkYuDpn_Tf73ccPayaw130_provenance.
- NP121392.RAf_12VvZbHi1_rwNmd1CYvUgbQANENkLWMXooi9hHV-8130_assertion description "[Gadd45a-deficient human colon cancer cells exhibited slow base excision repair after treatment with methyl methanesulfonate, a pure base-damaging agent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121392.RAf_12VvZbHi1_rwNmd1CYvUgbQANENkLWMXooi9hHV-8130_provenance.
- NP121394.RAZ95pnbk-ba1r_mnfh_6YUNu_jaJrRsYGdw3aL-Ra2Ts130_assertion description "[a dramatic alteration in the distribution of histamine receptors in colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121394.RAZ95pnbk-ba1r_mnfh_6YUNu_jaJrRsYGdw3aL-Ra2Ts130_provenance.
- NP121400.RAfDEn7V7j00fdRM-Ml1FIYoyFk7Rl6cbTTJRgticeVVY130_assertion description "[Genetic variation at the VDR locus, in particular Cdx-2 and FokI single-nucleotide polymorphism is associated with colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121400.RAfDEn7V7j00fdRM-Ml1FIYoyFk7Rl6cbTTJRgticeVVY130_provenance.
- NP121402.RAaHnVESEIkIXWFOwKLcXTTm9rmcOf7ChV9ncCOVLQ1NA130_assertion description "[15-PGDH transcript and protein are both highly expressed by normal colonic epithelia but are nearly undetectable in colon cancers ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121402.RAaHnVESEIkIXWFOwKLcXTTm9rmcOf7ChV9ncCOVLQ1NA130_provenance.
- NP121403.RAU_QcZdellQENeWY5YhZkWCDxVZiS1wEuwqQDWo0HSm8130_assertion description "[the expression ratio of Map7/B2M may serve as a valuable prognostic marker in patients with Stage II colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121403.RAU_QcZdellQENeWY5YhZkWCDxVZiS1wEuwqQDWo0HSm8130_provenance.
- NP121404.RAeICnTa5dcBTF-kWDmu5H336giNEpUK-s5_G2-MECWqs130_assertion description "[Downregulated expression of the candidate tumour suppressor gene SASH1 is associated with colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121404.RAeICnTa5dcBTF-kWDmu5H336giNEpUK-s5_G2-MECWqs130_provenance.
- NP121408.RAXlg8GNDm1rLKmotBdjWAPh5BzIhqajF8QvZ4V_Ou7Jk130_assertion description "[This study suggests that (a) PTP1B can act as an important activator of Src in colon cancer cells via dephosphorylation at Y530 of Src and (b) elevated levels of PTP1B can increase tumorigenicity of colon cancer cells by activating Src.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121408.RAXlg8GNDm1rLKmotBdjWAPh5BzIhqajF8QvZ4V_Ou7Jk130_provenance.
- NP121410.RAQo7jfDUjVODV6g3JNTVVNVCXSYsWhzU8mZLl3j6bjwE130_assertion description "[may play a role in colon cancer invasion and metastasis by increasing cell proliferation and adhesion to the ECM via upregulation of proinvasive integrin expression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121410.RAQo7jfDUjVODV6g3JNTVVNVCXSYsWhzU8mZLl3j6bjwE130_provenance.
- NP121411.RARToz3D_QFpORjRlgK8P9RoKHvR70xAmq36lDdmTAdCg130_assertion description "[The PCox-1a RNA molecules are expressed by human intestinal epithelial cells in a controlled manner, are most likely not translated and play a regulatory role in the cyclooxygenase mediated epithelial osmoregulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121411.RARToz3D_QFpORjRlgK8P9RoKHvR70xAmq36lDdmTAdCg130_provenance.
- NP121413.RAXjwBaeXRSpfoqQ-DfbAf_TdEPymtYke8GA5MAXUVLgw130_assertion description "[Impaired expression of proteasome subunits is involved in the loss of HLA class I expression in human colon cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121413.RAXjwBaeXRSpfoqQ-DfbAf_TdEPymtYke8GA5MAXUVLgw130_provenance.
- NP121424.RAU6rejKFibwzxUEumOYXsYuKDNcoHf6h6hyA92Va3hlE130_assertion description "[Frequent mutations in CHEK1 (5%) damage response axis in colon cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121424.RAU6rejKFibwzxUEumOYXsYuKDNcoHf6h6hyA92Va3hlE130_provenance.
- NP121427.RAQe65HQEaA-2z88pFJbQ2FdHrseE0FoFTB4F7APHWzQg130_assertion description "[Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121427.RAQe65HQEaA-2z88pFJbQ2FdHrseE0FoFTB4F7APHWzQg130_provenance.
- NP121438.RAd2wYjPwZsk8kGOpizd1SvDyO2BxOo4TWH_yyIgSYtBs130_assertion description "[CD44-induced cell migration is dependent on its complex formation with Lyn and its consequent regulation of AKT phosphorylation in colon cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121438.RAd2wYjPwZsk8kGOpizd1SvDyO2BxOo4TWH_yyIgSYtBs130_provenance.
- NP121439.RAQqSrJ8h8MilXVF4_6oFzG8dLW2gaIXCI-rmF4OdISKY130_assertion description "[Disruption of signaling through MKK7 yields differential response in hypoxic colon cancer cells treated with oxaliplatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121439.RAQqSrJ8h8MilXVF4_6oFzG8dLW2gaIXCI-rmF4OdISKY130_provenance.
- NP121444.RASULK6rbjqjjUfFWGmmqeiwU8E7d7eWcfUAoqSzdT05A130_assertion description "[Use of the adeno-associated virus mediated survivan mutant (Cys84Ala) is a promising strategy in colon cancer gene therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121444.RASULK6rbjqjjUfFWGmmqeiwU8E7d7eWcfUAoqSzdT05A130_provenance.
- NP121447.RAeRrWYqyPfI6ZOkffRqzrCSQ0oCWbnSHYwlm5DF-BDCg130_assertion description "[CLIC1 and TPD52 were significantly (P < 0.05) up-regulated in all cases of colorectal cancer investigated, irrespective of localization, pTNM stage and grade of colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121447.RAeRrWYqyPfI6ZOkffRqzrCSQ0oCWbnSHYwlm5DF-BDCg130_provenance.
- NP121452.RAbkTlAzKY3155eJ5w7NKOhGgYiC-oTfgS5M8wQbPj0sk130_assertion description "[Interactions of AChE with caveolin-1 and subsequently with cytochrome c appear to be indispensable for apoptosome formation in a colon cancer cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121452.RAbkTlAzKY3155eJ5w7NKOhGgYiC-oTfgS5M8wQbPj0sk130_provenance.
- NP121456.RAf6H-e36MeR23_gD-cYgcdDtgETpdz_zTIv7iAwx38dQ130_assertion description "[Among MYB regulation, the most dynamic is the control of transcriptional elongation by sequences within intron 1, this regulatory sequence is transcribed into an RNA stem-loop and 19-residue polyuridine tract, and is subject to mutation in colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121456.RAf6H-e36MeR23_gD-cYgcdDtgETpdz_zTIv7iAwx38dQ130_provenance.
- NP121457.RAUG4_OOi3FLqRVkhOm8KAGh9df76wBon7aC9fdftoNmU130_assertion description "[No correlation between the pretherapeutic PDGFRbeta and c-kit mRNA expression in colon cancer treaeted with cetuximab.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121457.RAUG4_OOi3FLqRVkhOm8KAGh9df76wBon7aC9fdftoNmU130_provenance.
- NP121464.RAdNXAZTFrDCmnEd6tGh2wG8QRbukT3C3x5AO9hVkg9sg130_assertion description "[Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121464.RAdNXAZTFrDCmnEd6tGh2wG8QRbukT3C3x5AO9hVkg9sg130_provenance.
- NP121468.RAa4S72_Zl20nG-06skcSReRQm3kSJsJD79sR6V7w7YVM130_assertion description "[up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121468.RAa4S72_Zl20nG-06skcSReRQm3kSJsJD79sR6V7w7YVM130_provenance.
- NP121471.RAeJIz9xPyZmulP71UtP_NI30PqkXMpeD83SayGLJglEw130_assertion description "[Galectin-3 up-regulation of MUC2 transcription occurs at the level of transcription through AP-1 activation in colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121471.RAeJIz9xPyZmulP71UtP_NI30PqkXMpeD83SayGLJglEw130_provenance.
- NP121473.RAcPtklS8sE-wYsLiIc_67vodEuWTeRamFv5leNL6VkWI130_assertion description "[k-ras has a role in cell death through the p38 MAP kinase pathway in human colonic cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121473.RAcPtklS8sE-wYsLiIc_67vodEuWTeRamFv5leNL6VkWI130_provenance.
- NP121474.RAV3EupTN59hlXn0IlgzUFqUX6ltx86uy8TFqvDrS-hos130_assertion description "[association of L-plastin overexpression with increased rate of proliferation and invasion, and loss of E-cadherin expression in the SW480 colon cancer cell line indicates that L-plastin plays an important mechanistic role in colorectal cancer metastasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121474.RAV3EupTN59hlXn0IlgzUFqUX6ltx86uy8TFqvDrS-hos130_provenance.
- NP121477.RAVR9Qu4MwkW-qdaVF2hBGoHNCNXRQGLJa_di3EU-5rkw130_assertion description "[The effect of XIAP inhibition and PPARgamma activation in colon cancer, was explored.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121477.RAVR9Qu4MwkW-qdaVF2hBGoHNCNXRQGLJa_di3EU-5rkw130_provenance.
- NP121479.RAREAZEF-Gkyhs9RKOWAHWb27kHEdZI10MlodBTCPuhqU130_assertion description "[Gastrin and ghrelin serum levels were respectively slightly higher and significantly lower in colon cancer patients than in controls/levels were higher in left colon cancer and H.pylori infection while ghrelin levels were lower in both groups ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121479.RAREAZEF-Gkyhs9RKOWAHWb27kHEdZI10MlodBTCPuhqU130_provenance.
- NP121489.RAQagDeVWy4cD1NK3Hg4yLFor4huw3DMXh2W5HkkPZErY130_assertion description "[the N-terminal region of the APC protein mediated its junctional localisation, consistent with the observation that truncated APC proteins in colon cancer cell lines are still capable of localising to the cell cortex ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121489.RAQagDeVWy4cD1NK3Hg4yLFor4huw3DMXh2W5HkkPZErY130_provenance.
- NP121490.RAfrvMpI5fXFi0NDp0g7Myw1vab2kKwBZn52pPsUrkF5M130_assertion description "[The cloning of a novel beta1, 3-N-acetylglucosaminyltransferase that is upregulated in a human colon cancer cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121490.RAfrvMpI5fXFi0NDp0g7Myw1vab2kKwBZn52pPsUrkF5M130_provenance.
- NP121492.RAVvyEbhBguu8sA_viuHFU_RDdiYUvWA7d5I07dsudsHk130_assertion description "[huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121492.RAVvyEbhBguu8sA_viuHFU_RDdiYUvWA7d5I07dsudsHk130_provenance.
- NP121494.RAY0xMBMj6imtek-o8KI8KcDS5fHFwY5ZgRnqrlGNaUtc130_assertion description "[A 2315-Da peptide found only in medium from SFC colon cancer cell lines was identified and shown to consist of a portion of both the extracellular and transmembrane regions of human podocalyxin-like 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121494.RAY0xMBMj6imtek-o8KI8KcDS5fHFwY5ZgRnqrlGNaUtc130_provenance.
- NP121496.RAWHZMvvq5xuXOhAdgRg6AOWZDTenHAK-PF85W4imiOVQ130_assertion description "[Expression is not prognostic of survival in colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121496.RAWHZMvvq5xuXOhAdgRg6AOWZDTenHAK-PF85W4imiOVQ130_provenance.
- NP121497.RAahEtBn0KTHhxVyAomiTgtajOZUIph7W_pEW-86538TE130_assertion description "[The relationship of nuclear to cytoplasmic thymidylate synthase expression, given as a ratio of continuous AQUA scores, is a strong predictor of colon cancer survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121497.RAahEtBn0KTHhxVyAomiTgtajOZUIph7W_pEW-86538TE130_provenance.
- NP121499.RAWl3geNVxX1XC2gQskBpqiPF3aisHHvdd4pCp-rmnbtQ130_assertion description "[role in activating extracellular signal-regulated/mitogen-activated protein kinase and implication in metastatic spread of colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121499.RAWl3geNVxX1XC2gQskBpqiPF3aisHHvdd4pCp-rmnbtQ130_provenance.
- NP121501.RAW6FUjR0kYTLxZWFljUNnDteQlUZBcdx2nrhw5aNNrmc130_assertion description "[Ciglitazone induces NF-Kappa B transcriptional activity in colon cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121501.RAW6FUjR0kYTLxZWFljUNnDteQlUZBcdx2nrhw5aNNrmc130_provenance.
- NP121503.RAYrkSXkFaU3kilibp4FGzX2nVXGo08_N4vCGW_ARtVww130_assertion description "[CCR7 plays a critical role in mediating chemotactic and invasive responses in colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121503.RAYrkSXkFaU3kilibp4FGzX2nVXGo08_N4vCGW_ARtVww130_provenance.
- NP121504.RAVeTAXDIP5bapBouDjCk8cDgYN7eAUPxUnAeYpXxiZV0130_assertion description "[SSAT has a role in apoptosis induced by sulindac sulfone, which leads to reduced tissue polyamine contents in human colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121504.RAVeTAXDIP5bapBouDjCk8cDgYN7eAUPxUnAeYpXxiZV0130_provenance.
- NP121507.RAfq-fo48_87y2Cchsj76XzZ34qtJm50aUc7kGUyN_kIM130_assertion description "[Theses results suggest that CD40 is present in colon cancer, and recombinant soluble human CD40 ligand may be of clinical use to inhibit human colon cancer growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121507.RAfq-fo48_87y2Cchsj76XzZ34qtJm50aUc7kGUyN_kIM130_provenance.
- NP121508.RAcCkrC3hRtFPTy6NVs-LNiF_9V5st1NryiU6APUJcM3g130_assertion description "[Impaired expression of proteasome subunits is involved in the loss of HLA class I expression in human colon cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121508.RAcCkrC3hRtFPTy6NVs-LNiF_9V5st1NryiU6APUJcM3g130_provenance.
- NP121518.RAUquGAjBSaPu6w2Y2he6Q7p0Q2r9LSNSV4St_hoiE4q0130_assertion description "[Loss of claudin-1 expression proved to be a strong predictor of disease recurrence and poor patient survival in stage II colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121518.RAUquGAjBSaPu6w2Y2he6Q7p0Q2r9LSNSV4St_hoiE4q0130_provenance.
- NP121520.RAYOiRyn3h-cMY1ns7bgHOTn3fQ4-o3f8exnFqxNiNCsQ130_assertion description "[ADAM10 overexpression in colon cancer cells displaying endogenous L1-CAM enhanced L1-CAM cleavage and induced liver metastasis, and ADAM10 also enhanced metastasis in colon cancer cells stably transfected with L1-CAM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121520.RAYOiRyn3h-cMY1ns7bgHOTn3fQ4-o3f8exnFqxNiNCsQ130_provenance.
- NP121524.RAR2MBM3PfFxgdf-i1IiLpAhgQAcdTGpZ6TUVc_Hk1wWM130_assertion description "[inactivation of CLUAP1 may conceivably serve in the future as a novel therapeutic intervention for treatment of colon cancer ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121524.RAR2MBM3PfFxgdf-i1IiLpAhgQAcdTGpZ6TUVc_Hk1wWM130_provenance.
- NP121529.RAWMuJWKEpiitXfTS_a14IM40nUEHdeIRr8EcB6kxkVho130_assertion description "[Here we describe CD200 co-expression with stem cell markers found on prostate, breast, brain, and colon cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121529.RAWMuJWKEpiitXfTS_a14IM40nUEHdeIRr8EcB6kxkVho130_provenance.
- NP121540.RAbjUQoP3eV_kNxa_DoQ4hwFoIQ76ovS_zTqXs4davW4s130_assertion description "[Report shows that adenosine downregulation of DPPIV of colon cancer cells is mediated by an increase in protein tyrosine phosphatase activity that leads to a decrease in the tyrosine phosphorylation of ERK1/2 MAP kinase that links to the decline in DPPIV.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121540.RAbjUQoP3eV_kNxa_DoQ4hwFoIQ76ovS_zTqXs4davW4s130_provenance.
- NP121541.RAVERmuXhvu6b2j_VtL_1_BVk-b7t16SOSJopli0Aazsc130_assertion description "[ARC is a novel marker of human colon cancer and suggest that it may be a general feature of epithelial cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121541.RAVERmuXhvu6b2j_VtL_1_BVk-b7t16SOSJopli0Aazsc130_provenance.
- NP121543.RAanPNC_X-K5ATvilX6R4eIZ1AJd3XeuwJrTFyWiyTa5E130_assertion description "[CRP was identified in the blood of colon neoplasm patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121543.RAanPNC_X-K5ATvilX6R4eIZ1AJd3XeuwJrTFyWiyTa5E130_provenance.
- NP121547.RAQQzradVwsgd_Z08Ab1moZDH9PG8QFIJAYY_shGqXZpc130_assertion description "[Conclude that PPARgamma activation is essential to elicit the anti-carcinogenic action of herbal isoprenols in colonic cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121547.RAQQzradVwsgd_Z08Ab1moZDH9PG8QFIJAYY_shGqXZpc130_provenance.
- NP121550.RAdH-6vPmt_efMZamACNrYIyvMqe11QxvVr5As-JFjZk8130_assertion description "[ERK1/2 and JNK1/2 signaling is stimulated by radiation and can promote cell cycle progression in human colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121550.RAdH-6vPmt_efMZamACNrYIyvMqe11QxvVr5As-JFjZk8130_provenance.
- NP121551.RAVXJhPi5gSuMo7hVKeBzLclZgh-7ZznFF3QJd0Nn9LhE130_assertion description "[ERK1/2 and p38 MAPK have roles in suppressing apoptosis of colon cancer cells via cyclic AMP ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121551.RAVXJhPi5gSuMo7hVKeBzLclZgh-7ZznFF3QJd0Nn9LhE130_provenance.
- NP121554.RATaro7V-ImevagmD_yJNHoB8P7dlrriN5bBTzI1vJ-jE130_assertion description "[results demonstrate a critical role for PKCdelta/NF-kappaB in the regulation of FLIP in human colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121554.RATaro7V-ImevagmD_yJNHoB8P7dlrriN5bBTzI1vJ-jE130_provenance.
- NP121556.RASDvXNHXZfAZnB6j1GFG1BzcICeO0UbW215e_JnH_mRE130_assertion description "[Galectin-3 up-regulation of MUC2 transcription occurs at the level of transcription through AP-1 activation in colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121556.RASDvXNHXZfAZnB6j1GFG1BzcICeO0UbW215e_JnH_mRE130_provenance.
- NP121557.RATZGonlkNkKQs0s17DlA3G9fRL3FDEHgV547r_lOrZlk130_assertion description "[Leptin stimulates proliferation and inhibits apoptosis in colon cancer cells/effect involves JAK2, PI3 kinase and JNK and activation of the oncogenic transcription factors signal transducer and activator of transcription ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121557.RATZGonlkNkKQs0s17DlA3G9fRL3FDEHgV547r_lOrZlk130_provenance.
- NP121563.RAcEwvN3T05Crq8vCyA9IVe124zxpWNiDlc7Yi40109zY130_assertion description "[Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121563.RAcEwvN3T05Crq8vCyA9IVe124zxpWNiDlc7Yi40109zY130_provenance.
- NP121564.RAaODXeTZalfI_x5qWM_uEK9L-rvYLnElA1V1VWq-839E130_assertion description "[We found that the carrying rate of allele CXCL12-A was higher in colon cancer patients compared with rectal cancer patients (P = 0.017)/by ELISA showed that CRC patients (n = 63) had a lower CXCL12 plasma level compared with controls (P < 0.0001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121564.RAaODXeTZalfI_x5qWM_uEK9L-rvYLnElA1V1VWq-839E130_provenance.
- NP121568.RAWgLiVb7phUPJwo916dridK23hrSCKDNTxgRvdxDrC7Q130_assertion description "[Leptin stimulates proliferation and inhibits apoptosis in colon cancer cells/effect involves JAK2, PI3 kinase and JNK and activation of the oncogenic transcription factors signal transducer and activator of transcription ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121568.RAWgLiVb7phUPJwo916dridK23hrSCKDNTxgRvdxDrC7Q130_provenance.
- NP121570.RAVFqU9MzUGQjqiv-xjYLy0s8yF4mtazmNMZOZ5KN7CiA130_assertion description "[investigated whether colon cancer was associated with genetic variations in UGT1A1 and UGT1A9 genes and we determined if those variations modify the association between colon cancer and dietary HCA and PAH exposure ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121570.RAVFqU9MzUGQjqiv-xjYLy0s8yF4mtazmNMZOZ5KN7CiA130_provenance.
- NP121573.RAYMGU-EVLJeVVxD5wI52wD6wlgG3LuRkcRqMCSeSauho130_assertion description "[Expressed in colon cancer cells ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121573.RAYMGU-EVLJeVVxD5wI52wD6wlgG3LuRkcRqMCSeSauho130_provenance.
- NP121582.RAXx4o0FEKRmlLdLihRJgRL3LehLFzSxzK7mQxvBtZsIM130_assertion description "[association of the CARD15 genotype with behaviour and location of Inflammatory Bowel Diseases holds also for the Italian population ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121582.RAXx4o0FEKRmlLdLihRJgRL3LehLFzSxzK7mQxvBtZsIM130_provenance.
- NP121585.RAar2gNU4WPrFN-oegkKwIc8wfD1JRSuU3NQIz2H9-ib4130_assertion description "[Activation of transcription factor nuclear factor (NF) -kappaB, which controls transcription of various pro-inflammatory cytokine genes, has been shown to play a critical role in the pathogenesis of inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121585.RAar2gNU4WPrFN-oegkKwIc8wfD1JRSuU3NQIz2H9-ib4130_provenance.
- NP121591.RASBcPg7CTb3yZdOJFv7jE4zs2sr9BSo4l0KchuJ2-u9c130_assertion description "[The FCRL3 gene is involved in inflammatory bowel disease (IBD) genetic susceptibility by an epistatic interaction with HLA-DRB1*0103.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121591.RASBcPg7CTb3yZdOJFv7jE4zs2sr9BSo4l0KchuJ2-u9c130_provenance.
- NP121592.RAUNmATlEY8B_f5yykD7OXBAnVhdxBi6ErPQPCzD8AOGo130_assertion description "[combined alpha-methylacyl coenzyme A racemase/p53 analysis may represent a helpful tool to confirm dysplasia in inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121592.RAUNmATlEY8B_f5yykD7OXBAnVhdxBi6ErPQPCzD8AOGo130_provenance.
- NP121593.RARL6oRzzOFV7Fo0x1IoW7t_WnK6_JJ-BN6zwUrU96Bck130_assertion description "[Galectin-3 modulates T cell activity and is reduced in the inflamed intestinal epithelium in inflammatory bowel disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121593.RARL6oRzzOFV7Fo0x1IoW7t_WnK6_JJ-BN6zwUrU96Bck130_provenance.
- NP121599.RAZK0nHhisVhelksN4YBpS432lzZfC3BW0p6RHsZml9Sc130_assertion description "[PON1/2/3 may have extracellular functions as part of the host response in inflammatory bowel diseases and celiac disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121599.RAZK0nHhisVhelksN4YBpS432lzZfC3BW0p6RHsZml9Sc130_provenance.
- NP121604.RAWVY7WLRcGVeW9ShS0V4sHqja-VdEhPJvwOjJbHMmfwY130_assertion description "[-857 polymorphism does not contribute to susceptibility of inflammatory bowel disease, nor does it define the phenotype of Crohn's disease in Israeli Jewish patients with inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121604.RAWVY7WLRcGVeW9ShS0V4sHqja-VdEhPJvwOjJbHMmfwY130_provenance.
- NP121605.RAcDkbC95KWFyOGfwhg6FEzADi-vuSu50VxEtRk37JAXw130_assertion description "[TNF-alpha is a key cytokine known to play a role in inflammatory response, and the locus for the gene is found in the IBD3 region on chromosome 6p21, known to be associated with an increased risk for inflammatory bowel diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121605.RAcDkbC95KWFyOGfwhg6FEzADi-vuSu50VxEtRk37JAXw130_provenance.
- NP121606.RAfESkDjQ7iEBVyK87_ddhQRbzjqr9G8wN0_qoHGFO-lA130_assertion description "[the frequency of functional gene polymorphisms in 396 patients with inflammatory bowel disease and 300 healthy subjects ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121606.RAfESkDjQ7iEBVyK87_ddhQRbzjqr9G8wN0_qoHGFO-lA130_provenance.
- NP121610.RAZk5GZuynYkQendu-PcJb10tXnpNNYALXRx-Cd_f-vOs130_assertion description "[case control analysis demonstrates a disease association with the IL-23R (interleukin 23 receptor) locus and implicates the same polymorphisms associated with Inflammatory Bowel Disease and psoriasis ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121610.RAZk5GZuynYkQendu-PcJb10tXnpNNYALXRx-Cd_f-vOs130_provenance.
- NP121612.RAZ8_bZF1Vgn9Wj5M5Yt7qzn_8hwWNCW2cEQomdQ_QHYk130_assertion description "[Single nucleotide polymorphism in IL23R is associated with inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121612.RAZ8_bZF1Vgn9Wj5M5Yt7qzn_8hwWNCW2cEQomdQ_QHYk130_provenance.
- NP121615.RAWzSSapADQpNUl2b7PtIgW_6vtJLWFAoE76fjSGbPMU0130_assertion description "[the PC pathway has an important role in governing intestinal microvascular inflammation and might provide a novel therapeutic target in the management of inflammatory bowel disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121615.RAWzSSapADQpNUl2b7PtIgW_6vtJLWFAoE76fjSGbPMU0130_provenance.
- NP121621.RAZQ-Ic9ONDPtS5yglpLU827eaUZkPjQeF1Iqw9gY8ccs130_assertion description "[The identification of the IBD1 gene on chromosome 16 as NOD-2 is unquestionably an important scientific discovery of the genetics of the inflammatory bowel diseases, Crohn's disease and ulcerative colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121621.RAZQ-Ic9ONDPtS5yglpLU827eaUZkPjQeF1Iqw9gY8ccs130_provenance.
- NP121623.RAdYctuUGUQofKPLTXshgXLLKT55qtxZtGnTK4d6ZqVEI130_assertion description "[CD1d-restricted NKT cells have roles in the intestine and in inflammatory bowel diseases [review]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121623.RAdYctuUGUQofKPLTXshgXLLKT55qtxZtGnTK4d6ZqVEI130_provenance.
- NP121631.RAZjVcEkdiMZEmw3tLPjqGnoiyDGyD53UlT6HBs0FbxwE130_assertion description "[A direct role for IL12B in susceptibility to inflammatory bowel disease is unlikely.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121631.RAZjVcEkdiMZEmw3tLPjqGnoiyDGyD53UlT6HBs0FbxwE130_provenance.
- NP121638.RAWwxcYu9ku0gpLN14seqtHI9gDHTf7e_pa0GYyrTLNsM130_assertion description "[Reduced serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in adults with inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121638.RAWwxcYu9ku0gpLN14seqtHI9gDHTf7e_pa0GYyrTLNsM130_provenance.
- NP121647.RAQQMFXXlLYABeLL24dMpT6cAr4yzZ3AlPjQ2TwHJl0HE130_assertion description "[inflammatory bowel disease susceptibility ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121647.RAQQMFXXlLYABeLL24dMpT6cAr4yzZ3AlPjQ2TwHJl0HE130_provenance.
- NP121648.RARw2e9ZwT8aunwpWTf3w5lzmLiL7NKDfFFDdDpCarGWU130_assertion description "[results demonstrate that epithelial eotaxin-3 is up-regulated in the context of a T helper 2 mediated inflammatory bowel disease via the signal transducer and activator of transcription 6 ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121648.RARw2e9ZwT8aunwpWTf3w5lzmLiL7NKDfFFDdDpCarGWU130_provenance.
- NP121650.RAUcaMmdfkWlDlgWkGV5RJRtvS8l4zTXP8UUp855wPNq0130_assertion description "[The expression patterns of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease (IBD) may indicate their contribution in epithelial cell turnover and their possible implication in IBD-related dysplasia-carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121650.RAUcaMmdfkWlDlgWkGV5RJRtvS8l4zTXP8UUp855wPNq0130_provenance.
- NP121654.RAWGefg0LrS5YEXtsriLkPzty5_1fe9YgnuzrL-vPNWOA130_assertion description "[In patients with inflammatory bowel disease, plasma levels of visfatin are elevated and its mRNA expression is significantly increased in colonic tissue of Crohn's and ulcerative colitis patients ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121654.RAWGefg0LrS5YEXtsriLkPzty5_1fe9YgnuzrL-vPNWOA130_provenance.
- NP121658.RASo5Ru4sdNadvwGvw_W27hLvxRfcPydrEPgf9TR5Dgoc130_assertion description "[Determine OCTN1/2 and CARD15 gene polymorphisms in Chinese patients with inflammatory bowel disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121658.RASo5Ru4sdNadvwGvw_W27hLvxRfcPydrEPgf9TR5Dgoc130_provenance.
- NP121659.RAabLZxJO16DaLXLdd6iY1LkJ2luao_ezRhqyskT7DjtQ130_assertion description "[antibody raised to an epitope during C.jejuni or M.paratuberculosis enterocolitis may crossreact with an intestinal epithelial cell functional variant of OCTN1, an already less efficient carnitine transporter, initiating inflammatory bowel disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP121659.RAabLZxJO16DaLXLdd6iY1LkJ2luao_ezRhqyskT7DjtQ130_provenance.